$416+ Cheap flights from Panama City (PTY) to Louisville (SDF)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/8. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — SDF
Nov 29 — Dec 61
Round-trip
1 adult, Economy
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Find cheap flights from Panama City to Louisville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Panama City to Louisville
Cheapest
Best
Last-minute
One-way
Cheapest flights from Panama City to LouisvilleExplore the most affordable flight options available from Panama City to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2026.
Explore the most affordable flight options available from Panama City to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2026.
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/98:55 am -
1 stop11h 28m
Mon 12/147:05 am -
1 stop7h 40m
Deal found 10/25![United Airlines logo]()
$821
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/28:55 am -
1 stop13h 03m
Sun 11/83:45 pm -
1 stop27h 53m
Deal found 10/28![United Airlines logo]()
$842
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/14:41 pm -
1 stop29h 17m
Sun 11/83:45 pm -
1 stop27h 53m
Deal found 10/28![United Airlines logo]()
$850
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/911:35 am -
1 stop10h 24m
Tue 12/157:05 am -
1 stop12h 33m
Deal found 10/30![United Airlines logo]()
$889
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/93:13 pm -
1 stop8h 46m
Tue 12/1512:12 pm -
2 stops26h 01m
Deal found 10/27![American Airlines logo]()
$970
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1012:10 pm -
1 stop23h 38m
Thu 12/179:09 pm -
2 stops47h 10m
Deal found 10/26![Multiple Airlines logo]()
$979
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/103:13 pm -
1 stop8h 46m
Thu 12/177:31 pm -
1 stop20h 02m
Deal found 10/26![American Airlines logo]()
$1,030
Best flights from Panama City to LouisvilleDiscover carefully curated flight deals from Panama City to Louisville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 30, 2026.
Discover carefully curated flight deals from Panama City to Louisville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 30, 2026.
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/174:41 pm -
1 stop29h 18m
Mon 1/257:00 am -
2 stops12h 38m
Deal found 10/27![United Airlines logo]()
$727
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/268:55 am -
1 stop11h 24m
Fri 1/299:10 am -
1 stop8h 02m
Deal found 10/29![United Airlines logo]()
$736
Last-minute flights from Panama City to LouisvilleDiscover last-minute flight deals from Panama City to Louisville. Data last updated October 30, 2026 and is based on user searches.
Discover last-minute flight deals from Panama City to Louisville. Data last updated October 30, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/14:41 pm -
1 stop29h 17m
Sun 11/83:45 pm -
1 stop27h 53m
Deal found 10/28![United Airlines logo]()
$850
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/28:55 am -
1 stop13h 03m
Sun 11/83:45 pm -
1 stop27h 53m
Deal found 10/28![United Airlines logo]()
$842
This KAYAK deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/294:41 pm -
1 stop29h 17m
Sun 12/62:05 pm -
1 stop29h 57m
Deal found 10/30![Copa Airlines logo]()
$1,165
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/2912:03 pm -
1 stop29h 51m
Sun 12/69:09 pm -
2 stops23h 10m
Deal found 10/30![Multiple Airlines logo]()
$1,180
This American Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/293:34 pm -
2 stops19h 01m
Sun 12/66:03 am -
1 stop8h 10m
Deal found 10/30![American Airlines logo]()
$1,228
One-way flights from Panama City to LouisvilleSearch for one-way flight options from Panama City to Louisville. Find affordable one-way fares based on user searches. Data last updated October 30, 2026.
Search for one-way flight options from Panama City to Louisville. Find affordable one-way fares based on user searches. Data last updated October 30, 2026.
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/88:00 am -
1 stop9h 02m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/29![Delta logo]()
$416
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/84:55 pm -
2 stops19h 31m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/28![American Airlines logo]()
$549
Find flight deals from Panama City to Louisville
Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Louisville (SDF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 30, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $727 (United Airlines) |
One-way from | $416 (Delta) |
Popular in | January |
Cheapest in | November |
Average price | $827 |
Cheapflights Fare Finder
Customize your flight search to find flights from Panama City to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 30, 2026.
Use the filters below to find and compare flights from Panama City to Louisville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
Panama CityLouisville
PTY Panama City Tocumen Intl - SDF Louisville Intl
PTYSDF
Panama City Tocumen Intl
Fri 1/8
8:00 am-5:02 pm
1 stop9h 02m
Louisville Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$416
Panama CityLouisville
PTY Panama City Tocumen Intl - SDF Louisville Intl
PTYSDF
Panama City Tocumen Intl
Fri 1/8
4:55 pm-12:26 pm
2 stops19h 31m
Louisville Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$549
Panama CityLouisville
PTY Panama City Tocumen Intl - SDF Louisville Intl
PTYSDF
Panama City Tocumen Intl
Sun 1/17
4:41 pm-9:59 pm
1 stop29h 18m
Louisville Intl
Mon 1/25
7:00 am-7:38 pm
2 stops12h 38m
$727
Panama CityLouisville
PTY Panama City Tocumen Intl - SDF Louisville Intl
PTYSDF
Panama City Tocumen Intl
Tue 1/26
8:55 am-8:19 pm
1 stop11h 24m
Louisville Intl
Fri 1/29
9:10 am-5:12 pm
1 stop8h 02m
$736
Sorted by cheapest first
Compare providers for flights from Panama City to Louisville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to Louisville in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Panama City-Louisville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City-Louisville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City-Louisville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Panama City-Louisville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City-Louisville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Panama City to Louisville
Have a flexible travel schedule? Discover the best time to fly to Louisville from Panama City with our price prediction graph.
PTY-SDF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Louisville
Get insights into the airlines that provide service to Louisville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Louisville. Reviews last updated October 30, 2026.
Peruse reviews from past customers who have flown with United Airlines from Panama City to Louisville to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.1
Entertainment
7.1
Comfort
7.3
Overall
7.3
Boarding
7.7
Food
6.7
Reviews
1 / 20
8.0
ExcellentAsha,Sep 2026
LGA - IAH
Crew
8.1
Entertainment
7.1
Comfort
7.3
Overall
7.3
Boarding
7.7
Food
6.7
Reviews
1 / 20
8.0
ExcellentAsha,Sep 2026
LGA - IAH
Related info for your journey
Find useful and relevant information for your journey from Panama City to Louisville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Louisville?
Book flights to Louisville if you plan to visit one of these locationsShepherdsville
Elizabethtown
Jeffersonville
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Complete your trip
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Other flights to Louisville
Explore flights to Louisville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 30, 2026.
Panama City and Louisville flights
Browse other Panama City and Louisville flight options. Last updated on October 30, 2026.
Other flights from Panama City
Browse through other flights departing from Panama City. Flights are based on user searches made on Cheapflights and were last updated on October 30, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from Panama City to Louisville
Discover the top airline that operate flights from Panama City to Louisville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 30, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$380 | Average$730 | FlexibilityNo cancel fee | On-time69% |