What are the cheapest airlines flying from Knoxville to Panama City round-trip?

Flying on American Airlines is currently your cheapest option to Panama City, with prices starting at $372. Additional round-trip tickets that might be worth considering are offered by Delta and Undisclosed Carrier, with the lowest prices starting at $398 and $680, respectively. American Airlines is currently priced 44% below the average price you’ll pay for this route.

What are the most popular airlines that fly from Knoxville to Panama City?

American Airlines, Delta and United Airlines are the most popular airlines when flying from Knoxville to Panama City.

Can I find flights from Knoxville to Panama City for under $400 on Cheapflights?

Yes, there are multiple flights from Knoxville to Panama City for under $400. The cheapest flight booked recently is on American Airlines for just $372, but on average you can expect to pay $644.

Are there nonstop flights from Knoxville to Panama City for under $700 on Cheapflights?

Cheapflights has at least 2 direct flights from Knoxville to Panama City under $700. A good price for a nonstop flight from Knoxville to Panama City is less than $780.

Are there last-minute flights available from Knoxville to Panama City for under $600?

There are currently 5+ open flights from Knoxville to Panama City within the next 7 days for less than $600.

Which airlines flying from Knoxville McGhee Tyson to Panama City Tocumen Intl have flexible cancellations due to COVID-19?

Due to the rapidly changing circumstances due to COVID-19, airlines like American Airlines, Delta, and United Airlines flying from Knoxville McGhee Tyson to Panama City Tocumen Intl have implemented new flexible cancellation policies.

What is the cheapest day to fly round-trip from Knoxville to Panama City?

Monday is generally a great day to depart. Flying on this day could help you save up to 78%.

What is the cheapest month to fly from Knoxville to Panama City?

Our data shows that August tends to be the cheapest month to fly to Panama City from Knoxville. Users have commonly found prices around $671 for the month, but tickets can be as low as $434. Due to multiple factors, prepare for potentially higher prices in December.

When is the cheapest time to fly from Knoxville to Panama City (TYS - PTY)?

A simple way to save on the total cost of your ticket is to fly from Knoxville to Panama City in the morning. If you’re flexible enough to do this you can expect to save up to 35% on your trip compared to booking a flight at noon.

What does TYS to PTY mean?

This is defined as Knoxville McGhee Tyson Airport (TYS) and Panama City Tocumen Intl Airport (PTY). Codes like Panama City Tocumen Intl Airport are often used to just call airports uniquely.

Flights from Knoxville, TN to Panama City, Panama from $372

How to find the cheapest flight from Knoxville (TYS) to Panama City (PTY)

Popular in	December
Cheapest in	August
Average price	$561
Round-trip from	$462

High demand for flights, 49% potential price rise

Search Deals

Best time to find cheap flights, 31% potential price drop

Search Deals

Average for round-trip flights in May 2023

Search Deals

From Knoxville McGhee Tyson to Panama City Tocumen Intl

Search Deals

TYS - PTY Price	$462 - $1,319
PTY Temperature	78.8 - 80.6 °F
PTY Rainfall	0.4 - 13.4 inches

TYS - PTY

Price

$462 - $1,319

PTY

Temperature

78.8 - 80.6 °F

PTY

Rainfall

0.4 - 13.4 inches

Cheap flights from Knoxville to Panama City in May, June 2023

Check out some of the best flight deals from Knoxville to Panama City in 2023. Check back in a little while for more flight options.

