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Santo Domingo

Find cheap American Airlines flights to Santo Domingo

RDU — SDQ
Aug 26 — Sep 21
Wed 8/26
Wed 9/2
1 adult, Economy
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Find American Airlines flight deals to Santo Domingo

Cheapest American Airlines flights from USA to Santo Domingo
Explore the most affordable American Airlines flight options available from USA to Santo Domingo. Find the lowest fares with prices last updated on July 27, 2026.

This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/317:55 pm
MCO
-
SDQ
1 stop17h 05m
American Airlines
Wed 9/309:30 am
SDQ
-
MCO
1 stop8h 33m
American Airlines
Deal found 7/25$430
This American Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/307:30 am
MCO
-
SDQ
1 stop5h 52m
American Airlines
Thu 9/102:15 pm
SDQ
-
MCO
1 stop5h 27m
American Airlines
Deal found 7/22$435
This American Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/244:20 pm
MIA
-
SDQ
Nonstop2h 24m
American Airlines
Mon 8/312:22 pm
SDQ
-
MIA
Nonstop2h 27m
American Airlines
Deal found 7/26$447

Flights to Santo Domingo with American Airlines at a glance

Find detailed information about American Airlines flights from USA to Santo Domingo. Explore the options provided by American Airlines to plan your journey from USA to Santo Domingo. Data last updated July 27, 2026.

Popular in

December

Cheapest in

October

Average price

$520

Round-trip from

$424

One-way from

$206
Highest demand for flights to Santo Domingo with American Airlines; 4% potential price increase.
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Best time to find cheap flights to Santo Domingo with American Airlines; 3% potential price drop.
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Average price for flights to Santo Domingo with American Airlines (round-trip).
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American Airlines
  • American Airlines
  • 10/3-10/12
  • 2 total stops
  • 14h 36m total
  • USA to Santo Domingo
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American Airlines
  • American Airlines
  • 9/18
  • 1 total stop
  • 7h 11m total
  • USA to Santo Domingo
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Cheapflights Insights

Find cheap American Airlines flights to Santo Domingo

How long is the flight to Santo Domingo with American Airlines?

On average, American Airlines flights from the United States to Santo Domingo take 4 hours 4 minutes. Flights to Santo Domingo from other popular cities in the United States will vary in length. Below are a few examples of popular routes and their flight times.

American Airlines weekly flight availability to Santo Domingo

The most flights to Santo Domingo operated by American Airlines are scheduled on a Friday (8 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (7 on average).

When is the best time to book a flight to Santo Domingo with American Airlines?

The best time to book a flight to Santo Domingo with American Airlines is 46 days before departure. On average, fares are higher if you book 82 days before departure.

When is the cheapest time to fly to Santo Domingo with American Airlines?

Users looking for the cheapest American Airlines fares to Santo Domingo should consider flying on Sunday at noon, when prices are typically cheapest. Budget-minded travellers will want to avoid Monday afternoons, when prices are usually at their highest.

FAQs about flights to Santo Domingo with American Airlines

  • Which airport do American Airlines flights arrive at when travelling to Santo Domingo?

    American Airlines flights on this route tend to land at Santo Domingo Las Americas Airport.

  • Is American Airlines the cheapest airline for a flight to Santo Domingo?

    Flight prices will depend on many factors like date, time and cabin class so it is worth comparing flights before booking. Based on Cheapflights data the cheapest average return price for flights to Santo Domingo tends to be with Spirit Airlines.

  • Are there alternative airlines other than American Airlines that fly to Santo Domingo?

    JetBlue, Arajet and Delta all fly to Santo Domingo and offer an alternative to American Airlines.

  • How much is a flight to Santo Domingo with American Airlines?

    The average price for a return flight with American Airlines is $648; with a one-way flight around $316.

See more FAQs

Reviews of American Airlines

See what Cheapflights users have to say about their American Airlines experience.
American Airlines
7.1
Good
10,000 reviews
Overview

Entertainment

6.8

Boarding

7.5

Food

6.4

Comfort

7.2

Crew

7.9

Popular American Airlines flights

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