$135+ Cheap flights from Knoxville (TYS) to Panama City Beach, FL
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/24. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — PNS
Jun 6 — Jun 131
Round-trip
1 adult, Economy
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Find cheap flights from Knoxville to Panama City Beach with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Knoxville to Panama City Beach
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Best
Last-minute
One-way
Cheapest flights from Knoxville to Panama City BeachExplore the most affordable flight options available from Knoxville to Panama City Beach. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 7, 2026.
Explore the most affordable flight options available from Knoxville to Panama City Beach. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 7, 2026.
This Delta deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/2311:55 am
TYS
- ECP
1 stop5h 28m
Delta
Tue 6/307:41 am
ECP
- TYS
1 stop4h 38m
Delta
Deal found 5/4![Delta logo]()
$249
This Southwest deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/238:10 am
TYS
- ECP
2 stops12h 30m
Southwest
Tue 6/307:00 am
ECP
- TYS
1 stop6h 05m
Southwest
Deal found 5/4![Southwest logo]()
$260
This Delta deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/275:59 pm
TYS
- ECP
1 stop6h 02m
Delta
Fri 5/299:19 am
ECP
- TYS
1 stop2h 51m
Delta
Deal found 5/4![Delta logo]()
$274
This Delta deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/110:25 am
TYS
- ECP
1 stop3h 25m
Delta
Mon 6/89:19 am
ECP
- TYS
1 stop3h 00m
Delta
Deal found 5/4![Delta logo]()
$277
This Southwest deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/62:05 pm
TYS
- ECP
1 stop7h 55m
Southwest
Tue 8/1111:30 am
ECP
- TYS
2 stops7h 20m
Southwest
Deal found 5/4![Southwest logo]()
$279
This American Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/37:59 pm
TYS
- ECP
1 stop4h 41m
American Airlines
Fri 6/126:45 pm
ECP
- TYS
1 stop4h 02m
American Airlines
Deal found 5/6![American Airlines logo]()
$284
This Southwest deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/178:10 am
TYS
- ECP
2 stops12h 30m
Southwest
Tue 6/237:40 am
ECP
- TYS
2 stops8h 20m
Southwest
Deal found 5/6![Southwest logo]()
$285
This Delta deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/87:35 am
TYS
- ECP
1 stop4h 19m
Delta
Fri 6/126:45 pm
ECP
- TYS
1 stop4h 09m
Delta
Deal found 5/5![Delta logo]()
$288
This Southwest deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/268:00 am
TYS
- ECP
2 stops11h 10m
Southwest
Sun 8/307:00 am
ECP
- TYS
1 stop6h 00m
Southwest
Deal found 5/6![Southwest logo]()
$289
Best flights from Knoxville to Panama City BeachDiscover carefully curated flight deals from Knoxville to Panama City Beach that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 7, 2026.
Discover carefully curated flight deals from Knoxville to Panama City Beach that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 7, 2026.
This Southwest deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/62:05 pm
TYS
- ECP
1 stop7h 55m
Southwest
Tue 8/1111:30 am
ECP
- TYS
2 stops7h 20m
Southwest
Deal found 5/4![Southwest logo]()
$279
This Delta deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/305:40 am
TYS
- ECP
1 stop3h 50m
Delta
Fri 6/56:00 am
ECP
- TYS
1 stop4h 09m
Delta
Deal found 5/6![Delta logo]()
$288
This Southwest deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/267:00 am
TYS
- ECP
1 stop3h 40m
Southwest
Sun 8/307:00 am
ECP
- TYS
1 stop6h 00m
Southwest
Deal found 5/6![Southwest logo]()
$284
This Delta deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/65:40 am
TYS
- ECP
1 stop3h 34m
Delta
Fri 7/107:50 am
ECP
- TYS
1 stop4h 26m
Delta
Deal found 5/6![Delta logo]()
$309
This Southwest deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/12:45 pm
TYS
- ECP
1 stop8h 20m
Southwest
Wed 7/87:40 am
ECP
- TYS
2 stops8h 20m
Southwest
Deal found 5/4![Southwest logo]()
$285
This Southwest deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/186:55 pm
TYS
- ECP
1 stop4h 00m
Southwest
Thu 7/2310:15 am
ECP
- TYS
2 stops9h 55m
Southwest
Deal found 5/3![Southwest logo]()
$304
This Southwest deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/237:45 am
TYS
- ECP
2 stops9h 00m
Southwest
Sat 5/3012:40 pm
ECP
- TYS
1 stop4h 50m
Southwest
Deal found 5/2![Southwest logo]()
$323
This Southwest deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2812:30 pm
TYS
- ECP
2 stops7h 30m
Southwest
Sat 10/35:55 am
ECP
- TYS
2 stops10h 45m
Southwest
Deal found 5/7![Southwest logo]()
$327
This Southwest deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/66:40 am
TYS
- ECP
2 stops8h 35m
Southwest
Fri 7/101:25 pm
ECP
- TYS
2 stops6h 45m
Southwest
Deal found 5/6![Southwest logo]()
$348
Last-minute flights from Knoxville to Panama City BeachDiscover last-minute flight deals from Knoxville to Panama City Beach. Data last updated May 7, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to Panama City Beach. Data last updated May 7, 2026 and is based on user searches.
