$306+ Cheap flights from Panama City (PTY) to San Francisco (SFO)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/1. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — SFO
Jul 21 — Jul 281
Round-trip
1 adult, Economy
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Find cheap flights from Panama City to San Francisco with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Panama City Tocumen Intl to San Francisco are usually found in September or April, booked 37 days in advance, depart on a Friday or Saturday and return on a Monday
Cheap flight deals from Panama City to San Francisco
Cheapest
Best
Last-minute
One-way
Cheapest flights from Panama City to San FranciscoExplore the most affordable flight options available from Panama City to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 21, 2026.
Explore the most affordable flight options available from Panama City to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 21, 2026.
This Avianca deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/263:50 pm
PTY
- SFO
2 stops16h 35m
Avianca
Sun 8/2311:55 pm
SFO
- PTY
1 stop8h 35m
Avianca
Deal found 6/20![Avianca logo]()
$692
This Avianca deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/125:30 am
PTY
- SFO
1 stop9h 20m
Avianca
Sat 10/2411:55 pm
SFO
- PTY
1 stop17h 00m
Avianca
Deal found 6/20![Avianca logo]()
$693
This Avianca deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/135:30 am
PTY
- SFO
1 stop19h 05m
Avianca
Wed 7/152:15 pm
SFO
- PTY
1 stop9h 40m
Avianca
Deal found 6/18![Avianca logo]()
$703
This Avianca deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/135:30 am
PTY
- SFO
1 stop9h 20m
Avianca
Tue 7/217:45 am
SFO
- PTY
2 stops16h 10m
Avianca
Deal found 6/20![Avianca logo]()
$704
This Avianca deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/1810:10 am
PTY
- SFO
2 stops14h 25m
Avianca
Thu 6/252:15 pm
SFO
- PTY
1 stop9h 40m
Avianca
Deal found 6/17![Avianca logo]()
$715
This Avianca deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/195:30 am
PTY
- SFO
1 stop19h 05m
Avianca
Sat 6/202:15 pm
SFO
- PTY
1 stop18h 15m
Avianca
Deal found 6/18![Avianca logo]()
$716
This Avianca deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/17:50 pm
PTY
- SFO
1 stop19h 10m
Avianca
Sat 12/51:35 am
SFO
- PTY
1 stop14h 20m
Avianca
Deal found 6/18![Avianca logo]()
$724
This oojo deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/1210:10 am
PTY
- SFO
3 stops22h 15m
Avianca
Sat 7/2511:55 pm
SFO
- PTY
1 stop8h 35m
Avianca
Deal found 6/19![Avianca logo]()
$744
This FlightHub deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/133:50 pm
PTY
- SFO
2 stops16h 35m
Avianca
Thu 7/162:30 am
SFO
- PTY
2 stops20h 05m
Avianca
Deal found 6/19![Avianca logo]()
$746
This oojo deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/215:30 am
PTY
- SFO
1 stop9h 20m
Avianca
Thu 6/252:15 pm
SFO
- PTY
1 stop9h 40m
Avianca
Deal found 6/20![Avianca logo]()
$749
This FlightHub deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/273:50 pm
PTY
- SFO
1 stop10h 05m
Avianca
Tue 6/302:15 pm
SFO
- PTY
1 stop9h 40m
Avianca
Deal found 6/16![Avianca logo]()
$750
Best flights from Panama City to San FranciscoDiscover carefully curated flight deals from Panama City to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 21, 2026.
Discover carefully curated flight deals from Panama City to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 21, 2026.
