$383+ Cheap flights from Panama to Louisville (SDF)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/13. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — SDF
Oct 12 — Oct 191
Round-trip
1 adult, Economy
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Find cheap flights from Panama to Louisville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Panama to Louisville
Cheapest
Best
Last-minute
One-way
Cheapest flights from Panama to LouisvilleExplore the most affordable flight options available from Panama to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 12, 2026.
Explore the most affordable flight options available from Panama to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 12, 2026.
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/23:24 pm -
1 stop8h 35m
Tue 11/106:00 am -
1 stop8h 02m
Deal found 9/9![Delta logo]()
$624
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/210:00 am -
1 stop10h 39m
Tue 11/101:45 pm -
1 stop30h 17m
Deal found 9/7![United Airlines logo]()
$651
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/143:30 pm -
1 stop29h 40m
Sun 11/151:45 pm -
1 stop30h 17m
Deal found 9/7![United Airlines logo]()
$685
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/294:33 pm -
2 stops21h 51m
Mon 2/157:13 pm -
2 stops20h 01m
Deal found 9/10![American Airlines logo]()
$693
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/13:13 pm -
2 stops19h 24m
Tue 11/106:02 am -
1 stop8h 11m
Deal found 9/8![American Airlines logo]()
$697
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/298:55 am -
1 stop11h 00m
Mon 2/153:50 pm -
1 stop25h 22m
Deal found 9/10![United Airlines logo]()
$699
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/219:45 am -
1 stop9h 28m
Wed 10/281:45 pm -
1 stop30h 17m
Deal found 9/8![United Airlines logo]()
$701
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/13:24 pm -
1 stop8h 35m
Tue 11/107:05 am -
1 stop6h 57m
Deal found 9/8![Delta logo]()
$725
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/149:45 am -
1 stop12h 56m
Sat 11/77:00 am -
1 stop7h 45m
Deal found 9/7![United Airlines logo]()
$732
Best flights from Panama to LouisvilleDiscover carefully curated flight deals from Panama to Louisville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 12, 2026.
Discover carefully curated flight deals from Panama to Louisville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 12, 2026.
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/210:00 am -
1 stop10h 39m
Tue 11/101:45 pm -
1 stop30h 17m
Deal found 9/7![United Airlines logo]()
$651
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/268:55 am -
1 stop10h 40m
Fri 1/297:05 am -
1 stop10h 07m
Deal found 9/7![United Airlines logo]()
$671
Last-minute flights from Panama to LouisvilleDiscover last-minute flight deals from Panama to Louisville. Data last updated September 12, 2026 and is based on user searches.
Discover last-minute flight deals from Panama to Louisville. Data last updated September 12, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/233:30 pm -
1 stop29h 40m
Mon 10/56:30 pm -
1 stop26h 01m
Deal found 9/10![United Airlines logo]()
$746
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/53:30 pm -
2 stops25h 10m
Mon 10/129:40 am -
1 stop9h 57m
Deal found 9/11![United Airlines logo]()
$799
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/143:30 pm -
1 stop29h 40m
Sun 11/151:45 pm -
1 stop30h 17m
Deal found 9/7![United Airlines logo]()
$685
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/149:45 am -
1 stop12h 56m
Sat 11/77:00 am -
1 stop7h 45m
Deal found 9/7![United Airlines logo]()
$732
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/142:02 pm -
2 stops21h 06m
Sat 11/71:32 pm -
2 stops24h 41m
Deal found 9/7![American Airlines logo]()
$737
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/219:45 am -
1 stop9h 28m
Wed 10/281:45 pm -
1 stop30h 17m
Deal found 9/8![United Airlines logo]()
$701
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/219:45 am -
2 stops22h 49m
Tue 10/275:10 am -
2 stops14h 28m
Deal found 9/8![United Airlines logo]()
$778
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/212:02 pm -
1 stop8h 37m
Tue 10/276:00 am -
1 stop8h 02m
Deal found 9/8![American Airlines logo]()
$805
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/223:30 pm -
1 stop29h 40m
Sat 10/3110:55 am -
1 stop9h 07m
Deal found 9/8![United Airlines logo]()
$739
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/232:02 pm -
1 stop8h 37m
Fri 10/306:00 pm -
2 stops20h 02m
Deal found 9/8![American Airlines logo]()
$753
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/259:30 am -
1 stop31h 07m
Sun 11/17:00 am -
1 stop7h 45m
Deal found 9/10![United Airlines logo]()
$768
One-way flights from Panama to LouisvilleSearch for one-way flight options from Panama to Louisville. Find affordable one-way fares based on user searches. Data last updated September 12, 2026.
Search for one-way flight options from Panama to Louisville. Find affordable one-way fares based on user searches. Data last updated September 12, 2026.
