$94+ Cheap flights from Tampa to Des Moines (TPA - DSM)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/10. Fares are subject to change and may not be available on all flights or dates of travel.
TPA — DSM
Dec 6 — Dec 131
Round-trip
1 adult, Economy
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Find cheap flights from Tampa to Des Moines with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Tampa to Des Moines
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Cheapest flights from Tampa to Des MoinesExplore the most affordable flight options available from Tampa to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 6, 2026.
Explore the most affordable flight options available from Tampa to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 6, 2026.
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/17:20 am -
1 stop7h 53m
Tue 12/85:20 am -
1 stop5h 55m
Deal found 11/3![Delta logo]()
$237
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/15:30 pm -
1 stop5h 51m
Tue 12/86:15 am -
2 stops8h 47m
Deal found 11/3![United Airlines logo]()
$242
This CheapOair deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/106:00 am -
1 stop14h 42m
Sun 12/138:39 pm -
1 stop25h 58m
Deal found 11/5![Frontier logo]()
$244
This Southwest deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/166:05 pm -
1 stop5h 00m
Wed 12/235:40 pm -
1 stop6h 15m
Deal found 11/1![Southwest logo]()
$330
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/106:35 pm -
1 stop5h 40m
Sun 12/136:15 am -
2 stops7h 55m
Deal found 11/5![United Airlines logo]()
$335
This CheapOair deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/136:15 am -
1 stop14h 20m
Mon 11/168:30 pm -
1 stop26h 57m
Deal found 11/1![Frontier logo]()
$350
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/254:20 pm -
1 stop7h 15m
Sat 11/286:13 am -
1 stop5h 59m
Deal found 11/3![Delta logo]()
$357
This Trip.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/96:15 am -
1 stop14h 20m
Mon 11/168:30 pm -
1 stop26h 57m
Deal found 11/1![Frontier logo]()
$362
This Southwest deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/13:00 pm -
2 stops8h 05m
Tue 12/86:00 am -
2 stops6h 10m
Deal found 11/3![Southwest logo]()
$395
This Delta deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/204:20 pm -
1 stop7h 15m
Mon 11/235:30 am -
1 stop5h 45m
Deal found 11/2![Delta logo]()
$400
Best flights from Tampa to Des MoinesDiscover carefully curated flight deals from Tampa to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 6, 2026.
Discover carefully curated flight deals from Tampa to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 6, 2026.
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/72:00 pm -
2 stops8h 25m
Wed 12/92:56 pm -
1 stop6h 00m
Deal found 11/5![United Airlines logo]()
$242
This Southwest deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/166:05 pm -
1 stop5h 00m
Wed 12/235:40 pm -
1 stop6h 15m
Deal found 11/1![Southwest logo]()
$330
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/254:20 pm -
1 stop7h 15m
Sat 11/286:13 am -
1 stop5h 59m
Deal found 11/3![Delta logo]()
$357
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/106:35 pm -
1 stop5h 40m
Sun 12/136:15 am -
2 stops7h 55m
Deal found 11/5![United Airlines logo]()
$335
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/219:55 am -
1 stop7h 16m
Mon 1/253:00 pm -
1 stop5h 46m
Deal found 11/5![United Airlines logo]()
$347
Last-minute flights from Tampa to Des MoinesDiscover last-minute flight deals from Tampa to Des Moines. Data last updated November 6, 2026 and is based on user searches.
Discover last-minute flight deals from Tampa to Des Moines. Data last updated November 6, 2026 and is based on user searches.
This Trip.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/96:15 am -
1 stop14h 20m
Mon 11/168:30 pm -
1 stop26h 57m
Deal found 11/1![Frontier logo]()
$362
This CheapOair deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/136:15 am -
1 stop14h 20m
Mon 11/168:30 pm -
1 stop26h 57m
Deal found 11/1![Frontier logo]()
$350
This Delta deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/204:20 pm -
1 stop7h 15m
Mon 11/235:30 am -
1 stop5h 45m
Deal found 11/2![Delta logo]()
$400
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/254:20 pm -
1 stop7h 15m
Sat 11/286:13 am -
1 stop5h 59m
Deal found 11/3![Delta logo]()
$357
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/17:20 am -
1 stop7h 53m
Tue 12/85:20 am -
1 stop5h 55m
Deal found 11/3![Delta logo]()
$237
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/15:30 pm -
1 stop5h 51m
Tue 12/86:15 am -
2 stops8h 47m
Deal found 11/3![United Airlines logo]()
$242
This Southwest deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/13:00 pm -
2 stops8h 05m
Tue 12/86:00 am -
2 stops6h 10m
Deal found 11/3![Southwest logo]()
$395
This CheapOair deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/106:00 am -
1 stop14h 42m
Sun 12/138:39 pm -
1 stop25h 58m
Deal found 11/5![Frontier logo]()
$244
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/106:35 pm -
1 stop5h 40m
Sun 12/136:15 am -
2 stops7h 55m
Deal found 11/5![United Airlines logo]()
$335
This Southwest deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/166:05 pm -
1 stop5h 00m
Wed 12/235:40 pm -
1 stop6h 15m
Deal found 11/1![Southwest logo]()
$330
One-way flights from Tampa to Des MoinesSearch for one-way flight options from Tampa to Des Moines. Find affordable one-way fares based on user searches. Data last updated November 6, 2026.
