What are the cheapest airlines flying from Des Moines to Fort Myers round-trip?

Cheapflights users have booked flights from Des Moines to Fort Myers round-trip from $317. Other airlines that can offer you cheap pricing are American Airlines, from $322, and United Airlines, from $397. Delta is currently priced 21% below the average price you’ll pay for this route.

What is the cheapest day to fly from Des Moines to Fort Myers?

Travelers seeking maximum savings on their Des Moines to Fort Myers flight should consider departing on Tuesday at noon when fares are most often at their lowest. Sunday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

In terms of precipitation, rainfall in Fort Myers ranges from 1.7 - 10.1 inches per month. June is typically the wettest month, when rainfall can reach 10.1 in. December is typically the driest time to visit Fort Myers when rainfall is around 1.7 in.

If weather is an important factor for your trip to Fort Myers, use this chart to help with planning. For those seeking warmer temperatures, August is the ideal time of year to visit, when temperatures reach an average of 84.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 64.4 F).

What are the most popular airlines that fly from Des Moines to Fort Myers?

When booking a flight from Des Moines to Fort Myers, you may want to consider flying on American Airlines, Delta or Allegiant Air as they are the most popular for this route.

What is the cheapest day to fly round-trip from Des Moines to Fort Myers?

Flying to your destination on a Saturday can be more expensive, but this shouldn’t discourage you from finding affordable options to get to Fort Myers. Check prices with Cheapflights to find a great deal for your trip.

How far in advance should I book a flight from Des Moines to Fort Myers?

Users have found that booking a flight from Des Moines to Fort Myers at least 10 days early can save you up to 5% on average compared to booking a flight this week. If booking 10 days before your flight isn’t an option for you, users have found flights from Des Moines to Fort Myers for as little as $296 when booking for a departure date within the next two weeks. You can also check prices now. Some users have found airline tickets as low as $812 for flights departing within the next 3 days.

What is the cheapest month to fly from Des Moines to Fort Myers?

August can be a great time to fly to Fort Myers from Des Moines with a flight ticket averaging about $402. Cheapflights users have found deals in the month of August for as cheap as $276. The most expensive prices can be found in the month of March.

Can I find deals for flights from Des Moines to Fort Myers that include hotel bookings?

Yes. In addition to deals on Des Moines to Fort Myers flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Des Moines to Fort Myers?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Fort Myers.

Can I find deals for business class flights from Des Moines to Fort Myers?

Yes. Cheapflights offers flight deals from Des Moines to Fort Myers by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$193+ Flights from Des Moines to Fort Myers

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1. Tell us where you want to go

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Cheapflights Tip: The best prices from Des Moines to Fort Myers SW Florida Intl are usually found in August or September, booked 87 days in advance, depart on a Tuesday or Wednesday and return on a Friday

Cheap flight deals from Des Moines to Fort Myers

Round-trip from	$317 (Delta)
One-way from	$193 (Mytrip)
Popular in	March
Cheapest in	August
Average price	$416

From Des Moines to Fort Myers SW Florida Intl

Search Deals

One-way flight from Des Moines to Fort Myers SW Florida Intl

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Highest demand for flights based on searches. 15% potential increase in price ($74 potential increase over avg. RT price).

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Cheapest flight prices on average. 3% potential price decrease ($13 potential savings vs. average RT price).

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Average for round-trip flights in July 2025

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Find flight deals from Des Moines to Fort Myers

Cheapest flights from Des Moines to Fort Myers
Explore the most affordable flight options available from Des Moines to Fort Myers. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 1, 2025.

Sat 8/23:00 pmDSM - RSW

1 stop7h 02mDelta

Mon 8/117:00 amRSW - DSM

1 stop4h 38mDelta

Deal found 6/30

$317

Wed 7/305:00 amDSM - RSW

2 stops9h 17mAmerican Airlines

Tue 8/54:26 pmRSW - DSM

1 stop8h 18mAmerican Airlines

Deal found 6/30

$322

Sat 7/261:13 pmDSM - RSW

2 stops20h 05mMultiple Airlines

Thu 7/317:20 pmRSW - DSM

2 stops23h 45mMultiple Airlines

Deal found 6/30

$326

Tue 8/56:24 amDSM - RSW

1 stop7h 38mUnited Airlines

Thu 8/75:30 pmRSW - DSM

1 stop5h 47mUnited Airlines

Deal found 6/30

$397

Sun 11/306:50 pmDSM - RSW

1 stop4h 30mSouthwest

Mon 12/812:30 pmRSW - DSM

1 stop8h 25mSouthwest

Deal found 6/30

$416

Best flights from Des Moines to Fort Myers
Discover carefully curated flight deals from Des Moines to Fort Myers that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 1, 2025.

