$220+ Cheap flights from Melbourne, FL to Des Moines (MLB - DSM)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/21. Fares are subject to change and may not be available on all flights or dates of travel.
MLB — DSM
Oct 9 — Oct 161
Round-trip
1 adult, Economy
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Find cheap flights from Melbourne to Des Moines with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Melbourne to Des Moines
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Cheapest flights from Melbourne to Des MoinesExplore the most affordable flight options available from Melbourne to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 9, 2026.
Explore the most affordable flight options available from Melbourne to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 9, 2026.
This Delta deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:44 pm -
1 stop4h 49m
Mon 10/123:03 pm -
1 stop6h 56m
Deal found 9/5![Delta logo]()
$504
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/17:25 am -
1 stop5h 39m
Tue 10/61:15 pm -
2 stops8h 21m
Deal found 9/4![American Airlines logo]()
$516
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/75:44 pm -
1 stop7h 14m
Mon 10/122:26 pm -
2 stops7h 51m
Deal found 9/5![American Airlines logo]()
$529
This Delta deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:44 pm -
1 stop4h 49m
Wed 10/145:35 am -
1 stop7h 09m
Deal found 9/6![Delta logo]()
$540
This Delta deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/256:40 pm -
1 stop4h 46m
Sun 9/275:45 am -
1 stop7h 06m
Deal found 9/5![Delta logo]()
$557
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/236:40 pm -
1 stop4h 46m
Sun 9/275:45 am -
1 stop7h 06m
Deal found 9/8![Delta logo]()
$558
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2112:58 pm -
1 stop7h 50m
Fri 9/251:30 pm -
1 stop7h 47m
Deal found 9/6![American Airlines logo]()
$623
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/2312:58 pm -
1 stop7h 50m
Sun 9/276:00 am -
2 stops10h 44m
Deal found 9/8![American Airlines logo]()
$702
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2512:58 pm -
1 stop7h 50m
Sun 9/276:00 am -
2 stops10h 44m
Deal found 9/5![American Airlines logo]()
$710
Best flights from Melbourne to Des MoinesDiscover carefully curated flight deals from Melbourne to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 9, 2026.
Discover carefully curated flight deals from Melbourne to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 9, 2026.
This Delta deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:44 pm -
1 stop4h 49m
Mon 10/123:03 pm -
1 stop6h 56m
Deal found 9/5![Delta logo]()
$504
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/17:25 am -
1 stop5h 39m
Tue 10/61:15 pm -
2 stops8h 21m
Deal found 9/4![American Airlines logo]()
$516
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/75:44 pm -
1 stop7h 14m
Mon 10/122:26 pm -
2 stops7h 51m
Deal found 9/5![American Airlines logo]()
$529
This Delta deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/256:40 pm -
1 stop4h 46m
Sun 9/275:45 am -
1 stop7h 06m
Deal found 9/5![Delta logo]()
$557
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/236:40 pm -
1 stop4h 46m
Sun 9/275:45 am -
1 stop7h 06m
Deal found 9/8![Delta logo]()
$558
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/2312:58 pm -
1 stop7h 50m
Sun 9/276:00 am -
2 stops10h 44m
Deal found 9/8![American Airlines logo]()
$702
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2512:58 pm -
1 stop7h 50m
Sun 9/276:00 am -
2 stops10h 44m
Deal found 9/5![American Airlines logo]()
$710
This Delta deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:40 pm -
1 stop4h 46m
Tue 10/63:03 pm -
1 stop6h 56m
Deal found 9/4![Delta logo]()
$740
This Delta deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/132:30 pm -
1 stop4h 39m
Wed 10/146:00 am -
2 stops6h 44m
Deal found 9/6![Delta logo]()
$1,636
Last-minute flights from Melbourne to Des MoinesDiscover last-minute flight deals from Melbourne to Des Moines. Data last updated September 9, 2026 and is based on user searches.
Discover last-minute flight deals from Melbourne to Des Moines. Data last updated September 9, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2112:58 pm -
1 stop7h 50m
Fri 9/251:30 pm -
1 stop7h 47m
Deal found 9/6![American Airlines logo]()
$623
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/236:40 pm -
1 stop4h 46m
Sun 9/275:45 am -
1 stop7h 06m
Deal found 9/8![Delta logo]()
$558
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/2312:58 pm -
1 stop7h 50m
Sun 9/276:00 am -
2 stops10h 44m
Deal found 9/8![American Airlines logo]()
$702
This Delta deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/256:40 pm -
1 stop4h 46m
Sun 9/275:45 am -
1 stop7h 06m
Deal found 9/5![Delta logo]()
$557
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2512:58 pm -
1 stop7h 50m
Sun 9/276:00 am -
2 stops10h 44m
Deal found 9/5![American Airlines logo]()
$710
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/17:25 am -
1 stop5h 39m
Tue 10/61:15 pm -
2 stops8h 21m
Deal found 9/4![American Airlines logo]()
$516
This Delta deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:44 pm -
1 stop4h 49m
Mon 10/123:03 pm -
1 stop6h 56m
Deal found 9/5![Delta logo]()
$504
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/75:44 pm -
1 stop7h 14m
Mon 10/122:26 pm -
2 stops7h 51m
Deal found 9/5![American Airlines logo]()
$529
This Delta deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:44 pm -
1 stop4h 49m
Wed 10/145:35 am -
1 stop7h 09m
Deal found 9/6![Delta logo]()
$540
One-way flights from Melbourne to Des MoinesSearch for one-way flight options from Melbourne to Des Moines. Find affordable one-way fares based on user searches. Data last updated September 9, 2026.
