$359+ Cheap flights from Des Moines to San Luis Obispo (DSM - SBP)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/24. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — SBP
Oct 13 — Oct 201
Round-trip
1 adult, Economy
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Find cheap flights from Des Moines to San Luis Obispo with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Des Moines to San Luis Obispo
Cheapest
Best
Last-minute
Cheapest flights from Des Moines to San Luis ObispoExplore the most affordable flight options available from Des Moines to San Luis Obispo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 13, 2026.
Explore the most affordable flight options available from Des Moines to San Luis Obispo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 13, 2026.
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:14 am -
1 stop7h 34m
Fri 11/612:42 pm -
1 stop5h 36m
Deal found 9/11![American Airlines logo]()
$359
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/249:15 am -
1 stop6h 04m
Fri 11/610:38 am -
2 stops9h 17m
Deal found 9/11![United Airlines logo]()
$364
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/252:17 pm -
1 stop6h 17m
Fri 10/212:31 pm -
1 stop8h 41m
Deal found 9/10![American Airlines logo]()
$394
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:29 pm -
1 stop6h 30m
Sun 10/186:00 am -
1 stop5h 49m
Deal found 9/8![American Airlines logo]()
$446
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/145:09 pm -
1 stop6h 01m
Wed 11/1812:54 pm -
1 stop5h 42m
Deal found 9/10![United Airlines logo]()
$459
Best flights from Des Moines to San Luis ObispoDiscover carefully curated flight deals from Des Moines to San Luis Obispo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 13, 2026.
Discover carefully curated flight deals from Des Moines to San Luis Obispo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 13, 2026.
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:14 am -
1 stop7h 34m
Fri 11/612:42 pm -
1 stop5h 36m
Deal found 9/11![American Airlines logo]()
$359
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/249:15 am -
1 stop6h 04m
Fri 11/610:38 am -
2 stops9h 17m
Deal found 9/11![United Airlines logo]()
$364
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:29 pm -
1 stop6h 30m
Sun 10/186:00 am -
1 stop5h 49m
Deal found 9/8![American Airlines logo]()
$446
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/145:12 pm -
1 stop5h 58m
Wed 11/1812:54 pm -
1 stop5h 42m
Deal found 9/9![United Airlines logo]()
$459
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/65:00 am -
1 stop9h 09m
Wed 3/104:34 pm -
1 stop5h 23m
Deal found 9/8![American Airlines logo]()
$466
Last-minute flights from Des Moines to San Luis ObispoDiscover last-minute flight deals from Des Moines to San Luis Obispo. Data last updated September 13, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to San Luis Obispo. Data last updated September 13, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/252:17 pm -
1 stop6h 17m
Fri 10/212:31 pm -
1 stop8h 41m
Deal found 9/10![American Airlines logo]()
$394
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/255:45 am -
2 stops8h 17m
Fri 10/27:11 am -
2 stops13h 04m
Deal found 9/11![United Airlines logo]()
$504
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:29 pm -
1 stop6h 30m
Sun 10/186:00 am -
1 stop5h 49m
Deal found 9/8![American Airlines logo]()
$446
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:14 am -
1 stop7h 34m
Fri 11/612:42 pm -
1 stop5h 36m
Deal found 9/11![American Airlines logo]()
$359
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/249:15 am -
1 stop6h 04m
Fri 11/610:38 am -
2 stops9h 17m
Deal found 9/11![United Airlines logo]()
$364
Find flight deals from Des Moines to San Luis Obispo
Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to San Luis Obispo (SBP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 13, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $359 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to San Luis Obispo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 13, 2026.
Use the filters below to find and compare flights from Des Moines to San Luis Obispo that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesSan Luis Obispo
DSM Des Moines - SBP San Luis Obispo County
DSMSBP
Des Moines
Sat 10/24
6:14 am-11:48 am
1 stop7h 34m
San Luis Obispo County
Fri 11/6
12:42 pm-8:18 pm
1 stop5h 36m
$359
Des MoinesSan Luis Obispo
DSM Des Moines - SBP San Luis Obispo County
DSMSBP
Des Moines
Sat 10/24
9:15 am-1:19 pm
1 stop6h 04m
San Luis Obispo County
Fri 11/6
10:38 am-9:55 pm
2 stops9h 17m
$364
Des MoinesSan Luis Obispo
DSM Des Moines - SBP San Luis Obispo County
DSMSBP
Des Moines
Wed 10/14
6:29 pm-10:59 pm
1 stop6h 30m
San Luis Obispo County
Sun 10/18
6:00 am-1:49 pm
1 stop5h 49m
$446
Quickest round-trip
Des MoinesSan Luis Obispo
DSM Des Moines - SBP San Luis Obispo County
DSMSBP
Des Moines
Sat 11/14
5:12 pm-9:10 pm
1 stop5h 58m
San Luis Obispo County
Wed 11/18
12:54 pm-8:36 pm
1 stop5h 42m
$459
Des MoinesSan Luis Obispo
DSM Des Moines - SBP San Luis Obispo County
DSMSBP
Des Moines
Sat 3/6
5:00 am-12:09 pm
1 stop9h 09m
San Luis Obispo County
Wed 3/10
4:34 pm-11:57 pm
1 stop5h 23m
$466
Sorted by cheapest first
Compare providers for flights from Des Moines to San Luis Obispo
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to San Luis Obispo in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Des Moines-San Luis Obispo flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-San Luis Obispo flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-San Luis Obispo flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Des Moines-San Luis Obispo flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-San Luis Obispo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Des Moines to San Luis Obispo
Have a flexible travel schedule? Discover the best time to fly to San Luis Obispo from Des Moines with our price prediction graph.
DSM-SBP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing San Luis Obispo
Get insights into the airlines that provide service to San Luis Obispo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Luis Obispo. Reviews last updated September 13, 2026.
Get a feel of what it's like to fly with American Airlines from Des Moines to San Luis Obispo by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
7.4
Food
6.4
Comfort
7.2
Entertainment
6.8
Overall
7.1
Crew
7.9
Reviews
1 / 20
2.0
MediocreAnonymous,Mar 2026
MIA - SFO
Boarding
7.4
Food
6.4
Comfort
7.2
Entertainment
6.8
Overall
7.1
Crew
7.9
Reviews
1 / 20
2.0
MediocreAnonymous,Mar 2026
MIA - SFO
Related info for your journey
Find useful and relevant information for your journey from Des Moines to San Luis Obispo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Luis Obispo?
Book flights to San Luis Obispo if you plan to visit one of these locationsCambria
Morro Bay
Arroyo Grande
San Simeon
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Alternative routes for Des Moines to San Luis Obispo
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Complete your trip
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Des Moines and San Luis Obispo flights
Browse other Des Moines and San Luis Obispo flight options. Last updated on September 13, 2026.
Other flights from Des Moines
Browse through other flights departing from Des Moines. Flights are based on user searches made on Cheapflights and were last updated on September 13, 2026.
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Other flights to San Luis Obispo
Explore flights to San Luis Obispo departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 13, 2026.
Top airline flying from Des Moines to San Luis Obispo
Discover the top airline that operate flights from Des Moines to San Luis Obispo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 13, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$288 | Average$483 | FlexibilityNo cancel fee | On-time71% |