$222+ Cheap flights from Des Moines to San Jose, CA (DSM - SJC)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/2. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — SJC
Oct 9 — Oct 161
Round-trip
1 adult, Economy
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Find cheap flights from Des Moines to San Jose with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Des Moines to San Jose
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Cheapest flights from Des Moines to San JoseExplore the most affordable flight options available from Des Moines to San Jose. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 9, 2026.
Explore the most affordable flight options available from Des Moines to San Jose. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 9, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/302:42 pm -
1 stop24h 01m
Mon 10/59:03 pm -
2 stops38h 49m
Deal found 9/4![Multiple Airlines logo]()
$279
This Kiwi.com deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/112:45 pm -
1 stop25h 01m
Sun 11/159:07 pm -
2 stops20h 28m
Deal found 9/4![Multiple Airlines logo]()
$300
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/279:56 pm -
1 stop16h 47m
Thu 10/110:47 pm -
1 stop10h 10m
Deal found 9/6![Multiple Airlines logo]()
$306
This Kiwi.com deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/212:42 pm -
1 stop24h 38m
Mon 10/262:15 pm -
2 stops45h 37m
Deal found 9/4![Multiple Airlines logo]()
$310
This Kiwi.com deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/610:25 pm -
2 stops16h 47m
Thu 11/122:41 pm -
1 stop28h 54m
Deal found 9/4![Multiple Airlines logo]()
$311
This Kiwi.com deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/18:16 pm -
1 stop18h 27m
Mon 10/59:03 pm -
2 stops38h 49m
Deal found 9/4![Multiple Airlines logo]()
$325
This Kiwi.com deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/223:54 pm -
1 stop23h 26m
Mon 10/262:15 pm -
2 stops45h 37m
Deal found 9/4![Multiple Airlines logo]()
$343
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/87:32 pm -
1 stop19h 48m
Thu 10/159:02 pm -
1 stop11h 55m
Deal found 9/8![Multiple Airlines logo]()
$357
This Kiwi.com deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/81:00 pm -
1 stop26h 46m
Thu 11/122:41 pm -
1 stop28h 54m
Deal found 9/4![Multiple Airlines logo]()
$358
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/12:46 pm -
1 stop7h 55m
Tue 10/61:34 pm -
1 stop5h 26m
Deal found 9/8![Delta logo]()
$369
Best flights from Des Moines to San JoseDiscover carefully curated flight deals from Des Moines to San Jose that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 9, 2026.
Discover carefully curated flight deals from Des Moines to San Jose that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 9, 2026.
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/12:46 pm -
1 stop7h 55m
Tue 10/61:34 pm -
1 stop5h 26m
Deal found 9/8![Delta logo]()
$369
This Southwest deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/216:35 pm -
1 stop5h 30m
Wed 10/288:05 am -
1 stop7h 45m
Deal found 9/6![Southwest logo]()
$417
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/225:06 am -
1 stop9h 03m
Mon 10/266:00 am -
1 stop5h 49m
Deal found 9/5![American Airlines logo]()
$443
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:55 am -
2 stops9h 18m
Sat 10/316:20 am -
1 stop6h 05m
Deal found 9/9![Delta logo]()
$374
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/122:59 pm -
1 stop9h 13m
Mon 11/167:00 am -
2 stops12h 13m
Deal found 9/8![Delta logo]()
$374
This Southwest deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/131:50 pm -
2 stops7h 05m
Wed 11/1811:10 am -
1 stop8h 50m
Deal found 9/6![Southwest logo]()
$435
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:55 am -
2 stops12h 07m
Mon 10/268:32 pm -
2 stops11h 39m
Deal found 9/8![Delta logo]()
$380
