San Antonio

$330+ Cheap flights from Panama to San Antonio (SAT)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/11. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — SAT
May 15 — May 221
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Cheap flight deals from Panama to San Antonio

Cheapest flights from Panama to San Antonio
Explore the most affordable flight options available from Panama to San Antonio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 15, 2026.

This American Airlines deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/153:40 pm
PTY
-
SAT
1 stop7h 43m
American Airlines
Tue 9/295:27 am
SAT
-
PTY
1 stop8h 43m
American Airlines
Deal found 4/10$622
This United Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/1310:00 am
PTY
-
SAT
1 stop22h 27m
United Airlines
Mon 8/314:13 pm
SAT
-
PTY
1 stop26h 24m
United Airlines
Deal found 4/14$656
This American Airlines deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/291:14 pm
PTY
-
SAT
1 stop10h 45m
American Airlines
Wed 6/36:18 pm
SAT
-
PTY
1 stop17h 56m
American Airlines
Deal found 4/13$661
This American Airlines deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/71:49 pm
PTY
-
SAT
1 stop9h 26m
American Airlines
Thu 6/46:15 pm
SAT
-
PTY
1 stop17h 59m
American Airlines
Deal found 4/11$665
This American Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/291:14 pm
PTY
-
SAT
1 stop10h 45m
American Airlines
Fri 6/56:15 pm
SAT
-
PTY
1 stop17h 59m
American Airlines
Deal found 4/14$675
This American Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/61:49 pm
PTY
-
SAT
1 stop9h 26m
American Airlines
Thu 6/46:15 pm
SAT
-
PTY
1 stop17h 59m
American Airlines
Deal found 4/14$679
This American Airlines deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/232:53 pm
PTY
-
SAT
1 stop27h 45m
American Airlines
Mon 12/285:48 pm
SAT
-
PTY
2 stops19h 05m
American Airlines
Deal found 4/10$682

Find flight deals from Panama to San Antonio

Keep the following information in mind while searching for Panama to San Antonio flight deals. Data was last updated April 15, 2026.

Round-trip from

$622
(American Airlines)

One-way from

$330
(Kiwi.com)

Popular in

March

Cheapest in

April

Average price

$603
From Panama to San Antonio
One-way flight from Panama to San Antonio
Highest demand for flights based on searches. 0% potential increase in price ($6 potential increase over avg. RT price).
Cheapest flight prices on average. 0% potential price decrease ($6 potential savings vs. average RT price).
Average for round-trip flights in April 2026

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama to San Antonio that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 15, 2026.
Use the filters below to find and compare flights from Panama to San Antonio that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Panama CitySan Antonio

