Cheap flights from Knoxville to Panama City (TYS - ECP) from $375

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/21. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
TYS — ECP
Apr 28 — May 51

The best prices from Knoxville McGhee Tyson to Panama City NW Florida Beaches are usually found in January or August, booked 25 days in advance, depart on a Tuesday or Friday and return on a Wednesday

Cheap flight deals from Knoxville to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Panama City (ECP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 23, 2024.

Popular in

April

Cheapest in

January

Average price

$736

Round-trip from

$331
High demand for flights, 33% potential price rise
Best time to find cheap flights, 29% potential price drop
Average for round-trip flights in April 2024
From Knoxville McGhee Tyson to Panama City NW Florida Beaches

What is the cheapest day to fly round-trip from Knoxville to Panama City, Florida?

Wednesday flights are found to be more expensive to fly from Knoxville to Panama City, Florida. This shouldn’t discourage you from searching, as you can still find great deals by being flexible with your options. Use our search form to find deals on tickets to Panama City, Florida.

How far in advance should I book a flight from Knoxville to Panama City, Florida?

Users have found that booking a flight from Knoxville to Panama City, Florida at least 26 days early can save you up to 128% on average compared to booking a flight this week. If booking 26 days before your flight isn’t an option for you, users have found flights from Knoxville to Panama City, Florida for as little as $492 when booking for a departure date within the next two weeks. You can also check prices now. Some users have found airline tickets as low as $492 for flights departing within the next 3 days.

What is the cheapest month to fly from Knoxville to Panama City, Florida?

Flights from Knoxville to Panama City, Florida lean towards being more expensive in April. Prices are generally better when you fly from Knoxville to Panama City, Florida in January, with the cheapest ticket starting at $232.

When is the cheapest time to fly from Knoxville to Panama City, Florida (TYS - ECP)?

It’s typically best to fly out from Knoxville to Panama City, Florida in the evening. Doing so could potentially save you 51% on the flight price compared to flying at noon, which is usually more expensive.

Cheap American Airlines flights from Knoxville to Panama City

Explore cheap flight options specifically provided by American Airlines for the route between Knoxville and Panama City. Find affordable fares and compare prices with other airlines to secure the best deal for your journey. Over the last 7 days, Cheapflights users made 3,073,952 searches. Data last updated April 23, 2024.
Take a look at some of the lowest-priced American Airlines flights heading from Knoxville to Panama City. It's recommended that users confirm their flight details before booking.
Wed 8/2111:15 amTYS - ECP
1 stop4h 56mAmerican Airlines
Tue 8/2711:00 amECP - TYS
1 stop3h 46mAmerican Airlines
Deal found 4/22$375
Wed 8/216:16 amTYS - ECP
2 stops9h 55mAmerican Airlines
Tue 8/274:58 pmECP - TYS
1 stop3h 26mAmerican Airlines
Deal found 4/22$415
Sun 5/266:20 amTYS - ECP
1 stop10h 11mAmerican Airlines
Thu 5/3010:04 amECP - TYS
2 stops9h 32mAmerican Airlines
Deal found 4/22$447
Fri 6/712:44 pmTYS - ECP
1 stop6h 45mAmerican Airlines
Sun 6/92:31 pmECP - TYS
1 stop3h 29mAmerican Airlines
Deal found 4/22$475
Sat 7/65:10 amTYS - ECP
1 stop5h 43mAmerican Airlines
Wed 7/102:31 pmECP - TYS
2 stops8h 28mAmerican Airlines
Deal found 4/21$480
Wed 8/216:16 amTYS - ECP
2 stops9h 55mAmerican Airlines
Tue 8/271:09 pmECP - TYS
2 stops7h 22mAmerican Airlines
Deal found 4/22$485
Fri 5/105:19 amTYS - ECP
1 stop5h 05mAmerican Airlines
Sat 5/1110:04 amECP - TYS
1 stop6h 22mAmerican Airlines
Deal found 4/23$535
Fri 5/105:19 amTYS - ECP
1 stop5h 05mAmerican Airlines
Sat 5/112:30 pmECP - TYS
2 stops8h 12mAmerican Airlines
Deal found 4/23$540
Fri 5/107:00 amTYS - ECP
2 stops8h 00mAmerican Airlines
Sat 5/112:30 pmECP - TYS
2 stops8h 12mAmerican Airlines
Deal found 4/23$576

