$281+ Cheap flights from Denver (DEN) to Panama City (PTY)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/4. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — PTY
Oct 21 — Oct 281
Round-trip
1 adult, Economy
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Find cheap flights from Denver to Panama City with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Denver Intl to Panama City Tocumen Intl are usually found in April or May, booked 89 days in advance, depart on a Tuesday or Wednesday and return on a Saturday
Cheap flight deals from Denver to Panama City
Cheapest
Best
Last-minute
One-way
Cheapest flights from Denver to Panama CityExplore the most affordable flight options available from Denver to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 21, 2026.
Explore the most affordable flight options available from Denver to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 21, 2026.
This Copa Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1710:43 pm -
Nonstop5h 50m
Sat 10/2412:56 pm -
Nonstop6h 15m
Deal found 9/16![Copa Airlines logo]()
$629
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/192:58 pm -
2 stops21h 36m
Tue 11/243:34 pm -
2 stops21h 51m
Deal found 9/16![American Airlines logo]()
$631
This Delta deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2512:50 am -
1 stop11h 08m
Fri 10/22:23 pm -
1 stop29h 42m
Deal found 9/18![Delta logo]()
$632
This American Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/511:59 pm -
1 stop12h 14m
Wed 11/113:13 pm -
1 stop9h 46m
Deal found 9/19![American Airlines logo]()
$636
This American Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/243:14 pm -
2 stops20h 48m
Fri 2/264:04 pm -
2 stops21h 33m
Deal found 9/19![American Airlines logo]()
$640
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/192:58 pm -
2 stops21h 36m
Fri 11/273:34 pm -
2 stops22h 07m
Deal found 9/17![American Airlines logo]()
$641
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/3111:53 pm -
1 stop13h 20m
Wed 11/43:13 pm -
1 stop9h 46m
Deal found 9/16![American Airlines logo]()
$644
This American Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/41:13 pm -
2 stops23h 00m
Wed 11/113:13 pm -
1 stop9h 46m
Deal found 9/19![American Airlines logo]()
$645
This American Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/2711:59 pm -
1 stop11h 17m
Sun 10/41:16 pm -
1 stop10h 47m
Deal found 9/20![American Airlines logo]()
$649
This Copa Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/310:43 pm -
Nonstop5h 50m
Sat 10/1012:56 pm -
Nonstop6h 15m
Deal found 9/19![Copa Airlines logo]()
$652
Best flights from Denver to Panama CityDiscover carefully curated flight deals from Denver to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 21, 2026.
Discover carefully curated flight deals from Denver to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 21, 2026.
This Copa Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1910:43 pm -
Nonstop5h 50m
Fri 10/2312:56 pm -
Nonstop6h 15m
Deal found 9/16![Copa Airlines logo]()
$629
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/265:00 pm -
1 stop18h 59m
Fri 10/302:24 pm -
1 stop9h 08m
Deal found 9/16![Delta logo]()
$644
This United Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/198:39 pm -
1 stop16h 06m
Mon 3/14:41 pm -
1 stop8h 46m
Deal found 9/21![United Airlines logo]()
$732
This Copa Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2410:43 pm -
Nonstop5h 50m
Fri 1/2912:56 pm -
Nonstop6h 16m
Deal found 9/19![Copa Airlines logo]()
$689
This Delta deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/65:00 pm -
1 stop18h 59m
Mon 11/163:29 pm -
1 stop9h 46m
Deal found 9/19![Delta logo]()
$729
This United Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/85:00 am -
1 stop7h 45m
Thu 1/2111:35 am -
1 stop13h 52m
Deal found 9/18![United Airlines logo]()
$742
This Copa Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2410:43 pm -
Nonstop5h 50m
Fri 2/2612:56 pm -
Nonstop6h 18m
Deal found 9/19![Copa Airlines logo]()
$689
This Delta deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/155:00 pm -
1 stop17h 15m
Sat 1/231:40 pm -
1 stop11h 39m
Deal found 9/20![Delta logo]()
$732
This Copa Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/149:49 pm -
Nonstop5h 44m
Wed 4/712:45 pm -
Nonstop6h 19m
Deal found 9/16![Copa Airlines logo]()
$727
This Delta deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/153:35 pm -
1 stop18h 40m
Fri 1/223:20 pm -
1 stop9h 59m
Deal found 9/18![Delta logo]()
$732
This Copa Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/309:50 pm -
Nonstop5h 43m
Mon 12/712:56 pm -
Nonstop6h 14m
Deal found 9/19![Copa Airlines logo]()
$727
This Delta deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/85:00 pm -
1 stop18h 55m
Sat 1/161:40 pm -
1 stop21h 55m
Deal found 9/20![Delta logo]()
$746
Last-minute flights from Denver to Panama CityDiscover last-minute flight deals from Denver to Panama City. Data last updated September 21, 2026 and is based on user searches.
