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Cheap flights from Knoxville (TYS) to Panama from $305

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/7. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
TYS — PTY
May 11 — May 181
From?
To?
Sat 5/11
Sat 5/18
1 adult, Economy
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What is the cheapest month to fly from Knoxville to Panama?

September can be a great time to fly to Panama from Knoxville with a flight ticket averaging about $545. Cheapflights users have found deals in the month of September for as cheap as $434. The most expensive prices can be found in the month of December.

When is the cheapest time to fly from Knoxville to Panama (TYS - PA)?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Knoxville to Panama as you normally would.

Cheap American Airlines flights from Knoxville to Panama

Explore cheap flight options specifically provided by American Airlines for the route between Knoxville and Panama. Find affordable fares and compare prices with other airlines to secure the best deal for your journey. Over the last 7 days, Cheapflights users made 2,719,943 searches. Data last updated May 6, 2024.
Take a peek at the cheapest American Airlines flights we've detected traveling from Knoxville to Panama. Come back soon if you're not finding the exact deal you're looking for.
Sat 9/76:25 pmTYS - PTY
2 stops19h 08mAmerican Airlines
Wed 9/111:55 pmPTY - TYS
2 stops19h 19mAmerican Airlines
Deal found 5/5$305
Sat 9/76:20 pmTYS - PTY
2 stops19h 13mAmerican Airlines
Wed 9/111:55 pmPTY - TYS
2 stops19h 19mAmerican Airlines
Deal found 5/5$436
Mon 5/137:15 pmTYS - PTY
2 stops18h 45mAmerican Airlines
Sat 8/101:46 pmPTY - TYS
1 stop9h 13mAmerican Airlines
Deal found 5/5$580
Sat 7/206:25 pmTYS - PTY
2 stops20h 42mAmerican Airlines
Sat 7/271:20 pmPTY - TYS
2 stops20h 12mAmerican Airlines
Deal found 5/5$586
Mon 5/137:15 pmTYS - PTY
2 stops18h 45mAmerican Airlines
Sat 8/103:14 pmPTY - TYS
1 stop7h 45mAmerican Airlines
Deal found 5/6$620
Mon 5/137:15 pmTYS - PTY
2 stops18h 45mAmerican Airlines
Sat 8/103:14 pmPTY - TYS
2 stops22h 09mAmerican Airlines
Deal found 5/5$636
Mon 5/137:15 pmTYS - PTY
2 stops18h 45mAmerican Airlines
Sat 8/103:14 pmPTY - TYS
2 stops20h 00mAmerican Airlines
Deal found 5/6$658
Tue 6/185:12 amTYS - PTY
2 stops10h 08mAmerican Airlines
Wed 6/193:10 pmPTY - TYS
2 stops18h 41mAmerican Airlines
Deal found 5/5$784
Sun 6/95:17 pmTYS - PTY
2 stops22h 03mAmerican Airlines
Fri 6/143:10 pmPTY - TYS
2 stops18h 47mAmerican Airlines
Deal found 5/5$1,899

Cheap United Airlines flights from Knoxville to Panama

Explore cheap flight options specifically provided by United Airlines for the route between Knoxville and Panama. Find affordable fares and compare prices with other airlines to secure the best deal for your journey. Over the last 7 days, Cheapflights users made 2,719,943 searches. Data last updated May 6, 2024.
To aid your search, here are some of the cheapest United Airlines flights we've found from Knoxville to Panama. Ensure the flight price, dates, time, and airline match your criteria before you book.
Sat 9/79:25 amTYS - PTY
1 stop10h 12mUnited Airlines
Wed 9/1110:00 amPTY - TYS
1 stop12h 30mUnited Airlines
Deal found 5/5$382
Mon 5/137:00 amTYS - PTY
1 stop8h 19mUnited Airlines
Sat 8/107:55 amPTY - TYS
1 stop11h 13mUnited Airlines
Deal found 5/6$611

