$349+ Cheap flights from Panama City to Knoxville (ECP - TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/9. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — TYS
Jul 31 — Aug 71

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Cheap flight deals from Panama City to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (ECP) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 26, 2024.

Popular in

March

Cheapest in

September

Round-trip from

$428
(Delta)

One-way from

$349
(Delta)
High demand for flights, 27% potential price rise
Best time to find cheap flights, 41% potential price drop
From Panama City NW Florida Beaches to Knoxville McGhee Tyson
One-way flight from Panama City NW Florida Beaches to Knoxville McGhee Tyson

What is the cheapest day to fly round-trip from Panama City, Florida to Knoxville?

Wednesday is generally a great day to depart. Flying on this day could help you save up to 90%.

What is the cheapest month to fly from Panama City, Florida to Knoxville?

September is one of the best times of the year to fly to Knoxville from Panama City, Florida. Prices for September average $501 per person but you can even find prices for as low as $288. The most expensive prices can be found in the month of March. Opting for a September flight can save you 36% on your journey compared to booking in March

What is the cheapest time of day to fly from ECP to TYS?

A simple way to save on the total cost of your ticket is to fly from Panama City, Florida to Knoxville in the morning. If you’re flexible enough to do this you can expect to save up to 18% on your trip compared to booking a flight at noon.

Cheap Panama City to Knoxville flights in July & August 2024

Find cheap flight options from Panama City to Knoxville specifically for the months of July and August 2024. Explore affordable fares based on user searches. Over the last 7 days, Cheapflights users made 2,751,780 searches. Prices were last updated on July 26, 2024.
These are some of the best deals we've found on flights to Knoxville in 2024 at this time. Check back regularly for other flight deals.
This Delta deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/232:29 pmECP - TYS
1 stop3h 32mDelta
Fri 8/306:33 pmTYS - ECP
1 stop6h 08mDelta
Deal found 7/25$428
This Delta deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/227:01 amECP - TYS
1 stop3h 08mDelta
Sun 8/255:25 amTYS - ECP
1 stop4h 03mDelta
Deal found 7/25$463
This Delta deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/97:01 amECP - TYS
1 stop3h 08mDelta
Mon 8/127:56 pmTYS - ECP
1 stop4h 45mDelta
Deal found 7/26$558
This United Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/222:17 pmECP - TYS
1 stop18h 56mUnited Airlines
Sun 8/257:20 pmTYS - ECP
2 stops17h 38mUnited Airlines
Deal found 7/25$585
This United Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/225:02 pmECP - TYS
2 stops29h 10mUnited Airlines
Sun 8/257:20 pmTYS - ECP
2 stops17h 38mUnited Airlines
Deal found 7/25$590
This Delta deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/84:59 pmECP - TYS
1 stop5h 52mDelta
Sun 8/115:25 amTYS - ECP
1 stop4h 03mDelta
Deal found 7/26$668
This United Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/236:40 amECP - TYS
2 stops29h 58mUnited Airlines
Fri 8/303:30 pmTYS - ECP
1 stop22h 56mUnited Airlines
Deal found 7/25$694
This United Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/235:02 pmECP - TYS
2 stops22h 41mUnited Airlines
Fri 8/305:55 pmTYS - ECP
2 stops23h 27mUnited Airlines
Deal found 7/25$747
This Delta deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/79:18 amECP - TYS
1 stop4h 39mDelta
Sat 8/104:02 pmTYS - ECP
1 stop4h 56mDelta
Deal found 7/26$758

