$363+ Cheap flights from Panama City (PTY) to San Diego (SAN)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/23. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — SAN
Oct 7 — Oct 141
Round-trip
1 adult, Economy
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Find cheap flights from Panama City to San Diego with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Panama City to San Diego
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Best
Last-minute
One-way
Cheapest flights from Panama City to San DiegoExplore the most affordable flight options available from Panama City to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 7, 2026.
Explore the most affordable flight options available from Panama City to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 7, 2026.
This United Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/213:30 pm -
2 stops22h 48m
Sun 10/254:45 pm -
2 stops23h 53m
Deal found 9/2![United Airlines logo]()
$599
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/283:41 pm -
1 stop31h 45m
Tue 11/38:05 am -
1 stop8h 33m
Deal found 9/6![United Airlines logo]()
$669
This United Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/133:30 pm -
2 stops22h 05m
Fri 9/187:41 pm -
2 stops20h 56m
Deal found 9/2![United Airlines logo]()
$708
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/263:41 pm -
2 stops19h 29m
Fri 10/308:05 am -
1 stop8h 33m
Deal found 9/4![United Airlines logo]()
$721
This United Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2010:00 am -
1 stop13h 24m
Tue 10/278:05 am -
1 stop8h 33m
Deal found 9/5![United Airlines logo]()
$726
This United Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/153:30 pm -
1 stop31h 54m
Tue 9/223:04 pm -
1 stop21h 10m
Deal found 9/5![United Airlines logo]()
$765
Best flights from Panama City to San DiegoDiscover carefully curated flight deals from Panama City to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 7, 2026.
Discover carefully curated flight deals from Panama City to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 7, 2026.
This United Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/213:30 pm -
2 stops22h 48m
Sun 10/254:45 pm -
2 stops23h 53m
Deal found 9/2![United Airlines logo]()
$599
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/287:55 am -
2 stops14h 41m
Tue 11/38:05 am -
1 stop8h 33m
Deal found 9/6![United Airlines logo]()
$669
This United Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/153:30 pm -
2 stops26h 24m
Tue 9/228:00 am -
1 stop8h 37m
Deal found 9/2![United Airlines logo]()
$708
This United Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/133:30 pm -
2 stops22h 05m
Fri 9/187:41 pm -
2 stops20h 56m
Deal found 9/2![United Airlines logo]()
$708
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/263:41 pm -
2 stops19h 29m
Fri 10/308:05 am -
1 stop8h 33m
Deal found 9/4![United Airlines logo]()
$721
Last-minute flights from Panama City to San DiegoDiscover last-minute flight deals from Panama City to San Diego. Data last updated September 7, 2026 and is based on user searches.
Discover last-minute flight deals from Panama City to San Diego. Data last updated September 7, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/133:30 pm -
2 stops22h 05m
Fri 9/187:41 pm -
2 stops20h 56m
Deal found 9/2![United Airlines logo]()
$708
This United Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/153:30 pm -
1 stop31h 54m
Tue 9/223:04 pm -
1 stop21h 10m
Deal found 9/5![United Airlines logo]()
$765
This United Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2010:00 am -
1 stop13h 24m
Tue 10/278:05 am -
1 stop8h 33m
Deal found 9/5![United Airlines logo]()
$726
This United Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/213:30 pm -
2 stops22h 48m
Sun 10/254:45 pm -
2 stops23h 53m
Deal found 9/2![United Airlines logo]()
$599
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/263:41 pm -
2 stops19h 29m
Fri 10/308:05 am -
1 stop8h 33m
Deal found 9/4![United Airlines logo]()
$721
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/283:41 pm -
1 stop31h 45m
Tue 11/38:05 am -
1 stop8h 33m
Deal found 9/6![United Airlines logo]()
$669
One-way flights from Panama City to San DiegoSearch for one-way flight options from Panama City to San Diego. Find affordable one-way fares based on user searches. Data last updated September 7, 2026.
Search for one-way flight options from Panama City to San Diego. Find affordable one-way fares based on user searches. Data last updated September 7, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/231:48 pm -
Nonstop6h 42m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/4![Copa Airlines logo]()
$363
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/263:41 pm -
2 stops23h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![United Airlines logo]()
$367
This Kiwi.com deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/153:39 pm -
2 stops34h 17m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/2![Multiple Airlines logo]()
$428
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/309:48 pm -
2 stops28h 03m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Multiple Airlines logo]()
$429
This Kiwi.com deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/239:33 pm -
3 stops21h 16m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/4![Multiple Airlines logo]()
$430
This Kiwi.com deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/279:33 pm -
3 stops45h 26m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/2![Multiple Airlines logo]()
$434
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/269:31 pm -
3 stops23h 07m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![Multiple Airlines logo]()
$438
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/249:33 pm -
2 stops28h 23m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![Multiple Airlines logo]()
$449
This Kiwi.com deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/49:33 pm -
3 stops22h 36m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![Multiple Airlines logo]()
$457
This Kiwi.com deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1210:25 am -
3 stops16h 32m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![Multiple Airlines logo]()
$459
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/228:01 am -
3 stops31h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![Multiple Airlines logo]()
$471
Find flight deals from Panama City to San Diego
Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 7, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $599 (United Airlines) |
One-way from | $363 (Kiwi.com) |
Popular in | June |
Cheapest in | November |
Average price | $692 |
Good round-trip deal | $365 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Panama City to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 7, 2026.
