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$342+ Cheap flights from Panama to Louisville (SDF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/7. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — SDF
jul. 5 — jul. 121
dom. 7/5
dom. 7/12
1 adult, Economy
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Cheap flight deals from Panama to Louisville

Cheapest flights from Panama to Louisville
Explore the most affordable flight options available from Panama to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on junio 5, 2026.

This United Airlines deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 8/1010:55 pm
PTY
-
SDF
2 stops19h 12m
United Airlines
lun. 8/247:25 am
SDF
-
PTY
1 stop12h 12m
United Airlines
Deal found 5/31$622
This United Airlines deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 8/193:30 pm
PTY
-
SDF
2 stops20h 41m
United Airlines
dom. 8/236:15 am
SDF
-
PTY
1 stop14h 16m
United Airlines
Deal found 6/1$635
This United Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 7/3010:55 pm
PTY
-
SDF
2 stops19h 01m
United Airlines
dom. 8/307:25 am
SDF
-
PTY
1 stop7h 49m
United Airlines
Deal found 6/4$643
This United Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 11/134:41 pm
PTY
-
SDF
2 stops24h 08m
United Airlines
mar. 11/175:35 am
SDF
-
PTY
2 stops14h 27m
United Airlines
Deal found 6/4$667
This United Airlines deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 7/610:00 am
PTY
-
SDF
2 stops22h 26m
United Airlines
vie. 7/177:55 pm
SDF
-
PTY
2 stops21h 17m
United Airlines
Deal found 6/1$673
This United Airlines deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 6/267:55 am
PTY
-
SDF
2 stops15h 04m
United Airlines
jue. 7/27:55 pm
SDF
-
PTY
2 stops19h 19m
United Airlines
Deal found 6/3$737

Find flight deals from Panama to Louisville

Keep the following information in mind while searching for Panama to Louisville flight deals. Data was last updated junio 5, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$622
(United Airlines)

One-way from

$342
(Kiwi.com)

Popular in

June

Cheapest in

November

Average price

$1,010
Provider with most accurate pricing for Panama City Tocumen Intl-Louisville Intl flight deals.
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Provider most trusted by Cheapflights users for Panama City Tocumen Intl-Louisville Intl flights.
Search Deals
From Panama to Louisville Intl
Search Deals
One-way flight from Panama to Louisville Intl
Search Deals
Highest demand for flights based on searches. 6% potential increase in price ($48 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($32 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in June 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated junio 5, 2026.
Use the filters below to find and compare flights from Panama to Louisville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

lun. 8/10

10:55 pm-4:37 pm

2 stops16h 42m

Louisville Intl

lun. 8/24

7:10 am-6:37 pm

2 stops12h 27m

$622

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

mié. 8/19

3:30 pm-1:11 pm

2 stops20h 41m

Louisville Intl

dom. 8/23

6:15 am-7:31 pm

1 stop14h 16m

$635

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

jue. 7/30

10:00 am-10:15 pm

1 stop11h 15m

Louisville Intl

dom. 8/30

6:15 am-4:04 am

1 stop22h 49m

$643

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

dom. 7/19

10:55 pm-10:50 pm

1 stop22h 55m

Louisville Intl

dom. 7/26

7:55 pm-4:12 pm

2 stops21h 17m

$656

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

vie. 11/13

4:41 pm-4:49 pm

2 stops24h 08m

Louisville Intl

mar. 11/17

8:45 am-8:02 pm

1 stop11h 17m

$667

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

lun. 7/6

10:55 pm-6:56 pm

2 stops19h 01m

Louisville Intl

vie. 7/17

6:30 am-4:04 am

1 stop22h 34m

$673
Cheapest one-way

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

lun. 10/12

9:45 am-8:20 pm

1 stop9h 35m

$348
Quickest one-way

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

mar. 7/7

2:24 pm-12:26 am

1 stop9h 02m

$388

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

sáb. 6/13

10:00 am-10:15 pm

1 stop11h 15m

$490

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

sáb. 6/13

4:25 am-8:46 am

3 stops51h 21m

$506

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/2

Sorted by cheapest first

Best time to book a flight from Panama to Louisville

Have a flexible travel schedule? Discover the best time to fly to Louisville from Panama with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama to Louisville

What is the cheapest month to book a flight from Panama to Louisville?

Currently, May is the cheapest month in which you can book a flight from Panama to Louisville (average of $257). Flying from Panama to Louisville in March is currently the most expensive (average of $797). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Louisville

Get insights into the airlines that provide service to Louisville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Louisville. Reviews last updated junio 5, 2026.
Peruse reviews from past customers who have flown with United Airlines from Panama to Louisville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,775 reviews

Comfort

7.3

Crew

8.1

Entertainment

7.1

Food

6.6

Boarding

7.7

Overall

7.4

Reviews

1 / 20
4.0
Okay

Dynasty,May 2026

LAX - EWR

The food wasn’t nice - Hosts were not that kind.
United Airlines
7.4
Good
9,775 reviews
United Airlines
7.4
Good
9,775 reviews

Comfort

7.3

Crew

8.1

Entertainment

7.1

Food

6.6

Boarding

7.7

Overall

7.4

Reviews

1 / 20
4.0
Okay

Dynasty,May 2026

LAX - EWR

The food wasn’t nice - Hosts were not that kind.

Related info for your journey

Find useful and relevant information for your journey from Panama to Louisville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Louisville from Panama?

    Located just 5.3 mi from the city center, Louisville Intl (SDF) is the airport most travelers will use when flying to Louisville from Panama.

  • How long is the flight from Panama to Louisville?

    A quick flight from Panama to Louisville can take about 20h 41m. United Airlines provides one of the quickest options available for as low as $635. Panama and Louisville are separated by a distance of 2048 mi.

  • Can I find deals for flights from Panama to Louisville that include hotel bookings?

    Yes. In addition to deals on Panama to Louisville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama to Louisville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to Louisville.

  • Can I find deals for business class flights from Panama to Louisville?

    Yes. Cheapflights offers flight deals from Panama to Louisville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama to Louisville?

    Currently, May is the cheapest month in which you can book a flight from Panama to Louisville (average of $257). Flying from Panama to Louisville in March is currently the most expensive (average of $797). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Louisville?

Book flights to Louisville if you plan to visit one of these locations
Corydon
Shepherdsville
Elizabethtown
Jeffersonville
Bardstown

Browse thousands of different options on Cheapflights for your next trip

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Top airline flying from Panama to Louisville

Discover the top airline that operate flights from Panama to Louisville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated junio 5, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$451Average$730FlexibilityNo cancel feeOn-time69%

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