Panama City to Knoxville 2024 flight deals

Discover exclusive flight deals for travel between Panama City and Knoxville in 2024. Find excellent offers based on user searches. Over the last 7 days, Cheapflights users made 2,751,780 searches. Data last updated July 26, 2024.
These are some of the best deals we've found on flights to Knoxville in 2024 at this time. Check back regularly for other flight deals.
This Delta deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/232:29 pmECP - TYS
1 stop3h 32mDelta
Fri 8/306:33 pmTYS - ECP
1 stop6h 08mDelta
Deal found 7/25$428
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/64:38 pmECP - TYS
1 stop3h 59mAmerican Airlines
Sun 9/85:30 amTYS - ECP
1 stop6h 16mAmerican Airlines
Deal found 7/25$455
This Delta deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/227:01 amECP - TYS
1 stop3h 08mDelta
Sun 8/255:25 amTYS - ECP
1 stop4h 03mDelta
Deal found 7/25$463
This Delta deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/86:00 amECP - TYS
1 stop4h 06mDelta
Thu 9/125:15 amTYS - ECP
1 stop4h 11mDelta
Deal found 7/26$533
This Delta deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/97:01 amECP - TYS
1 stop3h 08mDelta
Mon 8/127:56 pmTYS - ECP
1 stop4h 45mDelta
Deal found 7/26$558
This United Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/222:17 pmECP - TYS
1 stop18h 56mUnited Airlines
Sun 8/257:20 pmTYS - ECP
2 stops17h 38mUnited Airlines
Deal found 7/25$585
This United Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/225:02 pmECP - TYS
2 stops29h 10mUnited Airlines
Sun 8/257:20 pmTYS - ECP
2 stops17h 38mUnited Airlines
Deal found 7/25$590
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/610:45 amECP - TYS
1 stop7h 55mAmerican Airlines
Sun 9/88:26 pmTYS - ECP
2 stops14h 42mAmerican Airlines
Deal found 7/25$592
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/610:45 amECP - TYS
2 stops11h 46mAmerican Airlines
Sun 9/88:26 pmTYS - ECP
2 stops14h 42mAmerican Airlines
Deal found 7/25$597

Panama City to Knoxville flights leaving soon

Find last-minute flight options from Panama City to Knoxville for spontaneous travel. Discover available flights and compare prices based on user searches. Secure great deals and offers for spontaneous trips with quick booking options. Over the last 7 days, Cheapflights users made 2,751,780 searches. Data last updated July 26, 2024.
Have a look at some of the last-minute flights available departing from Panama City to Knoxville. It's wise to confirm all flight details are correct before booking.
This Delta deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/57:01 amECP - TYS
1 stop5h 18mDelta
Fri 8/97:56 pmTYS - ECP
1 stop4h 45mDelta
Deal found 7/26$768
This United deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/56:45 amECP - TYS
1 stop15h 40mUnited Airlines
Fri 8/94:45 pmTYS - ECP
2 stops28h 22mUnited Airlines
Deal found 7/26$890
This United deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/55:12 pmECP - TYS
2 stops19h 48mUnited Airlines
Fri 8/94:45 pmTYS - ECP
2 stops28h 22mUnited Airlines
Deal found 7/26$895

One-way flights to Knoxville from Panama City

Search for one-way flight options from Panama City to Knoxville. Find affordable one-way fares based on user searches. Compare prices and availability to plan your one-way journey according to your preferred dates and budget. Over the last 7 days, Cheapflights users made 2,751,780 searches. Data last updated July 26, 2024.
If you're seeking multiple options on one-way flights from Panama City to Knoxville, be sure to check out these deals, which are updated often. Users in need of a round-trip flight from Panama City to Knoxville instead should update the search form at the top of page.
This Delta deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/97:01 amECP - TYS
1 stop3h 08mDelta
Deal found 7/26$349
This Delta deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/44:59 pmECP - TYS
1 stop3h 57mDelta
Deal found 7/25$419
This United Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/96:45 amECP - TYS
2 stops26h 40mUnited Airlines
Deal found 7/26$569
This United Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/45:12 pmECP - TYS
2 stops28h 18mUnited Airlines
Deal found 7/25$602
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/912:50 pmECP - TYS
2 stops7h 17mAmerican Airlines
Deal found 7/25$629

Find flights from Panama City to Knoxville within your budget

Customize your flight search to find flights from Panama City to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,751,780 searches. Data last updated July 26, 2024.

