$153+ Cheap flights from Fort Myers to Knoxville (RSW - TYS)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/20. Fares are subject to change and may not be available on all flights or dates of travel.
RSW — TYS
Jul 8 — Jul 151
Round-trip
1 adult, Economy
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1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Fort Myers to Knoxville
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Cheapest flights from Fort Myers to KnoxvilleExplore the most affordable flight options available from Fort Myers to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 8, 2026.
Explore the most affordable flight options available from Fort Myers to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 8, 2026.
This SmartFares deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/46:50 am
RSW
- TYS
1 stop4h 16m
Delta
Tue 11/172:30 pm
TYS
- RSW
1 stop4h 23m
Delta
Deal found 6/3![Delta logo]()
$272
This American Airlines deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/216:22 am
RSW
- TYS
1 stop6h 12m
American Airlines
Thu 7/2310:00 am
TYS
- RSW
1 stop5h 09m
American Airlines
Deal found 6/3![American Airlines logo]()
$302
This Delta deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/46:30 pm
RSW
- TYS
1 stop5h 16m
Delta
Tue 11/1010:05 am
TYS
- RSW
1 stop3h 48m
Delta
Deal found 6/5![Delta logo]()
$311
This Southwest deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/216:10 am
RSW
- TYS
2 stops5h 55m
Southwest
Thu 7/2312:35 pm
TYS
- RSW
2 stops9h 20m
Southwest
Deal found 6/3![Southwest logo]()
$312
This Southwest deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/46:55 am
RSW
- TYS
1 stop11h 20m
Southwest
Fri 7/1012:35 pm
TYS
- RSW
1 stop9h 25m
Southwest
Deal found 6/4![Southwest logo]()
$313
This Delta deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/36:40 am
RSW
- TYS
1 stop4h 31m
Delta
Tue 9/85:30 am
TYS
- RSW
1 stop6h 27m
Delta
Deal found 6/3![Delta logo]()
$316
This Delta deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/16:40 am
RSW
- TYS
1 stop4h 31m
Delta
Sun 9/66:00 am
TYS
- RSW
1 stop3h 55m
Delta
Deal found 6/4![Delta logo]()
$317
This American Airlines deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/17:20 am
RSW
- TYS
1 stop6h 11m
American Airlines
Sun 9/67:00 am
TYS
- RSW
1 stop6h 10m
American Airlines
Deal found 6/6![American Airlines logo]()
$318
This American Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/237:41 pm
RSW
- TYS
1 stop4h 10m
American Airlines
Thu 7/301:00 pm
TYS
- RSW
1 stop5h 51m
American Airlines
Deal found 6/7![American Airlines logo]()
$319
This Southwest deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/36:15 am
RSW
- TYS
1 stop7h 30m
Southwest
Mon 8/1012:40 pm
TYS
- RSW
1 stop9h 20m
Southwest
Deal found 6/5![Southwest logo]()
$323
Best flights from Fort Myers to KnoxvilleDiscover carefully curated flight deals from Fort Myers to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 8, 2026.
Discover carefully curated flight deals from Fort Myers to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 8, 2026.
This Southwest deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2111:25 am
RSW
- TYS
2 stops9h 55m
Southwest
Thu 7/2312:35 pm
TYS
- RSW
1 stop9h 25m
Southwest
Deal found 6/3![Southwest logo]()
$313
This Delta deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/18:04 am
RSW
- TYS
1 stop5h 30m
Delta
Sun 9/66:00 am
TYS
- RSW
1 stop6h 13m
Delta
Deal found 6/5![Delta logo]()
$320
This Delta deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/256:27 pm
RSW
- TYS
1 stop5h 17m
Delta
Mon 7/276:05 pm
TYS
- RSW
1 stop6h 18m
Delta
Deal found 6/3![Delta logo]()
$331
This Delta deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/195:35 am
RSW
- TYS
1 stop4h 01m
Delta
Sun 7/265:40 am
TYS
- RSW
1 stop4h 03m
Delta
Deal found 6/7![Delta logo]()
$355
This Southwest deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/128:15 am
RSW
- TYS
1 stop3h 55m
Southwest
Sun 11/157:05 am
TYS
- RSW
2 stops11h 05m
Southwest
Deal found 6/6![Southwest logo]()
$402
This Delta deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/265:37 am
RSW
- TYS
1 stop4h 01m
Delta
Tue 6/307:35 am
TYS
- RSW
1 stop4h 39m
Delta
Deal found 6/5![Delta logo]()
$367
This Southwest deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1910:30 am
RSW
- TYS
2 stops9h 20m
Southwest
Mon 11/2312:50 pm
TYS
- RSW
2 stops8h 50m
Southwest
Deal found 6/7![Southwest logo]()
$417
This Southwest deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/256:20 am
RSW
- TYS
2 stops5h 35m
Southwest
Mon 7/277:30 am
TYS
- RSW
1 stop10h 50m
Southwest
Deal found 6/3![Southwest logo]()
$424
Last-minute flights from Fort Myers to KnoxvilleDiscover last-minute flight deals from Fort Myers to Knoxville. Data last updated June 8, 2026 and is based on user searches.
