$89+ Cheap flights from Des Moines to Boston (DSM - BOS)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/2. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — BOS
Oct 10 — Oct 171
Round-trip
1 adult, Economy
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Find cheap flights from Des Moines to Boston with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Des Moines to Boston Logan Intl are usually found in May or April, booked 42 days in advance, depart on a Monday or Wednesday and return on a Friday
Cheap flight deals from Des Moines to Boston
Cheapest
Best
Last-minute
One-way
Cheapest flights from Des Moines to BostonExplore the most affordable flight options available from Des Moines to Boston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 10, 2026.
Explore the most affordable flight options available from Des Moines to Boston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 10, 2026.
This CheapOair deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/27:20 am -
Nonstop2h 49m
Fri 11/612:11 pm -
Nonstop3h 10m
Deal found 9/8![Allegiant Air logo]()
$89
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/27:20 am -
Nonstop2h 49m
Fri 11/1312:11 pm -
Nonstop3h 10m
Deal found 9/8![Allegiant Air logo]()
$113
This CheapOair deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/197:15 am -
Nonstop2h 47m
Fri 10/3012:07 pm -
Nonstop3h 07m
Deal found 9/5![Allegiant Air logo]()
$136
This CheapOair deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/197:15 am -
Nonstop2h 47m
Fri 10/2312:07 pm -
Nonstop3h 07m
Deal found 9/8![Allegiant Air logo]()
$176
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/307:30 am -
Nonstop2h 47m
Fri 11/1312:11 pm -
Nonstop3h 10m
Deal found 9/8![Allegiant Air logo]()
$180
Best flights from Des Moines to BostonDiscover carefully curated flight deals from Des Moines to Boston that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 10, 2026.
Discover carefully curated flight deals from Des Moines to Boston that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 10, 2026.
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:54 pm -
1 stop5h 26m
Wed 10/215:30 am -
1 stop6h 12m
Deal found 9/8![Delta logo]()
$339
This Southwest deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/215:35 am -
2 stops10h 10m
Wed 10/287:20 am -
1 stop5h 10m
Deal found 9/6![Southwest logo]()
$408
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/126:45 pm -
1 stop5h 01m
Mon 11/169:12 am -
2 stops12h 24m
Deal found 9/9![United Airlines logo]()
$434
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/175:50 pm -
1 stop5h 09m
Wed 10/216:50 am -
1 stop8h 19m
Deal found 9/8![Delta logo]()
$339
This Southwest deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/35:50 am -
2 stops11h 30m
Tue 10/610:55 am -
2 stops10h 45m
Deal found 9/8![Southwest logo]()
$433
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/174:07 pm -
1 stop6h 27m
Sun 10/185:39 am -
1 stop5h 03m
Deal found 9/8![Delta logo]()
$408
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:55 pm -
1 stop4h 59m
Mon 10/126:00 am -
1 stop5h 31m
Deal found 9/9![United Airlines logo]()
$456
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/86:55 pm -
1 stop4h 59m
Thu 10/156:00 am -
1 stop7h 34m
Deal found 9/7![United Airlines logo]()
$479
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/186:54 pm -
1 stop5h 26m
Wed 10/219:05 am -
1 stop6h 04m
Deal found 9/8![Delta logo]()
$469
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/166:54 pm -
1 stop5h 26m
Mon 10/195:39 am -
1 stop5h 03m
Deal found 9/9![Delta logo]()
$474
Last-minute flights from Des Moines to BostonDiscover last-minute flight deals from Des Moines to Boston. Data last updated September 10, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Boston. Data last updated September 10, 2026 and is based on user searches.
