$125+ Cheap flights from San Diego to Des Moines (SAN - DSM)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/17. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — DSM
May 22 — May 291
Round-trip
1 adult, Economy
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Find cheap flights from San Diego to Des Moines with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from San Diego to Des MoinesExplore the most affordable flight options available from San Diego to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 22, 2026.
Explore the most affordable flight options available from San Diego to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 22, 2026.
This Expedia deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/46:25 am
SAN
- DSM
1 stop11h 13m
Frontier
Mon 5/112:16 pm
DSM
- SAN
1 stop11h 34m
Frontier
Deal found 4/20![Frontier logo]()
$185
This Frontier deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/16:25 am
SAN
- DSM
1 stop5h 06m
Frontier
Mon 6/82:16 pm
DSM
- SAN
1 stop11h 34m
Frontier
Deal found 4/17![Frontier logo]()
$210
This Expedia deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/412:25 pm
SAN
- DSM
1 stop5h 13m
Frontier
Fri 5/82:16 pm
DSM
- SAN
1 stop11h 34m
Frontier
Deal found 4/19![Frontier logo]()
$231
This Expedia deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/269:37 am
SAN
- DSM
1 stop25h 54m
Frontier
Fri 5/292:16 pm
DSM
- SAN
1 stop11h 34m
Frontier
Deal found 4/17![Frontier logo]()
$250
This American Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/26:25 am
SAN
- DSM
1 stop5h 19m
American Airlines
Tue 6/97:02 pm
DSM
- SAN
1 stop6h 57m
American Airlines
Deal found 4/21![American Airlines logo]()
$251
This Kiwi.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/2610:07 pm
SAN
- DSM
1 stop12h 52m
Multiple Airlines
Fri 5/292:16 pm
DSM
- SAN
2 stops27h 15m
Multiple Airlines
Deal found 4/17![Multiple Airlines logo]()
$258
This Expedia deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/126:25 am
SAN
- DSM
1 stop5h 06m
Frontier
Mon 6/152:16 pm
DSM
- SAN
1 stop11h 37m
Frontier
Deal found 4/19![Frontier logo]()
$270
This Booking.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/226:25 am
SAN
- DSM
1 stop5h 06m
Frontier
Mon 5/252:16 pm
DSM
- SAN
1 stop20h 26m
Frontier
Deal found 4/20![Frontier logo]()
$278
This Booking.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/1810:04 am
SAN
- DSM
1 stop25h 27m
Frontier
Mon 6/222:16 pm
DSM
- SAN
1 stop11h 37m
Frontier
Deal found 4/21![Frontier logo]()
$283
This Frontier deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/156:25 am
SAN
- DSM
1 stop5h 06m
Frontier
Mon 5/182:16 pm
DSM
- SAN
1 stop11h 34m
Frontier
Deal found 4/18![Frontier logo]()
$290
This Kiwi.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/159:53 pm
SAN
- DSM
1 stop20h 50m
Multiple Airlines
Sun 7/199:33 pm
DSM
- SAN
1 stop25h 25m
Multiple Airlines
Deal found 4/17![Multiple Airlines logo]()
$296
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2810:15 pm
SAN
- DSM
1 stop9h 31m
Delta
Mon 6/15:28 pm
DSM
- SAN
1 stop8h 13m
Delta
Deal found 4/21![Delta logo]()
$303
Best flights from San Diego to Des MoinesDiscover carefully curated flight deals from San Diego to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 22, 2026.
Discover carefully curated flight deals from San Diego to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 22, 2026.
This United Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/28:32 pm
SAN
- DSM
2 stops11h 55m
United Airlines
Tue 6/93:01 pm
DSM
- SAN
1 stop8h 23m
United Airlines
Deal found 4/21![United Airlines logo]()
$394
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/17:10 pm
SAN
- DSM
2 stops13h 06m
Delta
Mon 6/86:03 pm
DSM
- SAN
1 stop7h 32m
Delta
Deal found 4/21![Delta logo]()
$450
This Southwest deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/2610:40 pm
SAN
- DSM
1 stop10h 55m
Southwest
Sun 6/286:10 am
DSM
- SAN
2 stops7h 50m
Southwest
Deal found 4/20![Southwest logo]()
$468
This United Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/286:35 am
SAN
- DSM
1 stop7h 40m
United Airlines
Mon 6/15:17 pm
DSM
- SAN
1 stop7h 08m
United Airlines
Deal found 4/17![United Airlines logo]()
$457
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/1710:17 pm
SAN
- DSM
1 stop9h 28m
Delta
Sun 7/265:52 pm
DSM
- SAN
1 stop7h 38m
Delta
Deal found 4/21![Delta logo]()
$533
This United Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/166:32 am
SAN
- DSM
1 stop7h 43m
United Airlines
Sat 5/231:35 pm
DSM
- SAN
2 stops12h 19m
United Airlines
Deal found 4/17![United Airlines logo]()
$487
Last-minute flights from San Diego to Des MoinesDiscover last-minute flight deals from San Diego to Des Moines. Data last updated April 22, 2026 and is based on user searches.