Jun 21 - Jun 28

TYS

Knoxville McGhee Tyson

PTY

Panama City Tocumen Intl

1 stop

7h 09m

PTY

Panama City Tocumen Intl

TYS

Knoxville McGhee Tyson

1 stop

8h 38m

$484

Delta

Deal found 5/24

Jun 20 - Jun 27

TYS

Knoxville McGhee Tyson

PTY

Panama City Tocumen Intl

2 stops

18h 28m

PTY

Panama City Tocumen Intl

TYS

Knoxville McGhee Tyson

2 stops

21h 02m

$502

American Airlines

Deal found 5/23

Jun 20 - Jun 27

TYS

Knoxville McGhee Tyson

PTY

Panama City Tocumen Intl

1 stop

7h 41m

PTY

Panama City Tocumen Intl

TYS

Knoxville McGhee Tyson

2 stops

21h 02m

$574

American Airlines

Deal found 5/23

Jun 3 - Jun 10

TYS

Knoxville McGhee Tyson

PTY

Panama City Tocumen Intl

1 stop

7h 22m

PTY

Panama City Tocumen Intl

TYS

Knoxville McGhee Tyson

1 stop

20h 57m

$589

United Airlines

Deal found 5/24

Jun 20 - Jun 27

TYS

Knoxville McGhee Tyson

PTY

Panama City Tocumen Intl

1 stop

7h 17m

PTY

Panama City Tocumen Intl

TYS

Knoxville McGhee Tyson

1 stop

25h 10m

$612

Multiple Airlines

Deal found 5/23

Jun 21 - Jun 28

TYS

Knoxville McGhee Tyson

PTY

Panama City Tocumen Intl

1 stop

5h 58m

PTY

Panama City Tocumen Intl

TYS

Knoxville McGhee Tyson

2 stops

32h 14m

$626

American Airlines

Deal found 5/24

Jun 3 - Jun 10

TYS

Knoxville McGhee Tyson

PTY

Panama City Tocumen Intl

2 stops

16h 28m

PTY

Panama City Tocumen Intl

TYS

Knoxville McGhee Tyson

2 stops

21h 02m

$732

American Airlines

Deal found 5/24

Jun 24 - Jul 1

TYS

Knoxville McGhee Tyson

PTY

Panama City Tocumen Intl

2 stops

28h 17m

PTY

Panama City Tocumen Intl

TYS

Knoxville McGhee Tyson

1 stop

8h 05m

$754

Multiple Airlines

Deal found 5/24

Jun 21 - Jun 28

TYS

Knoxville McGhee Tyson

PTY

Panama City Tocumen Intl

1 stop

11h 39m

PTY

Panama City Tocumen Intl

TYS

Knoxville McGhee Tyson

3 stops

32h 02m

$795

Multiple Airlines

Deal found 5/24

Knoxville to Panama City 2023 flight deals

Check out some of the best flight deals from Knoxville to Panama City in 2023. Check back in a little while for more flight options.