This Avianca deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/263:50 pm
PTY
- SFO
2 stops16h 35m
Avianca
Sun 8/2311:55 pm
SFO
- PTY
1 stop8h 35m
Avianca
Deal found 6/20![Avianca logo]()
$692
This Copa Airlines deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/112:40 pm
PTY
- SFO
Nonstop7h 45m
Copa Airlines
Sun 12/67:36 pm
SFO
- PTY
Nonstop7h 09m
Copa Airlines
Deal found 6/18![Copa Airlines logo]()
$774
This Avianca deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1110:10 am
PTY
- SFO
2 stops14h 25m
Avianca
Fri 9/252:15 pm
SFO
- PTY
1 stop18h 15m
Avianca
Deal found 6/18![Avianca logo]()
$693
This Copa Airlines deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/126:31 pm
PTY
- SFO
Nonstop7h 41m
Copa Airlines
Sun 11/2912:33 am
SFO
- PTY
Nonstop7h 13m
Copa Airlines
Deal found 6/18![Copa Airlines logo]()
$774
This Avianca deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1210:10 am
PTY
- SFO
2 stops14h 25m
Avianca
Sat 10/2411:55 pm
SFO
- PTY
2 stops15h 00m
Avianca
Deal found 6/16![Avianca logo]()
$748
This Copa Airlines deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/96:08 pm
PTY
- SFO
Nonstop7h 32m
Copa Airlines
Tue 9/221:12 am
SFO
- PTY
Nonstop7h 15m
Copa Airlines
Deal found 6/17![Copa Airlines logo]()
$774
This Avianca deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/25:30 am
PTY
- SFO
1 stop9h 20m
Avianca
Sat 9/52:30 am
SFO
- PTY
2 stops28h 45m
Avianca
Deal found 6/20![Avianca logo]()
$777
This Copa Airlines deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/126:08 pm
PTY
- SFO
Nonstop7h 32m
Copa Airlines
Fri 10/231:12 am
SFO
- PTY
Nonstop7h 15m
Copa Airlines
Deal found 6/18![Copa Airlines logo]()
$790
This Copa Airlines deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:08 pm
PTY
- SFO
Nonstop7h 32m
Copa Airlines
Sun 11/87:36 pm
SFO
- PTY
Nonstop7h 10m
Copa Airlines
Deal found 6/17![Copa Airlines logo]()
$790
Last-minute flights from Panama City to San FranciscoDiscover last-minute flight deals from Panama City to San Francisco. Data last updated June 21, 2026 and is based on user searches.
Discover last-minute flight deals from Panama City to San Francisco. Data last updated June 21, 2026 and is based on user searches.
This Avianca deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/1810:10 am
PTY
- SFO
2 stops14h 25m
Avianca
Thu 6/252:15 pm
SFO
- PTY
1 stop9h 40m
Avianca
Deal found 6/17![Avianca logo]()
$715
This Avianca deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/195:30 am
PTY
- SFO
1 stop19h 05m
Avianca
Sat 6/202:15 pm
SFO
- PTY
1 stop18h 15m
Avianca
Deal found 6/18![Avianca logo]()
$716
This oojo deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/215:30 am
PTY
- SFO
1 stop9h 20m
Avianca
Thu 6/252:15 pm
SFO
- PTY
1 stop9h 40m
Avianca
Deal found 6/20![Avianca logo]()
$749
This Trip.com deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/263:50 pm
PTY
- SFO
2 stops16h 35m
Avianca
Mon 6/2911:55 pm
SFO
- PTY
2 stops22h 40m
Avianca
Deal found 6/18![Avianca logo]()
$751
This FlightHub deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/273:50 pm
PTY
- SFO
1 stop10h 05m
Avianca
Tue 6/302:15 pm
SFO
- PTY
1 stop9h 40m
Avianca
Deal found 6/16![Avianca logo]()
$750
This Avianca deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/123:50 pm
PTY
- SFO
2 stops16h 35m
Avianca
Sat 7/2511:55 pm
SFO
- PTY
1 stop8h 35m
Avianca
Deal found 6/20![Avianca logo]()
$693
This Avianca deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/135:30 am
PTY
- SFO
1 stop19h 05m
Avianca
Wed 7/152:15 pm
SFO
- PTY
1 stop9h 40m
Avianca
Deal found 6/18![Avianca logo]()
$703
This Avianca deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/135:30 am
PTY
- SFO
1 stop9h 20m
Avianca
Fri 7/172:15 pm
SFO
- PTY
1 stop18h 15m
Avianca
Deal found 6/19![Avianca logo]()
$704
This Avianca deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/263:50 pm
PTY
- SFO
2 stops16h 35m
Avianca
Sun 8/2311:55 pm
SFO
- PTY
1 stop8h 35m
Avianca
Deal found 6/20![Avianca logo]()
$692
One-way flights from Panama City to San FranciscoSearch for one-way flight options from Panama City to San Francisco. Find affordable one-way fares based on user searches. Data last updated June 21, 2026.