Use the filters below to find and compare flights from Panama City to San Diego that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
Panama CitySan Diego
PTY Panama City Tocumen Intl - SAN San Diego
PTYSAN
Panama City Tocumen Intl
Fri 10/23
1:48 pm-6:30 pm
Nonstop6h 42m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$363
Panama CitySan Diego
PTY Panama City Tocumen Intl - SAN San Diego
PTYSAN
Panama City Tocumen Intl
Mon 10/26
3:41 pm-12:56 pm
2 stops23h 15m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$367
Panama CitySan Diego
PTY Panama City Tocumen Intl - SAN San Diego
PTYSAN
Panama City Tocumen Intl
Thu 11/12
4:41 pm-11:31 am
2 stops21h 50m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$367
Panama CitySan Diego
PTY Panama City Tocumen Intl - SAN San Diego
PTYSAN
Panama City Tocumen Intl
Tue 10/27
3:41 pm-11:31 am
2 stops21h 50m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$367
Panama CitySan Diego
PTY Panama City Tocumen Intl - SAN San Diego
PTYSAN
Panama City Tocumen Intl
Thu 10/15
3:39 pm-11:56 pm
2 stops34h 17m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$428
Panama CitySan Diego
PTY Panama City Tocumen Intl - SAN San Diego
PTYSAN
Panama City Tocumen Intl
Fri 10/23
8:57 am-7:47 pm
1 stop12h 50m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$507
Panama CitySan Diego
PTY Panama City Tocumen Intl - SAN San Diego
PTYSAN
Panama City Tocumen Intl
Wed 9/30
8:06 am-6:09 pm
3 stops36h 03m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$509
Panama CitySan Diego
PTY Panama City Tocumen Intl - SAN San Diego
PTYSAN
Panama City Tocumen Intl
Thu 10/15
3:30 pm-3:40 pm
1 stop26h 10m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$540
Panama CitySan Diego
PTY Panama City Tocumen Intl - SAN San Diego
PTYSAN
Panama City Tocumen Intl
Fri 10/9
3:50 pm-8:08 pm
2 stops30h 18m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$570
Panama CitySan Diego
PTY Panama City Tocumen Intl - SAN San Diego
PTYSAN
Panama City Tocumen Intl
Wed 10/21
3:30 pm-12:18 pm
2 stops22h 48m
San Diego
Sun 10/25
4:45 pm-6:38 pm
2 stops23h 53m
$599
Showing 1-10 of 14 resultsSorted by cheapest first
- Most accurate provider: When it comes to deals on Panama City-San Diego flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City-San Diego flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City-San Diego flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Panama City-San Diego flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City-San Diego flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Panama City to San Diego
Have a flexible travel schedule? Discover the best time to fly to San Diego from Panama City with our price prediction graph.
PTY-SAN
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Panama City to San Diego
What is the cheapest month to book a flight from Panama City to San Diego?
Currently, November is the cheapest month in which you can book a flight from Panama City to San Diego (average of $434). Flying from Panama City to San Diego in June is currently the most expensive (average of $1,217). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from PTY to SAN?
Find hourly flight availability from Panama City to San Diego. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 7, 2026.
When flying from Panama City to San Diego, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
Reviews of airlines servicing San Diego
Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated September 7, 2026.
Peruse reviews from past customers who have flown with Copa Airlines and United Airlines from Panama City to San Diego to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.1
Entertainment
6.9
Overall
7.6
Boarding
7.8
Comfort
7.4
Food
6.9
Reviews
1 / 20
2.0
MediocreMaria,Dec 2025
PTY - SLA
Crew
8.1
Entertainment
6.9
Overall
7.6
Boarding
7.8
Comfort
7.4
Food
6.9
Reviews
1 / 20
2.0
MediocreMaria,Dec 2025
PTY - SLA
Crew
8.1
Entertainment
6.9
Overall
7.6
Boarding
7.8
Comfort
7.4
Food
6.9
Reviews
1 / 20
2.0
MediocreMaria,Dec 2025
PTY - SLA
Related info for your journey
Find useful and relevant information for your journey from Panama City to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Diego?
Book flights to San Diego if you plan to visit one of these locationsEl Cajon
National City
Chula Vista
Coronado
Poway
San Ysidro
La Mesa
Santee
Julian
Lemon Grove
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Panama City and San Diego flights
Browse other Panama City and San Diego flight options. Last updated on September 7, 2026.
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Check out other popular destinations found by fellow travelers in 2026
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Explore flights to San Diego departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 7, 2026.
Top 2 airlines flying from Panama City to San Diego
Discover the top 2 airlines that operate flights from Panama City to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 7, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$339 | Average$755 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$460 | Average$714 | FlexibilityNo cancel fee | On-time70% |