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$328+ Cheap flights from Panama to Louisville (SDF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/1. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — SDF
May 13 — May 201
Wed 5/13
Wed 5/20
1 adult, Economy
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Cheap flight deals from Panama to Louisville

Cheapest flights from Panama to Louisville
Explore the most affordable flight options available from Panama to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 13, 2026.

This United Airlines deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/1610:00 am
PTY
-
SDF
1 stop9h 00m
United Airlines
Sun 5/2411:13 am
SDF
-
PTY
1 stop9h 18m
United Airlines
Deal found 4/13$603
This United Airlines deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/233:30 pm
PTY
-
SDF
2 stops16h 32m
United Airlines
Tue 6/236:15 am
SDF
-
PTY
1 stop8h 59m
United Airlines
Deal found 4/11$619
This American Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/11:49 pm
PTY
-
SDF
2 stops17h 49m
American Airlines
Sun 5/107:52 pm
SDF
-
PTY
2 stops17h 54m
American Airlines
Deal found 4/8$660
This United Airlines deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/47:55 am
PTY
-
SDF
1 stop13h 04m
United Airlines
Fri 5/86:00 am
SDF
-
PTY
1 stop11h 12m
United Airlines
Deal found 4/9$671
This American Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/271:49 pm
PTY
-
SDF
1 stop9h 10m
American Airlines
Sun 5/107:52 pm
SDF
-
PTY
2 stops17h 54m
American Airlines
Deal found 4/8$692
This American Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/281:49 pm
PTY
-
SDF
1 stop9h 10m
American Airlines
Fri 5/16:06 am
SDF
-
PTY
1 stop7h 40m
American Airlines
Deal found 4/8$708
This United Airlines deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/273:30 pm
PTY
-
SDF
2 stops16h 40m
United Airlines
Sun 5/107:56 pm
SDF
-
PTY
2 stops19h 18m
United Airlines
Deal found 4/10$728
This American Airlines deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/231:14 pm
PTY
-
SDF
2 stops20h 22m
American Airlines
Tue 6/238:05 pm
SDF
-
PTY
2 stops17h 09m
American Airlines
Deal found 4/11$730

Find flight deals from Panama to Louisville

Keep the following information in mind while searching for Panama to Louisville flight deals. Data was last updated April 13, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$603
(United Airlines)

One-way from

$328
(Delta)

Popular in

March

Cheapest in

November

Average price

$647
Provider with most accurate pricing for Panama City Tocumen Intl-Louisville Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Panama City Tocumen Intl-Louisville Intl flights.
Search Deals
From Panama to Louisville Intl
Search Deals
One-way flight from Panama to Louisville Intl
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($70 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($17 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 13, 2026.
Use the filters below to find and compare flights from Panama to Louisville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Sat 5/16

10:00 am-9:59 pm

1 stop10h 59m

Louisville Intl

Sun 5/24

11:13 am-7:31 pm

1 stop9h 18m

$603

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Sat 5/23

3:30 pm-9:02 am

2 stops16h 32m

Louisville Intl

Tue 6/23

6:15 am-2:14 pm

1 stop8h 59m

$619

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Mon 5/4

7:55 am-9:59 pm

1 stop13h 04m

Louisville Intl

Fri 5/8

6:00 am-4:12 pm

1 stop11h 12m

$671
Cheapest one-way
Quickest one-way

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Mon 6/1

2:15 pm-12:25 am

1 stop9h 10m

$328

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Mon 6/1

9:33 pm-11:30 am

3 stops36h 57m

$352

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Sun 5/31

4:25 am-9:28 am

3 stops28h 03m

$381

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Sun 5/31

10:55 pm-10:50 pm

1 stop22h 55m

$406

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/11

Sorted by cheapest first

Best time to book a flight from Panama to Louisville

Have a flexible travel schedule? Discover the best time to fly to Louisville from Panama with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama to Louisville

What is the cheapest month to book a flight from Panama to Louisville?

Currently, October is the cheapest month in which you can book a flight from Panama to Louisville (average of $246). Flying from Panama to Louisville in March is currently the most expensive (average of $751). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Louisville

Get insights into the airlines that provide service to Louisville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Louisville. Reviews last updated April 13, 2026.
Peruse reviews from past customers who have flown with United Airlines from Panama to Louisville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,579 reviews

Overall

7.4

Crew

8.1

Food

6.6

Entertainment

7.1

Boarding

7.7

Comfort

7.3

Reviews

1 / 20
6.0
Good

Gerry,Jan 2026

YVR - DEN

Seats were uncomfortable. Second leg of my flight on United had much more comfortable seats
United Airlines
7.4
Good
9,579 reviews
United Airlines
7.4
Good
9,579 reviews

Overall

7.4

Crew

8.1

Food

6.6

Entertainment

7.1

Boarding

7.7

Comfort

7.3

Reviews

1 / 20
6.0
Good

Gerry,Jan 2026

YVR - DEN

Seats were uncomfortable. Second leg of my flight on United had much more comfortable seats

Related info for your journey

Find useful and relevant information for your journey from Panama to Louisville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Louisville from Panama?

    Located just 5.3 mi from the city center, Louisville Intl (SDF) is the airport most travelers will use when flying to Louisville from Panama.

  • How long is the flight from Panama to Louisville?

    A quick flight from Panama to Louisville can take about 10h 59m. United Airlines provides one of the quickest options available for as low as $603. Panama and Louisville are separated by a distance of 2048 mi.

  • Can I find deals for flights from Panama to Louisville that include hotel bookings?

    Yes. In addition to deals on Panama to Louisville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama to Louisville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to Louisville.

  • Can I find deals for business class flights from Panama to Louisville?

    Yes. Cheapflights offers flight deals from Panama to Louisville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama to Louisville?

    Currently, October is the cheapest month in which you can book a flight from Panama to Louisville (average of $246). Flying from Panama to Louisville in March is currently the most expensive (average of $751). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Louisville?

Book flights to Louisville if you plan to visit one of these locations
Shepherdsville
Elizabethtown
Corydon
Jeffersonville
Bardstown

Browse thousands of different options on Cheapflights for your next trip

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Top airline flying from Panama to Louisville

Discover the top airline that operate flights from Panama to Louisville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 13, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$438Average$660FlexibilityNo cancel feeOn-time69%

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