$155+ Cheap flights from Guatemala City (GUA) to Panama City (PTY)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/27. Fares are subject to change and may not be available on all flights or dates of travel.
GUA — PTY
Oct 29 — Nov 51
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Guatemala City to Panama City with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Guatemala City La Aurora to Panama City Tocumen Intl are usually found in February or April, booked 33 days in advance, depart on a Friday or Wednesday and return on a Tuesday
Cheap flight deals from Guatemala City to Panama City
Cheapest
Best
Last-minute
One-way
Cheapest flights from Guatemala City to Panama CityExplore the most affordable flight options available from Guatemala City to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 29, 2026.
Explore the most affordable flight options available from Guatemala City to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 29, 2026.
This Avianca deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/282:00 pm -
1 stop10h 20m
Mon 11/25:30 am -
1 stop4h 25m
Deal found 9/29![Avianca logo]()
$262
This Copa Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/16:19 am -
1 stop3h 50m
Thu 11/510:25 am -
Nonstop2h 25m
Deal found 9/24![Copa Airlines logo]()
$282
This Copa Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:24 am -
1 stop5h 04m
Thu 11/57:25 am -
Nonstop2h 21m
Deal found 9/29![Copa Airlines logo]()
$291
This Avianca deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/249:30 am -
1 stop14h 05m
Thu 10/292:30 am -
1 stop15h 55m
Deal found 9/29![Avianca logo]()
$299
This Avianca deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/288:15 pm -
1 stop4h 40m
Sat 10/314:10 pm -
1 stop9h 45m
Deal found 9/28![Avianca logo]()
$301
This Copa Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/287:17 am -
Nonstop2h 30m
Wed 11/410:34 am -
1 stop12h 02m
Deal found 9/29![Copa Airlines logo]()
$302
This Copa Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/284:14 am -
Nonstop2h 30m
Mon 11/210:25 am -
Nonstop2h 25m
Deal found 9/28![Copa Airlines logo]()
$306
This Avianca deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/157:00 am -
1 stop6h 55m
Tue 10/276:10 pm -
1 stop7h 45m
Deal found 9/29![Avianca logo]()
$308
This Copa Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:24 am -
1 stop12h 56m
Sun 11/18:15 am -
Nonstop2h 24m
Deal found 9/28![Copa Airlines logo]()
$314
Best flights from Guatemala City to Panama CityDiscover carefully curated flight deals from Guatemala City to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 29, 2026.
Discover carefully curated flight deals from Guatemala City to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 29, 2026.
This Copa Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/16:19 am -
1 stop3h 50m
Thu 11/510:25 am -
Nonstop2h 25m
Deal found 9/24![Copa Airlines logo]()
$282
This Copa Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/287:17 am -
Nonstop2h 30m
Wed 11/46:30 pm -
Nonstop2h 21m
Deal found 9/29![Copa Airlines logo]()
$317
This Copa Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3010:43 am -
Nonstop2h 30m
Wed 11/46:30 pm -
Nonstop2h 21m
Deal found 9/29![Copa Airlines logo]()
$317
This Copa Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/104:16 am -
Nonstop2h 28m
Sat 11/147:25 am -
Nonstop2h 21m
Deal found 9/28![Copa Airlines logo]()
$319
This Copa Airlines deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:24 am -
1 stop3h 46m
Wed 10/287:24 am -
Nonstop2h 22m
Deal found 9/26![Copa Airlines logo]()
$343
This Copa Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/167:06 am -
Nonstop2h 30m
Thu 10/227:24 am -
Nonstop2h 22m
Deal found 9/24![Copa Airlines logo]()
$356
This Copa Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/184:18 am -
Nonstop2h 26m
Sat 12/267:25 am -
Nonstop2h 21m
Deal found 9/28![Copa Airlines logo]()
$356
This Copa Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/224:25 pm -
Nonstop2h 30m
Sun 10/258:15 am -
Nonstop2h 22m
Deal found 9/24![Copa Airlines logo]()
$356
Last-minute flights from Guatemala City to Panama CityDiscover last-minute flight deals from Guatemala City to Panama City. Data last updated September 29, 2026 and is based on user searches.
Discover last-minute flight deals from Guatemala City to Panama City. Data last updated September 29, 2026 and is based on user searches.
