$130+ Cheap flights from Fort Myers to Knoxville (RSW - TYS)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/16. Fares are subject to change and may not be available on all flights or dates of travel.
RSW — TYS
Nov 18 — Nov 251
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Fort Myers to Knoxville
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Cheapest flights from Fort Myers to KnoxvilleExplore the most affordable flight options available from Fort Myers to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 19, 2026.
Explore the most affordable flight options available from Fort Myers to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 19, 2026.
This Delta deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/77:00 am -
1 stop6h 31m
Tue 11/106:10 pm -
1 stop6h 30m
Deal found 10/14![Delta logo]()
$275
This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1811:08 am -
1 stop5h 40m
Mon 11/238:50 am -
1 stop4h 45m
Deal found 10/15![American Airlines logo]()
$289
This American Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/37:19 pm -
1 stop4h 40m
Sun 12/66:02 pm -
1 stop5h 02m
Deal found 10/16![American Airlines logo]()
$312
This Southwest deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/87:25 am -
1 stop9h 25m
Sat 11/142:50 pm -
1 stop4h 05m
Deal found 10/15![Southwest logo]()
$317
This American Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/137:28 pm -
1 stop4h 30m
Fri 11/205:01 pm -
1 stop6h 16m
Deal found 10/16![American Airlines logo]()
$324
This American Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/102:32 pm -
1 stop4h 58m
Sun 12/136:02 pm -
1 stop5h 02m
Deal found 10/17![American Airlines logo]()
$349
This Delta deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/62:52 pm -
1 stop4h 50m
Mon 11/97:22 pm -
1 stop3h 59m
Deal found 10/16![Delta logo]()
$357
This Delta deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/107:58 pm -
1 stop3h 59m
Sun 12/137:26 pm -
1 stop4h 02m
Deal found 10/19![Delta logo]()
$363
This American Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/237:29 pm -
1 stop4h 30m
Fri 11/276:50 am -
1 stop6h 44m
Deal found 10/14![American Airlines logo]()
$369
This American Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/167:49 am -
1 stop5h 56m
Fri 12/186:07 pm -
1 stop6h 31m
Deal found 10/18![American Airlines logo]()
$384
This Southwest deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/187:30 am -
1 stop4h 50m
Mon 11/2312:50 pm -
2 stops8h 55m
Deal found 10/15![Southwest logo]()
$392
Best flights from Fort Myers to KnoxvilleDiscover carefully curated flight deals from Fort Myers to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 19, 2026.
Discover carefully curated flight deals from Fort Myers to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 19, 2026.
This Southwest deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/31:35 pm -
1 stop7h 15m
Sun 12/67:05 am -
1 stop8h 50m
Deal found 10/16![Southwest logo]()
$317
This Delta deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/133:35 pm -
1 stop3h 57m
Sun 11/157:22 pm -
1 stop5h 18m
Deal found 10/16![Delta logo]()
$328
This Delta deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/107:58 pm -
1 stop3h 59m
Sun 12/137:26 pm -
1 stop4h 02m
Deal found 10/19![Delta logo]()
$363
This Southwest deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/138:00 am -
2 stops9h 10m
Sun 1/177:00 am -
2 stops13h 35m
Deal found 10/17![Southwest logo]()
$428
This Southwest deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/57:25 am -
1 stop9h 25m
Mon 11/912:50 pm -
2 stops9h 05m
Deal found 10/19![Southwest logo]()
$468
This Southwest deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3012:30 pm -
2 stops10h 15m
Mon 11/28:10 am -
2 stops11h 15m
Deal found 10/14![Southwest logo]()
$503
This Delta deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/57:00 am -
1 stop6h 31m
Sun 11/86:23 pm -
1 stop4h 47m
Deal found 10/16![Delta logo]()
$619
This Southwest deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/2311:10 am -
2 stops10h 30m
Wed 12/3012:40 pm -
2 stops7h 05m
Deal found 10/14![Southwest logo]()
$527
This Southwest deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/238:15 am -
2 stops8h 35m
Fri 11/277:05 am -
2 stops11h 05m
Deal found 10/14![Southwest logo]()
$561
This Southwest deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/227:15 am -
1 stop5h 55m
Thu 11/512:50 pm -
1 stop9h 15m
Deal found 10/18![Southwest logo]()
$618
This Southwest deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/247:30 am -
2 stops9h 10m
Sun 12/277:15 pm -
1 stop5h 25m
Deal found 10/17![Southwest logo]()
$637
This Southwest deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/256:15 am -
1 stop5h 55m
Tue 10/277:15 am -
1 stop6h 05m
Deal found 10/16![Southwest logo]()
$639
Last-minute flights from Fort Myers to KnoxvilleDiscover last-minute flight deals from Fort Myers to Knoxville. Data last updated October 19, 2026 and is based on user searches.
