HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Santa Ana

$106+ Cheap flights from Des Moines to Santa Ana (DSM - SNA)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/16. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — SNA
Jul 8 — Jul 151
Tue 7/8
Tue 7/15
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Des Moines to Santa Ana with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from Des Moines to Santa Ana J. Wayne/Orange Cnty are usually found in September or August, booked 22 days in advance, depart on a Saturday or Thursday and return on a Wednesday

Cheap flight deals from Des Moines to Santa Ana

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Santa Ana (SNA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 3, 2025.

Round-trip from

$108
(Mytrip)

One-way from

$106
(Mytrip)

Popular in

November

Cheapest in

September

Average price

$396

Good round-trip deal

$128 or less

Good one-way deal

$123 or less
From Des Moines to Santa Ana J. Wayne/Orange Cnty
Search Deals
One-way flight from Des Moines to Santa Ana J. Wayne/Orange Cnty
Search Deals
Highest demand for flights based on searches. 18% potential increase in price ($66 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($13 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in July 2025
Search Deals
Price to beat on a round-trip flight from Des Moines to Santa Ana J. Wayne/Orange Cnty.
Search Deals
Price to beat on a one-way flight from Des Moines to Santa Ana J. Wayne/Orange Cnty.
Search Deals

Find flight deals from Des Moines to Santa Ana

Cheapest flights from Des Moines to Santa Ana
Explore the most affordable flight options available from Des Moines to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 3, 2025.

This Mytrip deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/287:00 amDSM - SNA
Nonstop3h 47mAllegiant Air
Sun 8/319:37 amSNA - DSM
Nonstop3h 18mAllegiant Air
Deal found 7/1$108
This Mytrip deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/17:30 amDSM - SNA
1 stop14h 15mMultiple Airlines
Sun 10/510:25 amSNA - DSM
Nonstop3h 19mMultiple Airlines
Deal found 7/2$175
This Trip.com deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/283:23 pmDSM - SNA
1 stop22h 01mFrontier
Sat 8/3012:04 pmSNA - DSM
1 stop24h 19mFrontier
Deal found 7/3$257
This Delta deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/37:00 amDSM - SNA
1 stop8h 00mDelta
Wed 9/108:00 amSNA - DSM
1 stop7h 12mDelta
Deal found 7/2$287
This American Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/155:30 amDSM - SNA
1 stop5h 32mAmerican Airlines
Mon 10/2010:23 amSNA - DSM
1 stop7h 48mAmerican Airlines
Deal found 7/2$339

Cheapflights Fare Finder

Customize your flight search to find flights from Des Moines to Santa Ana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 3, 2025.
Use the filters below to find and compare flights from Des Moines to Santa Ana that are best for you.

Fly from

Des Moines

Fly to

Santa Ana

Route

Depart

Return

Price

Des MoinesSanta Ana

DSM - SNA

DSMSNA

Des Moines

Thu 8/28

7:00 am-8:47 am

Nonstop3h 47m

Santa Ana J. Wayne/Orange Cnty

Sun 8/31

9:37 am-2:55 pm

Nonstop3h 18m

$108

Des MoinesSanta Ana

DSM - SNA

DSMSNA

Des Moines

Wed 10/1

7:30 am-7:45 pm

1 stop14h 15m

Santa Ana J. Wayne/Orange Cnty

Sun 10/5

10:25 am-3:44 pm

Nonstop3h 19m

$175

Des MoinesSanta Ana

DSM - SNA

DSMSNA

Des Moines

Thu 8/28

3:23 pm-11:24 am

1 stop22h 01m

Santa Ana J. Wayne/Orange Cnty

Sat 8/30

12:04 pm-2:23 pm

1 stop24h 19m

$257

Des MoinesSanta Ana

DSM - SNA

DSMSNA

Des Moines

Wed 9/3

7:00 am-1:00 pm

1 stop8h 00m

Santa Ana J. Wayne/Orange Cnty

Wed 9/10

8:00 am-5:12 pm

1 stop7h 12m

$287

Des MoinesSanta Ana

DSM - SNA

DSMSNA

Des Moines

Wed 10/15

5:30 am-9:02 am

1 stop5h 32m

Santa Ana J. Wayne/Orange Cnty

Mon 10/20

10:23 am-8:11 pm

1 stop7h 48m

$339

Des MoinesSanta Ana

DSM - SNA

DSMSNA

Des Moines

Wed 7/16

7:30 am-9:21 pm

1 stop15h 51m

$106

Des MoinesSanta Ana

DSM - SNA

DSMSNA

Des Moines

Tue 9/23

6:30 am-12:20 pm

2 stops7h 50m

$156

Des MoinesSanta Ana

DSM - SNA

DSMSNA

Des Moines

Sun 7/13

7:00 am-8:31 am

Nonstop3h 31m

$162

Des MoinesSanta Ana

DSM - SNA

DSMSNA

Des Moines

Fri 7/18

7:33 pm-11:11 am

1 stop17h 38m

$166

Des MoinesSanta Ana

DSM - SNA

DSMSNA

Des Moines

Sun 8/17

5:44 am-10:53 am

1 stop7h 09m

$179

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/1

Showing 1-10 of 13 results
1
2

Best time to book a flight from Des Moines to Santa Ana

Have a flexible travel schedule? Discover the best time to fly to Santa Ana from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Santa Ana

How far ahead should I book a flight from Des Moines to Santa Ana?

Use this chart to determine the optimal time to book a round-trip flight from Des Moines to Santa Ana. Price data was last updated on June 27, 2025.

