$90+ Cheap flights from Santa Ana, CA to Des Moines (SNA - DSM)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/10. Fares are subject to change and may not be available on all flights or dates of travel.
SNA — DSM
Sep 9 — Sep 161
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Santa Ana to Des MoinesExplore the most affordable flight options available from Santa Ana to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 10, 2026.
Explore the most affordable flight options available from Santa Ana to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 10, 2026.
This Cheapflightsfares deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/224:46 pm -
Nonstop3h 15m
Sun 10/252:18 pm -
Nonstop3h 38m
Deal found 8/10![Allegiant Air logo]()
$126
This Booking.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/19:28 am -
Nonstop3h 15m
Sun 10/47:00 am -
Nonstop3h 38m
Deal found 8/7![Allegiant Air logo]()
$133
This Cheapflightsfares deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/84:46 pm -
Nonstop3h 15m
Sun 10/111:38 pm -
Nonstop3h 38m
Deal found 8/6![Allegiant Air logo]()
$140
This Cheapflightsfares deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1012:27 pm -
Nonstop3h 17m
Sun 9/2010:00 am -
Nonstop3h 37m
Deal found 8/5![Allegiant Air logo]()
$149
This Cheapflightsfares deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/612:27 pm -
Nonstop3h 17m
Sun 9/2010:00 am -
Nonstop3h 37m
Deal found 8/7![Allegiant Air logo]()
$152
This Booking.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2712:26 pm -
Nonstop3h 17m
Sun 8/3010:00 am -
Nonstop3h 36m
Deal found 8/7![Allegiant Air logo]()
$163
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/104:35 pm -
1 stop26h 06m
Sun 9/2010:00 am -
Nonstop3h 37m
Deal found 8/5![Multiple Airlines logo]()
$188
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/14:35 pm -
1 stop16h 22m
Sun 10/47:00 am -
Nonstop3h 38m
Deal found 8/8![Multiple Airlines logo]()
$190
This Cheapflightsfares deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/612:27 pm -
Nonstop3h 17m
Sun 9/1310:00 am -
Nonstop3h 37m
Deal found 8/7![Allegiant Air logo]()
$197
This Kiwi.com deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/224:46 pm -
Nonstop3h 15m
Mon 10/269:11 pm -
1 stop19h 52m
Deal found 8/9![Multiple Airlines logo]()
$199
Best flights from Santa Ana to Des MoinesDiscover carefully curated flight deals from Santa Ana to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 10, 2026.
Discover carefully curated flight deals from Santa Ana to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 10, 2026.
This United Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/68:55 am -
2 stops10h 28m
Mon 9/75:45 am -
1 stop5h 22m
Deal found 8/6![United Airlines logo]()
$375
This Delta deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/217:10 am -
2 stops11h 52m
Fri 10/233:03 pm -
1 stop9h 09m
Deal found 8/5![Delta logo]()
$408
This Southwest deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2111:00 am -
2 stops7h 35m
Fri 10/236:20 am -
2 stops8h 40m
Deal found 8/5![Southwest logo]()
$431
This Delta deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/512:15 pm -
1 stop8h 22m
Wed 9/95:45 am -
1 stop8h 48m
Deal found 8/5![Delta logo]()
$426
This Southwest deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/69:00 am -
2 stops7h 15m
Mon 9/72:25 pm -
2 stops8h 35m
Deal found 8/6![Southwest logo]()
$500
This United Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/68:55 am -
2 stops10h 28m
Sun 9/135:45 am -
2 stops10h 12m
Deal found 8/9![United Airlines logo]()
$507
This Delta deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:02 pm -
2 stops14h 09m
Tue 10/273:46 pm -
2 stops8h 19m
Deal found 8/8![Delta logo]()
$468
This Delta deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:02 pm -
2 stops14h 09m
Wed 10/2810:57 am -
2 stops9h 25m
Deal found 8/8![Delta logo]()
$468
This United Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/228:00 pm -
2 stops12h 31m
Sun 10/255:30 am -
1 stop6h 10m
Deal found 8/5![United Airlines logo]()
$516
This Delta deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/119:53 am -
2 stops9h 20m
Sun 11/152:43 pm -
1 stop8h 11m
Deal found 8/6![Delta logo]()
$502
This Delta deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/196:02 pm -
2 stops14h 09m
Sat 10/244:01 pm -
2 stops8h 04m
Deal found 8/9![Delta logo]()
$507
Last-minute flights from Santa Ana to Des MoinesDiscover last-minute flight deals from Santa Ana to Des Moines. Data last updated August 10, 2026 and is based on user searches.
Discover last-minute flight deals from Santa Ana to Des Moines. Data last updated August 10, 2026 and is based on user searches.
