$266+ Cheap flights from Louisville (SDF) to Panama City (PTY)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/17. Fares are subject to change and may not be available on all flights or dates of travel.
SDF — PTY
Oct 2 — Oct 91
Round-trip
1 adult, Economy
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Find cheap flights from Louisville to Panama City with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Louisville to Panama City
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Best
Last-minute
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Cheapest flights from Louisville to Panama CityExplore the most affordable flight options available from Louisville to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 2, 2026.
Explore the most affordable flight options available from Louisville to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 2, 2026.
This United Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2811:15 am -
1 stop8h 47m
Wed 11/410:00 am -
1 stop13h 30m
Deal found 9/1![United Airlines logo]()
$597
This United Airlines deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/106:18 pm -
1 stop25h 44m
Thu 11/198:55 am -
1 stop11h 38m
Deal found 8/30![United Airlines logo]()
$606
This United Airlines deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/196:15 am -
1 stop14h 16m
Fri 10/239:45 am -
1 stop9h 28m
Deal found 8/30![United Airlines logo]()
$631
This American Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/198:18 pm -
2 stops17h 44m
Sun 10/252:02 pm -
2 stops21h 06m
Deal found 8/28![American Airlines logo]()
$640
This United Airlines deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/167:25 am -
1 stop12h 12m
Mon 3/810:00 am -
1 stop13h 15m
Deal found 8/30![United Airlines logo]()
$642
This United Airlines deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/106:18 pm -
1 stop25h 44m
Fri 11/204:41 pm -
2 stops20h 56m
Deal found 8/30![United Airlines logo]()
$644
This Delta deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/26:00 am -
1 stop7h 59m
Mon 11/93:29 pm -
1 stop17h 37m
Deal found 8/30![Delta logo]()
$645
Best flights from Louisville to Panama CityDiscover carefully curated flight deals from Louisville to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 2, 2026.
Discover carefully curated flight deals from Louisville to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 2, 2026.
This United Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2811:15 am -
1 stop8h 47m
Wed 11/410:00 am -
1 stop13h 30m
Deal found 9/1![United Airlines logo]()
$597
This American Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/198:18 pm -
2 stops17h 44m
Sun 10/252:02 pm -
2 stops21h 06m
Deal found 8/28![American Airlines logo]()
$640
This United Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/17:05 am -
1 stop12h 33m
Sun 3/711:55 pm -
1 stop17h 35m
Deal found 9/1![United Airlines logo]()
$631
This United Airlines deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/17:00 am -
1 stop12h 38m
Mon 11/98:55 am -
1 stop11h 38m
Deal found 8/30![United Airlines logo]()
$631
This United Airlines deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/167:25 am -
1 stop12h 12m
Mon 3/810:00 am -
1 stop13h 15m
Deal found 8/30![United Airlines logo]()
$642
Last-minute flights from Louisville to Panama CityDiscover last-minute flight deals from Louisville to Panama City. Data last updated September 2, 2026 and is based on user searches.
Discover last-minute flight deals from Louisville to Panama City. Data last updated September 2, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/167:25 am -
1 stop12h 12m
Mon 3/810:00 am -
1 stop13h 15m
Deal found 8/30![United Airlines logo]()
$642
This United Airlines deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1411:15 am -
1 stop9h 16m
Tue 10/209:45 am -
1 stop9h 28m
Deal found 8/30![United Airlines logo]()
$657
This United Airlines deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/196:15 am -
1 stop14h 16m
Fri 10/239:45 am -
1 stop9h 28m
Deal found 8/30![United Airlines logo]()
$631
This American Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/198:18 pm -
2 stops17h 44m
Sun 10/252:02 pm -
2 stops21h 06m
Deal found 8/28![American Airlines logo]()
$640
This United Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/196:15 am -
1 stop14h 16m
Thu 10/229:45 am -
1 stop9h 28m
Deal found 9/1![United Airlines logo]()
$659
This United Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2811:15 am -
1 stop8h 47m
Wed 11/410:00 am -
1 stop13h 30m
Deal found 9/1![United Airlines logo]()
$597
One-way flights from Louisville to Panama CitySearch for one-way flight options from Louisville to Panama City. Find affordable one-way fares based on user searches. Data last updated September 2, 2026.
Search for one-way flight options from Louisville to Panama City. Find affordable one-way fares based on user searches. Data last updated September 2, 2026.
This United Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/175:57 pm -
2 stops23h 15m
Deal found 8/28![United Airlines logo]()
$266
This United Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/111:45 pm -
1 stop30h 17m
Deal found 8/28![United Airlines logo]()
$280
This Delta deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/176:00 am -
1 stop7h 55m
Deal found 8/28![Delta logo]()
$300
This United Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/56:15 am -
1 stop14h 16m
Deal found 8/31![United Airlines logo]()
$328
This United Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/107:10 am -
2 stops12h 27m
Deal found 9/1![United Airlines logo]()
$360
This Kiwi.com deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/57:59 pm -
3 stops41h 29m
Deal found 8/31![Multiple Airlines logo]()
$369
This Delta deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/137:00 am -
1 stop7h 03m
Deal found 8/31![Delta logo]()
$378
This Kiwi.com deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/114:06 pm -
3 stops39h 43m
Deal found 8/28![Multiple Airlines logo]()
$384
This Kiwi.com deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/139:09 pm -
2 stops23h 22m
Deal found 8/31![Multiple Airlines logo]()
$449
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/154:10 pm -
2 stops22h 03m
Deal found 9/2![American Airlines logo]()
$558
Find flight deals from Louisville to Panama City
Discover tips and strategies to find the most affordable flight options for your journey from Louisville (SDF) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 2, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $597 (United Airlines) |
One-way from | $266 (United Airlines) |
Popular in | July |
Cheapest in | February |
Average price | $688 |
Cheapflights Fare Finder
Customize your flight search to find flights from Louisville to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 2, 2026.
