$424+ Cheap flights from Des Moines to Tallahassee (DSM - TLH)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/27. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — TLH
Nov 5 — Nov 121
Round-trip
1 adult, Economy
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Find cheap flights from Des Moines to Tallahassee with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Des Moines to Tallahassee
Cheapest
Best
Last-minute
One-way
Cheapest flights from Des Moines to TallahasseeExplore the most affordable flight options available from Des Moines to Tallahassee. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 6, 2026.
Explore the most affordable flight options available from Des Moines to Tallahassee. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 6, 2026.
This American Airlines deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/255:05 am -
1 stop7h 34m
Tue 12/295:29 pm -
1 stop7h 29m
Deal found 10/5![American Airlines logo]()
$465
This Delta deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/283:03 pm -
1 stop7h 01m
Sat 11/712:00 pm -
2 stops9h 40m
Deal found 10/5![Delta logo]()
$470
This American Airlines deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/67:00 am -
1 stop6h 21m
Sat 10/107:33 pm -
1 stop5h 25m
Deal found 10/5![American Airlines logo]()
$497
This Delta deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/63:03 pm -
1 stop7h 01m
Sat 10/108:11 am -
2 stops9h 44m
Deal found 10/5![Delta logo]()
$502
This American Airlines deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/317:02 am -
1 stop7h 01m
Tue 1/59:47 am -
2 stops10h 22m
Deal found 10/6![American Airlines logo]()
$526
Best flights from Des Moines to TallahasseeDiscover carefully curated flight deals from Des Moines to Tallahassee that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 6, 2026.
Discover carefully curated flight deals from Des Moines to Tallahassee that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 6, 2026.
This American Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/317:02 am -
1 stop7h 01m
Tue 1/56:46 pm -
1 stop5h 22m
Deal found 10/4![American Airlines logo]()
$465
This Delta deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/286:00 am -
2 stops7h 39m
Sat 11/712:00 pm -
2 stops9h 40m
Deal found 10/5![Delta logo]()
$475
This Delta deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/203:03 pm -
1 stop7h 01m
Sat 10/246:00 am -
1 stop5h 42m
Deal found 10/5![Delta logo]()
$497
This American Airlines deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/255:05 am -
2 stops8h 58m
Tue 12/297:44 pm -
1 stop5h 14m
Deal found 10/5![American Airlines logo]()
$599
This American Airlines deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/302:26 pm -
1 stop7h 34m
Sun 11/17:45 pm -
1 stop5h 12m
Deal found 10/3![American Airlines logo]()
$631
This American Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/2411:28 am -
1 stop6h 52m
Sun 11/297:35 pm -
1 stop5h 51m
Deal found 10/1![American Airlines logo]()
$681
Last-minute flights from Des Moines to TallahasseeDiscover last-minute flight deals from Des Moines to Tallahassee. Data last updated October 6, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Tallahassee. Data last updated October 6, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/67:00 am -
1 stop6h 21m
Sat 10/107:33 pm -
1 stop5h 25m
Deal found 10/5![American Airlines logo]()
$497
This Delta deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/63:03 pm -
1 stop7h 01m
Sat 10/108:11 am -
2 stops9h 44m
Deal found 10/5![Delta logo]()
$502
This Delta deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/285:35 am -
1 stop4h 39m
Sat 11/712:00 pm -
1 stop4h 16m
Deal found 10/5![Delta logo]()
$465
This American Airlines deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/302:26 pm -
1 stop7h 34m
Sun 11/17:45 pm -
1 stop5h 12m
Deal found 10/3![American Airlines logo]()
$631
This American Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/2411:28 am -
1 stop6h 52m
Sun 11/297:35 pm -
1 stop5h 51m
Deal found 10/1![American Airlines logo]()
$681
This American Airlines deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/253:25 pm -
1 stop7h 12m
Sun 11/295:37 pm -
1 stop7h 49m
Deal found 10/2![American Airlines logo]()
$657
One-way flights from Des Moines to TallahasseeSearch for one-way flight options from Des Moines to Tallahassee. Find affordable one-way fares based on user searches. Data last updated October 6, 2026.