This Southwest deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/247:30 am
TYS
- ECP
2 stops10h 55m
Southwest
Wed 5/2712:05 pm
ECP
- TYS
2 stops7h 45m
Southwest
Deal found 5/3![Southwest logo]()
$290
This Delta deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/275:59 pm
TYS
- ECP
1 stop6h 02m
Delta
Fri 5/299:19 am
ECP
- TYS
1 stop2h 51m
Delta
Deal found 5/4![Delta logo]()
$274
This American Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/37:59 pm
TYS
- ECP
1 stop4h 41m
American Airlines
Fri 6/126:45 pm
ECP
- TYS
1 stop4h 02m
American Airlines
Deal found 5/6![American Airlines logo]()
$284
This Delta deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/47:33 pm
TYS
- ECP
1 stop4h 55m
Delta
Mon 6/87:41 am
ECP
- TYS
1 stop4h 38m
Delta
Deal found 5/6![Delta logo]()
$277
This Delta deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/87:35 am
TYS
- ECP
1 stop4h 19m
Delta
Fri 6/126:45 pm
ECP
- TYS
1 stop4h 09m
Delta
Deal found 5/5![Delta logo]()
$288
This Southwest deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/178:10 am
TYS
- ECP
2 stops12h 30m
Southwest
Tue 6/237:40 am
ECP
- TYS
2 stops8h 20m
Southwest
Deal found 5/6![Southwest logo]()
$285
This Delta deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/2311:55 am
TYS
- ECP
1 stop5h 28m
Delta
Tue 6/307:41 am
ECP
- TYS
1 stop4h 38m
Delta
Deal found 5/4![Delta logo]()
$249
This Southwest deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/238:10 am
TYS
- ECP
2 stops12h 30m
Southwest
Tue 6/307:00 am
ECP
- TYS
1 stop6h 05m
Southwest
Deal found 5/4![Southwest logo]()
$260
One-way flights from Knoxville to Panama City BeachSearch for one-way flight options from Knoxville to Panama City Beach. Find affordable one-way fares based on user searches. Data last updated May 7, 2026.
Search for one-way flight options from Knoxville to Panama City Beach. Find affordable one-way fares based on user searches. Data last updated May 7, 2026.
This Delta deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/245:40 am
TYS
- ECP
1 stop3h 34m
Delta
Deal found 5/5![Delta logo]()
$135
This Delta deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/253:30 pm
TYS
- ECP
1 stop3h 26m
Delta
Deal found 5/4![Delta logo]()
$139
This Southwest deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/72:45 pm
TYS
- ECP
1 stop8h 20m
Southwest
Deal found 5/6![Southwest logo]()
$140
This Southwest deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/248:10 am
TYS
- ECP
2 stops12h 30m
Southwest
Deal found 5/5![Southwest logo]()
$146
This Delta deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/55:40 am
TYS
- ECP
1 stop3h 34m
Delta
Deal found 5/6![Delta logo]()
$150
This Southwest deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/412:35 pm
TYS
- ECP
2 stops8h 35m
Southwest
Deal found 5/7![Southwest logo]()
$165
This Southwest deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/68:55 am
TYS
- ECP
2 stops12h 30m
Southwest
Deal found 5/4![Southwest logo]()
$184
This Southwest deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/258:05 am
TYS
- ECP
2 stops12h 45m
Southwest
Deal found 5/4![Southwest logo]()
$200
This Delta deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/235:40 am
TYS
- ECP
1 stop3h 50m
Delta
Deal found 5/6![Delta logo]()
$219
This Southwest deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/237:45 am
TYS
- ECP
2 stops9h 00m
Southwest
Deal found 5/6![Southwest logo]()
$224
This Southwest deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/267:05 am
TYS
- ECP
2 stops10h 15m
Southwest
Deal found 5/7![Southwest logo]()
$230
Find flight deals from Knoxville to Panama City Beach
Keep the following information in mind while searching for Knoxville to Panama City Beach flight deals. Data was last updated May 7, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $249 (Delta) |
One-way from | $135 (Delta) |
Popular in | June |
Cheapest in | August |
Average price | $366 |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to Panama City Beach that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 7, 2026.