Cheap Knoxville to Panama flights in May & June 2024

Find cheap flight options from Knoxville to Panama specifically for the months of May and June 2024. Explore affordable fares based on user searches. Over the last 7 days, Cheapflights users made 2,719,943 searches. Prices were last updated on May 6, 2024.
Scroll through some of the best deals on flights from Knoxville to Panama in 2024. Check back soon for alternative fares.
Tue 6/1810:00 amTYS - PTY
2 stops11h 45mMultiple Airlines
Wed 6/1912:10 pmPTY - TYS
1 stop22h 17mMultiple Airlines
Deal found 5/5$507
Mon 5/137:15 pmTYS - PTY
2 stops18h 45mAmerican Airlines
Sat 8/101:46 pmPTY - TYS
1 stop9h 13mAmerican Airlines
Deal found 5/5$580
Tue 6/1810:00 amTYS - PTY
1 stop11h 25mMultiple Airlines
Wed 6/1912:10 pmPTY - TYS
1 stop22h 17mMultiple Airlines
Deal found 5/5$601
Mon 5/137:00 amTYS - PTY
1 stop8h 19mUnited Airlines
Sat 8/107:55 amPTY - TYS
1 stop11h 13mUnited Airlines
Deal found 5/6$611
Mon 5/137:15 pmTYS - PTY
2 stops18h 45mAmerican Airlines
Sat 8/103:14 pmPTY - TYS
1 stop7h 45mAmerican Airlines
Deal found 5/6$620
Mon 5/137:15 pmTYS - PTY
2 stops18h 45mAmerican Airlines
Sat 8/103:14 pmPTY - TYS
2 stops22h 09mAmerican Airlines
Deal found 5/5$636
Mon 5/137:15 pmTYS - PTY
2 stops18h 45mAmerican Airlines
Sat 8/103:14 pmPTY - TYS
2 stops20h 00mAmerican Airlines
Deal found 5/6$658
Tue 6/185:12 amTYS - PTY
2 stops10h 08mAmerican Airlines
Wed 6/193:10 pmPTY - TYS
2 stops18h 41mAmerican Airlines
Deal found 5/5$784
Sun 6/95:17 pmTYS - PTY
2 stops22h 03mAmerican Airlines
Fri 6/143:10 pmPTY - TYS
2 stops18h 47mAmerican Airlines
Deal found 5/5$1,899

Knoxville to Panama 2024 flight deals

Discover exclusive flight deals for travel between Knoxville and Panama in 2024. Find excellent offers based on user searches. Over the last 7 days, Cheapflights users made 2,719,943 searches. Data last updated May 6, 2024.
Scroll through some of the best deals on flights from Knoxville to Panama in 2024. Check back soon for alternative fares.
Sat 9/76:25 pmTYS - PTY
2 stops19h 08mAmerican Airlines
Wed 9/111:55 pmPTY - TYS
2 stops19h 19mAmerican Airlines
Deal found 5/5$305
Sat 9/79:25 amTYS - PTY
1 stop10h 12mUnited Airlines
Wed 9/1110:00 amPTY - TYS
1 stop12h 30mUnited Airlines
Deal found 5/5$382
Sat 9/76:20 pmTYS - PTY
2 stops19h 13mAmerican Airlines
Wed 9/111:55 pmPTY - TYS
2 stops19h 19mAmerican Airlines
Deal found 5/5$436
Sat 7/205:20 amTYS - PTY
1 stop8h 35mDelta
Sat 7/272:25 pmPTY - TYS
1 stop8h 28mDelta
Deal found 5/5$458
Tue 6/1810:00 amTYS - PTY
2 stops11h 45mMultiple Airlines
Wed 6/1912:10 pmPTY - TYS
1 stop22h 17mMultiple Airlines
Deal found 5/5$507
Sat 7/205:37 pmTYS - PTY
2 stops28h 08mMultiple Airlines
Sat 7/2712:10 pmPTY - TYS
1 stop9h 24mMultiple Airlines
Deal found 5/5$576
Mon 5/137:15 pmTYS - PTY
2 stops18h 45mAmerican Airlines
Sat 8/101:46 pmPTY - TYS
1 stop9h 13mAmerican Airlines
Deal found 5/5$580
Sat 7/206:25 pmTYS - PTY
2 stops20h 42mAmerican Airlines
Sat 7/271:20 pmPTY - TYS
2 stops20h 12mAmerican Airlines
Deal found 5/5$586
Tue 6/1810:00 amTYS - PTY
1 stop11h 25mMultiple Airlines
Wed 6/1912:10 pmPTY - TYS
1 stop22h 17mMultiple Airlines
Deal found 5/5$601