Cheap United Airlines flights from Knoxville to Panama City

Explore cheap flight options specifically provided by United Airlines for the route between Knoxville and Panama City. Find affordable fares and compare prices with other airlines to secure the best deal for your journey. Over the last 7 days, Cheapflights users made 3,073,952 searches. Data last updated April 23, 2024.
Have a look at some of the cheapest available United Airlines flights departing from Knoxville and landing in Panama City. Make sure to examine the flight information before completing your reservation.
Sat 5/257:05 pmTYS - ECP
2 stops22h 12mUnited Airlines
Wed 5/295:05 pmECP - TYS
2 stops28h 31mUnited Airlines
Deal found 4/22$666
Thu 8/294:48 pmTYS - ECP
2 stops21h 38mUnited Airlines
Mon 9/22:17 pmECP - TYS
2 stops23h 23mUnited Airlines
Deal found 4/22$689
Thu 8/297:05 pmTYS - ECP
1 stop19h 21mUnited Airlines
Mon 9/22:17 pmECP - TYS
2 stops23h 23mUnited Airlines
Deal found 4/22$709
Tue 5/215:33 pmTYS - ECP
2 stops27h 31mUnited Airlines
Tue 5/286:52 amECP - TYS
2 stops30h 05mUnited Airlines
Deal found 4/21$764
Mon 5/205:33 pmTYS - ECP
2 stops27h 33mUnited Airlines
Sat 5/252:10 pmECP - TYS
2 stops23h 30mUnited Airlines
Deal found 4/21$806

Cheap Knoxville to Panama City flights in April & May 2024

Find cheap flight options from Knoxville to Panama City specifically for the months of April and May 2024. Explore affordable fares based on user searches. Over the last 7 days, Cheapflights users made 3,073,952 searches. Prices were last updated on April 23, 2024.
Listed are some of the best fares we've found on flights departing from Knoxville to Panama City in 2024. For more flight deals, be sure to check back very soon.
Sun 5/2610:21 amTYS - ECP
1 stop4h 21mDelta
Thu 5/309:16 amECP - TYS
1 stop3h 17mDelta
Deal found 4/23$378
Thu 5/303:45 pmTYS - ECP
1 stop3h 46mDelta
Sun 6/26:00 amECP - TYS
1 stop3h 11mDelta
Deal found 4/22$428
Sun 5/266:20 amTYS - ECP
1 stop10h 11mAmerican Airlines
Thu 5/3010:04 amECP - TYS
2 stops9h 32mAmerican Airlines
Deal found 4/22$447
Sun 5/129:08 amTYS - ECP
1 stop5h 34mDelta
Sun 5/196:00 amECP - TYS
1 stop3h 11mDelta
Deal found 4/23$518
Fri 5/105:19 amTYS - ECP
1 stop5h 05mAmerican Airlines
Sat 5/1110:04 amECP - TYS
1 stop6h 22mAmerican Airlines
Deal found 4/23$535
Fri 5/105:19 amTYS - ECP
1 stop5h 05mAmerican Airlines
Sat 5/112:30 pmECP - TYS
2 stops8h 12mAmerican Airlines
Deal found 4/23$540
Fri 5/107:00 amTYS - ECP
2 stops8h 00mAmerican Airlines
Sat 5/112:30 pmECP - TYS
2 stops8h 12mAmerican Airlines
Deal found 4/23$576
Mon 5/205:19 amTYS - ECP
1 stop5h 05mAmerican Airlines
Sat 5/257:13 pmECP - TYS
1 stop3h 38mAmerican Airlines
Deal found 4/21$595
Thu 5/167:01 amTYS - ECP
1 stop3h 23mAmerican Airlines
Sun 5/267:10 pmECP - TYS
1 stop3h 41mAmerican Airlines
Deal found 4/22$605