This Booking.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2712:26 pm -
Nonstop3h 17m
Sun 8/3010:00 am -
Nonstop3h 36m
Deal found 8/7![Allegiant Air logo]()
$163
This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2712:26 pm -
Nonstop3h 17m
Sun 8/309:50 pm -
1 stop20h 25m
Deal found 8/7![Multiple Airlines logo]()
$202
This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2712:26 pm -
Nonstop3h 17m
Mon 8/318:54 pm -
1 stop20h 07m
Deal found 8/7![Multiple Airlines logo]()
$203
This Cheapflightsfares deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/312:27 pm -
Nonstop3h 17m
Sun 9/610:00 am -
Nonstop3h 37m
Deal found 8/8![Allegiant Air logo]()
$247
This Cheapflightsfares deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/612:27 pm -
Nonstop3h 17m
Sun 9/2010:00 am -
Nonstop3h 37m
Deal found 8/7![Allegiant Air logo]()
$152
This Cheapflightsfares deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/612:27 pm -
Nonstop3h 17m
Sun 9/1310:00 am -
Nonstop3h 37m
Deal found 8/7![Allegiant Air logo]()
$197
This Cheapflightsfares deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1012:27 pm -
Nonstop3h 17m
Sun 9/2010:00 am -
Nonstop3h 37m
Deal found 8/5![Allegiant Air logo]()
$149
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/104:35 pm -
1 stop26h 06m
Sun 9/2010:00 am -
Nonstop3h 37m
Deal found 8/5![Multiple Airlines logo]()
$188
One-way flights from Santa Ana to Des MoinesSearch for one-way flight options from Santa Ana to Des Moines. Find affordable one-way fares based on user searches. Data last updated August 10, 2026.
Search for one-way flight options from Santa Ana to Des Moines. Find affordable one-way fares based on user searches. Data last updated August 10, 2026.
This Trip.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1012:27 pm -
Nonstop3h 17m
Deal found 8/5![Allegiant Air logo]()
$90
This Mytrip deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1712:27 pm -
Nonstop3h 17m
Deal found 8/5![Allegiant Air logo]()
$95
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/104:35 pm -
1 stop26h 06m
Deal found 8/5![Multiple Airlines logo]()
$112
This Kiwi.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/297:30 am -
1 stop28h 22m
Deal found 8/6![Multiple Airlines logo]()
$116
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/612:27 pm -
Nonstop3h 17m
Deal found 8/5![Allegiant Air logo]()
$119
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/179:30 am -
1 stop25h 21m
Deal found 8/5![Multiple Airlines logo]()
$123
This Super.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/39:39 am -
1 stop25h 55m
Deal found 8/5![Frontier logo]()
$127
This Super.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/312:27 pm -
Nonstop3h 17m
Deal found 8/5![Allegiant Air logo]()
$133
This Trip.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/104:35 pm -
2 stops24h 58m
Deal found 8/5![Frontier logo]()
$134
Find flight deals from Santa Ana to Des Moines
Discover tips and strategies to find the most affordable flight options for your journey from Santa Ana (SNA) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $126 (Cheapflightsfares) |
One-way from | $90 (Trip.com) |
Popular in | October |
Cheapest in | January |
Average price | $372 |
Good round-trip deal | $166 or less |
Good one-way deal | $100 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Santa Ana to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 10, 2026.
Use the filters below to find and compare flights from Santa Ana to Des Moines that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
Santa AnaDes Moines
SNA Santa Ana J. Wayne/Orange Cnty - DSM Des Moines
SNADSM
Santa Ana J. Wayne/Orange Cnty
Sun 9/6
8:55 am-9:23 pm
2 stops10h 28m
Des Moines
Mon 9/7
5:45 am-9:07 am
1 stop5h 22m
$375
Santa AnaDes Moines
SNA Santa Ana J. Wayne/Orange Cnty - DSM Des Moines
SNADSM
Santa Ana J. Wayne/Orange Cnty
Wed 10/21
7:10 am-9:02 pm
2 stops11h 52m
Des Moines
Fri 10/23
3:03 pm-10:12 pm
1 stop9h 09m
$408
Santa AnaDes Moines
SNA Santa Ana J. Wayne/Orange Cnty - DSM Des Moines
SNADSM
Santa Ana J. Wayne/Orange Cnty
Sat 9/5
12:15 pm-10:37 pm
1 stop8h 22m
Des Moines
Wed 9/9
5:45 am-12:33 pm
1 stop8h 48m
$426
Santa AnaDes Moines
SNA Santa Ana J. Wayne/Orange Cnty - DSM Des Moines
SNADSM
Santa Ana J. Wayne/Orange Cnty
Wed 10/21
11:00 am-8:35 pm
2 stops7h 35m
Des Moines
Fri 10/23
6:20 am-1:00 pm
2 stops8h 40m
$431
Santa AnaDes Moines