Search for one-way flight options from Des Moines to Tallahassee. Find affordable one-way fares based on user searches. Data last updated October 6, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/278:35 pm -
3 stops40h 47m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/3![Multiple Airlines logo]()
$424
This American Airlines deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/264:11 pm -
1 stop7h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/3![American Airlines logo]()
$520
This American Airlines deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/275:05 am -
1 stop7h 34m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/3![American Airlines logo]()
$591
This Kiwi.com deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/268:35 am -
3 stops26h 57m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/3![Multiple Airlines logo]()
$706
Find flight deals from Des Moines to Tallahassee
Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Tallahassee (TLH). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 6, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $465 (American Airlines) |
One-way from | $424 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Tallahassee that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 6, 2026.
Use the filters below to find and compare flights from Des Moines to Tallahassee that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesTallahassee
DSM Des Moines - TLH Tallahassee
DSMTLH
Des Moines
Sun 12/27
8:35 pm-2:22 pm
3 stops40h 47m
Tallahassee
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$424
Des MoinesTallahassee
DSM Des Moines - TLH Tallahassee
DSMTLH
Des Moines
Thu 12/31
7:02 am-3:03 pm
1 stop7h 01m
Tallahassee
Tue 1/5
6:46 pm-11:08 pm
1 stop5h 22m
$465
Des MoinesTallahassee
DSM Des Moines - TLH Tallahassee
DSMTLH
Des Moines
Wed 10/28
6:00 am-2:39 pm
2 stops7h 39m
Tallahassee
Sat 11/7
12:00 pm-8:40 pm
2 stops9h 40m
$475
Des MoinesTallahassee
DSM Des Moines - TLH Tallahassee
DSMTLH
Des Moines
Tue 10/20
3:03 pm-11:04 pm
1 stop7h 01m
Tallahassee
Sat 10/24
6:00 am-10:42 am
1 stop5h 42m
$497
Quickest round-trip
Des MoinesTallahassee
DSM Des Moines - TLH Tallahassee
DSMTLH
Des Moines
Sat 12/26
4:11 pm-12:41 am
1 stop7h 30m
Tallahassee
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$520
Des MoinesTallahassee
DSM Des Moines - TLH Tallahassee
DSMTLH
Des Moines
Fri 12/25
5:05 am-3:03 pm
2 stops8h 58m
Tallahassee
Tue 12/29
7:44 pm-11:58 pm
1 stop5h 14m
$599
Des MoinesTallahassee
DSM Des Moines - TLH Tallahassee
DSMTLH
Des Moines
Fri 10/30
2:26 pm-11:00 pm
1 stop7h 34m
Tallahassee
Sun 11/1
7:45 pm-11:57 pm
1 stop5h 12m
$631
Des MoinesTallahassee
DSM Des Moines - TLH Tallahassee
DSMTLH
Des Moines
Tue 11/24
11:28 am-7:20 pm
1 stop6h 52m
Tallahassee
Sun 11/29
7:35 pm-12:26 am
1 stop5h 51m
$681
Sorted by cheapest first
Compare providers for flights from Des Moines to Tallahassee
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Tallahassee in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Des Moines-Tallahassee flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Tallahassee flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Tallahassee flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Des Moines-Tallahassee flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Tallahassee flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Des Moines to Tallahassee
Have a flexible travel schedule? Discover the best time to fly to Tallahassee from Des Moines with our price prediction graph.
DSM-TLH
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Tallahassee
Get insights into the airlines that provide service to Tallahassee. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Tallahassee. Reviews last updated October 6, 2026.
Read reviews from past customers who have flown American Airlines from Des Moines to Tallahassee. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
7.9
Overall
7.0
Boarding
7.4
Comfort
7.2
Entertainment
6.8
Food
6.4
Reviews
1 / 20
4.0
OkayElizabeth,Mar 2026
ORD - MIA
Crew
7.9
Overall
7.0
Boarding
7.4
Comfort
7.2
Entertainment
6.8
Food
6.4
Reviews
1 / 20
4.0
OkayElizabeth,Mar 2026
ORD - MIA
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Tallahassee. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Tallahassee?
Book flights to Tallahassee if you plan to visit one of these locationsMidway
Thomasville
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Des Moines and Tallahassee flights
Browse other Des Moines and Tallahassee flight options. Last updated on October 6, 2026.
Other flights from Des Moines
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Top airline flying from Des Moines to Tallahassee
Discover the top airline that operate flights from Des Moines to Tallahassee. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 6, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$420 | Average$493 | FlexibilityNo cancel fee | On-time71% |