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$328+ Cheap flights from Panama City (PTY) to Louisville (SDF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/30. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — SDF
May 30 — Jun 61
Sat 5/30
Sat 6/6
1 adult, Economy
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Cheap flight deals from Panama City to Louisville

Cheapest flights from Panama City to Louisville
Explore the most affordable flight options available from Panama City to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 30, 2026.

This United Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/53:30 pm
PTY
-
SDF
2 stops20h 31m
United Airlines
Sun 9/137:10 am
SDF
-
PTY
1 stop8h 04m
United Airlines
Deal found 4/26$589
This American Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/102:50 pm
PTY
-
SDF
1 stop9h 04m
American Airlines
Tue 12/156:23 pm
SDF
-
PTY
2 stops21h 14m
American Airlines
Deal found 4/26$618
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/203:30 pm
PTY
-
SDF
2 stops16h 32m
United Airlines
Tue 8/1110:15 am
SDF
-
PTY
2 stops18h 49m
United Airlines
Deal found 4/29$644
This American Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/161:49 pm
PTY
-
SDF
1 stop9h 10m
American Airlines
Sun 5/248:08 pm
SDF
-
PTY
2 stops17h 06m
American Airlines
Deal found 4/26$692
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/113:30 pm
PTY
-
SDF
1 stop29h 29m
United Airlines
Mon 10/53:50 pm
SDF
-
PTY
1 stop23h 24m
United Airlines
Deal found 4/28$693
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/72:50 pm
PTY
-
SDF
1 stop9h 04m
American Airlines
Sat 12/126:00 am
SDF
-
PTY
1 stop7h 48m
American Airlines
Deal found 4/27$695
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/1410:55 pm
PTY
-
SDF
1 stop22h 55m
United Airlines
Sun 6/216:15 am
SDF
-
PTY
1 stop10h 57m
United Airlines
Deal found 4/29$709
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/202:27 pm
PTY
-
SDF
1 stop8h 54m
Delta
Tue 8/117:00 am
SDF
-
PTY
1 stop7h 13m
Delta
Deal found 4/29$764

Find flight deals from Panama City to Louisville

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Louisville (SDF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 30, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$589
(United Airlines)

One-way from

$328
(United Airlines)

Popular in

March

Cheapest in

November

Average price

$647
Provider with most accurate pricing for Panama City Tocumen Intl-Louisville Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Panama City Tocumen Intl-Louisville Intl flights.
Search Deals
From Panama City Tocumen Intl to Louisville Intl
Search Deals
One-way flight from Panama City Tocumen Intl to Louisville Intl
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($70 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($17 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2026.
Use the filters below to find and compare flights from Panama City to Louisville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Sat 9/5

3:30 pm-1:01 pm

2 stops20h 31m

Louisville Intl

Sun 9/13

7:10 am-2:14 pm

1 stop8h 04m

$589

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Sat 6/20

3:30 pm-9:02 am

2 stops16h 32m

Louisville Intl

Tue 8/11

10:15 am-4:04 am

2 stops18h 49m

$644

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Sat 5/16

1:49 pm-8:38 am

2 stops17h 49m

Louisville Intl

Sun 5/24

7:05 pm-12:14 pm

2 stops18h 09m

$692
Quickest round-trip

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Sat 5/16

7:55 am-8:00 pm

1 stop11h 05m

Louisville Intl

Sun 5/24

11:13 am-7:31 pm

1 stop9h 18m

$693

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Mon 5/11

3:30 pm-12:00 pm

1 stop19h 30m

Louisville Intl

Mon 10/5

6:00 pm-2:14 pm

2 stops21h 14m

$693

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Sun 6/14

10:55 pm-10:50 pm

1 stop22h 55m

Louisville Intl

Sun 6/21

6:15 am-4:12 pm

1 stop10h 57m

$709
Cheapest one-way

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Tue 6/30

7:55 am-8:01 pm

1 stop11h 06m

$328
Quickest one-way

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Mon 6/29

2:24 pm-12:32 am

1 stop9h 08m

$328

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Sat 6/27

9:45 am-10:50 pm

1 stop12h 05m

$328

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Sat 9/26

3:30 pm-7:35 pm

1 stop27h 05m

$328

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/26

Showing 1-10 of 11 resultsSorted by cheapest first
1
2
  • Most accurate provider: When it comes to deals on Panama City-Louisville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City-Louisville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City-Louisville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Panama City-Louisville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City-Louisville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Panama City to Louisville

Have a flexible travel schedule? Discover the best time to fly to Louisville from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Louisville

What is the cheapest month to book a flight from Panama City to Louisville?

Currently, November is the cheapest month in which you can book a flight from Panama City to Louisville (average of $451). Flying from Panama City to Louisville in March is currently the most expensive (average of $797). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Panama City to Louisville?

Reviews of airlines servicing Louisville

Get insights into the airlines that provide service to Louisville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Louisville. Reviews last updated April 30, 2026.
Peruse reviews from past customers who have flown with United Airlines from Panama City to Louisville to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,677 reviews

Comfort

7.3

Food

6.6

Entertainment

7.1

Boarding

7.7

Crew

8.1

Overall

7.4

Reviews

1 / 20
8.0
Excellent

Anonymous,Apr 2026

DFW - EWR

The flight was on time. Crew was friendly. Will fly again. The seats was comfortable.
United Airlines
7.4
Good
9,677 reviews
United Airlines
7.4
Good
9,677 reviews

Comfort

7.3

Food

6.6

Entertainment

7.1

Boarding

7.7

Crew

8.1

Overall

7.4

Reviews

1 / 20
8.0
Excellent

Anonymous,Apr 2026

DFW - EWR

The flight was on time. Crew was friendly. Will fly again. The seats was comfortable.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Louisville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Panama City to Louisville?

    For as low as $692, United Airlines can have you in Louisville from Panama City in 17h 49m. There are 2048 mi between Panama City and Louisville. Both multi-stop and nonstop flights can be found to your destination and back.

  • What is the cheapest airline to fly from Panama City to Louisville round-trip?

    Flying on United Airlines is currently your cheapest option to Louisville, with prices starting at $438. You may be able to fly from Panama City to Louisville for 29% less than the average price by searching for this airline.

  • Can I find deals for flights from Panama City to Louisville that include hotel bookings?

    Yes. In addition to deals on Panama City to Louisville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Louisville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Louisville.

  • Can I find deals for business class flights from Panama City to Louisville?

    Yes. Cheapflights offers flight deals from Panama City to Louisville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Louisville?

    Currently, November is the cheapest month in which you can book a flight from Panama City to Louisville (average of $451). Flying from Panama City to Louisville in March is currently the most expensive (average of $797). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Louisville?

Book flights to Louisville if you plan to visit one of these locations
Shepherdsville
Elizabethtown
Corydon
Jeffersonville
Bardstown

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Alternative routes for Panama City to Louisville

See prices for flight routes from nearby airports that may be better suited for you.
Panama City to Cincinnati flights
Panama City to Nashville flights

Top airline flying from Panama City to Louisville

Discover the top airline that operate flights from Panama City to Louisville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$438Average$660FlexibilityNo cancel feeOn-time69%

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