$147+ Cheap flights from Panama City (PTY) to Guatemala City (GUA)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/8. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — GUA
Oct 21 — Oct 281
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Panama City to Guatemala City with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Panama City Tocumen Intl to Guatemala City La Aurora are usually found in March or February, booked 83 days in advance, depart on a Tuesday or Thursday and return on a Friday
Cheap flight deals from Panama City to Guatemala City
Cheapest
Best
Last-minute
One-way
Cheapest flights from Panama City to Guatemala CityExplore the most affordable flight options available from Panama City to Guatemala City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 21, 2026.
Explore the most affordable flight options available from Panama City to Guatemala City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 21, 2026.
This Copa Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/38:15 am -
Nonstop2h 24m
Fri 11/63:53 am -
Nonstop2h 28m
Deal found 9/20![Copa Airlines logo]()
$274
This Kiwi.com deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/310:05 am -
1 stop8h 20m
Sun 11/89:20 am -
1 stop6h 55m
Deal found 9/20![Avianca logo]()
$279
This Copa Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/38:15 am -
Nonstop2h 24m
Thu 11/126:19 am -
1 stop13h 01m
Deal found 9/21![Copa Airlines logo]()
$282
This Copa Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/18:15 am -
Nonstop2h 24m
Fri 11/63:53 am -
Nonstop2h 28m
Deal found 9/21![Copa Airlines logo]()
$284
This Avianca deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/3110:05 am -
1 stop8h 20m
Fri 11/69:20 am -
1 stop6h 55m
Deal found 9/16![Avianca logo]()
$285
This Avianca deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/106:10 pm -
1 stop7h 45m
Mon 11/163:40 pm -
1 stop9h 30m
Deal found 9/21![Avianca logo]()
$286
This Kiwi.com deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/410:05 am -
1 stop8h 20m
Sat 11/78:15 pm -
1 stop4h 55m
Deal found 9/20![Avianca logo]()
$287
This Avianca deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/93:55 pm -
1 stop8h 10m
Sun 11/158:15 pm -
1 stop13h 20m
Deal found 9/17![Avianca logo]()
$288
This Kiwi.com deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/210:05 am -
1 stop8h 20m
Sun 11/88:15 pm -
1 stop4h 55m
Deal found 9/20![Avianca logo]()
$290
This Copa Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/109:45 pm -
Nonstop2h 21m
Tue 11/172:22 am -
Nonstop2h 27m
Deal found 9/21![Copa Airlines logo]()
$292
This Kiwi.com deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/25:30 am -
1 stop4h 25m
Sat 11/79:20 am -
1 stop6h 55m
Deal found 9/20![Avianca logo]()
$294
Best flights from Panama City to Guatemala CityDiscover carefully curated flight deals from Panama City to Guatemala City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 21, 2026.
Discover carefully curated flight deals from Panama City to Guatemala City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 21, 2026.
This Copa Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/57:25 am -
Nonstop2h 21m
Tue 11/102:22 am -
Nonstop2h 27m
Deal found 9/18![Copa Airlines logo]()
$274
This Copa Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/318:15 am -
Nonstop2h 22m
Fri 11/63:53 am -
Nonstop2h 28m
Deal found 9/16![Copa Airlines logo]()
$284
This Copa Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/18:15 am -
Nonstop2h 24m
Fri 11/63:53 am -
Nonstop2h 28m
Deal found 9/21![Copa Airlines logo]()
$284
This Copa Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/317:24 am -
Nonstop2h 22m
Fri 11/66:19 am -
1 stop5h 09m
Deal found 9/16![Copa Airlines logo]()
$293
This Copa Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2810:25 am -
Nonstop2h 22m
Wed 11/46:19 am -
1 stop5h 09m
Deal found 9/20![Copa Airlines logo]()
$293
This Copa Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/197:24 am -
Nonstop2h 22m
Wed 10/287:17 am -
Nonstop2h 30m
Deal found 9/20![Copa Airlines logo]()
$295
Last-minute flights from Panama City to Guatemala CityDiscover last-minute flight deals from Panama City to Guatemala City. Data last updated September 21, 2026 and is based on user searches.
Discover last-minute flight deals from Panama City to Guatemala City. Data last updated September 21, 2026 and is based on user searches.
