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Panama City

$209+ Cheap flights from Denver (DEN) to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/21. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — PTY
Jan 11 — Jan 181
Sun 1/11
Sun 1/18
1 adult, Economy
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Cheapflights Tip: The best prices from Denver Intl to Panama City Tocumen Intl are usually found in August or May, booked 36 days in advance, depart on a Tuesday or Thursday and return on a Tuesday

Cheap flight deals from Denver to Panama City

Cheapest flights from Denver to Panama City
Explore the most affordable flight options available from Denver to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

This United Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/195:00 amDEN - PTY
1 stop7h 45mUnited Airlines
Mon 1/194:41 pmPTY - DEN
1 stop9h 00mUnited Airlines
Deal found 12/11$671
This United Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2510:02 amDEN - PTY
1 stop7h 36mUnited Airlines
Wed 12/318:55 amPTY - DEN
1 stop16h 49mUnited Airlines
Deal found 12/10$678
This United Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/226:53 pmDEN - PTY
1 stop17h 52mUnited Airlines
Sun 12/284:41 pmPTY - DEN
1 stop17h 37mUnited Airlines
Deal found 12/10$728
This American Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/2911:38 pmDEN - PTY
1 stop14h 16mAmerican Airlines
Sat 1/102:27 pmPTY - DEN
1 stop11h 27mAmerican Airlines
Deal found 12/11$756
This American Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/293:59 pmDEN - PTY
2 stops19h 54mAmerican Airlines
Thu 1/82:27 pmPTY - DEN
2 stops22h 21mAmerican Airlines
Deal found 12/11$760
This Copa Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/299:36 pmDEN - PTY
Nonstop5h 57mCopa Airlines
Thu 1/812:56 pmPTY - DEN
Nonstop6h 20mCopa Airlines
Deal found 12/10$780
This United Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/175:02 amDEN - PTY
1 stop12h 36mUnited Airlines
Tue 12/238:55 amPTY - DEN
1 stop11h 24mUnited Airlines
Deal found 12/11$784
This United Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/305:00 amDEN - PTY
1 stop7h 45mUnited Airlines
Fri 1/94:41 pmPTY - DEN
1 stop18h 14mUnited Airlines
Deal found 12/10$788
This Copa Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/299:36 pmDEN - PTY
Nonstop5h 57mCopa Airlines
Sat 1/1012:56 pmPTY - DEN
Nonstop6h 20mCopa Airlines
Deal found 12/10$789
This United Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/195:00 amDEN - PTY
1 stop10h 07mUnited Airlines
Tue 12/304:41 pmPTY - DEN
1 stop17h 37mUnited Airlines
Deal found 12/10$790
This Copa Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/159:36 pmDEN - PTY
Nonstop5h 57mCopa Airlines
Wed 12/1712:56 pmPTY - DEN
Nonstop6h 21mCopa Airlines
Deal found 12/11$801

Find flight deals from Denver to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Denver (DEN) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 12, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$548
(Copa Airlines)

One-way from

$209
(Kiwi.com)

Popular in

March

Cheapest in

August

Average price

$739

Good round-trip deal

$447 or less

Good one-way deal

$198 or less
Provider with most accurate pricing for Denver Intl-Panama City Tocumen Intl flight deals.
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Provider most trusted by Cheapflights users for Denver Intl-Panama City Tocumen Intl flights.
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From Denver Intl to Panama City Tocumen Intl
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One-way flight from Denver Intl to Panama City Tocumen Intl
Search Deals
Highest demand for flights based on searches. 4% potential increase in price ($30 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($9 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals
Price to beat on a round-trip flight from Denver Intl to Panama City Tocumen Intl.
Search Deals
Price to beat on a one-way flight from Denver Intl to Panama City Tocumen Intl.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Denver to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
Use the filters below to find and compare flights from Denver to Panama City that are best for you.

Fly from

Denver

Fly to

Panama City

Route

Depart

Return

Price

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Sat 3/7

9:48 pm-5:33 am

Nonstop5h 45m

Panama City Tocumen Intl

Sat 3/14

12:56 pm-6:16 pm

Nonstop6h 20m

$548

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Mon 2/9

9:38 pm-5:33 am

Nonstop5h 55m

Panama City Tocumen Intl

Thu 2/19

12:56 pm-5:16 pm

Nonstop6h 20m

$548

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Fri 2/20

10:19 pm-6:10 am

Nonstop5h 51m

Panama City Tocumen Intl

Sat 2/28

12:56 pm-5:16 pm

Nonstop6h 20m

$548

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Fri 2/20

10:19 pm-6:10 am

Nonstop5h 51m

Panama City Tocumen Intl

Tue 2/24

12:56 pm-5:16 pm

Nonstop6h 20m

$548

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Wed 3/18

9:06 pm-4:07 pm

1 stop18h 01m

Panama City Tocumen Intl

Sun 3/29

3:30 pm-8:43 am

1 stop18h 13m

$550

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Thu 4/9

7:45 am-4:12 pm

1 stop7h 27m

Panama City Tocumen Intl

Sun 4/19

7:55 am-8:13 pm

1 stop13h 18m

$550

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Wed 3/18

9:06 pm-1:45 pm

1 stop15h 39m

Panama City Tocumen Intl

Fri 3/20

3:41 pm-6:40 am

1 stop15h 59m

$550

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Thu 3/26

5:00 am-4:07 pm

1 stop10h 07m

Panama City Tocumen Intl

Mon 4/6

7:55 am-8:13 pm

1 stop13h 18m

$550

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Fri 5/1

10:51 pm-5:33 am

Nonstop5h 42m

Panama City Tocumen Intl

Wed 5/6

12:56 pm-6:25 pm

Nonstop6h 29m

$550

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Sun 4/12

7:45 am-6:37 pm

1 stop9h 52m

Panama City Tocumen Intl

Sat 4/18

7:55 am-8:13 pm

1 stop13h 18m

$550

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/11

Showing 1-10 of 20 results
1
2

Compare providers for flights from Denver to Panama City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Denver to Panama City in December.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
AranGrantPrice Accuracy2 starsTrust Score*3 stars
CheapTicketsDealPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Denver-Panama City flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Denver-Panama City flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Denver-Panama City flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Denver-Panama City flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Denver-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Denver to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Denver with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Denver to Panama City

How far ahead should I book a flight from Denver to Panama City?