Search for one-way flight options from Panama City to San Francisco. Find affordable one-way fares based on user searches. Data last updated June 21, 2026.
This flugladen.de deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure flugladen.de is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/15:30 am
PTY
- SFO
2 stops17h 10m
Multiple Airlines
Deal found 6/20![Multiple Airlines logo]()
$306
This Kiwi.com deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/283:50 pm
PTY
- SFO
2 stops30h 50m
Multiple Airlines
Deal found 6/17![Multiple Airlines logo]()
$317
This Kiwi.com deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/45:30 am
PTY
- SFO
2 stops17h 00m
Multiple Airlines
Deal found 6/20![Multiple Airlines logo]()
$319
This Kiwi.com deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/193:50 pm
PTY
- SFO
2 stops30h 50m
Multiple Airlines
Deal found 6/17![Multiple Airlines logo]()
$320
This Kiwi.com deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/195:30 am
PTY
- SFO
2 stops17h 56m
Multiple Airlines
Deal found 6/20![Multiple Airlines logo]()
$328
This Kiwi.com deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/183:10 pm
PTY
- SFO
3 stops22h 28m
Multiple Airlines
Deal found 6/17![Multiple Airlines logo]()
$347
This Kiwi.com deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1710:10 am
PTY
- SFO
3 stops27h 28m
Multiple Airlines
Deal found 6/17![Multiple Airlines logo]()
$355
This Kiwi.com deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/173:10 pm
PTY
- SFO
3 stops31h 44m
Multiple Airlines
Deal found 6/17![Multiple Airlines logo]()
$359
This Kiwi.com deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/133:10 pm
PTY
- SFO
3 stops27h 59m
Multiple Airlines
Deal found 6/17![Multiple Airlines logo]()
$361
Find flight deals from Panama City to San Francisco
Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 21, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $692 (Avianca) |
One-way from | $306 (flugladen.de) |
Popular in | February |
Cheapest in | September |
Average price | $762 |
Good round-trip deal | $752 or less |
Good one-way deal | $1,810 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Panama City to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 21, 2026.
Use the filters below to find and compare flights from Panama City to San Francisco that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Panama CitySan Francisco
PTY - SFO
PTYSFO
Panama City Tocumen Intl
Sun 7/26
3:50 pm-6:25 am
2 stops16h 35m
San Francisco
Sun 8/23
11:55 pm-10:30 am
1 stop8h 35m
$692
Panama CitySan Francisco
PTY - SFO
PTYSFO
Panama City Tocumen Intl
Fri 9/11
10:10 am-10:35 pm
2 stops14h 25m
San Francisco
Fri 9/25
2:15 pm-10:30 am
1 stop18h 15m
$693
Panama CitySan Francisco
PTY - SFO
PTYSFO
Panama City Tocumen Intl
Mon 10/12
10:10 am-10:35 pm
2 stops14h 25m
San Francisco
Sat 10/24
11:55 pm-4:55 pm
2 stops15h 00m
$748
Panama CitySan Francisco
PTY - SFO
PTYSFO
Panama City Tocumen Intl
Tue 12/1
12:40 pm-5:25 pm
Nonstop7h 45m
San Francisco
Sun 12/6
7:36 pm-5:45 am
Nonstop7h 09m
$774
Panama CitySan Francisco
PTY - SFO
PTYSFO
Panama City Tocumen Intl
Thu 11/12
6:31 pm-11:12 pm
Nonstop7h 41m
San Francisco
Sun 11/29
12:33 am-10:46 am
Nonstop7h 13m
$774
Panama CitySan Francisco
PTY - SFO
PTYSFO
Panama City Tocumen Intl
Wed 9/9
6:08 pm-11:40 pm
Nonstop7h 32m
San Francisco
Tue 9/22
1:12 am-10:27 am
Nonstop7h 15m
$774
Panama CitySan Francisco
PTY - SFO
PTYSFO
Panama City Tocumen Intl
Wed 9/2
5:30 am-12:50 pm
1 stop9h 20m
San Francisco
Sat 9/5
2:30 am-9:15 am
2 stops28h 45m
$777
Panama CitySan Francisco
PTY - SFO
PTYSFO
Panama City Tocumen Intl
Mon 10/12
6:08 pm-11:40 pm
Nonstop7h 32m
San Francisco
Fri 10/23
1:12 am-10:27 am
Nonstop7h 15m
$790
Quickest round-trip
Panama CitySan Francisco
PTY - SFO
PTYSFO
Panama City Tocumen Intl
Fri 10/30
6:08 pm-11:40 pm
Nonstop7h 32m
San Francisco
Sun 11/8
7:36 pm-5:46 am
Nonstop7h 10m
$790
Cheapest one-way
Panama CitySan Francisco
PTY - SFO
PTYSFO
