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Key West

$69+ Cheap flights from Knoxville to Key West (TYS - EYW)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/15. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — EYW
May 29 — Jun 51
Fri 5/29
Fri 6/5
1 adult, Economy
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Find cheap flights from Knoxville to Key West with Cheapflights

1. Tell us where you want to go

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Cheapflights Tip: The best prices from Knoxville McGhee Tyson to Key West are usually found in November or October, booked 19 days in advance, depart on a Tuesday or Monday and return on a Tuesday

Cheap flight deals from Knoxville to Key West

Cheapest flights from Knoxville to Key West
Explore the most affordable flight options available from Knoxville to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 29, 2026.

This Super.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/158:00 am
TYS
-
EYW
Nonstop2h 11m
Allegiant Air
Fri 5/2210:31 am
EYW
-
TYS
Nonstop2h 15m
Allegiant Air
Deal found 4/27$69
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/188:00 am
TYS
-
EYW
Nonstop2h 11m
Allegiant Air
Mon 6/1510:31 am
EYW
-
TYS
Nonstop2h 15m
Allegiant Air
Deal found 4/28$74
This Kiwi.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/177:30 am
TYS
-
EYW
Nonstop2h 11m
Allegiant Air
Mon 7/2010:31 am
EYW
-
TYS
Nonstop2h 15m
Allegiant Air
Deal found 4/25$79
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/48:00 am
TYS
-
EYW
Nonstop2h 11m
Allegiant Air
Fri 5/811:01 am
EYW
-
TYS
Nonstop2h 15m
Allegiant Air
Deal found 4/27$84
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/158:00 am
TYS
-
EYW
Nonstop2h 11m
Allegiant Air
Mon 5/1811:01 am
EYW
-
TYS
Nonstop2h 15m
Allegiant Air
Deal found 4/27$96
This Super.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/18:00 am
TYS
-
EYW
Nonstop2h 11m
Allegiant Air
Mon 5/411:01 am
EYW
-
TYS
Nonstop2h 15m
Allegiant Air
Deal found 4/25$118
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/28:15 am
TYS
-
EYW
Nonstop2h 04m
Allegiant Air
Mon 11/911:54 am
EYW
-
TYS
Nonstop2h 13m
Allegiant Air
Deal found 4/26$127
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/267:30 am
TYS
-
EYW
Nonstop2h 11m
Allegiant Air
Mon 6/2910:31 am
EYW
-
TYS
Nonstop2h 15m
Allegiant Air
Deal found 4/27$131
This Kiwi.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/237:00 am
TYS
-
EYW
Nonstop2h 04m
Allegiant Air
Mon 10/2611:09 am
EYW
-
TYS
Nonstop2h 13m
Allegiant Air
Deal found 4/25$135

Find flight deals from Knoxville to Key West

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Key West (EYW). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$65
(Super.com)

Popular in

August

Cheapest in

November

Average price

$176

Good round-trip deal

$88 or less
Provider with most accurate pricing for Knoxville McGhee Tyson-Key West flight deals.
Search Deals
Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Key West flights.
Search Deals
From Knoxville McGhee Tyson to Key West
Search Deals
Highest demand for flights based on searches. 27% potential increase in price ($88 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($12 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals
Price to beat on a round-trip flight from Knoxville McGhee Tyson to Key West.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2026.
Use the filters below to find and compare flights from Knoxville to Key West that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleKey West