Discover last-minute flight deals from Fort Myers to Knoxville. Data last updated June 8, 2026 and is based on user searches.
This Southwest deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/46:55 am
RSW
- TYS
1 stop11h 20m
Southwest
Fri 7/1012:35 pm
TYS
- RSW
1 stop9h 25m
Southwest
Deal found 6/4![Southwest logo]()
$313
This Delta deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/85:35 am
RSW
- TYS
1 stop5h 35m
Delta
Wed 7/87:43 pm
TYS
- RSW
1 stop4h 40m
Delta
Deal found 6/5![Delta logo]()
$340
This Southwest deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/92:05 pm
RSW
- TYS
1 stop8h 30m
Southwest
Wed 7/157:10 am
TYS
- RSW
1 stop9h 30m
Southwest
Deal found 6/5![Southwest logo]()
$332
This Southwest deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/144:40 pm
RSW
- TYS
1 stop3h 45m
Southwest
Sun 7/197:00 pm
TYS
- RSW
1 stop4h 00m
Southwest
Deal found 6/5![Southwest logo]()
$361
This Delta deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/195:35 am
RSW
- TYS
1 stop4h 01m
Delta
Sun 7/265:40 am
TYS
- RSW
1 stop4h 03m
Delta
Deal found 6/7![Delta logo]()
$355
This American Airlines deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/216:22 am
RSW
- TYS
1 stop6h 12m
American Airlines
Thu 7/2310:00 am
TYS
- RSW
1 stop5h 09m
American Airlines
Deal found 6/3![American Airlines logo]()
$302
This Southwest deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/216:10 am
RSW
- TYS
2 stops5h 55m
Southwest
Thu 7/2312:35 pm
TYS
- RSW
2 stops9h 20m
Southwest
Deal found 6/3![Southwest logo]()
$312
This American Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/237:41 pm
RSW
- TYS
1 stop4h 10m
American Airlines
Thu 7/301:00 pm
TYS
- RSW
1 stop5h 51m
American Airlines
Deal found 6/7![American Airlines logo]()
$319
This Delta deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/235:35 am
RSW
- TYS
1 stop5h 35m
Delta
Thu 7/307:49 pm
TYS
- RSW
1 stop4h 34m
Delta
Deal found 6/5![Delta logo]()
$341
This Delta deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/256:27 pm
RSW
- TYS
1 stop5h 17m
Delta
Mon 7/276:05 pm
TYS
- RSW
1 stop6h 18m
Delta
Deal found 6/3![Delta logo]()
$331
One-way flights from Fort Myers to KnoxvilleSearch for one-way flight options from Fort Myers to Knoxville. Find affordable one-way fares based on user searches. Data last updated June 8, 2026.
Search for one-way flight options from Fort Myers to Knoxville. Find affordable one-way fares based on user searches. Data last updated June 8, 2026.
This American Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/206:34 pm
RSW
- TYS
1 stop4h 24m
American Airlines
Deal found 6/4![American Airlines logo]()
$153
This Southwest deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/157:20 am
RSW
- TYS
1 stop7h 20m
Southwest
Deal found 6/5![Southwest logo]()
$158
This Southwest deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/307:40 am
RSW
- TYS
1 stop4h 45m
Southwest
Deal found 6/7![Southwest logo]()
$160
This Delta deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/206:29 pm
RSW
- TYS
1 stop5h 23m
Delta
Deal found 6/6![Delta logo]()
$161
This Southwest deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/216:10 am
RSW
- TYS
1 stop10h 50m
Southwest
Deal found 6/6![Southwest logo]()
$165
This Southwest deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/32:05 pm
RSW
- TYS
1 stop8h 25m
Southwest
Deal found 6/6![Southwest logo]()
$175
This Kiwi.com deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/128:10 am
RSW
- TYS
2 stops30h 06m
Multiple Airlines
Deal found 6/7![Multiple Airlines logo]()
$193
This American Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/286:16 am
RSW
- TYS
1 stop4h 20m
American Airlines
Deal found 6/4![American Airlines logo]()
$199
This Delta deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/286:45 am
RSW
- TYS
1 stop6h 34m
Delta
Deal found 6/7![Delta logo]()
$207
Find flight deals from Fort Myers to Knoxville
Discover tips and strategies to find the most affordable flight options for your journey from Fort Myers (RSW) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 8, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $271 (SmartFares) |
One-way from | $153 (American Airlines) |
Popular in | January |
Cheapest in | September |
Average price | $413 |
Cheapflights Fare Finder
Customize your flight search to find flights from Fort Myers to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 8, 2026.
