How popular is this Denver to Panama City flight route?

Flights from Denver Intl to Panama City Tocumen Intl have been viewed 40 times in the past calendar month.

What are the cheapest airlines flying from Denver to Panama City round-trip?

Currently priced at $509, Copa Airlines will fly you from Denver to Panama City and back. In addition to Copa Airlines, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from United Airlines and American Airlines - these airlines can fly you to your destination from $527 and $528, respectively. You may be able to fly from Denver to Panama City for 18% less than the average price by searching for these airlines.

What is the cheapest day to fly from Denver to Panama City?

Travelers seeking maximum savings on their Denver to Panama City flight should consider departing on Tuesday evenings when fares are most often at their lowest. Monday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

In terms of precipitation, rainfall in Panama City ranges from 0.4 - 13.4 inches per month. October is typically the wettest month, when rainfall can reach 13.4 in. February is typically the driest time to visit Panama City when rainfall is around 0.4 in.

If weather is an important factor for your trip to Panama City, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 78.8 F).

What are the cheapest flights from Denver to Panama City?

On average you can expect to pay $1,266 for a flight from Denver to Panama City. The cheapest flight overall is $172 while the most popular route, (Denver Intl - Panama City Tocumen Intl) is currently priced at $513.

What are the most popular airlines that fly from Denver to Panama City?

Before booking your flight from Denver to Panama City check out the most popular airlines for this route: American Airlines, Copa Airlines or Delta.

What is the cheapest day to fly round-trip from Denver to Panama City?

Users have found that flying from Denver to Panama City on a Friday typically leans towards higher prices. However, this doesn’t mean you still can’t find a deal. Flexibility with other aspects of your flight can still land a great price for your trip.

How far in advance should I book a flight from Denver to Panama City?

Find a great deal and save up to 55% by booking at least 34 days prior to your desired departure date, rather than waiting until the week of travel. According to our data, there are a number of flights available from Denver to Panama City within the next two weeks, with the cheapest ticket starting at $503.

What is the cheapest month to fly from Denver to Panama City?

The best pricing can be found in the month of October. Prices to Panama City from Denver average $622. You can even find prices in October for less than $622, as users have found deals to Panama City from as low as $472. The month of December appears to be one of the more expensive times to travel to Panama City from Denver. Flying in the targeted month can save you up to 29%.

What airports do I use to fly from Denver to Panama City?

Panama City Tocumen Intl is the airport most travelers will use when flying to Panama City from Denver Intl. Booking flights from Denver Intl (DEN) to Tocumen Intl (PTY) should be relatively easy as there is 1 daily flight to Panama City from 4 different airlines. 5h 46m is how long a flight from Denver to Panama City Tocumen Intl will take if you book a nonstop flight.

Can I find deals for flights from Denver to Panama City that include hotel bookings?

Yes. In addition to deals on Denver to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Denver to Panama City?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Denver to Panama City.

Can I find deals for business class flights from Denver to Panama City?

Yes. Cheapflights offers flight deals from Denver to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$167+ Flights from Denver to Panama City

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Cheapflights Tip: The best prices from Denver Intl to Panama City Tocumen Intl are usually found in October or July, booked 33 days in advance, depart on a Tuesday or Monday and return on a Thursday

Cheap flight deals from Denver to Panama City

Round-trip from	$431 (Kiwi.com)
One-way from	$167 (Kiwi.com)
Popular in	December
Cheapest in	October
Average price	$527
Good round-trip deal	$540 or less
Good one-way deal	$191 or less

From Denver Intl to Panama City Tocumen Intl

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One-way flight from Denver Intl to Panama City Tocumen Intl

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Highest demand for flights based on searches. 8% potential increase in price ($57 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 2% potential price decrease ($17 potential savings vs. average RT price).

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Average for round-trip flights in July 2025

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Price to beat on a round-trip flight from Denver Intl to Panama City Tocumen Intl.