Sat 8/23:00 pmDSM - RSW

1 stop7h 02mDelta

Mon 8/117:00 amRSW - DSM

1 stop4h 38mDelta

Deal found 6/30

$317

Wed 7/305:00 amDSM - RSW

2 stops9h 17mAmerican Airlines

Tue 8/54:26 pmRSW - DSM

1 stop8h 18mAmerican Airlines

Deal found 6/30

$322

Sat 7/261:13 pmDSM - RSW

2 stops20h 05mMultiple Airlines

Thu 7/317:20 pmRSW - DSM

2 stops23h 45mMultiple Airlines

Deal found 6/30

$326

Tue 8/56:24 amDSM - RSW

1 stop7h 38mUnited Airlines

Thu 8/75:30 pmRSW - DSM

1 stop5h 47mUnited Airlines

Deal found 6/30

$397

Last-minute flights from Des Moines to Fort Myers
Discover last-minute flight deals from Des Moines to Fort Myers. Data last updated July 1, 2025 and is based on user searches.

Thu 7/106:02 amDSM - RSW

1 stop14h 58mUnited Airlines

Tue 7/154:36 pmRSW - DSM

1 stop7h 24mUnited Airlines

Deal found 7/1

$612

Sat 7/261:13 pmDSM - RSW

2 stops20h 05mMultiple Airlines

Thu 7/317:20 pmRSW - DSM

2 stops23h 45mMultiple Airlines

Deal found 6/30

$326

Wed 7/305:00 amDSM - RSW

2 stops9h 17mAmerican Airlines

Tue 8/54:26 pmRSW - DSM

1 stop8h 18mAmerican Airlines

Deal found 6/30

$322

Sat 8/23:00 pmDSM - RSW

1 stop7h 02mDelta

Mon 8/117:00 amRSW - DSM

1 stop4h 38mDelta

Deal found 6/30

$317

Tue 8/56:24 amDSM - RSW

1 stop7h 38mUnited Airlines

Thu 8/75:30 pmRSW - DSM

1 stop5h 47mUnited Airlines

Deal found 6/30

$397

One-way flights from Des Moines to Fort Myers
Search for one-way flight options from Des Moines to Fort Myers. Find affordable one-way fares based on user searches. Data last updated July 1, 2025.

Mon 7/141:15 pmDSM - RSW

2 stops30h 14mMultiple Airlines

Deal found 6/29

$193

Mon 7/145:00 amDSM - RSW

1 stop5h 43mAmerican Airlines

Deal found 6/29

$224

Cheapflights Fare Finder

Use the filters below to find and compare flights from Des Moines to Fort Myers that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Sat 8/2

3:00 pm-11:02 pm

1 stop7h 02m

Fort Myers SW Florida Intl

Mon 8/11

7:00 am-10:38 am

1 stop4h 38m

$317

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Wed 7/30

5:00 am-3:17 pm

2 stops9h 17m

Fort Myers SW Florida Intl

Tue 8/5

4:26 pm-11:44 pm

1 stop8h 18m

$322

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Sat 7/26

1:13 pm-10:18 am

2 stops20h 05m

Fort Myers SW Florida Intl

Thu 7/31

7:20 pm-6:05 pm

2 stops23h 45m

$326

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Tue 8/5

6:24 am-3:02 pm

1 stop7h 38m

Fort Myers SW Florida Intl

Thu 8/7

5:30 pm-10:17 pm

1 stop5h 47m

$397

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Mon 7/14

1:15 pm-8:29 pm

2 stops30h 14m

$193

Des MoinesFort Myers

DSM - RSW

DSMRSW

Des Moines

Mon 7/14

5:00 am-11:43 am

1 stop5h 43m

$224

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/29

Best time to book a flight from Des Moines to Fort Myers

Have a flexible travel schedule? Discover the best time to fly to Fort Myers from Des Moines with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Fort Myers

How far ahead should I book a flight from Des Moines to Fort Myers?

