$124+ Cheap flights from San Diego to Des Moines (SAN - DSM)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/3. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — DSM
Dec 4 — Dec 111
Round-trip
1 adult, Economy
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Find cheap flights from San Diego to Des Moines with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from San Diego to Des Moines
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Cheapest flights from San Diego to Des MoinesExplore the most affordable flight options available from San Diego to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 4, 2026.
Explore the most affordable flight options available from San Diego to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 4, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/247:56 pm -
1 stop18h 09m
Tue 12/298:23 pm -
1 stop18h 01m
Deal found 10/30![Multiple Airlines logo]()
$278
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/99:58 am -
1 stop22h 52m
Thu 1/148:26 pm -
1 stop29h 32m
Deal found 11/3![Multiple Airlines logo]()
$287
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/266:15 am -
1 stop6h 20m
Tue 12/12:28 pm -
1 stop5h 57m
Deal found 11/1![American Airlines logo]()
$355
This Cheapflightsfares deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/136:25 am -
1 stop11h 10m
Mon 11/168:30 pm -
1 stop21h 28m
Deal found 10/30![Frontier logo]()
$358
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/88:40 am -
2 stops8h 39m
Wed 1/131:35 pm -
1 stop5h 41m
Deal found 11/3![United Airlines logo]()
$360
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/214:25 pm -
1 stop5h 19m
Thu 12/315:00 am -
1 stop5h 40m
Deal found 11/3![American Airlines logo]()
$368
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/186:15 am -
1 stop5h 36m
Wed 12/237:43 pm -
1 stop6h 02m
Deal found 11/3![American Airlines logo]()
$372
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1811:06 am -
2 stops32h 50m
Sun 11/223:00 pm -
1 stop18h 55m
Deal found 11/3![Multiple Airlines logo]()
$388
Best flights from San Diego to Des MoinesDiscover carefully curated flight deals from San Diego to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 4, 2026.
Discover carefully curated flight deals from San Diego to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 4, 2026.
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/186:15 am -
1 stop5h 36m
Wed 12/237:43 pm -
1 stop6h 02m
Deal found 11/3![American Airlines logo]()
$372
This United Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/162:30 pm -
2 stops7h 12m
Fri 11/205:30 am -
1 stop5h 40m
Deal found 11/1![United Airlines logo]()
$396
This Southwest deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/910:30 am -
2 stops8h 20m
Thu 1/1410:50 am -
2 stops8h 15m
Deal found 11/3![Southwest logo]()
$492
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/236:45 am -
1 stop7h 22m
Sat 11/285:30 am -
1 stop5h 40m
Deal found 10/30![United Airlines logo]()
$436
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/256:45 am -
1 stop7h 22m
Sat 11/285:30 am -
1 stop5h 40m
Deal found 11/2![United Airlines logo]()
$447
This United Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/1210:30 am -
1 stop9h 07m
Sat 1/239:25 am -
1 stop7h 53m
Deal found 10/31![United Airlines logo]()
$465
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/176:20 am -
2 stops12h 05m
Tue 12/225:30 am -
2 stops8h 05m
Deal found 11/3![United Airlines logo]()
$475
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/192:08 pm -
1 stop6h 51m
Mon 11/235:30 am -
1 stop5h 40m
Deal found 11/2![United Airlines logo]()
$483
Last-minute flights from San Diego to Des MoinesDiscover last-minute flight deals from San Diego to Des Moines. Data last updated November 4, 2026 and is based on user searches.
Discover last-minute flight deals from San Diego to Des Moines. Data last updated November 4, 2026 and is based on user searches.
This Cheapflightsfares deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/136:25 am -
1 stop11h 10m
Mon 11/168:30 pm -
1 stop21h 28m
Deal found 10/30![Frontier logo]()
$358
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1811:06 am -
2 stops32h 50m
Sun 11/223:00 pm -
1 stop18h 55m
Deal found 11/3![Multiple Airlines logo]()
$388
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/266:15 am -
1 stop6h 20m
Tue 12/12:28 pm -
1 stop5h 57m
Deal found 11/1![American Airlines logo]()
$355
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/88:40 am -
2 stops8h 39m
Wed 1/131:35 pm -
1 stop5h 41m
Deal found 11/3![United Airlines logo]()
$360
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/99:58 am -
1 stop22h 52m
Thu 1/148:26 pm -
1 stop29h 32m
Deal found 11/3![Multiple Airlines logo]()
$287
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/186:15 am -
1 stop5h 36m
Wed 12/237:43 pm -
1 stop6h 02m
Deal found 11/3![American Airlines logo]()
$372
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/214:25 pm -
1 stop5h 19m
Thu 12/315:00 am -
1 stop5h 40m
Deal found 11/3![American Airlines logo]()
$368
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/247:56 pm -
1 stop18h 09m
Tue 12/298:23 pm -
1 stop18h 01m
Deal found 10/30![Multiple Airlines logo]()
$278
One-way flights from San Diego to Des MoinesSearch for one-way flight options from San Diego to Des Moines. Find affordable one-way fares based on user searches. Data last updated November 4, 2026.
Search for one-way flight options from San Diego to Des Moines. Find affordable one-way fares based on user searches. Data last updated November 4, 2026.