Use the filters below to find and compare flights from Knoxville to Panama City Beach that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvillePanama City
TYS - ECP
TYSECP
Knoxville McGhee Tyson
Thu 8/6
2:05 pm-9:00 pm
1 stop7h 55m
Panama City NW Florida Beaches
Tue 8/11
11:30 am-7:50 pm
2 stops7h 20m
$279
KnoxvillePanama City
TYS - ECP
TYSECP
Knoxville McGhee Tyson
Wed 8/26
7:00 am-9:40 am
1 stop3h 40m
Panama City NW Florida Beaches
Sun 8/30
7:00 am-2:00 pm
1 stop6h 00m
$284
KnoxvillePanama City
TYS - ECP
TYSECP
Knoxville McGhee Tyson
Wed 7/1
2:45 pm-10:05 pm
1 stop8h 20m
Panama City NW Florida Beaches
Wed 7/8
7:40 am-5:00 pm
2 stops8h 20m
$285
Quickest round-trip
KnoxvillePanama City
TYS - ECP
TYSECP
Knoxville McGhee Tyson
Sat 5/30
5:40 am-8:30 am
1 stop3h 50m
Panama City NW Florida Beaches
Fri 6/5
6:00 am-11:09 am
1 stop4h 09m
$288
KnoxvillePanama City
TYS - ECP
TYSECP
Knoxville McGhee Tyson
Sat 7/18
6:55 pm-9:55 pm
1 stop4h 00m
Panama City NW Florida Beaches
Thu 7/23
10:15 am-9:10 pm
2 stops9h 55m
$304
KnoxvillePanama City
TYS - ECP
TYSECP
Knoxville McGhee Tyson
Mon 7/6
5:40 am-8:14 am
1 stop3h 34m
Panama City NW Florida Beaches
Fri 7/10
7:50 am-1:16 pm
1 stop4h 26m
$309
KnoxvillePanama City
TYS - ECP
TYSECP
Knoxville McGhee Tyson
Sat 5/23
7:45 am-3:45 pm
2 stops9h 00m
Panama City NW Florida Beaches
Sat 5/30
12:40 pm-6:30 pm
1 stop4h 50m
$323
KnoxvillePanama City
TYS - ECP
TYSECP
Knoxville McGhee Tyson
Mon 9/28
12:30 pm-7:00 pm
2 stops7h 30m
Panama City NW Florida Beaches
Sat 10/3
5:55 am-5:40 pm
2 stops10h 45m
$327
KnoxvillePanama City
TYS - ECP
TYSECP
Knoxville McGhee Tyson
Mon 7/6
6:40 am-2:15 pm
2 stops8h 35m
Panama City NW Florida Beaches
Fri 7/10
1:25 pm-9:10 pm
2 stops6h 45m
$348
Cheapest one-way
KnoxvillePanama City
TYS - ECP
TYSECP
Knoxville McGhee Tyson
Wed 6/24
5:40 am-8:14 am
1 stop3h 34m
$135
Showing 1-10 of 20 resultsSorted by cheapest first
Best time to book a flight from Knoxville to Panama City Beach
Have a flexible travel schedule? Discover the best time to fly to Panama City Beach from Knoxville with our price prediction graph.
TYS-ECP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Knoxville to Panama City Beach
TYS-PA9
TYS-ECP
What is the cheapest time of day to fly from TYS to PA9?
Find hourly flight availability from Knoxville to Panama City Beach. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 7, 2026.
One of the essential ways to save on airfare from Knoxville to Panama City Beach is to remain as flexible as possible. Flights that are in the evening tend to be the most expensive. A flight in the morning could potentially save you up to 20% on airfare.
How much does it cost to fly round-trip from Knoxville to Panama City Beach?
Reviews of airlines servicing Panama City Beach
Get insights into the airlines that provide service to Panama City Beach. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City Beach. Reviews last updated May 7, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andAmerican Airlines from Knoxville to Panama City Beach to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Entertainment
7.5
Overall
7.9
Comfort
8.0
Crew
8.6
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Entertainment
7.5
Overall
7.9
Comfort
8.0
Crew
8.6
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Entertainment
7.5
Overall
7.9
Comfort
8.0
Crew
8.6
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Entertainment
7.5
Overall
7.9
Comfort
8.0
Crew
8.6
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Knoxville to Panama City Beach. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Knoxville and Panama City Beach flights
Browse other Knoxville and Panama City Beach flight options. Last updated on May 7, 2026.
Other flights from Knoxville
Browse through other flights departing from Knoxville. Flights are based on user searches made on Cheapflights and were last updated on May 7, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Knoxville to Panama City Beach flights
Consider these flights traveling from Knoxville to Panama City Beach.
Top 4 airlines flying from Knoxville to Panama City Beach
Discover the top 4 airlines that operate flights from Knoxville to Panama City Beach. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 7, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$67 | Average$133 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$124 | Average$384 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$228 | Average$422 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$256 | Average$333 | FlexibilityNo cancel fee | On-time63% |