$262+ Cheap flights from San Diego (SAN) to Panama
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/8. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — PTY
Nov 11 — Nov 181
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from San Diego to PanamaExplore the most affordable flight options available from San Diego to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 12, 2026.
Explore the most affordable flight options available from San Diego to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 12, 2026.
This oojo deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/2210:30 pm -
Nonstop6h 06m
Fri 11/271:45 pm -
Nonstop6h 30m
Deal found 10/8![Copa Airlines logo]()
$618
This American Airlines deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/294:40 pm -
2 stops18h 54m
Fri 12/43:13 pm -
2 stops24h 08m
Deal found 10/11![American Airlines logo]()
$637
This American Airlines deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/23:13 pm -
2 stops20h 00m
Wed 12/163:13 pm -
2 stops20h 19m
Deal found 10/9![American Airlines logo]()
$642
This American Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/812:07 pm -
1 stop23h 06m
Fri 12/113:13 pm -
1 stop11h 38m
Deal found 10/8![American Airlines logo]()
$651
This American Airlines deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/157:15 pm -
2 stops15h 58m
Thu 11/263:34 pm -
1 stop22h 29m
Deal found 10/7![American Airlines logo]()
$653
This Copa Airlines deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2810:30 pm -
Nonstop6h 13m
Mon 11/21:45 pm -
Nonstop6h 30m
Deal found 10/7![Copa Airlines logo]()
$660
This oojo deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2010:30 pm -
Nonstop6h 06m
Sun 12/61:45 pm -
Nonstop6h 41m
Deal found 10/12![Copa Airlines logo]()
$663
This American Airlines deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/33:13 pm -
2 stops20h 00m
Mon 12/73:13 pm -
1 stop11h 38m
Deal found 10/10![American Airlines logo]()
$667
This American Airlines deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/1610:40 pm -
1 stop12h 33m
Thu 11/263:34 pm -
1 stop22h 29m
Deal found 10/7![American Airlines logo]()
$668
This United Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/158:05 am -
1 stop8h 33m
Wed 11/258:55 am -
1 stop11h 58m
Deal found 10/8![United Airlines logo]()
$675
This United Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/154:45 pm -
2 stops23h 53m
Tue 11/248:55 am -
1 stop16h 04m
Deal found 10/8![United Airlines logo]()
$680
This United Airlines deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/75:00 pm -
2 stops36h 50m
Sat 11/149:48 am -
2 stops35h 05m
Deal found 10/10![United Airlines logo]()
$1,175
Best flights from San Diego to PanamaDiscover carefully curated flight deals from San Diego to Panama that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 12, 2026.
Discover carefully curated flight deals from San Diego to Panama that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 12, 2026.
This Copa Airlines deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1110:30 pm -
Nonstop6h 06m
Mon 11/161:45 pm -
Nonstop6h 30m
Deal found 10/11![Copa Airlines logo]()
$660
This United Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/28:05 am -
1 stop8h 33m
Tue 11/108:55 am -
1 stop15h 31m
Deal found 10/8![United Airlines logo]()
$675
This Copa Airlines deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/610:30 pm -
Nonstop6h 06m
Sun 11/151:45 pm -
Nonstop6h 30m
Deal found 10/7![Copa Airlines logo]()
$660
This United Airlines deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/158:05 am -
1 stop8h 33m
Tue 11/248:55 am -
1 stop11h 58m
Deal found 10/11![United Airlines logo]()
$675
This United Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/165:00 pm -
1 stop18h 45m
Thu 11/268:55 am -
2 stops26h 41m
Deal found 10/8![United Airlines logo]()
$680
This United Airlines deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/292:30 pm -
2 stops21h 15m
Fri 12/44:41 pm -
3 stops28h 31m
Deal found 10/11![United Airlines logo]()
$680
This United Airlines deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/164:01 pm -
2 stops19h 44m
Tue 11/244:41 pm -
2 stops21h 50m
Deal found 10/7![United Airlines logo]()
$680
This United Airlines deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/282:30 pm -
2 stops26h 08m
Sat 10/313:41 pm -
2 stops25h 06m
Deal found 10/7![United Airlines logo]()
$680
This United Airlines deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/75:00 pm -
1 stop18h 45m
Sat 11/144:41 pm -
1 stop23h 43m
Deal found 10/9![United Airlines logo]()
$689
This United Airlines deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/75:00 pm -
2 stops36h 50m
Sat 11/149:48 am -
2 stops35h 05m
Deal found 10/10![United Airlines logo]()
$1,175
This United Airlines deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/255:00 pm -
2 stops37h 57m
Wed 10/289:45 am -
1 stop10h 42m
Deal found 10/10![United Airlines logo]()
$1,811
Last-minute flights from San Diego to PanamaDiscover last-minute flight deals from San Diego to Panama. Data last updated October 12, 2026 and is based on user searches.
