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$376+ Cheap flights from Panama to Louisville (SDF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/16. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — SDF
Aug 22 — Aug 291
Sat 8/22
Sat 8/29
1 adult, Economy
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Cheap flight deals from Panama to Louisville

Cheapest flights from Panama to Louisville
Explore the most affordable flight options available from Panama to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 23, 2026.

This United Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/287:55 am
PTY
-
SDF
1 stop13h 03m
United Airlines
Wed 11/116:12 pm
SDF
-
PTY
2 stops25h 50m
United Airlines
Deal found 7/21$686
This United Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/410:55 pm
PTY
-
SDF
1 stop12h 27m
United Airlines
Fri 9/117:25 am
SDF
-
PTY
1 stop12h 12m
United Airlines
Deal found 7/21$688
This United Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/1510:00 am
PTY
-
SDF
2 stops22h 57m
United Airlines
Tue 9/225:15 am
SDF
-
PTY
2 stops14h 22m
United Airlines
Deal found 7/22$699
This United Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/33:30 pm
PTY
-
SDF
2 stops20h 41m
United Airlines
Thu 9/107:25 am
SDF
-
PTY
1 stop7h 49m
United Airlines
Deal found 7/20$708
This American Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/161:16 pm
PTY
-
SDF
2 stops19h 27m
American Airlines
Mon 9/217:27 pm
SDF
-
PTY
2 stops17h 59m
American Airlines
Deal found 7/21$712
This American Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/301:52 pm
PTY
-
SDF
1 stop8h 57m
American Airlines
Thu 11/56:31 pm
SDF
-
PTY
2 stops19h 42m
American Airlines
Deal found 7/22$713
This United Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/110:00 am
PTY
-
SDF
2 stops22h 38m
United Airlines
Wed 9/99:00 am
SDF
-
PTY
2 stops11h 31m
United Airlines
Deal found 7/20$722
This United Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/119:45 am
PTY
-
SDF
1 stop12h 14m
United Airlines
Sat 9/127:25 am
SDF
-
PTY
1 stop7h 49m
United Airlines
Deal found 7/20$730
This United Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/307:55 am
PTY
-
SDF
3 stops35h 46m
United Airlines
Thu 11/51:47 pm
SDF
-
PTY
2 stops24h 58m
United Airlines
Deal found 7/22$738
This United Airlines deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1010:00 am
PTY
-
SDF
1 stop9h 01m
United Airlines
Sun 8/169:45 am
SDF
-
PTY
1 stop9h 52m
United Airlines
Deal found 7/19$741

Find flight deals from Panama to Louisville

Keep the following information in mind while searching for Panama to Louisville flight deals. Data was last updated July 23, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$686
(United Airlines)

One-way from

$376
(United Airlines)

Popular in

January

Cheapest in

November

Average price

$704
Provider with most accurate pricing for Panama City Tocumen Intl-Louisville Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Panama City Tocumen Intl-Louisville Intl flights.
Search Deals
From Panama to Louisville Intl
Search Deals
One-way flight from Panama to Louisville Intl
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($84 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($28 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in July 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 23, 2026.
Use the filters below to find and compare flights from Panama to Louisville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Fri 10/30

2:21 pm-10:35 pm

1 stop7h 14m

Louisville Intl

Thu 11/5

7:00 am-1:56 pm

1 stop6h 56m

$686

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Wed 10/28

7:55 am-9:43 am

3 stops24h 48m

Louisville Intl

Wed 11/11

6:12 pm-8:02 pm

2 stops25h 50m

$686

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Tue 9/15

2:23 pm-11:59 pm

1 stop8h 36m

Louisville Intl

Tue 9/22

7:05 am-12:58 pm

1 stop6h 53m

$686

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Tue 9/15

10:00 am-9:57 am

2 stops22h 57m

Louisville Intl

Tue 9/22

5:15 am-6:37 pm

2 stops14h 22m

$699

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Thu 9/3

3:30 pm-1:11 pm

2 stops20h 41m

Louisville Intl

Thu 9/10

9:00 am-7:31 pm

2 stops11h 31m

$708

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Tue 9/1

2:20 pm-12:34 am

1 stop9h 14m

Louisville Intl

Wed 9/9

6:00 am-12:58 pm

1 stop7h 58m

$708

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Wed 9/16

1:16 pm-10:42 pm

1 stop8h 26m

Louisville Intl

Mon 9/21

7:27 pm-12:26 pm

2 stops17h 59m

$712

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Tue 9/1

3:30 pm-1:11 pm

2 stops20h 41m

Louisville Intl

Wed 9/9

9:45 am-6:37 pm

1 stop9h 52m

$722
Cheapest one-way

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Mon 11/16

8:55 am-7:01 pm

3 stops34h 06m

$376
Quickest one-way

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Sun 11/15

4:41 pm-9:43 am

2 stops17h 02m

$382

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/20

Showing 1-10 of 16 resultsSorted by cheapest first
1
2

Best time to book a flight from Panama to Louisville

Have a flexible travel schedule? Discover the best time to fly to Louisville from Panama with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama to Louisville

What is the cheapest month to book a flight from Panama to Louisville?

Currently, November is the cheapest month in which you can book a flight from Panama to Louisville (average of $451). Flying from Panama to Louisville in January is currently the most expensive (average of $1,014). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Louisville

Get insights into the airlines that provide service to Louisville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Louisville. Reviews last updated July 23, 2026.
Peruse reviews from past customers who have flown with United Airlines from Panama to Louisville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
10,027 reviews

Overall

7.4

Entertainment

7.1

Comfort

7.3

Crew

8.1

Food

6.6

Boarding

7.7

Reviews

1 / 20
6.0
Good

ROHIT,Jun 2026

IND - EWR

It should not be delayed by 2 hours. I missed the important event due to this
United Airlines
7.4
Good
10,027 reviews
United Airlines
7.4
Good
10,027 reviews

Overall

7.4

Entertainment

7.1

Comfort

7.3

Crew

8.1

Food

6.6

Boarding

7.7

Reviews

1 / 20
6.0
Good

ROHIT,Jun 2026

IND - EWR

It should not be delayed by 2 hours. I missed the important event due to this

Related info for your journey

Find useful and relevant information for your journey from Panama to Louisville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Louisville from Panama?

    Located just 5.3 mi from the city center, Louisville Intl (SDF) is the airport most travelers will use when flying to Louisville from Panama.

  • How long is the flight from Panama to Louisville?

    A quick flight from Panama to Louisville can take about 7h 14m. Delta provides one of the quickest options available for as low as $686. Panama and Louisville are separated by a distance of 2048 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Panama to Louisville that include hotel bookings?

    Yes. In addition to deals on Panama to Louisville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama to Louisville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to Louisville.

  • Can I find deals for business class flights from Panama to Louisville?

    Yes. Cheapflights offers flight deals from Panama to Louisville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama to Louisville?

    Currently, November is the cheapest month in which you can book a flight from Panama to Louisville (average of $451). Flying from Panama to Louisville in January is currently the most expensive (average of $1,014). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Louisville?

Book flights to Louisville if you plan to visit one of these locations
Corydon
Shepherdsville
Elizabethtown
Jeffersonville
Bardstown

Browse thousands of different options on Cheapflights for your next trip

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Top airline flying from Panama to Louisville

Discover the top airline that operate flights from Panama to Louisville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 23, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$451Average$730FlexibilityNo cancel feeOn-time69%

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