$294+ Cheap flights from Tallahassee to Des Moines (TLH - DSM)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/4. Fares are subject to change and may not be available on all flights or dates of travel.
TLH — DSM
Oct 2 — Oct 91
Round-trip
1 adult, Economy
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Find cheap flights from Tallahassee to Des Moines with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Tallahassee to Des Moines
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Best
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One-way
Cheapest flights from Tallahassee to Des MoinesExplore the most affordable flight options available from Tallahassee to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 2, 2026.
Explore the most affordable flight options available from Tallahassee to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 2, 2026.
This American Airlines deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/307:33 pm -
1 stop5h 25m
Wed 12/28:07 am -
1 stop5h 18m
Deal found 8/30![American Airlines logo]()
$445
This Delta deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/308:15 am -
1 stop6h 54m
Wed 12/210:30 am -
2 stops11h 35m
Deal found 8/30![Delta logo]()
$450
This Delta deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/246:10 am -
1 stop5h 36m
Mon 9/282:34 pm -
1 stop4h 34m
Deal found 9/1![Delta logo]()
$497
This Delta deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/165:53 pm -
1 stop5h 33m
Sun 9/205:45 am -
1 stop4h 25m
Deal found 9/1![Delta logo]()
$567
This Delta deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/37:01 pm -
1 stop4h 36m
Thu 9/1711:31 am -
1 stop6h 23m
Deal found 8/29![Delta logo]()
$582
This American Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/166:37 pm -
1 stop5h 35m
Sun 9/206:00 am -
2 stops7h 52m
Deal found 9/1![American Airlines logo]()
$601
This American Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/246:38 pm -
1 stop5h 34m
Mon 9/286:00 am -
2 stops8h 55m
Deal found 9/1![American Airlines logo]()
$602
Best flights from Tallahassee to Des MoinesDiscover carefully curated flight deals from Tallahassee to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 2, 2026.
Discover carefully curated flight deals from Tallahassee to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 2, 2026.
This Delta deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3012:00 pm -
2 stops9h 40m
Wed 12/210:30 am -
2 stops11h 35m
Deal found 8/30![Delta logo]()
$455
This American Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/166:37 pm -
1 stop5h 35m
Sun 9/206:00 am -
2 stops7h 52m
Deal found 9/1![American Airlines logo]()
$601
This Delta deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/246:10 am -
1 stop5h 36m
Mon 9/282:34 pm -
1 stop4h 34m
Deal found 9/1![Delta logo]()
$497
This American Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/246:38 pm -
1 stop5h 34m
Mon 9/286:00 am -
2 stops8h 55m
Deal found 9/1![American Airlines logo]()
$602
This Delta deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals ”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/165:53 pm -
1 stop5h 33m
Sun 9/205:45 am -
1 stop4h 25m
Deal found 9/1![Delta logo]()
$567
This American Airlines deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/146:48 am -
1 stop7h 55m
Fri 9/186:41 am -
1 stop6h 19m
Deal found 8/30![American Airlines logo]()
$805
This Delta deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/146:10 am -
1 stop5h 36m
Fri 9/186:00 am -
2 stops11h 54m
Deal found 8/30![Delta logo]()
$810
Last-minute flights from Tallahassee to Des MoinesDiscover last-minute flight deals from Tallahassee to Des Moines. Data last updated September 2, 2026 and is based on user searches.
Discover last-minute flight deals from Tallahassee to Des Moines. Data last updated September 2, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/37:01 pm -
1 stop4h 36m
Thu 9/1711:31 am -
1 stop6h 23m
Deal found 8/29![Delta logo]()
$582
This Delta deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/165:53 pm -
1 stop5h 33m
Sun 9/205:45 am -
1 stop4h 25m
Deal found 9/1![Delta logo]()
$567
This American Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/166:37 pm -
1 stop5h 35m
Sun 9/206:00 am -
2 stops7h 52m
Deal found 9/1![American Airlines logo]()
$601
This Delta deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/246:10 am -
1 stop5h 36m
Mon 9/282:34 pm -
1 stop4h 34m
Deal found 9/1![Delta logo]()
$497
This American Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/246:38 pm -
1 stop5h 34m
Mon 9/286:00 am -
2 stops8h 55m
Deal found 9/1![American Airlines logo]()
$602
This American Airlines deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/307:33 pm -
1 stop5h 25m
Wed 12/28:07 am -
1 stop5h 18m
Deal found 8/30![American Airlines logo]()
$445
This Delta deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/308:15 am -
1 stop6h 54m
Wed 12/210:30 am -
2 stops11h 35m
Deal found 8/30![Delta logo]()
$450
One-way flights from Tallahassee to Des MoinesSearch for one-way flight options from Tallahassee to Des Moines. Find affordable one-way fares based on user searches. Data last updated September 2, 2026.