This CheapOair deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/197:15 am -
Nonstop2h 47m
Fri 10/3012:07 pm -
Nonstop3h 07m
Deal found 9/5![Allegiant Air logo]()
$136
This CheapOair deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/197:15 am -
Nonstop2h 47m
Fri 10/2312:07 pm -
Nonstop3h 07m
Deal found 9/8![Allegiant Air logo]()
$176
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/197:15 am -
Nonstop2h 47m
Wed 10/2112:57 pm -
2 stops26h 45m
Deal found 9/8![Multiple Airlines logo]()
$234
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/197:15 am -
Nonstop2h 47m
Sat 10/2411:42 am -
2 stops27h 17m
Deal found 9/8![Multiple Airlines logo]()
$269
This Gotogate deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/237:30 am -
Nonstop2h 47m
Fri 10/3012:07 pm -
Nonstop3h 07m
Deal found 9/8![Allegiant Air logo]()
$291
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/238:25 pm -
2 stops37h 37m
Fri 10/3012:07 pm -
Nonstop3h 07m
Deal found 9/8![Multiple Airlines logo]()
$308
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/307:30 am -
Nonstop2h 47m
Fri 11/1312:11 pm -
Nonstop3h 10m
Deal found 9/8![Allegiant Air logo]()
$180
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/307:30 am -
Nonstop2h 47m
Mon 11/911:41 am -
Nonstop3h 10m
Deal found 9/8![Allegiant Air logo]()
$277
One-way flights from Des Moines to BostonSearch for one-way flight options from Des Moines to Boston. Find affordable one-way fares based on user searches. Data last updated September 10, 2026.
Search for one-way flight options from Des Moines to Boston. Find affordable one-way fares based on user searches. Data last updated September 10, 2026.
This CheapOair deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/167:30 am -
Nonstop2h 47m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Allegiant Air logo]()
$134
This Super.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/286:30 am -
Nonstop2h 51m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Allegiant Air logo]()
$140
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/216:30 am -
Nonstop2h 51m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Allegiant Air logo]()
$150
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:55 pm -
1 stop4h 59m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![United Airlines logo]()
$170
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/38:00 am -
2 stops8h 09m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![United Airlines logo]()
$175
This Super.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/27:35 am -
Nonstop2h 47m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Allegiant Air logo]()
$184
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/22:29 pm -
1 stop6h 58m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![American Airlines logo]()
$185
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/258:00 am -
2 stops49h 17m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Multiple Airlines logo]()
$194
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/2610:35 am -
1 stop6h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![American Airlines logo]()
$202
Find flight deals from Des Moines to Boston
Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Boston (BOS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $89 (CheapOair) |
Popular in | March |
Cheapest in | May |
Average price | $379 |
Good round-trip deal | $142 or less |
Good one-way deal | $154 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Boston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 10, 2026.
Use the filters below to find and compare flights from Des Moines to Boston that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesBoston
DSM Des Moines - BOS Boston Logan Intl
DSMBOS
Des Moines
Sat 10/3
8:00 am-5:09 pm
2 stops8h 09m
Boston Logan Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$175
Des MoinesBoston
DSM Des Moines - BOS Boston Logan Intl
DSMBOS
Des Moines
Sun 10/25
8:00 am-10:17 am
2 stops49h 17m
Boston Logan Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$194
Des MoinesBoston
DSM Des Moines - BOS Boston Logan Intl
DSMBOS
Des Moines
Fri 10/16
6:54 pm-1:20 am
1 stop5h 26m
Boston Logan Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$202
Quickest round-trip
Des MoinesBoston
DSM Des Moines - BOS Boston Logan Intl
DSMBOS
Des Moines
Wed 10/21
6:00 am-12:14 pm
1 stop5h 14m
Boston Logan Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$202
Des MoinesBoston
DSM Des Moines - BOS Boston Logan Intl
DSMBOS
Des Moines
Tue 10/6
1:27 pm-9:49 pm
1 stop7h 22m
Boston Logan Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$202
Des MoinesBoston
DSM Des Moines - BOS Boston Logan Intl
DSMBOS
Des Moines
Thu 10/29
1:27 pm-11:50 pm
1 stop9h 23m
Boston Logan Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$202
Des MoinesBoston
DSM Des Moines - BOS Boston Logan Intl
DSMBOS
Des Moines
Wed 10/21
5:35 am-4:45 pm
2 stops10h 10m
