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San Diego

$379+ Cheap flights from Panama to San Diego (SAN)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/10. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — SAN
Aug 8 — Aug 151
Sat 8/8
Sat 8/15
1 adult, Economy
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Cheap flight deals from Panama to San Diego

Cheapest flights from Panama to San Diego
Explore the most affordable flight options available from Panama to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 9, 2026.

This Copa Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/131:55 pm
PTY
-
SAN
Nonstop6h 35m
Copa Airlines
Fri 9/1810:00 pm
SAN
-
PTY
Nonstop6h 17m
Copa Airlines
Deal found 7/8$736
This United Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/133:30 pm
PTY
-
SAN
1 stop21h 28m
United Airlines
Fri 9/188:00 am
SAN
-
PTY
1 stop8h 37m
United Airlines
Deal found 7/8$741
This United Airlines deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/2610:00 am
PTY
-
SAN
2 stops14h 47m
United Airlines
Thu 9/106:15 am
SAN
-
PTY
2 stops10h 22m
United Airlines
Deal found 7/5$745
This United Airlines deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/110:00 am
PTY
-
SAN
1 stop9h 46m
United Airlines
Mon 10/58:00 am
SAN
-
PTY
1 stop8h 37m
United Airlines
Deal found 7/6$750
This Avianca deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/215:30 am
PTY
-
SAN
2 stops13h 40m
Multiple Airlines
Fri 8/217:59 pm
SAN
-
PTY
2 stops12h 31m
Multiple Airlines
Deal found 7/6$751
This deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1110:00 am
PTY
-
SAN
1 stop13h 24m
United Airlines
Wed 9/238:00 am
SAN
-
PTY
1 stop8h 37m
United Airlines
Deal found 7/5$757
This eDestinos deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/193:50 pm
PTY
-
SAN
2 stops25h 00m
Multiple Airlines
Wed 8/265:00 pm
SAN
-
PTY
2 stops15h 30m
Multiple Airlines
Deal found 7/7$761
This United Airlines deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/203:30 pm
PTY
-
SAN
1 stop21h 25m
United Airlines
Thu 8/278:00 am
SAN
-
PTY
1 stop8h 37m
United Airlines
Deal found 7/5$767
This Avianca deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/185:30 am
PTY
-
SAN
2 stops12h 27m
Multiple Airlines
Tue 8/2510:36 am
SAN
-
PTY
2 stops13h 19m
Multiple Airlines
Deal found 7/4$768
This American Airlines deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/181:39 pm
PTY
-
SAN
1 stop10h 21m
American Airlines
Tue 8/2510:45 pm
SAN
-
PTY
1 stop11h 54m
American Airlines
Deal found 7/4$776

Find flight deals from Panama to San Diego

Keep the following information in mind while searching for Panama to San Diego flight deals. Data was last updated July 9, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$736
(Copa Airlines)

One-way from

$379
(Kiwi.com)

Popular in

June

Cheapest in

October

Average price

$648

Good round-trip deal

$378 or less
Provider with most accurate pricing for Panama City Tocumen Intl-San Diego flight deals.
Search Deals
Provider most trusted by Cheapflights users for Panama City Tocumen Intl-San Diego flights.
Search Deals
From Panama to San Diego
Search Deals
One-way flight from Panama to San Diego
Search Deals
Highest demand for flights based on searches. 20% potential increase in price ($176 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 7% potential price decrease ($48 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in July 2026
Search Deals
Price to beat on a round-trip flight from Panama to San Diego.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 9, 2026.
Use the filters below to find and compare flights from Panama to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

