$416+ Cheap flights from Panama to Louisville (SDF)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/8. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — SDF
Nov 26 — Dec 31
Round-trip
1 adult, Economy
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Find cheap flights from Panama to Louisville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Panama to Louisville
Cheapest
Best
Last-minute
One-way
Cheapest flights from Panama to LouisvilleExplore the most affordable flight options available from Panama to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 27, 2026.
Explore the most affordable flight options available from Panama to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 27, 2026.
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/24:41 pm -
2 stops24h 16m
Sun 11/85:57 pm -
2 stops20h 48m
Deal found 10/22![United Airlines logo]()
$821
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/68:55 am -
1 stop11h 28m
Sun 12/139:10 am -
1 stop29h 35m
Deal found 10/22![United Airlines logo]()
$841
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/14:41 pm -
1 stop29h 17m
Sun 11/82:10 pm -
2 stops24h 35m
Deal found 10/22![United Airlines logo]()
$858
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/203:34 pm -
1 stop8h 49m
Fri 11/276:11 pm -
2 stops20h 23m
Deal found 10/22![American Airlines logo]()
$874
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1012:10 pm -
1 stop23h 38m
Thu 12/179:09 pm -
2 stops47h 10m
Deal found 10/26![Multiple Airlines logo]()
$979
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/93:13 pm -
2 stops18h 09m
Tue 12/156:01 pm -
2 stops20h 12m
Deal found 10/22![American Airlines logo]()
$1,014
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/103:13 pm -
1 stop8h 46m
Thu 12/177:31 pm -
1 stop20h 02m
Deal found 10/26![American Airlines logo]()
$1,030
Best flights from Panama to LouisvilleDiscover carefully curated flight deals from Panama to Louisville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 27, 2026.
Discover carefully curated flight deals from Panama to Louisville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 27, 2026.
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/2611:35 am -
1 stop10h 24m
Fri 1/297:00 am -
1 stop10h 12m
Deal found 10/22![United Airlines logo]()
$714
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/154:41 pm -
1 stop29h 18m
Sat 1/302:03 pm -
1 stop29h 59m
Deal found 10/22![United Airlines logo]()
$744
Last-minute flights from Panama to LouisvilleDiscover last-minute flight deals from Panama to Louisville. Data last updated October 27, 2026 and is based on user searches.
Discover last-minute flight deals from Panama to Louisville. Data last updated October 27, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/14:41 pm -
1 stop29h 17m
Sun 11/82:10 pm -
2 stops24h 35m
Deal found 10/22![United Airlines logo]()
$858
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/24:41 pm -
2 stops24h 16m
Sun 11/85:57 pm -
2 stops20h 48m
Deal found 10/22![United Airlines logo]()
$821
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/203:34 pm -
1 stop8h 49m
Fri 11/276:11 pm -
2 stops20h 23m
Deal found 10/22![American Airlines logo]()
$874
One-way flights from Panama to LouisvilleSearch for one-way flight options from Panama to Louisville. Find affordable one-way fares based on user searches. Data last updated October 27, 2026.
Search for one-way flight options from Panama to Louisville. Find affordable one-way fares based on user searches. Data last updated October 27, 2026.
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/88:00 am -
1 stop12h 51m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/22![Delta logo]()
$416
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/84:55 pm -
2 stops23h 16m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/22![American Airlines logo]()
$549
Find flight deals from Panama to Louisville
Keep the following information in mind while searching for Panama to Louisville flight deals. Data was last updated October 27, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $744 (United Airlines) |
One-way from | $416 (Delta) |
Popular in | January |
Cheapest in | November |
Average price | $827 |
Cheapflights Fare Finder
Customize your flight search to find flights from Panama to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 27, 2026.
Use the filters below to find and compare flights from Panama to Louisville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
Panama CityLouisville
PTY Panama City Tocumen Intl - SDF Louisville Intl
PTYSDF
Panama City Tocumen Intl
Fri 1/8
8:00 am-5:02 pm
1 stop9h 02m
Louisville Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$416
Panama CityLouisville
PTY Panama City Tocumen Intl - SDF Louisville Intl
PTYSDF
Panama City Tocumen Intl
Fri 1/8
4:55 pm-4:11 pm
2 stops23h 16m
Louisville Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$549
Panama CityLouisville
PTY Panama City Tocumen Intl - SDF Louisville Intl
PTYSDF
Panama City Tocumen Intl
Tue 1/26
11:35 am-9:59 pm
1 stop10h 24m
Louisville Intl
Fri 1/29
7:00 am-5:12 pm
1 stop10h 12m
$714
Panama CityLouisville
PTY Panama City Tocumen Intl - SDF Louisville Intl
PTYSDF
Panama City Tocumen Intl
Fri 1/15
4:41 pm-9:59 pm
1 stop29h 18m
Louisville Intl
Sat 1/30
2:03 pm-8:02 pm
1 stop29h 59m
$744
Sorted by cheapest first
Best time to book a flight from Panama to Louisville
Have a flexible travel schedule? Discover the best time to fly to Louisville from Panama with our price prediction graph.
PTY-SDF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Panama to Louisville
PA0-SDF
PTY-SDF
No data available for this route at this time. Please check back soon.
Reviews of airlines servicing Louisville
Get insights into the airlines that provide service to Louisville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Louisville. Reviews last updated October 27, 2026.
Peruse reviews from past customers who have flown with United Airlines from Panama to Louisville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.1
Food
6.7
Comfort
7.3
Crew
8.1
Boarding
7.7
Overall
7.3
Reviews
1 / 20
8.0
ExcellentAsha,Sep 2026
LGA - IAH
Entertainment
7.1
Food
6.7
Comfort
7.3
Crew
8.1
Boarding
7.7
Overall
7.3
Reviews
1 / 20
8.0
ExcellentAsha,Sep 2026
LGA - IAH
Related info for your journey
Find useful and relevant information for your journey from Panama to Louisville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Louisville?
Book flights to Louisville if you plan to visit one of these locationsShepherdsville
Elizabethtown
Jeffersonville
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Complete your trip
Complete your trip to Louisville by adding a car rental and/or hotel reservation to your travel itinerary.
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Find flights from Panama to Louisville, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Louisville
Explore flights to Louisville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 27, 2026.
Panama and Louisville flights
Browse other Panama and Louisville flight options. Last updated on October 27, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from Panama to Louisville
Discover the top airline that operate flights from Panama to Louisville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 27, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$380 | Average$730 | FlexibilityNo cancel fee | On-time69% |