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$135+ Cheap flights from Des Moines to Fort Myers (DSM - RSW)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/4. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — RSW
Jun 17 — Jun 241
Wed 6/17
Wed 6/24
1 adult, Economy
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Find cheap flights from Des Moines to Fort Myers with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

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Cheapflights Tip: The best prices from Des Moines to Fort Myers SW Florida Intl are usually found in April or January, booked 19 days in advance, depart on a Monday or Tuesday and return on a Monday

Cheap flight deals from Des Moines to Fort Myers

Cheapest flights from Des Moines to Fort Myers
Explore the most affordable flight options available from Des Moines to Fort Myers. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 18, 2026.

This Kiwi.com deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/43:04 pm
DSM
-
RSW
Nonstop2h 59m
Allegiant Air
Mon 9/77:40 pm
RSW
-
DSM
Nonstop3h 15m
Allegiant Air
Deal found 5/15$135
This Kiwi.com deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/63:11 pm
DSM
-
RSW
Nonstop2h 59m
Allegiant Air
Mon 11/97:30 pm
RSW
-
DSM
Nonstop3h 15m
Allegiant Air
Deal found 5/16$182
This Kiwi.com deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/42:16 pm
DSM
-
RSW
2 stops30h 41m
Multiple Airlines
Mon 9/77:40 pm
RSW
-
DSM
Nonstop3h 15m
Multiple Airlines
Deal found 5/15$311
This American Airlines deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/306:30 am
DSM
-
RSW
1 stop5h 54m
American Airlines
Tue 7/76:15 am
RSW
-
DSM
1 stop7h 50m
American Airlines
Deal found 5/16$336
This Delta deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/252:45 pm
DSM
-
RSW
1 stop8h 13m
Delta
Mon 7/65:37 am
RSW
-
DSM
1 stop6h 06m
Delta
Deal found 5/17$339
This American Airlines deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/96:00 am
DSM
-
RSW
1 stop9h 08m
American Airlines
Sat 9/125:44 pm
RSW
-
DSM
2 stops6h 44m
American Airlines
Deal found 5/16$344
This Delta deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/92:25 pm
DSM
-
RSW
1 stop5h 47m
Delta
Tue 6/165:37 am
RSW
-
DSM
1 stop6h 06m
Delta
Deal found 5/14$349
This American Airlines deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/95:30 am
DSM
-
RSW
2 stops8h 36m
American Airlines
Tue 6/166:24 pm
RSW
-
DSM
1 stop6h 26m
American Airlines
Deal found 5/16$354
This American Airlines deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/176:00 am
DSM
-
RSW
1 stop9h 08m
American Airlines
Mon 9/215:44 pm
RSW
-
DSM
2 stops6h 44m
American Airlines
Deal found 5/17$359
This American Airlines deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/201:41 pm
DSM
-
RSW
1 stop8h 12m
American Airlines
Thu 7/305:24 pm
RSW
-
DSM
1 stop7h 37m
American Airlines
Deal found 5/14$363

Find flight deals from Des Moines to Fort Myers

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Fort Myers (RSW). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 18, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$135
(Kiwi.com)

Popular in

June

Cheapest in

April

Average price

$343
Provider with most accurate pricing for Des Moines-Fort Myers SW Florida Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Fort Myers SW Florida Intl flights.
Search Deals
From Des Moines to Fort Myers SW Florida Intl
Search Deals
Highest demand for flights based on searches. 17% potential increase in price ($68 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($11 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in May 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Fort Myers that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 18, 2026.
Use the filters below to find and compare flights from Des Moines to Fort Myers that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Tue 6/9

2:25 pm-9:12 pm

1 stop5h 47m

Fort Myers SW Florida Intl

Tue 6/16

5:37 am-10:43 am

1 stop6h 06m

$349

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Fri 7/10

6:00 am-2:44 pm

1 stop7h 44m

Fort Myers SW Florida Intl

Tue 7/14

5:00 pm-10:35 pm

1 stop6h 35m

$383
Quickest round-trip

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Thu 9/17

7:00 am-1:18 pm

1 stop5h 18m

Fort Myers SW Florida Intl

Sun 9/20

5:35 am-10:14 am

1 stop5h 39m

$383

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Thu 8/6

6:55 am-1:59 pm

1 stop6h 04m

Fort Myers SW Florida Intl

Sun 8/9

6:40 am-10:34 am

1 stop4h 54m

$383

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Fri 5/29

4:20 pm-10:40 pm

1 stop5h 20m

Fort Myers SW Florida Intl

Mon 6/1

7:35 am-1:10 pm

1 stop6h 35m

$423

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Wed 7/22

5:20 am-4:40 pm

2 stops10h 20m

Fort Myers SW Florida Intl

Fri 7/31

2:05 pm-11:30 pm

2 stops10h 25m

$473

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Fri 7/3

6:10 am-6:40 pm

2 stops11h 30m

Fort Myers SW Florida Intl

Mon 7/6

2:05 pm-11:30 pm

2 stops10h 25m

$477

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Fri 6/19

4:40 pm-10:40 pm

1 stop5h 00m

Fort Myers SW Florida Intl

Mon 6/22

2:05 pm-11:30 pm

2 stops10h 25m

$482

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Tue 6/30

5:20 am-4:40 pm

2 stops10h 20m

Fort Myers SW Florida Intl

Sun 7/5

6:00 am-3:35 pm

2 stops10h 35m

$497

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Sat 5/30

6:40 am-4:15 pm

2 stops8h 35m

Fort Myers SW Florida Intl

Wed 6/3

7:00 am-11:25 am

1 stop5h 25m

$512

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/16

Showing 1-10 of 21 resultsSorted by cheapest first
1
2
3

Compare providers for flights from Des Moines to Fort Myers

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Fort Myers in May.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
PricelinePrice Accuracy1 starTrust Score*3 stars
MytripPrice Accuracy3 starsTrust Score*3 stars
Kiwi.comPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Des Moines-Fort Myers flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Fort Myers flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Fort Myers flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Des Moines-Fort Myers flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Fort Myers flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Fort Myers

