$84+ Cheap flights from Des Moines to San Diego (DSM - SAN)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/10. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — SAN
Jul 7 — Jul 141
Round-trip
1 adult, Economy
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Find cheap flights from Des Moines to San Diego with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Des Moines to San Diego are usually found in August or September, booked 36 days in advance, depart on a Monday or Tuesday and return on a Wednesday
Cheap flight deals from Des Moines to San Diego
Cheapest
Best
Last-minute
One-way
Cheapest flights from Des Moines to San DiegoExplore the most affordable flight options available from Des Moines to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 7, 2026.
Explore the most affordable flight options available from Des Moines to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 7, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1010:06 pm
DSM
- SAN
1 stop18h 02m
Multiple Airlines
Wed 8/199:53 pm
SAN
- DSM
1 stop21h 07m
Multiple Airlines
Deal found 6/7![Multiple Airlines logo]()
$179
This Kiwi.com deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/2010:01 pm
DSM
- SAN
1 stop18h 07m
Multiple Airlines
Tue 7/283:03 pm
SAN
- DSM
1 stop19h 56m
Multiple Airlines
Deal found 6/6![Multiple Airlines logo]()
$209
This Kiwi.com deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/2010:01 pm
DSM
- SAN
1 stop18h 07m
Multiple Airlines
Mon 7/274:12 pm
SAN
- DSM
2 stops42h 47m
Multiple Airlines
Deal found 6/5![Multiple Airlines logo]()
$216
This Kiwi.com deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/199:33 pm
DSM
- SAN
1 stop24h 33m
Multiple Airlines
Tue 7/283:03 pm
SAN
- DSM
1 stop19h 56m
Multiple Airlines
Deal found 6/2![Multiple Airlines logo]()
$235
This Kiwi.com deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/2410:01 pm
DSM
- SAN
1 stop24h 05m
Multiple Airlines
Tue 7/284:12 pm
SAN
- DSM
2 stops18h 47m
Multiple Airlines
Deal found 6/3![Multiple Airlines logo]()
$240
This Expedia deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/152:19 pm
DSM
- SAN
1 stop11h 32m
Frontier
Wed 7/226:25 am
SAN
- DSM
1 stop5h 09m
Frontier
Deal found 6/2![Frontier logo]()
$248
This Kiwi.com deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/2010:01 pm
DSM
- SAN
1 stop18h 07m
Multiple Airlines
Thu 7/306:25 am
SAN
- DSM
1 stop29h 09m
Multiple Airlines
Deal found 6/2![Multiple Airlines logo]()
$255
This Kiwi.com deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/159:56 pm
DSM
- SAN
1 stop12h 52m
Multiple Airlines
Tue 6/239:43 am
SAN
- DSM
2 stops25h 48m
Multiple Airlines
Deal found 6/2![Multiple Airlines logo]()
$260
Best flights from Des Moines to San DiegoDiscover carefully curated flight deals from Des Moines to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 7, 2026.
Discover carefully curated flight deals from Des Moines to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 7, 2026.
This United Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/306:20 am
DSM
- SAN
1 stop6h 31m
United Airlines
Wed 7/86:20 am
SAN
- DSM
2 stops7h 55m
United Airlines
Deal found 6/4![United Airlines logo]()
$372
This Southwest deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/307:15 am
DSM
- SAN
2 stops7h 15m
Southwest
Mon 10/52:30 pm
SAN
- DSM
1 stop6h 05m
Southwest
Deal found 6/6![Southwest logo]()
$422
This United Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/225:45 am
DSM
- SAN
1 stop5h 20m
United Airlines
Tue 9/296:20 am
SAN
- DSM
2 stops7h 56m
United Airlines
Deal found 6/4![United Airlines logo]()
$372
This Southwest deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/283:45 pm
DSM
- SAN
1 stop9h 40m
Southwest
Sun 8/23:40 pm
SAN
- DSM
1 stop6h 10m
Southwest
Deal found 6/5![Southwest logo]()
$427
This United Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/145:45 am
DSM
- SAN
1 stop5h 20m
United Airlines
Tue 9/294:11 pm
SAN
- DSM
1 stop5h 46m
United Airlines
Deal found 6/4![United Airlines logo]()
$390
This Southwest deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/295:35 am
DSM
- SAN
2 stops11h 45m
Southwest
Sun 11/110:40 pm
SAN
- DSM
1 stop10h 50m
Southwest
Deal found 6/2![Southwest logo]()
$446
This United Airlines deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/115:17 pm
DSM
- SAN
2 stops8h 37m
United Airlines
Tue 7/1412:33 pm
SAN
- DSM
1 stop5h 57m
United Airlines
Deal found 6/3![United Airlines logo]()
$412
This Southwest deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/156:25 am
DSM
- SAN
2 stops8h 45m
Southwest
Wed 7/227:50 am
SAN
- DSM
2 stops8h 30m
Southwest
Deal found 6/2![Southwest logo]()
$447
This United Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1011:33 am
DSM
- SAN
2 stops7h 53m