Discover last-minute flight deals from Fort Myers to Knoxville. Data last updated October 19, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/62:52 pm -
1 stop4h 50m
Mon 11/97:22 pm -
1 stop3h 59m
Deal found 10/16![Delta logo]()
$357
This Delta deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/77:00 am -
1 stop6h 31m
Tue 11/106:10 pm -
1 stop6h 30m
Deal found 10/14![Delta logo]()
$275
This Southwest deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/87:25 am -
1 stop9h 25m
Sat 11/142:50 pm -
1 stop4h 05m
Deal found 10/15![Southwest logo]()
$317
This American Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/122:32 pm -
1 stop7h 09m
Sun 11/158:49 am -
1 stop5h 46m
Deal found 10/16![American Airlines logo]()
$427
This American Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/137:28 pm -
1 stop4h 30m
Fri 11/205:01 pm -
1 stop6h 16m
Deal found 10/16![American Airlines logo]()
$324
This Southwest deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/138:15 am -
1 stop3h 55m
Fri 11/2011:45 am -
2 stops10h 10m
Deal found 10/16![Southwest logo]()
$398
This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1811:08 am -
1 stop5h 40m
Mon 11/238:50 am -
1 stop4h 45m
Deal found 10/15![American Airlines logo]()
$289
This Southwest deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/187:30 am -
1 stop4h 50m
Mon 11/2312:50 pm -
2 stops8h 55m
Deal found 10/15![Southwest logo]()
$392
This American Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/237:29 pm -
1 stop4h 30m
Fri 11/276:50 am -
1 stop6h 44m
Deal found 10/14![American Airlines logo]()
$369
One-way flights from Fort Myers to KnoxvilleSearch for one-way flight options from Fort Myers to Knoxville. Find affordable one-way fares based on user searches. Data last updated October 19, 2026.
Search for one-way flight options from Fort Myers to Knoxville. Find affordable one-way fares based on user searches. Data last updated October 19, 2026.
This American Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/166:24 pm -
1 stop4h 24m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/14![American Airlines logo]()
$130
This Delta deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/67:00 am -
1 stop3h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/14![Delta logo]()
$138
This Delta deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/167:59 pm -
1 stop4h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![Delta logo]()
$144
This Delta deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/267:00 am -
1 stop6h 26m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/16![Delta logo]()
$159
This Southwest deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/133:00 pm -
1 stop6h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/18![Southwest logo]()
$176
This Kiwi.com deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/65:15 pm -
3 stops42h 08m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/14![Multiple Airlines logo]()
$193
This Kiwi.com deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/266:00 am -
2 stops35h 14m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/17![Multiple Airlines logo]()
$204
This Delta deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/205:30 am -
1 stop4h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/18![Delta logo]()
$210
Find flight deals from Fort Myers to Knoxville
Discover tips and strategies to find the most affordable flight options for your journey from Fort Myers (RSW) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 19, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $229 (American Airlines) |
One-way from | $130 (American Airlines) |
Popular in | January |
Cheapest in | August |
Average price | $411 |
Cheapflights Fare Finder
Customize your flight search to find flights from Fort Myers to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 19, 2026.