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Price to beat on a one-way flight from Denver Intl to Panama City Tocumen Intl.

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Find flight deals from Denver to Panama City

Cheapest flights from Denver to Panama City
Explore the most affordable flight options available from Denver to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 2, 2025.

Mon 8/1112:34 amDEN - PTY

1 stop9h 06mMultiple Airlines

Wed 8/209:33 pmPTY - DEN

1 stop11h 48mMultiple Airlines

Deal found 7/1

$431

Wed 8/1310:47 pmDEN - PTY

Nonstop5h 46mCopa Airlines

Mon 8/1812:56 pmPTY - DEN

Nonstop6h 07mCopa Airlines

Deal found 6/30

$509

Thu 8/77:45 amDEN - PTY

1 stop9h 52mUnited Airlines

Thu 8/143:30 pmPTY - DEN

1 stop9h 08mUnited Airlines

Deal found 7/2

$527

Wed 8/1311:52 pmDEN - PTY

1 stop13h 38mAmerican Airlines

Mon 8/183:30 pmPTY - DEN

1 stop21h 38mAmerican Airlines

Deal found 6/30

$528

Thu 10/2312:59 amDEN - PTY

1 stop10h 48mDelta

Tue 11/43:12 pmPTY - DEN

1 stop9h 03mDelta

Deal found 6/30

$617

Best flights from Denver to Panama City
Discover carefully curated flight deals from Denver to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 2, 2025.

Mon 8/1112:34 amDEN - PTY

1 stop9h 06mMultiple Airlines

Wed 8/209:33 pmPTY - DEN

1 stop11h 48mMultiple Airlines

Deal found 7/1

$431

Wed 8/1310:47 pmDEN - PTY

Nonstop5h 46mCopa Airlines

Mon 8/1812:56 pmPTY - DEN

Nonstop6h 07mCopa Airlines

Deal found 6/30

$509

Thu 8/75:30 amDEN - PTY

1 stop13h 40mUnited Airlines

Sun 8/103:35 pmPTY - DEN

1 stop19h 35mUnited Airlines

Deal found 7/2

$527

Wed 8/1311:52 pmDEN - PTY

1 stop13h 38mAmerican Airlines

Mon 8/183:30 pmPTY - DEN

1 stop21h 38mAmerican Airlines

Deal found 6/30

$528

Sun 7/2712:59 amDEN - PTY

1 stop11h 14mDelta

Mon 8/42:28 pmPTY - DEN

1 stop10h 52mDelta

Deal found 6/30

$655

Last-minute flights from Denver to Panama City
Discover last-minute flight deals from Denver to Panama City. Data last updated July 2, 2025 and is based on user searches.

