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$84+ Cheap flights from Knoxville to Key West (TYS - EYW)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/24. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — EYW
Dec 5 — Dec 121
Fri 12/5
Fri 12/12
1 adult, Economy
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Cheapflights Tip: The best prices from Knoxville McGhee Tyson to Key West are usually found in November or October, booked 15 days in advance, depart on a Monday or Wednesday and return on a Wednesday

Cheap flight deals from Knoxville to Key West

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Key West (EYW). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 5, 2025.

Most accurate provider

Mytrip
3 stars

Most trusted provider

Mytrip
3 stars

Round-trip from

$84
(Kiwi.com)

Popular in

April

Cheapest in

November

Average price

$157

Good round-trip deal

$120 or less
Provider with most accurate pricing for Knoxville McGhee Tyson-Key West flight deals.
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Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Key West flights.
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From Knoxville McGhee Tyson to Key West
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Highest demand for flights based on searches. 13% potential increase in price ($47 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($12 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Price to beat on a round-trip flight from Knoxville McGhee Tyson to Key West.
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Find flight deals from Knoxville to Key West

Cheapest flights from Knoxville to Key West
Explore the most affordable flight options available from Knoxville to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 5, 2025.

This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/2412:12 pmTYS - EYW
Nonstop2h 11mAllegiant Air
Wed 11/2610:01 amEYW - TYS
Nonstop2h 15mAllegiant Air
Deal found 11/3$84
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/1511:22 amTYS - EYW
Nonstop2h 11mAllegiant Air
Wed 12/248:45 pmEYW - TYS
Nonstop2h 15mAllegiant Air
Deal found 11/3$109
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1911:32 amTYS - EYW
Nonstop2h 11mAllegiant Air
Wed 12/248:45 pmEYW - TYS
Nonstop2h 15mAllegiant Air
Deal found 11/4$111
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/208:00 amTYS - EYW
1 stop13h 36mAllegiant Air
Mon 11/243:13 pmEYW - TYS
Nonstop2h 15mAllegiant Air
Deal found 11/4$178
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/235:49 pmTYS - EYW
2 stops40h 30mMultiple Airlines
Wed 11/2610:01 amEYW - TYS
Nonstop2h 15mMultiple Airlines
Deal found 11/4$198

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 5, 2025.
Use the filters below to find and compare flights from Knoxville to Key West that are best for you.

Fly from

Knoxville

Fly to

Key West

Route

Depart

Return

Price

KnoxvilleKey West

TYS - EYW

TYSEYW

Knoxville McGhee Tyson

Fri 12/19

11:32 am-1:43 pm

Nonstop2h 11m

Key West

Wed 12/24

8:45 pm-11:00 pm

Nonstop2h 15m

$113

KnoxvilleKey West

TYS - EYW

TYSEYW

Knoxville McGhee Tyson

Thu 11/20

8:00 am-9:36 pm

1 stop13h 36m

Key West

Mon 11/24

3:13 pm-5:28 pm

Nonstop2h 15m

$178

KnoxvilleKey West

TYS - EYW

TYSEYW

Knoxville McGhee Tyson

Sun 2/22

9:32 pm-1:30 pm

1 stop15h 58m

Key West

Fri 2/27

11:01 am-1:16 pm

Nonstop2h 15m

$220

KnoxvilleKey West

TYS - EYW

TYSEYW

Knoxville McGhee Tyson

Sun 2/22

9:00 am-2:19 pm

1 stop5h 19m

Key West

Fri 2/27

11:01 am-1:16 pm

Nonstop2h 15m

$221

KnoxvilleKey West

TYS - EYW

TYSEYW

Knoxville McGhee Tyson

Fri 12/19

11:32 am-1:43 pm

Nonstop2h 11m

Key West

Wed 12/24

2:30 pm-3:16 pm

3 stops24h 46m

$237

KnoxvilleKey West

TYS - EYW

TYSEYW

Knoxville McGhee Tyson

Fri 12/5

11:28 am-1:39 pm

Nonstop2h 11m

Key West

Tue 12/9

11:45 am-12:03 pm

2 stops24h 18m

$247

KnoxvilleKey West

TYS - EYW

TYSEYW

Knoxville McGhee Tyson

Fri 2/6

5:14 pm-9:47 pm

1 stop4h 33m

Key West

Mon 2/9

7:45 pm-11:59 pm

1 stop4h 14m

$249

KnoxvilleKey West

TYS - EYW

TYSEYW

Knoxville McGhee Tyson

Thu 2/19

4:15 pm-10:59 pm

2 stops6h 44m

Key West

Mon 2/23

7:54 pm-11:59 pm

1 stop4h 05m

$254

KnoxvilleKey West

TYS - EYW

TYSEYW

Knoxville McGhee Tyson

Tue 12/30

6:55 am-9:42 pm

1 stop14h 47m

$123

KnoxvilleKey West

TYS - EYW

TYSEYW

Knoxville McGhee Tyson

Wed 11/19

6:04 pm-9:36 pm

1 stop27h 32m

$134

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/3

Showing 1-10 of 13 results
1
2

Compare providers for flights from Knoxville to Key West

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Key West in November.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
MytripPrice Accuracy3 starsTrust Score*3 stars
PricelinePrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Knoxville-Key West flights, users find the pricing of Mytrip to be most consistent on Cheapflights vs. Mytrip Users can find the same prices on Knoxville-Key West flight deals on Cheapflights vs. Mytrip >95% of the time. Price accuracy is based on data collected from Knoxville-Key West flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Knoxville-Key West flights, Cheapflights users trust Mytrip the most. Mytrip has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Key West flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to Key West

Have a flexible travel schedule? Discover the best time to fly to Key West from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Key West

How far ahead should I book a flight from Knoxville to Key West?