Knoxville to Panama flights leaving soon

Find last-minute flight options from Knoxville to Panama for spontaneous travel. Discover available flights and compare prices based on user searches. Secure great deals and offers for spontaneous trips with quick booking options. Over the last 7 days, Cheapflights users made 2,719,943 searches. Data last updated May 6, 2024.
Check out these flights departing soon from Knoxville to Panama. It's wise to confirm all flight details are correct before booking.
Mon 5/137:15 pmTYS - PTY
2 stops18h 45mAmerican Airlines
Sat 8/101:46 pmPTY - TYS
1 stop9h 13mAmerican Airlines
Deal found 5/5$580
Mon 5/137:00 amTYS - PTY
1 stop8h 19mUnited Airlines
Sat 8/107:55 amPTY - TYS
1 stop11h 13mUnited Airlines
Deal found 5/6$611
Mon 5/137:15 pmTYS - PTY
2 stops18h 45mAmerican Airlines
Sat 8/103:14 pmPTY - TYS
1 stop7h 45mAmerican Airlines
Deal found 5/6$620
Mon 5/137:15 pmTYS - PTY
2 stops18h 45mAmerican Airlines
Sat 8/103:14 pmPTY - TYS
2 stops22h 09mAmerican Airlines
Deal found 5/5$636
Mon 5/137:15 pmTYS - PTY
2 stops18h 45mAmerican Airlines
Sat 8/103:14 pmPTY - TYS
2 stops20h 00mAmerican Airlines
Deal found 5/6$658

Find flights from Knoxville to Panama within your budget

Customize your flight search to find flights from Knoxville to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,719,943 searches. Data last updated May 6, 2024.