This Avianca deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/157:00 am -
1 stop6h 55m
Tue 10/276:10 pm -
1 stop7h 45m
Deal found 9/29![Avianca logo]()
$308
This Avianca deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/249:30 am -
1 stop14h 05m
Thu 10/292:30 am -
1 stop15h 55m
Deal found 9/29![Avianca logo]()
$299
This Avianca deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/282:00 pm -
1 stop10h 20m
Mon 11/25:30 am -
1 stop4h 25m
Deal found 9/29![Avianca logo]()
$262
This Copa Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/287:17 am -
Nonstop2h 30m
Wed 11/410:34 am -
1 stop12h 02m
Deal found 9/29![Copa Airlines logo]()
$302
This Copa Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/284:14 am -
Nonstop2h 30m
Mon 11/210:25 am -
Nonstop2h 25m
Deal found 9/28![Copa Airlines logo]()
$306
This Copa Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/291:09 pm -
Nonstop2h 30m
Thu 11/510:25 am -
Nonstop2h 25m
Deal found 9/29![Copa Airlines logo]()
$282
This Copa Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:24 am -
1 stop12h 56m
Sun 11/18:15 am -
Nonstop2h 24m
Deal found 9/28![Copa Airlines logo]()
$314
This Avianca deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/302:00 pm -
1 stop10h 20m
Tue 12/16:10 pm -
1 stop7h 45m
Deal found 9/29![Avianca logo]()
$315
One-way flights from Guatemala City to Panama CitySearch for one-way flight options from Guatemala City to Panama City. Find affordable one-way fares based on user searches. Data last updated September 29, 2026.
Search for one-way flight options from Guatemala City to Panama City. Find affordable one-way fares based on user searches. Data last updated September 29, 2026.
This Copa Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/274:14 am -
Nonstop2h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/24![Copa Airlines logo]()
$155
This Copa Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/316:24 am -
1 stop5h 04m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/28![Copa Airlines logo]()
$164
This FlightHub deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/181:55 pm -
1 stop9h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/25![Avianca logo]()
$311
This FlightHub deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/172:00 pm -
1 stop10h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/25![Avianca logo]()
$312
This FlightHub deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/25:25 am -
1 stop4h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/24![Avianca logo]()
$313
This FlightHub deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/31:55 pm -
1 stop9h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/25![Avianca logo]()
$316
This Avianca deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/48:15 pm -
1 stop4h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/26![Avianca logo]()
$318
This Avianca deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/108:15 pm -
1 stop4h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/28![Avianca logo]()
$319
Find flight deals from Guatemala City to Panama City
Discover tips and strategies to find the most affordable flight options for your journey from Guatemala City (GUA) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 29, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $262 (Avianca) |
One-way from | $155 (Copa Airlines) |
Popular in | July |
Cheapest in | February |
Average price | $336 |
Good round-trip deal | $394 or less |
Good one-way deal | $239 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Guatemala City to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 29, 2026.
Use the filters below to find and compare flights from Guatemala City to Panama City that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Guatemala CityPanama City
GUA Guatemala City La Aurora - PTY Panama City Tocumen Intl
GUAPTY
Guatemala City La Aurora
Wed 11/4
4:17 pm-7:51 pm
Nonstop2h 34m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$155
Guatemala CityPanama City
GUA Guatemala City La Aurora - PTY Panama City Tocumen Intl
GUAPTY
Guatemala City La Aurora
Tue 10/27
6:24 am-11:09 am
1 stop3h 45m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$155
Quickest round-trip
Guatemala CityPanama City
GUA Guatemala City La Aurora - PTY Panama City Tocumen Intl
GUAPTY
Guatemala City La Aurora
Fri 10/30
2:19 am-5:49 am
Nonstop2h 30m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$155
Guatemala CityPanama City
GUA Guatemala City La Aurora - PTY Panama City Tocumen Intl
GUAPTY
Guatemala City La Aurora
Thu 10/29
4:14 am-7:44 am
Nonstop2h 30m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$155
Guatemala CityPanama City
GUA Guatemala City La Aurora - PTY Panama City Tocumen Intl
GUAPTY
Guatemala City La Aurora
Sun 11/1
6:19 am-11:09 am
1 stop3h 50m
Panama City Tocumen Intl
Thu 11/5
10:25 am-11:50 am
Nonstop2h 25m
$282
Guatemala CityPanama City
GUA Guatemala City La Aurora - PTY Panama City Tocumen Intl
GUAPTY
Guatemala City La Aurora
Wed 10/28
7:17 am-10:47 am
Nonstop2h 30m
Panama City Tocumen Intl
Wed 11/4
6:30 pm-7:51 pm
Nonstop2h 21m
$317
Guatemala CityPanama City
GUA Guatemala City La Aurora - PTY Panama City Tocumen Intl
GUAPTY
Guatemala City La Aurora
Fri 10/30
10:43 am-2:13 pm
Nonstop2h 30m
Panama City Tocumen Intl
Wed 11/4
6:30 pm-7:51 pm
Nonstop2h 21m
$317
Guatemala CityPanama City
GUA Guatemala City La Aurora - PTY Panama City Tocumen Intl
GUAPTY
Guatemala City La Aurora
Tue 11/10
4:16 am-7:44 am
Nonstop2h 28m
Panama City Tocumen Intl
Sat 11/14
7:25 am-8:46 am
Nonstop2h 21m
$319
Guatemala CityPanama City
GUA Guatemala City La Aurora - PTY Panama City Tocumen Intl
GUAPTY
Guatemala City La Aurora
Sat 10/24
6:24 am-11:10 am
1 stop3h 46m
Panama City Tocumen Intl
Wed 10/28
7:24 am-8:46 am
Nonstop2h 22m
$343
Guatemala CityPanama City
GUA Guatemala City La Aurora - PTY Panama City Tocumen Intl
GUAPTY
Guatemala City La Aurora
Fri 10/16
7:06 am-10:36 am
Nonstop2h 30m
Panama City Tocumen Intl
Thu 10/22
7:24 am-8:46 am
Nonstop2h 22m
$356
Showing 1-10 of 12 resultsSorted by cheapest first
Compare providers for flights from Guatemala City to Panama City
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Guatemala City to Panama City in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Guatemala City-Panama City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Guatemala City-Panama City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Guatemala City-Panama City flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Guatemala City-Panama City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Guatemala City-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Guatemala City to Panama City
Have a flexible travel schedule? Discover the best time to fly to Panama City from Guatemala City with our price prediction graph.
