HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Knoxville

$46+ Cheap flights from Tampa to Knoxville (PIE - TYS)

PIE — TYS
Oct 23 — Oct 301
Fri 10/23
Fri 10/30
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from St Petersburg to Knoxville with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.
Cheapflights Tip: The best prices from Tampa St. Petersburg to Knoxville McGhee Tyson are usually found in August or June, booked 33 days in advance, depart on a Tuesday or Monday and return on a Wednesday

Cheap flight deals from St Petersburg to Knoxville

Cheapest flights from St Petersburg to Knoxville

Sun 10/46:35 am -
Nonstop1h 38m
Thu 10/159:28 pm -
Nonstop1h 39m
Deal found 9/21$85
Sun 10/46:35 am -
Nonstop1h 38m
Fri 10/169:41 pm -
Nonstop1h 39m
Deal found 9/23$89
Sat 10/34:15 pm -
Nonstop1h 38m
Sat 10/106:13 pm -
Nonstop1h 39m
Deal found 9/18$94
Sun 10/46:35 am -
Nonstop1h 38m
Thu 10/89:28 pm -
Nonstop1h 39m
Deal found 9/18$103
Sat 10/248:05 am -
Nonstop1h 38m
Fri 10/309:41 pm -
Nonstop1h 39m
Deal found 9/20$105
Thu 11/126:03 pm -
Nonstop1h 40m
Sun 11/159:33 pm -
Nonstop1h 42m
Deal found 9/20$108
Sat 10/34:15 pm -
Nonstop1h 38m
Fri 10/98:33 am -
Nonstop1h 39m
Deal found 9/18$116
Sun 10/46:35 am -
Nonstop1h 38m
Sat 10/106:13 pm -
Nonstop1h 39m
Deal found 9/18$120
Sat 10/34:15 pm -
Nonstop1h 38m
Thu 10/89:28 pm -
Nonstop1h 39m
Deal found 9/18$121
Wed 9/308:00 am -
Nonstop1h 38m
Sat 10/106:13 pm -
Nonstop1h 39m
Deal found 9/18$125

Find flight deals from St Petersburg to Knoxville

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$85
(Cheapflightsfares)

One-way from

$46
(Super.com)

Popular in

November

Cheapest in

August

Average price

$186
Provider with most accurate pricing for Tampa St. Petersburg-Knoxville McGhee Tyson flight deals.
Search Deals
Provider most trusted by Cheapflights users for Tampa St. Petersburg-Knoxville McGhee Tyson flights.
Search Deals
From Tampa St. Petersburg to Knoxville McGhee Tyson
Search Deals
One-way flight from Tampa St. Petersburg to Knoxville McGhee Tyson
Search Deals
Highest demand for flights based on searches. 14% potential increase in price ($29 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($5 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in September 2026
Search Deals

Cheapflights Fare Finder

 
Use the filters below to find and compare flights from Tampa to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

