HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Des Moines

$64+ Cheap flights from Santa Ana to Des Moines (SNA - DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/25. Fares are subject to change and may not be available on all flights or dates of travel.
SNA — DSM
jul. 16 — jul. 231
mié. 7/16
mié. 7/23
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Santa Ana to Des Moines with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from Santa Ana J. Wayne/Orange Cnty to Des Moines are usually found in February or January, booked 77 days in advance, depart on a Wednesday or Friday and return on a Saturday

Cheap flight deals from Santa Ana to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Santa Ana (SNA) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated julio 11, 2025.

Round-trip from

$108
(Cheapflightsfares)

One-way from

$64
(Booking.com)

Popular in

October

Cheapest in

February

Average price

$412

Good round-trip deal

$247 or less

Good one-way deal

$64 or less
From Santa Ana J. Wayne/Orange Cnty to Des Moines
Search Deals
One-way flight from Santa Ana J. Wayne/Orange Cnty to Des Moines
Search Deals
Highest demand for flights based on searches. 11% potential increase in price ($45 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($11 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in July 2025
Search Deals
Price to beat on a round-trip flight from Santa Ana J. Wayne/Orange Cnty to Des Moines.
Search Deals
Price to beat on a one-way flight from Santa Ana J. Wayne/Orange Cnty to Des Moines.
Search Deals

Find flight deals from Santa Ana to Des Moines

Cheapest flights from Santa Ana to Des Moines
Explore the most affordable flight options available from Santa Ana to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on julio 11, 2025.

This Cheapflightsfares deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 9/1110:33 amSNA - DSM
Nonstop3h 15mAllegiant Air
dom. 9/148:00 amDSM - SNA
Nonstop3h 43mAllegiant Air
Deal found 7/10$108
This Mytrip deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 9/116:45 amSNA - DSM
1 stop13h 56mMultiple Airlines
dom. 9/148:00 amDSM - SNA
Nonstop3h 43mMultiple Airlines
Deal found 7/10$154
This American Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 9/2610:01 amSNA - DSM
1 stop6h 28mAmerican Airlines
lun. 9/295:55 pmDSM - SNA
1 stop5h 52mAmerican Airlines
Deal found 7/8$192
This FlightHub deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/1312:01 pmSNA - DSM
1 stop5h 58mFrontier
lun. 11/178:44 pmDSM - SNA
1 stop16h 32mFrontier
Deal found 7/10$268
This Delta deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 8/88:00 amSNA - DSM
1 stop7h 09mDelta
mié. 8/135:44 amDSM - SNA
1 stop7h 09mDelta
Deal found 7/10$288
This United Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 11/1411:15 amSNA - DSM
1 stop7h 30mUnited Airlines
mar. 11/185:14 pmDSM - SNA
1 stop5h 39mUnited Airlines
Deal found 7/9$295
This Southwest deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 10/131:35 pmSNA - DSM
1 stop6h 00mSouthwest
mié. 10/1510:15 amDSM - SNA
1 stop11h 15mSouthwest
Deal found 7/10$313

Cheapflights Fare Finder

Customize your flight search to find flights from Santa Ana to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated julio 11, 2025.
Use the filters below to find and compare flights from Santa Ana to Des Moines that are best for you.