Fly from

Any airport

Fly to

Any airport

Budget

$305 - $784

Route

Depart

Return

Price

Knoxville McGhee TysonPanama City Tocumen Intl

TYS - PTY

TYSPTY

Knoxville McGhee Tyson

Sat 9/7

2 stops19h 08m

Panama City Tocumen Intl

Wed 9/11

2 stops19h 19m

$305

Knoxville McGhee TysonPanama City Tocumen Intl

TYS - PTY

TYSPTY

Knoxville McGhee Tyson

Sat 9/7

1 stop10h 12m

Panama City Tocumen Intl

Wed 9/11

1 stop12h 30m

$382

Knoxville McGhee TysonPanama City Tocumen Intl

TYS - PTY

TYSPTY

Knoxville McGhee Tyson

Sat 9/7

2 stops19h 13m

Panama City Tocumen Intl

Wed 9/11

2 stops19h 19m

$436

Knoxville McGhee TysonPanama City Tocumen Intl

TYS - PTY

TYSPTY

Knoxville McGhee Tyson

Sat 7/20

1 stop8h 35m

Panama City Tocumen Intl

Sat 7/27

1 stop8h 28m

$458

Knoxville McGhee TysonPanama City Tocumen Intl

TYS - PTY

TYSPTY

Knoxville McGhee Tyson

Tue 6/18

2 stops11h 45m

Panama City Tocumen Intl

Wed 6/19

1 stop22h 17m

$507

Knoxville McGhee TysonPanama City Tocumen Intl

TYS - PTY

TYSPTY

Knoxville McGhee Tyson

Sat 7/20

2 stops28h 08m

Panama City Tocumen Intl

Sat 7/27

1 stop9h 24m

$576

Knoxville McGhee TysonPanama City Tocumen Intl

TYS - PTY

TYSPTY

Knoxville McGhee Tyson

Sat 7/20

2 stops20h 42m

Panama City Tocumen Intl

Sat 7/27

2 stops20h 12m

$586

Knoxville McGhee TysonPanama City Tocumen Intl

TYS - PTY

TYSPTY

Knoxville McGhee Tyson

Tue 6/18

1 stop11h 25m

Panama City Tocumen Intl

Wed 6/19

1 stop22h 17m

$601

Knoxville McGhee TysonPanama City Tocumen Intl

TYS - PTY

TYSPTY

Knoxville McGhee Tyson

Tue 6/18

2 stops10h 08m

Panama City Tocumen Intl

Wed 6/19

2 stops18h 41m

$784

Flights are sorted by cheapest first

Deals found on 5/5

No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated May 6, 2024.
See what other customers who have flown with American Airlines and United Airlines from Knoxville to Panama have to say. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.1
Very good
10,826 reviews
Check prices

Crew

8.6

Overall

8.1

Entertainment

8.0

Boarding

8.2

Comfort

7.9

Food

7.4

Reviews

1 / 10

Bad experience with the staff boarding the gate. I couldn’t board with my carry on, personal item and a funny bag. I had to put my passport inside my pockets and put the funny bag inside the personal item. Then after passing the staff pull out everything again.

Delta
8.1
Very good
10,826 reviews
Delta
8.1
Very good
10,826 reviews
Check prices

Crew

8.6

Overall

8.1

Entertainment

8.0

Boarding

8.2

Comfort

7.9

Food

7.4

Reviews

1 / 10

Bad experience with the staff boarding the gate. I couldn’t board with my carry on, personal item and a funny bag. I had to put my passport inside my pockets and put the funny bag inside the personal item. Then after passing the staff pull out everything again.

United Airlines
7.4
Good
11,118 reviews
Delta
8.1
Very good
10,826 reviews
Check prices

Crew

8.6

Overall

8.1

Entertainment

8.0

Boarding

8.2

Comfort

7.9

Food

7.4

Reviews

1 / 10

Bad experience with the staff boarding the gate. I couldn’t board with my carry on, personal item and a funny bag. I had to put my passport inside my pockets and put the funny bag inside the personal item. Then after passing the staff pull out everything again.

American Airlines
7.3
Good
14,713 reviews
Delta
8.1
Very good
10,826 reviews
Check prices

Crew

8.6

Overall

8.1

Entertainment

8.0

Boarding

8.2

Comfort

7.9

Food

7.4

Reviews

1 / 10

Bad experience with the staff boarding the gate. I couldn’t board with my carry on, personal item and a funny bag. I had to put my passport inside my pockets and put the funny bag inside the personal item. Then after passing the staff pull out everything again.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Panama?

    For a flight from Knoxville to Panama, you will be flying from McGhee Tyson. Knoxville McGhee Tyson (TYS) is just 11.3 mi from the center of the city.

  • Can I find flights from Knoxville to Panama for under $400 on Cheapflights?

    Yes, there are multiple flights from Knoxville to Panama for under $400. The cheapest flight booked recently is on American Airlines for just $305, but on average you can expect to pay $653.

  • Are there last-minute flights available from Knoxville to Panama for under $600?

    There are currently 5+ open flights from Knoxville to Panama within the next 7 days for less than $600.

  • What are the most popular airlines that fly from Knoxville to Panama?

    Before booking your flight from Knoxville to Panama check out the most popular airlines for this route: American Airlines, Delta or United Airlines.

  • What does TYS to PTY mean?

