$330+ Cheap flights from Panama to San Antonio (SAT)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/11. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — SAT
May 15 — May 221
Round-trip
1 adult, Economy
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Find cheap flights from Panama to San Antonio with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Panama to San Antonio
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Best
Last-minute
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Cheapest flights from Panama to San AntonioExplore the most affordable flight options available from Panama to San Antonio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 15, 2026.
Explore the most affordable flight options available from Panama to San Antonio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 15, 2026.
This American Airlines deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/153:40 pm
PTY
- SAT
1 stop7h 43m
American Airlines
Tue 9/295:27 am
SAT
- PTY
1 stop8h 43m
American Airlines
Deal found 4/10![American Airlines logo]()
$622
This United Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/1310:00 am
PTY
- SAT
1 stop22h 27m
United Airlines
Mon 8/314:13 pm
SAT
- PTY
1 stop26h 24m
United Airlines
Deal found 4/14![United Airlines logo]()
$656
This American Airlines deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/291:14 pm
PTY
- SAT
1 stop10h 45m
American Airlines
Wed 6/36:18 pm
SAT
- PTY
1 stop17h 56m
American Airlines
Deal found 4/13![American Airlines logo]()
$661
This American Airlines deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/71:49 pm
PTY
- SAT
1 stop9h 26m
American Airlines
Thu 6/46:15 pm
SAT
- PTY
1 stop17h 59m
American Airlines
Deal found 4/11![American Airlines logo]()
$665
This American Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/291:14 pm
PTY
- SAT
1 stop10h 45m
American Airlines
Fri 6/56:15 pm
SAT
- PTY
1 stop17h 59m
American Airlines
Deal found 4/14![American Airlines logo]()
$675
This American Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/61:49 pm
PTY
- SAT
1 stop9h 26m
American Airlines
Thu 6/46:15 pm
SAT
- PTY
1 stop17h 59m
American Airlines
Deal found 4/14![American Airlines logo]()
$679
This American Airlines deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/232:53 pm
PTY
- SAT
1 stop27h 45m
American Airlines
Mon 12/285:48 pm
SAT
- PTY
2 stops19h 05m
American Airlines
Deal found 4/10![American Airlines logo]()
$682
Best flights from Panama to San AntonioDiscover carefully curated flight deals from Panama to San Antonio that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 15, 2026.
Discover carefully curated flight deals from Panama to San Antonio that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 15, 2026.
This American Airlines deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/153:40 pm
PTY
- SAT
1 stop7h 43m
American Airlines
Tue 9/296:36 pm
SAT
- PTY
2 stops19h 34m
American Airlines
Deal found 4/10![American Airlines logo]()
$626
This United Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/1310:00 am
PTY
- SAT
1 stop22h 27m
United Airlines
Mon 8/314:13 pm
SAT
- PTY
1 stop26h 24m
United Airlines
Deal found 4/14![United Airlines logo]()
$656
This Kiwi.com deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/710:14 pm
PTY
- SAT
1 stop10h 41m
Multiple Airlines
Thu 6/410:16 pm
SAT
- PTY
1 stop7h 47m
Multiple Airlines
Deal found 4/10![Multiple Airlines logo]()
$748
This American Airlines deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/71:49 pm
PTY
- SAT
1 stop9h 26m
American Airlines
Thu 6/46:15 pm
SAT
- PTY
1 stop17h 59m
American Airlines
Deal found 4/11![American Airlines logo]()
$665
This United Airlines deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/113:30 pm
PTY
- SAT
1 stop28h 10m
United Airlines
Thu 6/45:57 pm
SAT
- PTY
1 stop24h 40m
United Airlines
Deal found 4/12![United Airlines logo]()
$699
This American Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/291:14 pm
PTY
- SAT
2 stops23h 36m
American Airlines
Fri 6/55:35 pm
SAT
- PTY
2 stops18h 39m
American Airlines
Deal found 4/14![American Airlines logo]()
$680
This United Airlines deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/273:30 pm
PTY
- SAT
1 stop7h 29m
United Airlines
Wed 4/297:40 am
SAT
- PTY
1 stop8h 32m
United Airlines
Deal found 4/10![United Airlines logo]()
$750
This American Airlines deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/153:20 pm
PTY
- SAT
1 stop8h 05m
American Airlines
Sun 9/205:27 am
SAT
- PTY
1 stop8h 43m
American Airlines
Deal found 4/11![American Airlines logo]()
$703
Last-minute flights from Panama to San AntonioDiscover last-minute flight deals from Panama to San Antonio. Data last updated April 15, 2026 and is based on user searches.