Fly from

Any airport

Fly to

Any airport

Budget

$428 - $597

Route

Depart

Return

Price

Panama City NW Florida BeachesKnoxville McGhee Tyson

ECP - TYS

ECPTYS

Panama City NW Florida Beaches

Fri 8/23

1 stop3h 32m

Knoxville McGhee Tyson

Fri 8/30

1 stop6h 08m

$428

Panama City NW Florida BeachesKnoxville McGhee Tyson

ECP - TYS

ECPTYS

Panama City NW Florida Beaches

Fri 9/6

1 stop3h 59m

Knoxville McGhee Tyson

Sun 9/8

1 stop6h 16m

$455

Panama City NW Florida BeachesKnoxville McGhee Tyson

ECP - TYS

ECPTYS

Panama City NW Florida Beaches

Thu 8/22

1 stop3h 08m

Knoxville McGhee Tyson

Sun 8/25

1 stop4h 03m

$463

Panama City NW Florida BeachesKnoxville McGhee Tyson

ECP - TYS

ECPTYS

Panama City NW Florida Beaches

Sun 9/8

1 stop4h 06m

Knoxville McGhee Tyson

Thu 9/12

1 stop4h 11m

$533

Panama City NW Florida BeachesKnoxville McGhee Tyson

ECP - TYS

ECPTYS

Panama City NW Florida Beaches

Fri 8/9

1 stop3h 08m

Knoxville McGhee Tyson

Mon 8/12

1 stop4h 45m

$558

Panama City NW Florida BeachesKnoxville McGhee Tyson

ECP - TYS

ECPTYS

Panama City NW Florida Beaches

Thu 8/22

1 stop18h 56m

Knoxville McGhee Tyson

Sun 8/25

2 stops17h 38m

$585

Panama City NW Florida BeachesKnoxville McGhee Tyson

ECP - TYS

ECPTYS

Panama City NW Florida Beaches

Thu 8/22

2 stops29h 10m

Knoxville McGhee Tyson

Sun 8/25

2 stops17h 38m

$590

Panama City NW Florida BeachesKnoxville McGhee Tyson

ECP - TYS

ECPTYS

Panama City NW Florida Beaches

Fri 9/6

1 stop7h 55m

Knoxville McGhee Tyson

Sun 9/8

2 stops14h 42m

$592

Panama City NW Florida BeachesKnoxville McGhee Tyson

ECP - TYS

ECPTYS

Panama City NW Florida Beaches

Fri 9/6

2 stops11h 46m

Knoxville McGhee Tyson

Sun 9/8

2 stops14h 42m

$597

Flights are sorted by cheapest first

Deals found on 7/25

What is the cheapest day to fly from Panama City, Florida to Knoxville?

Use this chart to determine the cheapest time to fly round-trip from Panama City to Knoxville. Price data was last updated on July 21, 2024.
Morning
Noon
Afternoon
Evening
All times are departure.
Travelers seeking maximum savings on their Panama City, Florida to Knoxville flight should consider departing on Thursday mornings when fares are most often at their lowest. Friday at noon flights should be avoided if possible as fares are typically the most expensive at this time.
Search Deals

Best time to book a flight from Panama City to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Temperature and rainfall in Knoxville by month

Plan your trip to Knoxville by taking into account the average temperature and rainfall totals by month.

TYS

Temperature

39.2 - 78.8 °F

If weather is an important factor for your trip to Knoxville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 39.2 F).

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated July 26, 2024.
Peruse reviews from past customers who have flown with United Airlines, Delta and American Airlines from Panama City to Knoxville to help guide your decision. In addition to providing an overall rating, users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
8.0
Very good
9,615 reviews

Boarding

8.2

Comfort

7.9

Entertainment

8.0

Crew

8.6

Food

7.4

Overall

8.0

Reviews

1 / 10

When I was going to board, one of the staff members told me that I could not board with my passport bag because it was tree items and I would need to check a bag. This was so stupid ! The bag was small. So I had to put my things in my pockets, put the funny bag inside the other bag. Then go throw it. Then in the plane put everything back again in my funny bag.

8.0
Very good
9,615 reviews
8.0
Very good
9,615 reviews

Boarding

8.2

Comfort

7.9

Entertainment

8.0

Crew

8.6

Food

7.4

Overall

8.0

Reviews

1 / 10

When I was going to board, one of the staff members told me that I could not board with my passport bag because it was tree items and I would need to check a bag. This was so stupid ! The bag was small. So I had to put my things in my pockets, put the funny bag inside the other bag. Then go throw it. Then in the plane put everything back again in my funny bag.

7.4
Good
10,000 reviews
8.0
Very good
9,615 reviews

Boarding

8.2

Comfort

7.9

Entertainment

8.0

Crew

8.6

Food

7.4

Overall

8.0

Reviews

1 / 10

When I was going to board, one of the staff members told me that I could not board with my passport bag because it was tree items and I would need to check a bag. This was so stupid ! The bag was small. So I had to put my things in my pockets, put the funny bag inside the other bag. Then go throw it. Then in the plane put everything back again in my funny bag.

