$65+ Cheap flights from Des Moines to Fort Myers (DSM - RSW)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/21. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — RSW
Oct 12 — Oct 191
Round-trip
1 adult, Economy
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Find cheap flights from Des Moines to Fort Myers with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Des Moines to Fort Myers SW Florida Intl are usually found in September or April, booked 19 days in advance, depart on a Monday or Wednesday and return on a Tuesday
Cheap flight deals from Des Moines to Fort Myers
Cheapest
Best
Last-minute
One-way
Cheapest flights from Des Moines to Fort MyersExplore the most affordable flight options available from Des Moines to Fort Myers. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 12, 2026.
Explore the most affordable flight options available from Des Moines to Fort Myers. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 12, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/22:56 pm -
Nonstop2h 59m
Fri 11/68:00 pm -
Nonstop3h 15m
Deal found 9/7![Allegiant Air logo]()
$144
This CheapOair deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/183:04 pm -
Nonstop2h 59m
Fri 9/257:53 pm -
Nonstop3h 15m
Deal found 9/11![Allegiant Air logo]()
$157
This CheapOair deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/262:49 pm -
Nonstop2h 59m
Mon 11/27:45 pm -
Nonstop3h 15m
Deal found 9/7![Allegiant Air logo]()
$158
This CheapOair deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/192:49 pm -
Nonstop2h 59m
Mon 10/267:38 pm -
Nonstop3h 15m
Deal found 9/7![Allegiant Air logo]()
$163
This CheapOair deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/303:04 pm -
Nonstop2h 59m
Mon 11/27:45 pm -
Nonstop3h 15m
Deal found 9/10![Allegiant Air logo]()
$164
This CheapOair deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/1410:05 am -
Nonstop2h 59m
Fri 9/187:53 pm -
Nonstop3h 15m
Deal found 9/10![Allegiant Air logo]()
$185
This CheapOair deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/92:41 pm -
Nonstop2h 59m
Mon 11/167:30 pm -
Nonstop3h 15m
Deal found 9/7![Allegiant Air logo]()
$209
This CheapOair deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/133:11 pm -
Nonstop2h 59m
Mon 11/167:30 pm -
Nonstop3h 15m
Deal found 9/9![Allegiant Air logo]()
$231
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/93:04 pm -
Nonstop2h 59m
Mon 10/127:38 pm -
Nonstop3h 15m
Deal found 9/11![Allegiant Air logo]()
$235
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/18:00 am -
1 stop26h 54m
Fri 11/68:00 pm -
Nonstop3h 15m
Deal found 9/7![Multiple Airlines logo]()
$240
This CheapOair deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/113:04 pm -
Nonstop2h 59m
Mon 9/142:54 pm -
Nonstop3h 15m
Deal found 9/8![Allegiant Air logo]()
$242
Best flights from Des Moines to Fort MyersDiscover carefully curated flight deals from Des Moines to Fort Myers that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 12, 2026.
Discover carefully curated flight deals from Des Moines to Fort Myers that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 12, 2026.
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/193:46 pm -
1 stop6h 35m
Mon 10/262:15 pm -
1 stop7h 25m
Deal found 9/9![Delta logo]()
$339
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/273:00 pm -
1 stop5h 49m
Sat 3/64:35 pm -
1 stop7h 21m
Deal found 9/10![United Airlines logo]()
$388
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/134:25 pm -
1 stop5h 05m
Sun 11/156:10 am -
2 stops8h 00m
Deal found 9/10![Southwest logo]()
$428
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/206:52 pm -
1 stop4h 48m
Mon 11/237:00 am -
1 stop8h 08m
Deal found 9/7![Delta logo]()
$430
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/211:33 am -
1 stop9h 26m
Fri 10/162:14 pm -
1 stop8h 09m
Deal found 9/8![United Airlines logo]()
$459
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/275:20 am -
2 stops11h 10m
Fri 3/55:30 am -
2 stops10h 00m
Deal found 9/10![Southwest logo]()
$460
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/181:27 pm -
2 stops8h 46m
Sun 11/228:00 am -
1 stop9h 07m
Deal found 9/8![United Airlines logo]()
$493
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/206:42 pm -
1 stop5h 01m
Sun 12/274:45 pm -
1 stop6h 53m
Deal found 9/8![Delta logo]()
$497
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/98:00 am -
1 stop8h 15m
Tue 1/124:45 pm -
1 stop6h 45m
Deal found 9/11![United Airlines logo]()
$493
This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/164:00 pm -
1 stop5h 54m
Mon 1/184:10 pm -
1 stop6h 14m
Deal found 9/12![Delta logo]()
$538
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/91:45 pm -
1 stop8h 23m
Mon 1/119:00 am -
2 stops12h 32m
Deal found 9/11![United Airlines logo]()
$498
Last-minute flights from Des Moines to Fort MyersDiscover last-minute flight deals from Des Moines to Fort Myers. Data last updated September 12, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Fort Myers. Data last updated September 12, 2026 and is based on user searches.
