$301+ Cheap flights from Louisville (SDF) to Panama City (PTY)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/4. Fares are subject to change and may not be available on all flights or dates of travel.
SDF — PTY
Dec 2 — Dec 91
Round-trip
1 adult, Economy
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Find cheap flights from Louisville to Panama City with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Louisville to Panama City
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Cheapest flights from Louisville to Panama CityExplore the most affordable flight options available from Louisville to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 2, 2026.
Explore the most affordable flight options available from Louisville to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 2, 2026.
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/316:50 am -
1 stop10h 22m
Wed 3/38:55 am -
1 stop13h 00m
Deal found 10/30![United Airlines logo]()
$667
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/317:00 am -
2 stops12h 38m
Tue 3/28:55 am -
2 stops15h 04m
Deal found 10/30![United Airlines logo]()
$672
This Delta deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/296:55 pm -
1 stop26h 50m
Tue 3/23:20 pm -
1 stop7h 15m
Deal found 10/30![Delta logo]()
$675
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/312:20 pm -
1 stop7h 25m
Sat 2/273:20 pm -
1 stop7h 15m
Deal found 10/29![Delta logo]()
$701
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/296:50 am -
1 stop12h 48m
Wed 3/310:00 am -
1 stop13h 30m
Deal found 10/29![United Airlines logo]()
$709
This Delta deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3012:14 pm -
1 stop9h 31m
Sat 2/271:40 pm -
1 stop20h 14m
Deal found 10/30![Delta logo]()
$710
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/296:50 am -
1 stop12h 48m
Tue 3/28:55 am -
2 stops15h 04m
Deal found 10/29![United Airlines logo]()
$714
This Delta deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/296:55 pm -
1 stop26h 50m
Wed 3/33:20 pm -
1 stop7h 15m
Deal found 10/30![Delta logo]()
$717
This Delta deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/296:55 pm -
1 stop26h 50m
Sat 2/273:20 pm -
1 stop18h 34m
Deal found 10/30![Delta logo]()
$718
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/141:59 pm -
2 stops24h 46m
Mon 12/218:55 am -
1 stop13h 03m
Deal found 10/30![United Airlines logo]()
$732
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/296:50 am -
1 stop12h 48m
Fri 2/268:55 am -
1 stop13h 00m
Deal found 10/29![United Airlines logo]()
$743
This Delta deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3012:14 pm -
1 stop9h 31m
Mon 3/13:20 pm -
1 stop8h 42m
Deal found 10/30![Delta logo]()
$746
Best flights from Louisville to Panama CityDiscover carefully curated flight deals from Louisville to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 2, 2026.
Discover carefully curated flight deals from Louisville to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 2, 2026.
This American Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/266:00 am -
1 stop9h 24m
Wed 3/32:25 pm -
1 stop9h 32m
Deal found 10/31![American Airlines logo]()
$667
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/37:00 am -
1 stop6h 55m
Wed 3/103:25 pm -
1 stop8h 37m
Deal found 10/28![Delta logo]()
$667
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/37:17 am -
2 stops12h 45m
Wed 3/109:30 am -
1 stop10h 31m
Deal found 10/28![United Airlines logo]()
$672
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/16:00 am -
1 stop14h 02m
Sun 3/711:55 pm -
1 stop13h 07m
Deal found 11/2![United Airlines logo]()
$701
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/16:50 am -
1 stop10h 22m
Mon 3/18:55 am -
1 stop13h 00m
Deal found 10/29![United Airlines logo]()
$701
Last-minute flights from Louisville to Panama CityDiscover last-minute flight deals from Louisville to Panama City. Data last updated November 2, 2026 and is based on user searches.
