$212+ Cheap flights from Knoxville (TYS) to Guatemala City (GUA)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/27. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — GUA
jul. 16 — jul. 231
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Knoxville to Guatemala City with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Knoxville to Guatemala City
Cheapest
Best
Last-minute
One-way
Cheapest flights from Knoxville to Guatemala CityExplore the most affordable flight options available from Knoxville to Guatemala City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on junio 16, 2026.
Explore the most affordable flight options available from Knoxville to Guatemala City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on junio 16, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 8/286:27 pm
TYS
- GUA
1 stop22h 15m
Multiple Airlines
sáb. 9/53:47 pm
GUA
- TYS
1 stop23h 34m
Multiple Airlines
Deal found 6/11![Multiple Airlines logo]()
$472
This Kiwi.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 7/107:20 pm
TYS
- GUA
1 stop20h 22m
Multiple Airlines
vie. 7/172:47 pm
GUA
- TYS
1 stop6h 46m
Multiple Airlines
Deal found 6/12![Multiple Airlines logo]()
$530
This Kiwi.com deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 7/137:20 pm
TYS
- GUA
1 stop20h 06m
Multiple Airlines
lun. 7/202:47 pm
GUA
- TYS
1 stop6h 46m
Multiple Airlines
Deal found 6/13![Multiple Airlines logo]()
$531
This American Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 10/65:08 am
TYS
- GUA
2 stops15h 07m
American Airlines
vie. 10/301:20 pm
GUA
- TYS
2 stops17h 02m
American Airlines
Deal found 6/12![American Airlines logo]()
$629
This Avianca deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 8/272:21 pm
TYS
- GUA
2 stops10h 49m
Multiple Airlines
sáb. 9/58:15 pm
GUA
- TYS
2 stops12h 22m
Multiple Airlines
Deal found 6/11![Multiple Airlines logo]()
$630
This United Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 8/277:00 am
TYS
- GUA
2 stops11h 37m
United Airlines
vie. 9/41:30 am
GUA
- TYS
1 stop8h 22m
United Airlines
Deal found 6/11![United Airlines logo]()
$688
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 8/276:57 am
TYS
- GUA
2 stops14h 37m
American Airlines
sáb. 9/56:00 am
GUA
- TYS
2 stops15h 18m
American Airlines
Deal found 6/11![American Airlines logo]()
$692
This Delta deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 11/85:30 am
TYS
- GUA
1 stop8h 00m
Delta
jue. 11/122:10 pm
GUA
- TYS
1 stop6h 35m
Delta
Deal found 6/15![Delta logo]()
$703
Best flights from Knoxville to Guatemala CityDiscover carefully curated flight deals from Knoxville to Guatemala City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated junio 16, 2026.
Discover carefully curated flight deals from Knoxville to Guatemala City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated junio 16, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 8/286:27 pm
TYS
- GUA
1 stop22h 15m
Multiple Airlines
sáb. 9/53:47 pm
GUA
- TYS
1 stop23h 34m
Multiple Airlines
Deal found 6/11![Multiple Airlines logo]()
$472
This American Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 10/67:13 am
TYS
- GUA
1 stop5h 42m
American Airlines
vie. 10/301:20 pm
GUA
- TYS
1 stop8h 15m
American Airlines
Deal found 6/12![American Airlines logo]()
$668
This United Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 8/277:00 am
TYS
- GUA
2 stops11h 37m
United Airlines
vie. 9/41:30 am
GUA
- TYS
1 stop8h 22m
United Airlines
Deal found 6/11![United Airlines logo]()
$688
This Delta deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 11/85:30 am
TYS
- GUA
1 stop8h 00m
Delta
jue. 11/122:10 pm
GUA
- TYS
1 stop6h 35m
Delta
Deal found 6/15![Delta logo]()
$703
This Avianca deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 8/272:21 pm
TYS
- GUA
2 stops10h 49m
Multiple Airlines
sáb. 9/58:15 pm
GUA
- TYS
2 stops12h 22m
Multiple Airlines
Deal found 6/11![Multiple Airlines logo]()
$630
This American Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 8/276:00 am
TYS
- GUA
1 stop15h 34m
American Airlines
sáb. 9/56:00 am
GUA
- TYS
1 stop11h 10m
American Airlines
Deal found 6/14![American Airlines logo]()
$688
This Kiwi.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 7/108:19 pm
TYS
- GUA
2 stops41h 36m
Multiple Airlines
vie. 7/172:47 pm
GUA
- TYS
1 stop6h 46m
Multiple Airlines
Deal found 6/12![Multiple Airlines logo]()