Knoxville to Panama City 2024 flight deals

Discover exclusive flight deals for travel between Knoxville and Panama City in 2024. Find excellent offers based on user searches. Over the last 7 days, Cheapflights users made 3,073,952 searches. Data last updated April 23, 2024.
Listed are some of the best fares we've found on flights departing from Knoxville to Panama City in 2024. For more flight deals, be sure to check back very soon.
Wed 8/2111:15 amTYS - ECP
1 stop4h 56mAmerican Airlines
Tue 8/2711:00 amECP - TYS
1 stop3h 46mAmerican Airlines
Deal found 4/22$375
Sun 5/2610:21 amTYS - ECP
1 stop4h 21mDelta
Thu 5/309:16 amECP - TYS
1 stop3h 17mDelta
Deal found 4/23$378
Wed 8/216:16 amTYS - ECP
2 stops9h 55mAmerican Airlines
Tue 8/274:58 pmECP - TYS
1 stop3h 26mAmerican Airlines
Deal found 4/22$415
Thu 5/303:45 pmTYS - ECP
1 stop3h 46mDelta
Sun 6/26:00 amECP - TYS
1 stop3h 11mDelta
Deal found 4/22$428
Sun 5/266:20 amTYS - ECP
1 stop10h 11mAmerican Airlines
Thu 5/3010:04 amECP - TYS
2 stops9h 32mAmerican Airlines
Deal found 4/22$447
Sat 7/65:25 amTYS - ECP
1 stop3h 59mDelta
Wed 7/106:01 pmECP - TYS
1 stop4h 52mDelta
Deal found 4/22$458
Fri 6/712:44 pmTYS - ECP
1 stop6h 45mAmerican Airlines
Sun 6/92:31 pmECP - TYS
1 stop3h 29mAmerican Airlines
Deal found 4/22$475
Sat 7/65:10 amTYS - ECP
1 stop5h 43mAmerican Airlines
Wed 7/102:31 pmECP - TYS
2 stops8h 28mAmerican Airlines
Deal found 4/21$480
Wed 8/216:16 amTYS - ECP
2 stops9h 55mAmerican Airlines
Tue 8/271:09 pmECP - TYS
2 stops7h 22mAmerican Airlines
Deal found 4/22$485

One-way flights to Panama City from Knoxville

Search for one-way flight options from Knoxville to Panama City. Find affordable one-way fares based on user searches. Compare prices and availability to plan your one-way journey according to your preferred dates and budget. Over the last 7 days, Cheapflights users made 3,073,952 searches. Data last updated April 23, 2024.
Take a look at some of the best available options we've come across on one-way flights from Knoxville to Panama City. Those needing a return flight from Knoxville to Panama City can use the search form above.
Sat 5/41:18 pmTYS - ECP
1 stop23h 32mUnited Airlines
Deal found 4/21$383
Sat 5/410:51 amTYS - ECP
2 stops30h 20mUnited Airlines
Deal found 4/21$388
Fri 5/39:03 amTYS - ECP
1 stop4h 19mAmerican Airlines
Deal found 4/22$408
Fri 5/37:00 amTYS - ECP
2 stops8h 04mAmerican Airlines
Deal found 4/22$414

Find flights from Knoxville to Panama City within your budget

Customize your flight search to find flights from Knoxville to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 3,073,952 searches. Data last updated April 23, 2024.

