$270+ Cheap flights from San Diego (SAN) to Panama
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/11. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — PTY
Jun 19 — Jun 261
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from San Diego to Panama with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from San Diego to Panama
Cheapest
Best
Last-minute
One-way
Cheapest flights from San Diego to PanamaExplore the most affordable flight options available from San Diego to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 20, 2026.
Explore the most affordable flight options available from San Diego to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 20, 2026.
This Avianca deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/37:59 pm
SAN
- PTY
2 stops12h 31m
Multiple Airlines
Mon 9/75:30 am
PTY
- SAN
2 stops13h 40m
Multiple Airlines
Deal found 5/17![Multiple Airlines logo]()
$533
This Avianca deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/247:59 pm
SAN
- PTY
2 stops12h 31m
Multiple Airlines
Mon 9/285:30 am
PTY
- SAN
2 stops13h 40m
Multiple Airlines
Deal found 5/18![Multiple Airlines logo]()
$538
This Avianca deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/247:59 pm
SAN
- PTY
2 stops12h 31m
Multiple Airlines
Fri 8/285:30 am
PTY
- SAN
2 stops13h 40m
Multiple Airlines
Deal found 5/20![Multiple Airlines logo]()
$548
This Avianca deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1110:04 am
SAN
- PTY
2 stops13h 51m
Multiple Airlines
Tue 8/185:30 am
PTY
- SAN
2 stops12h 27m
Multiple Airlines
Deal found 5/17![Multiple Airlines logo]()
$553
This Avianca deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1911:20 am
SAN
- PTY
2 stops12h 35m
Multiple Airlines
Tue 8/255:30 am
PTY
- SAN
2 stops12h 41m
Multiple Airlines
Deal found 5/15![Multiple Airlines logo]()
$614
This Orbitz deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/272:33 pm
SAN
- PTY
2 stops17h 57m
Multiple Airlines
Mon 11/23:50 pm
PTY
- SAN
2 stops24h 04m
Multiple Airlines
Deal found 5/16![Multiple Airlines logo]()
$618
This Orbitz deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/201:00 pm
SAN
- PTY
2 stops19h 30m
Multiple Airlines
Wed 8/265:30 am
PTY
- SAN
2 stops15h 32m
Multiple Airlines
Deal found 5/15![Multiple Airlines logo]()
$620
This Orbitz deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1710:04 am
SAN
- PTY
2 stops13h 51m
Multiple Airlines
Sun 8/235:30 am
PTY
- SAN
2 stops32h 50m
Multiple Airlines
Deal found 5/15![Multiple Airlines logo]()
$630
This Expedia deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/237:43 am
SAN
- PTY
2 stops16h 12m
Multiple Airlines
Mon 5/253:50 pm
PTY
- SAN
2 stops28h 37m
Multiple Airlines
Deal found 5/20![Multiple Airlines logo]()
$637
This Expedia deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/281:15 pm
SAN
- PTY
2 stops19h 15m
Multiple Airlines
Wed 6/35:30 am
PTY
- SAN
2 stops15h 53m
Multiple Airlines
Deal found 5/15![Multiple Airlines logo]()
$638
This Avianca deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2810:49 am
SAN
- PTY
2 stops13h 06m
Multiple Airlines
Thu 8/205:30 am
PTY
- SAN
2 stops12h 41m
Multiple Airlines
Deal found 5/17![Multiple Airlines logo]()
$643
This Copa Airlines deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/79:03 pm
SAN
- DAV
1 stop10h 07m
Copa Airlines
Sat 9/128:26 am
DAV
- SAN
2 stops13h 36m
Copa Airlines
Deal found 5/16![Copa Airlines logo]()
$905
Best flights from San Diego to PanamaDiscover carefully curated flight deals from San Diego to Panama that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 20, 2026.
Discover carefully curated flight deals from San Diego to Panama that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 20, 2026.