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/39:05 am -
1 stop11h 21m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![Multiple Airlines logo]()
$124
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/275:26 pm -
1 stop24h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![Frontier logo]()
$125
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/123:30 pm -
2 stops47h 34m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![Multiple Airlines logo]()
$129
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/265:26 pm -
2 stops41h 53m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![Multiple Airlines logo]()
$130
This Cheapflightsfares deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/234:16 pm -
1 stop25h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/30![Frontier logo]()
$132
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/49:05 am -
1 stop9h 23m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![Multiple Airlines logo]()
$145
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/158:57 am -
2 stops25h 58m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![Multiple Airlines logo]()
$146
This Cheapflightsfares deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/136:30 am -
1 stop11h 12m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![Frontier logo]()
$148
This Travelocity deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/66:30 am -
1 stop11h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/1![Frontier logo]()
$150
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/236:36 am -
2 stops28h 43m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![Multiple Airlines logo]()
$154
This Frontier deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/246:36 am -
1 stop10h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![Frontier logo]()
$155
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/1611:14 am -
1 stop30h 17m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![Frontier logo]()
$156
Find flight deals from San Diego to Des Moines
Discover tips and strategies to find the most affordable flight options for your journey from San Diego (SAN) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 4, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $278 (Kiwi.com) |
One-way from | $124 (Kiwi.com) |
Popular in | January |
Cheapest in | September |
Average price | $415 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Diego to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 4, 2026.
Use the filters below to find and compare flights from San Diego to Des Moines that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San DiegoDes Moines
SAN San Diego - DSM Des Moines
SANDSM
San Diego
Tue 1/26
5:26 pm-1:19 pm
2 stops41h 53m
Des Moines
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$130
San DiegoDes Moines
SAN San Diego - DSM Des Moines
SANDSM
San Diego
Wed 12/23
4:16 pm-7:31 pm
1 stop25h 15m
Des Moines
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$132
San DiegoDes Moines
SAN San Diego - DSM Des Moines
SANDSM
San Diego
Tue 1/12
3:09 pm-1:19 pm
3 stops44h 10m
Des Moines
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$156
San DiegoDes Moines
SAN San Diego - DSM Des Moines
SANDSM
San Diego
Tue 1/26
11:43 am-9:14 pm
1 stop7h 31m
Des Moines
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$178
San DiegoDes Moines
SAN San Diego - DSM Des Moines
SANDSM
San Diego
Sat 12/19
10:33 pm-9:12 am
1 stop8h 39m
Des Moines
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$178
Quickest round-trip
San DiegoDes Moines
SAN San Diego - DSM Des Moines
SANDSM
San Diego
Tue 12/15
1:50 pm-8:50 pm
1 stop5h 00m
Des Moines
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$178
San DiegoDes Moines
SAN San Diego - DSM Des Moines
SANDSM
San Diego
Tue 1/12
6:15 am-4:12 pm
1 stop7h 57m
Des Moines
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$178
San DiegoDes Moines
SAN San Diego - DSM Des Moines
SANDSM
San Diego
Mon 1/25
7:41 pm-10:41 am
2 stops13h 00m
Des Moines
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$183
San DiegoDes Moines
SAN San Diego - DSM Des Moines
SANDSM
San Diego
Thu 12/17
2:45 pm-11:59 pm
2 stops7h 14m
Des Moines
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$183
San DiegoDes Moines
SAN San Diego - DSM Des Moines
SANDSM
San Diego
Sat 12/19
12:04 pm-7:31 pm
2 stops29h 27m
Des Moines
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$184
Showing 1-10 of 20 resultsSorted by cheapest first
Compare providers for flights from San Diego to Des Moines
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Diego to Des Moines in November.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star |
- Most accurate provider: When it comes to deals on San Diego-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Diego-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Diego-Des Moines flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on San Diego-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Diego-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from San Diego to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from San Diego with our price prediction graph.
SAN-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Diego to Des Moines
What is the cheapest month to book a flight from San Diego to Des Moines?
Currently, September is the cheapest month in which you can book a flight from San Diego to Des Moines (average of $354). Flying from San Diego to Des Moines in January is currently the most expensive (average of $890). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from San Diego to Des Moines?
Airfare is below average for this route at the moment.
San Diego to Des Moines flights typically cost between $396 and $572 in December.The cheapest round-trip price found within the last 5 days was $278 on Multiple Airlines (Dec 24-Dec 29).
Reviews of airlines servicing Des Moines
Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated November 4, 2026.
Peruse reviews from past customers who have flown with Southwest,United Airlines, andAmerican Airlines from San Diego to Des Moines to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
8.0
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Food
7.0
Crew
8.6
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Overall
8.0
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Food
7.0
Crew
8.6
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Overall
8.0
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Food
7.0
Crew
8.6
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Overall
8.0
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Food
7.0
Crew
8.6
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Overall
8.0
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Food
7.0
Crew
8.6
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Related info for your journey
Find useful and relevant information for your journey from San Diego to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsAltoona
Clive
West Des Moines
Ames
Johnston
Boone
Norwalk
Ankeny
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Other flights to Des Moines
Explore flights to Des Moines departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on November 4, 2026.
Search flights from San Diego to Des Moines by cabin class
Find flights from San Diego to Des Moines, based on your preferred cabin class, be it economy, premium economy, business, or first class.
San Diego and Des Moines flights
Browse other San Diego and Des Moines flight options. Last updated on November 4, 2026.
Other flights from San Diego
Browse through other flights departing from San Diego. Flights are based on user searches made on Cheapflights and were last updated on November 4, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 4 airlines flying from San Diego to Des Moines
Discover the top 4 airlines that operate flights from San Diego to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 4, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$95 | Average$288 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$208 | Average$453 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$296 | Average$396 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$336 | Average$492 | FlexibilityNo cancel fee | On-time63% |