This CheapOair deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/113:04 pm -
Nonstop2h 59m
Mon 9/142:54 pm -
Nonstop3h 15m
Deal found 9/8![Allegiant Air logo]()
$242
This CheapOair deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/1410:05 am -
Nonstop2h 59m
Fri 9/187:53 pm -
Nonstop3h 15m
Deal found 9/10![Allegiant Air logo]()
$185
This CheapOair deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/183:04 pm -
Nonstop2h 59m
Fri 9/257:53 pm -
Nonstop3h 15m
Deal found 9/11![Allegiant Air logo]()
$157
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/253:04 pm -
Nonstop2h 59m
Wed 9/307:00 am -
3 stops32h 10m
Deal found 9/9![Multiple Airlines logo]()
$264
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/93:04 pm -
Nonstop2h 59m
Mon 10/127:38 pm -
Nonstop3h 15m
Deal found 9/11![Allegiant Air logo]()
$235
This Mytrip deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/163:04 pm -
Nonstop2h 59m
Mon 10/197:38 pm -
Nonstop3h 15m
Deal found 9/9![Allegiant Air logo]()
$243
This CheapOair deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/192:49 pm -
Nonstop2h 59m
Mon 10/267:38 pm -
Nonstop3h 15m
Deal found 9/7![Allegiant Air logo]()
$163
This CheapOair deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/262:49 pm -
Nonstop2h 59m
Mon 11/27:45 pm -
Nonstop3h 15m
Deal found 9/7![Allegiant Air logo]()
$158
This CheapOair deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/303:04 pm -
Nonstop2h 59m
Mon 11/27:45 pm -
Nonstop3h 15m
Deal found 9/10![Allegiant Air logo]()
$164
One-way flights from Des Moines to Fort MyersSearch for one-way flight options from Des Moines to Fort Myers. Find affordable one-way fares based on user searches. Data last updated September 12, 2026.
Search for one-way flight options from Des Moines to Fort Myers. Find affordable one-way fares based on user searches. Data last updated September 12, 2026.
This Super.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2110:05 am -
Nonstop2h 59m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![Allegiant Air logo]()
$65
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/298:03 am -
1 stop5h 01m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![American Airlines logo]()
$170
This Southwest deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/292:40 pm -
2 stops6h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Southwest logo]()
$175
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/201:58 pm -
1 stop18h 23m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![Multiple Airlines logo]()
$192
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/18:00 am -
1 stop26h 54m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Multiple Airlines logo]()
$193
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/176:17 pm -
1 stop5h 21m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![American Airlines logo]()
$202
This Southwest deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/175:25 am -
2 stops9h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Southwest logo]()
$217
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/137:06 am -
1 stop6h 29m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![American Airlines logo]()
$219
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/182:50 pm -
Nonstop2h 58m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Allegiant Air logo]()
$221
Find flight deals from Des Moines to Fort Myers
Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Fort Myers (RSW). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 12, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $144 (Kiwi.com) |
One-way from | $65 (Super.com) |
Popular in | August |
Cheapest in | September |
Average price | $135 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Fort Myers that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 12, 2026.