Discover last-minute flight deals from Panama to San Antonio. Data last updated April 15, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/61:49 pm
PTY
- SAT
1 stop9h 26m
American Airlines
Thu 6/46:15 pm
SAT
- PTY
1 stop17h 59m
American Airlines
Deal found 4/14![American Airlines logo]()
$679
This American Airlines deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/71:49 pm
PTY
- SAT
1 stop9h 26m
American Airlines
Thu 6/46:15 pm
SAT
- PTY
1 stop17h 59m
American Airlines
Deal found 4/11![American Airlines logo]()
$665
This United Airlines deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/113:30 pm
PTY
- SAT
1 stop28h 10m
United Airlines
Thu 6/45:57 pm
SAT
- PTY
1 stop24h 40m
United Airlines
Deal found 4/12![United Airlines logo]()
$699
This American Airlines deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/121:49 pm
PTY
- SAT
1 stop9h 26m
American Airlines
Thu 5/285:00 am
SAT
- PTY
1 stop7h 14m
American Airlines
Deal found 4/11![American Airlines logo]()
$703
This American Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/211:14 pm
PTY
- SAT
1 stop10h 45m
American Airlines
Tue 5/2610:53 am
SAT
- PTY
2 stops25h 21m
American Airlines
Deal found 4/14![American Airlines logo]()
$691
This American Airlines deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/291:14 pm
PTY
- SAT
1 stop10h 45m
American Airlines
Wed 6/36:18 pm
SAT
- PTY
1 stop17h 56m
American Airlines
Deal found 4/13![American Airlines logo]()
$661
This American Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/291:14 pm
PTY
- SAT
1 stop10h 45m
American Airlines
Fri 6/56:15 pm
SAT
- PTY
1 stop17h 59m
American Airlines
Deal found 4/14![American Airlines logo]()
$675
One-way flights from Panama to San AntonioSearch for one-way flight options from Panama to San Antonio. Find affordable one-way fares based on user searches. Data last updated April 15, 2026.
Search for one-way flight options from Panama to San Antonio. Find affordable one-way fares based on user searches. Data last updated April 15, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/119:33 pm
PTY
- SAT
3 stops45h 26m
Multiple Airlines
Deal found 4/11![Multiple Airlines logo]()
$330
This American Airlines deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/153:40 pm
PTY
- SAT
1 stop7h 43m
American Airlines
Deal found 4/10![American Airlines logo]()
$365
This Mytrip deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/214:25 am
PTY
- SAT
2 stops28h 40m
Multiple Airlines
Deal found 4/11![Multiple Airlines logo]()
$378
This United Airlines deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/113:30 pm
PTY
- SAT
1 stop26h 15m
United Airlines
Deal found 4/11![United Airlines logo]()
$382
This Kiwi.com deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/309:33 pm
PTY
- SAT
3 stops37h 17m
Multiple Airlines
Deal found 4/12![Multiple Airlines logo]()
$398
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/173:10 pm
PTY
- SAT
3 stops42h 05m
Multiple Airlines
Deal found 4/14![Multiple Airlines logo]()
$400
This United Airlines deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/307:55 am
PTY
- SAT
1 stop24h 32m
United Airlines
Deal found 4/12![United Airlines logo]()
$404
Find flight deals from Panama to San Antonio
Keep the following information in mind while searching for Panama to San Antonio flight deals. Data was last updated April 15, 2026.
Round-trip from | $622 (American Airlines) |
|---|---|
One-way from | $330 (Kiwi.com) |
Popular in | March |
Cheapest in | April |
Average price | $603 |
Cheapflights Fare Finder
Customize your flight search to find flights from Panama to San Antonio that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 15, 2026.
