Knoxville

$49+ Cheap flights from Knoxville

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/4. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — ORD
Jun 22 — Jun 291
We work with more than 300 partners to bring you better travel deals

What to know about flights from Knoxville

Discover essential information about flights departing from Knoxville, including flight schedules, destinations, airlines operating at the Knoxville airport, and any specific guidelines or requirements for travelers. Please note that the information is based on the most recent updates available. Data last updated June 17, 2025.

Cheapest one-way flight

$45

Cheapest round-trip flight

$55

Cheapest airline

Allegiant Air

Most popular destination

Atlanta Hartsfield-Jackson (ATL)

Good round-trip deal

$74 or less

Good one-way deal

$39 or less
The cheapest one-way flight from Knoxville McGhee Tyson is currently to Orlando Sanford Intl.
The cheapest round-trip flight from Knoxville McGhee Tyson is currently to Newark.
On average, Allegiant Air currently has the cheapest one-way flight from Knoxville McGhee Tyson (avg. price of $78).
Atlanta Hartsfield-Jackson (ATL) is currently the most popular flight destination from Knoxville McGhee Tyson (average round-trip price of $333).
Price to beat on a round-trip flight from Knoxville McGhee Tyson.
Price to beat on a one-way flight from Knoxville McGhee Tyson.

Find flights from Knoxville

Cheapest flights from Knoxville
Explore the most affordable flight options available from Knoxville. Find the lowest fares based on data from user searches, with prices last updated on June 17, 2025.

Thu 7/103:01 pmTYS - SFB
Nonstop1h 31mAllegiant Air
Thu 7/1710:05 pmSFB - TYS
Nonstop1h 32mAllegiant Air
Deal found 6/16$87
Fri 7/186:00 amTYS - MCO
Nonstop1h 37mAllegiant Air
Mon 7/218:27 amMCO - TYS
Nonstop1h 44mAllegiant Air
Deal found 6/16$93
Mon 7/148:52 amTYS - MCO
1 stop10h 23mMultiple Airlines
Fri 7/188:27 amMCO - TYS
Nonstop1h 44mMultiple Airlines
Deal found 6/16$141
Thu 8/288:36 pmTYS - DEN
Nonstop3h 11mFrontier
Thu 9/42:52 pmDEN - TYS
Nonstop2h 49mFrontier
Deal found 6/16$147
Sun 7/133:54 pmTYS - DEN
Nonstop3h 03mAllegiant Air
Thu 7/315:42 pmDEN - TYS
Nonstop2h 45mAllegiant Air
Deal found 6/15$151
Wed 7/166:05 amTYS - MIA
Nonstop2h 10mAmerican Airlines
Wed 7/2310:05 pmMIA - TYS
Nonstop1h 54mAmerican Airlines
Deal found 6/16$159
Wed 7/3011:55 amTYS - LGA
Nonstop2h 04mAmerican Airlines
Wed 8/69:10 amLGA - TYS
Nonstop2h 19mAmerican Airlines
Deal found 6/15$159
Wed 9/311:26 amTYS - MIA
1 stop7h 16mDelta
Wed 9/2412:05 pmMIA - TYS
1 stop6h 08mDelta
Deal found 6/15$179
Wed 9/106:10 amTYS - LGA
Nonstop2h 04mDelta
Sat 9/132:30 pmLGA - TYS
Nonstop2h 17mDelta
Deal found 6/17$187
Fri 9/127:18 amTYS - ORD
Nonstop2h 04mAmerican Airlines
Mon 9/159:28 amORD - TYS
Nonstop1h 53mAmerican Airlines
Deal found 6/15$189
Wed 9/105:45 amTYS - JFK
1 stop4h 15mDelta
Sat 9/1311:15 amJFK - TYS
1 stop6h 58mDelta
Deal found 6/15$197
Thu 7/175:25 pmTYS - DEN
Nonstop3h 15mMultiple Airlines
Sun 7/205:42 pmDEN - TYS
Nonstop2h 45mMultiple Airlines
Deal found 6/16$201