Fly from

Any airport

Fly to

Any airport

Budget

$375 - $666

Route

Depart

Return

Price

Knoxville McGhee TysonPanama City NW Florida Beaches

TYS - ECP

TYSECP

Knoxville McGhee Tyson

Wed 8/21

1 stop4h 56m

Panama City NW Florida Beaches

Tue 8/27

1 stop3h 46m

$375

Knoxville McGhee TysonPanama City NW Florida Beaches

TYS - ECP

TYSECP

Knoxville McGhee Tyson

Sun 5/26

1 stop4h 21m

Panama City NW Florida Beaches

Thu 5/30

1 stop3h 17m

$378

Knoxville McGhee TysonPanama City NW Florida Beaches

TYS - ECP

TYSECP

Knoxville McGhee Tyson

Wed 8/21

2 stops9h 55m

Panama City NW Florida Beaches

Tue 8/27

1 stop3h 26m

$415

Knoxville McGhee TysonPanama City NW Florida Beaches

TYS - ECP

TYSECP

Knoxville McGhee Tyson

Thu 5/30

1 stop3h 46m

Panama City NW Florida Beaches

Sun 6/2

1 stop3h 11m

$428

Knoxville McGhee TysonPanama City NW Florida Beaches

TYS - ECP

TYSECP

Knoxville McGhee Tyson

Sun 5/26

1 stop10h 11m

Panama City NW Florida Beaches

Thu 5/30

2 stops9h 32m

$447

Knoxville McGhee TysonPanama City NW Florida Beaches

TYS - ECP

TYSECP

Knoxville McGhee Tyson

Sat 7/6

1 stop3h 59m

Panama City NW Florida Beaches

Wed 7/10

1 stop4h 52m

$458

Knoxville McGhee TysonPanama City NW Florida Beaches

TYS - ECP

TYSECP

Knoxville McGhee Tyson

Fri 6/7

1 stop6h 45m

Panama City NW Florida Beaches

Sun 6/9

1 stop3h 29m

$475

Knoxville McGhee TysonPanama City NW Florida Beaches

TYS - ECP

TYSECP

Knoxville McGhee Tyson

Sun 5/12

1 stop5h 34m

Panama City NW Florida Beaches

Sun 5/19

1 stop3h 11m

$518

Knoxville McGhee TysonPanama City NW Florida Beaches

TYS - ECP

TYSECP

Knoxville McGhee Tyson

Sat 5/25

2 stops22h 12m

Panama City NW Florida Beaches

Wed 5/29

2 stops28h 31m

$666

Flights are sorted by cheapest first

Deals found on 4/22

When is the best time to book a flight from Knoxville to Panama City, Florida?

Use this chart to determine the optimal time to book a round-trip flight from Knoxville to Panama City. Price data was last updated on January 28, 2024.
The price you pay for your flight from Knoxville to Panama City, Florida may vary depending on when you book. For the best chance of a lower fare, look to book 25 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
Search Deals

When is the cheapest time to fly from Knoxville to Panama City, Florida?

Use this chart to determine the cheapest time to fly round-trip from Knoxville to Panama City. Price data was last updated on April 21, 2024.
Morning
Noon
Afternoon
Evening
All times are departure.
Travelers seeking maximum savings on their Knoxville to Panama City, Florida flight should consider departing on Wednesday mornings when fares are most often at their lowest. Wednesday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.
Search Deals

Average price of flights to Panama City by month

Plan your trip from Knoxville to Panama City by taking into account the cheapest months to travel. The average price of a one-way flight from Knoxville to Panama City is currently $398 while a round-trip flight costs $462. Price data was last updated on April 21, 2024.

Currently, January is the cheapest month in which you can book a flight from Knoxville to Panama City, Florida (average of $331). Flying from Knoxville to Panama City, Florida in May is currently the most expensive (average of $437). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

January

$331

February

$377

March

$415

April

$423

May

$437

June

$432

July

$396

August

$376

September

$378

October

$370

November

$386

December

$348

Temperature and rainfall in Panama City by month

Plan your trip to Panama City by taking into account the average temperature and rainfall totals by month.

ECP

Temperature

53.6 - 80.6 °F

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated April 23, 2024.
To help decide which airline to fly from Knoxville to Panama City, see what other customers have to say about American Airlines, United Airlines and Delta. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
8.1
Very good
11,028 reviews

Overall

8.1

Boarding

8.2

Food

7.5

Entertainment

8.0

Comfort

7.9

Crew

8.6

Reviews

1 / 10

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.

8.1
Very good
11,028 reviews
8.1
Very good
11,028 reviews

Overall

8.1

Boarding

8.2

Food

7.5

Entertainment

8.0

Comfort

7.9

Crew

8.6

Reviews

1 / 10

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.

7.4
Good
11,272 reviews
8.1
Very good
11,028 reviews

Overall

8.1

Boarding

8.2

Food

7.5

Entertainment

8.0

Comfort

7.9

Crew

8.6

Reviews

1 / 10

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.

7.3
Good
14,914 reviews
8.1
Very good
11,028 reviews

Overall

8.1

Boarding

8.2

Food

7.5

Entertainment

8.0

Comfort

7.9

Crew

8.6

Reviews

1 / 10

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • Can I find flights from Knoxville to Panama City, Florida for under $400 on Cheapflights?