Use the filters below to find and compare flights from Panama to San Antonio that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Panama CitySan Antonio
PTY - SAT
PTYSAT
Panama City Tocumen Intl
Tue 9/15
3:40 pm-11:23 pm
1 stop7h 43m
San Antonio
Tue 9/29
6:36 pm-2:10 pm
2 stops19h 34m
$626
Panama CitySan Antonio
PTY - SAT
PTYSAT
Panama City Tocumen Intl
Mon 7/13
10:00 am-8:27 am
1 stop22h 27m
San Antonio
Mon 8/31
4:13 pm-6:37 pm
1 stop26h 24m
$656
Panama CitySan Antonio
PTY - SAT
PTYSAT
Panama City Tocumen Intl
Thu 5/7
1:49 pm-11:15 pm
1 stop9h 26m
San Antonio
Thu 6/4
6:15 pm-12:14 pm
1 stop17h 59m
$665
Panama CitySan Antonio
PTY - SAT
PTYSAT
Panama City Tocumen Intl
Fri 5/29
1:14 pm-12:50 pm
2 stops23h 36m
San Antonio
Fri 6/5
5:35 pm-12:14 pm
2 stops18h 39m
$680
Panama CitySan Antonio
PTY - SAT
PTYSAT
Panama City Tocumen Intl
Mon 5/11
3:30 pm-7:40 pm
1 stop28h 10m
San Antonio
Thu 6/4
5:57 pm-6:37 pm
1 stop24h 40m
$699
Panama CitySan Antonio
PTY - SAT
PTYSAT
Panama City Tocumen Intl
Sat 8/15
3:20 pm-11:25 pm
1 stop8h 05m
San Antonio
Sun 9/20
5:27 am-2:10 pm
1 stop8h 43m
$703
Panama CitySan Antonio
PTY - SAT
PTYSAT
Panama City Tocumen Intl
Thu 5/7
10:14 pm-8:55 am
1 stop10h 41m
San Antonio
Thu 6/4
10:16 pm-6:03 am
1 stop7h 47m
$748
Quickest round-trip
Panama CitySan Antonio
PTY - SAT
PTYSAT
Panama City Tocumen Intl
Mon 4/27
3:30 pm-10:59 pm
1 stop7h 29m
San Antonio
Wed 4/29
7:40 am-4:12 pm
1 stop8h 32m
$750
Cheapest one-way
Panama CitySan Antonio
PTY - SAT
PTYSAT
Panama City Tocumen Intl
Mon 5/11
9:33 pm-6:59 pm
3 stops45h 26m
$330
Quickest one-way
Panama CitySan Antonio
PTY - SAT
PTYSAT
Panama City Tocumen Intl
Tue 9/15
3:40 pm-11:23 pm
1 stop7h 43m
$365
Showing 1-10 of 17 resultsSorted by cheapest first
Best time to book a flight from Panama to San Antonio
Have a flexible travel schedule? Discover the best time to fly to San Antonio from Panama with our price prediction graph.
PTY-SAT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Panama to San Antonio
PA0-SAT
PTY-SAT
What is the cheapest month to book a flight from Panama to San Antonio?
Currently, December is the cheapest month in which you can book a flight from Panama to San Antonio (average of $333). Flying from Panama to San Antonio in March is currently the most expensive (average of $512). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing San Antonio
Get insights into the airlines that provide service to San Antonio. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Antonio. Reviews last updated April 15, 2026.
Read through reviews of airlines operating flights from Panama to San Antonio, such as United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.1
Overall
7.4
Boarding
7.7
Food
6.6
Comfort
7.3
Crew
8.1
Reviews
1 / 20
6.0
GoodGerry,Jan 2026
YVR - DEN
Entertainment
7.1
Overall
7.4
Boarding
7.7
Food
6.6
Comfort
7.3
Crew
8.1
Reviews
1 / 20
6.0
GoodGerry,Jan 2026
YVR - DEN
Related info for your journey
Find useful and relevant information for your journey from Panama to San Antonio. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Antonio?
Book flights to San Antonio if you plan to visit one of these locationsNew Braunfels
Kerrville
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Complete your trip
Complete your trip to San Antonio by adding a car rental and/or hotel reservation to your travel itinerary.
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Find flights from Panama to San Antonio, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Panama and San Antonio flights
Browse other Panama and San Antonio flight options. Last updated on April 15, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to San Antonio
Explore flights to San Antonio departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on April 15, 2026.
Top airline flying from Panama to San Antonio
Discover the top airline that operate flights from Panama to San Antonio. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 15, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$524 | Average$666 | FlexibilityNo cancel fee | On-time69% |