Oct 7 - Oct 14

TYS

Knoxville McGhee Tyson

PTY

Panama City Tocumen Intl

2 stops

19h 22m

PTY

Panama City Tocumen Intl

TYS

Knoxville McGhee Tyson

2 stops

19h 37m

$372

American Airlines

Deal found 5/24

Oct 7 - Oct 14

TYS

Knoxville McGhee Tyson

PTY

Panama City Tocumen Intl

1 stop

5h 55m

PTY

Panama City Tocumen Intl

TYS

Knoxville McGhee Tyson

1 stop

14h 44m

$398

Delta

Deal found 5/24

Jul 21 - Jul 27

TYS

Knoxville McGhee Tyson

PTY

Panama City Tocumen Intl

1 stop

6h 07m

PTY

Panama City Tocumen Intl

TYS

Knoxville McGhee Tyson

1 stop

8h 14m

$469

Delta

Deal found 5/24

Jun 21 - Jun 28

TYS

Knoxville McGhee Tyson

PTY

Panama City Tocumen Intl

1 stop

7h 09m

PTY

Panama City Tocumen Intl

TYS

Knoxville McGhee Tyson

1 stop

8h 38m

$484

Delta

Deal found 5/24

Jun 20 - Jun 27

TYS

Knoxville McGhee Tyson

PTY

Panama City Tocumen Intl

2 stops

18h 28m

PTY

Panama City Tocumen Intl

TYS

Knoxville McGhee Tyson

2 stops

21h 02m

$502

American Airlines

Deal found 5/23

Jul 10 - Jul 19

TYS

Knoxville McGhee Tyson

PTY

Panama City Tocumen Intl

2 stops

19h 14m

PTY

Panama City Tocumen Intl

TYS

Knoxville McGhee Tyson

2 stops

20h 24m

$561

American Airlines

Deal found 5/25

Jun 20 - Jun 27

TYS

Knoxville McGhee Tyson

PTY

Panama City Tocumen Intl

1 stop

7h 41m

PTY

Panama City Tocumen Intl

TYS

Knoxville McGhee Tyson

2 stops

21h 02m

$574

American Airlines

Deal found 5/23

Jun 3 - Jun 10

TYS

Knoxville McGhee Tyson

PTY

Panama City Tocumen Intl

1 stop

7h 22m

PTY

Panama City Tocumen Intl

TYS

Knoxville McGhee Tyson

1 stop

20h 57m

$589

United Airlines

Deal found 5/24

Jul 21 - Jul 27

TYS

Knoxville McGhee Tyson

PTY

Panama City Tocumen Intl

2 stops

20h 59m

PTY

Panama City Tocumen Intl

TYS

Knoxville McGhee Tyson

2 stops

18h 46m

$606

American Airlines

Deal found 5/24

Cheap Delta flights from Knoxville to Panama City

Take a peek at the cheapest Delta flights we've detected traveling from Knoxville to Panama City. Come back soon if you're not finding the exact deal you're looking for.

Oct 7 - Oct 14

TYS

Knoxville McGhee Tyson

PTY

Panama City Tocumen Intl

1 stop

5h 55m

PTY

Panama City Tocumen Intl

TYS

Knoxville McGhee Tyson

1 stop

14h 44m

$398

Delta

Deal found 5/24

Jul 21 - Jul 27

TYS

Knoxville McGhee Tyson

PTY

Panama City Tocumen Intl

1 stop

6h 07m

PTY

Panama City Tocumen Intl

TYS

Knoxville McGhee Tyson

1 stop

8h 14m

$469

Delta

Deal found 5/24

Jun 21 - Jun 28

TYS

Knoxville McGhee Tyson

PTY

Panama City Tocumen Intl

1 stop

7h 09m

PTY

Panama City Tocumen Intl

TYS

Knoxville McGhee Tyson

1 stop

8h 38m

$484

Delta

Deal found 5/24

Cheap American Airlines flights from Knoxville to Panama City

Take a gander at the lowest prices we've found on American Airlines flights from Knoxville to Panama City. Make sure to examine the flight information before completing your reservation.