Use the filters below to find and compare flights from Louisville to Panama City that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
LouisvillePanama City
SDF Louisville Intl - PTY Panama City Tocumen Intl
SDFPTY
Louisville Intl
Wed 10/28
11:15 am-7:02 pm
1 stop8h 47m
Panama City Tocumen Intl
Wed 11/4
10:00 am-11:30 pm
1 stop13h 30m
$597
LouisvillePanama City
SDF Louisville Intl - PTY Panama City Tocumen Intl
SDFPTY
Louisville Intl
Mon 3/1
7:05 am-7:38 pm
1 stop12h 33m
Panama City Tocumen Intl
Sun 3/7
11:55 pm-5:30 pm
1 stop17h 35m
$631
LouisvillePanama City
SDF Louisville Intl - PTY Panama City Tocumen Intl
SDFPTY
Louisville Intl
Sun 11/1
7:00 am-7:38 pm
1 stop12h 38m
Panama City Tocumen Intl
Mon 11/9
8:55 am-8:33 pm
1 stop11h 38m
$631
LouisvillePanama City
SDF Louisville Intl - PTY Panama City Tocumen Intl
SDFPTY
Louisville Intl
Mon 10/19
8:18 pm-1:02 pm
2 stops17h 44m
Panama City Tocumen Intl
Sun 10/25
2:02 pm-12:08 pm
2 stops21h 06m
$640
LouisvillePanama City
SDF Louisville Intl - PTY Panama City Tocumen Intl
SDFPTY
Louisville Intl
Wed 9/16
7:25 am-6:37 pm
1 stop12h 12m
Panama City Tocumen Intl
Mon 3/8
10:00 am-11:15 pm
1 stop13h 15m
$642
Cheapest one-way
LouisvillePanama City
SDF Louisville Intl - PTY Panama City Tocumen Intl
SDFPTY
Louisville Intl
Sun 1/17
5:57 pm-5:12 pm
2 stops23h 15m
$266
LouisvillePanama City
SDF Louisville Intl - PTY Panama City Tocumen Intl
SDFPTY
Louisville Intl
Wed 11/11
1:45 pm-8:02 pm
1 stop30h 17m
$280
LouisvillePanama City
SDF Louisville Intl - PTY Panama City Tocumen Intl
SDFPTY
Louisville Intl
Sun 1/17
6:00 am-1:55 pm
1 stop7h 55m
$300
LouisvillePanama City
SDF Louisville Intl - PTY Panama City Tocumen Intl
SDFPTY
Louisville Intl
Mon 10/5
9:04 am-7:31 pm
2 stops11h 27m
$328
LouisvillePanama City
SDF Louisville Intl - PTY Panama City Tocumen Intl
SDFPTY
Louisville Intl
Thu 9/10
7:25 am-2:14 pm
1 stop7h 49m
$360
Showing 1-10 of 13 resultsSorted by cheapest first
Compare providers for flights from Louisville to Panama City
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Louisville to Panama City in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Louisville-Panama City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Louisville-Panama City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Louisville-Panama City flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Louisville-Panama City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Louisville-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Louisville to Panama City
Have a flexible travel schedule? Discover the best time to fly to Panama City from Louisville with our price prediction graph.
SDF-PTY
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Louisville to Panama City
Reviews of airlines servicing Panama City
Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated September 2, 2026.
Read through reviews of airlines operating flights from Louisville to Panama City, such as Delta,United Airlines, andAmerican Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Comfort
7.8
Entertainment
7.8
Crew
8.5
Food
7.2
Overall
7.8
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Boarding
8.1
Comfort
7.8
Entertainment
7.8
Crew
8.5
Food
7.2
Overall
7.8
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Boarding
8.1
Comfort
7.8
Entertainment
7.8
Crew
8.5
Food
7.2
Overall
7.8
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Boarding
8.1
Comfort
7.8
Entertainment
7.8
Crew
8.5
Food
7.2
Overall
7.8
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Related info for your journey
Find useful and relevant information for your journey from Louisville to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Complete your trip
Complete your trip to Panama City by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Louisville to Panama City by cabin class
Find flights from Louisville to Panama City, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Louisville and Panama City flights
Browse other Louisville and Panama City flight options. Last updated on September 2, 2026.
Other flights from Louisville
Browse through other flights departing from Louisville. Flights are based on user searches made on Cheapflights and were last updated on September 2, 2026.
Other flights to Panama City
Explore flights to Panama City departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 2, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from Louisville to Panama City
Discover the top 3 airlines that operate flights from Louisville to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 2, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$430 | Average$558 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$436 | Average$720 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$558 | Average$663 | FlexibilityNo cancel fee | On-timeN/A |