Fri 7/1112:34 amDEN - PTY

1 stop14h 52mMultiple Airlines

Tue 7/159:33 pmPTY - DEN

1 stop11h 48mMultiple Airlines

Deal found 6/30

$580

Fri 7/117:45 amDEN - PTY

1 stop7h 27mUnited Airlines

Mon 8/43:30 pmPTY - DEN

1 stop9h 08mUnited Airlines

Deal found 6/30

$707

Fri 7/113:53 pmDEN - PTY

2 stops20h 01mAmerican Airlines

Mon 8/43:10 pmPTY - DEN

2 stops19h 26mAmerican Airlines

Deal found 6/30

$712

Fri 7/1110:42 pmDEN - PTY

Nonstop5h 51mCopa Airlines

Mon 8/412:56 pmPTY - DEN

Nonstop6h 07mCopa Airlines

Deal found 6/30

$873

Sun 7/2712:59 amDEN - PTY

1 stop11h 14mDelta

Mon 8/42:28 pmPTY - DEN

1 stop10h 52mDelta

Deal found 6/30

$655

Thu 8/77:45 amDEN - PTY

1 stop9h 52mUnited Airlines

Thu 8/143:30 pmPTY - DEN

1 stop9h 08mUnited Airlines

Deal found 7/2

$527

Mon 8/1112:34 amDEN - PTY

1 stop9h 06mMultiple Airlines

Wed 8/209:33 pmPTY - DEN

1 stop11h 48mMultiple Airlines

Deal found 7/1

$431

Wed 8/1310:47 pmDEN - PTY

Nonstop5h 46mCopa Airlines

Mon 8/1812:56 pmPTY - DEN

Nonstop6h 07mCopa Airlines

Deal found 6/30

$509

Wed 8/1311:52 pmDEN - PTY

1 stop13h 38mAmerican Airlines

Mon 8/183:30 pmPTY - DEN

1 stop21h 38mAmerican Airlines

Deal found 6/30

$528

One-way flights from Denver to Panama City
Search for one-way flight options from Denver to Panama City. Find affordable one-way fares based on user searches. Data last updated July 2, 2025.

Mon 8/412:34 amDEN - PTY

2 stops35h 01mMultiple Airlines

Deal found 7/2

$167

Cheapflights Fare Finder

Use the filters below to find and compare flights from Denver to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Mon 8/11

12:34 am-10:40 am

1 stop9h 06m

Panama City Tocumen Intl

Wed 8/20

9:33 pm-8:21 am

1 stop11h 48m

$431

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Wed 8/13

10:47 pm-5:33 am

Nonstop5h 46m

Panama City Tocumen Intl

Mon 8/18

12:56 pm-6:03 pm

Nonstop6h 07m

$509

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Thu 8/7

7:45 am-6:37 pm

1 stop9h 52m

Panama City Tocumen Intl

Thu 8/14

3:30 pm-11:38 pm

1 stop9h 08m

$527

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Wed 8/13

11:52 pm-2:30 pm

1 stop13h 38m

Panama City Tocumen Intl

Mon 8/18

3:30 pm-12:08 pm

1 stop21h 38m

$528

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Thu 10/23

12:59 am-12:47 pm

1 stop10h 48m

Panama City Tocumen Intl

Tue 11/4

3:12 pm-10:15 pm

1 stop9h 03m

$617

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Mon 8/4

12:34 am-12:35 pm

2 stops35h 01m

$167

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/2

The best insider tips for Denver to Panama City flights

Cheapflights partnered with top experts to bring you the best recommendations for your Denver to Panama City trip

Airports

DEN

Use the A Line train for a quick 37-minute ride from Denver Union Station to DEN, avoiding traffic and parking hassles.

PTY

For a quick city transfer, Uber is typically faster and cheaper than taxis from PTY to Panama City.

Our travel experts

Taryn White

Expert on PTY

Emily Zemler

Expert on DEN

Best time to book a flight from Denver to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Denver with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Denver to Panama City

How far ahead should I book a flight from Denver to Panama City?

The price you pay for your flight from Denver to Panama City may vary depending on when you book. For the best chance of a lower fare, look to book 33 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Denver to Panama City?

Currently, October is the cheapest month in which you can book a flight from Denver to Panama City (average of $478). Flying from Denver to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DEN to PTY?

One of the essential ways to save on airfare from Denver to Panama City is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight at noon could potentially save you up to 21% on airfare.

Reviews of airlines servicing Panama City

Get a feel of what it's like to fly with Delta, Copa Airlines, and United Airlines from Denver to Panama City by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,983 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Delta