Discover last-minute flight deals from Louisville to Panama City. Data last updated November 2, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/89:10 am -
1 stop29h 35m
Wed 11/1810:00 am -
1 stop10h 34m
Deal found 11/2![United Airlines logo]()
$770
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/911:16 am -
1 stop8h 46m
Thu 11/1910:00 am -
1 stop10h 34m
Deal found 10/30![United Airlines logo]()
$757
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/105:43 pm -
2 stops20h 30m
Fri 11/203:34 pm -
2 stops17h 54m
Deal found 11/1![American Airlines logo]()
$762
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1011:17 am -
1 stop8h 45m
Thu 11/1910:00 am -
1 stop10h 34m
Deal found 10/30![United Airlines logo]()
$787
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/106:00 am -
1 stop14h 02m
Fri 11/2010:00 am -
1 stop10h 34m
Deal found 10/30![United Airlines logo]()
$791
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/237:00 am -
1 stop7h 45m
Mon 11/304:41 pm -
1 stop20h 57m
Deal found 10/29![United Airlines logo]()
$800
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/307:00 am -
1 stop12h 38m
Sun 12/610:00 am -
1 stop13h 59m
Deal found 10/29![United Airlines logo]()
$821
One-way flights from Louisville to Panama CitySearch for one-way flight options from Louisville to Panama City. Find affordable one-way fares based on user searches. Data last updated November 2, 2026.
Search for one-way flight options from Louisville to Panama City. Find affordable one-way fares based on user searches. Data last updated November 2, 2026.
This Delta deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/410:26 am -
1 stop11h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/30![Delta logo]()
$301
This Delta deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/34:38 pm -
1 stop29h 13m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/30![Delta logo]()
$315
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/36:00 pm -
2 stops26h 02m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/30![United Airlines logo]()
$323
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/87:00 am -
2 stops12h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/30![United Airlines logo]()
$335
This United Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/146:15 am -
1 stop13h 47m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/1![United Airlines logo]()
$343
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/118:41 pm -
3 stops44h 36m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/1![Multiple Airlines logo]()
$393
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/157:05 am -
1 stop7h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/30![United Airlines logo]()
$409
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/109:09 pm -
3 stops23h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/1![Multiple Airlines logo]()
$434
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/411:39 am -
3 stops56h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/30![Multiple Airlines logo]()
$438
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/88:41 pm -
3 stops33h 19m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/30![Multiple Airlines logo]()
$454
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/79:09 pm -
3 stops23h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/30![Multiple Airlines logo]()
$456
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/1411:03 am -
2 stops26h 23m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/1![American Airlines logo]()
$458
Find flight deals from Louisville to Panama City
Discover tips and strategies to find the most affordable flight options for your journey from Louisville (SDF) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 2, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $667 (United Airlines) |
One-way from | $301 (United Airlines) |
Popular in | October |
Cheapest in | December |
Average price | $694 |
Cheapflights Fare Finder
Customize your flight search to find flights from Louisville to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 2, 2026.