Use the filters below to find and compare flights from Fort Myers to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Fort MyersKnoxville
RSW - TYS
RSWTYS
Fort Myers SW Florida Intl
Tue 7/21
11:25 am-9:20 pm
2 stops9h 55m
Knoxville McGhee Tyson
Thu 7/23
12:35 pm-10:00 pm
1 stop9h 25m
$313
Fort MyersKnoxville
RSW - TYS
RSWTYS
Fort Myers SW Florida Intl
Tue 9/1
8:04 am-1:34 pm
1 stop5h 30m
Knoxville McGhee Tyson
Sun 9/6
6:00 am-12:13 pm
1 stop6h 13m
$320
Fort MyersKnoxville
RSW - TYS
RSWTYS
Fort Myers SW Florida Intl
Sat 7/25
6:27 pm-11:44 pm
1 stop5h 17m
Knoxville McGhee Tyson
Mon 7/27
6:05 pm-12:23 am
1 stop6h 18m
$331
Quickest round-trip
Fort MyersKnoxville
RSW - TYS
RSWTYS
Fort Myers SW Florida Intl
Sun 7/19
5:35 am-9:36 am
1 stop4h 01m
Knoxville McGhee Tyson
Sun 7/26
5:40 am-9:43 am
1 stop4h 03m
$355
Fort MyersKnoxville
RSW - TYS
RSWTYS
Fort Myers SW Florida Intl
Fri 6/26
5:37 am-9:38 am
1 stop4h 01m
Knoxville McGhee Tyson
Tue 6/30
7:35 am-12:14 pm
1 stop4h 39m
$367
Fort MyersKnoxville
RSW - TYS
RSWTYS
Fort Myers SW Florida Intl
Thu 11/12
8:15 am-12:10 pm
1 stop3h 55m
Knoxville McGhee Tyson
Sun 11/15
7:05 am-6:10 pm
2 stops11h 05m
$402
Fort MyersKnoxville
RSW - TYS
RSWTYS
Fort Myers SW Florida Intl
Thu 11/19
10:30 am-7:50 pm
2 stops9h 20m
Knoxville McGhee Tyson
Mon 11/23
12:50 pm-9:40 pm
2 stops8h 50m
$417
Fort MyersKnoxville
RSW - TYS
RSWTYS
Fort Myers SW Florida Intl
Sat 7/25
6:20 am-11:55 am
2 stops5h 35m
Knoxville McGhee Tyson
Mon 7/27
7:30 am-6:20 pm
1 stop10h 50m
$424
Cheapest one-way
Fort MyersKnoxville
RSW - TYS
RSWTYS
Fort Myers SW Florida Intl
Thu 8/20
6:34 pm-10:58 pm
1 stop4h 24m
$153
Fort MyersKnoxville
RSW - TYS
RSWTYS
Fort Myers SW Florida Intl
Thu 8/20
6:29 pm-11:52 pm
1 stop5h 23m
$161
Showing 1-10 of 17 resultsSorted by cheapest first
Compare providers for flights from Fort Myers to Knoxville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Fort Myers to Knoxville in June.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Fort Myers-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Fort Myers-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Fort Myers-Knoxville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Fort Myers-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Fort Myers-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Fort Myers to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from Fort Myers with our price prediction graph.
RSW-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Fort Myers to Knoxville
What is the cheapest month to book a flight from Fort Myers to Knoxville?
Currently, September is the cheapest month in which you can book a flight from Fort Myers to Knoxville (average of $319). Flying from Fort Myers to Knoxville in January is currently the most expensive (average of $715). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Fort Myers to Knoxville?
Reviews of airlines servicing Knoxville
Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated June 8, 2026.
See what other customers who have flown with Delta and American Airlines from Fort Myers to Knoxville have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.9
Boarding
8.1
Comfort
7.8
Entertainment
7.8
Crew
8.5
Food
7.2
Reviews
1 / 20
6.0
Goodpilar,May 2025
RSW - ATL
Overall
7.9
Boarding
8.1
Comfort
7.8
Entertainment
7.8
Crew
8.5
Food
7.2
Reviews
1 / 20
6.0
Goodpilar,May 2025
RSW - ATL
Overall
7.9
Boarding
8.1
Comfort
7.8
Entertainment
7.8
Crew
8.5
Food
7.2
Reviews
1 / 20
6.0
Goodpilar,May 2025
RSW - ATL
Related info for your journey
Find useful and relevant information for your journey from Fort Myers to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsCherokee
Crossville
Morristown
Bryson City
Murphy
Alcoa
Oak Ridge
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Top 2 airlines flying from Fort Myers to Knoxville
Discover the top 2 airlines that operate flights from Fort Myers to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 8, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$248 | Average$445 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$248 | Average$370 | FlexibilityNo cancel fee | On-timeN/A |