The price you pay for your flight from Des Moines to Fort Myers may vary depending on when you book. For the best chance of a lower fare, look to book 87 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Des Moines to Fort Myers?

Currently, January is the cheapest month in which you can book a flight from Des Moines to Fort Myers (average of $205). Flying from Des Moines to Fort Myers in June is currently the most expensive (average of $294). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to RSW?

A simple way to save on the total cost of your ticket is to fly from Des Moines to Fort Myers at noon. If you’re flexible enough to do this you can expect to save up to 19% on your trip compared to booking a flight in the morning.

Reviews of airlines servicing Fort Myers

Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from Des Moines to Fort Myers. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,973 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Delta

8.0

Very good

7,973 reviews

Delta

8.0

Very good

7,973 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

United Airlines

7.4

Good

8,858 reviews

Delta

8.0

Very good

7,973 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

7,973 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

What are the cheapest airlines flying from Des Moines to Fort Myers round-trip?
Cheapflights users have booked flights from Des Moines to Fort Myers round-trip from $317. Other airlines that can offer you cheap pricing are American Airlines, from $322, and United Airlines, from $397. Delta is currently priced 21% below the average price you’ll pay for this route.
Can I find deals for flights from Des Moines to Fort Myers that include hotel bookings?
Yes. In addition to deals on Des Moines to Fort Myers flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Des Moines to Fort Myers?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Fort Myers.
Can I find deals for business class flights from Des Moines to Fort Myers?
Yes. Cheapflights offers flight deals from Des Moines to Fort Myers by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Des Moines to Fort Myers?
Currently, January is the cheapest month in which you can book a flight from Des Moines to Fort Myers (average of $205). Flying from Des Moines to Fort Myers in June is currently the most expensive (average of $294). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Sanibel

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Complete your trip

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Top 5 airlines flying from Des Moines to Fort Myers

Airline	Cheapest	Average	Flexibility	On-time
Allegiant Air	Cheapest$107	Average$296	FlexibilityNo cancel fee	On-time88%
United Airlines	Cheapest$276	Average$462	FlexibilityNo cancel fee	On-time69%
Delta	Cheapest$284	Average$400	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$306	Average$389	FlexibilityNo cancel fee	On-time71%
Southwest	Cheapest$316	Average$456	FlexibilityNo cancel fee	On-time63%

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$193+ Cheap flights from Des Moines to Fort Myers (DSM - RSW)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/14. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Des Moines to Fort Myers with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheapflights Tip: The best prices from Des Moines to Fort Myers SW Florida Intl are usually found in August or September, booked 87 days in advance, depart on a Tuesday or Wednesday and return on a Friday

Cheap flight deals from Des Moines to Fort Myers

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Des Moines to Fort Myers

Cheapest flights from Des Moines to Fort MyersExplore the most affordable flight options available from Des Moines to Fort Myers. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 1, 2025.

Explore the most affordable flight options available from Des Moines to Fort Myers. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 1, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Des Moines to Fort Myers that are best for you.

Best time to book a flight from Des Moines to Fort Myers

Have a flexible travel schedule? Discover the best time to fly to Fort Myers from Des Moines with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Fort Myers

How far ahead should I book a flight from Des Moines to Fort Myers?

Use this chart to determine the optimal time to book a round-trip flight from Des Moines to Fort Myers. Price data was last updated on June 27, 2025.

What is the cheapest month to book a flight from Des Moines to Fort Myers?

What is the cheapest time of day to fly from DSM to RSW?

Find hourly flight availability from Des Moines to Fort Myers. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 1, 2025.

Reviews of airlines servicing Fort Myers

Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from Des Moines to Fort Myers. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Fort Myers. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What are the cheapest airlines flying from Des Moines to Fort Myers round-trip?

Can I find deals for flights from Des Moines to Fort Myers that include hotel bookings?

How can I find direct flights from Des Moines to Fort Myers?

Can I find deals for business class flights from Des Moines to Fort Myers?

What is the cheapest month to book a flight from Des Moines to Fort Myers?

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Alternative routes for Des Moines to Fort Myers

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Top 5 airlines flying from Des Moines to Fort Myers

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Cheapest flights from Des Moines to Fort Myers
Explore the most affordable flight options available from Des Moines to Fort Myers. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 1, 2025.