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$274+ Cheap flights from Panama City (PTY) to San Diego (SAN)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/2. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — SAN
Jun 23 — Jun 301
Mon 6/23
Mon 6/30
1 adult, Economy
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Cheap flight deals from Panama City to San Diego

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 18, 2025.

Round-trip from

$361
(United Airlines)

One-way from

$274
(Kiwi.com)

Popular in

December

Cheapest in

July

Average price

$674

Good round-trip deal

$200 or less

Good one-way deal

$296 or less
From Panama City Tocumen Intl to San Diego
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One-way flight from Panama City Tocumen Intl to San Diego
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Highest demand for flights based on searches. 8% potential increase in price ($59 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($10 potential savings vs. average RT price).
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Average for round-trip flights in June 2025
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Price to beat on a round-trip flight from Panama City Tocumen Intl to San Diego.
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Price to beat on a one-way flight from Panama City Tocumen Intl to San Diego.
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Find flight deals from Panama City to San Diego

Cheapest flights from Panama City to San Diego
Explore the most affordable flight options available from Panama City to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 18, 2025.

This United Airlines deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/163:30 pmPTY - SAN
2 stops18h 25mUnited Airlines
Tue 9/306:00 pmSAN - PTY
3 stops22h 37mUnited Airlines
Deal found 6/18$361
This Delta deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/38:10 amPTY - SAN
1 stop15h 05mDelta
Mon 8/1110:30 pmSAN - PTY
1 stop12h 20mDelta
Deal found 6/17$458
This American Airlines deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/33:10 pmPTY - SAN
2 stops24h 27mAmerican Airlines
Sat 8/163:07 pmSAN - PTY
2 stops21h 23mAmerican Airlines
Deal found 6/17$504
This Copa Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/101:15 pmPTY - SAN
Nonstop6h 29mCopa Airlines
Fri 8/159:03 pmSAN - PTY
Nonstop6h 22mCopa Airlines
Deal found 6/16$562
This Kiwi.com deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/99:34 amPTY - SAN
2 stops25h 30mMultiple Airlines
Sun 8/109:03 pmSAN - PTY
Nonstop6h 22mMultiple Airlines
Deal found 6/17$694
This Avianca deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/183:40 pmPTY - SAN
2 stops20h 28mAvianca
Thu 7/248:44 pmSAN - PTY
3 stops35h 41mAvianca
Deal found 6/16$937

Cheapflights Fare Finder

Customize your flight search to find flights from Panama City to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 18, 2025.
Use the filters below to find and compare flights from Panama City to San Diego that are best for you.

Fly from

Panama City

Fly to

San Diego

Route

Depart

Return

Price

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

Tue 9/16

3:30 pm-7:55 am

2 stops18h 25m

San Diego

Tue 9/30

6:00 pm-6:37 pm

3 stops22h 37m

$361

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

Sun 8/3

8:10 am-9:15 pm

1 stop15h 05m

San Diego

Mon 8/11

10:30 pm-12:50 pm

1 stop12h 20m

$458

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

Sun 8/3

3:10 pm-1:37 pm

2 stops24h 27m

San Diego

Sat 8/16

3:07 pm-2:30 pm

2 stops21h 23m

$504

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

Sun 8/10

1:15 pm-5:44 pm

Nonstop6h 29m

San Diego

Fri 8/15

9:03 pm-5:25 am

Nonstop6h 22m

$562

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

Sat 8/9

9:34 am-9:04 am

2 stops25h 30m

San Diego

Sun 8/10

9:03 pm-5:25 am

Nonstop6h 22m

$694

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

Fri 7/18

3:40 pm-10:08 am

2 stops20h 28m

San Diego

Thu 7/24

8:44 pm-10:25 am

3 stops35h 41m

$937

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

Wed 7/2

5:25 pm-7:13 am

3 stops39h 48m

$274

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

Thu 10/30

3:41 pm-11:01 am

1 stop21h 20m

$316

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

Fri 6/27

1:15 pm-5:54 pm

Nonstop6h 39m

$436

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

Thu 10/30

8:05 pm-11:44 pm

3 stops29h 39m

$561

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/17

Best time to book a flight from Panama City to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to San Diego

What is the cheapest month to book a flight from Panama City to San Diego?