This Avianca deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates ” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/244:25 am -
1 stop13h 35m
Fri 9/255:25 am -
1 stop4h 05m
Deal found 9/18![Avianca logo]()
$297
This Avianca deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/14:25 am -
1 stop13h 35m
Sun 10/48:15 pm -
1 stop4h 40m
Deal found 9/17![Avianca logo]()
$296
This Copa Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1810:25 am -
Nonstop2h 22m
Sun 10/256:24 am -
1 stop5h 04m
Deal found 9/18![Copa Airlines logo]()
$303
This Copa Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/238:11 am -
Nonstop2h 22m
Tue 10/276:24 am -
1 stop3h 45m
Deal found 9/20![Copa Airlines logo]()
$295
This Copa Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/298:15 am -
Nonstop2h 22m
Fri 11/63:53 am -
Nonstop2h 28m
Deal found 9/16![Copa Airlines logo]()
$284
This Copa Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/307:24 am -
Nonstop2h 22m
Mon 11/96:19 am -
1 stop13h 16m
Deal found 9/21![Copa Airlines logo]()
$347
This Avianca deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/3110:05 am -
1 stop8h 20m
Fri 11/69:20 am -
1 stop6h 55m
Deal found 9/16![Avianca logo]()
$285
This Copa Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/317:24 am -
Nonstop2h 22m
Fri 11/66:19 am -
1 stop5h 09m
Deal found 9/16![Copa Airlines logo]()
$293
This Copa Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/3110:25 am -
Nonstop2h 22m
Thu 11/56:19 am -
1 stop9h 25m
Deal found 9/16![Copa Airlines logo]()
$311
This Copa Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/317:24 am -
Nonstop2h 22m
Wed 11/46:19 am -
1 stop13h 01m
Deal found 9/21![Copa Airlines logo]()
$337
One-way flights from Panama City to Guatemala CitySearch for one-way flight options from Panama City to Guatemala City. Find affordable one-way fares based on user searches. Data last updated September 21, 2026.
Search for one-way flight options from Panama City to Guatemala City. Find affordable one-way fares based on user searches. Data last updated September 21, 2026.
This Copa Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/87:25 am -
Nonstop2h 21m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![Copa Airlines logo]()
$147
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/210:05 am -
1 stop8h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![Avianca logo]()
$301
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/194:25 am -
1 stop9h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Avianca logo]()
$304
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:35 pm -
1 stop4h 01m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![Copa Airlines logo]()
$315
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:35 pm -
1 stop4h 01m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/21![Copa Airlines logo]()
$316
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2210:10 am -
1 stop7h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Avianca logo]()
$317
This FlightHub deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/274:10 pm -
1 stop9h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/19![Avianca logo]()
$324
This FlightHub deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/256:10 pm -
1 stop7h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/19![Avianca logo]()
$325
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/208:11 am -
Nonstop2h 22m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Copa Airlines logo]()
$326
This FlightHub deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/215:30 am -
1 stop8h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![Avianca logo]()
$327
This Kiwi.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/28:15 am -
Nonstop2h 24m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/19![Copa Airlines logo]()
$328
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1810:25 am -
Nonstop2h 22m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Copa Airlines logo]()
$329
Find flight deals from Panama City to Guatemala City
Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Guatemala City (GUA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 21, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $274 (Copa Airlines) |
One-way from | $147 (Copa Airlines) |
Popular in | April |
Cheapest in | March |
Average price | $295 |
Good round-trip deal | $295 or less |
Good one-way deal | $157 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Panama City to Guatemala City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 21, 2026.
Use the filters below to find and compare flights from Panama City to Guatemala City that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
Panama CityGuatemala City
PTY Panama City Tocumen Intl - GUA Guatemala City La Aurora
PTYGUA
Panama City Tocumen Intl
Sun 11/8
7:25 am-8:46 am
Nonstop2h 21m
Guatemala City La Aurora
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$147
Panama CityGuatemala City
PTY Panama City Tocumen Intl - GUA Guatemala City La Aurora
PTYGUA
Panama City Tocumen Intl
Thu 11/5
7:25 am-8:46 am
Nonstop2h 21m
Guatemala City La Aurora
Tue 11/10
2:22 am-5:49 am
Nonstop2h 27m
$274
Panama CityGuatemala City
PTY Panama City Tocumen Intl - GUA Guatemala City La Aurora
PTYGUA
Panama City Tocumen Intl
Sat 10/31
8:15 am-9:37 am
Nonstop2h 22m
Guatemala City La Aurora
Fri 11/6
3:53 am-7:21 am
Nonstop2h 28m
$284
Panama CityGuatemala City
PTY Panama City Tocumen Intl - GUA Guatemala City La Aurora
PTYGUA
Panama City Tocumen Intl
Sun 11/1
8:15 am-9:39 am
Nonstop2h 24m
Guatemala City La Aurora
Fri 11/6
3:53 am-7:21 am
Nonstop2h 28m
$284
Panama CityGuatemala City
PTY Panama City Tocumen Intl - GUA Guatemala City La Aurora
PTYGUA
Panama City Tocumen Intl
Sat 10/31
7:24 am-8:46 am
Nonstop2h 22m
Guatemala City La Aurora
Fri 11/6
6:19 am-12:28 pm
1 stop5h 09m
$293
Panama CityGuatemala City
PTY Panama City Tocumen Intl - GUA Guatemala City La Aurora
PTYGUA
Panama City Tocumen Intl
Wed 10/28
10:25 am-11:47 am
Nonstop2h 22m
Guatemala City La Aurora
Wed 11/4
6:19 am-12:28 pm
1 stop5h 09m
$293
Panama CityGuatemala City
PTY Panama City Tocumen Intl - GUA Guatemala City La Aurora
PTYGUA
Panama City Tocumen Intl
Mon 10/19
7:24 am-8:46 am
Nonstop2h 22m
Guatemala City La Aurora
Wed 10/28
7:17 am-10:47 am
Nonstop2h 30m
$295
Panama CityGuatemala City
PTY Panama City Tocumen Intl - GUA Guatemala City La Aurora
PTYGUA
Panama City Tocumen Intl
Tue 10/13
6:35 pm-9:36 pm
1 stop4h 01m
Guatemala City La Aurora
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$315
Panama CityGuatemala City
PTY Panama City Tocumen Intl - GUA Guatemala City La Aurora
PTYGUA
Panama City Tocumen Intl
Tue 11/3
7:25 am-8:46 am
Nonstop2h 21m
Guatemala City La Aurora
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$336
Panama CityGuatemala City
PTY Panama City Tocumen Intl - GUA Guatemala City La Aurora
PTYGUA
Panama City Tocumen Intl
Sun 11/15
9:45 pm-11:06 pm
Nonstop2h 21m
Guatemala City La Aurora
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$336
Showing 1-10 of 16 resultsSorted by cheapest first
- Most accurate provider: When it comes to deals on Panama City-Guatemala City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City-Guatemala City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City-Guatemala City flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Panama City-Guatemala City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City-Guatemala City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Panama City to Guatemala City
Have a flexible travel schedule? Discover the best time to fly to Guatemala City from Panama City with our price prediction graph.
