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Knoxville

$41+ Cheap flights from Tampa to Knoxville (PIE - TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/29. Fares are subject to change and may not be available on all flights or dates of travel.
PIE — TYS
Jun 8 — Jun 151
Mon 6/8
Mon 6/15
1 adult, Economy
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Find cheap flights from St Petersburg to Knoxville with Cheapflights

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Cheapflights Tip: The best prices from Tampa St. Petersburg to Knoxville McGhee Tyson are usually found in August or June, booked 50 days in advance, depart on a Saturday or Monday and return on a Thursday

Cheap flight deals from St Petersburg to Knoxville

Cheapest flights from St Petersburg to Knoxville
Explore the most affordable flight options available from St Petersburg to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 9, 2026.

This Cheapflightsfares deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/18:50 pm
PIE
-
TYS
Nonstop1h 41m
Allegiant Air
Wed 6/108:00 am
TYS
-
PIE
Nonstop1h 40m
Allegiant Air
Deal found 5/5$79
This Cheapflightsfares deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/98:42 pm
PIE
-
TYS
Nonstop1h 41m
Allegiant Air
Mon 7/137:04 pm
TYS
-
PIE
Nonstop1h 44m
Allegiant Air
Deal found 5/6$82
This Cheapflightsfares deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/298:50 pm
PIE
-
TYS
Nonstop1h 41m
Allegiant Air
Mon 6/18:00 am
TYS
-
PIE
Nonstop1h 40m
Allegiant Air
Deal found 5/5$85
This Cheapflightsfares deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/238:16 pm
PIE
-
TYS
Nonstop1h 41m
Allegiant Air
Tue 5/2611:31 am
TYS
-
PIE
Nonstop1h 40m
Allegiant Air
Deal found 5/4$86
This Cheapflightsfares deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/238:16 pm
PIE
-
TYS
Nonstop1h 41m
Allegiant Air
Fri 5/296:20 pm
TYS
-
PIE
Nonstop1h 40m
Allegiant Air
Deal found 5/5$91
This Cheapflightsfares deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/48:34 pm
PIE
-
TYS
Nonstop1h 42m
Allegiant Air
Sat 6/66:41 pm
TYS
-
PIE
Nonstop1h 40m
Allegiant Air
Deal found 5/5$93
This Cheapflightsfares deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/264:52 pm
PIE
-
TYS
Nonstop1h 41m
Allegiant Air
Fri 5/296:20 pm
TYS
-
PIE
Nonstop1h 40m
Allegiant Air
Deal found 5/6$98
This Cheapflightsfares deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2710:30 am
PIE
-
TYS
Nonstop1h 41m
Allegiant Air
Fri 5/296:20 pm
TYS
-
PIE
Nonstop1h 40m
Allegiant Air
Deal found 5/7$103
This Cheapflightsfares deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/2410:45 am
PIE
-
TYS
Nonstop1h 41m
Allegiant Air
Wed 5/278:00 am
TYS
-
PIE
Nonstop1h 40m
Allegiant Air
Deal found 5/8$104
This Cheapflightsfares deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/279:13 pm
PIE
-
TYS
Nonstop1h 42m
Allegiant Air
Sat 7/46:42 pm
TYS
-
PIE
Nonstop1h 44m
Allegiant Air
Deal found 5/9$107

Find flight deals from St Petersburg to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from St Petersburg (PIE) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 9, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$79
(Cheapflightsfares)

One-way from

$41
(Kiwi.com)

Popular in

November

Cheapest in

August

Average price

$170
Provider with most accurate pricing for Tampa St. Petersburg-Knoxville McGhee Tyson flight deals.
Search Deals
Provider most trusted by Cheapflights users for Tampa St. Petersburg-Knoxville McGhee Tyson flights.
Search Deals
From Tampa St. Petersburg to Knoxville McGhee Tyson
Search Deals
One-way flight from Tampa St. Petersburg to Knoxville McGhee Tyson
Search Deals
Highest demand for flights based on searches. 16% potential increase in price ($33 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($6 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in May 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from St Petersburg to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 9, 2026.
Use the filters below to find and compare flights from Tampa to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

