$426+ Cheap flights from Knoxville (TYS) to Guatemala
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/29. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — GUA
Nov 18 — Nov 251
Round-trip
1 adult, Economy
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Find cheap flights from Knoxville to Guatemala with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Knoxville to Guatemala
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Cheapest flights from Knoxville to GuatemalaExplore the most affordable flight options available from Knoxville to Guatemala. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 19, 2026.
Explore the most affordable flight options available from Knoxville to Guatemala. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 19, 2026.
This American Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/37:35 pm -
1 stop20h 37m
Thu 12/1011:25 am -
1 stop11h 40m
Deal found 10/18![American Airlines logo]()
$723
This American Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/18:04 pm -
2 stops15h 21m
Tue 12/811:25 am -
1 stop9h 45m
Deal found 10/17![American Airlines logo]()
$756
This Avianca deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/149:45 am -
2 stops14h 20m
Sat 12/58:00 pm -
1 stop17h 53m
Deal found 10/16![Multiple Airlines logo]()
$809
This American Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:00 am -
1 stop7h 04m
Mon 10/192:05 pm -
1 stop6h 54m
Deal found 10/14![American Airlines logo]()
$812
This Avianca deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/149:45 am -
2 stops14h 20m
Sat 12/510:00 am -
2 stops12h 59m
Deal found 10/16![Avianca logo]()
$833
Best flights from Knoxville to GuatemalaDiscover carefully curated flight deals from Knoxville to Guatemala that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 19, 2026.
Discover carefully curated flight deals from Knoxville to Guatemala that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 19, 2026.
This American Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/37:35 pm -
1 stop20h 37m
Thu 12/105:50 am -
2 stops14h 08m
Deal found 10/18![American Airlines logo]()
$727
This Avianca deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/149:45 am -
2 stops14h 20m
Sat 12/58:00 pm -
1 stop17h 53m
Deal found 10/16![Multiple Airlines logo]()
$809
This Avianca deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/145:45 am -
1 stop25h 05m
Sat 12/58:00 pm -
1 stop26h 59m
Deal found 10/15![Avianca logo]()
$855
This United Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/143:45 pm -
1 stop24h 50m
Sat 12/52:48 pm -
1 stop19h 24m
Deal found 10/19![United Airlines logo]()
$901
This American Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:00 am -
1 stop15h 23m
Fri 11/63:10 pm -
1 stop7h 49m
Deal found 10/18![American Airlines logo]()
$895
This Kiwi.com deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/229:04 pm -
2 stops39h 42m
Sun 1/32:56 pm -
1 stop26h 16m
Deal found 10/17![Multiple Airlines logo]()
$901
Last-minute flights from Knoxville to GuatemalaDiscover last-minute flight deals from Knoxville to Guatemala. Data last updated October 19, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to Guatemala. Data last updated October 19, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:00 am -
1 stop15h 23m
Fri 11/63:10 pm -
1 stop7h 49m
Deal found 10/19![American Airlines logo]()
$895
This Avianca deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/149:45 am -
2 stops14h 20m
Sat 12/58:00 pm -
1 stop17h 53m
Deal found 10/16![Multiple Airlines logo]()
$809
This Avianca deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/149:45 am -
2 stops14h 20m
Sat 12/510:00 am -
2 stops12h 59m
Deal found 10/16![Avianca logo]()
$833
This United Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/143:45 pm -
1 stop24h 50m
Sat 12/52:48 pm -
1 stop19h 24m
Deal found 10/19![United Airlines logo]()
$901
This American Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/307:22 pm -
1 stop16h 02m
Mon 12/74:12 pm -
1 stop6h 53m
Deal found 10/16![American Airlines logo]()
$812
One-way flights from Knoxville to GuatemalaSearch for one-way flight options from Knoxville to Guatemala. Find affordable one-way fares based on user searches. Data last updated October 19, 2026.
Search for one-way flight options from Knoxville to Guatemala. Find affordable one-way fares based on user searches. Data last updated October 19, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:30 am -
2 stops16h 19m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![Multiple Airlines logo]()
$426
This Kiwi.com deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/269:42 pm -
3 stops39h 27m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![Multiple Airlines logo]()
$434
This Kiwi.com deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/259:29 pm -
3 stops39h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![Multiple Airlines logo]()
$444
This Avianca deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/287:35 pm -
2 stops15h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![Avianca logo]()
$473
This Kiwi.com deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3012:57 pm -
3 stops26h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![Multiple Airlines logo]()
$486
This FlightHub deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/271:55 pm -
1 stop17h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![Avianca logo]()
$488
This Kiwi.com deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/278:30 am -
3 stops31h 12m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![Multiple Airlines logo]()
$492
This Avianca deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/311:55 pm -
1 stop17h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![Avianca logo]()
$500
This FlightHub deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected ” under the list of providers to see comparable flight deals.
Thu 10/299:45 am -
1 stop22h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![Avianca logo]()
$505
This United Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/285:45 am -
1 stop16h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![United Airlines logo]()
$513
This Avianca deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/269:45 am -
1 stop22h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![Avianca logo]()
$518
Find flight deals from Knoxville to Guatemala
Keep the following information in mind while searching for Knoxville to Guatemala flight deals. Data was last updated October 19, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $655 (American Airlines) |
One-way from | $426 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to Guatemala that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 19, 2026.