TampaKnoxville

PIE Tampa St. Petersburg - TYS Knoxville McGhee Tyson

PIETYS

Tampa St. Petersburg

Wed 9/30

8:00 am-9:38 am

Nonstop1h 38m

Knoxville McGhee Tyson

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$63

TampaKnoxville

PIE Tampa St. Petersburg - TYS Knoxville McGhee Tyson

PIETYS

Tampa St. Petersburg

Wed 11/4

12:05 pm-1:45 pm

Nonstop1h 40m

Knoxville McGhee Tyson

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$66

TampaKnoxville

PIE Tampa St. Petersburg - TYS Knoxville McGhee Tyson

PIETYS

Tampa St. Petersburg

Sun 10/18

6:30 am-8:08 am

Nonstop1h 38m

Knoxville McGhee Tyson

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$108

TampaKnoxville

PIE Tampa St. Petersburg - TYS Knoxville McGhee Tyson

PIETYS

Tampa St. Petersburg

Thu 11/19

7:22 pm-9:04 pm

Nonstop1h 42m

Knoxville McGhee Tyson

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$109

TampaKnoxville

PIE Tampa St. Petersburg - TYS Knoxville McGhee Tyson

PIETYS

Tampa St. Petersburg

Sat 9/26

4:26 pm-6:05 pm

Nonstop1h 39m

Knoxville McGhee Tyson

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$113

TampaKnoxville

PIE Tampa St. Petersburg - TYS Knoxville McGhee Tyson

PIETYS

Tampa St. Petersburg

Tue 10/6

1:36 pm-3:14 pm

Nonstop1h 38m

Knoxville McGhee Tyson

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$123

TampaKnoxville

PIE Tampa St. Petersburg - TYS Knoxville McGhee Tyson

PIETYS

Tampa St. Petersburg

Thu 10/15

7:00 pm-8:38 pm

Nonstop1h 38m

Knoxville McGhee Tyson

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$133

TampaKnoxville

PIE Tampa St. Petersburg - TYS Knoxville McGhee Tyson

PIETYS

Tampa St. Petersburg

Sat 12/19

5:55 pm-7:35 pm

Nonstop1h 40m

Knoxville McGhee Tyson

Tue 12/22

7:00 am-8:42 am

Nonstop1h 42m

$140

TampaKnoxville

PIE Tampa St. Petersburg - TYS Knoxville McGhee Tyson

PIETYS

Tampa St. Petersburg

Mon 12/14

7:05 pm-8:47 pm

Nonstop1h 42m

Knoxville McGhee Tyson

Wed 12/16

8:25 pm-10:07 pm

Nonstop1h 42m

$141

TampaKnoxville

PIE Tampa St. Petersburg - TYS Knoxville McGhee Tyson

PIETYS

Tampa St. Petersburg

Sun 10/4

6:35 am-8:13 am

Nonstop1h 38m

Knoxville McGhee Tyson

Fri 10/9

8:33 am-10:12 am

Nonstop1h 39m

$142

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/20

Showing 1-10 of 22 resultsSorted by cheapest first
1
2
3

Compare providers for flights from St Petersburg to Knoxville

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from St Petersburg to Knoxville in September.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
CheapflightsfaresPrice Accuracy2 starsTrust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Tampa-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Tampa-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Tampa-Knoxville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Tampa-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Tampa-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from St Petersburg to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from St Petersburg with our price prediction graph.
Estimated round-trip price

Cheapflights Insights

Everything you need to know about your flight from Tampa to Knoxville

How far ahead should I book a flight from Tampa to Knoxville?

To ensure you get the cheapest price possible for a flight from Tampa to Knoxville, you should look to book at least 32 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Tampa to Knoxville?

Currently, August is the cheapest month in which you can book a flight from Tampa to Knoxville (average of $117). Flying from Tampa to Knoxville in November is currently the most expensive (average of $233). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PIE to TYS?

One of the essential ways to save on airfare from Tampa to Knoxville is to remain as flexible as possible. Flights that are in the afternoon tend to be the most expensive. A flight in the evening could potentially save you up to 29% on airfare.

What is the cheapest day to fly from Tampa to Knoxville?

Travelers seeking maximum savings on their Tampa to Knoxville flight should consider departing on Monday evenings when fares are most often at their lowest. Saturday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

How much does it cost to fly round-trip from Tampa to Knoxville?

Airfare is below average for this route at the moment.

Tampa to Knoxville flights typically cost between $133 and $229 in October.
The cheapest round-trip price found within the last 5 days was $85 on Allegiant Air (Oct 4-Oct 15).

