$135+ Cheap flights from Knoxville to Fort Myers (TYS - RSW)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/9. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — RSW
Sep 20 — Sep 271
Round-trip
1 adult, Economy
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Find cheap flights from Knoxville to Fort Myers with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Knoxville to Fort Myers
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Cheapest flights from Knoxville to Fort MyersExplore the most affordable flight options available from Knoxville to Fort Myers. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 21, 2026.
Explore the most affordable flight options available from Knoxville to Fort Myers. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 21, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1010:54 am -
2 stops24h 57m
Mon 9/1412:46 pm -
1 stop6h 48m
Deal found 8/21![Multiple Airlines logo]()
$254
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/85:19 pm -
1 stop4h 32m
Wed 12/164:47 pm -
1 stop3h 56m
Deal found 8/18![American Airlines logo]()
$259
This Southwest deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/211:00 pm -
1 stop9h 00m
Wed 10/288:15 am -
1 stop4h 05m
Deal found 8/18![Southwest logo]()
$264
This Delta deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/155:40 am -
1 stop4h 10m
Mon 10/197:56 pm -
1 stop4h 02m
Deal found 8/18![Delta logo]()
$277
This American Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/307:58 pm -
1 stop4h 01m
Mon 11/26:24 pm -
1 stop4h 24m
Deal found 8/21![American Airlines logo]()
$284
This Southwest deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/201:00 pm -
1 stop9h 00m
Sat 10/247:05 am -
2 stops9h 40m
Deal found 8/18![Southwest logo]()
$287
This Delta deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:23 pm -
1 stop4h 47m
Sun 10/187:56 pm -
1 stop4h 03m
Deal found 8/18![Delta logo]()
$310
This Delta deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/105:40 am -
1 stop4h 12m
Mon 9/146:19 pm -
1 stop5h 36m
Deal found 8/21![Delta logo]()
$314
This Southwest deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/228:05 am -
2 stops11h 50m
Mon 10/56:25 pm -
1 stop4h 15m
Deal found 8/18![Southwest logo]()
$318
This American Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/46:07 pm -
1 stop4h 55m
Sun 12/67:28 pm -
1 stop4h 30m
Deal found 8/21![American Airlines logo]()
$326
Best flights from Knoxville to Fort MyersDiscover carefully curated flight deals from Knoxville to Fort Myers that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 21, 2026.
Discover carefully curated flight deals from Knoxville to Fort Myers that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 21, 2026.
This Delta deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:23 pm -
1 stop4h 47m
Sun 10/187:56 pm -
1 stop4h 03m
Deal found 8/18![Delta logo]()
$310
This Southwest deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2212:45 pm -
1 stop7h 10m
Wed 9/2312:20 pm -
1 stop7h 35m
Deal found 8/20![Southwest logo]()
$318
This Delta deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/142:38 pm -
1 stop4h 12m
Sun 10/187:00 am -
1 stop3h 49m
Deal found 8/18![Delta logo]()
$310
This Delta deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/266:23 pm -
1 stop4h 47m
Sun 11/15:30 am -
1 stop5h 15m
Deal found 8/20![Delta logo]()
$310
This Southwest deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/148:20 am -
2 stops13h 40m
Mon 10/192:25 pm -
2 stops8h 15m
Deal found 8/18![Southwest logo]()
$373
This Southwest deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/28:20 am -
1 stop7h 50m
Tue 10/67:20 am -
1 stop9h 20m
Deal found 8/17![Southwest logo]()
$433
This Southwest deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/108:25 am -
2 stops13h 40m
Mon 9/147:20 am -
2 stops11h 20m
Deal found 8/21![Southwest logo]()
$435
This Delta deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/310:28 am -
1 stop6h 16m
Mon 9/75:35 am -
1 stop5h 36m
Deal found 8/20![Delta logo]()
$467
This Southwest deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/41:00 pm -
1 stop9h 05m
Tue 9/87:20 am -
1 stop5h 45m
Deal found 8/16![Southwest logo]()
$452
This Southwest deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/2612:50 pm -
2 stops9h 15m
Sun 11/19:20 am -
2 stops11h 10m
Deal found 8/20![Southwest logo]()
$453
Last-minute flights from Knoxville to Fort MyersDiscover last-minute flight deals from Knoxville to Fort Myers. Data last updated August 21, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to Fort Myers. Data last updated August 21, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1010:54 am -
2 stops24h 57m
Mon 9/1412:46 pm -
1 stop6h 48m
Deal found 8/21![Multiple Airlines logo]()
$254
This Delta deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/105:40 am -
1 stop4h 12m
Mon 9/146:19 pm -
1 stop5h 36m
Deal found 8/21![Delta logo]()
$314
This Delta deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/147:25 pm -
1 stop5h 10m
Mon 9/213:35 pm -
1 stop4h 40m
Deal found 8/17![Delta logo]()
$277
This Kiwi.com deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/144:18 pm -
2 stops40h 28m
Mon 9/2110:06 am -
1 stop9h 28m
Deal found 8/17![Multiple Airlines logo]()
$342
This Southwest deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1612:45 pm -
1 stop7h 10m
Wed 9/238:45 am -
2 stops11h 10m
Deal found 8/19![Southwest logo]()
$329
This Delta deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/215:40 am -
1 stop4h 12m
Wed 9/3010:57 am -
1 stop6h 31m
Deal found 8/18![Delta logo]()
$338
This Southwest deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/211:00 pm -
1 stop9h 05m
Tue 9/227:20 am -
1 stop5h 45m
Deal found 8/16![Southwest logo]()
$364
This Southwest deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected ” under the list of providers to see comparable flight deals.