Discover last-minute flight deals from San Diego to Panama. Data last updated October 12, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/219:58 pm -
1 stop13h 04m
Tue 10/272:02 pm -
1 stop11h 01m
Deal found 10/7![American Airlines logo]()
$686
This Copa Airlines deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2810:30 pm -
Nonstop6h 13m
Sat 11/71:45 pm -
Nonstop6h 30m
Deal found 10/7![Copa Airlines logo]()
$660
This American Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/289:58 pm -
1 stop13h 04m
Mon 11/23:13 pm -
1 stop11h 25m
Deal found 10/8![American Airlines logo]()
$683
This United Airlines deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/75:00 pm -
2 stops36h 50m
Sat 11/149:48 am -
2 stops35h 05m
Deal found 10/10![United Airlines logo]()
$1,175
This United Airlines deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/85:00 pm -
1 stop23h 38m
Mon 11/238:55 am -
1 stop16h 04m
Deal found 10/10![United Airlines logo]()
$689
This American Airlines deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/157:15 pm -
2 stops15h 58m
Thu 11/263:34 pm -
1 stop22h 29m
Deal found 10/7![American Airlines logo]()
$653
This United Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/158:05 am -
1 stop8h 33m
Thu 11/268:55 am -
1 stop9h 59m
Deal found 10/8![United Airlines logo]()
$675
This United Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/154:45 pm -
2 stops23h 53m
Tue 11/248:55 am -
1 stop16h 04m
Deal found 10/8![United Airlines logo]()
$680
This American Airlines deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/1610:40 pm -
1 stop12h 33m
Thu 11/263:34 pm -
1 stop22h 29m
Deal found 10/7![American Airlines logo]()
$668
This oojo deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2010:30 pm -
Nonstop6h 06m
Sun 12/61:45 pm -
Nonstop6h 41m
Deal found 10/12![Copa Airlines logo]()
$663
This oojo deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/2210:30 pm -
Nonstop6h 06m
Fri 11/271:45 pm -
Nonstop6h 30m
Deal found 10/8![Copa Airlines logo]()
$618
This American Airlines deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/294:40 pm -
2 stops18h 54m
Fri 12/43:13 pm -
1 stop11h 38m
Deal found 10/11![American Airlines logo]()
$637
One-way flights from San Diego to PanamaSearch for one-way flight options from San Diego to Panama. Find affordable one-way fares based on user searches. Data last updated October 12, 2026.
Search for one-way flight options from San Diego to Panama. Find affordable one-way fares based on user searches. Data last updated October 12, 2026.
This American Airlines deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/810:40 pm -
1 stop11h 46m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/7![American Airlines logo]()
$262
This American Airlines deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/2710:40 pm -
1 stop11h 46m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/11![American Airlines logo]()
$267
This American Airlines deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2612:03 pm -
1 stop23h 31m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/7![American Airlines logo]()
$268
This American Airlines deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/210:40 pm -
1 stop11h 46m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/7![American Airlines logo]()
$277
This American Airlines deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/41:04 pm -
1 stop23h 29m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/7![American Airlines logo]()
$284
This American Airlines deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/312:12 pm -
1 stop24h 43m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/9![American Airlines logo]()
$305
This American Airlines deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/183:24 pm -
2 stops19h 02m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/7![American Airlines logo]()
$306
This American Airlines deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/2810:40 pm -
1 stop14h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/11![American Airlines logo]()
$322
This American Airlines deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/267:15 am -
2 stops27h 11m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/11![American Airlines logo]()
$327
This Kissandfly.com deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kissandfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/112:07 pm -
1 stop24h 23m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/8![British Airways logo]()
$339
This American Airlines deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/249:25 pm -
2 stops15h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/11![American Airlines logo]()
$340
This United Airlines deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/85:18 pm -
2 stops36h 29m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/11![United Airlines logo]()
$959
Find flight deals from San Diego to Panama
Keep the following information in mind while searching for San Diego to Panama flight deals. Data was last updated October 12, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $589 (American Airlines) |
One-way from | $262 (American Airlines) |
Popular in | January |
Cheapest in | February |
Average price | $550 |
Good round-trip deal | $594 or less |
Good one-way deal | $400 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from San Diego to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 12, 2026.