This Southwest deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/175:25 am -
1 stop9h 30m
Sun 12/206:05 am -
1 stop7h 00m
Deal found 9/8![Southwest logo]()
$453
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1111:00 am -
2 stops10h 49m
Sun 11/156:20 am -
1 stop5h 48m
Deal found 9/8![Delta logo]()
$438
This Delta deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/216:55 am -
2 stops9h 02m
Wed 10/286:20 am -
2 stops8h 35m
Deal found 9/6![Delta logo]()
$447
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/153:46 pm -
1 stop7h 08m
Mon 10/198:32 pm -
2 stops11h 39m
Deal found 9/8![Delta logo]()
$449
Last-minute flights from Des Moines to San JoseDiscover last-minute flight deals from Des Moines to San Jose. Data last updated September 9, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to San Jose. Data last updated September 9, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/279:56 pm -
1 stop16h 47m
Thu 10/110:47 pm -
1 stop10h 10m
Deal found 9/6![Multiple Airlines logo]()
$306
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/12:46 pm -
1 stop7h 55m
Mon 10/510:50 pm -
1 stop9h 52m
Deal found 9/9![Delta logo]()
$369
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/15:39 pm -
1 stop6h 52m
Mon 10/54:11 pm -
1 stop5h 34m
Deal found 9/8![American Airlines logo]()
$420
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/87:32 pm -
1 stop19h 48m
Thu 10/159:02 pm -
1 stop11h 55m
Deal found 9/8![Multiple Airlines logo]()
$357
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/86:55 am -
2 stops12h 07m
Thu 10/158:32 pm -
2 stops11h 39m
Deal found 9/8![Delta logo]()
$380
This Southwest deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/216:35 pm -
1 stop5h 30m
Wed 10/288:05 am -
1 stop7h 45m
Deal found 9/6![Southwest logo]()
$417
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/223:54 pm -
1 stop23h 26m
Thu 10/292:41 pm -
1 stop6h 09m
Deal found 9/7![Multiple Airlines logo]()
$398
One-way flights from Des Moines to San JoseSearch for one-way flight options from Des Moines to San Jose. Find affordable one-way fares based on user searches. Data last updated September 9, 2026.
Search for one-way flight options from Des Moines to San Jose. Find affordable one-way fares based on user searches. Data last updated September 9, 2026.
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/24:14 pm -
1 stop7h 47m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![American Airlines logo]()
$222
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/27:00 am -
2 stops10h 44m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Delta logo]()
$227
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/248:00 am -
2 stops30h 43m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![Multiple Airlines logo]()
$276
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/119:18 pm -
3 stops41h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Multiple Airlines logo]()
$284
This Southwest deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/242:25 pm -
1 stop6h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![Southwest logo]()
$299
This Delta deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/222:46 pm -
1 stop7h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![Delta logo]()
$309
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/211:47 am -
3 stops58h 06m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Multiple Airlines logo]()
$461
Find flight deals from Des Moines to San Jose
Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to San Jose (SJC). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 9, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $279 (Kiwi.com) |
One-way from | $222 (American Airlines) |
Popular in | April |
Cheapest in | February |
Average price | $511 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to San Jose that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 9, 2026.
