$138+ Cheap flights from Des Moines to Fort Myers (DSM - RSW)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/16. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — RSW
Jul 12 — Jul 191
Round-trip
1 adult, Economy
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Find cheap flights from Des Moines to Fort Myers with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Des Moines to Fort Myers SW Florida Intl are usually found in May or April, booked 19 days in advance, depart on a Monday or Tuesday and return on a Monday
Cheap flight deals from Des Moines to Fort Myers
Cheapest
Best
Last-minute
One-way
Cheapest flights from Des Moines to Fort MyersExplore the most affordable flight options available from Des Moines to Fort Myers. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2026.
Explore the most affordable flight options available from Des Moines to Fort Myers. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2026.
This Delta deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/46:35 pm
DSM
- RSW
1 stop5h 05m
Delta
Wed 8/125:35 am
RSW
- DSM
1 stop6h 08m
Delta
Deal found 6/12![Delta logo]()
$333
This Southwest deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/1512:10 pm
DSM
- RSW
1 stop5h 40m
Southwest
Mon 8/173:40 pm
RSW
- DSM
2 stops7h 30m
Southwest
Deal found 6/11![Southwest logo]()
$338
This Delta deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/46:35 pm
DSM
- RSW
1 stop5h 05m
Delta
Mon 8/103:04 pm
RSW
- DSM
1 stop6h 55m
Delta
Deal found 6/12![Delta logo]()
$354
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/83:45 pm
DSM
- RSW
1 stop6h 00m
Southwest
Tue 7/147:10 am
RSW
- DSM
1 stop5h 20m
Southwest
Deal found 6/8![Southwest logo]()
$359
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/88:53 am
DSM
- RSW
2 stops10h 40m
American Airlines
Tue 7/145:24 pm
RSW
- DSM
1 stop7h 37m
American Airlines
Deal found 6/10![American Airlines logo]()
$372
This Delta deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/66:35 pm
DSM
- RSW
1 stop5h 05m
Delta
Mon 8/103:04 pm
RSW
- DSM
1 stop6h 55m
Delta
Deal found 6/12![Delta logo]()
$375
This Delta deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/14:47 pm
DSM
- RSW
1 stop6h 36m
Delta
Wed 8/125:35 am
RSW
- DSM
1 stop6h 08m
Delta
Deal found 6/12![Delta logo]()
$380
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/142:29 pm
DSM
- RSW
1 stop7h 40m
American Airlines
Sat 9/198:54 am
RSW
- DSM
2 stops11h 27m
American Airlines
Deal found 6/10![American Airlines logo]()
$388
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/73:45 pm
DSM
- RSW
1 stop6h 00m
Southwest
Mon 7/135:10 am
RSW
- DSM
1 stop7h 20m
Southwest
Deal found 6/8![Southwest logo]()
$393
This United Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:00 am
DSM
- RSW
1 stop6h 01m
United Airlines
Wed 10/74:09 pm
RSW
- DSM
1 stop8h 50m
United Airlines
Deal found 6/8![United Airlines logo]()
$394
Best flights from Des Moines to Fort MyersDiscover carefully curated flight deals from Des Moines to Fort Myers that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 12, 2026.
Discover carefully curated flight deals from Des Moines to Fort Myers that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 12, 2026.
This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/156:55 am
DSM
- RSW
1 stop5h 38m
Delta
Mon 8/1711:00 am
RSW
- DSM
1 stop7h 50m
Delta
Deal found 6/11![Delta logo]()
$333
This United Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/56:00 am
DSM
- RSW
1 stop7h 44m
United Airlines
Mon 8/104:39 pm
RSW
- DSM
1 stop7h 17m
United Airlines
Deal found 6/11![United Airlines logo]()
$441
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/35:10 am
DSM
- RSW
2 stops10h 20m
Southwest
Fri 8/73:40 pm
RSW
- DSM
2 stops7h 30m
Southwest
Deal found 6/8![Southwest logo]()
$453
This Delta deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/236:37 pm
DSM
- RSW
1 stop4h 46m
Delta
Mon 7/276:27 pm
RSW
- DSM
1 stop5h 02m
Delta
Deal found 6/12![Delta logo]()
$427
This United Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/295:45 am
DSM
- RSW
1 stop8h 42m
United Airlines
Wed 9/24:40 pm
RSW
- DSM
1 stop5h 43m
United Airlines
Deal found 6/12![United Airlines logo]()
$444
This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/262:45 pm
DSM
- RSW
1 stop8h 13m
Delta
Tue 7/76:45 am
RSW
- DSM
1 stop7h 49m
Delta
Deal found 6/11![Delta logo]()
$433
This United Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:00 am
DSM
- RSW
1 stop6h 01m
United Airlines
Wed 10/712:16 pm
RSW
- DSM
2 stops10h 07m
United Airlines
Deal found 6/12![United Airlines logo]()
$449
This United Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/1411:23 am