To ensure you get the cheapest price possible for a flight from Des Moines to Santa Ana, you should look to book at least 21 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Des Moines to Santa Ana?

Currently, January is the cheapest month in which you can book a flight from Des Moines to Santa Ana (average of $298). Flying from Des Moines to Santa Ana in March is currently the most expensive (average of $377). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to SNA?

Find hourly flight availability from Des Moines to Santa Ana. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 3, 2025.

A simple way to save on the total cost of your ticket is to fly from Des Moines to Santa Ana at noon. If you’re flexible enough to do this you can expect to save up to 38% on your trip compared to booking a flight in the morning.

Reviews of airlines servicing Santa Ana

Get insights into the airlines that provide service to Santa Ana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Ana. Reviews last updated July 3, 2025.
Read through reviews of airlines operating flights from Des Moines to Santa Ana, such as Alaska Airlines, Southwest, and Delta. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
10,000 reviews

Comfort

7.8

Food

7.1

Overall

8.0

Crew

8.5

Entertainment

7.1

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Alaska Airlines
8.0
Very good
10,000 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Comfort

7.8

Food

7.1

Overall

8.0

Crew

8.5

Entertainment

7.1

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Southwest
8.0
Very good
4,266 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Comfort

7.8

Food

7.1

Overall

8.0

Crew

8.5

Entertainment

7.1

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Delta
8.0
Very good
7,982 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Comfort

7.8

Food

7.1

Overall

8.0

Crew

8.5

Entertainment

7.1

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
United Airlines
7.4
Good
8,861 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Comfort

7.8

Food

7.1

Overall

8.0

Crew

8.5

Entertainment

7.1

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
American Airlines
7.2
Good
10,000 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Comfort

7.8

Food

7.1

Overall

8.0

Crew

8.5

Entertainment

7.1

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Santa Ana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Des Moines to Santa Ana flight route?

    This flight path from Des Moines to Santa Ana J. Wayne/Orange Cnty was viewed by 8 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • What are the cheapest airlines flying from Des Moines to Santa Ana round-trip?

    According to our current data, Allegiant Air ($108), Frontier ($257), and Delta ($287) offers the cheapest pricing from Des Moines to Santa Ana. Allegiant Air is currently priced 64% below the average price you’ll pay for this route.

  • What are the cheapest airlines to fly from Des Moines to Santa Ana one-way?

    The cheapest airline one-way is Southwest, with whom users have recently found tickets for as low as $156. However, be on the lookout for offers from Allegiant Air and Frontier, as they are both options that can get you from Des Moines to Santa Ana for a low price.

  • What are the cheapest flights from Des Moines to Santa Ana?

    On average you can expect to pay $206 for a flight from Des Moines to Santa Ana. The cheapest flight overall is $114 while the most popular route, (Des Moines - Santa Ana J. Wayne/Orange Cnty) is currently priced at $115.

  • Can I find deals for flights from Des Moines to Santa Ana that include hotel bookings?

    Yes. In addition to deals on Des Moines to Santa Ana flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Santa Ana?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Santa Ana.

  • Can I find deals for business class flights from Des Moines to Santa Ana?

    Yes. Cheapflights offers flight deals from Des Moines to Santa Ana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Santa Ana?

    Currently, January is the cheapest month in which you can book a flight from Des Moines to Santa Ana (average of $298). Flying from Des Moines to Santa Ana in March is currently the most expensive (average of $377). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Tustin

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Des Moines to Santa Ana

See prices for flight routes from nearby airports that may be better suited for you.
Omaha to Las Vegas flights
Des Moines to Las Vegas flights
Omaha to San Francisco flights
Omaha to Los Angeles flights
Omaha to San Diego flights
Cedar Rapids to Burbank flights
Omaha to Burbank flights
Des Moines to San Francisco flights
Des Moines to Los Angeles flights
Cedar Rapids to Las Vegas flights
Cedar Rapids to Los Angeles flights
Omaha to Ontario flights
Cedar Rapids to Ontario flights
Cedar Rapids to Santa Ana flights
Cedar Rapids to San Francisco flights
Moline to San Jose flights
Cedar Rapids to San Diego flights
Omaha to Sacramento flights
Omaha to Santa Ana flights
Des Moines to San Diego flights
Moline to Las Vegas flights
Moline to San Francisco flights
Moline to Ontario flights
Des Moines to Ontario flights
Moline to Los Angeles flights
Des Moines to San Jose flights
Cedar Rapids to Reno flights
Des Moines to Palm Springs flights
Des Moines to Reno flights
Omaha to Reno flights
Cedar Rapids to Sacramento flights
Des Moines to Burbank flights
Moline to San Diego flights
Omaha to Long Beach flights
Des Moines to Sacramento flights
Omaha to Palm Springs flights
Moline to Sacramento flights
Cedar Rapids to San Jose flights
Moline to Palm Springs flights
Cedar Rapids to Medford flights
Cedar Rapids to Fresno flights
Moline to Santa Ana flights
Omaha to Monterey flights
Des Moines to Fresno flights
Des Moines to Oakland flights
Des Moines to Santa Barbara flights
Omaha to Fresno flights
Omaha to Oakland flights
Cedar Rapids to Palm Springs flights

Top 4 airlines flying from Des Moines to Santa Ana

Discover the top 4 airlines that operate flights from Des Moines to Santa Ana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 3, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$106Average$211FlexibilityNo cancel feeOn-time88%
American AirlinesCheapest$298Average$406FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$298Average$472FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$401Average$504FlexibilityNo cancel feeOn-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.