Find flights from Knoxville within your budget

Find flights departing from Knoxville that match your specified budget. Filter results by price range, allowing you to narrow down options and find flights that fit within your financial constraints. Please note that the search results are based on data from user searches, with fares last updated on June 17, 2025. In the last 7 days, Cheapflights users made a total of 2,558,603 searches

Fly to

O'Hare Intl

Route

Depart

Return

Price

KnoxvilleOrlando

TYS - SFB

TYSSFB

Knoxville McGhee Tyson

Thu 7/10

3:01 pm-4:32 pm

Nonstop1h 31m

Orlando Sanford Intl

Thu 7/17

10:05 pm-11:37 pm

Nonstop1h 32m

$87

KnoxvilleOrlando

TYS - MCO

TYSMCO

Knoxville McGhee Tyson

Fri 7/18

6:00 am-7:37 am

Nonstop1h 37m

Orlando

Mon 7/21

8:27 am-10:11 am

Nonstop1h 44m

$93

KnoxvilleOrlando

TYS - MCO

TYSMCO

Knoxville McGhee Tyson

Mon 7/14

8:52 am-7:15 pm

1 stop10h 23m

Orlando

Fri 7/18

8:27 am-10:11 am

Nonstop1h 44m

$141

KnoxvilleDenver

TYS - DEN

TYSDEN

Knoxville McGhee Tyson

Thu 8/28

8:36 pm-9:47 pm

Nonstop3h 11m

Denver Intl

Thu 9/4

2:52 pm-7:41 pm

Nonstop2h 49m

$147

KnoxvilleDenver

TYS - DEN

TYSDEN

Knoxville McGhee Tyson

Sun 7/13

3:54 pm-4:57 pm

Nonstop3h 03m

Denver Intl

Thu 7/31

5:42 pm-10:27 pm

Nonstop2h 45m

$151

KnoxvilleMiami

TYS - MIA

TYSMIA

Knoxville McGhee Tyson

Wed 7/16

6:05 am-8:15 am

Nonstop2h 10m

Miami

Wed 7/23

10:05 pm-11:59 pm

Nonstop1h 54m

$159

KnoxvilleNew York

TYS - LGA

TYSLGA

Knoxville McGhee Tyson

Wed 7/30

11:55 am-1:59 pm

Nonstop2h 04m

New York LaGuardia

Wed 8/6

9:10 am-11:29 am

Nonstop2h 19m

$159

KnoxvilleMiami

TYS - MIA

TYSMIA

Knoxville McGhee Tyson

Wed 9/3

11:26 am-6:42 pm

1 stop7h 16m

Miami

Wed 9/24

12:05 pm-6:13 pm

1 stop6h 08m

$179

KnoxvilleNew York

TYS - LGA

TYSLGA

Knoxville McGhee Tyson

Wed 9/10

6:10 am-8:14 am

Nonstop2h 04m

New York LaGuardia

Sat 9/13

2:30 pm-4:47 pm

Nonstop2h 17m

$187

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

Fri 9/12

7:18 am-8:22 am

Nonstop2h 04m

Chicago O'Hare Intl

Mon 9/15

9:28 am-12:21 pm

Nonstop1h 53m

$189

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/16

Showing 1-10 of 60 results
1
2
3
...
6

Best time to book a flight from Knoxville

Have a flexible travel schedule? Discover the best time to fly from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Knoxville

Get recent, data-driven insights about flights from Knoxville including ideal travel times, pricing trends, and more.

When is the best time to book a flight from Knoxville?

Use this chart to determine the optimal time to book a round-trip flight from Knoxville to O'Hare Intl. Price data was last updated on June 13, 2025.

To ensure you get the cheapest price possible for a flight from Knoxville, you should look to book at least 42 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Knoxville?

Currently, September is the cheapest month in which you can book a flight from Knoxville (average of $149). Flying from Knoxville in July will prove the most costly (average of $194). There are multiple factors that influence the price of a flight so comparing airlines, departure airports and times can help keep costs down.