Use this chart to determine the optimal time to book a round-trip flight from Knoxville to Key West. Price data was last updated on October 31, 2025.

To ensure you get the cheapest price possible for a flight from Knoxville to Key West, you should look to book at least 15 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Knoxville to Key West?

Currently, March is the cheapest month in which you can book a flight from Knoxville to Key West (average of $78). Flying from Knoxville to Key West in December is currently the most expensive (average of $107). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to EYW?

Find hourly flight availability from Knoxville to Key West. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 5, 2025.

A simple way to save on the total cost of your ticket is to fly from Knoxville to Key West in the afternoon. If you’re flexible enough to do this you can expect to save up to 76% on your trip compared to booking a flight in the evening.

Reviews of airlines servicing Key West

Get insights into the airlines that provide service to Key West. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key West. Reviews last updated November 5, 2025.
See what other customers who have flown with Delta, American Airlines, and Allegiant Air from Knoxville to Key West have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,004 reviews

Boarding

8.2

Food

7.3

Comfort

7.9

Entertainment

7.9

Overall

7.9

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Lane,Nov 2025

MEM - ATL

The crew was very friendly, but they only came around and offered the better Delta Comfort snacks one time. I thought they would come around more frequently on a 5 hour flight. They did do two beverage services though, which was nice.
Delta
7.9
Good
8,004 reviews
Delta
7.9
Good
8,004 reviews

Boarding

8.2

Food

7.3

Comfort

7.9

Entertainment

7.9

Overall

7.9

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Lane,Nov 2025

MEM - ATL

The crew was very friendly, but they only came around and offered the better Delta Comfort snacks one time. I thought they would come around more frequently on a 5 hour flight. They did do two beverage services though, which was nice.
American Airlines
7.2
Good
11,039 reviews
Delta
7.9
Good
8,004 reviews

Boarding

8.2

Food

7.3

Comfort

7.9

Entertainment

7.9

Overall

7.9

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Lane,Nov 2025

MEM - ATL

The crew was very friendly, but they only came around and offered the better Delta Comfort snacks one time. I thought they would come around more frequently on a 5 hour flight. They did do two beverage services though, which was nice.
Allegiant Air
7.2
Good
696 reviews
Delta
7.9
Good
8,004 reviews

Boarding

8.2

Food

7.3

Comfort

7.9

Entertainment

7.9

Overall

7.9

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Lane,Nov 2025

MEM - ATL

The crew was very friendly, but they only came around and offered the better Delta Comfort snacks one time. I thought they would come around more frequently on a 5 hour flight. They did do two beverage services though, which was nice.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Key West. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Knoxville to Key West flight route?

    Flights from Knoxville McGhee Tyson to Key West have been viewed 2 times in the past calendar month.

  • How long is the flight from Knoxville to Key West?

    Allegiant Air can get you from Knoxville to Key West in just under 2h 11m. Your travel time will be generally consistent. The distance between Knoxville and Key West is about 788 mi. All flights are typically nonstop.

  • What are the cheapest airlines flying from Knoxville to Key West round-trip?

    According to our current data, Allegiant Air ($80), American Airlines ($248), and Delta ($258) offers the cheapest pricing from Knoxville to Key West. Allegiant Air is currently priced 74% below the average price you’ll pay for this route.

  • What are the cheapest flights from Knoxville to Key West?

    Looking for the cheapest flight from Knoxville to Key West? While on average our users pay $144, our data indicates the cheapest price to be $90. The most popular route (Knoxville McGhee Tyson - Key West), is priced around $84.

  • Can I find deals for flights from Knoxville to Key West that include hotel bookings?

    Yes. In addition to deals on Knoxville to Key West flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Key West?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Key West.

  • Can I find deals for business class flights from Knoxville to Key West?

    Yes. Cheapflights offers flight deals from Knoxville to Key West by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Key West?

    Currently, March is the cheapest month in which you can book a flight from Knoxville to Key West (average of $78). Flying from Knoxville to Key West in December is currently the most expensive (average of $107). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 3 airlines flying from Knoxville to Key West

Discover the top 3 airlines that operate flights from Knoxville to Key West. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 5, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$80Average$145FlexibilityNo cancel feeOn-time88%
American AirlinesCheapest$248Average$437FlexibilityNo cancel feeOn-time71%
DeltaCheapest$258Average$402FlexibilityNo cancel feeOn-timeN/A

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