Santo Domingo

$172+ Cheap flights from Panama City (PTY) to Santo Domingo (SDQ)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/12. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — SDQ
Jul 7 — Jul 141
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Cheapflights Tip: The best prices from Panama City Tocumen Intl to Santo Domingo Las Americas are usually found in July or August, booked 62 days in advance, depart on a Tuesday or Wednesday and return on a Thursday

Cheap flight deals from Panama City to Santo Domingo

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Santo Domingo (SDQ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 2, 2025.

Round-trip from

$310
(Mytrip)

One-way from

$172
(FlightHub)

Popular in

June

Cheapest in

July

Average price

$389

Good round-trip deal

$428 or less
From Panama City Tocumen Intl to Santo Domingo Las Americas
One-way flight from Panama City Tocumen Intl to Santo Domingo Las Americas
High demand for flights, 0% potential price rise
Cheapest flight prices on average. 0% potential price decrease ($2 potential savings vs. average RT price).
Average for round-trip flights in July 2025
Price to beat on a round-trip flight from Panama City Tocumen Intl to Santo Domingo Las Americas.

Find flight deals from Panama City to Santo Domingo

Cheapest flights from Panama City to Santo Domingo
Explore the most affordable flight options available from Panama City to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 2, 2025.

This Mytrip deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/3011:05 amPTY - SDQ
1 stop5h 10mAvianca
Mon 8/411:45 amSDQ - PTY
1 stop5h 45mAvianca
Deal found 6/30$310
This Kiwi.com deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/1511:05 amPTY - SDQ
1 stop5h 10mMultiple Airlines
Mon 8/1812:56 pmSDQ - PTY
2 stops12h 49mMultiple Airlines
Deal found 7/1$448
This Copa Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/3012:44 pmPTY - SDQ
Nonstop2h 33mCopa Airlines
Mon 8/411:54 amSDQ - PTY
Nonstop2h 35mCopa Airlines
Deal found 6/30$450

Cheapflights Fare Finder

Customize your flight search to find flights from Panama City to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 2, 2025.
Use the filters below to find and compare flights from Panama City to Santo Domingo that are best for you.

Fly from

Panama City

Fly to

Santo Domingo

Route

Depart

Return

Price

Panama CitySanto Domingo

PTY - SDQ

PTYSDQ

Panama City Tocumen Intl

Wed 7/30

11:05 am-5:15 pm

1 stop5h 10m

Santo Domingo Las Americas

Mon 8/4

11:45 am-4:30 pm

1 stop5h 45m

$310

Panama CitySanto Domingo

PTY - SDQ

PTYSDQ

Panama City Tocumen Intl

Fri 8/15

11:05 am-5:15 pm

1 stop5h 10m

Santo Domingo Las Americas

Mon 8/18

12:56 pm-12:45 am

2 stops12h 49m

$448

Panama CitySanto Domingo

PTY - SDQ

PTYSDQ

Panama City Tocumen Intl

Wed 7/30

7:26 am-10:59 am

Nonstop2h 33m

Santo Domingo Las Americas

Mon 8/4

8:57 am-10:30 am

Nonstop2h 33m

$450

Panama CitySanto Domingo

PTY - SDQ

PTYSDQ

Panama City Tocumen Intl

Fri 9/12

3:25 am-5:15 pm

1 stop12h 50m

$172

Panama CitySanto Domingo

PTY - SDQ

PTYSDQ

Panama City Tocumen Intl

Mon 7/21

5:25 pm-12:52 am

2 stops30h 27m

$316

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/1

Best time to book a flight from Panama City to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Santo Domingo

How far ahead should I book a flight from Panama City to Santo Domingo?

Use this chart to determine the optimal time to book a round-trip flight from Panama City to Santo Domingo. Price data was last updated on June 27, 2025.

The price you pay for your flight from Panama City to Santo Domingo may vary depending on when you book. For the best chance of a lower fare, look to book 62 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Panama City to Santo Domingo?

Currently, January is the cheapest month in which you can book a flight from Panama City to Santo Domingo (average of $362). Flying from Panama City to Santo Domingo in December is currently the most expensive (average of $583). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PTY to SDQ?

Find hourly flight availability from Panama City to Santo Domingo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 2, 2025.