DSM
- RSW
1 stop8h 11m
United Airlines
Wed 7/1511:59 am
RSW
- DSM
2 stops10h 23m
United Airlines
Deal found 6/8![United Airlines logo]()
$454
Last-minute flights from Des Moines to Fort MyersDiscover last-minute flight deals from Des Moines to Fort Myers. Data last updated June 12, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Fort Myers. Data last updated June 12, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/266:30 am
DSM
- RSW
1 stop5h 54m
American Airlines
Tue 7/76:15 am
RSW
- DSM
1 stop7h 50m
American Airlines
Deal found 6/12![American Airlines logo]()
$420
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/26:02 am
DSM
- RSW
2 stops8h 07m
American Airlines
Wed 7/812:47 pm
RSW
- DSM
1 stop8h 31m
American Airlines
Deal found 6/10![American Airlines logo]()
$408
This Delta deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/35:00 pm
DSM
- RSW
1 stop7h 01m
Delta
Wed 7/88:03 am
RSW
- DSM
1 stop6h 31m
Delta
Deal found 6/7![Delta logo]()
$393
This Delta deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/35:00 pm
DSM
- RSW
1 stop7h 01m
Delta
Sun 7/55:37 am
RSW
- DSM
1 stop6h 08m
Delta
Deal found 6/7![Delta logo]()
$403
This American Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/39:02 am
DSM
- RSW
2 stops8h 49m
American Airlines
Fri 7/102:36 pm
RSW
- DSM
1 stop8h 28m
American Airlines
Deal found 6/7![American Airlines logo]()
$431
This Delta deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/72:45 pm
DSM
- RSW
1 stop7h 09m
Delta
Sat 7/116:27 pm
RSW
- DSM
1 stop5h 02m
Delta
Deal found 6/9![Delta logo]()
$429
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/83:45 pm
DSM
- RSW
1 stop6h 00m
Southwest
Tue 7/147:10 am
RSW
- DSM
1 stop5h 20m
Southwest
Deal found 6/8![Southwest logo]()
$359
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/88:53 am
DSM
- RSW
2 stops10h 40m
American Airlines
Tue 7/145:24 pm
RSW
- DSM
1 stop7h 37m
American Airlines
Deal found 6/10![American Airlines logo]()
$372
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/204:40 pm
DSM
- RSW
1 stop5h 05m
Southwest
Wed 7/221:05 pm
RSW
- DSM
2 stops10h 45m
Southwest
Deal found 6/8![Southwest logo]()
$398
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/204:40 pm
DSM
- RSW
1 stop5h 05m
Southwest
Sun 7/267:20 am
RSW
- DSM
1 stop5h 05m
Southwest
Deal found 6/8![Southwest logo]()
$427
One-way flights from Des Moines to Fort MyersSearch for one-way flight options from Des Moines to Fort Myers. Find affordable one-way fares based on user searches. Data last updated June 12, 2026.
Search for one-way flight options from Des Moines to Fort Myers. Find affordable one-way fares based on user searches. Data last updated June 12, 2026.
This American Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/168:03 am
DSM
- RSW
1 stop5h 01m
American Airlines
Deal found 6/9![American Airlines logo]()
$138
This Southwest deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/166:10 am
DSM
- RSW
2 stops9h 50m
Southwest
Deal found 6/9![Southwest logo]()
$144
This Kiwi.com deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/34:40 pm
DSM
- RSW
2 stops28h 18m
Multiple Airlines
Deal found 6/10![Multiple Airlines logo]()
$206
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/35:12 am
DSM
- RSW
1 stop7h 19m
American Airlines
Deal found 6/10![American Airlines logo]()
$214
This KAYAK deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/251:33 pm
DSM
- RSW
1 stop8h 24m
American Airlines
Deal found 6/10![American Airlines logo]()
$236
This United Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/156:00 am
DSM
- RSW
1 stop7h 44m
United Airlines
Deal found 6/7![United Airlines logo]()
$259
This United Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/211:34 am
DSM
- RSW
1 stop9h 16m
United Airlines
Deal found 6/11![United Airlines logo]()
$269
This Kiwi.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/256:00 am
DSM
- RSW
2 stops33h 06m
Multiple Airlines
Deal found 6/12![Multiple Airlines logo]()
$299
This Kiwi.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1612:44 pm
DSM
- RSW
3 stops32h 03m
Multiple Airlines
Deal found 6/9![Multiple Airlines logo]()
$304
Find flight deals from Des Moines to Fort Myers
Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Fort Myers (RSW). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 12, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $293 (Southwest) |
One-way from | $138 (American Airlines) |
Popular in | June |
Cheapest in | May |
Average price | $382 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Fort Myers that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2026.
