What are the cheapest airlines flying from San Diego to Panama City round-trip?

According to our current data, United Airlines ($339), Copa Airlines ($341), and Delta ($365) offers the cheapest pricing from San Diego to Panama City. United Airlines is currently priced 44% below the average price you’ll pay for this route.

What are the cheapest airlines to fly from San Diego to Panama City one-way?

The cheapest airline one-way is Copa Airlines, with whom users have recently found tickets for as low as $141. However, be on the lookout for offers from Delta and United Airlines, as they are both options that can get you from San Diego to Panama City for a low price.

What is the cheapest day to fly from San Diego to Panama City?

Travelers seeking maximum savings on their San Diego to Panama City flight should consider departing on Wednesday evenings when fares are most often at their lowest. Friday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

In terms of precipitation, rainfall in Panama City ranges from 0.4 - 13.4 inches per month. October is typically the wettest month, when rainfall can reach 13.4 in. February is typically the driest time to visit Panama City when rainfall is around 0.4 in.

If weather is an important factor for your trip to Panama City, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 78.8 F).

What are the cheapest flights from San Diego to Panama City?

While on average a flight from San Diego to Panama City is generally $1,478, our data shows the cheapest flight currently is $172. When looking at the most popular route, (San Diego - Panama City Tocumen Intl), you can expect to pay $339 for that flight.

What are the most popular airlines that fly from San Diego to Panama City?

American Airlines, Copa Airlines and Delta are the most popular airlines when flying from San Diego to Panama City.

What is the cheapest day to fly round-trip from San Diego to Panama City?

Users have found that leaving on a Tuesday can be a cost-effective option. It’s possible to save up to 37% on your flight compared to booking on days when demand is much higher.

How far in advance should I book a flight from San Diego to Panama City?

Travelers have found it’s best to book a flight 49 days in advance to save up to 124% compared to booking the same week of travel. As your travel date approaches, the cost of this flight route may potentially increase. While opting to book 49 days out may not be an option for all, there are still additional ways to secure a deal in the near future. You might find a flight from San Diego to Panama City 1-2 weeks in advance for as low as $638, or $673 for flights within the next 24 hours.

What is the cheapest month to fly from San Diego to Panama City?

The best pricing can be found in the month of September. Prices to Panama City from San Diego average $610. You can even find prices in September for less than $610, as users have found deals to Panama City from as low as $213. The month of December appears to be one of the more expensive times to travel to Panama City from San Diego. Flying in the targeted month can save you up to 21%.

Can I find deals for flights from San Diego to Panama City that include hotel bookings?

Yes. In addition to deals on San Diego to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from San Diego to Panama City?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Diego to Panama City.

Can I find deals for business class flights from San Diego to Panama City?

Yes. Cheapflights offers flight deals from San Diego to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$141+ Flights from San Diego to Panama City

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1. Tell us where you want to go

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Cheapflights Tip: The best prices from San Diego to Panama City Tocumen Intl are usually found in September or July, booked 88 days in advance, depart on a Wednesday or Friday and return on a Monday

Cheap flight deals from San Diego to Panama City

Round-trip from	$339 (Trip.com)
One-way from	$141 (Copa Airlines)
Popular in	December
Cheapest in	September
Average price	$493
Good round-trip deal	$458 or less
Good one-way deal	$211 or less

From San Diego to Panama City Tocumen Intl

Search Deals

One-way flight from San Diego to Panama City Tocumen Intl

Search Deals

Highest demand for flights based on searches. 12% potential increase in price ($84 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 2% potential price decrease ($12 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in July 2025

Search Deals

Price to beat on a round-trip flight from San Diego to Panama City Tocumen Intl.

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Price to beat on a one-way flight from San Diego to Panama City Tocumen Intl.

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Find flight deals from San Diego to Panama City

Cheapest flights from San Diego to Panama City
Explore the most affordable flight options available from San Diego to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 3, 2025.

Tue 8/266:15 amSAN - PTY

1 stop10h 22mUnited Airlines

Tue 9/93:35 pmPTY - SAN

1 stop10h 40mUnited Airlines

Deal found 7/2

$339

Fri 8/159:03 pmSAN - PTY

Nonstop6h 22mCopa Airlines

Fri 8/291:15 pmPTY - SAN

Nonstop6h 29mCopa Airlines

Deal found 7/3

$341

Sun 9/149:50 pmSAN - PTY

1 stop13h 05mDelta

Sat 9/272:10 pmPTY - SAN

1 stop29h 57mDelta

Deal found 7/1

$365

Fri 8/17:30 pmSAN - PTY

2 stops15h 24mAmerican Airlines

Sun 8/31:55 pmPTY - SAN

2 stops21h 01mAmerican Airlines

Deal found 7/1

$473

Sun 8/179:03 pmSAN - PTY

Nonstop6h 22mMultiple Airlines

Sat 8/233:20 amPTY - SAN

2 stops32h 48mMultiple Airlines

Deal found 7/3

$522

Best flights from San Diego to Panama City
Discover carefully curated flight deals from San Diego to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 3, 2025.