Have a flexible travel schedule? Discover the best time to fly to Fort Myers from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Fort Myers

How far ahead should I book a flight from Des Moines to Fort Myers?

The price you pay for your flight from Des Moines to Fort Myers may vary depending on when you book. For the best chance of a lower fare, look to book 18 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Des Moines to Fort Myers?

Currently, April is the cheapest month in which you can book a flight from Des Moines to Fort Myers (average of $225). Flying from Des Moines to Fort Myers in June is currently the most expensive (average of $428). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to RSW?

Find hourly flight availability from Des Moines to Fort Myers. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 18, 2026.

When flying from Des Moines to Fort Myers, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

How much does it cost to fly round-trip from Des Moines to Fort Myers?

Reviews of airlines servicing Fort Myers

Get insights into the airlines that provide service to Fort Myers. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Fort Myers. Reviews last updated May 18, 2026.
Read reviews from past customers who have flown Southwest,Delta, andUnited Airlines from Des Moines to Fort Myers. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
7.9
Good
4,286 reviews

Food

7.0

Comfort

8.0

Crew

8.6

Entertainment

7.5

Boarding

8.1

Overall

7.9

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
Southwest
7.9
Good
4,286 reviews
Southwest
7.9
Good
4,286 reviews

Food

7.0

Comfort

8.0

Crew

8.6

Entertainment

7.5

Boarding

8.1

Overall

7.9

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
Delta
7.9
Good
8,449 reviews
Southwest
7.9
Good
4,286 reviews

Food

7.0

Comfort

8.0

Crew

8.6

Entertainment

7.5

Boarding

8.1

Overall

7.9

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
United Airlines
7.4
Good
9,736 reviews
Southwest
7.9
Good
4,286 reviews

Food

7.0

Comfort

8.0

Crew

8.6

Entertainment

7.5

Boarding

8.1

Overall

7.9

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
Allegiant Air
7.3
Good
709 reviews
Southwest
7.9
Good
4,286 reviews

Food

7.0

Comfort

8.0

Crew

8.6

Entertainment

7.5

Boarding

8.1

Overall

7.9

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
American Airlines
7.1
Good
11,648 reviews
Southwest
7.9
Good
4,286 reviews

Food

7.0

Comfort

8.0

Crew

8.6

Entertainment

7.5

Boarding

8.1

Overall

7.9

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Fort Myers. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Des Moines to Fort Myers flight route?

    Within the past month, 1 users have taken a look at flights from Des Moines to Fort Myers SW Florida Intl.

  • How long is the flight from Des Moines to Fort Myers?

    A quick flight from Des Moines to Fort Myers can take about 5h 20m. Delta provides one of the quickest options available for as low as $423. The distance from Des Moines to Fort Myers is about 1237 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Des Moines to Fort Myers round-trip?

    Cheapflights users have booked flights from Des Moines to Fort Myers round-trip from $92. Other airlines that can offer you cheap pricing are Delta, from $203, and United Airlines, from $260. Allegiant Air is currently priced 70% below the average price you’ll pay for this route.

  • What are the cheapest airlines to fly from Des Moines to Fort Myers one-way?

    One-way options have recently been found by users for as low as $54 on Allegiant Air. Other airlines that offer cheap prices include United Airlines from $114 and American Airlines from $125 one-way.

  • What are the cheapest flights from Des Moines to Fort Myers?

    The cheapest flight price from Des Moines to Fort Myers is $65. On average you can expect to pay $135. The most popular route, (Des Moines - Fort Myers SW Florida Intl), can usually be booked for $135.

  • Can I find deals for flights from Des Moines to Fort Myers that include hotel bookings?

    Yes. In addition to deals on Des Moines to Fort Myers flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Fort Myers?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Fort Myers.

  • Can I find deals for business class flights from Des Moines to Fort Myers?

    Yes. Cheapflights offers flight deals from Des Moines to Fort Myers by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Fort Myers?

    Currently, April is the cheapest month in which you can book a flight from Des Moines to Fort Myers (average of $225). Flying from Des Moines to Fort Myers in June is currently the most expensive (average of $428). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Fort Myers?

Book flights to Fort Myers if you plan to visit one of these locations
North Fort Myers
Estero
Sanibel

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Top 5 airlines flying from Des Moines to Fort Myers

Discover the top 5 airlines that operate flights from Des Moines to Fort Myers. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 18, 2026.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$92Average$222FlexibilityNo cancel feeOn-time88%
DeltaCheapest$203Average$404FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$260Average$360FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$263Average$398FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$299Average$403FlexibilityNo cancel feeOn-time63%

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