SNA Santa Ana J. Wayne/Orange Cnty - DSM Des Moines
SNADSM
Santa Ana J. Wayne/Orange Cnty
Thu 10/22
6:02 pm-10:11 am
2 stops14h 09m
Des Moines
Tue 10/27
3:46 pm-10:05 pm
2 stops8h 19m
$468
Santa AnaDes Moines
SNA Santa Ana J. Wayne/Orange Cnty - DSM Des Moines
SNADSM
Santa Ana J. Wayne/Orange Cnty
Thu 10/22
6:02 pm-10:11 am
2 stops14h 09m
Des Moines
Wed 10/28
10:57 am-6:22 pm
2 stops9h 25m
$468
Santa AnaDes Moines
SNA Santa Ana J. Wayne/Orange Cnty - DSM Des Moines
SNADSM
Santa Ana J. Wayne/Orange Cnty
Sun 9/6
9:00 am-6:15 pm
2 stops7h 15m
Des Moines
Mon 9/7
2:25 pm-9:00 pm
2 stops8h 35m
$500
Santa AnaDes Moines
SNA Santa Ana J. Wayne/Orange Cnty - DSM Des Moines
SNADSM
Santa Ana J. Wayne/Orange Cnty
Wed 11/11
9:53 am-9:13 pm
2 stops9h 20m
Des Moines
Sun 11/15
2:43 pm-8:54 pm
1 stop8h 11m
$502
Santa AnaDes Moines
SNA Santa Ana J. Wayne/Orange Cnty - DSM Des Moines
SNADSM
Santa Ana J. Wayne/Orange Cnty
Sun 9/6
8:55 am-9:23 pm
2 stops10h 28m
Des Moines
Sun 9/13
5:45 am-1:57 pm
2 stops10h 12m
$507
Santa AnaDes Moines
SNA Santa Ana J. Wayne/Orange Cnty - DSM Des Moines
SNADSM
Santa Ana J. Wayne/Orange Cnty
Mon 10/19
6:02 pm-10:11 am
2 stops14h 09m
Des Moines
Sat 10/24
4:01 pm-10:05 pm
2 stops8h 04m
$507
Showing 1-10 of 23 resultsSorted by cheapest first
Compare providers for flights from Santa Ana to Des Moines
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Santa Ana to Des Moines in August.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*1 star | |
| Price Accuracy1 star | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Santa Ana, California-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Santa Ana, California-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Santa Ana, California-Des Moines flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Santa Ana, California-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santa Ana, California-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Santa Ana to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from Santa Ana with our price prediction graph.
SNA-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Santa Ana to Des Moines
What is the cheapest month to book a flight from Santa Ana, California to Des Moines?
Currently, January is the cheapest month in which you can book a flight from Santa Ana, California to Des Moines (average of $175). Flying from Santa Ana, California to Des Moines in October is currently the most expensive (average of $383). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Santa Ana, California to Des Moines?
Airfare is below average for this route at the moment.
Santa Ana, California to Des Moines flights typically cost between $222 and $396 in October.The cheapest round-trip price found within the last 5 days was $126 on Allegiant Air (Oct 22-Oct 25).
Reviews of airlines servicing Des Moines
Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated August 10, 2026.
Read reviews from past customers who have flown United Airlines,Allegiant Air, andAmerican Airlines from Santa Ana to Des Moines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.1
Boarding
7.7
Overall
7.4
Food
6.7
Crew
8.1
Comfort
7.3
Reviews
1 / 20
4.0
OkayDynasty,May 2026
LAX - EWR
Entertainment
7.1
Boarding
7.7
Overall
7.4
Food
6.7
Crew
8.1
Comfort
7.3
Reviews
1 / 20
4.0
OkayDynasty,May 2026
LAX - EWR
Entertainment
7.1
Boarding
7.7
Overall
7.4
Food
6.7
Crew
8.1
Comfort
7.3
Reviews
1 / 20
4.0
OkayDynasty,May 2026
LAX - EWR
Entertainment
7.1
Boarding
7.7
Overall
7.4
Food
6.7
Crew
8.1
Comfort
7.3
Reviews
1 / 20
4.0
OkayDynasty,May 2026
LAX - EWR
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Find useful and relevant information for your journey from Santa Ana to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsAltoona
Clive
Ames
Johnston
Boone
Norwalk
West Des Moines
Ankeny
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Other flights to Des Moines
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Santa Ana and Des Moines flights
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Top 3 airlines flying from Santa Ana to Des Moines
Discover the top 3 airlines that operate flights from Santa Ana to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$141 | Average$198 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$260 | Average$383 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$278 | Average$745 | FlexibilityNo cancel fee | On-time69% |