TYS - EYW

TYSEYW

Knoxville McGhee Tyson

Wed 6/24

11:55 am-5:27 pm

1 stop5h 32m

Key West

Mon 6/29

7:50 am-2:49 pm

1 stop6h 59m

$309

KnoxvilleKey West

TYS - EYW

TYSEYW

Knoxville McGhee Tyson

Sat 7/25

8:40 pm-10:24 am

2 stops13h 44m

Key West

Fri 7/31

3:27 pm-9:15 pm

1 stop5h 48m

$309
Quickest round-trip

KnoxvilleKey West

TYS - EYW

TYSEYW

Knoxville McGhee Tyson

Sat 8/29

4:00 pm-7:45 pm

1 stop3h 45m

Key West

Tue 9/1

2:35 pm-6:17 pm

1 stop3h 42m

$323

KnoxvilleKey West

TYS - EYW

TYSEYW

Knoxville McGhee Tyson

Fri 5/15

5:40 am-10:53 am

1 stop5h 13m

Key West

Fri 5/22

7:30 am-1:10 pm

1 stop5h 40m

$334

KnoxvilleKey West

TYS - EYW

TYSEYW

Knoxville McGhee Tyson

Fri 5/15

3:58 pm-10:36 pm

1 stop6h 38m

Key West

Fri 5/22

7:40 pm-11:59 pm

1 stop4h 19m

$384

KnoxvilleKey West

TYS - EYW

TYSEYW

Knoxville McGhee Tyson

Fri 7/24

5:40 am-11:00 am

1 stop5h 20m

Key West

Mon 7/27

7:50 am-2:48 pm

1 stop6h 58m

$396

KnoxvilleKey West

TYS - EYW

TYSEYW

Knoxville McGhee Tyson

Mon 5/18

5:40 am-10:53 am

1 stop5h 13m

Key West

Mon 5/18

6:19 pm-11:56 pm

1 stop5h 37m

$557
Cheapest one-way
Quickest one-way

KnoxvilleKey West

TYS - EYW

TYSEYW

Knoxville McGhee Tyson

Fri 10/23

4:00 pm-7:43 pm

1 stop3h 43m

$279

KnoxvilleKey West

TYS - EYW

TYSEYW

Knoxville McGhee Tyson

Fri 10/23

7:13 am-4:21 pm

2 stops9h 08m

$315

KnoxvilleKey West

TYS - EYW

TYSEYW

Knoxville McGhee Tyson

Fri 10/23

9:45 am-10:11 pm

3 stops36h 26m

$699

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/24

Sorted by cheapest first

Compare providers for flights from Knoxville to Key West

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Key West in April.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
MytripPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Knoxville-Key West flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Key West flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Key West flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Knoxville-Key West flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Key West flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to Key West

Have a flexible travel schedule? Discover the best time to fly to Key West from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Key West

How far ahead should I book a flight from Knoxville to Key West?

To ensure you get the cheapest price possible for a flight from Knoxville to Key West, you should look to book at least 18 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Knoxville to Key West?

Currently, November is the cheapest month in which you can book a flight from Knoxville to Key West (average of $126). Flying from Knoxville to Key West in August is currently the most expensive (average of $363). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to EYW?

Find hourly flight availability from Knoxville to Key West. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 29, 2026.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Knoxville to Key West as you normally would.

How much does it cost to fly round-trip from Knoxville to Key West?

Reviews of airlines servicing Key West

Get insights into the airlines that provide service to Key West. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key West. Reviews last updated April 29, 2026.
See what other customers who have flown with Delta,Allegiant Air, andAmerican Airlines from Knoxville to Key West have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,466 reviews

Crew

8.5

Comfort

7.9

Entertainment

7.8

Overall

7.9

Food

7.2

Boarding

8.1

Reviews

1 / 20
8.0
Excellent

Lane,Nov 2025

MEM - ATL

The crew was very friendly, but they only came around and offered the better Delta Comfort snacks one time. I thought they would come around more frequently on a 5 hour flight. They did do two beverage services though, which was nice.
Delta
7.9
Good
8,466 reviews
Delta
7.9
Good
8,466 reviews

Crew

8.5

Comfort

7.9

Entertainment

7.8

Overall

7.9

Food

7.2

Boarding

8.1

Reviews

1 / 20
8.0
Excellent

Lane,Nov 2025

MEM - ATL

The crew was very friendly, but they only came around and offered the better Delta Comfort snacks one time. I thought they would come around more frequently on a 5 hour flight. They did do two beverage services though, which was nice.
Allegiant Air
7.3
Good
707 reviews
Delta
7.9
Good
8,466 reviews

Crew

8.5

Comfort

7.9

Entertainment

7.8

Overall

7.9

Food

7.2

Boarding

8.1

Reviews

1 / 20
8.0
Excellent

Lane,Nov 2025

MEM - ATL

The crew was very friendly, but they only came around and offered the better Delta Comfort snacks one time. I thought they would come around more frequently on a 5 hour flight. They did do two beverage services though, which was nice.
American Airlines
7.1
Good
11,681 reviews
Delta
7.9
Good
8,466 reviews

Crew

8.5

Comfort

7.9

Entertainment

7.8

Overall

7.9

Food

7.2

Boarding

8.1

Reviews

1 / 20
8.0
Excellent

Lane,Nov 2025

MEM - ATL

The crew was very friendly, but they only came around and offered the better Delta Comfort snacks one time. I thought they would come around more frequently on a 5 hour flight. They did do two beverage services though, which was nice.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Key West. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Knoxville to Key West flight route?

    Flights from Knoxville McGhee Tyson to Key West have been viewed 2 times in the past calendar month.

  • How long is the flight from Knoxville to Key West?

    Delta can get you from Knoxville to Key West in just under 5h 32m. Your travel time can differ by up to . The distance between Knoxville and Key West is about 788 mi.

  • What are the cheapest airlines flying from Knoxville to Key West round-trip?

    According to our current data, Allegiant Air ($84), American Airlines ($250), and Delta ($273) offers the cheapest pricing from Knoxville to Key West. Allegiant Air is currently priced 63% below the average price you’ll pay for this route.

  • What are the cheapest flights from Knoxville to Key West?

    Looking for the cheapest flight from Knoxville to Key West? While on average our users pay $136, our data indicates the cheapest price to be $66. The most popular route (Knoxville McGhee Tyson - Key West), is priced around $69.

  • Can I find deals for flights from Knoxville to Key West that include hotel bookings?

    Yes. In addition to deals on Knoxville to Key West flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Key West?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Key West.

  • Can I find deals for business class flights from Knoxville to Key West?

    Yes. Cheapflights offers flight deals from Knoxville to Key West by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Key West?

    Currently, November is the cheapest month in which you can book a flight from Knoxville to Key West (average of $126). Flying from Knoxville to Key West in August is currently the most expensive (average of $363). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 3 airlines flying from Knoxville to Key West

Discover the top 3 airlines that operate flights from Knoxville to Key West. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$84Average$147FlexibilityNo cancel feeOn-time88%
American AirlinesCheapest$250Average$391FlexibilityNo cancel feeOn-time71%
DeltaCheapest$273Average$408FlexibilityNo cancel feeOn-timeN/A

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