$68+ Cheap flights from Santa Ana, CA to Des Moines (SNA - DSM)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/15. Fares are subject to change and may not be available on all flights or dates of travel.
SNA — DSM
Dec 5 — Dec 121
Round-trip
1 adult, Economy
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Find cheap flights from Santa Ana to Des Moines with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Santa Ana to Des Moines
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One-way
Cheapest flights from Santa Ana to Des MoinesExplore the most affordable flight options available from Santa Ana to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 5, 2026.
Explore the most affordable flight options available from Santa Ana to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 5, 2026.
This Trip.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2611:42 am -
1 stop5h 51m
Thu 12/38:35 pm -
1 stop16h 48m
Deal found 11/3![Frontier logo]()
$280
This Kiwi.com deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/310:07 am -
2 stops10h 19m
Fri 12/49:18 pm -
1 stop22h 22m
Deal found 10/31![Multiple Airlines logo]()
$284
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/194:01 pm -
1 stop26h 40m
Mon 11/232:50 pm -
Nonstop3h 44m
Deal found 11/4![Multiple Airlines logo]()
$299
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1711:43 am -
2 stops31h 02m
Thu 12/242:21 pm -
1 stop6h 12m
Deal found 11/2![Multiple Airlines logo]()
$301
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/232:54 pm -
1 stop28h 29m
Wed 12/308:13 pm -
1 stop24h 20m
Deal found 11/2![Multiple Airlines logo]()
$321
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/54:50 pm -
Nonstop3h 17m
Mon 11/168:04 pm -
1 stop20h 59m
Deal found 11/2![Multiple Airlines logo]()
$326
This CheapOair deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/154:10 pm -
Nonstop3h 17m
Fri 11/202:50 pm -
Nonstop3h 44m
Deal found 11/2![Allegiant Air logo]()
$339
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/13:28 pm -
1 stop6h 51m
Tue 12/86:05 am -
1 stop8h 25m
Deal found 11/2![American Airlines logo]()
$355
Best flights from Santa Ana to Des MoinesDiscover carefully curated flight deals from Santa Ana to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 5, 2026.
Discover carefully curated flight deals from Santa Ana to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 5, 2026.
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/155:33 pm -
Nonstop3h 21m
Mon 1/187:30 am -
1 stop6h 12m
Deal found 11/4![Multiple Airlines logo]()
$259
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/2510:47 am -
1 stop9h 08m
Wed 12/25:15 pm -
1 stop5h 54m
Deal found 11/3![United Airlines logo]()
$355
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/128:10 am -
1 stop6h 02m
Tue 1/196:45 am -
2 stops12h 58m
Deal found 11/5![Delta logo]()
$360
This Southwest deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/1511:30 am -
2 stops8h 10m
Mon 1/181:50 pm -
2 stops8h 20m
Deal found 11/4![Southwest logo]()
$458
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/312:56 pm -
1 stop6h 35m
Fri 12/410:30 am -
2 stops12h 34m
Deal found 11/3![Delta logo]()
$360
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/267:15 am -
2 stops13h 20m
Thu 12/311:01 am -
2 stops13h 29m
Deal found 11/3![Delta logo]()
$427
This United Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/39:38 am -
2 stops11h 37m
Fri 12/45:15 pm -
1 stop5h 54m
Deal found 10/31![United Airlines logo]()
$470
This Southwest deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/96:45 am -
1 stop6h 45m
Mon 4/121:50 pm -
2 stops8h 05m
Deal found 11/1![Southwest logo]()
$482
This United Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/248:45 am -
2 stops12h 30m
Fri 1/89:25 am -
2 stops13h 19m
Deal found 11/1![United Airlines logo]()
$475
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/166:45 am -
2 stops12h 34m
Sun 1/176:45 am -
2 stops12h 58m
Deal found 11/5![Delta logo]()
$475
Last-minute flights from Santa Ana to Des MoinesDiscover last-minute flight deals from Santa Ana to Des Moines. Data last updated November 5, 2026 and is based on user searches.