Mon 9/211:00 pm -
1 stop9h 05m
Wed 9/308:45 am -
2 stops11h 10m
Deal found 8/18![Southwest logo]()
$369
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/226:15 am -
1 stop4h 09m
Mon 10/57:51 pm -
1 stop4h 04m
Deal found 8/18![American Airlines logo]()
$259
This Southwest deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/228:05 am -
2 stops11h 50m
Mon 10/56:25 pm -
1 stop4h 15m
Deal found 8/18![Southwest logo]()
$318
This Southwest deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/228:05 am -
2 stops11h 50m
Wed 9/238:45 am -
2 stops11h 10m
Deal found 8/20![Southwest logo]()
$383
One-way flights from Knoxville to Fort MyersSearch for one-way flight options from Knoxville to Fort Myers. Find affordable one-way fares based on user searches. Data last updated August 21, 2026.
Search for one-way flight options from Knoxville to Fort Myers. Find affordable one-way fares based on user searches. Data last updated August 21, 2026.
This Southwest deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/97:00 am -
2 stops10h 00m
Deal found 8/16![Southwest logo]()
$135
This Delta deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/195:45 pm -
1 stop3h 49m
Deal found 8/21![Delta logo]()
$139
This Delta deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/257:45 pm -
1 stop4h 36m
Deal found 8/17![Delta logo]()
$172
This Kiwi.com deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/46:11 pm -
2 stops29h 00m
Deal found 8/19![Multiple Airlines logo]()
$186
This Southwest deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/197:50 am -
2 stops11h 05m
Deal found 8/21![Southwest logo]()
$209
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/75:15 am -
1 stop4h 59m
Deal found 8/18![American Airlines logo]()
$224
This Kiwi.com deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/196:55 pm -
3 stops25h 21m
Deal found 8/21![Multiple Airlines logo]()
$233
This Kiwi.com deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/72:30 pm -
2 stops42h 16m
Deal found 8/18![Multiple Airlines logo]()
$248
This Kiwi.com deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/910:54 am -
3 stops34h 53m
Deal found 8/16![Multiple Airlines logo]()
$249
This Delta deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2910:28 am -
1 stop5h 11m
Deal found 8/20![Delta logo]()
$299
Find flight deals from Knoxville to Fort Myers
Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Fort Myers (RSW). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 21, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $254 (Kiwi.com) |
One-way from | $135 (Southwest) |
Popular in | March |
Cheapest in | February |
Average price | $278 |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to Fort Myers that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 21, 2026.
Use the filters below to find and compare flights from Knoxville to Fort Myers that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvilleFort Myers
TYS Knoxville McGhee Tyson - RSW Fort Myers SW Florida Intl
TYSRSW
Knoxville McGhee Tyson
Thu 10/15
6:23 pm-11:10 pm
1 stop4h 47m
Fort Myers SW Florida Intl
Sun 10/18
7:56 pm-11:59 pm
1 stop4h 03m
$310
Quickest round-trip
KnoxvilleFort Myers
TYS Knoxville McGhee Tyson - RSW Fort Myers SW Florida Intl
TYSRSW
Knoxville McGhee Tyson
Wed 10/14
2:38 pm-6:50 pm
1 stop4h 12m
Fort Myers SW Florida Intl
Sun 10/18
7:00 am-10:49 am
1 stop3h 49m
$310
KnoxvilleFort Myers
TYS Knoxville McGhee Tyson - RSW Fort Myers SW Florida Intl
TYSRSW
Knoxville McGhee Tyson
Mon 10/26
6:23 pm-11:10 pm
1 stop4h 47m
Fort Myers SW Florida Intl
Sun 11/1
5:30 am-10:45 am
1 stop5h 15m
$310
KnoxvilleFort Myers
TYS Knoxville McGhee Tyson - RSW Fort Myers SW Florida Intl
TYSRSW
Knoxville McGhee Tyson
Tue 9/22
12:45 pm-7:55 pm
1 stop7h 10m
Fort Myers SW Florida Intl
Wed 9/23
12:20 pm-7:55 pm
1 stop7h 35m
$318
KnoxvilleFort Myers
TYS Knoxville McGhee Tyson - RSW Fort Myers SW Florida Intl
TYSRSW
Knoxville McGhee Tyson
Wed 10/14
8:20 am-10:00 pm
2 stops13h 40m
Fort Myers SW Florida Intl
Mon 10/19
2:25 pm-10:40 pm
2 stops8h 15m
$373
KnoxvilleFort Myers
TYS Knoxville McGhee Tyson - RSW Fort Myers SW Florida Intl