Currently, August is the cheapest month in which you can book a flight from Panama City to San Diego (average of $286). Flying from Panama City to San Diego in March is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PTY to SAN?

Find hourly flight availability from Panama City to San Diego. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 18, 2025.

It’s optimal to fly from Panama City to San Diego at noon. By choosing this option you can save up to 77% on the cost of your flight, compared to a flight in the evening.

Rainfall in San Diego by month

Plan your trip to San Diego by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in San Diego ranges from 0.0 - 2.3 inches per month. February is typically the wettest month, when rainfall can reach 2.3 in. July is typically the driest time to visit San Diego when rainfall is around 0.0 in.

Temperature in San Diego by month

Plan your trip to San Diego by taking into account the average temperature totals by month.

If weather is an important factor for your trip to San Diego, use this chart to help with planning. For those seeking warmer temperatures, August is the ideal time of year to visit, when temperatures reach an average of 71.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 57.2 F).

Reviews of airlines servicing San Diego

Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated June 18, 2025.
Read reviews from past customers who have flown Delta, Copa Airlines and United Airlines from Panama City to San Diego. In addition to providing an overall rating, users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,964 reviews

Crew

8.5

Entertainment

7.9

Overall

8.0

Boarding

8.2

Comfort

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Delta
8.0
Very good
7,964 reviews
Delta
8.0
Very good
7,964 reviews

Crew

8.5

Entertainment

7.9

Overall

8.0

Boarding

8.2

Comfort

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Copa Airlines
7.5
Good
1,455 reviews
Delta
8.0
Very good
7,964 reviews

Crew

8.5

Entertainment

7.9

Overall

8.0

Boarding

8.2

Comfort

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
United Airlines
7.4
Good
8,810 reviews
Delta
8.0
Very good
7,964 reviews

Crew

8.5

Entertainment

7.9

Overall

8.0

Boarding

8.2

Comfort

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,964 reviews

Crew

8.5

Entertainment

7.9

Overall

8.0

Boarding

8.2

Comfort

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Avianca
6.7
Okay
2,350 reviews
Delta
8.0
Very good
7,964 reviews

Crew

8.5

Entertainment

7.9

Overall

8.0

Boarding

8.2

Comfort

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Panama City to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Panama City to San Diego round-trip?

    United Airlines, at $361, was found to be the cheapest airline from Panama City to San Diego.Alternate airlines to your destination round-trip include Delta and American Airlines. Users have found that United Airlines is 43% cheaper than the other options available to this destination.

  • What are the cheapest airlines to fly from Panama City to San Diego one-way?

    $316 is the cheapest one-way deal found within the past few days, from United Airlines. You may also be able to find cheap deals on Copa Airlines and Avianca, with prices starting from $436 and $561, respectively.

  • What are the cheapest flights from Panama City to San Diego?

    On average you can expect to pay $390 for a flight from Panama City to San Diego. The cheapest flight overall is $200 while the most popular route, (Panama City Tocumen Intl - San Diego) is currently priced at $421.

  • Can I find deals for flights from Panama City to San Diego that include hotel bookings?

    Yes. In addition to deals on Panama City to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to San Diego.

  • Can I find deals for business class flights from Panama City to San Diego?

    Yes. Cheapflights offers flight deals from Panama City to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to San Diego?

    Currently, August is the cheapest month in which you can book a flight from Panama City to San Diego (average of $286). Flying from Panama City to San Diego in March is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
El Cajon
Chula Vista
National City
Lemon Grove
Imperial Beach
La Mesa
Alpine
Poway
Santee
Coronado

Browse thousands of different options on Cheapflights for your next trip

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Top airline flying from Panama City to San Diego

Discover the top airline that operate flights from Panama City to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$450Average$618FlexibilityNo cancel feeOn-time69%

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