Discover last-minute flight deals from Santa Ana to Des Moines. Data last updated November 5, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/54:50 pm -
Nonstop3h 17m
Mon 11/168:04 pm -
1 stop20h 59m
Deal found 11/2![Multiple Airlines logo]()
$326
This CheapOair deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/154:10 pm -
Nonstop3h 17m
Fri 11/202:50 pm -
Nonstop3h 44m
Deal found 11/2![Allegiant Air logo]()
$339
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/194:01 pm -
1 stop26h 40m
Mon 11/232:50 pm -
Nonstop3h 44m
Deal found 11/4![Multiple Airlines logo]()
$299
This Trip.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2611:42 am -
1 stop5h 51m
Thu 12/38:35 pm -
1 stop16h 48m
Deal found 11/3![Frontier logo]()
$280
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/13:28 pm -
1 stop6h 51m
Tue 12/86:05 am -
1 stop8h 25m
Deal found 11/2![American Airlines logo]()
$355
This Kiwi.com deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/310:07 am -
2 stops10h 19m
Fri 12/49:18 pm -
1 stop22h 22m
Deal found 10/31![Multiple Airlines logo]()
$284
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1711:43 am -
2 stops31h 02m
Thu 12/242:21 pm -
1 stop6h 12m
Deal found 11/2![Multiple Airlines logo]()
$301
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/232:54 pm -
1 stop28h 29m
Wed 12/308:13 pm -
1 stop24h 20m
Deal found 11/2![Multiple Airlines logo]()
$321
One-way flights from Santa Ana to Des MoinesSearch for one-way flight options from Santa Ana to Des Moines. Find affordable one-way fares based on user searches. Data last updated November 5, 2026.
Search for one-way flight options from Santa Ana to Des Moines. Find affordable one-way fares based on user searches. Data last updated November 5, 2026.
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/155:33 pm -
Nonstop3h 21m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![Allegiant Air logo]()
$68
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/2610:10 am -
Nonstop3h 19m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![Allegiant Air logo]()
$139
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/79:38 am -
Nonstop3h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![Allegiant Air logo]()
$147
This Super.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/612:33 pm -
1 stop5h 17m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![Frontier logo]()
$154
This Frontier deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/2411:46 am -
1 stop5h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![Frontier logo]()
$157
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/38:55 pm -
1 stop24h 11m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![Allegiant Air logo]()
$169
This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/2512:05 pm -
1 stop8h 33m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![Delta logo]()
$178
This CheapOair deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/124:50 pm -
Nonstop3h 17m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![Allegiant Air logo]()
$184
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/278:55 pm -
1 stop24h 11m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![Allegiant Air logo]()
$186
This Cheapflightsfares deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/1311:38 am -
1 stop5h 57m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![Frontier logo]()
$198
This Super.com deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/154:10 pm -
Nonstop3h 17m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/31![Allegiant Air logo]()
$208
Find flight deals from Santa Ana to Des Moines
Discover tips and strategies to find the most affordable flight options for your journey from Santa Ana (SNA) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 5, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $119 (Cheapflightsfares) |
One-way from | $68 (Kiwi.com) |
Popular in | November |
Cheapest in | January |
Average price | $462 |
Cheapflights Fare Finder
Customize your flight search to find flights from Santa Ana to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 5, 2026.
Use the filters below to find and compare flights from Santa Ana to Des Moines that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
Santa AnaDes Moines
SNA Santa Ana J. Wayne/Orange Cnty - DSM Des Moines
SNADSM
Santa Ana J. Wayne/Orange Cnty
Sat 12/26
10:10 am-3:29 pm
Nonstop3h 19m
Des Moines
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$139
Santa AnaDes Moines
SNA Santa Ana J. Wayne/Orange Cnty - DSM Des Moines
SNADSM
Santa Ana J. Wayne/Orange Cnty
Sun 1/3
8:55 pm-11:06 pm
1 stop24h 11m
Des Moines
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$173
Santa AnaDes Moines
SNA Santa Ana J. Wayne/Orange Cnty - DSM Des Moines
SNADSM
Santa Ana J. Wayne/Orange Cnty
Fri 12/25
12:05 pm-10:38 pm
1 stop8h 33m
Des Moines
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$178
Santa AnaDes Moines
SNA Santa Ana J. Wayne/Orange Cnty - DSM Des Moines
SNADSM
