$38+ Cheap flights from Fort Myers to Des Moines (RSW - DSM)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/6. Fares are subject to change and may not be available on all flights or dates of travel.
RSW — DSM
Nov 24 — Dec 11
Round-trip
1 adult, Economy
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Find cheap flights from Fort Myers to Des Moines with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Fort Myers to Des Moines
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Cheapest flights from Fort Myers to Des MoinesExplore the most affordable flight options available from Fort Myers to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 25, 2026.
Explore the most affordable flight options available from Fort Myers to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 25, 2026.
This CheapOair deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/47:53 pm -
Nonstop3h 28m
Mon 12/73:05 pm -
Nonstop2h 58m
Deal found 10/25![Allegiant Air logo]()
$76
This Booking.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/252:21 pm -
Nonstop3h 12m
Sun 11/299:30 am -
Nonstop3h 01m
Deal found 10/21![Allegiant Air logo]()
$210
This Kiwi.com deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/47:53 pm -
Nonstop3h 28m
Mon 12/710:40 am -
3 stops31h 08m
Deal found 10/25![Multiple Airlines logo]()
$264
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:24 pm -
1 stop6h 02m
Mon 11/168:07 am -
1 stop4h 48m
Deal found 10/20![American Airlines logo]()
$293
This Southwest deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1111:55 am -
2 stops11h 10m
Mon 11/163:30 pm -
1 stop5h 50m
Deal found 10/20![Southwest logo]()
$298
This Kiwi.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/68:00 pm -
Nonstop3h 15m
Sun 11/812:25 pm -
2 stops33h 46m
Deal found 10/21![Multiple Airlines logo]()
$332
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/254:54 pm -
1 stop7h 29m
Fri 11/275:23 am -
1 stop7h 14m
Deal found 10/21![American Airlines logo]()
$334
This Kiwi.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/255:48 pm -
1 stop26h 45m
Sun 11/299:30 am -
Nonstop3h 01m
Deal found 10/21![Multiple Airlines logo]()
$361
Best flights from Fort Myers to Des MoinesDiscover carefully curated flight deals from Fort Myers to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 25, 2026.
Discover carefully curated flight deals from Fort Myers to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 25, 2026.
This Delta deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/134:15 pm -
1 stop5h 37m
Tue 1/1910:15 am -
1 stop6h 07m
Deal found 10/23![Delta logo]()
$293
This Kiwi.com deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/47:53 pm -
Nonstop3h 28m
Mon 12/77:20 am -
2 stops26h 35m
Deal found 10/25![Multiple Airlines logo]()
$311
This Southwest deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1111:55 am -
2 stops11h 10m
Mon 11/166:00 am -
2 stops10h 00m
Deal found 10/20![Southwest logo]()
$322
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/254:45 pm -
1 stop6h 10m
Sun 11/296:05 am -
1 stop6h 03m
Deal found 10/21![United Airlines logo]()
$375
This Kiwi.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/255:48 pm -
1 stop26h 45m
Sun 11/299:30 am -
Nonstop3h 01m
Deal found 10/21![Multiple Airlines logo]()
$361
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/218:00 am -
1 stop9h 11m
Mon 1/259:00 am -
1 stop9h 40m
Deal found 10/20![United Airlines logo]()
$403
This Southwest deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/211:45 am -
2 stops10h 50m
Fri 3/56:45 am -
1 stop12h 15m
Deal found 10/23![Southwest logo]()
$417
Last-minute flights from Fort Myers to Des MoinesDiscover last-minute flight deals from Fort Myers to Des Moines. Data last updated October 25, 2026 and is based on user searches.