Use the filters below to find and compare flights from Des Moines to San Jose that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesSan Jose
DSM Des Moines - SJC San Jose
DSMSJC
Des Moines
Fri 12/11
6:40 am-12:05 pm
1 stop7h 25m
San Jose
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$222
Des MoinesSan Jose
DSM Des Moines - SJC San Jose
DSMSJC
Des Moines
Fri 12/11
9:18 pm-12:53 pm
3 stops41h 35m
San Jose
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$284
Quickest round-trip
Des MoinesSan Jose
DSM Des Moines - SJC San Jose
DSMSJC
Des Moines
Thu 9/24
2:25 pm-7:20 pm
1 stop6h 55m
San Jose
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$299
Des MoinesSan Jose
DSM Des Moines - SJC San Jose
DSMSJC
Des Moines
Tue 9/22
2:46 pm-8:41 pm
1 stop7h 55m
San Jose
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$309
Des MoinesSan Jose
DSM Des Moines - SJC San Jose
DSMSJC
Des Moines
Thu 10/1
2:46 pm-8:41 pm
1 stop7h 55m
San Jose
Tue 10/6
1:34 pm-9:00 pm
1 stop5h 26m
$369
Des MoinesSan Jose
DSM Des Moines - SJC San Jose
DSMSJC
Des Moines
Sat 10/24
6:55 am-2:13 pm
2 stops9h 18m
San Jose
Sat 10/31
6:20 am-2:25 pm
1 stop6h 05m
$374
Des MoinesSan Jose
DSM Des Moines - SJC San Jose
DSMSJC
Des Moines
Thu 11/12
2:59 pm-10:12 pm
1 stop9h 13m
San Jose
Mon 11/16
7:00 am-9:13 pm
2 stops12h 13m
$374
Des MoinesSan Jose
DSM Des Moines - SJC San Jose
DSMSJC
Des Moines
Thu 10/22
6:55 am-5:02 pm
2 stops12h 07m
San Jose
Mon 10/26
8:32 pm-10:11 am
2 stops11h 39m
$380
Des MoinesSan Jose
DSM Des Moines - SJC San Jose
DSMSJC
Des Moines
Wed 10/21
6:35 pm-10:05 pm
1 stop5h 30m
San Jose
Wed 10/28
8:05 am-5:50 pm
1 stop7h 45m
$417
Des MoinesSan Jose
DSM Des Moines - SJC San Jose
DSMSJC
Des Moines
Fri 11/13
1:50 pm-6:55 pm
2 stops7h 05m
San Jose
Wed 11/18
11:10 am-10:00 pm
1 stop8h 50m
$435
Showing 1-10 of 15 resultsSorted by cheapest first
Compare providers for flights from Des Moines to San Jose
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to San Jose in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Des Moines-San Jose, California flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-San Jose, California flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-San Jose, California flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Des Moines-San Jose, California flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-San Jose, California flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Des Moines to San Jose
Have a flexible travel schedule? Discover the best time to fly to San Jose from Des Moines with our price prediction graph.
DSM-SJC
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to San Jose
What is the cheapest month to book a flight from Des Moines to San Jose, California?
Currently, February is the cheapest month in which you can book a flight from Des Moines to San Jose, California (average of $367). Flying from Des Moines to San Jose, California in April is currently the most expensive (average of $916). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Des Moines to San Jose, California?
Airfare is below average for this route at the moment.
Des Moines to San Jose, California flights typically cost between $472 and $731 in September.The cheapest round-trip price found within the last 5 days was $306 on Multiple Airlines (Sep 27-Oct 1).
Reviews of airlines servicing San Jose
Get insights into the airlines that provide service to San Jose. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Jose. Reviews last updated September 9, 2026.
Get a feel of what it's like to fly with Southwest,United Airlines, andAmerican Airlines from Des Moines to San Jose by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.0
Boarding
8.1
Crew
8.6
Comfort
8.0
Entertainment
7.5
Overall
8.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Food
7.0
Boarding
8.1
Crew
8.6
Comfort
8.0
Entertainment
7.5
Overall
8.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Food
7.0
Boarding
8.1
Crew
8.6
Comfort
8.0
Entertainment
7.5
Overall
8.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Food
7.0
Boarding
8.1
Crew
8.6
Comfort
8.0
Entertainment
7.5
Overall
8.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Related info for your journey
Find useful and relevant information for your journey from Des Moines to San Jose. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Des Moines to San Jose
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Complete your trip
Complete your trip to San Jose by adding a car rental and/or hotel reservation to your travel itinerary.
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Find flights from Des Moines to San Jose, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Des Moines and San Jose flights
Browse other Des Moines and San Jose flight options. Last updated on September 9, 2026.
Other flights from Des Moines
Browse through other flights departing from Des Moines. Flights are based on user searches made on Cheapflights and were last updated on September 9, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to San Jose
Explore flights to San Jose departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 9, 2026.
Top 3 airlines flying from Des Moines to San Jose
Discover the top 3 airlines that operate flights from Des Moines to San Jose. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 9, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$355 | Average$510 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$364 | Average$609 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$368 | Average$536 | FlexibilityNo cancel fee | On-time63% |