Use the filters below to find and compare flights from Des Moines to Fort Myers that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesFort Myers
DSM - RSW
DSMRSW
Des Moines
Sat 8/15
6:55 am-1:33 pm
1 stop5h 38m
Fort Myers SW Florida Intl
Mon 8/17
11:00 am-5:50 pm
1 stop7h 50m
$333
Quickest round-trip
Des MoinesFort Myers
DSM - RSW
DSMRSW
Des Moines
Thu 7/23
6:37 pm-12:23 am
1 stop4h 46m
Fort Myers SW Florida Intl
Mon 7/27
6:27 pm-10:29 pm
1 stop5h 02m
$427
Des MoinesFort Myers
DSM - RSW
DSMRSW
Des Moines
Fri 6/26
2:45 pm-11:58 pm
1 stop8h 13m
Fort Myers SW Florida Intl
Tue 7/7
6:45 am-1:34 pm
1 stop7h 49m
$433
Des MoinesFort Myers
DSM - RSW
DSMRSW
Des Moines
Wed 8/5
6:00 am-2:44 pm
1 stop7h 44m
Fort Myers SW Florida Intl
Mon 8/10
4:39 pm-10:56 pm
1 stop7h 17m
$441
Des MoinesFort Myers
DSM - RSW
DSMRSW
Des Moines
Sat 8/29
5:45 am-3:27 pm
1 stop8h 42m
Fort Myers SW Florida Intl
Wed 9/2
4:40 pm-9:23 pm
1 stop5h 43m
$444
Des MoinesFort Myers
DSM - RSW
DSMRSW
Des Moines
Thu 10/1
6:00 am-1:01 pm
1 stop6h 01m
Fort Myers SW Florida Intl
Wed 10/7
12:16 pm-9:23 pm
2 stops10h 07m
$449
Des MoinesFort Myers
DSM - RSW
DSMRSW
Des Moines
Mon 8/3
5:10 am-4:30 pm
2 stops10h 20m
Fort Myers SW Florida Intl
Fri 8/7
3:40 pm-10:10 pm
2 stops7h 30m
$453
Des MoinesFort Myers
DSM - RSW
DSMRSW
Des Moines
Tue 7/14
11:23 am-8:34 pm
1 stop8h 11m
Fort Myers SW Florida Intl
Wed 7/15
11:59 am-9:22 pm
2 stops10h 23m
$454
Cheapest one-way
Quickest one-way
Des MoinesFort Myers
DSM - RSW
DSMRSW
Des Moines
Wed 9/16
8:03 am-2:04 pm
1 stop5h 01m
$138
Des MoinesFort Myers
DSM - RSW
DSMRSW
Des Moines
Wed 9/16
6:10 am-5:00 pm
2 stops9h 50m
$144
Showing 1-10 of 19 resultsSorted by cheapest first
Compare providers for flights from Des Moines to Fort Myers
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Fort Myers in June.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Des Moines-Fort Myers flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Fort Myers flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Fort Myers flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Des Moines-Fort Myers flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Fort Myers flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Des Moines to Fort Myers
Have a flexible travel schedule? Discover the best time to fly to Fort Myers from Des Moines with our price prediction graph.
DSM-RSW
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Fort Myers
How far ahead should I book a flight from Des Moines to Fort Myers?
The price you pay for your flight from Des Moines to Fort Myers may vary depending on when you book. For the best chance of a lower fare, look to book 18 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Des Moines to Fort Myers?
Currently, May is the cheapest month in which you can book a flight from Des Moines to Fort Myers (average of $214). Flying from Des Moines to Fort Myers in June is currently the most expensive (average of $382). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Des Moines to Fort Myers?
Reviews of airlines servicing Fort Myers
Get insights into the airlines that provide service to Fort Myers. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Fort Myers. Reviews last updated June 12, 2026.
Read reviews from past customers who have flown Southwest,Delta, andUnited Airlines from Des Moines to Fort Myers. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.6
Overall
7.9
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Food
7.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Crew
8.6
Overall
7.9
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Food
7.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Crew
8.6
Overall
7.9
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Food
7.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Crew
8.6
Overall
7.9
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Food
7.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Crew
8.6
Overall
7.9
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Food
7.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Crew
8.6
Overall
7.9
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Food
7.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Fort Myers. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Des Moines and Fort Myers flights
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Top 5 airlines flying from Des Moines to Fort Myers
Discover the top 5 airlines that operate flights from Des Moines to Fort Myers. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$92 | Average$222 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$203 | Average$404 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$260 | Average$360 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$263 | Average$387 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$299 | Average$403 | FlexibilityNo cancel fee | On-time63% |