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$125+ Cheap flights from Panama City (PTY) to Cali (CLO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/6. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — CLO
May 28 — Jun 41
Thu 5/28
Thu 6/4
1 adult, Economy
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Cheapflights Tip: The best prices from Panama City Tocumen Intl to Cali Alfonso B. Aragon Intl are usually found in February or April, booked 49 days in advance, depart on a Saturday or Friday and return on a Thursday

Cheap flight deals from Panama City to Cali

Cheapest flights from Panama City to Cali
Explore the most affordable flight options available from Panama City to Cali. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 28, 2026.

This Copa Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2712:29 pm
PTY
-
CLO
Nonstop1h 41m
Copa Airlines
Wed 4/2912:06 pm
CLO
-
PTY
Nonstop1h 34m
Copa Airlines
Deal found 4/23$268
This Copa Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/13:55 pm
PTY
-
CLO
Nonstop1h 41m
Copa Airlines
Fri 5/812:06 pm
CLO
-
PTY
Nonstop1h 34m
Copa Airlines
Deal found 4/28$269
This Avianca deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/13:10 pm
PTY
-
CLO
1 stop4h 50m
Avianca
Sat 5/97:50 pm
CLO
-
PTY
1 stop4h 45m
Avianca
Deal found 4/27$274
This Avianca deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/13:10 pm
PTY
-
CLO
1 stop3h 50m
Avianca
Mon 5/410:15 am
CLO
-
PTY
1 stop4h 00m
Avianca
Deal found 4/28$285
This Kiwi.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/304:25 am
PTY
-
CLO
1 stop5h 05m
Avianca
Sun 5/39:45 am
CLO
-
PTY
1 stop4h 30m
Avianca
Deal found 4/24$286
This FlightHub deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/223:10 pm
PTY
-
CLO
1 stop3h 50m
Avianca
Mon 5/2512:50 pm
CLO
-
PTY
1 stop4h 10m
Avianca
Deal found 4/27$291
This Trip.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/34:25 am
PTY
-
CLO
1 stop5h 55m
Avianca
Fri 5/89:55 pm
CLO
-
PTY
1 stop19h 05m
Avianca
Deal found 4/23$295
This Avianca deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/3010:10 am
PTY
-
CLO
1 stop4h 00m
Avianca
Mon 5/412:50 pm
CLO
-
PTY
1 stop4h 10m
Avianca
Deal found 4/27$296
This FlightHub deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/134:25 am
PTY
-
CLO
1 stop5h 55m
Avianca
Mon 5/187:55 am
CLO
-
PTY
1 stop6h 20m
Avianca
Deal found 4/27$300
This Copa Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/259:55 pm
PTY
-
CLO
Nonstop1h 41m
Copa Airlines
Thu 4/3012:06 pm
CLO
-
PTY
Nonstop1h 34m
Copa Airlines
Deal found 4/23$305
This Copa Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/309:25 am
PTY
-
CLO
Nonstop1h 41m
Copa Airlines
Sun 5/36:31 pm
CLO
-
PTY
Nonstop1h 34m
Copa Airlines
Deal found 4/27$306

Find flight deals from Panama City to Cali

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Cali (CLO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 28, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$269
(Copa Airlines)

One-way from

$125
(Super.com)

Popular in

December

Cheapest in

February

Average price

$242

Good round-trip deal

$158 or less

Good one-way deal

$154 or less
Provider with most accurate pricing for Panama City Tocumen Intl-Cali Alfonso B. Aragon Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Panama City Tocumen Intl-Cali Alfonso B. Aragon Intl flights.
Search Deals
From Panama City Tocumen Intl to Cali Alfonso B. Aragon Intl
Search Deals
One-way flight from Panama City Tocumen Intl to Cali Alfonso B. Aragon Intl
Search Deals
Highest demand for flights based on searches. 8% potential increase in price ($25 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($4 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals
Price to beat on a round-trip flight from Panama City Tocumen Intl to Cali Alfonso B. Aragon Intl.
Search Deals
Price to beat on a one-way flight from Panama City Tocumen Intl to Cali Alfonso B. Aragon Intl.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Cali that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 28, 2026.
Use the filters below to find and compare flights from Panama City to Cali that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Mon 6/1