    Yes, there are multiple flights from Knoxville to Panama City, Florida for under $400. The cheapest flight booked recently is on American Airlines for just $375, but on average you can expect to pay $516.

  • What are the cheapest airlines flying from Knoxville to Panama City, Florida round-trip?

    Our cheapest airline available from Knoxville to Panama City, Florida is American Airlines. Our recent data shows that you can find tickets from as low as $375 on this airline. Additional options worth looking into are Delta and United Airlines, starting at $378 and $666 round-trip. You may be able to fly from Knoxville to Panama City, Florida for 23% less than the average price by searching for these airlines.

  • What does TYS to ECP mean?

    TYS and ECP are unique codes to identify airports used in the aviation industry. They are defined by IATA (International Air Transport Association) and are commonly called IATA codes. TYS to ECP refers to a flight route from Knoxville McGhee Tyson Airport to Panama City NW Florida Beaches Airport.

  • Can I find deals for flights from Knoxville to Panama City that include extra baggage allowance?

    The amount of baggage you can bring on your Knoxville to Panama City flight depends on the airline and the type of fare you've chosen. After entering your flight details, you'll be able to view the specific baggage policies for each deal in the search results. Keep in mind that certain deals may offer additional baggage allowance.

  • Can I find deals on flights from Knoxville to Panama City with specific airlines?

    Yes, Cheapflights allows you to browse and filter Knoxville to Panama City flight deals by airline. After entering your origin and destination, use the available filters to view flights offered by airlines.

  • Can I find deals for flights from Knoxville to Panama City that include hotel bookings?

    Yes. In addition to deals on Knoxville to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Panama City.

  • Can I find deals for business class flights from Knoxville to Panama City?

    Yes. Cheapflights offers flight deals from Knoxville to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • Can I find deals for flights from Knoxville to Panama City that allow pets onboard?

    Many airlines flying from Knoxville to Panama City offer the option to travel with pets. After selecting a flight deal, you can find more information about the airline's pet policy on their official website or by contacting the airline directly. Please note that additional fees and restrictions may apply.

  • Can I find deals on last-minute flights from Knoxville to Panama City?

    Yes, you can often find last-minute deals on Knoxville to Panama City flights on Cheapflights. However, these deals can vary and may not always be available. We recommend checking back frequently or signing up for price alerts for the most up-to-date deals.

  • How recently were the Knoxville to Panama City, Florida flight deals updated?

    The Knoxville to Panama City, Florida flight deals you see on this page were last updated on 4/23.

See more FAQs

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Alternative routes for Knoxville to Panama City
See prices for flight routes from nearby airports that may be better suited for you.

Top 2 airlines flying from Knoxville to Panama City

Discover the top 2 airlines that operate flights from Knoxville to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 3,073,952 searches. Data last updated April 23, 2024.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$296Average$494FlexibilityNo cancel feeOn-timeN/A
Search Delta flights
American AirlinesCheapest$384Average$575FlexibilityNo cancel feeOn-time71%
Search American Airlines flights

Search flights from Knoxville to Panama City by cabin class

Find flights from Knoxville to Panama City, based on your preferred cabin class, be it economy, premium economy, business, or first class.

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travelers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Knoxville to Panama City?

Cheapflights goes through 900+ travel sites to look for the best flight deals for flights from Knoxville to Panama City. Too many options? Cheapflights also provides filters for things like airlines, price ranges, and number of stops to help you make a decision easily.

Why should you use Cheapflights to find cheap flight tickets from Knoxville to Panama City?

By finding flights from multiple airlines and providers at completely no cost, Cheapflights helps millions of users like you annually find the best flights to Panama City from Knoxville.

Can Cheapflights find flights from Knoxville to Panama City with no change fees?

Certainly. Search results for flights to Panama City from Knoxville shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

Can Cheapflights notify me if prices for flights from Knoxville to Panama City become cheaper?

Yes, Cheapflights has a feature called Price Alert, which notifies users when flight prices change. Track prices for your flight to Panama City from Knoxville today and book when prices fit your budget.

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