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San Luis Obispo

$369+ Cheap flights from Des Moines to San Luis Obispo (DSM - SBP)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/18. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — SBP
May 29 — Jun 51
Fri 5/29
Fri 6/5
1 adult, Economy
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Cheap flight deals from Des Moines to San Luis Obispo

Cheapest flights from Des Moines to San Luis Obispo
Explore the most affordable flight options available from Des Moines to San Luis Obispo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 29, 2026.

This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/182:26 pm
DSM
-
SBP
1 stop6h 05m
American Airlines
Sat 7/254:07 pm
SBP
-
DSM
1 stop5h 41m
American Airlines
Deal found 4/27$369
This United Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/241:35 pm
DSM
-
SBP
2 stops8h 27m
United Airlines
Sat 10/317:45 am
SBP
-
DSM
2 stops10h 47m
United Airlines
Deal found 4/24$379
This American Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:30 am
DSM
-
SBP
1 stop7h 15m
American Airlines
Sat 10/311:10 pm
SBP
-
DSM
1 stop8h 39m
American Airlines
Deal found 4/24$394
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/55:10 am
DSM
-
SBP
1 stop9h 02m
American Airlines
Sun 11/84:18 pm
SBP
-
DSM
1 stop5h 41m
American Airlines
Deal found 4/29$436
This American Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/95:30 am
DSM
-
SBP
1 stop8h 31m
American Airlines
Tue 6/1612:51 pm
SBP
-
DSM
1 stop8h 01m
American Airlines
Deal found 4/24$440
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/146:26 pm
DSM
-
SBP
1 stop5h 44m
American Airlines
Tue 5/196:06 am
SBP
-
DSM
1 stop5h 41m
American Airlines
Deal found 4/27$469

Find flight deals from Des Moines to San Luis Obispo

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to San Luis Obispo (SBP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$369
(American Airlines)
Provider with most accurate pricing for Des Moines-San Luis Obispo County flight deals.
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Provider most trusted by Cheapflights users for Des Moines-San Luis Obispo County flights.
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From Des Moines to San Luis Obispo County
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to San Luis Obispo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2026.
Use the filters below to find and compare flights from Des Moines to San Luis Obispo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

Des MoinesSan Luis Obispo

DSM - SBP

DSMSBP

Des Moines

Sat 7/18

2:26 pm-6:31 pm

1 stop6h 05m

San Luis Obispo County

Sat 7/25

4:07 pm-11:48 pm

1 stop5h 41m

$369

Des MoinesSan Luis Obispo

DSM - SBP

DSMSBP

Des Moines

Sat 10/24

1:35 pm-8:02 pm

2 stops8h 27m

San Luis Obispo County

Sat 10/31

7:45 am-8:32 pm

2 stops10h 47m

$379

Des MoinesSan Luis Obispo

DSM - SBP

DSMSBP

Des Moines

Sat 10/24

6:30 am-11:45 am

1 stop7h 15m

San Luis Obispo County

Sat 10/31

1:10 pm-11:49 pm

1 stop8h 39m

$394

Des MoinesSan Luis Obispo

DSM - SBP

DSMSBP

Des Moines

Tue 6/9

5:30 am-11:47 am

2 stops8h 17m

San Luis Obispo County

Tue 6/16

6:52 pm-9:11 am

2 stops12h 19m

$451

Des MoinesSan Luis Obispo

DSM - SBP

DSMSBP

Des Moines

Thu 5/14

6:26 pm-10:10 pm

1 stop5h 44m

San Luis Obispo County

Tue 5/19

12:55 pm-11:16 pm

1 stop8h 21m

$469

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/27

Sorted by cheapest first

Compare providers for flights from Des Moines to San Luis Obispo

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to San Luis Obispo in April.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Des Moines-San Luis Obispo flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-San Luis Obispo flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-San Luis Obispo flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Des Moines-San Luis Obispo flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-San Luis Obispo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to San Luis Obispo

Have a flexible travel schedule? Discover the best time to fly to San Luis Obispo from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing San Luis Obispo

Get insights into the airlines that provide service to San Luis Obispo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Luis Obispo. Reviews last updated April 29, 2026.
Get a feel of what it's like to fly with American Airlines from Des Moines to San Luis Obispo by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.1
Good
11,678 reviews

Entertainment

6.9

Overall

7.1

Crew

7.9

Food

6.4

Boarding

7.5

Comfort

7.2

Reviews

1 / 20
2.0
Mediocre

Anonymous,Mar 2026

MIA - SFO

Horrible. When they power flights for other airlines there is nothing they can do to change or accommodate any changes
American Airlines
7.1
Good
11,678 reviews
American Airlines
7.1
Good
11,678 reviews

Entertainment

6.9

Overall

7.1

Crew

7.9

Food

6.4

Boarding

7.5

Comfort

7.2

Reviews

1 / 20
2.0
Mediocre

Anonymous,Mar 2026

MIA - SFO

Horrible. When they power flights for other airlines there is nothing they can do to change or accommodate any changes

Related info for your journey

Find useful and relevant information for your journey from Des Moines to San Luis Obispo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Des Moines to San Luis Obispo?

    There are many flights that can get you from Des Moines to San Luis Obispo in 6h 05m. Fly via American Airlines or United Airlines to get the fastest option. Airlines will cover a distance of 1517 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What is the cheapest airline to fly from Des Moines to San Luis Obispo round-trip?

    Flying on American Airlines is currently your cheapest option to San Luis Obispo, with prices starting at $243.

  • Can I find deals for flights from Des Moines to San Luis Obispo that include hotel bookings?

    Yes. In addition to deals on Des Moines to San Luis Obispo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to San Luis Obispo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to San Luis Obispo.

  • Can I find deals for business class flights from Des Moines to San Luis Obispo?

    Yes. Cheapflights offers flight deals from Des Moines to San Luis Obispo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near San Luis Obispo?

Book flights to San Luis Obispo if you plan to visit one of these locations
Morro Bay
Cambria
Arroyo Grande
San Simeon

Browse thousands of different options on Cheapflights for your next trip

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Top airline flying from Des Moines to San Luis Obispo

Discover the top airline that operate flights from Des Moines to San Luis Obispo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$243Average$313FlexibilityNo cancel feeOn-time71%

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