Discover last-minute flight deals from Denver to Panama City. Data last updated September 21, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2512:50 am -
1 stop11h 08m
Fri 10/22:23 pm -
1 stop29h 42m
Deal found 9/18![Delta logo]()
$632
This American Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/2711:59 pm -
1 stop11h 17m
Sun 10/41:16 pm -
1 stop10h 47m
Deal found 9/20![American Airlines logo]()
$649
This Copa Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/310:43 pm -
Nonstop5h 50m
Sat 10/1012:56 pm -
Nonstop6h 15m
Deal found 9/19![Copa Airlines logo]()
$652
This oojo deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/510:43 pm -
Nonstop5h 50m
Thu 10/2212:56 pm -
Nonstop6h 15m
Deal found 9/18![Copa Airlines logo]()
$679
This Copa Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1710:43 pm -
Nonstop5h 50m
Sat 10/2412:56 pm -
Nonstop6h 15m
Deal found 9/16![Copa Airlines logo]()
$629
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1811:53 pm -
1 stop12h 09m
Sat 10/242:02 pm -
1 stop22h 20m
Deal found 9/16![American Airlines logo]()
$660
This American Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2411:53 pm -
1 stop12h 09m
Fri 2/262:39 pm -
1 stop11h 20m
Deal found 9/19![American Airlines logo]()
$636
This American Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2411:53 pm -
1 stop12h 09m
Fri 1/294:55 pm -
2 stops18h 43m
Deal found 9/19![American Airlines logo]()
$640
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/3111:53 pm -
1 stop13h 20m
Wed 11/43:13 pm -
1 stop9h 46m
Deal found 9/16![American Airlines logo]()
$644
One-way flights from Denver to Panama CitySearch for one-way flight options from Denver to Panama City. Find affordable one-way fares based on user searches. Data last updated September 21, 2026.
Search for one-way flight options from Denver to Panama City. Find affordable one-way fares based on user searches. Data last updated September 21, 2026.
This American Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/412:52 am -
2 stops12h 41m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![American Airlines logo]()
$281
This American Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/2011:59 pm -
1 stop13h 56m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![American Airlines logo]()
$296
This FlightHub deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/203:15 pm -
2 stops18h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Multiple Airlines logo]()
$297
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/512:36 pm -
1 stop23h 37m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![American Airlines logo]()
$302
This Priceline deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/193:15 pm -
2 stops18h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![Multiple Airlines logo]()
$307
This FlightHub deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/2212:50 pm -
2 stops35h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![Multiple Airlines logo]()
$310
This FlightHub deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/243:15 pm -
2 stops33h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Multiple Airlines logo]()
$314
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/73:08 pm -
2 stops21h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![American Airlines logo]()
$315
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/62:59 pm -
2 stops21h 14m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![American Airlines logo]()
$320
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/71:10 pm -
1 stop18h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Multiple Airlines logo]()
$326
Find flight deals from Denver to Panama City
Discover tips and strategies to find the most affordable flight options for your journey from Denver (DEN) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 21, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $627 (American Airlines) |
One-way from | $281 (American Airlines) |
Popular in | December |
Cheapest in | April |
Average price | $651 |
Good round-trip deal | $627 or less |
Good one-way deal | $313 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Denver to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 21, 2026.
