Question 1

What are the most popular destinations to fly to from Panama City?

Accepted Answer

This month, the top selected destinations from Panama City are Bogotá, Madrid, New York John F Kennedy Intl Airport. Throughout the year, Bogotá, Madrid, Bocas del Toro are some of the top choices made by users flying from Panama City.

Question 2

When is the best time to book a flight from Panama City?

Accepted Answer

To ensure you get the cheapest price possible for a flight from Panama City, you should look to book at least 72 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

Question 3

What is the cheapest month to book a flight from Panama City?

Accepted Answer

Currently, May is the cheapest month in which you can book a flight from Panama City (average of $351). Flying from Panama City in October will prove the most costly (average of $468). There are multiple factors that influence the price of a flight so comparing airlines, departure airports and times can help keep costs down.

Question 4

When is the cheapest time to fly from Panama City?

Accepted Answer

Those who are seeking the cheapest fare on flights departing from Panama City would be wise to consider leaving during Wednesday evenings when prices are typically at their lowest. When considering other options, price-conscious travelers should avoid Sunday at noon when fares are usually the most expensive.

Question 5

Which airlines fly from Panama City?

Accepted Answer

For flights departing from Panama City check dates and pricing for the following: Copa Airlines, Avianca, American Airlines. These airlines depart to the following popular destinations: Miami.

Question 6

What are popular destinations to fly to from Panama City?

Accepted Answer

Some of the most frequent flights departing from Panama City everyday are: Sao Paulo (244 flights per day), San José (127 flights per day), and Guatemala City (110 flights per day).

Question 7

What is the cheapest place to fly to from Panama City?

Accepted Answer

The cheapest city to fly to from Panama City is David Enrique Malek, with prices starting at $56. Explore other affordable destinations below.

Question 8

What is the cheapest flight from Panama City to anywhere?

Accepted Answer

Users have flown out of Panama City for as low as $56 to David (prices may vary depending on the airline and departure time). On average, users have booked flights for $663 to fly from Panama City.

Question 9

What are the cheapest airlines flying from Panama City to anywhere?

Accepted Answer

Over the past few days, we've found that Air Panama, Wingo, and Copa Airlines have the cheapest prices from Panama City. Air Panama flights from Panama City to Bocas Del Toro ($66), Wingo flights from Panama City to Barranquilla E Cortissoz ($68), and Copa Airlines flights from Panama City to San Andres Island ($85).

Question 10

What is the cheapest premium economy flight from Panama City?

Accepted Answer

Options for some of the cheapest premium economy flights from Panama City we have found on Cheapflights are as follows:
Fly from Panama City Tocumen Intl to Mexico City Benito Juarez Airport starting at $570
Fly from Panama City Tocumen Intl to Madrid starting at $1,001
Fly from Panama City Tocumen Intl to Austin starting at $1,146
Fly from Panama City Tocumen Intl to Santo Domingo starting at $1,184

Question 11

What is the cheapest first class flight from Panama City?

Accepted Answer

If you’re looking for a cheap first-class flight from Panama City, consider Sao Paulo. Prices start at $20,604 so you can fly first-class even on a budget.

Question 12

What is the cheapest month to fly from Panama City?

Accepted Answer

May is currently the cheapest month to fly from Panama City. At this moment in time October is the most expensive month. These prices are determined by multiple factors and booking in advance can help keep costs down if your schedule is not as flexible.

Question 13

Where are the cheapest places to fly to from Panama City?

Accepted Answer

Check out the cheapest flights from Panama City to embark to:
Fly from Panama City to Bogotá from $137 round trip
Fly from Panama City to Cartagena from $163 round trip
Fly from Panama City to Barranquilla from $215 round trip
Fly from Panama City to Medellín from $225 round trip
Fly from Panama City to San Salvador from $290 round trip

Question 14

E

Accepted Answer

Most accurate provider: Among all the travel providers offering deals on flights from Panama City, FlightHub has been found to have the most accurate pricing. Users can find the same prices on deals on Cheapflights as FlightHub about >95% of the time. This is based on searches for flights from Panama City made on Cheapflights over the past month and is updated monthly.

Question 15

E

Accepted Answer

Most trusted provider: In terms of trustworthiness, Cheapflights users rate FlightHub the highest out of those offering flight deals from Panama City. FlightHub has a user feedback rating of 3 out of 3 stars (3 being the best) and has received the most positive sentiment from Cheapflights users searching for flights from Panama City. This info is gathered from Cheapflights searches over the past month.

Provider	Price Accuracy	Trust Score*
Expedia	Price Accuracy1 star	Trust Score*3 stars
eDreams	Price Accuracy2 stars	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*3 stars
Super.com	Price Accuracy-	Trust Score*3 stars

$78+ Cheap flights from Panama City

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/19. Fares are subject to change and may not be available on all flights or dates of travel.

Find flights from Panama City within your budget

Compare providers for flights from Panama City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City in October

Best time to book a flight from Panama City

Have a flexible travel schedule? Discover the best time to fly from Panama City with our price prediction graph.

Travel insights for flights from Panama City

What is the cheapest month to book a flight from Panama City?

Which airlines fly from Panama City?

For flights departing from Panama City check dates and pricing for the following: Copa Airlines, Avianca, American Airlines. These airlines depart to the following popular destinations: Miami.

What are popular destinations to fly to from Panama City?

Some of the most frequent flights departing from Panama City everyday are: Sao Paulo (244 flights per day), San José (127 flights per day), and Guatemala City (110 flights per day).

What is the cheapest place to fly to from Panama City?

The cheapest city to fly to from Panama City is David Enrique Malek, with prices starting at $56. Explore other affordable destinations below.

When is the best time to book a flight from Panama City?

To ensure you get the cheapest price possible for a flight from Panama City, you should look to book at least 72 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

When is the cheapest time to fly from Panama City?

Use this chart to determine the cheapest time to fly round-trip from Panama City to Miami. Price data was last updated on October 24, 2026.

Airline reviews for flights from Panama City

Read reviews from past customers who have flown Copa Airlines,American Airlines, andAvianca from Panama City. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Browse thousands of different options on Cheapflights for your next trip

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Popular international destinations from Panama City

The most popular international flight routes departing from Panama City we’ve come across at this time.

Airports servicing

Fly out of one of these airports located in .

Fly from other Panama cities

Consider departing from one of these cities also located in Panama. Flight origins are based on user searches made on Cheapflights and were last updated on October 27, 2026.

Popular Round-Trip Flight Destinations

Consider these popular destinations that Cheapflights users have chosen when departing from Panama City. Routes are based on user searches and were last updated on October 27, 2026.

Popular flight searches

Check out other popular destinations found by fellow travelers in 2026

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