Oct 7 - Oct 14

TYS

Knoxville McGhee Tyson

PTY

Panama City Tocumen Intl

2 stops

19h 22m

PTY

Panama City Tocumen Intl

TYS

Knoxville McGhee Tyson

2 stops

19h 37m

$372

American Airlines

Deal found 5/24

Jun 20 - Jun 27

TYS

Knoxville McGhee Tyson

PTY

Panama City Tocumen Intl

2 stops

18h 28m

PTY

Panama City Tocumen Intl

TYS

Knoxville McGhee Tyson

2 stops

21h 02m

$502

American Airlines

Deal found 5/23

Jul 10 - Jul 19

TYS

Knoxville McGhee Tyson

PTY

Panama City Tocumen Intl

2 stops

19h 14m

PTY

Panama City Tocumen Intl

TYS

Knoxville McGhee Tyson

2 stops

20h 24m

$561

American Airlines

Deal found 5/25

Jun 20 - Jun 27

TYS

Knoxville McGhee Tyson

PTY

Panama City Tocumen Intl

1 stop

7h 41m

PTY

Panama City Tocumen Intl

TYS

Knoxville McGhee Tyson

2 stops

21h 02m

$574

American Airlines

Deal found 5/23

Jun 21 - Jun 28

TYS

Knoxville McGhee Tyson

PTY

Panama City Tocumen Intl

2 stops

16h 28m

PTY

Panama City Tocumen Intl

TYS

Knoxville McGhee Tyson

2 stops

32h 14m

$589

American Airlines

Deal found 5/24

Jul 21 - Jul 27

TYS

Knoxville McGhee Tyson

PTY

Panama City Tocumen Intl

2 stops

20h 59m

PTY

Panama City Tocumen Intl

TYS

Knoxville McGhee Tyson

2 stops

18h 46m

$606

American Airlines

Deal found 5/24

Jul 10 - Jul 19

TYS

Knoxville McGhee Tyson

PTY

Panama City Tocumen Intl

2 stops

20h 59m

PTY

Panama City Tocumen Intl

TYS

Knoxville McGhee Tyson

1 stop

9h 21m

$607

American Airlines

Deal found 5/25

Jun 21 - Jun 28

TYS

Knoxville McGhee Tyson

PTY

Panama City Tocumen Intl

1 stop

5h 58m

PTY

Panama City Tocumen Intl

TYS

Knoxville McGhee Tyson

2 stops

32h 14m

$626

American Airlines

Deal found 5/24

Jun 3 - Jun 10

TYS

Knoxville McGhee Tyson

PTY

Panama City Tocumen Intl

2 stops

16h 28m

PTY

Panama City Tocumen Intl

TYS

Knoxville McGhee Tyson

2 stops

21h 02m

$732

American Airlines

Deal found 5/24

Non-stop flights to Panama City from Knoxville

To help reduce your travel time, choose from one of these non-stop flights from Knoxville to Panama City. Users can also choose from other Knoxville to Panama City flights by using the search form above.

Jul 10 - Jul 19

TYS

Knoxville McGhee Tyson

PTY

Panama City Tocumen Intl

Nonstop

4h 44m

PTY

Panama City Tocumen Intl

TYS

Knoxville McGhee Tyson

Nonstop

2h 44m

$680

Undisclosed Carrier

Deal found 5/25

Jun 24 - Jul 1

TYS

Knoxville McGhee Tyson

PTY

Panama City Tocumen Intl

Nonstop

4h 44m

PTY

Panama City Tocumen Intl

TYS

Knoxville McGhee Tyson

Nonstop

2h 44m

$880

Undisclosed Carrier

Deal found 5/24

Last minute flights from Knoxville to Panama City

Users seeking a last-minute flight from Knoxville to Panama City should consider booking one of these fares. Tip: verify your flight details before completing your reservation.

