$162+ Cheap flights from Panama City (PTY) to Cali (CLO)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/21. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — CLO
Oct 12 — Oct 191
Round-trip
1 adult, Economy
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Find cheap flights from Panama City to Cali with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Panama City Tocumen Intl to Cali Alfonso B. Aragon Intl are usually found in March or February, booked 29 days in advance, depart on a Saturday or Thursday and return on a Sunday
Cheap flight deals from Panama City to Cali
Cheapest
Best
Last-minute
One-way
Cheapest flights from Panama City to CaliExplore the most affordable flight options available from Panama City to Cali. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 12, 2026.
Explore the most affordable flight options available from Panama City to Cali. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 12, 2026.
This Copa Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/253:39 pm -
Nonstop1h 42m
Mon 9/286:38 pm -
Nonstop1h 32m
Deal found 9/11![Copa Airlines logo]()
$316
This Avianca deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/210:05 am -
1 stop4h 30m
Thu 11/59:20 am -
1 stop5h 55m
Deal found 9/10![Avianca logo]()
$323
This Avianca deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/115:55 pm -
1 stop5h 30m
Tue 9/1510:15 am -
1 stop4h 00m
Deal found 9/9![Avianca logo]()
$324
This Copa Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/1312:34 pm -
Nonstop1h 38m
Wed 9/235:02 am -
Nonstop1h 32m
Deal found 9/9![Copa Airlines logo]()
$326
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/3012:34 pm -
Nonstop1h 38m
Fri 10/96:25 pm -
Nonstop1h 34m
Deal found 9/11![Copa Airlines logo]()
$346
This Copa Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/319:55 pm -
Nonstop1h 42m
Wed 11/48:42 am -
Nonstop1h 38m
Deal found 9/7![Copa Airlines logo]()
$348
This FlightHub deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/13:10 pm -
1 stop5h 55m
Wed 10/79:45 am -
1 stop4h 30m
Deal found 9/11![Avianca logo]()
$349
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/212:28 pm -
Nonstop1h 42m
Mon 10/58:46 am -
Nonstop1h 34m
Deal found 9/11![Copa Airlines logo]()
$351
This Copa Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/512:29 pm -
Nonstop1h 37m
Sat 12/123:12 pm -
Nonstop1h 40m
Deal found 9/10![Copa Airlines logo]()
$369
This Avianca deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/910:05 am -
1 stop4h 30m
Wed 12/1612:50 pm -
1 stop4h 25m
Deal found 9/9![Avianca logo]()
$372
This Avianca deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/74:10 pm -
1 stop5h 35m
Fri 12/256:40 pm -
1 stop6h 40m
Deal found 9/11![Avianca logo]()
$373
This Avianca deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/303:10 pm -
1 stop4h 50m
Tue 10/67:50 pm -
1 stop4h 45m
Deal found 9/11![Avianca logo]()
$375
Best flights from Panama City to CaliDiscover carefully curated flight deals from Panama City to Cali that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 12, 2026.
Discover carefully curated flight deals from Panama City to Cali that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 12, 2026.
This Copa Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/69:24 am -
Nonstop1h 42m
Sun 10/118:46 am -
Nonstop1h 34m
Deal found 9/10![Copa Airlines logo]()
$316
This Copa Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/259:20 am -
Nonstop1h 37m
Mon 11/308:42 am -
Nonstop1h 38m
Deal found 9/11![Copa Airlines logo]()
$316
This Copa Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/69:20 am -
Nonstop1h 37m
Mon 11/96:08 pm -
Nonstop1h 41m
Deal found 9/8![Copa Airlines logo]()
$316
This Copa Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/212:28 pm -
Nonstop1h 42m
Wed 10/73:10 pm -
Nonstop1h 34m
Deal found 9/10![Copa Airlines logo]()
$316
This Copa Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/213:39 pm -
Nonstop1h 42m
Mon 10/268:46 am -
Nonstop1h 34m
Deal found 9/9![Copa Airlines logo]()
$316
This Copa Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/2312:34 pm -
Nonstop1h 38m
Sat 10/108:46 am -
Nonstop1h 34m
Deal found 9/11![Copa Airlines logo]()
$348
This Copa Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/309:20 am -
Nonstop1h 37m
Thu 12/108:40 am -
Nonstop1h 40m
Deal found 9/11![Copa Airlines logo]()
$369
This Copa Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/912:29 pm -
Nonstop1h 37m
Wed 12/168:40 am -
Nonstop1h 40m
Deal found 9/9![Copa Airlines logo]()
$369
Last-minute flights from Panama City to CaliDiscover last-minute flight deals from Panama City to Cali. Data last updated September 12, 2026 and is based on user searches.
Discover last-minute flight deals from Panama City to Cali. Data last updated September 12, 2026 and is based on user searches.
