$135+ Cheap flights from Knoxville (TYS) to Panama City Beach, FL
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/15. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — PNS
Sep 4 — Sep 111
Round-trip
1 adult, Economy
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Find cheap flights from Knoxville to Panama City Beach with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Knoxville to Panama City Beach
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Best
Last-minute
One-way
Cheapest flights from Knoxville to Panama City BeachExplore the most affordable flight options available from Knoxville to Panama City Beach. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 5, 2026.
Explore the most affordable flight options available from Knoxville to Panama City Beach. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 5, 2026.
This Southwest deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/112:05 pm -
1 stop8h 00m
Mon 9/146:00 am -
1 stop6h 25m
Deal found 8/3![Southwest logo]()
$256
This Delta deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/95:40 am -
1 stop3h 36m
Tue 9/151:46 pm -
1 stop5h 29m
Deal found 8/3![Delta logo]()
$258
This Southwest deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/91:55 pm -
2 stops7h 40m
Tue 9/157:45 am -
1 stop3h 20m
Deal found 8/3![Southwest logo]()
$263
This Delta deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/177:25 pm -
1 stop5h 00m
Wed 9/235:30 pm -
1 stop5h 25m
Deal found 7/31![Delta logo]()
$269
This Southwest deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/261:55 pm -
2 stops7h 35m
Mon 8/317:05 am -
1 stop4h 15m
Deal found 8/3![Southwest logo]()
$274
This Delta deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/95:40 am -
1 stop3h 36m
Sun 9/136:00 am -
1 stop4h 23m
Deal found 8/1![Delta logo]()
$278
This Delta deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/95:40 am -
1 stop3h 34m
Thu 10/156:20 pm -
1 stop4h 39m
Deal found 8/4![Delta logo]()
$279
This Southwest deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/272:05 pm -
1 stop7h 55m
Mon 8/317:05 am -
2 stops9h 05m
Deal found 8/4![Southwest logo]()
$284
This Delta deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/116:23 pm -
1 stop3h 43m
Thu 10/156:20 pm -
1 stop4h 39m
Deal found 8/4![Delta logo]()
$289
This Southwest deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/287:10 am -
2 stops14h 50m
Sat 8/297:45 am -
1 stop3h 10m
Deal found 8/4![Southwest logo]()
$290
Best flights from Knoxville to Panama City BeachDiscover carefully curated flight deals from Knoxville to Panama City Beach that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 5, 2026.
Discover carefully curated flight deals from Knoxville to Panama City Beach that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 5, 2026.
This Delta deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/95:40 am -
1 stop3h 36m
Mon 9/146:20 pm -
1 stop4h 35m
Deal found 8/3![Delta logo]()
$258
This Southwest deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/261:55 pm -
2 stops7h 35m
Mon 8/317:05 am -
1 stop4h 15m
Deal found 8/3![Southwest logo]()
$274
This Delta deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/264:38 pm -
1 stop2h 57m
Mon 8/317:35 am -
1 stop4h 59m
Deal found 8/3![Delta logo]()
$269
This Southwest deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/252:05 pm -
1 stop8h 00m
Mon 9/287:05 am -
1 stop4h 15m
Deal found 8/1![Southwest logo]()
$279
This Delta deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/175:40 am -
1 stop3h 36m
Mon 9/216:00 am -
1 stop4h 18m
Deal found 8/4![Delta logo]()
$269
This Delta deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/175:40 am -
1 stop3h 34m
Sat 10/245:40 pm -
1 stop3h 42m
Deal found 8/2![Delta logo]()
$269
This Delta deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/175:40 am -
1 stop3h 36m
Wed 9/236:00 am -
1 stop4h 18m
Deal found 8/1![Delta logo]()
$269
This Southwest deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/197:00 am -
2 stops11h 00m
Mon 8/317:05 am -
2 stops9h 05m
Deal found 8/3![Southwest logo]()
$369
This Delta deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/165:40 am -
1 stop3h 34m
Tue 10/207:07 am -
1 stop5h 33m
Deal found 8/1![Delta logo]()
$279
This Delta deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/286:12 pm -
1 stop2h 56m
Fri 9/41:53 pm -
1 stop5h 10m
Deal found 7/31![Delta logo]()
$299
This Southwest deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/117:10 am -
2 stops9h 35m
Mon 9/145:10 am -
2 stops7h 15m
Deal found 8/3![Southwest logo]()
$429
This Delta deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/135:40 am -
1 stop3h 36m
Sun 9/136:20 pm -
1 stop4h 35m
Deal found 8/4![Delta logo]()
$397
Last-minute flights from Knoxville to Panama City BeachDiscover last-minute flight deals from Knoxville to Panama City Beach. Data last updated August 5, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to Panama City Beach. Data last updated August 5, 2026 and is based on user searches.