9:25 am-11:06 am

Nonstop1h 41m

Cali Alfonso B. Aragon Intl

Sun 6/7

8:46 am-10:20 am

Nonstop1h 34m

$269

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Fri 5/1

3:55 pm-5:36 pm

Nonstop1h 41m

Cali Alfonso B. Aragon Intl

Sun 5/3

6:31 pm-8:05 pm

Nonstop1h 34m

$269

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Fri 5/1

3:55 pm-5:36 pm

Nonstop1h 41m

Cali Alfonso B. Aragon Intl

Mon 5/11

12:06 pm-1:40 pm

Nonstop1h 34m

$269

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Fri 5/1

3:55 pm-5:36 pm

Nonstop1h 41m

Cali Alfonso B. Aragon Intl

Sat 5/9

12:06 pm-1:40 pm

Nonstop1h 34m

$269

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Mon 5/18

12:29 pm-2:10 pm

Nonstop1h 41m

Cali Alfonso B. Aragon Intl

Sun 5/31

12:06 pm-1:40 pm

Nonstop1h 34m

$269

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Fri 5/15

9:25 am-11:06 am

Nonstop1h 41m

Cali Alfonso B. Aragon Intl

Sat 5/23

8:46 am-10:20 am

Nonstop1h 34m

$269

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Fri 6/5

12:29 pm-2:10 pm

Nonstop1h 41m

Cali Alfonso B. Aragon Intl

Mon 6/8

12:06 pm-1:40 pm

Nonstop1h 34m

$269

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Fri 5/22

9:25 am-11:06 am

Nonstop1h 41m

Cali Alfonso B. Aragon Intl

Mon 5/25

3:10 pm-4:44 pm

Nonstop1h 34m

$269

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Wed 5/6

12:29 pm-2:10 pm

Nonstop1h 41m

Cali Alfonso B. Aragon Intl

Fri 5/22

12:06 pm-1:40 pm

Nonstop1h 34m

$269

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Fri 5/22

9:25 am-11:06 am

Nonstop1h 41m

Cali Alfonso B. Aragon Intl

Sun 5/24

12:06 pm-1:40 pm

Nonstop1h 34m

$269

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/23

Showing 1-10 of 19 resultsSorted by cheapest first
1
2
  • Most accurate provider: When it comes to deals on Panama City-Cali flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City-Cali flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City-Cali flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Panama City-Cali flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City-Cali flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Panama City to Cali

Have a flexible travel schedule? Discover the best time to fly to Cali from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Cali

How far ahead should I book a flight from Panama City to Cali?

The best time to book flights from Panama City to Cali is 48 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Panama City to Cali?

Currently, February is the cheapest month in which you can book a flight from Panama City to Cali (average of $241). Flying from Panama City to Cali in December is currently the most expensive (average of $302). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PTY to CLO?

Find hourly flight availability from Panama City to Cali. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 28, 2026.

When flying from Panama City to Cali, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

How much does it cost to fly round-trip from Panama City to Cali?

Reviews of airlines servicing Cali

Get insights into the airlines that provide service to Cali. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cali. Reviews last updated April 28, 2026.
Read through reviews of airlines operating flights from Panama City to Cali, such as Copa Airlines and Avianca. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.5
Good
1,580 reviews

Food

6.8

Boarding

7.8

Entertainment

6.8

Comfort

7.4

Crew

8.1

Overall

7.5

Reviews

1 / 20
2.0
Mediocre

Katerine,Mar 2026

LAX - PTY

Really i was expecting be more friendly with family’s, more when you travel with a infant. We expected like a priority to boarding or be friendly with the spots on the aeroplane.
Copa Airlines
7.5
Good
1,580 reviews
Copa Airlines
7.5
Good
1,580 reviews