United Airlines
Mon 9/2812:37 pm
SAN
- DSM
1 stop6h 23m
United Airlines
Deal found 6/4![United Airlines logo]()
$418
This Southwest deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/215:20 am
DSM
- SAN
2 stops10h 35m
Southwest
Fri 11/278:15 am
SAN
- DSM
1 stop5h 35m
Southwest
Deal found 6/2![Southwest logo]()
$452
This United Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/299:09 am
DSM
- SAN
1 stop5h 29m
United Airlines
Sun 11/17:00 am
SAN
- DSM
1 stop7h 14m
United Airlines
Deal found 6/5![United Airlines logo]()
$430
This Southwest deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/283:45 pm
DSM
- SAN
1 stop9h 40m
Southwest
Sat 8/111:30 am
SAN
- DSM
2 stops8h 30m
Southwest
Deal found 6/5![Southwest logo]()
$465
Last-minute flights from Des Moines to San DiegoDiscover last-minute flight deals from Des Moines to San Diego. Data last updated June 7, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to San Diego. Data last updated June 7, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/159:56 pm
DSM
- SAN
1 stop12h 52m
Multiple Airlines
Tue 6/239:43 am
SAN
- DSM
2 stops25h 48m
Multiple Airlines
Deal found 6/2![Multiple Airlines logo]()
$260
This Expedia deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/152:19 pm
DSM
- SAN
1 stop11h 32m
Frontier
Wed 7/226:25 am
SAN
- DSM
1 stop5h 09m
Frontier
Deal found 6/2![Frontier logo]()
$248
This Kiwi.com deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/199:33 pm
DSM
- SAN
1 stop24h 33m
Multiple Airlines
Tue 7/283:03 pm
SAN
- DSM
1 stop19h 56m
Multiple Airlines
Deal found 6/2![Multiple Airlines logo]()
$235
This Kiwi.com deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/2010:01 pm
DSM
- SAN
1 stop18h 07m
Multiple Airlines
Tue 7/283:03 pm
SAN
- DSM
1 stop19h 56m
Multiple Airlines
Deal found 6/6![Multiple Airlines logo]()
$209
This Kiwi.com deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/2010:01 pm
DSM
- SAN
1 stop18h 07m
Multiple Airlines
Mon 7/274:12 pm
SAN
- DSM
2 stops42h 47m
Multiple Airlines
Deal found 6/5![Multiple Airlines logo]()
$216
This Kiwi.com deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/2010:01 pm
DSM
- SAN
1 stop18h 07m
Multiple Airlines
Thu 7/306:25 am
SAN
- DSM
1 stop29h 09m
Multiple Airlines
Deal found 6/2![Multiple Airlines logo]()
$255
This Frontier deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/222:19 pm
DSM
- SAN
1 stop11h 32m
Frontier
Fri 7/246:25 am
SAN
- DSM
1 stop5h 09m
Frontier
Deal found 6/2![Frontier logo]()
$268
This Kiwi.com deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/2410:01 pm
DSM
- SAN
1 stop24h 05m
Multiple Airlines
Tue 7/284:12 pm
SAN
- DSM
2 stops18h 47m
Multiple Airlines
Deal found 6/3![Multiple Airlines logo]()
$240
One-way flights from Des Moines to San DiegoSearch for one-way flight options from Des Moines to San Diego. Find affordable one-way fares based on user searches. Data last updated June 7, 2026.
Search for one-way flight options from Des Moines to San Diego. Find affordable one-way fares based on user searches. Data last updated June 7, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1010:06 pm
DSM
- SAN
1 stop18h 02m
Multiple Airlines
Deal found 6/4![Multiple Airlines logo]()
$84
This Kiwi.com deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/1310:01 pm
DSM
- SAN
1 stop18h 07m
Multiple Airlines
Deal found 6/6![Multiple Airlines logo]()
$90
This Kiwi.com deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/310:01 pm
DSM
- SAN
1 stop18h 07m
Multiple Airlines
Deal found 6/5![Multiple Airlines logo]()
$91
This Kiwi.com deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/299:56 pm
DSM
- SAN
1 stop12h 52m
Multiple Airlines
Deal found 6/4![Multiple Airlines logo]()
$106
This Mytrip deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/222:19 pm
DSM
- SAN
1 stop11h 32m
Frontier
Deal found 6/7![Frontier logo]()
$129
This Kiwi.com deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/229:56 pm
DSM
- SAN
1 stop12h 52m
Multiple Airlines
Deal found 6/3![Multiple Airlines logo]()
$142
This Flightnetwork deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flightnetwork is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/82:19 pm
DSM
- SAN
1 stop11h 32m
Frontier
Deal found 6/6![Frontier logo]()
$168
This United Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/95:21 pm
DSM
- SAN
1 stop5h 13m
United Airlines
Deal found 6/5![United Airlines logo]()
$184
Find flight deals from Des Moines to San Diego
Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 7, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $179 (Kiwi.com) |
One-way from | $84 (Kiwi.com) |
Popular in | March |
Cheapest in | August |
Average price | $367 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 7, 2026.