TYSRSW
Knoxville McGhee Tyson
Fri 10/2
8:20 am-4:10 pm
1 stop7h 50m
Fort Myers SW Florida Intl
Tue 10/6
7:20 am-4:40 pm
1 stop9h 20m
$433
KnoxvilleFort Myers
TYS Knoxville McGhee Tyson - RSW Fort Myers SW Florida Intl
TYSRSW
Knoxville McGhee Tyson
Thu 9/10
8:25 am-10:05 pm
2 stops13h 40m
Fort Myers SW Florida Intl
Mon 9/14
7:20 am-6:40 pm
2 stops11h 20m
$435
KnoxvilleFort Myers
TYS Knoxville McGhee Tyson - RSW Fort Myers SW Florida Intl
TYSRSW
Knoxville McGhee Tyson
Fri 9/4
1:00 pm-10:05 pm
1 stop9h 05m
Fort Myers SW Florida Intl
Tue 9/8
7:20 am-1:05 pm
1 stop5h 45m
$452
KnoxvilleFort Myers
TYS Knoxville McGhee Tyson - RSW Fort Myers SW Florida Intl
TYSRSW
Knoxville McGhee Tyson
Mon 10/26
12:50 pm-10:05 pm
2 stops9h 15m
Fort Myers SW Florida Intl
Sun 11/1
9:20 am-8:30 pm
2 stops11h 10m
$453
KnoxvilleFort Myers
TYS Knoxville McGhee Tyson - RSW Fort Myers SW Florida Intl
TYSRSW
Knoxville McGhee Tyson
Thu 9/3
10:28 am-4:44 pm
1 stop6h 16m
Fort Myers SW Florida Intl
Mon 9/7
5:35 am-11:11 am
1 stop5h 36m
$467
Showing 1-10 of 20 resultsSorted by cheapest first
Compare providers for flights from Knoxville to Fort Myers
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Fort Myers in August.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Knoxville-Fort Myers flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Fort Myers flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Fort Myers flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Knoxville-Fort Myers flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Fort Myers flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Knoxville to Fort Myers
Have a flexible travel schedule? Discover the best time to fly to Fort Myers from Knoxville with our price prediction graph.
TYS-RSW
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Knoxville to Fort Myers
What is the cheapest month to book a flight from Knoxville to Fort Myers?
Currently, February is the cheapest month in which you can book a flight from Knoxville to Fort Myers (average of $236). Flying from Knoxville to Fort Myers in March is currently the most expensive (average of $552). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Knoxville to Fort Myers?
Airfare is below average for this route at the moment.
Knoxville to Fort Myers flights typically cost between $361 and $486 in September.The cheapest round-trip price found within the last 5 days was $254 on Multiple Airlines (Sep 10-Sep 14).
Reviews of airlines servicing Fort Myers
Get insights into the airlines that provide service to Fort Myers. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Fort Myers. Reviews last updated August 21, 2026.
Peruse reviews from past customers who have flown with Delta and American Airlines from Knoxville to Fort Myers to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.8
Entertainment
7.8
Boarding
8.1
Crew
8.5
Food
7.2
Comfort
7.8
Reviews
1 / 20
4.0
OkayJoel,May 2026
ATL - JAX
Overall
7.8
Entertainment
7.8
Boarding
8.1
Crew
8.5
Food
7.2
Comfort
7.8
Reviews
1 / 20
4.0
OkayJoel,May 2026
ATL - JAX
Overall
7.8
Entertainment
7.8
Boarding
8.1
Crew
8.5
Food
7.2
Comfort
7.8
Reviews
1 / 20
4.0
OkayJoel,May 2026
ATL - JAX
Related info for your journey
Find useful and relevant information for your journey from Knoxville to Fort Myers. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Fort Myers?
Book flights to Fort Myers if you plan to visit one of these locationsNorth Fort Myers
Lehigh Acres
Sanibel
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Knoxville and Fort Myers flights
Browse other Knoxville and Fort Myers flight options. Last updated on August 21, 2026.
Other flights from Knoxville
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Top 2 airlines flying from Knoxville to Fort Myers
Discover the top 2 airlines that operate flights from Knoxville to Fort Myers. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 21, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$258 | Average$408 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$267 | Average$474 | FlexibilityNo cancel fee | On-timeN/A |