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$319+ Cheap flights from Panama City (PTY) to Louisville (SDF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/24. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — SDF
Jul 10 — Jul 171
Fri 7/10
Fri 7/17
1 adult, Economy
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Cheap flight deals from Panama City to Louisville

Cheapest flights from Panama City to Louisville
Explore the most affordable flight options available from Panama City to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 10, 2026.

This United Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/243:30 pm
PTY
-
SDF
1 stop19h 24m
United Airlines
Fri 7/316:15 am
SDF
-
PTY
1 stop13h 22m
United Airlines
Deal found 6/9$656
This United Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/134:41 pm
PTY
-
SDF
2 stops24h 08m
United Airlines
Tue 11/177:05 am
SDF
-
PTY
1 stop7h 40m
United Airlines
Deal found 6/7$667
This United Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/610:00 am
PTY
-
SDF
1 stop9h 01m
United Airlines
Fri 7/1711:44 am
SDF
-
PTY
1 stop17h 20m
United Airlines
Deal found 6/7$714
This American Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/61:14 pm
PTY
-
SDF
2 stops21h 33m
American Airlines
Fri 7/178:19 pm
SDF
-
PTY
2 stops16h 55m
American Airlines
Deal found 6/7$752
This United Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/153:30 pm
PTY
-
SDF
2 stops16h 56m
United Airlines
Tue 6/237:47 pm
SDF
-
PTY
2 stops19h 27m
United Airlines
Deal found 6/8$839
This American Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/151:15 pm
PTY
-
SDF
2 stops20h 20m
American Airlines
Tue 6/237:18 pm
SDF
-
PTY
2 stops17h 55m
American Airlines
Deal found 6/7$854

Find flight deals from Panama City to Louisville

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Louisville (SDF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 10, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$656
(United Airlines)

One-way from

$319
(Kiwi.com)

Popular in

January

Cheapest in

November

Average price

$1,010
Provider with most accurate pricing for Panama City Tocumen Intl-Louisville Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Panama City Tocumen Intl-Louisville Intl flights.
Search Deals
From Panama City Tocumen Intl to Louisville Intl
Search Deals
One-way flight from Panama City Tocumen Intl to Louisville Intl
Search Deals
Highest demand for flights based on searches. 11% potential increase in price ($94 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($30 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in June 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 10, 2026.
Use the filters below to find and compare flights from Panama City to Louisville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Fri 7/24

9:45 am-8:25 pm

1 stop9h 40m

Louisville Intl

Fri 7/31

7:55 pm-4:12 pm

2 stops21h 17m

$656

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Fri 11/13

4:41 pm-1:00 pm

2 stops20h 19m

Louisville Intl

Tue 11/17

7:05 am-2:45 pm

1 stop7h 40m

$667
Quickest round-trip

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Mon 7/6

10:00 am-8:01 pm

1 stop9h 01m

Louisville Intl

Fri 7/17

11:44 am-4:04 am

1 stop17h 20m

$714
Cheapest one-way

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Fri 7/24

4:25 am-7:58 pm

2 stops14h 33m

$336

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Wed 8/12

2:20 pm-12:24 am

1 stop9h 04m

$360

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Wed 8/12

3:30 pm-4:38 pm

2 stops24h 08m

$360
Quickest one-way

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Fri 7/24

2:24 pm-12:26 am

1 stop9h 02m

$362

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Fri 7/24

9:45 am-8:25 pm

1 stop9h 40m

$362

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Wed 6/24

10:00 am-9:22 am

2 stops22h 22m

$415

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Tue 6/30

9:45 am-9:26 am

2 stops22h 41m

$415

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/9

Showing 1-10 of 12 resultsSorted by cheapest first
1
2
  • Most accurate provider: When it comes to deals on Panama City-Louisville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City-Louisville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City-Louisville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Panama City-Louisville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City-Louisville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Panama City to Louisville

Have a flexible travel schedule? Discover the best time to fly to Louisville from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Louisville

What is the cheapest month to book a flight from Panama City to Louisville?

Currently, November is the cheapest month in which you can book a flight from Panama City to Louisville (average of $451). Flying from Panama City to Louisville in January is currently the most expensive (average of $1,014). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Panama City to Louisville?

Reviews of airlines servicing Louisville

Get insights into the airlines that provide service to Louisville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Louisville. Reviews last updated June 10, 2026.
Peruse reviews from past customers who have flown with United Airlines from Panama City to Louisville to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,804 reviews

Boarding

7.7

Overall

7.4

Entertainment

7.1

Comfort

7.3

Food

6.6

Crew

8.1

Reviews

1 / 20
4.0
Okay

Dynasty,May 2026

LAX - EWR

The food wasn’t nice - Hosts were not that kind.
United Airlines
7.4
Good
9,804 reviews
United Airlines
7.4
Good
9,804 reviews

Boarding

7.7

Overall

7.4

Entertainment

7.1

Comfort

7.3

Food

6.6

Crew

8.1

Reviews

1 / 20
4.0
Okay

Dynasty,May 2026

LAX - EWR

The food wasn’t nice - Hosts were not that kind.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Louisville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Panama City to Louisville?

    For as low as $656, United Airlines can have you in Louisville from Panama City in 9h 40m. There are 2048 mi between Panama City and Louisville.

  • What is the cheapest airline to fly from Panama City to Louisville round-trip?

    Flying on United Airlines is currently your cheapest option to Louisville, with prices starting at $451. You may be able to fly from Panama City to Louisville for 34% less than the average price by searching for this airline.

  • Can I find deals for flights from Panama City to Louisville that include hotel bookings?

    Yes. In addition to deals on Panama City to Louisville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Louisville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Louisville.

  • Can I find deals for business class flights from Panama City to Louisville?

    Yes. Cheapflights offers flight deals from Panama City to Louisville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Louisville?

    Currently, November is the cheapest month in which you can book a flight from Panama City to Louisville (average of $451). Flying from Panama City to Louisville in January is currently the most expensive (average of $1,014). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Louisville?

Book flights to Louisville if you plan to visit one of these locations
Corydon
Shepherdsville
Elizabethtown
Jeffersonville
Bardstown

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Panama City to Louisville

See prices for flight routes from nearby airports that may be better suited for you.
Panama City to Cincinnati flights
Panama City to Nashville flights

Top airline flying from Panama City to Louisville

Discover the top airline that operate flights from Panama City to Louisville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 10, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$451Average$730FlexibilityNo cancel feeOn-time69%

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