One of the essential ways to save on airfare from Panama City to Santo Domingo is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the afternoon could potentially save you up to 3% on airfare.

Weekly flight availability from Panama City to Santo Domingo

Explore weekly flight availability from Panama City to Santo Domingo. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated July 2, 2025.

The most flights from PTY to SDQ are scheduled on a Monday (11 on average). You will have fewer flight options on Friday, which is when the least amount of flights are scheduled (3 on average).

Reviews of airlines servicing Santo Domingo

Get insights into the airlines that provide service to Santo Domingo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santo Domingo. Reviews last updated July 2, 2025.
Read through reviews of airlines operating flights from Panama City to Santo Domingo, such as Copa Airlines and Avianca. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Boarding

7.8

Overall

7.5

Comfort

7.4

Crew

8.1

Entertainment

6.8

Food

6.8

Reviews

1 / 20
4.0
Okay

Paul,Jun 2025

PTY - MIA

The boarding process was terrible. No one followed the group numbers. Everyone got up and stood in the tiles upon landing. People kept getting up during the meal and beverage service to go the bathrooms, the crew had to go back and forth in the isles, the service took forever.

Boarding

7.8

Overall

7.5

Comfort

7.4

Crew

8.1

Entertainment

6.8

Food

6.8

Reviews

1 / 20
4.0
Okay

Paul,Jun 2025

PTY - MIA

The boarding process was terrible. No one followed the group numbers. Everyone got up and stood in the tiles upon landing. People kept getting up during the meal and beverage service to go the bathrooms, the crew had to go back and forth in the isles, the service took forever.

Boarding

7.8

Overall

7.5

Comfort

7.4

Crew

8.1

Entertainment

6.8

Food

6.8

Reviews

1 / 20
4.0
Okay

Paul,Jun 2025

PTY - MIA

The boarding process was terrible. No one followed the group numbers. Everyone got up and stood in the tiles upon landing. People kept getting up during the meal and beverage service to go the bathrooms, the crew had to go back and forth in the isles, the service took forever.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airports do I use to fly from Panama City to Santo Domingo?

    If you book a flight from Panama City to Santo Domingo, you will be flying from Tocumen Intl to Las Americas. Flights to Santo Domingo Las Americas (SDQ) from Panama City Tocumen Intl (PTY) take 2h 30m for a nonstop flight. There are 7 flights from Tocumen Intl to Santo Domingo per day from 2 airlines.

  • How popular is this Panama City to Santo Domingo flight route?

  • What are the cheapest airlines flying from Panama City to Santo Domingo round-trip?

    Cheapflights users have booked flights from Panama City to Santo Domingo round-trip from $310. Another airline that can offer you cheap pricing is Copa Airlines. These flights start at 24% lower than the current average price 3 months from now.

  • What are the most reliable airlines from Panama City to Santo Domingo?

    No one likes to see their flight delayed. When booking a flight from Panama City to Santo Domingo consider choosing Copa Airlines (92%), KLM (90%) or Air France (90%) as they are the most reliable in getting you off to your destination on time.

  • What are the cheapest flights from Panama City to Santo Domingo?

    Looking for the cheapest flight from Panama City to Santo Domingo? While on average our users pay $449, our data indicates the cheapest price to be $374. The most popular route (Panama City Tocumen Intl - Santo Domingo Las Americas), is priced around $383.

  • Can I find deals for flights from Panama City to Santo Domingo that include hotel bookings?

    Yes. In addition to deals on Panama City to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Santo Domingo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Santo Domingo.

  • Can I find deals for business class flights from Panama City to Santo Domingo?

    Yes. Cheapflights offers flight deals from Panama City to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Santo Domingo?

    Currently, January is the cheapest month in which you can book a flight from Panama City to Santo Domingo (average of $362). Flying from Panama City to Santo Domingo in December is currently the most expensive (average of $583). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Panama City to Santo Domingo

See prices for flight routes from nearby airports that may be better suited for you.

Top 2 airlines flying from Panama City to Santo Domingo

Discover the top 2 airlines that operate flights from Panama City to Santo Domingo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 2, 2025.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$288Average$350FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$387Average$420FlexibilityNo cancel feeOn-time70%

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