Use the filters below to find and compare flights from Des Moines to San Diego that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesSan Diego
DSM - SAN
DSMSAN
Des Moines
Tue 6/30
6:20 am-10:51 am
1 stop6h 31m
San Diego
Wed 7/8
6:20 am-4:15 pm
2 stops7h 55m
$372
Des MoinesSan Diego
DSM - SAN
DSMSAN
Des Moines
Tue 9/22
5:45 am-9:05 am
1 stop5h 20m
San Diego
Tue 9/29
6:20 am-4:16 pm
2 stops7h 56m
$372
Quickest round-trip
Des MoinesSan Diego
DSM - SAN
DSMSAN
Des Moines
Mon 9/14
5:45 am-9:05 am
1 stop5h 20m
San Diego
Tue 9/29
4:11 pm-11:57 pm
1 stop5h 46m
$390
Des MoinesSan Diego
DSM - SAN
DSMSAN
Des Moines
Sat 7/11
5:17 pm-11:54 pm
2 stops8h 37m
San Diego
Tue 7/14
12:33 pm-8:30 pm
1 stop5h 57m
$412
Des MoinesSan Diego
DSM - SAN
DSMSAN
Des Moines
Thu 9/10
11:33 am-5:26 pm
2 stops7h 53m
San Diego
Mon 9/28
12:37 pm-9:00 pm
1 stop6h 23m
$418
Des MoinesSan Diego
DSM - SAN
DSMSAN
Des Moines
Wed 9/30
7:15 am-12:30 pm
2 stops7h 15m
San Diego
Mon 10/5
2:30 pm-10:35 pm
1 stop6h 05m
$422
Des MoinesSan Diego
DSM - SAN
DSMSAN
Des Moines
Tue 7/28
3:45 pm-11:25 pm
1 stop9h 40m
San Diego
Sun 8/2
3:40 pm-11:50 pm
1 stop6h 10m
$427
Des MoinesSan Diego
DSM - SAN
DSMSAN
Des Moines
Thu 10/29
9:09 am-12:38 pm
1 stop5h 29m
San Diego
Sun 11/1
7:00 am-4:14 pm
1 stop7h 14m
$430
Des MoinesSan Diego
DSM - SAN
DSMSAN
Des Moines
Thu 10/29
5:35 am-3:20 pm
2 stops11h 45m
San Diego
Sun 11/1
10:40 pm-11:30 am
1 stop10h 50m
$446
Des MoinesSan Diego
DSM - SAN
DSMSAN
Des Moines
Wed 7/15
6:25 am-1:10 pm
2 stops8h 45m
San Diego
Wed 7/22
7:50 am-6:20 pm
2 stops8h 30m
$447
Showing 1-10 of 21 resultsSorted by cheapest first
Compare providers for flights from Des Moines to San Diego
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to San Diego in June.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star |
- Most accurate provider: When it comes to deals on Des Moines-San Diego flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-San Diego flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-San Diego flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Des Moines-San Diego flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-San Diego flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Des Moines to San Diego
Have a flexible travel schedule? Discover the best time to fly to San Diego from Des Moines with our price prediction graph.
DSM-SAN
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to San Diego
How far ahead should I book a flight from Des Moines to San Diego?
The price you pay for your flight from Des Moines to San Diego may vary depending on when you book. For the best chance of a lower fare, look to book 8 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Des Moines to San Diego?
Currently, August is the cheapest month in which you can book a flight from Des Moines to San Diego (average of $203). Flying from Des Moines to San Diego in March is currently the most expensive (average of $576). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Des Moines to San Diego?
Reviews of airlines servicing San Diego
Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated June 7, 2026.
Read through reviews of airlines operating flights from Des Moines to San Diego, such as Southwest,United Airlines, andAllegiant Air. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.6
Comfort
8.0
Food
7.0
Entertainment
7.5
Boarding
8.1
Overall
7.9
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Crew
8.6
Comfort
8.0
Food
7.0
Entertainment
7.5
Boarding
8.1
Overall
7.9
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Crew
8.6
Comfort
8.0
Food
7.0
Entertainment
7.5
Boarding
8.1
Overall
7.9
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Crew
8.6
Comfort
8.0
Food
7.0
Entertainment
7.5
Boarding
8.1
Overall
7.9
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Crew
8.6
Comfort
8.0
Food
7.0
Entertainment
7.5
Boarding
8.1
Overall
7.9
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Crew
8.6
Comfort
8.0
Food
7.0
Entertainment
7.5
Boarding
8.1
Overall
7.9
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Related info for your journey
Find useful and relevant information for your journey from Des Moines to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Top 6 airlines flying from Des Moines to San Diego
Discover the top 6 airlines that operate flights from Des Moines to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 7, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$100 | Average$238 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$102 | Average$154 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$118 | Average$333 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$286 | Average$405 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$303 | Average$474 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$310 | Average$410 | FlexibilityNo cancel fee | On-time69% |