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Des Moines

$217+ Cheap flights from Melbourne, FL to Des Moines (MLB - DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/19. Fares are subject to change and may not be available on all flights or dates of travel.
MLB — DSM
Aug 26 — Sep 21
Wed 8/26
Wed 9/2
1 adult, Economy
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Cheap flight deals from Melbourne to Des Moines

Cheapest flights from Melbourne to Des Moines
Explore the most affordable flight options available from Melbourne to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 27, 2026.

This American Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1012:58 pm
MLB
-
DSM
1 stop7h 50m
American Airlines
Thu 9/241:30 pm
DSM
-
MLB
1 stop7h 47m
American Airlines
Deal found 7/24$431
This Delta deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/166:48 pm
MLB
-
DSM
1 stop4h 46m
Delta
Tue 12/222:15 pm
DSM
-
MLB
1 stop7h 27m
Delta
Deal found 7/26$445
This American Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2512:58 pm
MLB
-
DSM
1 stop7h 50m
American Airlines
Sun 9/2711:00 am
DSM
-
MLB
1 stop5h 44m
American Airlines
Deal found 7/23$512

Find flight deals from Melbourne to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Melbourne (MLB) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 27, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$431
(American Airlines)

One-way from

$217
(Delta)

Popular in

July

Cheapest in

October

Average price

$446
Provider with most accurate pricing for Melbourne-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Melbourne-Des Moines flights.
Search Deals
From Melbourne to Des Moines
Search Deals
One-way flight from Melbourne to Des Moines
Search Deals
Highest demand for flights based on searches. 18% potential increase in price ($66 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($14 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in July 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Melbourne to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 27, 2026.
Use the filters below to find and compare flights from Melbourne to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

MelbourneDes Moines

MLB - DSM

MLBDSM

Melbourne

Thu 9/10

12:58 pm-7:48 pm

1 stop7h 50m

Des Moines

Thu 9/24

1:30 pm-10:17 pm

1 stop7h 47m

$431
Quickest round-trip

MelbourneDes Moines

MLB - DSM

MLBDSM

Melbourne

Wed 12/16

6:48 pm-10:34 pm

1 stop4h 46m

Des Moines

Tue 12/22

2:15 pm-10:42 pm

1 stop7h 27m

$445

MelbourneDes Moines

MLB - DSM

MLBDSM

Melbourne

Fri 9/25

12:58 pm-7:48 pm

1 stop7h 50m

Des Moines

Sun 9/27

11:00 am-5:44 pm

1 stop5h 44m

$512
Cheapest one-way

MelbourneDes Moines

MLB - DSM

MLBDSM

Melbourne

Sat 9/19

6:00 am-10:46 am

1 stop5h 46m

$217

MelbourneDes Moines

MLB - DSM

MLBDSM

Melbourne

Thu 9/3

6:25 am-12:24 pm

1 stop6h 59m

$222

MelbourneDes Moines

MLB - DSM

MLBDSM

Melbourne

Thu 12/31

5:55 am-4:50 pm

2 stops11h 55m

$255

MelbourneDes Moines

MLB - DSM

MLBDSM

Melbourne

Thu 9/3

11:11 am-8:39 pm

2 stops10h 28m

$255
Quickest one-way

MelbourneDes Moines

MLB - DSM

MLBDSM

Melbourne

Wed 12/30

5:55 am-10:18 am

1 stop5h 23m

$269

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/23

Sorted by cheapest first

Compare providers for flights from Melbourne to Des Moines

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Melbourne to Des Moines in July.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*3 stars
ExpediaPrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Melbourne, Florida-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Melbourne, Florida-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Melbourne, Florida-Des Moines flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Melbourne, Florida-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Melbourne, Florida-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Melbourne to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Melbourne with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Melbourne to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Melbourne, Florida to Des Moines?

    American Airlines and Delta can get you from Melbourne, Florida to Des Moines in just under 4h 46m. Your travel time can differ by up to 3h 04m. There are 1182 mi between Melbourne, Florida and Des Moines. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Melbourne to Des Moines that include hotel bookings?

    Yes. In addition to deals on Melbourne to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Melbourne to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Melbourne to Des Moines.

  • Can I find deals for business class flights from Melbourne to Des Moines?

    Yes. Cheapflights offers flight deals from Melbourne to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Altoona
Ames
Clive
Johnston
Boone
West Des Moines
Ankeny

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