Fly from

Santa Ana

Fly to

Des Moines

Route

Depart

Return

Price

Santa AnaDes Moines

SNA - DSM

SNADSM

Santa Ana J. Wayne/Orange Cnty

jue. 9/11

10:33 am-3:48 pm

Nonstop3h 15m

Des Moines

dom. 9/14

8:00 am-9:43 am

Nonstop3h 43m

$108

Santa AnaDes Moines

SNA - DSM

SNADSM

Santa Ana J. Wayne/Orange Cnty

jue. 9/11

6:45 am-10:41 pm

1 stop13h 56m

Des Moines

dom. 9/14

8:00 am-9:43 am

Nonstop3h 43m

$154

Santa AnaDes Moines

SNA - DSM

SNADSM

Santa Ana J. Wayne/Orange Cnty

vie. 9/26

10:01 am-6:29 pm

1 stop6h 28m

Des Moines

lun. 9/29

5:55 pm-9:47 pm

1 stop5h 52m

$192

Santa AnaDes Moines

SNA - DSM

SNADSM

Santa Ana J. Wayne/Orange Cnty

jue. 11/13

12:01 pm-7:59 pm

1 stop5h 58m

Des Moines

lun. 11/17

8:44 pm-11:16 am

1 stop16h 32m

$268

Santa AnaDes Moines

SNA - DSM

SNADSM

Santa Ana J. Wayne/Orange Cnty

vie. 8/8

8:00 am-5:09 pm

1 stop7h 09m

Des Moines

mié. 8/13

5:44 am-10:53 am

1 stop7h 09m

$288

Santa AnaDes Moines

SNA - DSM

SNADSM

Santa Ana J. Wayne/Orange Cnty

vie. 11/14

11:15 am-8:45 pm

1 stop7h 30m

Des Moines

mar. 11/18

5:14 pm-8:53 pm

1 stop5h 39m

$295

Santa AnaDes Moines

SNA - DSM

SNADSM

Santa Ana J. Wayne/Orange Cnty

lun. 10/13

1:35 pm-9:35 pm

1 stop6h 00m

Des Moines

mié. 10/15

10:15 am-7:30 pm

1 stop11h 15m

$313

Santa AnaDes Moines

SNA - DSM

SNADSM

Santa Ana J. Wayne/Orange Cnty

jue. 9/25

10:33 am-3:48 pm

Nonstop3h 15m

$64

Santa AnaDes Moines

SNA - DSM

SNADSM

Santa Ana J. Wayne/Orange Cnty

jue. 9/25

12:53 pm-11:30 pm

1 stop8h 37m

$85

Santa AnaDes Moines

SNA - DSM

SNADSM

Santa Ana J. Wayne/Orange Cnty

lun. 8/25

6:45 am-4:45 pm

2 stops8h 00m

$123

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/9

Showing 1-10 of 14 results
1
2

Best time to book a flight from Santa Ana to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Santa Ana with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santa Ana to Des Moines

How far ahead should I book a flight from Santa Ana to Des Moines?

Use this chart to determine the optimal time to book a round-trip flight from Santa Ana to Des Moines. Price data was last updated on June 27, 2025.

To ensure you get the cheapest price possible for a flight from Santa Ana to Des Moines, you should look to book at least 77 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Santa Ana to Des Moines?

Currently, August is the cheapest month in which you can book a flight from Santa Ana to Des Moines (average of $336). Flying from Santa Ana to Des Moines in June is currently the most expensive (average of $402). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SNA to DSM?

Find hourly flight availability from Santa Ana to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated julio 11, 2025.

A simple way to save on the total cost of your ticket is to fly from Santa Ana to Des Moines in the afternoon. If you’re flexible enough to do this you can expect to save up to 74% on your trip compared to booking a flight at noon.

Reviews of airlines servicing Des Moines

Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated julio 11, 2025.
Read reviews from past customers who have flown Alaska Airlines, Southwest, and Delta from Santa Ana to Des Moines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
10,000 reviews

Entertainment

7.1

Comfort

7.8

Crew

8.5

Boarding

8.1

Overall

8.0

Food

7.1

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Alaska Airlines
8.0
Very good
10,000 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Entertainment

7.1

Comfort

7.8

Crew

8.5

Boarding

8.1

Overall

8.0

Food

7.1

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Southwest
8.0
Very good
4,250 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Entertainment

7.1

Comfort

7.8

Crew

8.5

Boarding

8.1

Overall

8.0

Food

7.1

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Delta
8.0
Very good
7,952 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Entertainment

7.1

Comfort

7.8

Crew

8.5

Boarding

8.1

Overall

8.0

Food

7.1

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
United Airlines
7.4
Good
8,846 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Entertainment

7.1

Comfort

7.8

Crew

8.5

Boarding

8.1

Overall

8.0

Food

7.1

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
American Airlines
7.2
Good
10,000 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Entertainment

7.1

Comfort

7.8

Crew

8.5

Boarding

8.1

Overall

8.0

Food

7.1

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.

