$314+ Cheap flights from Panama City (PTY) to Charlotte (CLT)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/26. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — CLT
Nov 24 — Dec 11
Round-trip
1 adult, Economy
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Find cheap flights from Panama City to Charlotte with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Panama City to Charlotte
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Cheapest flights from Panama City to CharlotteExplore the most affordable flight options available from Panama City to Charlotte. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 25, 2026.
Explore the most affordable flight options available from Panama City to Charlotte. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 25, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1212:33 pm -
1 stop9h 00m
Thu 11/266:01 pm -
1 stop14h 43m
Deal found 10/20![Multiple Airlines logo]()
$564
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/238:00 am -
1 stop13h 37m
Sat 1/211:54 am -
1 stop9h 51m
Deal found 10/22![Delta logo]()
$575
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/163:29 pm -
1 stop19h 45m
Fri 11/2712:20 pm -
1 stop25h 45m
Deal found 10/20![Delta logo]()
$585
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/43:24 pm -
1 stop8h 30m
Wed 11/185:30 am -
1 stop8h 32m
Deal found 10/21![Delta logo]()
$595
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/213:30 pm -
1 stop8h 27m
Sun 11/296:31 am -
1 stop7h 31m
Deal found 10/22![Delta logo]()
$596
This Delta deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/93:29 pm -
1 stop8h 28m
Tue 11/246:31 am -
1 stop7h 31m
Deal found 10/24![Delta logo]()
$616
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/233:29 pm -
1 stop8h 28m
Sun 11/295:30 am -
1 stop8h 32m
Deal found 10/20![Delta logo]()
$620
This Kiwi.com deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1912:33 pm -
1 stop9h 00m
Fri 12/46:35 pm -
1 stop12h 00m
Deal found 10/24![Multiple Airlines logo]()
$635
This Kiwi.com deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/209:31 pm -
1 stop19h 34m
Fri 12/46:35 pm -
1 stop12h 00m
Deal found 10/24![Multiple Airlines logo]()
$636
Best flights from Panama City to CharlotteDiscover carefully curated flight deals from Panama City to Charlotte that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 25, 2026.
Discover carefully curated flight deals from Panama City to Charlotte that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 25, 2026.
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/238:00 am -
1 stop13h 37m
Sat 1/211:54 am -
1 stop9h 51m
Deal found 10/22![Delta logo]()
$575
This United Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1711:55 pm -
2 stops20h 56m
Mon 1/48:07 am -
2 stops21h 03m
Deal found 10/24![United Airlines logo]()
$669
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/163:29 pm -
1 stop19h 45m
Sat 11/286:31 am -
1 stop7h 34m
Deal found 10/20![Delta logo]()
$585
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/183:29 pm -
1 stop24h 40m
Fri 11/2710:59 am -
1 stop27h 06m
Deal found 10/20![Delta logo]()
$585
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/2311:55 pm -
2 stops20h 56m
Sat 1/26:20 am -
1 stop13h 18m
Deal found 10/20![United Airlines logo]()
$680
This United Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/124:41 pm -
2 stops24h 42m
Tue 1/263:04 pm -
2 stops28h 58m
Deal found 10/23![United Airlines logo]()
$702
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/183:29 pm -
1 stop8h 28m
Thu 11/266:00 am -
1 stop8h 02m
Deal found 10/21![Delta logo]()
$669
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/223:29 pm -
1 stop17h 13m
Tue 12/15:30 am -
1 stop8h 33m
Deal found 10/20![Delta logo]()
$680
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/183:29 pm -
1 stop26h 38m
Mon 11/302:19 pm -
1 stop23h 44m
Deal found 10/20![Delta logo]()
$731
Last-minute flights from Panama City to CharlotteDiscover last-minute flight deals from Panama City to Charlotte. Data last updated October 25, 2026 and is based on user searches.