8.0

Very good

7,983 reviews

Delta

8.0

Very good

7,983 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Copa Airlines

7.5

Good

1,465 reviews

Delta

8.0

Very good

7,983 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

United Airlines

7.4

Good

8,861 reviews

Delta

8.0

Very good

7,983 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

7,983 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

What airports do I use to fly from Denver to Panama City?
Panama City Tocumen Intl is the airport most travelers will use when flying to Panama City from Denver Intl. Booking flights from Denver Intl (DEN) to Tocumen Intl (PTY) should be relatively easy as there is 1 daily flight to Panama City from 4 different airlines. 5h 46m is how long a flight from Denver to Panama City Tocumen Intl will take if you book a nonstop flight.
How popular is this Denver to Panama City flight route?
Flights from Denver Intl to Panama City Tocumen Intl have been viewed 40 times in the past calendar month.
What are the cheapest airlines flying from Denver to Panama City round-trip?
Currently priced at $509, Copa Airlines will fly you from Denver to Panama City and back. In addition to Copa Airlines, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from United Airlines and American Airlines - these airlines can fly you to your destination from $527 and $528, respectively. You may be able to fly from Denver to Panama City for 18% less than the average price by searching for these airlines.
What are the cheapest flights from Denver to Panama City?
On average you can expect to pay $1,266 for a flight from Denver to Panama City. The cheapest flight overall is $172 while the most popular route, (Denver Intl - Panama City Tocumen Intl) is currently priced at $513.
Can I find deals for flights from Denver to Panama City that include hotel bookings?
Yes. In addition to deals on Denver to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Denver to Panama City?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Denver to Panama City.
Can I find deals for business class flights from Denver to Panama City?
Yes. Cheapflights offers flight deals from Denver to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Denver to Panama City?
Currently, October is the cheapest month in which you can book a flight from Denver to Panama City (average of $478). Flying from Denver to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top 4 airlines flying from Denver to Panama City

Airline	Cheapest	Average	Flexibility	On-time
Copa Airlines	Cheapest$477	Average$622	FlexibilityNo cancel fee	On-time70%
Delta	Cheapest$491	Average$755	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$491	Average$642	FlexibilityNo cancel fee	On-time71%
United Airlines	Cheapest$526	Average$702	FlexibilityNo cancel fee	On-time69%

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$167+ Cheap flights from Denver (DEN) to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/4. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Denver to Panama City with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheapflights Tip: The best prices from Denver Intl to Panama City Tocumen Intl are usually found in October or July, booked 33 days in advance, depart on a Tuesday or Monday and return on a Thursday

Cheap flight deals from Denver to Panama City

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Good round-trip deal

Good one-way deal

Find flight deals from Denver to Panama City

Cheapest flights from Denver to Panama CityExplore the most affordable flight options available from Denver to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 2, 2025.

Explore the most affordable flight options available from Denver to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 2, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Denver to Panama City that are best for you.

The best insider tips for Denver to Panama City flights

Cheapflights partnered with top experts to bring you the best recommendations for your Denver to Panama City trip

Airports

DEN

PTY

Our travel experts

Best time to book a flight from Denver to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Denver with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Denver to Panama City

How far ahead should I book a flight from Denver to Panama City?

Use this chart to determine the optimal time to book a round-trip flight from Denver to Panama City. Price data was last updated on June 27, 2025.

What is the cheapest month to book a flight from Denver to Panama City?

What is the cheapest time of day to fly from DEN to PTY?

Find hourly flight availability from Denver to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 2, 2025.

Reviews of airlines servicing Panama City

Get a feel of what it's like to fly with Delta, Copa Airlines, and United Airlines from Denver to Panama City by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Denver to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airports do I use to fly from Denver to Panama City?

How popular is this Denver to Panama City flight route?

What are the cheapest airlines flying from Denver to Panama City round-trip?

What are the cheapest flights from Denver to Panama City?

Can I find deals for flights from Denver to Panama City that include hotel bookings?

How can I find direct flights from Denver to Panama City?

Can I find deals for business class flights from Denver to Panama City?

What is the cheapest month to book a flight from Denver to Panama City?

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Denver to Panama City

See prices for flight routes from nearby airports that may be better suited for you.

Top 4 airlines flying from Denver to Panama City

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Cheapest flights from Denver to Panama City
Explore the most affordable flight options available from Denver to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 2, 2025.