    TYS and PTY are unique codes to identify airports used in the aviation industry. They are defined by IATA (International Air Transport Association) and are commonly called IATA codes. TYS to PTY refers to a flight route from Knoxville McGhee Tyson Airport to Panama City Tocumen Intl Airport. This flight route has multiple associated airports, so we think it might be helpful to learn the name and codes of them as well. They are Panama City Marcos A. Gelabert Intl Airport (PAC), Bocas Del Toro Airport (BOC), David Enrique Malek Airport (DAV), Panama City Panamá Pacifico Airport (BLB), Pedasí Capt. J. Montenegro Airport (PDM).

  • Can I find deals for flights from Knoxville to Panama that include extra baggage allowance?

    The amount of baggage you can bring on your Knoxville to Panama flight depends on the airline and the type of fare you've chosen. After entering your flight details, you'll be able to view the specific baggage policies for each deal in the search results. Keep in mind that certain deals may offer additional baggage allowance.

  • Can I find deals on flights from Knoxville to Panama with specific airlines?

    Yes, Cheapflights allows you to browse and filter Knoxville to Panama flight deals by airline. After entering your origin and destination, use the available filters to view flights offered by airlines.

  • Can I find deals for flights from Knoxville to Panama that include hotel bookings?

    Yes. In addition to deals on Knoxville to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Panama.

  • Can I find deals for business class flights from Knoxville to Panama?

    Yes. Cheapflights offers flight deals from Knoxville to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • Can I find deals for flights from Knoxville to Panama that allow pets onboard?

    Many airlines flying from Knoxville to Panama offer the option to travel with pets. After selecting a flight deal, you can find more information about the airline's pet policy on their official website or by contacting the airline directly. Please note that additional fees and restrictions may apply.

  • Can I find deals on last-minute flights from Knoxville to Panama?

    Yes, you can often find last-minute deals on Knoxville to Panama flights on Cheapflights. However, these deals can vary and may not always be available. We recommend checking back frequently or signing up for price alerts for the most up-to-date deals.

  • How recently were the Knoxville to Panama flight deals updated?

    The Knoxville to Panama flight deals you see on this page were last updated on 5/6.

See more FAQs

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Alternative routes for Knoxville to Panama
See prices for flight routes from nearby airports that may be better suited for you.

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Top 3 airlines flying from Knoxville to Panama

Discover the top 3 airlines that operate flights from Knoxville to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,719,943 searches. Data last updated May 6, 2024.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$281Average$397FlexibilityNo cancel feeOn-time69%
Search United Airlines flights
American AirlinesCheapest$312Average$569FlexibilityNo cancel feeOn-time71%
Search American Airlines flights
DeltaCheapest$413Average$501FlexibilityNo cancel feeOn-timeN/A
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Search flights from Knoxville to Panama by cabin class

Find flights from Knoxville to Panama, based on your preferred cabin class, be it economy, premium economy, business, or first class.
First Class
Business Class
Prem Econ Class
Economy Class

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Fly with Cheapflights

Find the best flight deals on Cheapflights, where travelers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Knoxville to Panama?

When you search for this flight from Knoxville to Panama, Cheapflights searches on 900+ travel sites to save you time finding great flight deals online. Additionally, we offer filter features so you can choose a preferred cabin class or airline, see different price ranges, and much more so you can book the flight for you.

Why should you use Cheapflights to find cheap flight tickets from Knoxville to Panama?

Cheapflights simply makes it quick and affordable to book flights from Knoxville to Panama by bringing together all flight options from hundreds of airlines and agencies online — and put it in one place for you to choose from. Plus, Cheapflights is 100% free to use for all.

Can Cheapflights find flights from Knoxville to Panama with no change fees?

Users can book flights with no change fees policies with our dedicated filters. Book flights from Knoxville to Panama flexibly with Cheapflights today.

Can Cheapflights notify me if prices for flights from Knoxville to Panama become cheaper?

Of course! You can now track prices for flights from Knoxville to Panama and get an alert from Cheapflights when they change. Have a valid email address ready and click the bell icon next to the flight deals above to set up your price alerts.

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