Discover last-minute flight deals from San Diego to Des Moines. Data last updated April 22, 2026 and is based on user searches.
This Expedia deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/46:25 am
SAN
- DSM
1 stop11h 13m
Frontier
Mon 5/112:16 pm
DSM
- SAN
1 stop11h 34m
Frontier
Deal found 4/20![Frontier logo]()
$185
This Expedia deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/412:25 pm
SAN
- DSM
1 stop5h 13m
Frontier
Fri 5/82:16 pm
DSM
- SAN
1 stop11h 34m
Frontier
Deal found 4/19![Frontier logo]()
$231
This United Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/132:14 pm
SAN
- DSM
1 stop7h 10m
United Airlines
Sat 5/165:17 pm
DSM
- SAN
1 stop5h 55m
United Airlines
Deal found 4/17![United Airlines logo]()
$337
This Frontier deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/156:25 am
SAN
- DSM
1 stop5h 06m
Frontier
Mon 5/182:16 pm
DSM
- SAN
1 stop11h 34m
Frontier
Deal found 4/18![Frontier logo]()
$290
This Expedia deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/161:00 pm
SAN
- DSM
1 stop8h 59m
Multiple Airlines
Fri 5/292:16 pm
DSM
- SAN
1 stop20h 26m
Multiple Airlines
Deal found 4/21![Multiple Airlines logo]()
$329
This eDestinos deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/189:37 am
SAN
- DSM
2 stops49h 22m
Multiple Airlines
Sun 5/3110:26 pm
DSM
- SAN
1 stop24h 46m
Multiple Airlines
Deal found 4/18![Multiple Airlines logo]()
$335
This American Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1912:51 pm
SAN
- DSM
2 stops8h 25m
American Airlines
Tue 5/264:48 pm
DSM
- SAN
1 stop9h 11m
American Airlines
Deal found 4/17![American Airlines logo]()
$342
This Booking.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/226:25 am
SAN
- DSM
1 stop5h 06m
Frontier
Mon 5/252:16 pm
DSM
- SAN
1 stop20h 26m
Frontier
Deal found 4/20![Frontier logo]()
$278
This Expedia deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/269:37 am
SAN
- DSM
1 stop25h 54m
Frontier
Fri 5/292:16 pm
DSM
- SAN
1 stop11h 34m
Frontier
Deal found 4/17![Frontier logo]()
$250
This Kiwi.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/2610:07 pm
SAN
- DSM
1 stop12h 52m
Multiple Airlines
Fri 5/292:16 pm
DSM
- SAN
2 stops27h 15m
Multiple Airlines
Deal found 4/17![Multiple Airlines logo]()
$258
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2810:15 pm
SAN
- DSM
1 stop9h 31m
Delta
Mon 6/15:28 pm
DSM
- SAN
1 stop8h 13m
Delta
Deal found 4/21![Delta logo]()
$303
One-way flights from San Diego to Des MoinesSearch for one-way flight options from San Diego to Des Moines. Find affordable one-way fares based on user searches. Data last updated April 22, 2026.
Search for one-way flight options from San Diego to Des Moines. Find affordable one-way fares based on user searches. Data last updated April 22, 2026.
This Frontier deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/176:25 am
SAN
- DSM
1 stop5h 06m
Frontier
Deal found 4/17![Frontier logo]()
$125
This Mytrip deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/3012:25 pm
SAN
- DSM
1 stop22h 44m
Frontier
Deal found 4/21![Frontier logo]()
$131
This Frontier deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/116:25 am
SAN
- DSM
1 stop5h 06m
Frontier
Deal found 4/20![Frontier logo]()
$145
This United Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/128:54 am
SAN
- DSM
1 stop5h 21m
United Airlines
Deal found 4/20![United Airlines logo]()
$156
This Kiwi.com deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/39:00 pm
SAN
- DSM
1 stop20h 25m
Multiple Airlines
Deal found 4/19![Multiple Airlines logo]()
$162
This Kiwi.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/126:25 am
SAN
- DSM
3 stops53h 21m
Multiple Airlines
Deal found 4/20![Multiple Airlines logo]()
$171
This Kiwi.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/292:12 pm
SAN
- DSM
1 stop25h 49m
Multiple Airlines
Deal found 4/20![Multiple Airlines logo]()
$172
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/169:53 pm
SAN
- DSM
2 stops22h 37m
Multiple Airlines
Deal found 4/21![Multiple Airlines logo]()
$183
This Delta deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/306:30 am
SAN
- DSM
1 stop7h 14m
Delta
Deal found 4/18![Delta logo]()
$184
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/306:47 pm
SAN
- DSM
2 stops24h 37m
Multiple Airlines
Deal found 4/21![Multiple Airlines logo]()
$200
Find flight deals from San Diego to Des Moines
Discover tips and strategies to find the most affordable flight options for your journey from San Diego (SAN) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 22, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $185 (Expedia) |
One-way from | $125 (Frontier) |
Popular in | January |
Cheapest in | November |
Average price | $449 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Diego to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 22, 2026.