When is the cheapest time to fly from Knoxville?

Use this chart to determine the cheapest time to fly round-trip from Knoxville to O'Hare Intl. Price data was last updated on June 15, 2025.

Those who are seeking the cheapest fare on flights departing from Knoxville would be wise to consider leaving during Thursday evenings when prices are typically at their lowest. When considering other options, price-conscious travelers should avoid Monday at noon when fares are usually the most expensive.

Airline reviews for flights from Knoxville

Read reviews and ratings of airlines operating flights from Knoxville. Gain insights into the quality of service, in-flight amenities, customer experiences, and overall satisfaction to choose the best airline for your Knoxville travel. Please note that the reviews are sourced from user searches and were last updated on June 17, 2025. In the last 7 days, Cheapflights users made a total of 2,558,603 searches.
8.0
Very good

Crew

8.5

Entertainment

7.9

Boarding

8.2

Overall

8.0

Food

7.3

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
8.0
Very good
8.0
Very good

Crew

8.5

Entertainment

7.9

Boarding

8.2

Overall

8.0

Food

7.3

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
8.0
Very good

Crew

8.5

Entertainment

7.9

Boarding

8.2

Overall

8.0

Food

7.3

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
8.0
Very good

Crew

8.5

Entertainment

7.9

Boarding

8.2

Overall

8.0

Food

7.3

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
8.0
Very good

Crew

8.5

Entertainment

7.9

Boarding

8.2

Overall

8.0

Food

7.3

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
8.0
Very good

Crew

8.5

Entertainment

7.9

Boarding

8.2

Overall

8.0

Food

7.3

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Airports servicing Knoxville

Fly out of one of these airports located in Knoxville.

Related info for your journey

Access useful and relevant information related to your journey from Knoxville. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated June 17, 2025.
  • What are the most popular destinations to fly to from Knoxville?

    This month, the top selected destinations from Knoxville are Denver, Fort Lauderdale, Chicago. Throughout the year, Denver, Fort Lauderdale, Chicago are some of the top choices made by users flying from Knoxville.

  • What is the cheapest flight from Knoxville to anywhere?

    Users have flown out of Knoxville for as low as $35 to Jacksonville (prices may vary depending on the airline and departure time). On average, users have booked flights for $383 to fly from Knoxville.

  • What are the cheapest airlines flying from Knoxville to anywhere?

    Over the past few days, we've found that Allegiant Air, Frontier, and Avelo Airlines have the cheapest prices from Knoxville. Allegiant Air flights from Knoxville to Austin Bergstrom ($31), Frontier flights from Knoxville to Denver Intl ($38), and Avelo Airlines flights from Knoxville to Tweed-New Haven ($94).

  • What is the cheapest premium economy flight from Knoxville?

    Options for some of the cheapest premium economy flights from Knoxville we have found on Cheapflights are as follows:
    Fly from Knoxville McGhee Tyson to New York LaGuardia Airport starting at $632
    Fly from Knoxville McGhee Tyson to Miami starting at $675
    Fly from Knoxville McGhee Tyson to Charlotte starting at $840
    Fly from Knoxville McGhee Tyson to Denver starting at $906

  • What is the cheapest first class flight from Knoxville?

    If you’re looking for a cheap first-class flight from Knoxville, consider Washington, D.C.. Prices start at $547 so you can fly first-class even on a budget.

  • What is the cheapest month to fly from Knoxville?

    September is currently the cheapest month to fly from Knoxville. At this moment in time July is the most expensive month. These prices are determined by multiple factors and booking in advance can help keep costs down if your schedule is not as flexible.

  • Where are the cheapest places to fly to from Knoxville?

    Check out the cheapest flights from Knoxville to embark to:
    Fly from Knoxville to Orlando from $58 round trip
    Fly from Knoxville to Chicago from $58 round trip
    Fly from Knoxville to Washington, D.C. from $80 round trip
    Fly from Knoxville to Houston from $83 round trip
    Fly from Knoxville to Fort Lauderdale from $86 round trip

See more FAQs

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.