Use the filters below to find and compare flights from Denver to Panama City that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
DenverPanama City
DEN Denver Intl - PTY Panama City Tocumen Intl
DENPTY
Denver Intl
Thu 11/5
12:36 pm-2:13 pm
1 stop23h 37m
Panama City Tocumen Intl
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$302
DenverPanama City
DEN Denver Intl - PTY Panama City Tocumen Intl
DENPTY
Denver Intl
Sat 10/24
3:15 pm-2:10 am
2 stops33h 55m
Panama City Tocumen Intl
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$314
DenverPanama City
DEN Denver Intl - PTY Panama City Tocumen Intl
DENPTY
Denver Intl
Sat 3/13
11:31 pm-12:40 pm
1 stop11h 09m
Panama City Tocumen Intl
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$425
DenverPanama City
DEN Denver Intl - PTY Panama City Tocumen Intl
DENPTY
Denver Intl
Thu 10/8
12:15 pm-1:02 pm
1 stop23h 47m
Panama City Tocumen Intl
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$505
DenverPanama City
DEN Denver Intl - PTY Panama City Tocumen Intl
DENPTY
Denver Intl
Thu 12/31
8:05 am-1:33 pm
3 stops27h 28m
Panama City Tocumen Intl
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$521
DenverPanama City
DEN Denver Intl - PTY Panama City Tocumen Intl
DENPTY
Denver Intl
Fri 12/25
3:24 pm-1:33 pm
1 stop20h 09m
Panama City Tocumen Intl
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$611
DenverPanama City
DEN Denver Intl - PTY Panama City Tocumen Intl
DENPTY
Denver Intl
Mon 10/19
10:43 pm-5:33 am
Nonstop5h 50m
Panama City Tocumen Intl
Fri 10/23
12:56 pm-6:11 pm
Nonstop6h 15m
$629
DenverPanama City
DEN Denver Intl - PTY Panama City Tocumen Intl
DENPTY
Denver Intl
Thu 10/8
9:44 am-1:55 pm
3 stops27h 11m
Panama City Tocumen Intl
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$639
DenverPanama City
DEN Denver Intl - PTY Panama City Tocumen Intl
DENPTY
Denver Intl
Mon 10/26
5:00 pm-12:59 pm
1 stop18h 59m
Panama City Tocumen Intl
Fri 10/30
2:24 pm-10:32 pm
1 stop9h 08m
$644
DenverPanama City
DEN Denver Intl - PTY Panama City Tocumen Intl
DENPTY
Denver Intl
Sat 10/24
10:43 pm-5:33 am
Nonstop5h 50m
Panama City Tocumen Intl
Fri 1/29
12:56 pm-5:12 pm
Nonstop6h 16m
$689
Showing 1-10 of 24 resultsSorted by cheapest first
Compare providers for flights from Denver to Panama City
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Denver to Panama City in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star |
- Most accurate provider: When it comes to deals on Denver-Panama City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Denver-Panama City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Denver-Panama City flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Denver-Panama City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Denver-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Denver to Panama City
Have a flexible travel schedule? Discover the best time to fly to Panama City from Denver with our price prediction graph.
DEN-PTY
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Denver to Panama City
How far ahead should I book a flight from Denver to Panama City?
The price you pay for your flight from Denver to Panama City may vary depending on when you book. For the best chance of a lower fare, look to book 88 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Denver to Panama City?
Currently, April is the cheapest month in which you can book a flight from Denver to Panama City (average of $589). Flying from Denver to Panama City in December is currently the most expensive (average of $858). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from DEN to PTY?
Find hourly flight availability from Denver to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 21, 2026.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Denver to Panama City as you normally would.
The best insider tips for Denver to Panama City flights
AI-powered summary based on content written by travel experts. AI can make mistakes.
Cheapflights partnered with top experts to bring you the best recommendations for your Denver to Panama City trip
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Reviews of airlines servicing Panama City
Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated September 21, 2026.
Get a feel of what it's like to fly with Copa Airlines,United Airlines, andAmerican Airlines from Denver to Panama City by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.6
Comfort
7.4
Boarding
7.8
Entertainment
6.9
Crew
8.1
Food
6.9
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Overall
7.6
Comfort
7.4
Boarding
7.8
Entertainment
6.9
Crew
8.1
Food
6.9
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Overall
7.6
Comfort
7.4
Boarding
7.8
Entertainment
6.9
Crew
8.1
Food
6.9
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Overall
7.6
Comfort
7.4
Boarding
7.8
Entertainment
6.9
Crew
8.1
Food
6.9
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Related info for your journey
Find useful and relevant information for your journey from Denver to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Denver to Panama City
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Complete your trip
Complete your trip to Panama City by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Denver to Panama City by cabin class
Find flights from Denver to Panama City, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Denver and Panama City flights
Browse other Denver and Panama City flight options. Last updated on September 21, 2026.
Other flights from Denver
Browse through other flights departing from Denver. Flights are based on user searches made on Cheapflights and were last updated on September 21, 2026.
Other flights to Panama City
Explore flights to Panama City departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 21, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from Denver to Panama City
Discover the top 3 airlines that operate flights from Denver to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 21, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$493 | Average$653 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$549 | Average$695 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$554 | Average$674 | FlexibilityNo cancel fee | On-time71% |