Use the filters below to find and compare flights from Louisville to Panama City that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
LouisvillePanama City
SDF Louisville Intl - PTY Panama City Tocumen Intl
SDFPTY
Louisville Intl
Tue 1/12
7:00 am-8:02 pm
2 stops13h 02m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$301
LouisvillePanama City
SDF Louisville Intl - PTY Panama City Tocumen Intl
SDFPTY
Louisville Intl
Mon 1/4
8:45 am-5:10 am
2 stops20h 25m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$301
LouisvillePanama City
SDF Louisville Intl - PTY Panama City Tocumen Intl
SDFPTY
Louisville Intl
Tue 1/5
8:45 am-8:02 pm
1 stop11h 17m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$301
Quickest round-trip
LouisvillePanama City
SDF Louisville Intl - PTY Panama City Tocumen Intl
SDFPTY
Louisville Intl
Wed 1/13
8:50 am-8:02 pm
2 stops11h 12m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$301
LouisvillePanama City
SDF Louisville Intl - PTY Panama City Tocumen Intl
SDFPTY
Louisville Intl
Sat 1/9
7:00 am-8:02 pm
2 stops13h 02m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$335
LouisvillePanama City
SDF Louisville Intl - PTY Panama City Tocumen Intl
SDFPTY
Louisville Intl
Fri 1/8
7:00 am-7:38 pm
2 stops12h 38m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$335
LouisvillePanama City
SDF Louisville Intl - PTY Panama City Tocumen Intl
SDFPTY
Louisville Intl
Mon 12/21
8:07 pm-1:41 pm
2 stops17h 34m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$536
LouisvillePanama City
SDF Louisville Intl - PTY Panama City Tocumen Intl
SDFPTY
Louisville Intl
Fri 2/26
6:00 am-3:24 pm
1 stop9h 24m
Panama City Tocumen Intl
Wed 3/3
2:25 pm-11:57 pm
1 stop9h 32m
$667
LouisvillePanama City
SDF Louisville Intl - PTY Panama City Tocumen Intl
SDFPTY
Louisville Intl
Wed 3/3
7:00 am-1:55 pm
1 stop6h 55m
Panama City Tocumen Intl
Wed 3/10
3:25 pm-12:02 am
1 stop8h 37m
$667
LouisvillePanama City
SDF Louisville Intl - PTY Panama City Tocumen Intl
SDFPTY
Louisville Intl
Wed 3/3
7:17 am-8:02 pm
2 stops12h 45m
Panama City Tocumen Intl
Wed 3/10
9:30 am-8:01 pm
1 stop10h 31m
$672
Showing 1-10 of 12 resultsSorted by cheapest first
Compare providers for flights from Louisville to Panama City
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Louisville to Panama City in November.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Louisville-Panama City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Louisville-Panama City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Louisville-Panama City flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Louisville-Panama City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Louisville-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Louisville to Panama City
Have a flexible travel schedule? Discover the best time to fly to Panama City from Louisville with our price prediction graph.
SDF-PTY
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Louisville to Panama City
What is the cheapest month to book a flight from Louisville to Panama City?
Currently, December is the cheapest month in which you can book a flight from Louisville to Panama City (average of $473). Flying from Louisville to Panama City in October is currently the most expensive (average of $801). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Louisville to Panama City?
Airfare is typical for this route at the moment.
Louisville to Panama City flights typically cost between $648 and $758 in December.The cheapest round-trip price found within the last 5 days was $667 on United Airlines (Dec 31-Mar 3).
Reviews of airlines servicing Panama City
Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated November 2, 2026.
Read through reviews of airlines operating flights from Louisville to Panama City, such as Delta,United Airlines, andAmerican Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.8
Comfort
7.8
Overall
7.8
Crew
8.5
Boarding
8.1
Food
7.2
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Entertainment
7.8
Comfort
7.8
Overall
7.8
Crew
8.5
Boarding
8.1
Food
7.2
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Entertainment
7.8
Comfort
7.8
Overall
7.8
Crew
8.5
Boarding
8.1
Food
7.2
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Entertainment
7.8
Comfort
7.8
Overall
7.8
Crew
8.5
Boarding
8.1
Food
7.2
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Related info for your journey
Find useful and relevant information for your journey from Louisville to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Complete your trip
Complete your trip to Panama City by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Louisville to Panama City by cabin class
Find flights from Louisville to Panama City, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Louisville and Panama City flights
Browse other Louisville and Panama City flight options. Last updated on November 2, 2026.
Other flights from Louisville
Browse through other flights departing from Louisville. Flights are based on user searches made on Cheapflights and were last updated on November 2, 2026.
Other flights to Panama City
Explore flights to Panama City departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on November 2, 2026.
Popular flight searches
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Top 3 airlines flying from Louisville to Panama City
Discover the top 3 airlines that operate flights from Louisville to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 2, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$430 | Average$591 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$514 | Average$769 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$558 | Average$680 | FlexibilityNo cancel fee | On-timeN/A |