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Des Moines

Find cheap American Airlines flights to Des Moines

RDU — DSM
Aug 26 — Sep 21
Wed 8/26
Wed 9/2
1 adult, Economy
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Find American Airlines flight deals to Des Moines

Cheapest American Airlines flights from USA to Des Moines
Explore the most affordable American Airlines flight options available from USA to Des Moines. Find the lowest fares with prices last updated on July 27, 2026.

This American Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/205:44 pm
DEN
-
DSM
1 stop5h 36m
American Airlines
Mon 8/246:22 pm
DSM
-
DEN
1 stop4h 53m
American Airlines
Deal found 7/26$237
This American Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/259:16 am
DEN
-
DSM
1 stop4h 56m
American Airlines
Fri 8/286:22 pm
DSM
-
DEN
1 stop4h 53m
American Airlines
Deal found 7/24$266
This American Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/204:40 pm
IAH
-
DSM
1 stop7h 40m
American Airlines
Thu 8/274:13 pm
DSM
-
IAH
1 stop6h 07m
American Airlines
Deal found 7/23$269

Flights to Des Moines with American Airlines at a glance

Find detailed information about American Airlines flights from USA to Des Moines. Explore the options provided by American Airlines to plan your journey from USA to Des Moines. Data last updated July 27, 2026.

Popular in

June

Cheapest in

October

Average price

$422

Round-trip from

$237

One-way from

$119

Good one-way deal

$137 or less
Highest demand for flights to Des Moines with American Airlines; 7% potential price increase.
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Best time to find cheap flights to Des Moines with American Airlines; 0% potential price drop.
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Average price for flights to Des Moines with American Airlines (round-trip).
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American Airlines
  • American Airlines
  • 8/20-8/24
  • 2 total stops
  • 10h 29m total
  • USA to Des Moines
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American Airlines
  • American Airlines
  • 8/20
  • 1 total stop
  • 5h 36m total
  • USA to Des Moines
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Price to beat on a one-way flight from the United States to Des Moines with American Airlines.
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Cheapflights Insights

Find cheap American Airlines flights to Des Moines

How long is the flight to Des Moines with American Airlines?

On average, American Airlines flights from the United States to Des Moines take 2 hours 16 minutes. Flights to Des Moines from other popular cities in the United States will vary in length. Below are a few examples of popular routes and their flight times.

American Airlines weekly flight availability to Des Moines

The most flights to Des Moines operated by American Airlines are scheduled on a Friday (21 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (18 on average).

When is the best time to book a flight to Des Moines with American Airlines?

The best time to book a flight to Des Moines with American Airlines is 63 days before departure. On average, fares are higher if you book 54 days before departure.

When is the cheapest time to fly to Des Moines with American Airlines?

Users looking for the cheapest American Airlines fares to Des Moines should consider flying on Saturday mornings, when prices are typically cheapest. Budget-minded travellers will want to avoid Sunday at noon, when prices are usually at their highest.

FAQs about flights to Des Moines with American Airlines

  • Which airport do American Airlines flights arrive at when travelling to Des Moines?

    American Airlines flights on this route tend to land at Des Moines Airport.

  • Is American Airlines the cheapest airline for a flight to Des Moines?

    Flight prices will depend on many factors like date, time and cabin class so it is worth comparing flights before booking. Based on Cheapflights data the cheapest average return price for flights to Des Moines tends to be with Allegiant Air.

  • Are there alternative airlines other than American Airlines that fly to Des Moines?

    United Airlines, Delta and Allegiant Air all fly to Des Moines and offer an alternative to American Airlines.

  • How much is a flight to Des Moines with American Airlines?

    The average price for a return flight with American Airlines is $453; with a one-way flight around $276.

See more FAQs

Reviews of American Airlines

See what Cheapflights users have to say about their American Airlines experience.
American Airlines
7.1
Good
10,000 reviews
Overview

Boarding

7.5

Crew

7.9

Food

6.4

Comfort

7.2

Entertainment

6.8

Popular American Airlines flights

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