Use the filters below to find and compare flights from San Diego to Des Moines that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San DiegoDes Moines
SAN - DSM
SANDSM
San Diego
Tue 6/2
8:32 pm-10:27 am
2 stops11h 55m
Des Moines
Tue 6/9
3:01 pm-9:24 pm
1 stop8h 23m
$394
San DiegoDes Moines
SAN - DSM
SANDSM
San Diego
Mon 6/1
7:10 pm-10:16 am
2 stops13h 06m
Des Moines
Mon 6/8
6:03 pm-11:35 pm
1 stop7h 32m
$450
Quickest round-trip
San DiegoDes Moines
SAN - DSM
SANDSM
San Diego
Thu 5/28
6:35 am-4:15 pm
1 stop7h 40m
Des Moines
Mon 6/1
5:17 pm-10:25 pm
1 stop7h 08m
$457
San DiegoDes Moines
SAN - DSM
SANDSM
San Diego
Fri 6/26
10:40 pm-11:35 am
1 stop10h 55m
Des Moines
Sun 6/28
6:10 am-12:00 pm
2 stops7h 50m
$468
San DiegoDes Moines
SAN - DSM
SANDSM
San Diego
Sat 5/16
6:32 am-4:15 pm
1 stop7h 43m
Des Moines
Sat 5/23
1:35 pm-11:54 pm
2 stops12h 19m
$487
San DiegoDes Moines
SAN - DSM
SANDSM
San Diego
Fri 7/17
10:17 pm-9:45 am
1 stop9h 28m
Des Moines
Sun 7/26
5:52 pm-11:30 pm
1 stop7h 38m
$533
Cheapest one-way
Quickest one-way
San DiegoDes Moines
SAN - DSM
SANDSM
San Diego
Fri 7/17
6:25 am-1:31 pm
1 stop5h 06m
$125
San DiegoDes Moines
SAN - DSM
SANDSM
San Diego
Thu 4/30
12:25 pm-1:09 pm
1 stop22h 44m
$131
San DiegoDes Moines
SAN - DSM
SANDSM
San Diego
Tue 5/12
10:55 am-11:44 pm
2 stops10h 49m
$161
San DiegoDes Moines
SAN - DSM
SANDSM
San Diego
Thu 7/16
9:53 pm-10:30 pm
2 stops22h 37m
$183
Showing 1-10 of 17 resultsSorted by cheapest first
Compare providers for flights from San Diego to Des Moines
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Diego to Des Moines in April.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on San Diego-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Diego-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Diego-Des Moines flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on San Diego-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Diego-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from San Diego to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from San Diego with our price prediction graph.
SAN-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Diego to Des Moines
What is the cheapest month to book a flight from San Diego to Des Moines?
Currently, November is the cheapest month in which you can book a flight from San Diego to Des Moines (average of $253). Flying from San Diego to Des Moines in January is currently the most expensive (average of $593). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from San Diego to Des Moines?
Reviews of airlines servicing Des Moines
Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated April 22, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andUnited Airlines from San Diego to Des Moines to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
8.0
Entertainment
7.5
Crew
8.6
Boarding
8.1
Comfort
8.0
Food
7.0
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Overall
8.0
Entertainment
7.5
Crew
8.6
Boarding
8.1
Comfort
8.0
Food
7.0
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Overall
8.0
Entertainment
7.5
Crew
8.6
Boarding
8.1
Comfort
8.0
Food
7.0
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Overall
8.0
Entertainment
7.5
Crew
8.6
Boarding
8.1
Comfort
8.0
Food
7.0
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Overall
8.0
Entertainment
7.5
Crew
8.6
Boarding
8.1
Comfort
8.0
Food
7.0
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Overall
8.0
Entertainment
7.5
Crew
8.6
Boarding
8.1
Comfort
8.0
Food
7.0
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Related info for your journey
Find useful and relevant information for your journey from San Diego to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Top 6 airlines flying from San Diego to Des Moines
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| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$69 | Average$166 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$148 | Average$322 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$158 | Average$253 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$247 | Average$471 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$286 | Average$395 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$286 | Average$462 | FlexibilityNo cancel fee | On-time71% |