PTY - SAT

PTYSAT

Panama City Tocumen Intl

Tue 9/15

3:40 pm-11:23 pm

1 stop7h 43m

San Antonio

Tue 9/29

6:36 pm-2:10 pm

2 stops19h 34m

$626

Panama CitySan Antonio

PTY - SAT

PTYSAT

Panama City Tocumen Intl

Mon 7/13

10:00 am-8:27 am

1 stop22h 27m

San Antonio

Mon 8/31

4:13 pm-6:37 pm

1 stop26h 24m

$656

Panama CitySan Antonio

PTY - SAT

PTYSAT

Panama City Tocumen Intl

Thu 5/7

1:49 pm-11:15 pm

1 stop9h 26m

San Antonio

Thu 6/4

6:15 pm-12:14 pm

1 stop17h 59m

$665

Panama CitySan Antonio

PTY - SAT

PTYSAT

Panama City Tocumen Intl

Fri 5/29

1:14 pm-12:50 pm

2 stops23h 36m

San Antonio

Fri 6/5

5:35 pm-12:14 pm

2 stops18h 39m

$680

Panama CitySan Antonio

PTY - SAT

PTYSAT

Panama City Tocumen Intl

Mon 5/11

3:30 pm-7:40 pm

1 stop28h 10m

San Antonio

Thu 6/4

5:57 pm-6:37 pm

1 stop24h 40m

$699

Panama CitySan Antonio

PTY - SAT

PTYSAT

Panama City Tocumen Intl

Sat 8/15

3:20 pm-11:25 pm

1 stop8h 05m

San Antonio

Sun 9/20

5:27 am-2:10 pm

1 stop8h 43m

$703

Panama CitySan Antonio

PTY - SAT

PTYSAT

Panama City Tocumen Intl

Thu 5/7

10:14 pm-8:55 am

1 stop10h 41m

San Antonio

Thu 6/4

10:16 pm-6:03 am

1 stop7h 47m

$748
Quickest round-trip

Panama CitySan Antonio

PTY - SAT

PTYSAT

Panama City Tocumen Intl

Mon 4/27

3:30 pm-10:59 pm

1 stop7h 29m

San Antonio

Wed 4/29

7:40 am-4:12 pm

1 stop8h 32m

$750
Cheapest one-way

Panama CitySan Antonio

PTY - SAT

PTYSAT

Panama City Tocumen Intl

Mon 5/11

9:33 pm-6:59 pm

3 stops45h 26m

$330
Quickest one-way

Panama CitySan Antonio

PTY - SAT

PTYSAT

Panama City Tocumen Intl

Tue 9/15

3:40 pm-11:23 pm

1 stop7h 43m

$365

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/11

Showing 1-10 of 17 resultsSorted by cheapest first
1
2

Best time to book a flight from Panama to San Antonio

Have a flexible travel schedule? Discover the best time to fly to San Antonio from Panama with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama to San Antonio

What is the cheapest month to book a flight from Panama to San Antonio?

Currently, December is the cheapest month in which you can book a flight from Panama to San Antonio (average of $333). Flying from Panama to San Antonio in March is currently the most expensive (average of $512). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing San Antonio

Get insights into the airlines that provide service to San Antonio. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Antonio. Reviews last updated April 15, 2026.
Read through reviews of airlines operating flights from Panama to San Antonio, such as United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Entertainment

7.1

Overall

7.4

Boarding

7.7

Food

6.6

Comfort

7.3

Crew

8.1

Reviews

1 / 20
6.0
Good

Gerry,Jan 2026

YVR - DEN

Seats were uncomfortable. Second leg of my flight on United had much more comfortable seats

Entertainment

7.1

Overall

7.4

Boarding

7.7

Food

6.6

Comfort

7.3

Crew

8.1

Reviews

1 / 20
6.0
Good

Gerry,Jan 2026

YVR - DEN

Seats were uncomfortable. Second leg of my flight on United had much more comfortable seats

Related info for your journey

Find useful and relevant information for your journey from Panama to San Antonio. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly into for flights to San Antonio from Panama?

    San Antonio (SAT), located 7.6 mi from the city center, is the airport you fly into when you book flights from Panama to San Antonio.

  • How long is the flight from Panama to San Antonio?

    Airlines like American Airlines and United Airlines fly from Panama to San Antonio in about 7h 43m. The time it takes to get you to your destination can typically vary by up to 14h 44m. Airlines will cover a distance of 1876 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Panama to San Antonio that include hotel bookings?

    Yes. In addition to deals on Panama to San Antonio flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama to San Antonio?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to San Antonio.

  • Can I find deals for business class flights from Panama to San Antonio?

    Yes. Cheapflights offers flight deals from Panama to San Antonio by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama to San Antonio?

    Currently, December is the cheapest month in which you can book a flight from Panama to San Antonio (average of $333). Flying from Panama to San Antonio in March is currently the most expensive (average of $512). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Antonio?

Book flights to San Antonio if you plan to visit one of these locations
New Braunfels
Kerrville

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Top airline flying from Panama to San Antonio

Discover the top airline that operate flights from Panama to San Antonio. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 15, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$524Average$666FlexibilityNo cancel feeOn-time69%

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