Cheap flights from Knoxville (TYS) to Panama City (PTY) from $372

This is the cheapest one-way flight price, found on 5/24. Prices may vary by date and flight preferences.
TYS — PTY
May 30 — Jun 61

How to find the cheapest flight from Knoxville (TYS) to Panama City (PTY)

All the information you need to plan the best TYS to PTY flight in 2023: compare Knoxville to Panama City flight prices with the expected peak season, weather and rainfall in Panama City.

Popular in

December

Cheapest in

August

Average price

$561

Round-trip from

$462
High demand for flights, 49% potential price rise
Best time to find cheap flights, 31% potential price drop
Average for round-trip flights in May 2023
From Knoxville McGhee Tyson to Panama City Tocumen Intl

TYS - PTY

Price

$462 - $1,319

PTY

Temperature

78.8 - 80.6 °F

PTY

Rainfall

0.4 - 13.4 inches

Cheap flights from Knoxville to Panama City in May, June 2023

The best prices found for TYS to PTY flights for May, June
Check out some of the best flight deals from Knoxville to Panama City in 2023. Check back in a little while for more flight options.

Knoxville to Panama City 2023 flight deals

Cheap flights to Panama City from Knoxville found for this year
Check out some of the best flight deals from Knoxville to Panama City in 2023. Check back in a little while for more flight options.

Cheap Delta flights from Knoxville to Panama City

Take a peek at the cheapest Delta flights we've detected traveling from Knoxville to Panama City. Come back soon if you're not finding the exact deal you're looking for.

Cheap American Airlines flights from Knoxville to Panama City

Take a gander at the lowest prices we've found on American Airlines flights from Knoxville to Panama City. Make sure to examine the flight information before completing your reservation.

Non-stop flights to Panama City from Knoxville

Save time with Knoxville to Panama City direct flight deals
To help reduce your travel time, choose from one of these non-stop flights from Knoxville to Panama City. Users can also choose from other Knoxville to Panama City flights by using the search form above.

Last minute flights from Knoxville to Panama City

Late deals on return flights to Panama City from Knoxville, departing today and this week
Users seeking a last-minute flight from Knoxville to Panama City should consider booking one of these fares. Tip: verify your flight details before completing your reservation.

Find flights from Knoxville to Panama City within your budget

Use the slider to find flights from Knoxville to Panama City that fit your budget.

Fly from

Any airport

Fly to

Any airport

Budget

$372 - $1,340

Route

Depart

Return

Price

Knoxville McGhee TysonPanama City Tocumen Intl

TYS - PTY

TYSPTY

Knoxville McGhee Tyson

Sat 10/7

2 stops19h 22m

Panama City Tocumen Intl

Sat 10/14

2 stops19h 37m

Knoxville McGhee TysonPanama City Tocumen Intl

TYS - PTY

TYSPTY

Knoxville McGhee Tyson

Sat 10/7

1 stop5h 55m

Panama City Tocumen Intl

Sat 10/14

1 stop14h 44m

Knoxville McGhee TysonPanama City Tocumen Intl

TYS - PTY

TYSPTY

Knoxville McGhee Tyson

Fri 7/21

1 stop6h 07m

Panama City Tocumen Intl

Thu 7/27

1 stop8h 14m

Knoxville McGhee TysonPanama City Tocumen Intl

TYS - PTY

TYSPTY

Knoxville McGhee Tyson

Wed 6/21

1 stop7h 09m

Panama City Tocumen Intl

Wed 6/28

1 stop8h 38m

Knoxville McGhee TysonPanama City Tocumen Intl

TYS - PTY

TYSPTY

Knoxville McGhee Tyson

Tue 6/20

2 stops18h 28m

Panama City Tocumen Intl

Tue 6/27

2 stops21h 02m

Knoxville McGhee TysonPanama City Tocumen Intl

TYS - PTY

TYSPTY

Knoxville McGhee Tyson

Mon 7/10

2 stops19h 14m

Panama City Tocumen Intl

Wed 7/19

2 stops20h 24m

Knoxville McGhee TysonPanama City Tocumen Intl

TYS - PTY

TYSPTY

Knoxville McGhee Tyson

Tue 6/20

1 stop7h 17m

Panama City Tocumen Intl

Tue 6/27

1 stop25h 10m

Knoxville McGhee TysonPanama City Tocumen Intl

TYS - PTY

TYSPTY

Knoxville McGhee Tyson

Mon 7/10

Nonstop4h 44m

Panama City Tocumen Intl

Wed 7/19

Nonstop2h 44m

Knoxville McGhee TysonPanama City Tocumen Intl

TYS - PTY

TYSPTY

Knoxville McGhee Tyson

Wed 6/21

1 stop11h 31m

Panama City Tocumen Intl

Wed 6/28

1 stop11h 31m

Flights are sorted by cheapest first

Deals found on 5/24

Reviews of Airlines Servicing Panama City

To help decide which airline to fly from Knoxville to Panama City, see what other customers have to say about Delta, American Airlines and Undisclosed Carrier. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
2,341 reviews

Crew

8.5

Comfort

7.9

Overall

8.0

Entertainment

7.8

Food

7.2

Boarding

8.1

Reviews

1 / 10

When everything runs smoothly you barely even think about it. That’s how our flight went.

Delta
8.0
Very good
2,341 reviews
Delta
8.0
Very good
2,341 reviews

Crew

8.5

Comfort

7.9

Overall

8.0

Entertainment

7.8

Food

7.2

Boarding

8.1

Reviews

1 / 10

When everything runs smoothly you barely even think about it. That’s how our flight went.

American Airlines
7.4
Good
2,147 reviews
Delta
8.0
Very good
2,341 reviews

Crew

8.5

Comfort

7.9

Overall

8.0

Entertainment

7.8

Food

7.2

Boarding

8.1

Reviews

1 / 10

When everything runs smoothly you barely even think about it. That’s how our flight went.

Copa Airlines
7.2
Good
300 reviews
Delta
8.0
Very good
2,341 reviews

Crew

8.5

Comfort

7.9

Overall

8.0

Entertainment

7.8

Food

7.2

Boarding

8.1

Reviews

1 / 10

When everything runs smoothly you barely even think about it. That’s how our flight went.

Avianca
7.1
Good
713 reviews
Delta
8.0
Very good
2,341 reviews

Crew

8.5

Comfort

7.9

Overall

8.0

Entertainment

7.8

Food

7.2

Boarding

8.1

Reviews

1 / 10

When everything runs smoothly you barely even think about it. That’s how our flight went.

Related info for your journey

Useful info, stats and facts about Knoxville to Panama City flights.

Top 3 airlines flying from Knoxville to Panama City

The chart below displays the airlines Cheapflights users traveling from Knoxville to Panama City choose most often. Cheapest and average prices are based on aggregated data from the past 12 months.
AirlineCheapestAverageFlexibilityOn-timeCOVID-19 safety
American AirlinesCheapest$483Average$666FlexibilityNo cancel feeOn-time71%COVID-19 safety
Search American Airlines flights
United AirlinesCheapest$553Average$729FlexibilityNo cancel feeOn-time69%COVID-19 safety
Search United Airlines flights
DeltaCheapest$561Average$692FlexibilityNo cancel feeOn-timeN/ACOVID-19 safety
Search Delta flights
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