Tue 8/266:15 amSAN - PTY

1 stop10h 22mUnited Airlines

Tue 9/93:35 pmPTY - SAN

1 stop10h 40mUnited Airlines

Deal found 7/2

$339

Fri 8/159:03 pmSAN - PTY

Nonstop6h 22mCopa Airlines

Fri 8/291:15 pmPTY - SAN

Nonstop6h 29mCopa Airlines

Deal found 7/3

$341

Sun 9/149:50 pmSAN - PTY

1 stop13h 05mDelta

Sat 9/272:10 pmPTY - SAN

1 stop29h 57mDelta

Deal found 7/1

$365

Fri 8/17:30 pmSAN - PTY

2 stops15h 24mAmerican Airlines

Sun 8/31:55 pmPTY - SAN

2 stops21h 01mAmerican Airlines

Deal found 7/1

$473

Sun 8/179:03 pmSAN - PTY

Nonstop6h 22mMultiple Airlines

Sat 8/233:20 amPTY - SAN

2 stops32h 48mMultiple Airlines

Deal found 7/3

$522

Last-minute flights from San Diego to Panama City
Discover last-minute flight deals from San Diego to Panama City. Data last updated July 3, 2025 and is based on user searches.

Wed 7/94:24 pmSAN - PTY

2 stops18h 30mAmerican Airlines

Wed 7/301:55 pmPTY - SAN

2 stops21h 01mAmerican Airlines

Deal found 7/1

$592

Wed 7/99:03 pmSAN - PTY

Nonstop6h 22mCopa Airlines

Wed 7/161:15 pmPTY - SAN

Nonstop6h 29mCopa Airlines

Deal found 7/1

$646

Wed 7/99:03 pmSAN - PTY

Nonstop6h 22mMultiple Airlines

Thu 7/103:40 pmPTY - SAN

2 stops26h 38mMultiple Airlines

Deal found 7/1

$785

Wed 7/98:44 pmSAN - PTY

2 stops17h 31mAvianca

Thu 7/108:10 pmPTY - SAN

3 stops29h 34mAvianca

Deal found 7/1

$1,217

Fri 7/118:00 amSAN - PTY

1 stop10h 10mUnited Airlines

Wed 7/303:35 pmPTY - SAN

1 stop19h 03mUnited Airlines

Deal found 7/1

$532

Thu 7/1710:30 pmSAN - PTY

1 stop19h 01mDelta

Sat 7/268:10 amPTY - SAN

1 stop15h 25mDelta

Deal found 6/30

$541

Fri 8/17:30 pmSAN - PTY

2 stops15h 24mAmerican Airlines

Sun 8/31:55 pmPTY - SAN

2 stops21h 01mAmerican Airlines

Deal found 7/1

$473

Fri 8/159:03 pmSAN - PTY

Nonstop6h 22mCopa Airlines

Fri 8/291:15 pmPTY - SAN

Nonstop6h 29mCopa Airlines

Deal found 7/3

$341

Sun 8/179:03 pmSAN - PTY

Nonstop6h 22mMultiple Airlines

Sat 8/233:20 amPTY - SAN

2 stops32h 48mMultiple Airlines

Deal found 7/3

$522

Tue 8/266:15 amSAN - PTY

1 stop10h 22mUnited Airlines

Tue 9/93:35 pmPTY - SAN

1 stop10h 40mUnited Airlines

Deal found 7/2

$339

One-way flights from San Diego to Panama City
Search for one-way flight options from San Diego to Panama City. Find affordable one-way fares based on user searches. Data last updated July 3, 2025.

Wed 8/209:03 pmSAN - PTY

Nonstop6h 22mCopa Airlines

Deal found 7/1

$141

Wed 8/2010:30 pmSAN - PTY

1 stop12h 20mDelta

Deal found 7/1

$145

Sun 8/176:47 pmSAN - PTY

2 stops19h 25mUnited Airlines

Deal found 7/2

$151

Thu 9/188:16 amSAN - PTY

3 stops38h 29mMultiple Airlines

Deal found 7/2

$228

Cheapflights Fare Finder

Use the filters below to find and compare flights from San Diego to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Tue 8/26

6:15 am-6:37 pm

1 stop10h 22m

Panama City Tocumen Intl

Tue 9/9

3:35 pm-12:15 am

1 stop10h 40m

$339

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Fri 8/15

9:03 pm-5:25 am

Nonstop6h 22m

Panama City Tocumen Intl

Fri 8/29

1:15 pm-5:44 pm

Nonstop6h 29m

$341

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Sun 9/14

9:50 pm-12:55 pm

1 stop13h 05m

Panama City Tocumen Intl

Sat 9/27

2:10 pm-6:07 pm

1 stop29h 57m

$365

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Fri 8/1

7:30 pm-12:54 pm

2 stops15h 24m

Panama City Tocumen Intl

Sun 8/3

1:55 pm-8:56 am

2 stops21h 01m

$473

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Sun 8/17

9:03 pm-5:25 am

Nonstop6h 22m

Panama City Tocumen Intl

Sat 8/23

3:20 am-10:08 am

2 stops32h 48m

$522

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Wed 8/20

9:03 pm-5:25 am

Nonstop6h 22m

$141

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Wed 8/20

8:11 pm-6:37 pm

2 stops20h 26m

$145

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Thu 9/18

8:16 am-12:45 am

3 stops38h 29m

$228

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/1

Best time to book a flight from San Diego to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from San Diego with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Diego to Panama City

How far ahead should I book a flight from San Diego to Panama City?