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/133:20 pm -
1 stop8h 42m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Delta logo]()
$383
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/132:39 pm -
2 stops22h 13m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![American Airlines logo]()
$392
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/213:30 pm -
2 stops20h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![United Airlines logo]()
$450
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/84:55 pm -
2 stops19h 44m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![American Airlines logo]()
$548
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/84:41 pm -
1 stop28h 49m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![United Airlines logo]()
$557
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/83:20 pm -
1 stop8h 42m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Delta logo]()
$603
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/1311:55 am -
3 stops26h 36m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Multiple Airlines logo]()
$740
Find flight deals from Panama to Louisville
Keep the following information in mind while searching for Panama to Louisville flight deals. Data was last updated September 12, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $624 (Delta) |
One-way from | $383 (Delta) |
Popular in | January |
Cheapest in | November |
Average price | $685 |
Cheapflights Fare Finder
Customize your flight search to find flights from Panama to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 12, 2026.
Use the filters below to find and compare flights from Panama to Louisville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
Panama CityLouisville
PTY Panama City Tocumen Intl - SDF Louisville Intl
PTYSDF
Panama City Tocumen Intl
Sat 2/13
3:20 pm-12:02 am
1 stop8h 42m
Louisville Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$383
Panama CityLouisville
PTY Panama City Tocumen Intl - SDF Louisville Intl
PTYSDF
Panama City Tocumen Intl
Sat 2/13
2:39 pm-12:52 pm
2 stops22h 13m
Louisville Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$392
Panama CityLouisville
PTY Panama City Tocumen Intl - SDF Louisville Intl
PTYSDF
Panama City Tocumen Intl
Wed 10/21
3:30 pm-1:15 pm
2 stops20h 45m
Louisville Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$450
Panama CityLouisville
PTY Panama City Tocumen Intl - SDF Louisville Intl
PTYSDF
Panama City Tocumen Intl
Tue 10/27
3:41 pm-8:33 pm
1 stop27h 52m
Louisville Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$450
Panama CityLouisville
PTY Panama City Tocumen Intl - SDF Louisville Intl
PTYSDF
Panama City Tocumen Intl
Fri 1/8
4:55 pm-12:39 pm
2 stops19h 44m
Louisville Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$548
Panama CityLouisville
PTY Panama City Tocumen Intl - SDF Louisville Intl
PTYSDF
Panama City Tocumen Intl
Fri 1/8
4:41 pm-9:30 pm
1 stop28h 49m
Louisville Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$557
Panama CityLouisville
PTY Panama City Tocumen Intl - SDF Louisville Intl
PTYSDF
Panama City Tocumen Intl
Fri 1/8
3:20 pm-12:02 am
1 stop8h 42m
Louisville Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$603
Panama CityLouisville
PTY Panama City Tocumen Intl - SDF Louisville Intl
PTYSDF
Panama City Tocumen Intl
Mon 11/2
10:00 am-8:39 pm
1 stop10h 39m
Louisville Intl
Tue 11/10
1:45 pm-8:02 pm
1 stop30h 17m
$651
Panama CityLouisville
PTY Panama City Tocumen Intl - SDF Louisville Intl
PTYSDF
Panama City Tocumen Intl
Tue 1/26
8:55 am-7:35 pm
1 stop10h 40m
Louisville Intl
Fri 1/29
7:05 am-5:12 pm
1 stop10h 07m
$671
Panama CityLouisville
PTY Panama City Tocumen Intl - SDF Louisville Intl
PTYSDF
Panama City Tocumen Intl
Sat 2/13
11:55 am-2:31 pm
3 stops26h 36m
Louisville Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$740
Sorted by cheapest first
Best time to book a flight from Panama to Louisville
Have a flexible travel schedule? Discover the best time to fly to Louisville from Panama with our price prediction graph.
PTY-SDF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Panama to Louisville
PA0-SDF
PTY-SDF
No data available for this route at this time. Please check back soon.
Reviews of airlines servicing Louisville
Get insights into the airlines that provide service to Louisville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Louisville. Reviews last updated September 12, 2026.
Peruse reviews from past customers who have flown with United Airlines from Panama to Louisville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
6.7
Boarding
7.7
Comfort
7.3
Crew
8.1
Overall
7.4
Entertainment
7.1
Reviews
1 / 20
4.0
OkayChris,Aug 2026
MIA - ORD
Food
6.7
Boarding
7.7
Comfort
7.3
Crew
8.1
Overall
7.4
Entertainment
7.1
Reviews
1 / 20
4.0
OkayChris,Aug 2026
MIA - ORD
Related info for your journey
Find useful and relevant information for your journey from Panama to Louisville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Louisville?
Book flights to Louisville if you plan to visit one of these locationsShepherdsville
Elizabethtown
Jeffersonville
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Complete your trip
Complete your trip to Louisville by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Panama to Louisville by cabin class
Find flights from Panama to Louisville, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Louisville
Explore flights to Louisville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 12, 2026.
Panama and Louisville flights
Browse other Panama and Louisville flight options. Last updated on September 12, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from Panama to Louisville
Discover the top airline that operate flights from Panama to Louisville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 12, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$380 | Average$730 | FlexibilityNo cancel fee | On-time69% |