Reviews of airlines servicing Knoxville

Read through reviews of airlines operating flights from Tampa to Knoxville, such as Allegiant Air. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Allegiant Air
7.3
Good
678 reviews

Entertainment

5.5

Crew

8.1

Overall

7.3

Boarding

7.7

Comfort

6.9

Food

5.8

Reviews

1 / 20
2.0
Mediocre

Nic,Aug 2026

SRQ - ALB

Worker at gate refused to let me measure my personal item and insisted it needed to be a carryon and to pay 75$. I understand if it’s too big but she wouldn’t even let me go measure it. She eventually let me measure my own luggage after back n forth. It is a few inches too big and she comes over and attempts to grab my suitcase out my hands and I pull it away from her. She then shuts the door of the gate and says to call the police. I then just offer to pay for the carryon and she says ok. Then refuses to use let me use my tap to pay, luckily I had my physical card on me. As soon as I walked out the door I respectfully asked for her name. She began screaming at me and threatening me. This worker was just so hostile I understand if my stuffs too big I will pay the difference I’m not trying to get over on the rules. I was confused because I was allowed to board my destination flight with this item as a personal item. So I was confused by this whole situation from the go. It also caused a massive scene at the airport and I was extremely embarrassed. It genuinely seemed like this worker was out to get me for some reason. I had literally just arrived to the gate as it was already boarding so I hadn’t done anything prior. Super weird situation and it really spooked me.
Allegiant Air
7.3
Good
678 reviews
Allegiant Air
7.3
Good
678 reviews

Entertainment

5.5

Crew

8.1

Overall

7.3

Boarding

7.7

Comfort

6.9

Food

5.8

Reviews

1 / 20
2.0
Mediocre

Nic,Aug 2026

SRQ - ALB

Worker at gate refused to let me measure my personal item and insisted it needed to be a carryon and to pay 75$. I understand if it’s too big but she wouldn’t even let me go measure it. She eventually let me measure my own luggage after back n forth. It is a few inches too big and she comes over and attempts to grab my suitcase out my hands and I pull it away from her. She then shuts the door of the gate and says to call the police. I then just offer to pay for the carryon and she says ok. Then refuses to use let me use my tap to pay, luckily I had my physical card on me. As soon as I walked out the door I respectfully asked for her name. She began screaming at me and threatening me. This worker was just so hostile I understand if my stuffs too big I will pay the difference I’m not trying to get over on the rules. I was confused because I was allowed to board my destination flight with this item as a personal item. So I was confused by this whole situation from the go. It also caused a massive scene at the airport and I was extremely embarrassed. It genuinely seemed like this worker was out to get me for some reason. I had literally just arrived to the gate as it was already boarding so I hadn’t done anything prior. Super weird situation and it really spooked me.

Related info for your journey

  • How popular is this Tampa to Knoxville flight route?

    The Tampa St. Petersburg to Knoxville McGhee Tyson flight path was viewed by 5 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Tampa to Knoxville?

    Departing from Tampa to Knoxville will take you 1h 40m. The distance between Tampa and Knoxville is about 551 mi. Most flights are nonstop.

  • What is the cheapest airline to fly from Tampa to Knoxville round-trip?

    Currently priced at $96, Allegiant Air will fly you from Tampa to Knoxville and back. In addition to Allegiant Air, many other airlines offer competitively priced options for your trip. This flight start at 47% lower than the current average price 3 months from now.

  • What are the cheapest flights from Tampa to Knoxville?

    On average you can expect to pay $149 for a flight from Tampa to Knoxville. The cheapest flight overall is $52 while the most popular route, (Tampa St. Petersburg - Knoxville McGhee Tyson) is currently priced at $114.

  • Can I find deals for flights from St Petersburg to Knoxville that include hotel bookings?

    Yes. In addition to deals on St Petersburg to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St Petersburg to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St Petersburg to Knoxville.

  • Can I find deals for business class flights from St Petersburg to Knoxville?

    Yes. Cheapflights offers flight deals from St Petersburg to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Tampa to Knoxville?

    Currently, August is the cheapest month in which you can book a flight from Tampa to Knoxville (average of $117). Flying from Tampa to Knoxville in November is currently the most expensive (average of $233). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Cherokee
Crossville
Morristown
Bryson City
Murphy

Browse thousands of different options on Cheapflights for your next trip

Top airline flying from St Petersburg to Knoxville

AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$96Average$180FlexibilityNo cancel feeOn-time88%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.
Site
©2026 Cheapflights