Use the filters below to find and compare flights from San Diego to Panama that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San DiegoPanama City
SAN San Diego - PTY Panama City Tocumen Intl
SANPTY
San Diego
Thu 2/18
12:07 pm-3:30 pm
1 stop24h 23m
Panama City Tocumen Intl
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$284
San DiegoPanama City
SAN San Diego - PTY Panama City Tocumen Intl
SANPTY
San Diego
Wed 3/24
12:07 pm-2:30 pm
1 stop24h 23m
Panama City Tocumen Intl
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$305
San DiegoPanama City
SAN San Diego - PTY Panama City Tocumen Intl
SANPTY
San Diego
Tue 11/24
8:50 am-1:46 pm
3 stops25h 56m
Panama City Tocumen Intl
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$457
San DiegoPanama City
SAN San Diego - PTY Panama City Tocumen Intl
SANPTY
San Diego
Thu 10/29
9:58 pm-1:02 pm
1 stop13h 04m
Panama City Tocumen Intl
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$457
San DiegoPanama City
SAN San Diego - PTY Panama City Tocumen Intl
SANPTY
San Diego
Mon 11/9
6:25 am-7:29 am
3 stops22h 04m
Panama City Tocumen Intl
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$462
San DiegoPanama City
SAN San Diego - PTY Panama City Tocumen Intl
SANPTY
San Diego
Sat 11/14
11:06 am-1:46 pm
3 stops23h 40m
Panama City Tocumen Intl
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$477
San DiegoPanama City
SAN San Diego - PTY Panama City Tocumen Intl
SANPTY
San Diego
Sun 10/18
7:15 pm-1:02 pm
2 stops15h 47m
Panama City Tocumen Intl
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$487
San DiegoPanama City
SAN San Diego - PTY Panama City Tocumen Intl
SANPTY
San Diego
Thu 2/18
3:09 pm-8:29 pm
3 stops26h 20m
Panama City Tocumen Intl
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$521
Quickest round-trip
San DiegoPanama City
SAN San Diego - PTY Panama City Tocumen Intl
SANPTY
San Diego
Sat 11/14
10:40 pm-2:13 pm
1 stop12h 33m
Panama City Tocumen Intl
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$527
San DiegoPanama City
SAN San Diego - PTY Panama City Tocumen Intl
SANPTY
San Diego
Sun 11/15
10:40 pm-2:13 pm
1 stop12h 33m
Panama City Tocumen Intl
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$553
Showing 1-10 of 24 resultsSorted by cheapest first
Best time to book a flight from San Diego to Panama
Have a flexible travel schedule? Discover the best time to fly to Panama from San Diego with our price prediction graph.
SAN-PTY
SAN-DAV
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Diego to Panama
SAN-PA0
SAN-PTY
SAN-DAV
What is the cheapest month to book a flight from San Diego to Panama?
Currently, February is the cheapest month in which you can book a flight from San Diego to Panama (average of $494). Flying from San Diego to Panama in January is currently the most expensive (average of $1,005). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from SAN to PA?
Find hourly flight availability from San Diego to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 12, 2026.
When flying from San Diego to Panama, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
How far ahead should I book a flight from San Diego to Panama?
Booking 90 days in advance of your planned departure date is, on average, the best time to get cheap flights from San Diego to Panama. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
Reviews of airlines servicing Panama
Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated October 12, 2026.
Peruse reviews from past customers who have flown with Copa Airlines,United Airlines, andAmerican Airlines from San Diego to Panama to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
6.9
Overall
7.6
Comfort
7.4
Food
6.9
Crew
8.1
Boarding
7.8
Reviews
1 / 20
2.0
MediocreAnonymous,Oct 2026
BOS - PTY
Entertainment
6.9
Overall
7.6
Comfort
7.4
Food
6.9
Crew
8.1
Boarding
7.8
Reviews
1 / 20
2.0
MediocreAnonymous,Oct 2026
BOS - PTY
Entertainment
6.9
Overall
7.6
Comfort
7.4
Food
6.9
Crew
8.1
Boarding
7.8
Reviews
1 / 20
2.0
MediocreAnonymous,Oct 2026
BOS - PTY
Entertainment
6.9
Overall
7.6
Comfort
7.4
Food
6.9
Crew
8.1
Boarding
7.8
Reviews
1 / 20
2.0
MediocreAnonymous,Oct 2026
BOS - PTY
Related info for your journey
Find useful and relevant information for your journey from San Diego to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for San Diego to Panama
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Complete your trip
Complete your trip to Panama by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from San Diego to Panama by cabin class
Find flights from San Diego to Panama, based on your preferred cabin class, be it economy, premium economy, business, or first class.
San Diego and Panama flights
Browse other San Diego and Panama flight options. Last updated on October 12, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from San Diego to Panama
Discover the top 3 airlines that operate flights from San Diego to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 12, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$279 | Average$708 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$309 | Average$564 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$365 | Average$724 | FlexibilityNo cancel fee | On-time70% |