Food

6.8

Boarding

7.8

Entertainment

6.8

Comfort

7.4

Crew

8.1

Overall

7.5

Reviews

1 / 20
2.0
Mediocre

Katerine,Mar 2026

LAX - PTY

Really i was expecting be more friendly with family’s, more when you travel with a infant. We expected like a priority to boarding or be friendly with the spots on the aeroplane.
Avianca
6.5
Okay
2,514 reviews
Copa Airlines
7.5
Good
1,580 reviews

Food

6.8

Boarding

7.8

Entertainment

6.8

Comfort

7.4

Crew

8.1

Overall

7.5

Reviews

1 / 20
2.0
Mediocre

Katerine,Mar 2026

LAX - PTY

Really i was expecting be more friendly with family’s, more when you travel with a infant. We expected like a priority to boarding or be friendly with the spots on the aeroplane.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Cali. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Panama City to Cali?

    You will need to book a flight from Panama City Tocumen Intl to Cali Alfonso B. Aragon Intl if you want to fly from Panama City to Cali. At least 3 different airlines have flights from Tocumen Intl (PTY) to Alfonso B. Aragon Intl (CLO) on a regular basis. There are 7 flights to Cali from the Panama City airport per day. If you manage to book one that is nonstop, then you can expect the flight time from PTY to CLO to be around 1h 30m.

  • How popular is this Panama City to Cali flight route?

    This flight path from Panama City Tocumen Intl to Cali Alfonso B. Aragon Intl was viewed by 1 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Panama City to Cali?

    Departing from Panama City to Cali will take you 1h 41m. The distance from Panama City to Cali is about 434 mi. Most flights are nonstop.

  • What are the cheapest airlines flying from Panama City to Cali round-trip?

    Flying on Wingo is currently your cheapest option to Cali, with prices starting at $71. Additional round-trip tickets that might be worth considering are offered by Copa Airlines and Avianca, with the lowest prices starting at $112 and $162, respectively. You may be able to fly from Panama City to Cali for 72% less than the average price by searching for these airlines.

  • What are the cheapest airlines to fly from Panama City to Cali one-way?

    For one-way options, check prices for Wingo. According to our data, you can fly for as low as $71. Users have also found prices from $123 and $125 on Copa Airlines and Avianca, respectively.

  • What are the most reliable airlines from Panama City to Cali?

    No one likes to see their flight delayed. When booking a flight from Panama City to Cali consider choosing United Airlines (96%), KLM (93%) or Turkish Airlines (93%) as they are the most reliable in getting you off to your destination on time.

  • What are the cheapest flights from Panama City to Cali?

    Looking at all options, your cheapest flight can be booked for $181. While the most popular route (Panama City Tocumen Intl - Cali Alfonso B. Aragon Intl) can be booked for $183 on average, our data indicates $288 when flying from Panama City to Cali.

  • Can I find deals for flights from Panama City to Cali that include hotel bookings?

    Yes. In addition to deals on Panama City to Cali flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Cali?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Cali.

  • Can I find deals for business class flights from Panama City to Cali?

    Yes. Cheapflights offers flight deals from Panama City to Cali by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Cali?

    Currently, February is the cheapest month in which you can book a flight from Panama City to Cali (average of $241). Flying from Panama City to Cali in December is currently the most expensive (average of $302). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 3 airlines flying from Panama City to Cali

Discover the top 3 airlines that operate flights from Panama City to Cali. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 28, 2026.
AirlineCheapestAverageFlexibilityOn-time
WingoCheapest$71Average$162FlexibilityNo cancel feeOn-time83%
Copa AirlinesCheapest$112Average$270FlexibilityNo cancel feeOn-time70%
AviancaCheapest$162Average$301FlexibilityNo cancel feeOn-time71%

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