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$388+ Cheap flights from Des Moines to Melbourne, FL (DSM - MLB)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/6. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — MLB
May 30 — Jun 61
Sat 5/30
Sat 6/6
1 adult, Economy
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Cheap flight deals from Des Moines to Melbourne

Cheapest flights from Des Moines to Melbourne
Explore the most affordable flight options available from Des Moines to Melbourne. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 30, 2026.

This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1111:04 am
DSM
-
MLB
1 stop5h 58m
Delta
Sat 9/126:35 pm
MLB
-
DSM
1 stop4h 51m
Delta
Deal found 4/30$403
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/127:10 am
DSM
-
MLB
2 stops14h 13m
American Airlines
Wed 8/196:25 am
MLB
-
DSM
1 stop6h 59m
American Airlines
Deal found 4/30$422
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/127:10 am
DSM
-
MLB
2 stops14h 13m
American Airlines
Sat 9/126:24 am
MLB
-
DSM
2 stops9h 49m
American Airlines
Deal found 4/30$427
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/132:15 pm
DSM
-
MLB
1 stop7h 32m
Delta
Tue 8/185:55 am
MLB
-
DSM
1 stop5h 19m
Delta
Deal found 4/30$435
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/296:00 am
DSM
-
MLB
2 stops10h 14m
American Airlines
Sun 9/65:44 pm
MLB
-
DSM
1 stop7h 04m
American Airlines
Deal found 4/30$440
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/205:27 am
DSM
-
MLB
1 stop7h 23m
Delta
Fri 5/295:46 am
MLB
-
DSM
1 stop6h 22m
Delta
Deal found 4/27$449
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/102:15 pm
DSM
-
MLB
1 stop7h 32m
Delta
Tue 8/185:55 am
MLB
-
DSM
1 stop5h 19m
Delta
Deal found 4/30$455
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/205:27 am
DSM
-
MLB
1 stop7h 23m
Delta
Sun 5/246:31 pm
MLB
-
DSM
1 stop5h 01m
Delta
Deal found 4/27$459
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/132:15 pm
DSM
-
MLB
1 stop7h 32m
Delta
Thu 8/205:55 am
MLB
-
DSM
1 stop5h 19m
Delta
Deal found 4/30$467
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/112:15 pm
DSM
-
MLB
1 stop7h 32m
Delta
Fri 9/186:35 pm
MLB
-
DSM
2 stops27h 42m
Delta
Deal found 4/30$470
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/255:27 am
DSM
-
MLB
1 stop7h 23m
Delta
Mon 6/15:46 am
MLB
-
DSM
1 stop6h 22m
Delta
Deal found 4/27$476

Find flight deals from Des Moines to Melbourne

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Melbourne (MLB). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 30, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$403
(Delta)

One-way from

$388
(Delta)

Popular in

February

Cheapest in

September

Average price

$356
Provider with most accurate pricing for Des Moines-Melbourne flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Melbourne flights.
Search Deals
From Des Moines to Melbourne
Search Deals
One-way flight from Des Moines to Melbourne
Search Deals
Highest demand for flights based on searches. 12% potential increase in price ($39 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($10 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Melbourne that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2026.
Use the filters below to find and compare flights from Des Moines to Melbourne that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesMelbourne

DSM - MLB

DSMMLB

Des Moines

Sat 8/29

5:45 am-2:24 pm

1 stop7h 39m

Melbourne

Sun 9/6

5:55 am-10:14 am

1 stop5h 19m

$435

Des MoinesMelbourne

DSM - MLB

DSMMLB

Des Moines

Wed 7/22

5:41 am-2:04 pm

1 stop7h 23m

Melbourne

Sun 7/26

5:37 am-10:45 am

1 stop6h 08m

$435

Des MoinesMelbourne

DSM - MLB

DSMMLB

Des Moines

Tue 7/14

5:41 am-2:04 pm

1 stop7h 23m

Melbourne

Sun 7/26

5:37 am-10:45 am

1 stop6h 08m

$435

Des MoinesMelbourne

DSM - MLB

DSMMLB

Des Moines

Sat 8/15

2:15 pm-10:47 pm

1 stop7h 32m

Melbourne

Thu 9/17

5:55 am-10:14 am

1 stop5h 19m

$435
Quickest round-trip

Des MoinesMelbourne

DSM - MLB

DSMMLB

Des Moines

Fri 5/29

11:57 am-6:20 pm

1 stop5h 23m

Melbourne

Sun 5/31

5:46 am-11:08 am

1 stop6h 22m

$435

Des MoinesMelbourne

DSM - MLB

DSMMLB

Des Moines

Fri 8/14

2:15 pm-10:47 pm

1 stop7h 32m

Melbourne

Sat 8/22

6:35 pm-10:26 pm

1 stop4h 51m

$455

Des MoinesMelbourne

DSM - MLB

DSMMLB

Des Moines

Sat 8/15

5:45 am-2:24 pm

1 stop7h 39m

Melbourne

Fri 9/11

6:35 pm-9:17 pm

2 stops27h 42m

$470

Des MoinesMelbourne

DSM - MLB

DSMMLB

Des Moines

Wed 8/12

10:55 am-10:47 pm

2 stops10h 52m

Melbourne

Tue 8/18

6:35 pm-10:26 pm

1 stop4h 51m

$470

Des MoinesMelbourne

DSM - MLB

DSMMLB

Des Moines

Mon 5/25

5:27 am-1:50 pm

1 stop7h 23m

Melbourne

Mon 6/1

5:46 am-11:08 am

1 stop6h 22m

$476

Des MoinesMelbourne

DSM - MLB

DSMMLB

Des Moines

Tue 5/12

6:00 am-5:02 pm

2 stops10h 02m

Melbourne

Sat 5/16

11:54 am-7:33 pm

2 stops8h 39m

$477

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/30

Showing 1-10 of 18 resultsSorted by cheapest first
1
2

Compare providers for flights from Des Moines to Melbourne

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Melbourne in April.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Des Moines-Melbourne, Florida flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Melbourne, Florida flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Melbourne, Florida flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Des Moines-Melbourne, Florida flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Melbourne, Florida flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Melbourne

Have a flexible travel schedule? Discover the best time to fly to Melbourne from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Melbourne. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Des Moines to Melbourne, Florida?

    Delta can get you from Des Moines to Melbourne, Florida in just under 7h 39m. Your travel time can differ by up to . The distance between Des Moines and Melbourne, Florida is about 1182 mi.

  • Can I find deals for flights from Des Moines to Melbourne that include hotel bookings?

    Yes. In addition to deals on Des Moines to Melbourne flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Melbourne?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Melbourne.

  • Can I find deals for business class flights from Des Moines to Melbourne?

    Yes. Cheapflights offers flight deals from Des Moines to Melbourne by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for Des Moines to Melbourne

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