This Copa Airlines deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/318:58 pm
SAN
- PTY
Nonstop6h 22m
Copa Airlines
Sun 9/131:55 pm
PTY
- SAN
Nonstop6h 35m
Copa Airlines
Deal found 5/20![Copa Airlines logo]()
$696
This United Airlines deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/118:00 am
SAN
- PTY
1 stop8h 37m
United Airlines
Sun 9/1310:00 am
PTY
- SAN
1 stop9h 46m
United Airlines
Deal found 5/18![United Airlines logo]()
$701
This United Airlines deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/316:20 am
SAN
- PTY
2 stops10h 17m
United Airlines
Sun 9/133:30 pm
PTY
- SAN
2 stops19h 13m
United Airlines
Deal found 5/17![United Airlines logo]()
$705
This Copa Airlines deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/610:00 pm
SAN
- PTY
Nonstop6h 22m
Copa Airlines
Wed 7/152:01 pm
PTY
- SAN
Nonstop6h 29m
Copa Airlines
Deal found 5/17![Copa Airlines logo]()
$711
This United Airlines deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/208:00 am
SAN
- PTY
1 stop8h 37m
United Airlines
Sat 9/2610:00 am
PTY
- SAN
2 stops11h 55m
United Airlines
Deal found 5/20![United Airlines logo]()
$715
This United Airlines deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/196:15 am
SAN
- PTY
2 stops10h 22m
United Airlines
Wed 9/2310:00 am
PTY
- SAN
2 stops12h 34m
United Airlines
Deal found 5/18![United Airlines logo]()
$715
This United Airlines deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/65:15 pm
SAN
- PTY
1 stop18h 59m
United Airlines
Wed 7/157:55 am
PTY
- SAN
1 stop13h 55m
United Airlines
Deal found 5/18![United Airlines logo]()
$744
This United Airlines deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/28:32 pm
SAN
- PTY
2 stops17h 40m
United Airlines
Fri 8/77:55 am
PTY
- SAN
2 stops17h 59m
United Airlines
Deal found 5/18![United Airlines logo]()
$748
This United Airlines deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/278:00 am
SAN
- DAV
2 stops23h 08m
United Airlines
Mon 8/319:50 am
DAV
- SAN
2 stops33h 56m
United Airlines
Deal found 5/15![United Airlines logo]()
$1,131
This United Airlines deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/710:13 am
SAN
- DAV
2 stops44h 57m
United Airlines
Sat 9/129:50 am
DAV
- SAN
2 stops33h 56m
United Airlines
Deal found 5/16![United Airlines logo]()
$1,151
This United Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/258:00 am
SAN
- DAV
2 stops23h 08m
United Airlines
Fri 8/289:50 am
DAV
- SAN
2 stops33h 56m
United Airlines
Deal found 5/19![United Airlines logo]()
$1,156
Last-minute flights from San Diego to PanamaDiscover last-minute flight deals from San Diego to Panama. Data last updated May 20, 2026 and is based on user searches.
Discover last-minute flight deals from San Diego to Panama. Data last updated May 20, 2026 and is based on user searches.
This Expedia deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/221:15 pm
SAN
- PTY
2 stops34h 40m
Multiple Airlines
Mon 5/253:50 pm
PTY
- SAN
2 stops30h 39m
Multiple Airlines
Deal found 5/20![Multiple Airlines logo]()
$662
This Expedia deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/2310:13 am
SAN
- PTY
2 stops13h 42m
Multiple Airlines
Wed 5/275:30 am
PTY
- SAN
2 stops14h 57m
Multiple Airlines
Deal found 5/20![Multiple Airlines logo]()
$620
This Expedia deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/237:43 am
SAN
- PTY
2 stops16h 12m
Multiple Airlines
Mon 5/253:50 pm
PTY
- SAN
2 stops28h 37m
Multiple Airlines
Deal found 5/20![Multiple Airlines logo]()
$637
This Expedia deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/257:43 am
SAN
- PTY
2 stops24h 47m
Multiple Airlines
Thu 6/43:50 pm
PTY
- SAN
2 stops18h 08m
Multiple Airlines
Deal found 5/16![Multiple Airlines logo]()
$757
This Expedia deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/281:15 pm
SAN
- PTY
2 stops19h 15m
Multiple Airlines
Wed 6/35:30 am
PTY
- SAN
2 stops15h 53m
Multiple Airlines
Deal found 5/15![Multiple Airlines logo]()
$638
This Travelocity deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/284:17 pm
SAN
- PTY
2 stops16h 13m
Multiple Airlines
Tue 6/23:50 pm
PTY
