$129+ Cheap flights from San Diego to Des Moines (SAN - DSM)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/24. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — DSM
Oct 15 — Oct 221
Round-trip
1 adult, Economy
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Find cheap flights from San Diego to Des Moines with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from San Diego to Des Moines
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Best
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One-way
Cheapest flights from San Diego to Des MoinesExplore the most affordable flight options available from San Diego to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2026.
Explore the most affordable flight options available from San Diego to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2026.
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/63:07 pm -
1 stop6h 00m
Tue 10/134:12 pm -
1 stop7h 34m
Deal found 9/15![American Airlines logo]()
$257
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:25 am -
1 stop11h 05m
Mon 10/128:25 pm -
1 stop21h 33m
Deal found 9/12![Frontier logo]()
$275
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/203:14 pm -
2 stops20h 38m
Fri 10/308:30 pm -
1 stop21h 28m
Deal found 9/12![Multiple Airlines logo]()
$298
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/94:29 pm -
1 stop5h 16m
Mon 10/125:06 am -
1 stop6h 01m
Deal found 9/15![American Airlines logo]()
$310
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/19:03 pm -
1 stop11h 54m
Sun 10/41:22 pm -
2 stops30h 47m
Deal found 9/11![Multiple Airlines logo]()
$323
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/136:25 am -
1 stop11h 10m
Sun 11/151:00 pm -
1 stop8h 47m
Deal found 9/11![Multiple Airlines logo]()
$335
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/46:45 pm -
2 stops22h 48m
Mon 10/128:25 pm -
1 stop21h 33m
Deal found 9/14![Frontier logo]()
$342
This Expedia deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/196:25 am -
1 stop11h 05m
Mon 10/268:25 pm -
1 stop21h 33m
Deal found 9/12![Frontier logo]()
$345
This Expedia deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected ” under the list of providers to see comparable flight deals.
Mon 10/56:25 am -
1 stop11h 08m
Fri 10/98:25 pm -
1 stop5h 31m
Deal found 9/15![Frontier logo]()
$348
Best flights from San Diego to Des MoinesDiscover carefully curated flight deals from San Diego to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 15, 2026.
Discover carefully curated flight deals from San Diego to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 15, 2026.
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/236:15 am -
1 stop5h 53m
Mon 11/307:55 pm -
1 stop5h 58m
Deal found 9/15![Delta logo]()
$405
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/162:24 pm -
2 stops7h 24m
Mon 10/195:22 pm -
1 stop7h 05m
Deal found 9/15![United Airlines logo]()
$429
This Expedia deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/49:10 am -
1 stop7h 48m
Mon 10/128:25 pm -
1 stop5h 31m
Deal found 9/14![Multiple Airlines logo]()
$463
This Southwest deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/98:35 am -
2 stops7h 55m
Mon 10/127:10 pm -
2 stops7h 00m
Deal found 9/12![Southwest logo]()
$514
This Alaska Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/69:10 am -
1 stop7h 50m
Sat 10/109:26 am -
1 stop9h 35m
Deal found 9/15![Alaska Airlines logo]()
$541
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/92:24 pm -
2 stops7h 24m
Mon 10/125:22 pm -
1 stop7h 05m
Deal found 9/11![United Airlines logo]()
$526
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/411:55 am -
2 stops7h 40m
Mon 10/127:10 pm -
2 stops7h 00m
Deal found 9/14![Southwest logo]()
$583
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2611:21 am -
1 stop26h 46m
Tue 12/19:30 am -
2 stops12h 38m
Deal found 9/14![United Airlines logo]()
$609
Last-minute flights from San Diego to Des MoinesDiscover last-minute flight deals from San Diego to Des Moines. Data last updated September 15, 2026 and is based on user searches.
Discover last-minute flight deals from San Diego to Des Moines. Data last updated September 15, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/19:03 pm -
1 stop11h 54m
Sun 10/41:22 pm -
2 stops30h 47m
Deal found 9/11![Multiple Airlines logo]()
$323
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/46:45 pm -
2 stops22h 48m
Mon 10/128:25 pm -
1 stop21h 33m
Deal found 9/14![Frontier logo]()
$342
This Expedia deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/56:25 am -
1 stop11h 08m
Fri 10/98:25 pm -
1 stop5h 31m
Deal found 9/15![Frontier logo]()
$348
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/63:07 pm -
1 stop6h 00m
Tue 10/134:12 pm -
1 stop7h 34m
Deal found 9/15![American Airlines logo]()
$257
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:25 am -
1 stop11h 05m
Mon 10/128:25 pm -
1 stop21h 33m
Deal found 9/12![Frontier logo]()
$275
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/94:29 pm -
1 stop5h 16m
Mon 10/125:06 am -
1 stop6h 01m
Deal found 9/15![American Airlines logo]()
$310
This Expedia deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/196:25 am -
1 stop11h 05m
Mon 10/268:25 pm -
1 stop21h 33m
Deal found 9/12![Frontier logo]()
$345
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/196:25 am -
1 stop11h 05m
Mon 10/269:11 pm -
2 stops23h 27m
Deal found 9/12![Multiple Airlines logo]()
$351
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/203:14 pm -
2 stops20h 38m
Fri 10/308:30 pm -
1 stop21h 28m
Deal found 9/12![Multiple Airlines logo]()
$298
One-way flights from San Diego to Des MoinesSearch for one-way flight options from San Diego to Des Moines. Find affordable one-way fares based on user searches. Data last updated September 15, 2026.
Search for one-way flight options from San Diego to Des Moines. Find affordable one-way fares based on user searches. Data last updated September 15, 2026.