Sun 9/13

1:55 pm-6:30 pm

Nonstop6h 35m

San Diego

Fri 9/18

10:00 pm-6:17 am

Nonstop6h 17m

$736

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

Sun 10/11

10:00 am-9:24 pm

1 stop13h 24m

San Diego

Sat 10/24

12:40 pm-6:38 pm

3 stops27h 58m

$741

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

Sun 9/13

3:30 pm-11:35 am

2 stops22h 05m

San Diego

Fri 9/18

7:41 pm-6:37 pm

2 stops20h 56m

$741

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

Thu 10/1

10:00 am-5:46 pm

1 stop9h 46m

San Diego

Mon 10/5

1:24 pm-2:14 pm

2 stops22h 50m

$755

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

Sat 10/17

3:30 pm-9:05 am

2 stops19h 35m

San Diego

Mon 10/19

2:24 pm-2:14 pm

2 stops21h 50m

$755

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

Thu 8/20

3:30 pm-1:17 pm

1 stop23h 47m

San Diego

Thu 8/27

3:56 pm-2:14 pm

2 stops20h 18m

$767

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

Tue 8/18

1:39 pm-10:00 pm

1 stop10h 21m

San Diego

Tue 8/25

10:45 pm-12:39 pm

1 stop11h 54m

$776
Cheapest one-way
Quickest one-way

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

Wed 12/9

3:30 pm-11:03 pm

1 stop10h 33m

$502

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

Fri 10/9

2:21 pm-11:15 pm

1 stop10h 54m

$529

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/8

Sorted by cheapest first

Best time to book a flight from Panama to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Panama with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama to San Diego

What is the cheapest month to book a flight from Panama to San Diego?

Currently, January is the cheapest month in which you can book a flight from Panama to San Diego (average of $174). Flying from Panama to San Diego in June is currently the most expensive (average of $1,104). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PA to SAN?

Find hourly flight availability from Panama to San Diego. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 9, 2026.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Panama to San Diego as you normally would.

Reviews of airlines servicing San Diego

Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated July 9, 2026.
Peruse reviews from past customers who have flown with Copa Airlines and United Airlines from Panama to San Diego to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.6
Good
1,565 reviews

Crew

8.1

Overall

7.6

Entertainment

6.8

Comfort

7.4

Boarding

7.8

Food

6.9

Reviews

1 / 20
2.0
Mediocre

Maria,Dec 2025

PTY - SLA

Old plain no entertainment , no outlet for cell or computer! And online they said you have all that! Almost 6 hrs looking to the floor..terrible expirencw and I pay a lot of money for it
Copa Airlines
7.6
Good
1,565 reviews
Copa Airlines
7.6
Good
1,565 reviews

Crew

8.1

Overall

7.6

Entertainment

6.8

Comfort

7.4

Boarding

7.8

Food

6.9

Reviews

1 / 20
2.0
Mediocre

Maria,Dec 2025

PTY - SLA

Old plain no entertainment , no outlet for cell or computer! And online they said you have all that! Almost 6 hrs looking to the floor..terrible expirencw and I pay a lot of money for it
United Airlines
7.4
Good
9,955 reviews
Copa Airlines
7.6
Good
1,565 reviews

Crew

8.1

Overall

7.6

Entertainment

6.8

Comfort

7.4

Boarding

7.8

Food

6.9

Reviews

1 / 20
2.0
Mediocre

Maria,Dec 2025

PTY - SLA

Old plain no entertainment , no outlet for cell or computer! And online they said you have all that! Almost 6 hrs looking to the floor..terrible expirencw and I pay a lot of money for it

Related info for your journey

Find useful and relevant information for your journey from Panama to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to San Diego from Panama?

    Most people fly into San Diego (SAN) if they book a flight to San Diego from Panama. San Diego is conveniently located just 2.6 mi from San Diego’s city center.

  • How long is the flight from Panama to San Diego?

    Airlines like Copa Airlines and United Airlines fly from Panama to San Diego in about 6h 35m. The time it takes to get you to your destination can typically vary by up to 6h 49m. Airlines will cover a distance of 2910 mi. This flight may include one or multiple stops.

  • What are the cheapest flights from Panama to San Diego?

    Looking at all options, your cheapest flight can be booked for $378. While the most popular route (Panama City Tocumen Intl - San Diego) can be booked for $736 on average, our data indicates $378 when flying from Panama to San Diego.

  • Can I find deals for flights from Panama to San Diego that include hotel bookings?

    Yes. In addition to deals on Panama to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to San Diego.

  • Can I find deals for business class flights from Panama to San Diego?

    Yes. Cheapflights offers flight deals from Panama to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama to San Diego?

    Currently, January is the cheapest month in which you can book a flight from Panama to San Diego (average of $174). Flying from Panama to San Diego in June is currently the most expensive (average of $1,104). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
El Cajon
National City
Chula Vista
Poway
La Mesa
Coronado
Santee
San Ysidro
Julian
Lemon Grove

Browse thousands of different options on Cheapflights for your next trip

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Top 2 airlines flying from Panama to San Diego

Discover the top 2 airlines that operate flights from Panama to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 9, 2026.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$297Average$642FlexibilityNo cancel feeOn-time70%
United AirlinesCheapest$361Average$722FlexibilityNo cancel feeOn-time69%

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