Search for one-way flight options from Melbourne to Des Moines. Find affordable one-way fares based on user searches. Data last updated September 9, 2026.
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/216:44 pm -
1 stop4h 49m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Delta logo]()
$220
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/236:48 pm -
1 stop4h 47m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Delta logo]()
$252
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/186:00 am -
1 stop5h 42m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Delta logo]()
$279
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/226:00 am -
2 stops13h 27m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![American Airlines logo]()
$358
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/2811:51 am -
2 stops11h 52m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![American Airlines logo]()
$388
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/216:00 am -
2 stops8h 28m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![American Airlines logo]()
$398
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3011:51 am -
2 stops8h 18m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![American Airlines logo]()
$420
Find flight deals from Melbourne to Des Moines
Discover tips and strategies to find the most affordable flight options for your journey from Melbourne (MLB) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 9, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $504 (Delta) |
One-way from | $220 (Delta) |
Popular in | August |
Cheapest in | November |
Average price | $332 |
Cheapflights Fare Finder
Customize your flight search to find flights from Melbourne to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 9, 2026.
Use the filters below to find and compare flights from Melbourne to Des Moines that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
MelbourneDes Moines
MLB Melbourne - DSM Des Moines
MLBDSM
Melbourne
Wed 10/21
6:44 pm-10:33 pm
1 stop4h 49m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$220
Quickest round-trip
MelbourneDes Moines
MLB Melbourne - DSM Des Moines
MLBDSM
Melbourne
Mon 11/23
6:48 pm-10:35 pm
1 stop4h 47m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$252
MelbourneDes Moines
MLB Melbourne - DSM Des Moines
MLBDSM
Melbourne
Mon 12/28
6:49 pm-10:38 pm
1 stop4h 49m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$279
MelbourneDes Moines
MLB Melbourne - DSM Des Moines
MLBDSM
Melbourne
Sat 11/21
6:00 am-10:51 am
1 stop5h 51m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$279
MelbourneDes Moines
MLB Melbourne - DSM Des Moines
MLBDSM
Melbourne
Sun 10/18
6:00 am-10:42 am
1 stop5h 42m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$279
MelbourneDes Moines
MLB Melbourne - DSM Des Moines
MLBDSM
Melbourne
Sun 11/22
6:00 am-10:51 am
1 stop5h 51m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$279
MelbourneDes Moines
MLB Melbourne - DSM Des Moines
MLBDSM
Melbourne
Tue 12/29
11:51 am-7:09 pm
2 stops8h 18m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$358
MelbourneDes Moines
MLB Melbourne - DSM Des Moines
MLBDSM
Melbourne
Wed 10/7
6:44 pm-10:33 pm
1 stop4h 49m
Des Moines
Mon 10/12
3:03 pm-10:59 pm
1 stop6h 56m
$504
MelbourneDes Moines
MLB Melbourne - DSM Des Moines
MLBDSM
Melbourne
Thu 10/1
7:25 am-12:04 pm
1 stop5h 39m
Des Moines
Tue 10/6
1:15 pm-10:36 pm
2 stops8h 21m
$516
MelbourneDes Moines
MLB Melbourne - DSM Des Moines
MLBDSM
Melbourne
Wed 10/7
5:44 pm-11:58 pm
1 stop7h 14m
Des Moines
Mon 10/12
2:26 pm-11:17 pm
2 stops7h 51m
$529
Showing 1-10 of 16 resultsSorted by cheapest first
Compare providers for flights from Melbourne to Des Moines
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Melbourne to Des Moines in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Melbourne, Florida-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Melbourne, Florida-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Melbourne, Florida-Des Moines flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Melbourne, Florida-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Melbourne, Florida-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Melbourne to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from Melbourne with our price prediction graph.
MLB-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Related info for your journey
Find useful and relevant information for your journey from Melbourne to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsAltoona
Clive
Ames
Johnston
Boone
Norwalk
West Des Moines
Ankeny
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