Jun 3 - Jun 10

TYS

Knoxville McGhee Tyson

PTY

Panama City Tocumen Intl

1 stop

7h 22m

PTY

Panama City Tocumen Intl

TYS

Knoxville McGhee Tyson

1 stop

20h 57m

$589

United Airlines

Deal found 5/24

Jun 3 - Jun 10

TYS

Knoxville McGhee Tyson

PTY

Panama City Tocumen Intl

2 stops

16h 28m

PTY

Panama City Tocumen Intl

TYS

Knoxville McGhee Tyson

2 stops

21h 02m

$732

American Airlines

Deal found 5/24

Jun 3 - Jun 10

TYS

Knoxville McGhee Tyson

PTY

Panama City Tocumen Intl

2 stops

8h 56m

PTY

Panama City Tocumen Intl

TYS

Knoxville McGhee Tyson

1 stop

9h 42m

$1,024

American Airlines

Deal found 5/24

Jun 3 - Jun 10

TYS

Knoxville McGhee Tyson

PTY

Panama City Tocumen Intl

3 stops

26h 30m

PTY

Panama City Tocumen Intl

TYS

Knoxville McGhee Tyson

3 stops

22h 12m

$1,250

Multiple Airlines

Deal found 5/24

Jun 3 - Jun 10

TYS

Knoxville McGhee Tyson

PTY

Panama City Tocumen Intl

3 stops

26h 30m

PTY

Panama City Tocumen Intl

TYS

Knoxville McGhee Tyson

2 stops

46h 02m

$2,201

Multiple Airlines

Deal found 5/24

Find flights from Knoxville to Panama City within your budget

Fly from

Fly to

Budget

$372 - $1,340

Route

Depart

Return

Price

Knoxville McGhee TysonPanama City Tocumen Intl

TYS - PTY

TYSPTY

Knoxville McGhee Tyson

Sat 10/7

2 stops19h 22m

Panama City Tocumen Intl

Sat 10/14

2 stops19h 37m

$372

Pick Dates

Knoxville McGhee TysonPanama City Tocumen Intl

TYS - PTY

TYSPTY

Knoxville McGhee Tyson

Sat 10/7

1 stop5h 55m

Panama City Tocumen Intl

Sat 10/14

1 stop14h 44m

$398

Pick Dates

Knoxville McGhee TysonPanama City Tocumen Intl

TYS - PTY

TYSPTY

Knoxville McGhee Tyson

Fri 7/21

1 stop6h 07m

Panama City Tocumen Intl

Thu 7/27

1 stop8h 14m

$469

Pick Dates

Knoxville McGhee TysonPanama City Tocumen Intl

TYS - PTY

TYSPTY

Knoxville McGhee Tyson

Wed 6/21

1 stop7h 09m

Panama City Tocumen Intl

Wed 6/28

1 stop8h 38m

$484

Pick Dates

Knoxville McGhee TysonPanama City Tocumen Intl

TYS - PTY

TYSPTY

Knoxville McGhee Tyson

Tue 6/20

2 stops18h 28m

Panama City Tocumen Intl

Tue 6/27

2 stops21h 02m

$502

Pick Dates

Knoxville McGhee TysonPanama City Tocumen Intl

TYS - PTY

TYSPTY

Knoxville McGhee Tyson

Mon 7/10

2 stops19h 14m

Panama City Tocumen Intl

Wed 7/19

2 stops20h 24m

$561

Pick Dates

Knoxville McGhee TysonPanama City Tocumen Intl

TYS - PTY

TYSPTY

Knoxville McGhee Tyson

Tue 6/20

1 stop7h 17m

Panama City Tocumen Intl

Tue 6/27

1 stop25h 10m

$612

Pick Dates

Knoxville McGhee TysonPanama City Tocumen Intl

TYS - PTY

TYSPTY

Knoxville McGhee Tyson

Mon 7/10

Nonstop4h 44m

Panama City Tocumen Intl

Wed 7/19

Nonstop2h 44m

$680

Pick Dates

Knoxville McGhee TysonPanama City Tocumen Intl

TYS - PTY

TYSPTY

Knoxville McGhee Tyson

Wed 6/21

1 stop11h 31m

Panama City Tocumen Intl

Wed 6/28

1 stop11h 31m

$1,340

Pick Dates

Flights are sorted by cheapest first

Deals found on 5/24

Reviews of Airlines Servicing Panama City

To help decide which airline to fly from Knoxville to Panama City, see what other customers have to say about Delta, American Airlines and Undisclosed Carrier. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

2,341 reviews

Check prices

Reviews

1 / 10

When everything runs smoothly you barely even think about it. That’s how our flight went.

Delta

8.0

Very good

2,341 reviews

Delta

8.0

Very good

2,341 reviews

Check prices

Reviews

1 / 10

When everything runs smoothly you barely even think about it. That’s how our flight went.

American Airlines

7.4

Good

2,147 reviews

Delta

8.0

Very good

2,341 reviews

Check prices

Reviews

1 / 10

When everything runs smoothly you barely even think about it. That’s how our flight went.

Copa Airlines

7.2

Good

300 reviews

Delta

8.0

Very good

2,341 reviews

Check prices

Reviews

1 / 10

When everything runs smoothly you barely even think about it. That’s how our flight went.