PTY-GUA
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Panama City to Guatemala City
Prices
Airlines
Delays
How far ahead should I book a flight from Panama City to Guatemala City?
To ensure you get the cheapest price possible for a flight from Panama City to Guatemala City, you should look to book at least 82 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
What is the cheapest month to book a flight from Panama City to Guatemala City?
Currently, March is the cheapest month in which you can book a flight from Panama City to Guatemala City (average of $276). Flying from Panama City to Guatemala City in April is currently the most expensive (average of $312). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from PTY to GUA?
Find hourly flight availability from Panama City to Guatemala City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 21, 2026.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Panama City to Guatemala City as you normally would.
How often are flights from Panama City to Guatemala City delayed?
About 5% of weekly flights between Panama City and Guatemala City have experienced delays in the past year, with the average delay time being 110 minutes.
What is the most punctual flight time for Panama City to Guatemala City flights?
Historically, flights departing in the evening are less likely to be delayed, whereas flights leaving in the early afternoon tend to experience delays more often.
What day of the week experiences the fewest flight delays on this route?
Tuesday tends to have the lowest number of delays on this route, whereas Thursday has historically faced a higher average of delays compared to other days of the week.
Which airline has the best punctuality record on Panama City to Guatemala City flights?
Over the last year, Copa Airlines have had the lowest number of delays on this route, with just 5% of flights being delayed.
The best insider tips for Panama City to Guatemala City flights
AI-powered summary based on content written by travel experts. AI can make mistakes.
Cheapflights partnered with top experts to bring you the best recommendations for your Panama City to Guatemala City trip
Our travel experts
Reviews of airlines servicing Guatemala City
Get insights into the airlines that provide service to Guatemala City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guatemala City. Reviews last updated September 21, 2026.
Peruse reviews from past customers who have flown with Copa Airlines and Avianca from Panama City to Guatemala City to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
7.8
Comfort
7.4
Entertainment
6.9
Crew
8.1
Overall
7.6
Food
6.9
Reviews
1 / 20
2.0
MediocreMaria,Dec 2025
PTY - SLA
Boarding
7.8
Comfort
7.4
Entertainment
6.9
Crew
8.1
Overall
7.6
Food
6.9
Reviews
1 / 20
2.0
MediocreMaria,Dec 2025
PTY - SLA
Boarding
7.8
Comfort
7.4
Entertainment
6.9
Crew
8.1
Overall
7.6
Food
6.9
Reviews
1 / 20
2.0
MediocreMaria,Dec 2025
PTY - SLA
Related info for your journey
Find useful and relevant information for your journey from Panama City to Guatemala City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Guatemala City?
Book flights to Guatemala City if you plan to visit one of these locationsAntigua
Panajachel
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Complete your trip
Flights by cabin class
Guatemala City flight routes
Other flight options
Other flights from Panama City
Popular flights
Complete your trip
Complete your trip to Guatemala City by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Panama City to Guatemala City by cabin class
Find flights from Panama City to Guatemala City, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Guatemala City
Explore flights to Guatemala City departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 21, 2026.
Panama City and Guatemala City flights
Browse other Panama City and Guatemala City flight options. Last updated on September 21, 2026.
Other flights from Panama City
Browse through other flights departing from Panama City. Flights are based on user searches made on Cheapflights and were last updated on September 21, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Panama City to Guatemala City
Discover the top 2 airlines that operate flights from Panama City to Guatemala City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 21, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$163 | Average$289 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$237 | Average$296 | FlexibilityNo cancel fee | On-time70% |