Discover last-minute flight deals from Panama City to Charlotte. Data last updated October 25, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/43:24 pm -
1 stop8h 30m
Wed 11/185:30 am -
1 stop8h 32m
Deal found 10/21![Delta logo]()
$595
This Delta deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/93:29 pm -
1 stop8h 28m
Tue 11/246:31 am -
1 stop7h 31m
Deal found 10/24![Delta logo]()
$616
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1212:33 pm -
1 stop9h 00m
Thu 11/266:01 pm -
1 stop14h 43m
Deal found 10/20![Multiple Airlines logo]()
$564
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/163:29 pm -
1 stop17h 13m
Sun 11/296:31 am -
1 stop7h 31m
Deal found 10/20![Delta logo]()
$585
This Kiwi.com deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1912:33 pm -
1 stop9h 00m
Fri 12/46:35 pm -
1 stop12h 00m
Deal found 10/24![Multiple Airlines logo]()
$635
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1912:33 pm -
1 stop9h 00m
Thu 12/38:54 am -
1 stop11h 25m
Deal found 10/20![Multiple Airlines logo]()
$645
This Kiwi.com deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/209:31 pm -
1 stop19h 34m
Fri 12/46:35 pm -
1 stop12h 00m
Deal found 10/24![Multiple Airlines logo]()
$636
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/213:30 pm -
1 stop8h 27m
Sun 11/296:31 am -
1 stop7h 31m
Deal found 10/22![Delta logo]()
$596
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/233:29 pm -
1 stop8h 28m
Sun 11/295:30 am -
1 stop8h 32m
Deal found 10/20![Delta logo]()
$620
One-way flights from Panama City to CharlotteSearch for one-way flight options from Panama City to Charlotte. Find affordable one-way fares based on user searches. Data last updated October 25, 2026.
Search for one-way flight options from Panama City to Charlotte. Find affordable one-way fares based on user searches. Data last updated October 25, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/269:31 pm -
1 stop19h 34m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Multiple Airlines logo]()
$314
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/298:00 am -
1 stop11h 58m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Delta logo]()
$321
This Kiwi.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/238:16 am -
1 stop8h 49m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Multiple Airlines logo]()
$339
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/294:41 pm -
2 stops28h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![United Airlines logo]()
$363
This Kiwi.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/19:31 pm -
3 stops26h 13m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Multiple Airlines logo]()
$366
This Kiwi.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/292:47 pm -
2 stops33h 47m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Multiple Airlines logo]()
$531
Find flight deals from Panama City to Charlotte
Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Charlotte (CLT). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 25, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $564 (Kiwi.com) |
One-way from | $314 (Kiwi.com) |
Popular in | March |
Cheapest in | December |
Average price | $571 |
Cheapflights Fare Finder
Customize your flight search to find flights from Panama City to Charlotte that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 25, 2026.
Use the filters below to find and compare flights from Panama City to Charlotte that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
Panama CityCharlotte
PTY Panama City Tocumen Intl - CLT Charlotte Douglas
PTYCLT
Panama City Tocumen Intl
Tue 12/29
8:00 am-7:58 pm
1 stop11h 58m
Charlotte Douglas
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$355
Panama CityCharlotte
PTY Panama City Tocumen Intl - CLT Charlotte Douglas
PTYCLT
Panama City Tocumen Intl
Tue 12/29
4:41 pm-8:51 pm
2 stops28h 10m
Charlotte Douglas
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$363
Panama CityCharlotte
PTY Panama City Tocumen Intl - CLT Charlotte Douglas
PTYCLT
Panama City Tocumen Intl
Wed 12/23
8:00 am-9:37 pm
1 stop13h 37m
Charlotte Douglas
Sat 1/2
11:54 am-9:45 pm
1 stop9h 51m
$575
Panama CityCharlotte
PTY Panama City Tocumen Intl - CLT Charlotte Douglas
PTYCLT
Panama City Tocumen Intl
Mon 11/16
3:29 pm-11:14 am
1 stop19h 45m
Charlotte Douglas
Sat 11/28
6:31 am-2:05 pm
1 stop7h 34m
$585
Panama CityCharlotte
PTY Panama City Tocumen Intl - CLT Charlotte Douglas
PTYCLT
Panama City Tocumen Intl
Wed 11/18
3:29 pm-4:09 pm
1 stop24h 40m
Charlotte Douglas
Fri 11/27
10:59 am-2:05 pm
1 stop27h 06m
$585
Panama CityCharlotte
PTY Panama City Tocumen Intl - CLT Charlotte Douglas
PTYCLT