Discover last-minute flight deals from Fort Myers to Des Moines. Data last updated October 25, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/68:00 pm -
Nonstop3h 15m
Sun 11/812:25 pm -
2 stops33h 46m
Deal found 10/21![Multiple Airlines logo]()
$332
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:24 pm -
1 stop6h 02m
Mon 11/168:07 am -
1 stop4h 48m
Deal found 10/20![American Airlines logo]()
$293
This Southwest deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1111:55 am -
2 stops11h 10m
Mon 11/163:30 pm -
1 stop5h 50m
Deal found 10/20![Southwest logo]()
$298
This KAYAK deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/164:54 pm -
1 stop7h 11m
Thu 11/196:06 am -
1 stop8h 16m
Deal found 10/22![American Airlines logo]()
$433
This United Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/202:15 pm -
1 stop8h 40m
Tue 11/243:01 pm -
1 stop7h 12m
Deal found 10/23![United Airlines logo]()
$416
This Booking.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/252:21 pm -
Nonstop3h 12m
Sun 11/299:30 am -
Nonstop3h 01m
Deal found 10/21![Allegiant Air logo]()
$210
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/254:54 pm -
1 stop7h 29m
Fri 11/275:23 am -
1 stop7h 14m
Deal found 10/21![American Airlines logo]()
$334
This Kiwi.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/255:48 pm -
1 stop26h 45m
Sun 11/299:30 am -
Nonstop3h 01m
Deal found 10/21![Multiple Airlines logo]()
$361
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/254:45 pm -
1 stop6h 10m
Sun 11/296:05 am -
1 stop6h 03m
Deal found 10/21![United Airlines logo]()
$375
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/251:05 pm -
2 stops9h 50m
Fri 11/278:00 am -
1 stop5h 49m
Deal found 10/21![United Airlines logo]()
$400
One-way flights from Fort Myers to Des MoinesSearch for one-way flight options from Fort Myers to Des Moines. Find affordable one-way fares based on user searches. Data last updated October 25, 2026.
Search for one-way flight options from Fort Myers to Des Moines. Find affordable one-way fares based on user searches. Data last updated October 25, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/68:00 pm -
Nonstop3h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Allegiant Air logo]()
$38
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/217:38 pm -
Nonstop3h 26m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![Allegiant Air logo]()
$76
This Kiwi.com deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/307:53 pm -
Nonstop3h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/24![Allegiant Air logo]()
$83
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/106:24 pm -
1 stop6h 02m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![American Airlines logo]()
$147
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/97:00 am -
2 stops10h 11m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![United Airlines logo]()
$152
This Kiwi.com deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/127:16 pm -
Nonstop3h 33m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/24![Allegiant Air logo]()
$162
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/912:35 pm -
2 stops10h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![United Airlines logo]()
$171
This United Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/124:36 pm -
1 stop7h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/24![United Airlines logo]()
$178
This Southwest deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/2012:35 pm -
2 stops10h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Southwest logo]()
$201
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/1812:52 pm -
1 stop7h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![American Airlines logo]()
$202
Find flight deals from Fort Myers to Des Moines
Discover tips and strategies to find the most affordable flight options for your journey from Fort Myers (RSW) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 25, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $76 (CheapOair) |
One-way from | $38 (Kiwi.com) |
Popular in | March |
Cheapest in | December |
Average price | $384 |
Cheapflights Fare Finder
Customize your flight search to find flights from Fort Myers to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 25, 2026.