Search for one-way flight options from Tallahassee to Des Moines. Find affordable one-way fares based on user searches. Data last updated September 2, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/48:25 am -
3 stops36h 08m
Deal found 8/30![Multiple Airlines logo]()
$294
This American Airlines deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/46:00 am -
2 stops10h 10m
Deal found 8/30![American Airlines logo]()
$480
Find flight deals from Tallahassee to Des Moines
Discover tips and strategies to find the most affordable flight options for your journey from Tallahassee (TLH) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 2, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $445 (American Airlines) |
One-way from | $294 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from Tallahassee to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 2, 2026.
Use the filters below to find and compare flights from Tallahassee to Des Moines that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
TallahasseeDes Moines
TLH Tallahassee - DSM Des Moines
TLHDSM
Tallahassee
Fri 10/30
12:00 pm-8:40 pm
2 stops9h 40m
Des Moines
Wed 12/2
10:30 am-11:05 pm
2 stops11h 35m
$455
TallahasseeDes Moines
TLH Tallahassee - DSM Des Moines
TLHDSM
Tallahassee
Thu 9/24
6:10 am-10:46 am
1 stop5h 36m
Des Moines
Mon 9/28
2:34 pm-8:08 pm
1 stop4h 34m
$497
Quickest round-trip
TallahasseeDes Moines
TLH Tallahassee - DSM Des Moines
TLHDSM
Tallahassee
Wed 9/16
5:53 pm-10:26 pm
1 stop5h 33m
Des Moines
Sun 9/20
5:45 am-11:10 am
1 stop4h 25m
$567
TallahasseeDes Moines
TLH Tallahassee - DSM Des Moines
TLHDSM
Tallahassee
Wed 9/16
6:37 pm-11:12 pm
1 stop5h 35m
Des Moines
Sun 9/20
6:00 am-2:52 pm
2 stops7h 52m
$601
TallahasseeDes Moines
TLH Tallahassee - DSM Des Moines
TLHDSM
Tallahassee
Thu 9/24
6:38 pm-11:12 pm
1 stop5h 34m
Des Moines
Mon 9/28
6:00 am-3:55 pm
2 stops8h 55m
$602
TallahasseeDes Moines
TLH Tallahassee - DSM Des Moines
TLHDSM
Tallahassee
Mon 9/14
6:48 am-1:43 pm
1 stop7h 55m
Des Moines
Fri 9/18
6:41 am-2:00 pm
1 stop6h 19m
$805
TallahasseeDes Moines
TLH Tallahassee - DSM Des Moines
TLHDSM
Tallahassee
Mon 9/14
6:10 am-10:46 am
1 stop5h 36m
Des Moines
Fri 9/18
6:00 am-6:54 pm
2 stops11h 54m
$810
Cheapest one-way
TallahasseeDes Moines
TLH Tallahassee - DSM Des Moines
TLHDSM
Tallahassee
Sun 10/4
8:25 am-7:33 pm
3 stops36h 08m
$294
Quickest one-way
TallahasseeDes Moines
TLH Tallahassee - DSM Des Moines
TLHDSM
Tallahassee
Sun 10/4
6:00 am-3:10 pm
2 stops10h 10m
$480
Sorted by cheapest first
Compare providers for flights from Tallahassee to Des Moines
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Tallahassee to Des Moines in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Tallahassee-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Tallahassee-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Tallahassee-Des Moines flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Tallahassee-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Tallahassee-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Tallahassee to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from Tallahassee with our price prediction graph.
TLH-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Des Moines
Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated September 2, 2026.
Get a feel of what it's like to fly with American Airlines from Tallahassee to Des Moines by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
7.5
Food
6.4
Overall
7.1
Comfort
7.2
Entertainment
6.8
Crew
7.9
Reviews
1 / 20
8.0
ExcellentOlwin,Jul 2026
MCO - DCA
Boarding
7.5
Food
6.4
Overall
7.1
Comfort
7.2
Entertainment
6.8
Crew
7.9
Reviews
1 / 20
8.0
ExcellentOlwin,Jul 2026
MCO - DCA
Related info for your journey
Find useful and relevant information for your journey from Tallahassee to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsAltoona
Clive
Ames
Johnston
Boone
Norwalk
West Des Moines
Ankeny
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Other flights to Des Moines
Explore flights to Des Moines departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 2, 2026.
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Tallahassee and Des Moines flights
Browse other Tallahassee and Des Moines flight options. Last updated on September 2, 2026.
Other flights from Tallahassee
Browse through other flights departing from Tallahassee. Flights are based on user searches made on Cheapflights and were last updated on September 2, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from Tallahassee to Des Moines
Discover the top airline that operate flights from Tallahassee to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 2, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$336 | Average$491 | FlexibilityNo cancel fee | On-time71% |