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/244:30 pm -
1 stop5h 06m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![American Airlines logo]()
$129
This Expedia deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/56:25 am -
1 stop11h 08m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Frontier logo]()
$134
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/153:14 pm -
2 stops17h 43m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![Multiple Airlines logo]()
$135
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/287:33 pm -
2 stops25h 17m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![Multiple Airlines logo]()
$139
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/153:07 pm -
1 stop6h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![American Airlines logo]()
$147
This Expedia deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:25 am -
1 stop11h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![Frontier logo]()
$162
This Orbitz deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:25 am -
1 stop11h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/12![Frontier logo]()
$172
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/56:15 am -
2 stops8h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![United Airlines logo]()
$183
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/235:54 pm -
1 stop25h 12m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/13![Multiple Airlines logo]()
$191
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/316:25 am -
3 stops30h 34m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/12![Multiple Airlines logo]()
$196
Find flight deals from San Diego to Des Moines
Discover tips and strategies to find the most affordable flight options for your journey from San Diego (SAN) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 15, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $257 (American Airlines) |
One-way from | $129 (American Airlines) |
Popular in | January |
Cheapest in | November |
Average price | $354 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Diego to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 15, 2026.
Use the filters below to find and compare flights from San Diego to Des Moines that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San DiegoDes Moines
SAN San Diego - DSM Des Moines
SANDSM
San Diego
Mon 10/5
6:25 am-7:33 pm
1 stop11h 08m
Des Moines
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$134
San DiegoDes Moines
SAN San Diego - DSM Des Moines
SANDSM
San Diego
Thu 10/15
3:14 pm-10:57 am
2 stops17h 43m
Des Moines
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$135
San DiegoDes Moines
SAN San Diego - DSM Des Moines
SANDSM
San Diego
Fri 10/9
6:25 am-7:30 pm
1 stop11h 05m
Des Moines
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$162
San DiegoDes Moines
SAN San Diego - DSM Des Moines
SANDSM
San Diego
Mon 10/5
6:15 am-4:20 pm
2 stops8h 05m
Des Moines
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$183
San DiegoDes Moines
SAN San Diego - DSM Des Moines
SANDSM
San Diego
Wed 10/28
10:56 am-10:01 pm
2 stops33h 05m
Des Moines
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$199
San DiegoDes Moines
SAN San Diego - DSM Des Moines
SANDSM
San Diego
Thu 9/24
4:54 pm-7:33 pm
1 stop24h 39m
Des Moines
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$201
San DiegoDes Moines
SAN San Diego - DSM Des Moines
SANDSM
San Diego
Sat 10/31
7:40 am-5:45 pm
2 stops8h 05m
Des Moines
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$231
Quickest round-trip
San DiegoDes Moines
SAN San Diego - DSM Des Moines
SANDSM
San Diego
Fri 10/30
6:55 am-3:50 pm
2 stops6h 55m
Des Moines
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$231
San DiegoDes Moines
SAN San Diego - DSM Des Moines
SANDSM
San Diego
Thu 11/19
10:20 am-8:50 pm
2 stops8h 30m
Des Moines
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$234
San DiegoDes Moines
SAN San Diego - DSM Des Moines
SANDSM
San Diego
Wed 11/25
9:35 pm-12:50 pm
2 stops13h 15m
Des Moines
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$240
Showing 1-10 of 18 resultsSorted by cheapest first
Compare providers for flights from San Diego to Des Moines
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Diego to Des Moines in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star |
- Most accurate provider: When it comes to deals on San Diego-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Diego-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Diego-Des Moines flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on San Diego-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Diego-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from San Diego to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from San Diego with our price prediction graph.
SAN-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Diego to Des Moines
What is the cheapest month to book a flight from San Diego to Des Moines?
Currently, November is the cheapest month in which you can book a flight from San Diego to Des Moines (average of $261). Flying from San Diego to Des Moines in January is currently the most expensive (average of $890). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from San Diego to Des Moines?
Airfare is below average for this route at the moment.
San Diego to Des Moines flights typically cost between $268 and $391 in October.The cheapest round-trip price found within the last 5 days was $257 on American Airlines (Oct 6-Oct 13).
Reviews of airlines servicing Des Moines
Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated September 15, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andUnited Airlines from San Diego to Des Moines to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.5
Food
7.0
Comfort
8.0
Overall
8.0
Crew
8.6
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Entertainment
7.5
Food
7.0
Comfort
8.0
Overall
8.0
Crew
8.6
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Entertainment
7.5
Food
7.0
Comfort
8.0
Overall
8.0
Crew
8.6
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Entertainment
7.5
Food
7.0
Comfort
8.0
Overall
8.0
Crew
8.6
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Entertainment
7.5
Food
7.0
Comfort
8.0
Overall
8.0
Crew
8.6
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Entertainment
7.5
Food
7.0
Comfort
8.0
Overall
8.0
Crew
8.6
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Related info for your journey
Find useful and relevant information for your journey from San Diego to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsAltoona
Clive
Ames
Johnston
West Des Moines
Boone
Norwalk
Ankeny
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Other flights to Des Moines
Explore flights to Des Moines departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 15, 2026.
Search flights from San Diego to Des Moines by cabin class
Find flights from San Diego to Des Moines, based on your preferred cabin class, be it economy, premium economy, business, or first class.
San Diego and Des Moines flights
Browse other San Diego and Des Moines flight options. Last updated on September 15, 2026.
Other flights from San Diego
Browse through other flights departing from San Diego. Flights are based on user searches made on Cheapflights and were last updated on September 15, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 5 airlines flying from San Diego to Des Moines
Discover the top 5 airlines that operate flights from San Diego to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 15, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$95 | Average$288 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$148 | Average$322 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$208 | Average$453 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$296 | Average$396 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$310 | Average$566 | FlexibilityNo cancel fee | On-time63% |