This Avianca deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/115:55 pm -
1 stop5h 10m
Mon 9/1411:10 am -
1 stop5h 50m
Deal found 9/9![Avianca logo]()
$323
This Avianca deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/115:55 pm -
1 stop5h 30m
Tue 9/1510:15 am -
1 stop4h 00m
Deal found 9/9![Avianca logo]()
$324
This Copa Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/119:55 pm -
Nonstop1h 38m
Fri 9/186:38 pm -
Nonstop1h 32m
Deal found 9/11![Copa Airlines logo]()
$378
This Copa Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/1312:34 pm -
Nonstop1h 38m
Wed 9/235:02 am -
Nonstop1h 32m
Deal found 9/9![Copa Airlines logo]()
$326
This Copa Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/253:39 pm -
Nonstop1h 42m
Mon 9/286:38 pm -
Nonstop1h 32m
Deal found 9/11![Copa Airlines logo]()
$316
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/3012:34 pm -
Nonstop1h 38m
Fri 10/96:25 pm -
Nonstop1h 34m
Deal found 9/11![Copa Airlines logo]()
$346
This Avianca deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/303:10 pm -
1 stop4h 50m
Tue 10/67:50 pm -
1 stop4h 45m
Deal found 9/11![Avianca logo]()
$375
This FlightHub deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/13:10 pm -
1 stop5h 55m
Wed 10/79:45 am -
1 stop4h 30m
Deal found 9/11![Avianca logo]()
$349
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/212:28 pm -
Nonstop1h 42m
Mon 10/58:46 am -
Nonstop1h 34m
Deal found 9/11![Copa Airlines logo]()
$351
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/29:55 pm -
Nonstop1h 42m
Fri 10/93:10 pm -
Nonstop1h 34m
Deal found 9/11![Copa Airlines logo]()
$390
This Copa Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/319:55 pm -
Nonstop1h 42m
Wed 11/48:42 am -
Nonstop1h 38m
Deal found 9/7![Copa Airlines logo]()
$348
This Copa Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/3112:29 pm -
Nonstop1h 42m
Thu 11/512:05 pm -
Nonstop1h 38m
Deal found 9/9![Copa Airlines logo]()
$386
One-way flights from Panama City to CaliSearch for one-way flight options from Panama City to Cali. Find affordable one-way fares based on user searches. Data last updated September 12, 2026.
Search for one-way flight options from Panama City to Cali. Find affordable one-way fares based on user searches. Data last updated September 12, 2026.
This Super.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/213:55 pm -
Nonstop1h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Copa Airlines logo]()
$162
This Copa Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/209:30 am -
Nonstop1h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![Copa Airlines logo]()
$165
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/101:25 pm -
1 stop17h 44m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Multiple Airlines logo]()
$190
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/216:50 am -
1 stop10h 12m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Multiple Airlines logo]()
$202
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/238:15 am -
2 stops7h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![Multiple Airlines logo]()
$215
This Copa Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/412:29 pm -
Nonstop1h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![Copa Airlines logo]()
$219
This Copa Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/314:09 pm -
Nonstop1h 42m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![Copa Airlines logo]()
$236
This Copa Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/303:27 pm -
Nonstop1h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![Copa Airlines logo]()
$273
This Copa Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/169:55 pm -
Nonstop1h 37m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![Copa Airlines logo]()
$292
This Avianca deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/2010:10 am -
1 stop5h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Avianca logo]()
$365
Find flight deals from Panama City to Cali
Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Cali (CLO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 12, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $316 (Copa Airlines) |
One-way from | $162 (Super.com) |
Popular in | December |
Cheapest in | March |
Average price | $267 |
Good round-trip deal | $175 or less |
Good one-way deal | $137 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Panama City to Cali that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 12, 2026.