Avianca

7.1

Good

713 reviews

Delta

8.0

Very good

2,341 reviews

Check prices

Reviews

1 / 10

When everything runs smoothly you barely even think about it. That’s how our flight went.

Related info for your journey

Top 3 airlines flying from Knoxville to Panama City

Airline	Cheapest	Average	Flexibility	On-time	COVID-19 safety
American Airlines	Cheapest$483	Average$666	FlexibilityNo cancel fee	On-time71%	COVID-19 safety	Search American Airlines flights
United Airlines	Cheapest$553	Average$729	FlexibilityNo cancel fee	On-time69%	COVID-19 safety	Search United Airlines flights
Delta	Cheapest$561	Average$692	FlexibilityNo cancel fee	On-timeN/A	COVID-19 safety	Search Delta flights

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Cheap flights from Knoxville (TYS) to Panama City (PTY) from $372

This is the cheapest one-way flight price, found on 5/24. Prices may vary by date and flight preferences.

How to find the cheapest flight from Knoxville (TYS) to Panama City (PTY)

All the information you need to plan the best TYS to PTY flight in 2023: compare Knoxville to Panama City flight prices with the expected peak season, weather and rainfall in Panama City.

Popular in

Cheapest in

Average price

Round-trip from

What is the cheapest day to fly round-trip from Knoxville to Panama City?

What is the cheapest month to fly from Knoxville to Panama City?

When is the cheapest time to fly from Knoxville to Panama City (TYS - PTY)?

Cheap flights from Knoxville to Panama City in May, June 2023

The best prices found for TYS to PTY flights for May, June

Check out some of the best flight deals from Knoxville to Panama City in 2023. Check back in a little while for more flight options.

Knoxville to Panama City 2023 flight deals

Cheap flights to Panama City from Knoxville found for this year

Check out some of the best flight deals from Knoxville to Panama City in 2023. Check back in a little while for more flight options.

Cheap Delta flights from Knoxville to Panama City

Take a peek at the cheapest Delta flights we've detected traveling from Knoxville to Panama City. Come back soon if you're not finding the exact deal you're looking for.

Cheap American Airlines flights from Knoxville to Panama City

Take a gander at the lowest prices we've found on American Airlines flights from Knoxville to Panama City. Make sure to examine the flight information before completing your reservation.

Non-stop flights to Panama City from Knoxville

Save time with Knoxville to Panama City direct flight deals

To help reduce your travel time, choose from one of these non-stop flights from Knoxville to Panama City. Users can also choose from other Knoxville to Panama City flights by using the search form above.

Last minute flights from Knoxville to Panama City

Late deals on return flights to Panama City from Knoxville, departing today and this week

Users seeking a last-minute flight from Knoxville to Panama City should consider booking one of these fares. Tip: verify your flight details before completing your reservation.

Find flights from Knoxville to Panama City within your budget

Use the slider to find flights from Knoxville to Panama City that fit your budget.

Reviews of Airlines Servicing Panama City

To help decide which airline to fly from Knoxville to Panama City, see what other customers have to say about Delta, American Airlines and Undisclosed Carrier. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Useful info, stats and facts about Knoxville to Panama City flights.

Which airlines flying from Knoxville McGhee Tyson to Panama City Tocumen Intl have flexible cancellations due to COVID-19?

Can I find flights from Knoxville to Panama City for under $400 on Cheapflights?

Are there nonstop flights from Knoxville to Panama City for under $700 on Cheapflights?

Are there last-minute flights available from Knoxville to Panama City for under $600?

What are the cheapest airlines flying from Knoxville to Panama City round-trip?

What are the most popular airlines that fly from Knoxville to Panama City?

What does TYS to PTY mean?

Other flights from Knoxville

Other flights to Panama City

Flights to Panama City from Knoxville

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Top 3 airlines flying from Knoxville to Panama City

The chart below displays the airlines Cheapflights users traveling from Knoxville to Panama City choose most often. Cheapest and average prices are based on aggregated data from the past 12 months.

Popular flight searches

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