Use the filters below to find and compare flights from Fort Myers to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Fort MyersKnoxville
RSW Fort Myers SW Florida Intl - TYS Knoxville McGhee Tyson
RSWTYS
Fort Myers SW Florida Intl
Mon 11/16
6:24 pm-10:48 pm
1 stop4h 24m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$130
Quickest round-trip
Fort MyersKnoxville
RSW Fort Myers SW Florida Intl - TYS Knoxville McGhee Tyson
RSWTYS
Fort Myers SW Florida Intl
Fri 11/6
7:00 am-10:45 am
1 stop3h 45m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$138
Fort MyersKnoxville
RSW Fort Myers SW Florida Intl - TYS Knoxville McGhee Tyson
RSWTYS
Fort Myers SW Florida Intl
Mon 11/16
7:59 pm-11:59 pm
1 stop4h 00m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$144
Fort MyersKnoxville
RSW Fort Myers SW Florida Intl - TYS Knoxville McGhee Tyson
RSWTYS
Fort Myers SW Florida Intl
Thu 11/26
7:00 am-1:26 pm
1 stop6h 26m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$159
Fort MyersKnoxville
RSW Fort Myers SW Florida Intl - TYS Knoxville McGhee Tyson
RSWTYS
Fort Myers SW Florida Intl
Fri 11/13
9:20 am-8:35 pm
2 stops11h 15m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$187
Fort MyersKnoxville
RSW Fort Myers SW Florida Intl - TYS Knoxville McGhee Tyson
RSWTYS
Fort Myers SW Florida Intl
Fri 11/6
5:15 pm-11:23 am
3 stops42h 08m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$193
Fort MyersKnoxville
RSW Fort Myers SW Florida Intl - TYS Knoxville McGhee Tyson
RSWTYS
Fort Myers SW Florida Intl
Fri 11/20
5:30 am-9:55 am
1 stop4h 25m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$210
Fort MyersKnoxville
RSW Fort Myers SW Florida Intl - TYS Knoxville McGhee Tyson
RSWTYS
Fort Myers SW Florida Intl
Thu 11/5
7:25 am-4:50 pm
1 stop9h 25m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$215
Fort MyersKnoxville
RSW Fort Myers SW Florida Intl - TYS Knoxville McGhee Tyson
RSWTYS
Fort Myers SW Florida Intl
Sun 11/1
7:00 am-5:14 pm
3 stops58h 14m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$227
Fort MyersKnoxville
RSW Fort Myers SW Florida Intl - TYS Knoxville McGhee Tyson
RSWTYS
Fort Myers SW Florida Intl
Thu 11/5
7:00 am-10:05 pm
3 stops15h 05m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$228
Showing 1-10 of 23 resultsSorted by cheapest first
Compare providers for flights from Fort Myers to Knoxville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Fort Myers to Knoxville in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Fort Myers-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Fort Myers-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Fort Myers-Knoxville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Fort Myers-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Fort Myers-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Fort Myers to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from Fort Myers with our price prediction graph.
RSW-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Fort Myers to Knoxville
What is the cheapest month to book a flight from Fort Myers to Knoxville?
Currently, August is the cheapest month in which you can book a flight from Fort Myers to Knoxville (average of $268). Flying from Fort Myers to Knoxville in January is currently the most expensive (average of $715). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Fort Myers to Knoxville?
Airfare is below average for this route at the moment.
Fort Myers to Knoxville flights typically cost between $377 and $494 in November.The cheapest round-trip price found within the last 5 days was $229 on American Airlines (Nov 16-Nov 23).
Reviews of airlines servicing Knoxville
Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated October 19, 2026.
See what other customers who have flown with Delta and American Airlines from Fort Myers to Knoxville have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.8
Boarding
8.1
Crew
8.5
Overall
7.8
Entertainment
7.8
Food
7.2
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Comfort
7.8
Boarding
8.1
Crew
8.5
Overall
7.8
Entertainment
7.8
Food
7.2
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Comfort
7.8
Boarding
8.1
Crew
8.5
Overall
7.8
Entertainment
7.8
Food
7.2
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Related info for your journey
Find useful and relevant information for your journey from Fort Myers to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsCherokee
Crossville
Morristown
Newport
Bryson City
Murphy
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Other flights to Knoxville
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Fort Myers and Knoxville flights
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Top 2 airlines flying from Fort Myers to Knoxville
Discover the top 2 airlines that operate flights from Fort Myers to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 19, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$259 | Average$463 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$294 | Average$411 | FlexibilityNo cancel fee | On-timeN/A |