Use the filters below to find and compare flights from Panama City to Cali that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
Panama CityCali
PTY Panama City Tocumen Intl - CLO Cali Alfonso B. Aragon Intl
PTYCLO
Panama City Tocumen Intl
Sun 11/15
3:55 pm-5:32 pm
Nonstop1h 37m
Cali Alfonso B. Aragon Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$165
Panama CityCali
PTY Panama City Tocumen Intl - CLO Cali Alfonso B. Aragon Intl
PTYCLO
Panama City Tocumen Intl
Wed 9/16
12:34 pm-2:12 pm
Nonstop1h 38m
Cali Alfonso B. Aragon Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$165
Panama CityCali
PTY Panama City Tocumen Intl - CLO Cali Alfonso B. Aragon Intl
PTYCLO
Panama City Tocumen Intl
Tue 11/10
12:29 pm-2:06 pm
Nonstop1h 37m
Cali Alfonso B. Aragon Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$165
Panama CityCali
PTY Panama City Tocumen Intl - CLO Cali Alfonso B. Aragon Intl
PTYCLO
Panama City Tocumen Intl
Fri 10/2
12:28 pm-2:10 pm
Nonstop1h 42m
Cali Alfonso B. Aragon Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$165
Panama CityCali
PTY Panama City Tocumen Intl - CLO Cali Alfonso B. Aragon Intl
PTYCLO
Panama City Tocumen Intl
Sun 9/27
12:34 pm-2:12 pm
Nonstop1h 38m
Cali Alfonso B. Aragon Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$165
Panama CityCali
PTY Panama City Tocumen Intl - CLO Cali Alfonso B. Aragon Intl
PTYCLO
Panama City Tocumen Intl
Sat 9/19
3:55 pm-5:33 pm
Nonstop1h 38m
Cali Alfonso B. Aragon Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$165
Panama CityCali
PTY Panama City Tocumen Intl - CLO Cali Alfonso B. Aragon Intl
PTYCLO
Panama City Tocumen Intl
Wed 1/20
3:55 pm-5:34 pm
Nonstop1h 39m
Cali Alfonso B. Aragon Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$165
Panama CityCali
PTY Panama City Tocumen Intl - CLO Cali Alfonso B. Aragon Intl
PTYCLO
Panama City Tocumen Intl
Fri 10/16
12:28 pm-2:10 pm
Nonstop1h 42m
Cali Alfonso B. Aragon Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$165
Panama CityCali
PTY Panama City Tocumen Intl - CLO Cali Alfonso B. Aragon Intl
PTYCLO
Panama City Tocumen Intl
Fri 9/18
9:30 am-11:08 am
Nonstop1h 38m
Cali Alfonso B. Aragon Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$165
Panama CityCali
PTY Panama City Tocumen Intl - CLO Cali Alfonso B. Aragon Intl
PTYCLO
Panama City Tocumen Intl
Sun 9/20
9:30 am-11:08 am
Nonstop1h 38m
Cali Alfonso B. Aragon Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$165
Showing 1-10 of 18 resultsSorted by cheapest first
- Most accurate provider: When it comes to deals on Panama City-Cali flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City-Cali flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City-Cali flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Panama City-Cali flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City-Cali flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Panama City to Cali
Have a flexible travel schedule? Discover the best time to fly to Cali from Panama City with our price prediction graph.
PTY-CLO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Panama City to Cali
Prices
Airlines
Delays
How far ahead should I book a flight from Panama City to Cali?
The best time to book flights from Panama City to Cali is 28 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
What is the cheapest month to book a flight from Panama City to Cali?
Currently, March is the cheapest month in which you can book a flight from Panama City to Cali (average of $228). Flying from Panama City to Cali in December is currently the most expensive (average of $304). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from PTY to CLO?
Find hourly flight availability from Panama City to Cali. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 12, 2026.
When flying from Panama City to Cali, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
How often are flights from Panama City to Cali delayed?
About 5% of weekly flights between Panama City and Cali have experienced delays in the past year, with the average delay time being 98 minutes.
What is the most punctual flight time for Panama City to Cali flights?
Historically, flights departing at night are less likely to be delayed, whereas flights leaving in the early afternoon tend to experience delays more often.
What day of the week experiences the fewest flight delays on this route?
Wednesday tends to have the lowest number of delays on this route, whereas Tuesday has historically faced a higher average of delays compared to other days of the week.
Which airline has the best punctuality record on Panama City to Cali flights?
Over the last year, Copa Airlines have had the lowest number of delays on this route, with just 5% of flights being delayed.
Reviews of airlines servicing Cali
Get insights into the airlines that provide service to Cali. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cali. Reviews last updated September 12, 2026.
Read through reviews of airlines operating flights from Panama City to Cali, such as Copa Airlines and Avianca. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.4
Crew
8.1
Food
6.9
Overall
7.6
Boarding
7.8
Entertainment
6.9
Reviews
1 / 20
2.0
MediocreMaria,Dec 2025
PTY - SLA
Comfort
7.4
Crew
8.1
Food
6.9
Overall
7.6
Boarding
7.8
Entertainment
6.9
Reviews
1 / 20
2.0
MediocreMaria,Dec 2025
PTY - SLA
Comfort
7.4
Crew
8.1
Food
6.9
Overall
7.6
Boarding
7.8
Entertainment
6.9
Reviews
1 / 20
2.0
MediocreMaria,Dec 2025
PTY - SLA
Related info for your journey
Find useful and relevant information for your journey from Panama City to Cali. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Panama City to Cali
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Other flights to Cali
Explore flights to Cali departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 12, 2026.
Complete your trip
Complete your trip to Cali by adding a car rental and/or hotel reservation to your travel itinerary.
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Find flights from Panama City to Cali, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Panama City and Cali flights
Browse other Panama City and Cali flight options. Last updated on September 12, 2026.
Other flights from Panama City
Browse through other flights departing from Panama City. Flights are based on user searches made on Cheapflights and were last updated on September 12, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from Panama City to Cali
Discover the top 3 airlines that operate flights from Panama City to Cali. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 12, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$101 | Average$185 | FlexibilityNo cancel fee | On-time83% | |
| Cheapest$113 | Average$314 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$162 | Average$314 | FlexibilityNo cancel fee | On-time71% |