Related info for your journey

Find useful and relevant information for your journey from Santa Ana to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Santa Ana to Des Moines flight route?

    Flights from Santa Ana J. Wayne/Orange Cnty to Des Moines have been viewed 2 times in the past calendar month.

  • What are the cheapest airlines flying from Santa Ana to Des Moines round-trip?

    According to our current data, Allegiant Air ($108), American Airlines ($192), and Frontier ($268) offers the cheapest pricing from Santa Ana to Des Moines. Allegiant Air is 68% cheaper than the average price of flights available within the next 90 days to this destination.

  • What are the cheapest airlines to fly from Santa Ana to Des Moines one-way?

    The cheapest airlines for a one-way flight from Santa Ana to Des Moines are Allegiant Air ($64), American Airlines ($85), and Southwest ($123).

  • What are the cheapest flights from Santa Ana to Des Moines?

    While on average a flight from Santa Ana to Des Moines is generally $231, our data shows the cheapest flight currently is $64. When looking at the most popular route, (Santa Ana J. Wayne/Orange Cnty - Des Moines), you can expect to pay $127 for that flight.

  • Can I find deals for flights from Santa Ana to Des Moines that include hotel bookings?

    Yes. In addition to deals on Santa Ana to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santa Ana to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Ana to Des Moines.

  • Can I find deals for business class flights from Santa Ana to Des Moines?

    Yes. Cheapflights offers flight deals from Santa Ana to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santa Ana to Des Moines?

    Currently, August is the cheapest month in which you can book a flight from Santa Ana to Des Moines (average of $336). Flying from Santa Ana to Des Moines in June is currently the most expensive (average of $402). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santa Ana?

Book flights to Santa Ana if you plan to visit one of these locations
Altoona
Ames
Johnston
Boone
West Des Moines
Ankeny

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Santa Ana to Des Moines

See prices for flight routes from nearby airports that may be better suited for you.
Los Angeles to Omaha flights
San Francisco to Omaha flights
Los Angeles to Des Moines flights
Santa Ana to Omaha flights
Ontario to Des Moines flights
Ontario to Omaha flights
San Francisco to Des Moines flights
Los Angeles to Cedar Rapids flights
San Diego to Cedar Rapids flights
San Diego to Omaha flights
Las Vegas to Omaha flights
San Francisco to Moline flights
Palm Springs to Omaha flights
San Diego to Moline flights
Burbank to Des Moines flights
San Jose to Omaha flights
San Diego to Des Moines flights
Oakland to Omaha flights
San Francisco to Cedar Rapids flights
Sacramento to Des Moines flights
Burbank to Omaha flights
Las Vegas to Des Moines flights
Oakland to Des Moines flights
San Jose to Cedar Rapids flights
Fresno to Des Moines flights
Ontario to Cedar Rapids flights
San Jose to Des Moines flights
Santa Ana to Cedar Rapids flights
Long Beach to Omaha flights
Los Angeles to Moline flights
Sacramento to Cedar Rapids flights
Reno to Omaha flights
Santa Barbara to Des Moines flights
Sacramento to Omaha flights
Ontario to Moline flights
Fresno to Cedar Rapids flights
Monterey to Omaha flights
Medford to Cedar Rapids flights
Fresno to Omaha flights
Reno to Cedar Rapids flights
Las Vegas to Cedar Rapids flights
Long Beach to Des Moines flights
Reno to Des Moines flights
Arcata to Omaha flights
Los Angeles to Sioux City flights
Bakersfield to Des Moines flights
San Luis Obispo to Omaha flights
Sacramento to Moline flights
Santa Ana to Sioux City flights

Top 4 airlines flying from Santa Ana to Des Moines

Discover the top 4 airlines that operate flights from Santa Ana to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated julio 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$124Average$206FlexibilityNo cancel feeOn-time88%
United AirlinesCheapest$316Average$668FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$336Average$436FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$358Average$456FlexibilityNo cancel feeOn-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.