Use the filters below to find and compare flights from Des Moines to Fort Myers that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesFort Myers
DSM Des Moines - RSW Fort Myers SW Florida Intl
DSMRSW
Des Moines
Mon 9/21
10:05 am-2:04 pm
Nonstop2h 59m
Fort Myers SW Florida Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$65
Des MoinesFort Myers
DSM Des Moines - RSW Fort Myers SW Florida Intl
DSMRSW
Des Moines
Thu 12/17
5:25 am-3:55 pm
2 stops9h 30m
Fort Myers SW Florida Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$217
Quickest round-trip
Des MoinesFort Myers
DSM Des Moines - RSW Fort Myers SW Florida Intl
DSMRSW
Des Moines
Fri 12/18
2:50 pm-6:48 pm
Nonstop2h 58m
Fort Myers SW Florida Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$221
Des MoinesFort Myers
DSM Des Moines - RSW Fort Myers SW Florida Intl
DSMRSW
Des Moines
Thu 10/22
7:10 pm-8:45 am
2 stops12h 35m
Fort Myers SW Florida Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$223
Des MoinesFort Myers
DSM Des Moines - RSW Fort Myers SW Florida Intl
DSMRSW
Des Moines
Sun 12/13
5:25 am-3:55 pm
2 stops9h 30m
Fort Myers SW Florida Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$234
Des MoinesFort Myers
DSM Des Moines - RSW Fort Myers SW Florida Intl
DSMRSW
Des Moines
Mon 10/19
5:10 am-1:45 pm
2 stops7h 35m
Fort Myers SW Florida Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$234
Des MoinesFort Myers
DSM Des Moines - RSW Fort Myers SW Florida Intl
DSMRSW
Des Moines
Fri 11/20
3:08 pm-7:09 pm
Nonstop3h 01m
Fort Myers SW Florida Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$243
Des MoinesFort Myers
DSM Des Moines - RSW Fort Myers SW Florida Intl
DSMRSW
Des Moines
Fri 10/2
6:00 am-2:57 pm
1 stop7h 57m
Fort Myers SW Florida Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$247
Des MoinesFort Myers
DSM Des Moines - RSW Fort Myers SW Florida Intl
DSMRSW
Des Moines
Thu 10/1
6:00 am-1:01 pm
1 stop6h 01m
Fort Myers SW Florida Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$247
Des MoinesFort Myers
DSM Des Moines - RSW Fort Myers SW Florida Intl
DSMRSW
Des Moines
Fri 11/20
6:52 pm-12:40 am
1 stop4h 48m
Fort Myers SW Florida Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$259
Showing 1-10 of 22 resultsSorted by cheapest first
Compare providers for flights from Des Moines to Fort Myers
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Fort Myers in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Des Moines-Fort Myers flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Fort Myers flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Fort Myers flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Des Moines-Fort Myers flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Fort Myers flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Des Moines to Fort Myers
Have a flexible travel schedule? Discover the best time to fly to Fort Myers from Des Moines with our price prediction graph.
DSM-RSW
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Fort Myers
How far ahead should I book a flight from Des Moines to Fort Myers?
The price you pay for your flight from Des Moines to Fort Myers may vary depending on when you book. For the best chance of a lower fare, look to book 18 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Des Moines to Fort Myers?
Currently, September is the cheapest month in which you can book a flight from Des Moines to Fort Myers (average of $135). Flying from Des Moines to Fort Myers in August is currently the most expensive (average of $389). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from DSM to RSW?
Find hourly flight availability from Des Moines to Fort Myers. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 12, 2026.
When flying from Des Moines to Fort Myers, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
Reviews of airlines servicing Fort Myers
Get insights into the airlines that provide service to Fort Myers. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Fort Myers. Reviews last updated September 12, 2026.
Read reviews from past customers who have flown Southwest,Delta, andUnited Airlines from Des Moines to Fort Myers. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Overall
8.0
Comfort
8.0
Crew
8.6
Food
7.0
Entertainment
7.5
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Boarding
8.1
Overall
8.0
Comfort
8.0
Crew
8.6
Food
7.0
Entertainment
7.5
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Boarding
8.1
Overall
8.0
Comfort
8.0
Crew
8.6
Food
7.0
Entertainment
7.5
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Boarding
8.1
Overall
8.0
Comfort
8.0
Crew
8.6
Food
7.0
Entertainment
7.5
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Boarding
8.1
Overall
8.0
Comfort
8.0
Crew
8.6
Food
7.0
Entertainment
7.5
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Boarding
8.1
Overall
8.0
Comfort
8.0
Crew
8.6
Food
7.0
Entertainment
7.5
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Fort Myers. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Fort Myers?
Book flights to Fort Myers if you plan to visit one of these locationsNorth Fort Myers
Lehigh Acres
Sanibel
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Des Moines and Fort Myers flights
Browse other Des Moines and Fort Myers flight options. Last updated on September 12, 2026.
Other flights from Des Moines
Browse through other flights departing from Des Moines. Flights are based on user searches made on Cheapflights and were last updated on September 12, 2026.
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Top 5 airlines flying from Des Moines to Fort Myers
Discover the top 5 airlines that operate flights from Des Moines to Fort Myers. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 12, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$91 | Average$211 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$169 | Average$404 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$260 | Average$382 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$286 | Average$406 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$300 | Average$426 | FlexibilityNo cancel fee | On-time63% |