$703
This American Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 11/87:38 am
TYS
- GUA
2 stops13h 36m
American Airlines
jue. 11/127:00 am
GUA
- TYS
1 stop8h 37m
American Airlines
Deal found 6/14![American Airlines logo]()
$721
This American Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 9/186:15 am
TYS
- GUA
1 stop6h 41m
American Airlines
sáb. 9/1911:56 am
GUA
- TYS
2 stops18h 34m
American Airlines
Deal found 6/12![American Airlines logo]()
$726
Last-minute flights from Knoxville to Guatemala CityDiscover last-minute flight deals from Knoxville to Guatemala City. Data last updated junio 16, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to Guatemala City. Data last updated junio 16, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 6/187:15 am
TYS
- GUA
1 stop6h 10m
United Airlines
sáb. 6/2711:55 pm
GUA
- TYS
1 stop8h 47m
United Airlines
Deal found 6/11![United Airlines logo]()
$926
This Ovago deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 6/187:15 am
TYS
- GUA
1 stop11h 22m
Multiple Airlines
sáb. 6/2712:26 pm
GUA
- TYS
2 stops20h 16m
Multiple Airlines
Deal found 6/11![Multiple Airlines logo]()
$1,005
This Kiwi.com deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 6/2210:03 pm
TYS
- GUA
2 stops38h 47m
Multiple Airlines
dom. 7/122:47 pm
GUA
- TYS
1 stop28h 28m
Multiple Airlines
Deal found 6/13![Multiple Airlines logo]()
$798
This Kiwi.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 7/107:20 pm
TYS
- GUA
1 stop20h 22m
Multiple Airlines
vie. 7/172:47 pm
GUA
- TYS
1 stop6h 46m
Multiple Airlines
Deal found 6/12![Multiple Airlines logo]()
$530
This United Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 7/101:35 pm
TYS
- GUA
2 stops29h 02m
United Airlines
vie. 7/1711:55 pm
GUA
- TYS
2 stops18h 49m
United Airlines
Deal found 6/12![United Airlines logo]()
$912
This Kiwi.com deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 7/137:20 pm
TYS
- GUA
1 stop20h 06m
Multiple Airlines
lun. 7/202:47 pm
GUA
- TYS
1 stop6h 46m
Multiple Airlines
Deal found 6/13![Multiple Airlines logo]()
$531
This United Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 7/137:15 am
TYS
- GUA
1 stop11h 22m
United Airlines
mar. 7/1411:55 pm
GUA
- TYS
1 stop8h 47m
United Airlines
Deal found 6/11![United Airlines logo]()
$835
This United Airlines deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 7/131:35 pm
TYS
- GUA
2 stops26h 55m
United Airlines
lun. 7/206:15 am
GUA
- TYS
2 stops26h 27m
United Airlines
Deal found 6/13![United Airlines logo]()
$959
One-way flights from Knoxville to Guatemala CitySearch for one-way flight options from Knoxville to Guatemala City. Find affordable one-way fares based on user searches. Data last updated junio 16, 2026.
Search for one-way flight options from Knoxville to Guatemala City. Find affordable one-way fares based on user searches. Data last updated junio 16, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 7/2710:05 pm
TYS
- GUA
1 stop17h 21m
Multiple Airlines
Deal found 6/12![Multiple Airlines logo]()
$212
This Kiwi.com deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 7/317:20 pm
TYS
- GUA
2 stops40h 45m
Multiple Airlines
Deal found 6/13![Multiple Airlines logo]()
$223
This Trip.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 7/74:20 pm
TYS
- GUA
1 stop23h 22m
Multiple Airlines
Deal found 6/12![Multiple Airlines logo]()
$279
This Faresmojo deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Faresmojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 6/277:15 am
TYS
- GUA
1 stop6h 09m
JetBlue
Deal found 6/16![JetBlue logo]()
$408
This American Airlines deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 6/276:00 am
TYS
- GUA
1 stop7h 21m
American Airlines
Deal found 6/13![American Airlines logo]()
$509
This United Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 6/276:00 am
TYS
- GUA
2 stops36h 37m
United Airlines
Deal found 6/12![United Airlines logo]()
$530
Find flight deals from Knoxville to Guatemala City
Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Guatemala City (GUA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated junio 16, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $472 (Kiwi.com) |
One-way from | $212 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to Guatemala City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated junio 16, 2026.