- SAN
2 stops28h 37m
Multiple Airlines
Deal found 5/15![Multiple Airlines logo]()
$655
This Expedia deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/48:56 am
SAN
- PTY
2 stops14h 59m
Multiple Airlines
Fri 6/195:30 am
PTY
- SAN
2 stops16h 51m
Multiple Airlines
Deal found 5/15![Multiple Airlines logo]()
$787
This Expedia deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/119:05 am
SAN
- PTY
2 stops14h 50m
Multiple Airlines
Tue 6/163:50 pm
PTY
- SAN
2 stops23h 49m
Multiple Airlines
Deal found 5/20![Multiple Airlines logo]()
$759
This United Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/166:15 am
SAN
- DAV
2 stops24h 48m
United Airlines
Tue 6/239:50 am
DAV
- SAN
2 stops37h 34m
United Airlines
Deal found 5/19![United Airlines logo]()
$1,222
This United Airlines deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/175:15 pm
SAN
- PTY
1 stop18h 59m
United Airlines
Wed 6/247:55 am
PTY
- SAN
2 stops16h 30m
United Airlines
Deal found 5/17![United Airlines logo]()
$791
This Copa Airlines deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/2910:00 pm
SAN
- PTY
Nonstop6h 14m
Copa Airlines
Sun 7/52:01 pm
PTY
- SAN
Nonstop6h 29m
Copa Airlines
Deal found 5/20![Copa Airlines logo]()
$777
One-way flights from San Diego to PanamaSearch for one-way flight options from San Diego to Panama. Find affordable one-way fares based on user searches. Data last updated May 20, 2026.
Search for one-way flight options from San Diego to Panama. Find affordable one-way fares based on user searches. Data last updated May 20, 2026.
This Avianca deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/127:01 pm
SAN
- PTY
2 stops13h 29m
Multiple Airlines
Deal found 5/20![Multiple Airlines logo]()
$270
This Expedia deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/139:05 am
SAN
- PTY
2 stops14h 50m
Multiple Airlines
Deal found 5/20![Multiple Airlines logo]()
$272
This Avianca deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/308:35 pm
SAN
- PTY
2 stops11h 55m
Multiple Airlines
Deal found 5/16![Multiple Airlines logo]()
$287
This Avianca deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/288:35 pm
SAN
- PTY
2 stops11h 55m
Multiple Airlines
Deal found 5/17![Multiple Airlines logo]()
$291
This Expedia deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/810:04 am
SAN
- PTY
2 stops13h 51m
Multiple Airlines
Deal found 5/19![Multiple Airlines logo]()
$306
This Avianca deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/58:35 pm
SAN
- PTY
2 stops11h 55m
Multiple Airlines
Deal found 5/20![Multiple Airlines logo]()
$346
This Kiwi.com deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/144:17 pm
SAN
- PTY
3 stops26h 20m
Multiple Airlines
Deal found 5/15![Multiple Airlines logo]()
$350
This Delta deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/139:40 pm
SAN
- PTY
1 stop13h 15m
Delta
Deal found 5/20![Delta logo]()
$365
This Copa Airlines deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/128:58 pm
SAN
- PTY
Nonstop6h 22m
Copa Airlines
Deal found 5/20![Copa Airlines logo]()
$370
This KAYAK deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/86:15 am
SAN
- PTY
1 stop10h 22m
Copa Airlines
Deal found 5/19![Copa Airlines logo]()
$374
This United Airlines deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/146:15 am
SAN
- PTY
1 stop10h 22m
United Airlines
Deal found 5/15![United Airlines logo]()
$375
This Kiwi.com deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/119:57 am
SAN
- PTY
3 stops31h 40m
Multiple Airlines
Deal found 5/16![Multiple Airlines logo]()
$379
Find flight deals from San Diego to Panama
Keep the following information in mind while searching for San Diego to Panama flight deals. Data was last updated May 20, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $533 (Avianca) |
One-way from | $270 (Avianca) |
Popular in | January |
Cheapest in | September |
Average price | $620 |
Good round-trip deal | $541 or less |
Good one-way deal | $279 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from San Diego to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 20, 2026.