Use this chart to determine the optimal time to book a round-trip flight from Denver to Panama City. Price data was last updated on December 5, 2025.

The price you pay for your flight from Denver to Panama City may vary depending on when you book. For the best chance of a lower fare, look to book 36 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Denver to Panama City?

Currently, March is the cheapest month in which you can book a flight from Denver to Panama City (average of $354). Flying from Denver to Panama City in January is currently the most expensive (average of $534). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DEN to PTY?

Find hourly flight availability from Denver to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 12, 2025.

One of the essential ways to save on airfare from Denver to Panama City is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight at noon could potentially save you up to 47% on airfare.

The best insider tips for Denver to Panama City flights

AI-powered summary based on content written by travel experts. AI can make mistakes.
Cheapflights partnered with top experts to bring you the best recommendations for your Denver to Panama City trip
Airports
DEN

Use the A Line train for a quick 37-minute ride from Denver Union Station to DEN, avoiding traffic and parking hassles.

Read more about DENBy Emily Zemler
PTY

For a quick city transfer, Uber is typically faster and cheaper than taxis from PTY to Panama City.

Read more about PTYBy Taryn White
Our travel experts
Taryn White

Taryn White

Expert on PTY

Taryn White

Taryn White

Taryn White is a freelance travel writer, digital creator, and travel advisor who has visited nearly 100 countries and all 50 states. She’s familiar with many airports and enjoys beach hopping, boutique hotels, spa experiences, and exploring local culture. Her work has appeared in Travel + Leisure, Condé Nast Traveler, National Geographic, Smithsonian Magazine, AFAR, and more.

Read more
Emily Zemler

Emily Zemler

Expert on DEN

Emily Zemler

Emily Zemler

Emily is a freelance writer and book author based in London covering entertainment and travel. Her work has appeared in Los Angeles Times, Observer, and Conde Nast Traveler She has ventured to more than 40 countries and all seven continents, always in search of a great art museum. She has written extensively about hotels, luxury travel, and aviation.

Read more

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated December 12, 2025.
Get a feel of what it's like to fly with Delta, Copa Airlines, and United Airlines from Denver to Panama City by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,005 reviews

Overall

7.9

Boarding

8.1

Comfort

7.9

Entertainment

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,005 reviews
Delta
7.9
Good
8,005 reviews

Overall

7.9

Boarding

8.1

Comfort

7.9

Entertainment

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Copa Airlines
7.6
Good
1,558 reviews
Delta
7.9
Good
8,005 reviews

Overall

7.9

Boarding

8.1

Comfort

7.9

Entertainment

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,095 reviews
Delta
7.9
Good
8,005 reviews

Overall

7.9

Boarding

8.1

Comfort

7.9

Entertainment

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,050 reviews
Delta
7.9
Good
8,005 reviews

Overall

7.9

Boarding

8.1

Comfort

7.9

Entertainment

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Denver to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Denver to Panama City?

    Panama City Tocumen Intl is the airport most travelers will use when flying to Panama City from Denver Intl. Booking flights from Denver Intl (DEN) to Tocumen Intl (PTY) should be relatively easy as there are 2 daily flights to Panama City from 4 different airlines. 5h 42m is how long a flight from Denver to Panama City Tocumen Intl will take if you book a nonstop flight.

  • How popular is this Denver to Panama City flight route?

    Flights from Denver Intl to Panama City Tocumen Intl have been viewed 38 times in the past calendar month.

  • How long is the flight from Denver to Panama City?

    Airlines like Copa Airlines and United Airlines fly from Denver to Panama City in about 5h 45m. The time it takes to get you to your destination can typically vary by up to 12h 16m. Denver and Panama City are separated by a distance of 2634 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Denver to Panama City round-trip?

    Currently priced at $463, Copa Airlines will fly you from Denver to Panama City and back. In addition to Copa Airlines, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from American Airlines and Delta - these airlines can fly you to your destination from $527 and $527, respectively. You may be able to fly from Denver to Panama City for 28% less than the average price by searching for these airlines.

  • What are the cheapest flights from Denver to Panama City?

    On average you can expect to pay $426 for a flight from Denver to Panama City. The cheapest flight overall is $154 while the most popular route, (Denver Intl - Panama City Tocumen Intl) is currently priced at $535.

  • Can I find deals for flights from Denver to Panama City that include hotel bookings?

    Yes. In addition to deals on Denver to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Denver to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Denver to Panama City.

  • Can I find deals for business class flights from Denver to Panama City?

    Yes. Cheapflights offers flight deals from Denver to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Denver to Panama City?

    Currently, March is the cheapest month in which you can book a flight from Denver to Panama City (average of $354). Flying from Denver to Panama City in January is currently the most expensive (average of $534). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Denver to Panama City

See prices for flight routes from nearby airports that may be better suited for you.
Colorado Springs to Panama City flights

Top 4 airlines flying from Denver to Panama City

Discover the top 4 airlines that operate flights from Denver to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$477Average$647FlexibilityNo cancel feeOn-time70%
DeltaCheapest$527Average$947FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$527Average$650FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$527Average$686FlexibilityNo cancel feeOn-time69%

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