7.3
Good
10,000 reviews
8.0
Very good
9,615 reviews

Boarding

8.2

Comfort

7.9

Entertainment

8.0

Crew

8.6

Food

7.4

Overall

8.0

Reviews

1 / 10

When I was going to board, one of the staff members told me that I could not board with my passport bag because it was tree items and I would need to check a bag. This was so stupid ! The bag was small. So I had to put my things in my pockets, put the funny bag inside the other bag. Then go throw it. Then in the plane put everything back again in my funny bag.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • Can I find flights from Panama City, Florida to Knoxville for under $500 on Cheapflights?

    Yes, there are multiple flights from Panama City, Florida to Knoxville for under $500. The cheapest flight booked recently is on Delta for just $428, but on average you can expect to pay $666.

  • Are there last-minute flights available from Panama City, Florida to Knoxville for under $800?

    There are currently 3+ open flights from Panama City, Florida to Knoxville within the next 7 days for less than $800.

  • What are the cheapest airlines flying from Panama City, Florida to Knoxville round-trip?

    Our cheapest airline available from Panama City, Florida to Knoxville is Delta. Our recent data shows that you can find tickets from as low as $428 on this airline. Additional options worth looking into are American Airlines and United Airlines, starting at $455 and $585 round-trip. You may be able to fly from Panama City, Florida to Knoxville for 14% less than the average price by searching for these airlines.

  • What are the cheapest airlines to fly from Panama City, Florida to Knoxville one-way?

    The cheapest airline one-way is Delta, with whom users have recently found tickets for as low as $349. However, be on the lookout for offers from United Airlines and American Airlines, as they are both options that can get you from Panama City, Florida to Knoxville for a low price.

  • What does ECP to TYS mean?

    Great question - ECP to TYS just means Panama City NW Florida Beaches Airport to Knoxville McGhee Tyson Airport. Now you’ll know what these unique codes when you look for flights!

  • Can I find deals for flights from Panama City to Knoxville that include extra baggage allowance?

    The amount of baggage you can bring on your Panama City to Knoxville flight depends on the airline and the type of fare you've chosen. After entering your flight details, you'll be able to view the specific baggage policies for each deal in the search results. Keep in mind that certain deals may offer additional baggage allowance.

  • Can I find deals on flights from Panama City to Knoxville with specific airlines?

    Yes, Cheapflights allows you to browse and filter Panama City to Knoxville flight deals by airline. After entering your origin and destination, use the available filters to view flights offered by airlines.

  • Can I find deals for flights from Panama City to Knoxville that include hotel bookings?

    Yes. In addition to deals on Panama City to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Knoxville.

  • Can I find deals for business class flights from Panama City to Knoxville?

    Yes. Cheapflights offers flight deals from Panama City to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • Can I find deals for flights from Panama City to Knoxville that allow pets onboard?

    Many airlines flying from Panama City to Knoxville offer the option to travel with pets. After selecting a flight deal, you can find more information about the airline's pet policy on their official website or by contacting the airline directly. Please note that additional fees and restrictions may apply.

  • Can I find deals on last-minute flights from Panama City to Knoxville?

    Yes, you can often find last-minute deals on Panama City to Knoxville flights on Cheapflights. However, these deals can vary and may not always be available. We recommend checking back frequently or signing up for price alerts for the most up-to-date deals.

  • How recently were the Panama City, Florida to Knoxville flight deals updated?

    The Panama City, Florida to Knoxville flight deals you see on this page were last updated on 7/26.

  • What is the cheapest month to book a flight from Panama City, Florida to Knoxville?

    Currently, December is the cheapest month in which you can book a flight from Panama City, Florida to Knoxville (average of $297). Flying from Panama City, Florida to Knoxville in April is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Panama City to Knoxville
See prices for flight routes from nearby airports that may be better suited for you.

Top 2 airlines flying from Panama City to Knoxville

Discover the top 2 airlines that operate flights from Panama City to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,751,780 searches. Data last updated July 26, 2024.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$305Average$476FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$411Average$655FlexibilityNo cancel feeOn-time71%

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