Use the filters below to find and compare flights from San Diego to Panama that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San DiegoPanama City
SAN - PTY
SANPTY
San Diego
Mon 8/31
8:58 pm-5:20 am
Nonstop6h 22m
Panama City Tocumen Intl
Sun 9/13
1:55 pm-6:30 pm
Nonstop6h 35m
$696
San DiegoPanama City
SAN - PTY
SANPTY
San Diego
Fri 9/11
8:00 am-6:37 pm
1 stop8h 37m
Panama City Tocumen Intl
Sun 9/13
10:00 am-5:46 pm
1 stop9h 46m
$701
San DiegoPanama City
SAN - PTY
SANPTY
San Diego
Mon 8/31
6:20 am-6:37 pm
2 stops10h 17m
Panama City Tocumen Intl
Sun 9/13
3:30 pm-8:43 am
2 stops19h 13m
$705
Quickest round-trip
San DiegoPanama City
SAN - PTY
SANPTY
San Diego
Mon 7/6
10:00 pm-6:22 am
Nonstop6h 22m
Panama City Tocumen Intl
Wed 7/15
2:01 pm-6:30 pm
Nonstop6h 29m
$711
San DiegoPanama City
SAN - PTY
SANPTY
San Diego
Sun 9/20
8:00 am-6:37 pm
1 stop8h 37m
Panama City Tocumen Intl
Sat 9/26
10:00 am-7:55 pm
2 stops11h 55m
$715
San DiegoPanama City
SAN - PTY
SANPTY
San Diego
Sat 9/19
6:15 am-6:37 pm
2 stops10h 22m
Panama City Tocumen Intl
Wed 9/23
10:00 am-8:34 pm
2 stops12h 34m
$715
San DiegoPanama City
SAN - PTY
SANPTY
San Diego
Mon 7/6
5:15 pm-2:14 pm
1 stop18h 59m
Panama City Tocumen Intl
Wed 7/15
7:55 am-7:50 pm
1 stop13h 55m
$744
San DiegoPanama City
SAN - PTY
SANPTY
San Diego
Thu 7/2
8:32 pm-4:12 pm
2 stops17h 40m
Panama City Tocumen Intl
Fri 8/7
7:55 am-11:54 pm
2 stops17h 59m
$748
San DiegoDavid
SAN - DAV
SANDAV
San Diego
Thu 8/27
8:00 am-9:08 am
2 stops23h 08m
David Enrique Malek
Mon 8/31
9:50 am-5:46 pm
2 stops33h 56m
$1,131
San DiegoDavid
SAN - DAV
SANDAV
San Diego
Mon 9/7
10:13 am-9:10 am
2 stops44h 57m
David Enrique Malek
Sat 9/12
9:50 am-5:46 pm
2 stops33h 56m
$1,151
Showing 1-10 of 18 resultsSorted by cheapest first
Best time to book a flight from San Diego to Panama
Have a flexible travel schedule? Discover the best time to fly to Panama from San Diego with our price prediction graph.
SAN-PTY
SAN-DAV
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Diego to Panama
SAN-PA0
SAN-PTY
SAN-DAV
What is the cheapest month to book a flight from San Diego to Panama?
Currently, September is the cheapest month in which you can book a flight from San Diego to Panama (average of $145). Flying from San Diego to Panama in April is currently the most expensive (average of $510). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from SAN to PA?
Find hourly flight availability from San Diego to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 20, 2026.
When flying from San Diego to Panama, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
How far ahead should I book a flight from San Diego to Panama?
Booking 75 days in advance of your planned departure date is, on average, the best time to get cheap flights from San Diego to Panama. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
Reviews of airlines servicing Panama
Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated May 20, 2026.
Peruse reviews from past customers who have flown with Delta,Copa Airlines, andUnited Airlines from San Diego to Panama to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.8
Food
7.2
Crew
8.5
Comfort
7.8
Boarding
8.1
Overall
7.9
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Entertainment
7.8
Food
7.2
Crew
8.5
Comfort
7.8
Boarding
8.1
Overall
7.9
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Entertainment
7.8
Food
7.2
Crew
8.5
Comfort
7.8
Boarding
8.1
Overall
7.9
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Entertainment
7.8
Food
7.2
Crew
8.5
Comfort
7.8
Boarding
8.1
Overall
7.9
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Related info for your journey
Find useful and relevant information for your journey from San Diego to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Alternative routes for San Diego to Panama
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Panama by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from San Diego to Panama by cabin class
Find flights from San Diego to Panama, based on your preferred cabin class, be it economy, premium economy, business, or first class.
San Diego and Panama flights
Browse other San Diego and Panama flight options. Last updated on May 20, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from San Diego to Panama
Discover the top 3 airlines that operate flights from San Diego to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 20, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$243 | Average$571 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$285 | Average$403 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$335 | Average$609 | FlexibilityNo cancel fee | On-time70% |