Use the filters below to find and compare flights from Knoxville to Guatemala that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvilleGuatemala City
TYS Knoxville McGhee Tyson - GUA Guatemala City La Aurora
TYSGUA
Knoxville McGhee Tyson
Sat 10/31
1:55 pm-5:50 am
1 stop17h 55m
Guatemala City La Aurora
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$500
Quickest round-trip
KnoxvilleGuatemala City
TYS Knoxville McGhee Tyson - GUA Guatemala City La Aurora
TYSGUA
Knoxville McGhee Tyson
Wed 10/28
5:45 am-8:25 pm
1 stop16h 40m
Guatemala City La Aurora
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$513
KnoxvilleGuatemala City
TYS Knoxville McGhee Tyson - GUA Guatemala City La Aurora
TYSGUA
Knoxville McGhee Tyson
Wed 10/28
9:10 am-1:42 pm
3 stops30h 32m
Guatemala City La Aurora
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$570
KnoxvilleGuatemala City
TYS Knoxville McGhee Tyson - GUA Guatemala City La Aurora
TYSGUA
Knoxville McGhee Tyson
Fri 10/30
7:35 pm-6:39 pm
2 stops25h 04m
Guatemala City La Aurora
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$618
KnoxvilleGuatemala City
TYS Knoxville McGhee Tyson - GUA Guatemala City La Aurora
TYSGUA
Knoxville McGhee Tyson
Sun 10/25
5:45 am-8:25 pm
1 stop16h 40m
Guatemala City La Aurora
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$633
KnoxvilleGuatemala City
TYS Knoxville McGhee Tyson - GUA Guatemala City La Aurora
TYSGUA
Knoxville McGhee Tyson
Thu 12/3
7:35 pm-3:12 pm
1 stop20h 37m
Guatemala City La Aurora
Thu 12/10
5:50 am-8:58 pm
2 stops14h 08m
$727
KnoxvilleGuatemala City
TYS Knoxville McGhee Tyson - GUA Guatemala City La Aurora
TYSGUA
Knoxville McGhee Tyson
Sat 11/14
9:45 am-11:05 pm
2 stops14h 20m
Guatemala City La Aurora
Sat 12/5
8:00 pm-2:53 pm
1 stop17h 53m
$809
KnoxvilleGuatemala City
TYS Knoxville McGhee Tyson - GUA Guatemala City La Aurora
TYSGUA
Knoxville McGhee Tyson
Sat 11/14
5:45 am-5:50 am
1 stop25h 05m
Guatemala City La Aurora
Sat 12/5
8:00 pm-11:59 pm
1 stop26h 59m
$855
KnoxvilleGuatemala City
TYS Knoxville McGhee Tyson - GUA Guatemala City La Aurora
TYSGUA
Knoxville McGhee Tyson
Fri 10/30
6:00 am-7:23 pm
1 stop15h 23m
Guatemala City La Aurora
Fri 11/6
3:10 pm-11:59 pm
1 stop7h 49m
$895
KnoxvilleGuatemala City
TYS Knoxville McGhee Tyson - GUA Guatemala City La Aurora
TYSGUA
Knoxville McGhee Tyson
Sat 11/14
3:45 pm-3:35 pm
1 stop24h 50m
Guatemala City La Aurora
Sat 12/5
2:48 pm-11:12 am
1 stop19h 24m
$901
Showing 1-10 of 11 resultsSorted by cheapest first
Best time to book a flight from Knoxville to Guatemala
Have a flexible travel schedule? Discover the best time to fly to Guatemala from Knoxville with our price prediction graph.
TYS-GUA
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Knoxville to Guatemala
TYS-GT0
TYS-GUA
No data available for this route at this time. Please check back soon.
Reviews of airlines servicing Guatemala
Get insights into the airlines that provide service to Guatemala. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guatemala. Reviews last updated October 19, 2026.
Read through reviews of airlines operating flights from Knoxville to Guatemala, such as United Airlines and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Food
6.7
Boarding
7.7
Comfort
7.3
Crew
8.1
Entertainment
7.1
Overall
7.3
Reviews
1 / 20
8.0
ExcellentAsha,Sep 2026
LGA - IAH
Food
6.7
Boarding
7.7
Comfort
7.3
Crew
8.1
Entertainment
7.1
Overall
7.3
Reviews
1 / 20
8.0
ExcellentAsha,Sep 2026
LGA - IAH
Food
6.7
Boarding
7.7
Comfort
7.3
Crew
8.1
Entertainment
7.1
Overall
7.3
Reviews
1 / 20
8.0
ExcellentAsha,Sep 2026
LGA - IAH
Related info for your journey
Find useful and relevant information for your journey from Knoxville to Guatemala. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Knoxville to Guatemala
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Guatemala by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Knoxville to Guatemala by cabin class
Find flights from Knoxville to Guatemala, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Knoxville and Guatemala flights
Browse other Knoxville and Guatemala flight options. Last updated on October 19, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Knoxville to Guatemala
Discover the top 2 airlines that operate flights from Knoxville to Guatemala. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 19, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$509 | Average$812 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$545 | Average$762 | FlexibilityNo cancel fee | On-time69% |