Panama City Tocumen Intl
Sat 9/19
5:30 am-9:26 pm
2 stops17h 56m
$328
Showing 1-10 of 17 resultsSorted by cheapest first
Compare providers for flights from Panama City to San Francisco
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to San Francisco in June.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Panama City-San Francisco flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City-San Francisco flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City-San Francisco flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Panama City-San Francisco flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Panama City to San Francisco
Have a flexible travel schedule? Discover the best time to fly to San Francisco from Panama City with our price prediction graph.
PTY-SFO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Panama City to San Francisco
Prices
Airlines
How far ahead should I book a flight from Panama City to San Francisco?
The price you pay for your flight from Panama City to San Francisco may vary depending on when you book. For the best chance of a lower fare, look to book 36 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Panama City to San Francisco?
Currently, September is the cheapest month in which you can book a flight from Panama City to San Francisco (average of $609). Flying from Panama City to San Francisco in February is currently the most expensive (average of $793). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from PTY to SFO?
Find hourly flight availability from Panama City to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 21, 2026.
When flying from Panama City to San Francisco, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
The best insider tips for Panama City to San Francisco flights
AI-powered summary based on content written by travel experts. AI can make mistakes.
Cheapflights partnered with top experts to bring you the best recommendations for your Panama City to San Francisco trip
Our travel experts
Reviews of airlines servicing San Francisco
Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated June 21, 2026.
Read through reviews of airlines operating flights from Panama City to San Francisco, such as Copa Airlines,United Airlines, andAvianca. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.4
Crew
8.1
Entertainment
6.8
Boarding
7.8
Food
6.9
Overall
7.6
Reviews
1 / 20
10.0
ExcellentAnonymous,Apr 2026
LIM - PTY
Comfort
7.4
Crew
8.1
Entertainment
6.8
Boarding
7.8
Food
6.9
Overall
7.6
Reviews
1 / 20
10.0
ExcellentAnonymous,Apr 2026
LIM - PTY
Comfort
7.4
Crew
8.1
Entertainment
6.8
Boarding
7.8
Food
6.9
Overall
7.6
Reviews
1 / 20
10.0
ExcellentAnonymous,Apr 2026
LIM - PTY
Comfort
7.4
Crew
8.1
Entertainment
6.8
Boarding
7.8
Food
6.9
Overall
7.6
Reviews
1 / 20
10.0
ExcellentAnonymous,Apr 2026
LIM - PTY
Related info for your journey
Find useful and relevant information for your journey from Panama City to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Francisco?
Book flights to San Francisco if you plan to visit one of these locationsSouth San Francisco
Santa Cruz
Santa Clara
Fairfield
Rancho Cordova
Roseville
Cupertino
Emeryville
Newark
Watsonville
San Bruno
San Ramon
Vacaville
San Carlos
Redwood City
Daly City
Turlock
Sunnyvale
Vallejo
San Lorenzo
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Panama City and San Francisco flights
Browse other Panama City and San Francisco flight options. Last updated on June 21, 2026.
Other flights from Panama City
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Top 3 airlines flying from Panama City to San Francisco
Discover the top 3 airlines that operate flights from Panama City to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 21, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$153 | Average$565 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$359 | Average$692 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$562 | Average$719 | FlexibilityNo cancel fee | On-time69% |