Use the filters below to find and compare flights from Fort Myers to Des Moines that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
Fort MyersDes Moines
RSW Fort Myers SW Florida Intl - DSM Des Moines
RSWDSM
Fort Myers SW Florida Intl
Sat 1/9
6:50 am-12:13 pm
1 stop6h 23m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$147
Fort MyersDes Moines
RSW Fort Myers SW Florida Intl - DSM Des Moines
RSWDSM
Fort Myers SW Florida Intl
Tue 1/12
8:00 am-4:11 pm
1 stop9h 11m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$147
Fort MyersDes Moines
RSW Fort Myers SW Florida Intl - DSM Des Moines
RSWDSM
Fort Myers SW Florida Intl
Mon 12/21
1:30 pm-8:45 pm
1 stop8h 15m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$147
Fort MyersDes Moines
RSW Fort Myers SW Florida Intl - DSM Des Moines
RSWDSM
Fort Myers SW Florida Intl
Wed 12/23
11:28 am-6:03 pm
1 stop7h 35m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$147
Fort MyersDes Moines
RSW Fort Myers SW Florida Intl - DSM Des Moines
RSWDSM
Fort Myers SW Florida Intl
Sat 1/9
8:15 am-5:35 pm
2 stops10h 20m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$152
Fort MyersDes Moines
RSW Fort Myers SW Florida Intl - DSM Des Moines
RSWDSM
Fort Myers SW Florida Intl
Mon 11/9
12:35 pm-9:55 pm
2 stops10h 20m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$171
Fort MyersDes Moines
RSW Fort Myers SW Florida Intl - DSM Des Moines
RSWDSM
Fort Myers SW Florida Intl
Tue 11/10
7:06 am-7:16 pm
2 stops13h 10m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$207
Fort MyersDes Moines
RSW Fort Myers SW Florida Intl - DSM Des Moines
RSWDSM
Fort Myers SW Florida Intl
Wed 1/13
4:15 pm-8:52 pm
1 stop5h 37m
Des Moines
Tue 1/19
10:15 am-5:22 pm
1 stop6h 07m
$293
Fort MyersDes Moines
RSW Fort Myers SW Florida Intl - DSM Des Moines
RSWDSM
Fort Myers SW Florida Intl
Fri 12/4
7:53 pm-10:21 pm
Nonstop3h 28m
Des Moines
Mon 12/7
7:20 am-10:55 am
2 stops26h 35m
$311
Fort MyersDes Moines
RSW Fort Myers SW Florida Intl - DSM Des Moines
RSWDSM
Fort Myers SW Florida Intl
Wed 11/11
11:55 am-10:05 pm
2 stops11h 10m
Des Moines
Mon 11/16
6:00 am-5:00 pm
2 stops10h 00m
$322
Showing 1-10 of 14 resultsSorted by cheapest first
Compare providers for flights from Fort Myers to Des Moines
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Fort Myers to Des Moines in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Fort Myers-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Fort Myers-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Fort Myers-Des Moines flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Fort Myers-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Fort Myers-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Fort Myers to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from Fort Myers with our price prediction graph.
RSW-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Fort Myers to Des Moines
What is the cheapest month to book a flight from Fort Myers to Des Moines?
Currently, December is the cheapest month in which you can book a flight from Fort Myers to Des Moines (average of $140). Flying from Fort Myers to Des Moines in March is currently the most expensive (average of $508). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from RSW to DSM?
Find hourly flight availability from Fort Myers to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 25, 2026.
One of the essential ways to save on airfare from Fort Myers to Des Moines is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight in the evening could potentially save you up to 78% on airfare.
Reviews of airlines servicing Des Moines
Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated October 25, 2026.
Peruse reviews from past customers who have flown with Delta,Allegiant Air, andAmerican Airlines from Fort Myers to Des Moines to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Entertainment
7.8
Boarding
8.1
Food
7.2
Overall
7.8
Comfort
7.8
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Crew
8.5
Entertainment
7.8
Boarding
8.1
Food
7.2
Overall
7.8
Comfort
7.8
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Crew
8.5
Entertainment
7.8
Boarding
8.1
Food
7.2
Overall
7.8
Comfort
7.8
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Crew
8.5
Entertainment
7.8
Boarding
8.1
Food
7.2
Overall
7.8
Comfort
7.8
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Related info for your journey
Find useful and relevant information for your journey from Fort Myers to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsAltoona
Clive
West Des Moines
Ames
Johnston
Boone
Norwalk
Ankeny
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Other flights to Des Moines
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Fort Myers and Des Moines flights
Browse other Fort Myers and Des Moines flight options. Last updated on October 25, 2026.
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Top 3 airlines flying from Fort Myers to Des Moines
Discover the top 3 airlines that operate flights from Fort Myers to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 25, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$94 | Average$140 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$152 | Average$428 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$236 | Average$441 | FlexibilityNo cancel fee | On-time71% |