GUA-PTY
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Guatemala City to Panama City
Prices
Airlines
Delays
How far ahead should I book a flight from Guatemala City to Panama City?
The best time to book flights from Guatemala City to Panama City is 32 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
What is the cheapest month to book a flight from Guatemala City to Panama City?
Currently, February is the cheapest month in which you can book a flight from Guatemala City to Panama City (average of $280). Flying from Guatemala City to Panama City in July is currently the most expensive (average of $354). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from GUA to PTY?
Find hourly flight availability from Guatemala City to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 29, 2026.
One of the essential ways to save on airfare from Guatemala City to Panama City is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the evening could potentially save you up to 63% on airfare.
What is the cheapest day to fly from Guatemala City to Panama City?
Use this chart to determine the cheapest time to fly round-trip from Guatemala City to Panama City. Price data was last updated on September 26, 2026.
Travelers seeking maximum savings on their Guatemala City to Panama City flight should consider departing on Thursday evenings when fares are most often at their lowest. Monday at noon flights should be avoided if possible as fares are typically the most expensive at this time.
How often are flights from Guatemala City to Panama City delayed?
About 3% of weekly flights between Guatemala City and Panama City have experienced delays in the past year, with the average delay time being 124 minutes.
What is the most punctual flight time for Guatemala City to Panama City flights?
Historically, flights departing at night are less likely to be delayed, whereas flights leaving in the evening tend to experience delays more often.
What day of the week experiences the fewest flight delays on this route?
Monday tends to have the lowest number of delays on this route, whereas Sunday has historically faced a higher average of delays compared to other days of the week.
Which airline has the best punctuality record on Guatemala City to Panama City flights?
Over the last year, Copa Airlines have had the lowest number of delays on this route, with just 3% of flights being delayed.
The best insider tips for Guatemala City to Panama City flights
AI-powered summary based on content written by travel experts. AI can make mistakes.
Cheapflights partnered with top experts to bring you the best recommendations for your Guatemala City to Panama City trip
Our travel experts
Reviews of airlines servicing Panama City
Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated September 29, 2026.
See what other customers who have flown with Copa Airlines and Avianca from Guatemala City to Panama City have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
7.8
Comfort
7.4
Food
6.9
Crew
8.1
Entertainment
6.9
Overall
7.6
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Boarding
7.8
Comfort
7.4
Food
6.9
Crew
8.1
Entertainment
6.9
Overall
7.6
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Boarding
7.8
Comfort
7.4
Food
6.9
Crew
8.1
Entertainment
6.9
Overall
7.6
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Related info for your journey
Find useful and relevant information for your journey from Guatemala City to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Complete your trip
Flights by cabin class
Other flight options
Other flights from Guatemala City
Panama City flight routes
Popular flights
Complete your trip
Complete your trip to Panama City by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Guatemala City to Panama City by cabin class
Find flights from Guatemala City to Panama City, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Guatemala City and Panama City flights
Browse other Guatemala City and Panama City flight options. Last updated on September 29, 2026.
Other flights from Guatemala City
Browse through other flights departing from Guatemala City. Flights are based on user searches made on Cheapflights and were last updated on September 29, 2026.
Other flights to Panama City
Explore flights to Panama City departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 29, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Guatemala City to Panama City
Discover the top 2 airlines that operate flights from Guatemala City to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 29, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$161 | Average$307 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$199 | Average$334 | FlexibilityNo cancel fee | On-time70% |