The best time to book flights from San Diego to Panama City is 88 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from San Diego to Panama City?

Currently, October is the cheapest month in which you can book a flight from San Diego to Panama City (average of $478). Flying from San Diego to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SAN to PTY?

Unlike in the morning, when flights are generally more expensive, you can save up to 29% on flights from San Diego to Panama City by exploring options for tickets in the afternoon.

How much does it cost to fly round-trip from San Diego to Panama City?

Reviews of airlines servicing Panama City

Peruse reviews from past customers who have flown with Delta, Copa Airlines, and United Airlines from San Diego to Panama City to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,970 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Delta

8.0

Very good

7,970 reviews

Delta

8.0

Very good

7,970 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Copa Airlines

7.5

Good

1,467 reviews

Delta

8.0

Very good

7,970 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

United Airlines

7.4

Good

8,845 reviews

Delta

8.0

Very good

7,970 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

7,970 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

What are the cheapest airlines flying from San Diego to Panama City round-trip?
According to our current data, United Airlines ($339), Copa Airlines ($341), and Delta ($365) offers the cheapest pricing from San Diego to Panama City. United Airlines is currently priced 44% below the average price you’ll pay for this route.
What are the cheapest airlines to fly from San Diego to Panama City one-way?
The cheapest airline one-way is Copa Airlines, with whom users have recently found tickets for as low as $141. However, be on the lookout for offers from Delta and United Airlines, as they are both options that can get you from San Diego to Panama City for a low price.
What are the cheapest flights from San Diego to Panama City?
While on average a flight from San Diego to Panama City is generally $1,478, our data shows the cheapest flight currently is $172. When looking at the most popular route, (San Diego - Panama City Tocumen Intl), you can expect to pay $339 for that flight.
Can I find deals for flights from San Diego to Panama City that include hotel bookings?
Yes. In addition to deals on San Diego to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from San Diego to Panama City?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Diego to Panama City.
Can I find deals for business class flights from San Diego to Panama City?
Yes. Cheapflights offers flight deals from San Diego to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from San Diego to Panama City?
Currently, October is the cheapest month in which you can book a flight from San Diego to Panama City (average of $478). Flying from San Diego to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Alternative routes for San Diego to Panama City

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Top 4 airlines flying from San Diego to Panama City

Airline	Cheapest	Average	Flexibility	On-time
Copa Airlines	Cheapest$224	Average$410	FlexibilityNo cancel fee	On-time70%
Delta	Cheapest$355	Average$609	FlexibilityNo cancel fee	On-timeN/A
United Airlines	Cheapest$403	Average$653	FlexibilityNo cancel fee	On-time69%
American Airlines	Cheapest$596	Average$693	FlexibilityNo cancel fee	On-time71%

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$141+ Cheap flights from San Diego (SAN) to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/20. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from San Diego to Panama City with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheapflights Tip: The best prices from San Diego to Panama City Tocumen Intl are usually found in September or July, booked 88 days in advance, depart on a Wednesday or Friday and return on a Monday

Cheap flight deals from San Diego to Panama City

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Good round-trip deal

Good one-way deal

Find flight deals from San Diego to Panama City

Cheapest flights from San Diego to Panama CityExplore the most affordable flight options available from San Diego to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 3, 2025.

Explore the most affordable flight options available from San Diego to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 3, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from San Diego to Panama City that are best for you.

Best time to book a flight from San Diego to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from San Diego with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from San Diego to Panama City

How far ahead should I book a flight from San Diego to Panama City?

Use this chart to determine the optimal time to book a round-trip flight from San Diego to Panama City. Price data was last updated on June 27, 2025.

What is the cheapest month to book a flight from San Diego to Panama City?

What is the cheapest time of day to fly from SAN to PTY?

Find hourly flight availability from San Diego to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 3, 2025.

How much does it cost to fly round-trip from San Diego to Panama City?

Reviews of airlines servicing Panama City

Peruse reviews from past customers who have flown with Delta, Copa Airlines, and United Airlines from San Diego to Panama City to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from San Diego to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What are the cheapest airlines flying from San Diego to Panama City round-trip?

What are the cheapest airlines to fly from San Diego to Panama City one-way?

What are the cheapest flights from San Diego to Panama City?

Can I find deals for flights from San Diego to Panama City that include hotel bookings?

How can I find direct flights from San Diego to Panama City?

Can I find deals for business class flights from San Diego to Panama City?

What is the cheapest month to book a flight from San Diego to Panama City?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for San Diego to Panama City

See prices for flight routes from nearby airports that may be better suited for you.

Top 4 airlines flying from San Diego to Panama City

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Cheapest flights from San Diego to Panama City
Explore the most affordable flight options available from San Diego to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 3, 2025.