Use the filters below to find and compare flights from Knoxville to Guatemala City that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvilleGuatemala City
TYS - GUA
TYSGUA
Knoxville McGhee Tyson
vie. 8/28
6:27 pm-2:42 pm
1 stop22h 15m
Guatemala City La Aurora
sáb. 9/5
3:47 pm-5:21 pm
1 stop23h 34m
$472
KnoxvilleGuatemala City
TYS - GUA
TYSGUA
Knoxville McGhee Tyson
jue. 8/27
2:21 pm-11:10 pm
2 stops10h 49m
Guatemala City La Aurora
sáb. 9/5
8:15 pm-10:37 am
2 stops12h 22m
$630
Quickest round-trip
KnoxvilleGuatemala City
TYS - GUA
TYSGUA
Knoxville McGhee Tyson
mar. 10/6
7:13 am-10:55 am
1 stop5h 42m
Guatemala City La Aurora
vie. 10/30
1:20 pm-11:35 pm
1 stop8h 15m
$668
KnoxvilleGuatemala City
TYS - GUA
TYSGUA
Knoxville McGhee Tyson
jue. 8/27
7:00 am-4:37 pm
2 stops11h 37m
Guatemala City La Aurora
vie. 9/4
1:30 am-11:52 am
1 stop8h 22m
$688
KnoxvilleGuatemala City
TYS - GUA
TYSGUA
Knoxville McGhee Tyson
jue. 8/27
6:00 am-7:34 pm
1 stop15h 34m
Guatemala City La Aurora
sáb. 9/5
6:00 am-7:10 pm
1 stop11h 10m
$688
KnoxvilleGuatemala City
TYS - GUA
TYSGUA
Knoxville McGhee Tyson
dom. 11/8
5:30 am-12:30 pm
1 stop8h 00m
Guatemala City La Aurora
jue. 11/12
2:10 pm-9:45 pm
1 stop6h 35m
$703
KnoxvilleGuatemala City
TYS - GUA
TYSGUA
Knoxville McGhee Tyson
vie. 7/10
8:19 pm-11:55 am
2 stops41h 36m
Guatemala City La Aurora
vie. 7/17
2:47 pm-11:33 pm
1 stop6h 46m
$703
KnoxvilleGuatemala City
TYS - GUA
TYSGUA
Knoxville McGhee Tyson
dom. 11/8
7:38 am-8:14 pm
2 stops13h 36m
Guatemala City La Aurora
jue. 11/12
7:00 am-4:37 pm
1 stop8h 37m
$721
KnoxvilleGuatemala City
TYS - GUA
TYSGUA
Knoxville McGhee Tyson
vie. 9/18
6:15 am-10:56 am
1 stop6h 41m
Guatemala City La Aurora
sáb. 9/19
11:56 am-8:30 am
2 stops18h 34m
$726
Cheapest one-way
KnoxvilleGuatemala City
TYS - GUA
TYSGUA
Knoxville McGhee Tyson
vie. 7/31
7:20 pm-10:05 am
2 stops40h 45m
$223
Showing 1-10 of 12 resultsSorted by cheapest first
Compare providers for flights from Knoxville to Guatemala City
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Guatemala City in June.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star |
- Most accurate provider: When it comes to deals on Knoxville-Guatemala City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Guatemala City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Guatemala City flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Knoxville-Guatemala City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Guatemala City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Knoxville to Guatemala City
Have a flexible travel schedule? Discover the best time to fly to Guatemala City from Knoxville with our price prediction graph.
TYS-GUA
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Guatemala City
Get insights into the airlines that provide service to Guatemala City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guatemala City. Reviews last updated junio 16, 2026.
Get a feel of what it's like to fly with American Airlines from Knoxville to Guatemala City by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
6.4
Overall
7.1
Entertainment
6.8
Boarding
7.5
Comfort
7.2
Crew
7.9
Reviews
1 / 20
2.0
MediocreAnonymous,Apr 2026
DFW - BDL
Food
6.4
Overall
7.1
Entertainment
6.8
Boarding
7.5
Comfort
7.2
Crew
7.9
Reviews
1 / 20
2.0
MediocreAnonymous,Apr 2026
DFW - BDL
Related info for your journey
Find useful and relevant information for your journey from Knoxville to Guatemala City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Guatemala City?
Book flights to Guatemala City if you plan to visit one of these locationsAntigua
Panajachel
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Guatemala City flight routes
Other flight options
Other flights from Knoxville
Popular flights
Alternative routes for Knoxville to Guatemala City
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Guatemala City by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Knoxville to Guatemala City by cabin class
Find flights from Knoxville to Guatemala City, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Guatemala City
Explore flights to Guatemala City departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on junio 16, 2026.
Knoxville and Guatemala City flights
Browse other Knoxville and Guatemala City flight options. Last updated on junio 16, 2026.
Other flights from Knoxville
Browse through other flights departing from Knoxville. Flights are based on user searches made on Cheapflights and were last updated on junio 16, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from Knoxville to Guatemala City
Discover the top airline that operate flights from Knoxville to Guatemala City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated junio 16, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$509 | Average$626 | FlexibilityNo cancel fee | On-time71% |