Boston Logan Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$207
Des MoinesBoston
DSM Des Moines - BOS Boston Logan Intl
DSMBOS
Des Moines
Sat 10/17
6:00 am-2:55 pm
2 stops7h 55m
Boston Logan Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$207
Des MoinesBoston
DSM Des Moines - BOS Boston Logan Intl
DSMBOS
Des Moines
Sat 9/26
1:26 pm-10:45 pm
2 stops8h 19m
Boston Logan Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$207
Des MoinesBoston
DSM Des Moines - BOS Boston Logan Intl
DSMBOS
Des Moines
Sun 10/18
6:54 pm-1:20 am
1 stop5h 26m
Boston Logan Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$239
Showing 1-10 of 21 resultsSorted by cheapest first
Compare providers for flights from Des Moines to Boston
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Boston in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star |
- Most accurate provider: When it comes to deals on Des Moines-Boston flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Boston flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Boston flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Des Moines-Boston flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Boston flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Des Moines to Boston
Have a flexible travel schedule? Discover the best time to fly to Boston from Des Moines with our price prediction graph.
DSM-BOS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Boston
How far ahead should I book a flight from Des Moines to Boston?
The price you pay for your flight from Des Moines to Boston may vary depending on when you book. For the best chance of a lower fare, look to book 41 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Des Moines to Boston?
Currently, May is the cheapest month in which you can book a flight from Des Moines to Boston (average of $194). Flying from Des Moines to Boston in March is currently the most expensive (average of $492). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from DSM to BOS?
Find hourly flight availability from Des Moines to Boston. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 10, 2026.
When flying from Des Moines to Boston, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
Reviews of airlines servicing Boston
Get insights into the airlines that provide service to Boston. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Boston. Reviews last updated September 10, 2026.
Get a feel of what it's like to fly with Southwest,Delta, andUnited Airlines from Des Moines to Boston by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Overall
8.0
Entertainment
7.5
Food
7.0
Crew
8.6
Boarding
8.1
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Comfort
8.0
Overall
8.0
Entertainment
7.5
Food
7.0
Crew
8.6
Boarding
8.1
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Comfort
8.0
Overall
8.0
Entertainment
7.5
Food
7.0
Crew
8.6
Boarding
8.1
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Comfort
8.0
Overall
8.0
Entertainment
7.5
Food
7.0
Crew
8.6
Boarding
8.1
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Comfort
8.0
Overall
8.0
Entertainment
7.5
Food
7.0
Crew
8.6
Boarding
8.1
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Comfort
8.0
Overall
8.0
Entertainment
7.5
Food
7.0
Crew
8.6
Boarding
8.1
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Boston. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Boston?
Book flights to Boston if you plan to visit one of these locationsWaltham
Randolph
Concord
Cambridge
Brockton
Seekonk
Dedham
Cranston
Warwick
Pawtucket
Peabody
Auburn
Revere
York Beach
Londonderry
Fitchburg
North Falmouth
Swansea
Chelsea
Braintree
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Other flights to Boston
Explore flights to Boston departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 10, 2026.
Complete your trip
Complete your trip to Boston by adding a car rental and/or hotel reservation to your travel itinerary.
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Find flights from Des Moines to Boston, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Des Moines and Boston flights
Browse other Des Moines and Boston flight options. Last updated on September 10, 2026.
Other flights from Des Moines
Browse through other flights departing from Des Moines. Flights are based on user searches made on Cheapflights and were last updated on September 10, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 5 airlines flying from Des Moines to Boston
Discover the top 5 airlines that operate flights from Des Moines to Boston. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$96 | Average$198 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$173 | Average$387 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$246 | Average$492 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$310 | Average$430 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$332 | Average$464 | FlexibilityNo cancel fee | On-time69% |