Search for one-way flight options from Tampa to Des Moines. Find affordable one-way fares based on user searches. Data last updated November 6, 2026.
This Super.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/106:00 am -
1 stop14h 42m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![Frontier logo]()
$94
This CheapOair deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/135:38 pm -
1 stop26h 53m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![Frontier logo]()
$100
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/134:15 pm -
2 stops22h 04m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![Multiple Airlines logo]()
$105
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/25:08 pm -
1 stop7h 22m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![American Airlines logo]()
$119
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/22:00 pm -
2 stops8h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![United Airlines logo]()
$124
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/1411:27 am -
2 stops28h 07m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![Multiple Airlines logo]()
$127
This Travelocity deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/136:00 am -
1 stop14h 42m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![Frontier logo]()
$151
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/2311:11 pm -
1 stop23h 42m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![Multiple Airlines logo]()
$160
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/27:52 pm -
3 stops38h 58m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![Multiple Airlines logo]()
$167
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/145:30 pm -
1 stop5h 51m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![United Airlines logo]()
$174
This CheapOair deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/226:30 am -
1 stop14h 03m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![Frontier logo]()
$176
Find flight deals from Tampa to Des Moines
Discover tips and strategies to find the most affordable flight options for your journey from Tampa (TPA) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 6, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $237 (Delta) |
One-way from | $94 (Super.com) |
Popular in | April |
Cheapest in | November |
Average price | $424 |
Good one-way deal | $224 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Tampa to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 6, 2026.
Use the filters below to find and compare flights from Tampa to Des Moines that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
TampaDes Moines
TPA Tampa - DSM Des Moines
TPADSM
Tampa
Thu 1/14
6:15 am-7:31 pm
1 stop14h 16m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$100
TampaDes Moines
TPA Tampa - DSM Des Moines
TPADSM
Tampa
Wed 1/13
5:38 pm-7:31 pm
1 stop26h 53m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$100
TampaDes Moines
TPA Tampa - DSM Des Moines
TPADSM
Tampa
Wed 1/13
10:20 am-4:38 pm
1 stop7h 18m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$119
Quickest round-trip
TampaDes Moines
TPA Tampa - DSM Des Moines
TPADSM
Tampa
Thu 12/17
2:20 pm-6:06 pm
1 stop4h 46m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$119
TampaDes Moines
TPA Tampa - DSM Des Moines
TPADSM
Tampa
Thu 12/10
11:20 am-8:50 pm
2 stops10h 30m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$124
TampaDes Moines
TPA Tampa - DSM Des Moines
TPADSM
Tampa
Wed 12/2
2:00 pm-9:25 pm
2 stops8h 25m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$124
TampaDes Moines
TPA Tampa - DSM Des Moines
TPADSM
Tampa
Wed 12/2
7:52 pm-9:50 am
3 stops38h 58m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$167
TampaDes Moines
TPA Tampa - DSM Des Moines
TPADSM
Tampa
Mon 12/14
5:30 pm-10:21 pm
1 stop5h 51m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$174
TampaDes Moines
TPA Tampa - DSM Des Moines
TPADSM
Tampa
Fri 1/8
2:18 pm-8:22 pm
1 stop7h 04m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$174
TampaDes Moines
TPA Tampa - DSM Des Moines
TPADSM
Tampa
Wed 1/13
7:00 am-8:38 pm
2 stops14h 38m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$179
Showing 1-10 of 16 resultsSorted by cheapest first
Compare providers for flights from Tampa to Des Moines
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Tampa to Des Moines in November.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star |
- Most accurate provider: When it comes to deals on Tampa-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Tampa-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Tampa-Des Moines flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Tampa-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Tampa-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Tampa to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from Tampa with our price prediction graph.
TPA-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Tampa to Des Moines
Reviews of airlines servicing Des Moines
Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated November 6, 2026.
Read reviews from past customers who have flown Delta,United Airlines, andAmerican Airlines from Tampa to Des Moines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Food
7.2
Overall
7.8
Entertainment
7.8
Comfort
7.8
Crew
8.5
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Boarding
8.1
Food
7.2
Overall
7.8
Entertainment
7.8
Comfort
7.8
Crew
8.5
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Boarding
8.1
Food
7.2
Overall
7.8
Entertainment
7.8
Comfort
7.8
Crew
8.5
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Boarding
8.1
Food
7.2
Overall
7.8
Entertainment
7.8
Comfort
7.8
Crew
8.5
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Related info for your journey
Find useful and relevant information for your journey from Tampa to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsAltoona
Clive
West Des Moines
Ames
Johnston
Boone
Norwalk
Ankeny
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Complete your trip
Complete your trip to Des Moines by adding a car rental and/or hotel reservation to your travel itinerary.
Other flights to Des Moines
Explore flights to Des Moines departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on November 6, 2026.
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Find flights from Tampa to Des Moines, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Tampa and Des Moines flights
Browse other Tampa and Des Moines flight options. Last updated on November 6, 2026.
Other flights from Tampa
Browse through other flights departing from Tampa. Flights are based on user searches made on Cheapflights and were last updated on November 6, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from Tampa to Des Moines
Discover the top 3 airlines that operate flights from Tampa to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 6, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$236 | Average$426 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$237 | Average$462 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$635 | Average$906 | FlexibilityNo cancel fee | On-time69% |