Santa Ana J. Wayne/Orange Cnty
Fri 1/15
11:35 am-9:40 pm
2 stops8h 05m
Des Moines
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$210
Santa AnaDes Moines
SNA Santa Ana J. Wayne/Orange Cnty - DSM Des Moines
SNADSM
Santa Ana J. Wayne/Orange Cnty
Fri 12/25
9:51 am-11:08 pm
2 stops11h 17m
Des Moines
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$223
Santa AnaDes Moines
SNA Santa Ana J. Wayne/Orange Cnty - DSM Des Moines
SNADSM
Santa Ana J. Wayne/Orange Cnty
Wed 11/18
3:42 pm-8:41 pm
2 stops50h 59m
Des Moines
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$229
Santa AnaDes Moines
SNA Santa Ana J. Wayne/Orange Cnty - DSM Des Moines
SNADSM
Santa Ana J. Wayne/Orange Cnty
Tue 12/29
6:48 am-4:16 pm
1 stop7h 28m
Des Moines
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$233
Santa AnaDes Moines
SNA Santa Ana J. Wayne/Orange Cnty - DSM Des Moines
SNADSM
Santa Ana J. Wayne/Orange Cnty
Fri 1/1
8:45 am-4:16 pm
1 stop5h 31m
Des Moines
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$233
Santa AnaDes Moines
SNA Santa Ana J. Wayne/Orange Cnty - DSM Des Moines
SNADSM
Santa Ana J. Wayne/Orange Cnty
Sun 3/7
7:05 pm-10:20 am
2 stops13h 15m
Des Moines
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$244
Santa AnaDes Moines
SNA Santa Ana J. Wayne/Orange Cnty - DSM Des Moines
SNADSM
Santa Ana J. Wayne/Orange Cnty
Fri 1/15
5:33 pm-10:54 pm
Nonstop3h 21m
Des Moines
Mon 1/18
7:30 am-11:42 am
1 stop6h 12m
$259
Showing 1-10 of 20 resultsSorted by cheapest first
Compare providers for flights from Santa Ana to Des Moines
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Santa Ana to Des Moines in November.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*1 star | |
| Price Accuracy1 star | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Santa Ana, California-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Santa Ana, California-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Santa Ana, California-Des Moines flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Santa Ana, California-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santa Ana, California-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Santa Ana to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from Santa Ana with our price prediction graph.
SNA-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Santa Ana to Des Moines
What is the cheapest month to book a flight from Santa Ana, California to Des Moines?
Currently, January is the cheapest month in which you can book a flight from Santa Ana, California to Des Moines (average of $175). Flying from Santa Ana, California to Des Moines in November is currently the most expensive (average of $462). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Santa Ana, California to Des Moines?
Airfare is below average for this route at the moment.
Santa Ana, California to Des Moines flights typically cost between $283 and $926 in January.The cheapest round-trip price found within the last 5 days was $119 on Allegiant Air (Jan 15-Jan 18).
Reviews of airlines servicing Des Moines
Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated November 5, 2026.
Read reviews from past customers who have flown United Airlines,Allegiant Air, andAmerican Airlines from Santa Ana to Des Moines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.3
Crew
8.1
Food
6.7
Boarding
7.7
Entertainment
7.1
Overall
7.3
Reviews
1 / 20
4.0
OkayDynasty,May 2026
LAX - EWR
Comfort
7.3
Crew
8.1
Food
6.7
Boarding
7.7
Entertainment
7.1
Overall
7.3
Reviews
1 / 20
4.0
OkayDynasty,May 2026
LAX - EWR
Comfort
7.3
Crew
8.1
Food
6.7
Boarding
7.7
Entertainment
7.1
Overall
7.3
Reviews
1 / 20
4.0
OkayDynasty,May 2026
LAX - EWR
Comfort
7.3
Crew
8.1
Food
6.7
Boarding
7.7
Entertainment
7.1
Overall
7.3
Reviews
1 / 20
4.0
OkayDynasty,May 2026
LAX - EWR
Related info for your journey
Find useful and relevant information for your journey from Santa Ana to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsAltoona
Clive
West Des Moines
Ames
Johnston
Boone
Norwalk
Ankeny
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Alternative routes for Santa Ana to Des Moines
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Other flights to Des Moines
Explore flights to Des Moines departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on November 5, 2026.
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Santa Ana and Des Moines flights
Browse other Santa Ana and Des Moines flight options. Last updated on November 5, 2026.
Other flights from Santa Ana
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Top 3 airlines flying from Santa Ana to Des Moines
Discover the top 3 airlines that operate flights from Santa Ana to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 5, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$141 | Average$206 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$300 | Average$436 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$346 | Average$775 | FlexibilityNo cancel fee | On-time69% |