Panama City Tocumen Intl
Thu 12/17
11:55 pm-8:51 pm
2 stops20h 56m
Charlotte Douglas
Mon 1/4
8:07 am-5:10 am
2 stops21h 03m
$669
Panama CityCharlotte
PTY Panama City Tocumen Intl - CLT Charlotte Douglas
PTYCLT
Panama City Tocumen Intl
Wed 11/18
3:29 pm-11:57 pm
1 stop8h 28m
Charlotte Douglas
Thu 11/26
6:00 am-2:02 pm
1 stop8h 02m
$669
Panama CityCharlotte
PTY Panama City Tocumen Intl - CLT Charlotte Douglas
PTYCLT
Panama City Tocumen Intl
Wed 12/23
11:55 pm-8:51 pm
2 stops20h 56m
Charlotte Douglas
Sat 1/2
6:20 am-7:38 pm
1 stop13h 18m
$680
Panama CityCharlotte
PTY Panama City Tocumen Intl - CLT Charlotte Douglas
PTYCLT
Panama City Tocumen Intl
Sun 11/22
3:29 pm-8:42 am
1 stop17h 13m
Charlotte Douglas
Tue 12/1
5:30 am-2:03 pm
1 stop8h 33m
$680
Panama CityCharlotte
PTY Panama City Tocumen Intl - CLT Charlotte Douglas
PTYCLT
Panama City Tocumen Intl
Tue 1/12
4:41 pm-5:23 pm
2 stops24h 42m
Charlotte Douglas
Tue 1/26
3:04 pm-8:02 pm
2 stops28h 58m
$702
Showing 1-10 of 13 resultsSorted by cheapest first
Compare providers for flights from Panama City to Charlotte
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to Charlotte in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Panama City-Charlotte flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City-Charlotte flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City-Charlotte flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Panama City-Charlotte flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City-Charlotte flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Panama City to Charlotte
Have a flexible travel schedule? Discover the best time to fly to Charlotte from Panama City with our price prediction graph.
PTY-CLT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Panama City to Charlotte
What is the cheapest month to book a flight from Panama City to Charlotte?
Currently, December is the cheapest month in which you can book a flight from Panama City to Charlotte (average of $498). Flying from Panama City to Charlotte in March is currently the most expensive (average of $771). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Panama City to Charlotte?
Airfare is below average for this route at the moment.
Panama City to Charlotte flights typically cost between $567 and $661 in November.The cheapest round-trip price found within the last 5 days was $564 on Multiple Airlines (Nov 12-Nov 26).
Reviews of airlines servicing Charlotte
Get insights into the airlines that provide service to Charlotte. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Charlotte. Reviews last updated October 25, 2026.
Read through reviews of airlines operating flights from Panama City to Charlotte, such as United Airlines and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.3
Boarding
7.7
Food
6.7
Entertainment
7.1
Comfort
7.3
Crew
8.1
Reviews
1 / 20
8.0
ExcellentAsha,Sep 2026
LGA - IAH
Overall
7.3
Boarding
7.7
Food
6.7
Entertainment
7.1
Comfort
7.3
Crew
8.1
Reviews
1 / 20
8.0
ExcellentAsha,Sep 2026
LGA - IAH
Overall
7.3
Boarding
7.7
Food
6.7
Entertainment
7.1
Comfort
7.3
Crew
8.1
Reviews
1 / 20
8.0
ExcellentAsha,Sep 2026
LGA - IAH
Related info for your journey
Find useful and relevant information for your journey from Panama City to Charlotte. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Charlotte?
Book flights to Charlotte if you plan to visit one of these locationsRock Hill
Gastonia
Salisbury
Cornelius
Morganton
Mooresville
Huntersville
Matthews
Boone
Hickory
Shelby
Gaffney
Statesville
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Other flights to Charlotte
Explore flights to Charlotte departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 25, 2026.
Complete your trip
Complete your trip to Charlotte by adding a car rental and/or hotel reservation to your travel itinerary.
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Find flights from Panama City to Charlotte, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Panama City and Charlotte flights
Browse other Panama City and Charlotte flight options. Last updated on October 25, 2026.
Other flights from Panama City
Browse through other flights departing from Panama City. Flights are based on user searches made on Cheapflights and were last updated on October 25, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Panama City to Charlotte
Discover the top 2 airlines that operate flights from Panama City to Charlotte. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 25, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$442 | Average$512 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$544 | Average$707 | FlexibilityNo cancel fee | On-time69% |