TampaKnoxville

PIE - TYS

PIETYS

Tampa St. Petersburg

Tue 5/26

4:52 pm-6:33 pm

Nonstop1h 41m

Knoxville McGhee Tyson

Fri 5/29

6:20 pm-8:00 pm

Nonstop1h 40m

$98

TampaKnoxville

PIE - TYS

PIETYS

Tampa St. Petersburg

Sun 5/24

10:45 am-12:26 pm

Nonstop1h 41m

Knoxville McGhee Tyson

Tue 5/26

2:22 pm-4:02 pm

Nonstop1h 40m

$108

TampaKnoxville

PIE - TYS

PIETYS

Tampa St. Petersburg

Thu 5/28

4:56 pm-6:37 pm

Nonstop1h 41m

Knoxville McGhee Tyson

Mon 6/1

8:00 am-9:40 am

Nonstop1h 40m

$110

TampaKnoxville

PIE - TYS

PIETYS

Tampa St. Petersburg

Mon 8/10

9:49 pm-11:31 pm

Nonstop1h 42m

Knoxville McGhee Tyson

Thu 8/13

6:09 pm-7:53 pm

Nonstop1h 44m

$110

TampaKnoxville

PIE - TYS

PIETYS

Tampa St. Petersburg

Wed 7/15

10:34 am-12:15 pm

Nonstop1h 41m

Knoxville McGhee Tyson

Sun 7/19

8:15 am-9:59 am

Nonstop1h 44m

$118

TampaKnoxville

PIE - TYS

PIETYS

Tampa St. Petersburg

Fri 6/26

9:30 pm-11:12 pm

Nonstop1h 42m

Knoxville McGhee Tyson

Sun 6/28

8:15 am-9:55 am

Nonstop1h 40m

$123

TampaKnoxville

PIE - TYS

PIETYS

Tampa St. Petersburg

Thu 5/28

4:56 pm-6:37 pm

Nonstop1h 41m

Knoxville McGhee Tyson

Sun 5/31

7:27 pm-9:07 pm

Nonstop1h 40m

$129

TampaKnoxville

PIE - TYS

PIETYS

Tampa St. Petersburg

Sun 6/7

8:34 pm-10:16 pm

Nonstop1h 42m

Knoxville McGhee Tyson

Sun 6/14

8:15 am-9:55 am

Nonstop1h 40m

$137

TampaKnoxville

PIE - TYS

PIETYS

Tampa St. Petersburg

Fri 6/26

9:30 pm-11:12 pm

Nonstop1h 42m

Knoxville McGhee Tyson

Mon 7/6

7:04 pm-8:48 pm

Nonstop1h 44m

$137
Quickest round-trip

TampaKnoxville

PIE - TYS

PIETYS

Tampa St. Petersburg

Mon 10/12

6:45 am-8:23 am

Nonstop1h 38m

Knoxville McGhee Tyson

Fri 10/16

9:41 pm-11:20 pm

Nonstop1h 39m

$142

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/5

Showing 1-10 of 19 resultsSorted by cheapest first
1
2

Compare providers for flights from St Petersburg to Knoxville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from St Petersburg to Knoxville in May.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
CheapflightsfaresPrice Accuracy2 starsTrust Score*1 star
eDreamsPrice Accuracy2 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Tampa-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Tampa-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Tampa-Knoxville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Tampa-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Tampa-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from St Petersburg to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from St Petersburg with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Tampa to Knoxville

How far ahead should I book a flight from Tampa to Knoxville?

To ensure you get the cheapest price possible for a flight from Tampa to Knoxville, you should look to book at least 49 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Tampa to Knoxville?

Currently, August is the cheapest month in which you can book a flight from Tampa to Knoxville (average of $124). Flying from Tampa to Knoxville in November is currently the most expensive (average of $233). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PIE to TYS?

Find hourly flight availability from St Petersburg to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 9, 2026.

One of the essential ways to save on airfare from Tampa to Knoxville is to remain as flexible as possible. Flights that are in the afternoon tend to be the most expensive. A flight in the evening could potentially save you up to 26% on airfare.

What is the cheapest day to fly from Tampa to Knoxville?

Use this chart to determine the cheapest time to fly round-trip from St Petersburg to Knoxville. Price data was last updated on May 9, 2026.

Travelers seeking maximum savings on their Tampa to Knoxville flight should consider departing on Monday evenings when fares are most often at their lowest. Sunday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

How much does it cost to fly round-trip from Tampa to Knoxville?

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated May 9, 2026.
Read through reviews of airlines operating flights from Tampa to Knoxville, such as Allegiant Air. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Allegiant Air
7.3
Good
709 reviews

Comfort

6.9

Crew

8.1

Boarding

7.6

Overall

7.3

Food

5.8

Entertainment

5.5

Reviews

1 / 20
2.0
Mediocre

larry,Apr 2026

PSC - SNA

After waiting more than 6 hours our flight was delayed until the next day. The flight was extremely uncomfortable. Like riding on hard plastic lawn chairs in the sky.
Allegiant Air
7.3
Good
709 reviews
Allegiant Air
7.3
Good
709 reviews

Comfort

6.9

Crew

8.1

Boarding

7.6

Overall

7.3

Food

5.8

Entertainment

5.5

Reviews

1 / 20
2.0
Mediocre

larry,Apr 2026

PSC - SNA

After waiting more than 6 hours our flight was delayed until the next day. The flight was extremely uncomfortable. Like riding on hard plastic lawn chairs in the sky.

Related info for your journey

Find useful and relevant information for your journey from St Petersburg to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Tampa to Knoxville flight route?

    The Tampa St. Petersburg to Knoxville McGhee Tyson flight path was viewed by 7 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Tampa to Knoxville?

    Departing from Tampa to Knoxville will take you 1h 41m. The distance between Tampa and Knoxville is about 551 mi. Most flights are nonstop.

  • What is the cheapest airline to fly from Tampa to Knoxville round-trip?

    Currently priced at $87, Allegiant Air will fly you from Tampa to Knoxville and back. In addition to Allegiant Air, many other airlines offer competitively priced options for your trip. This flight start at 49% lower than the current average price 3 months from now.

  • What are the cheapest flights from Tampa to Knoxville?

    On average you can expect to pay $136 for a flight from Tampa to Knoxville. The cheapest flight overall is $64 while the most popular route, (Tampa St. Petersburg - Knoxville McGhee Tyson) is currently priced at $82.

  • Can I find deals for flights from St Petersburg to Knoxville that include hotel bookings?

    Yes. In addition to deals on St Petersburg to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St Petersburg to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St Petersburg to Knoxville.

  • Can I find deals for business class flights from St Petersburg to Knoxville?

    Yes. Cheapflights offers flight deals from St Petersburg to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Tampa to Knoxville?

    Currently, August is the cheapest month in which you can book a flight from Tampa to Knoxville (average of $124). Flying from Tampa to Knoxville in November is currently the most expensive (average of $233). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Cherokee
Crossville
Morristown
Bryson City
Murphy
Alcoa
Oak Ridge

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Top airline flying from St Petersburg to Knoxville

Discover the top airline that operate flights from St Petersburg to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 9, 2026.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$87Average$170FlexibilityNo cancel feeOn-time88%

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