This Southwest deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/261:55 pm -
2 stops7h 35m
Mon 8/317:05 am -
1 stop4h 15m
Deal found 8/3![Southwest logo]()
$274
This Southwest deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/272:05 pm -
1 stop7h 55m
Mon 8/317:05 am -
2 stops9h 05m
Deal found 8/4![Southwest logo]()
$284
This Delta deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/277:41 pm -
1 stop4h 49m
Sun 8/3011:31 am -
1 stop2h 59m
Deal found 7/31![Delta logo]()
$289
This Delta deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/95:40 am -
1 stop3h 36m
Tue 9/151:46 pm -
1 stop5h 29m
Deal found 8/3![Delta logo]()
$258
This Southwest deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/91:55 pm -
2 stops7h 40m
Tue 9/157:45 am -
1 stop3h 20m
Deal found 8/3![Southwest logo]()
$263
This Delta deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/95:40 am -
1 stop3h 36m
Sun 9/136:00 am -
1 stop4h 23m
Deal found 8/1![Delta logo]()
$278
This Delta deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/115:40 am -
1 stop3h 36m
Wed 9/166:00 am -
1 stop4h 18m
Deal found 7/30![Delta logo]()
$245
This Southwest deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/112:05 pm -
1 stop8h 00m
Mon 9/146:00 am -
1 stop6h 25m
Deal found 8/3![Southwest logo]()
$256
This Delta deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/177:25 pm -
1 stop5h 00m
Wed 9/235:30 pm -
1 stop5h 25m
Deal found 7/31![Delta logo]()
$269
This Southwest deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/252:05 pm -
1 stop8h 00m
Mon 9/287:05 am -
1 stop4h 15m
Deal found 8/1![Southwest logo]()
$279
One-way flights from Knoxville to Panama City BeachSearch for one-way flight options from Knoxville to Panama City Beach. Find affordable one-way fares based on user searches. Data last updated August 5, 2026.
Search for one-way flight options from Knoxville to Panama City Beach. Find affordable one-way fares based on user searches. Data last updated August 5, 2026.
This Delta deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/155:40 am -
1 stop5h 54m
Deal found 7/31![Delta logo]()
$135
This Southwest deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/158:05 am -
2 stops11h 10m
Deal found 7/31![Southwest logo]()
$140
This Delta deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1612:06 pm -
1 stop4h 26m
Deal found 8/3![Delta logo]()
$145
This Delta deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/226:09 pm -
1 stop6h 15m
Deal found 8/3![Delta logo]()
$155
This Southwest deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/17:05 am -
2 stops11h 15m
Deal found 8/4![Southwest logo]()
$189
This Delta deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/105:40 am -
1 stop3h 36m
Deal found 8/1![Delta logo]()
$194
This Delta deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/175:40 am -
1 stop6h 02m
Deal found 8/3![Delta logo]()
$224
This Southwest deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/207:10 am -
2 stops6h 40m
Deal found 8/4![Southwest logo]()
$229
This Southwest deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/107:10 am -
2 stops14h 55m
Deal found 8/1![Southwest logo]()
$240
This Southwest deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/167:15 am -
2 stops9h 10m
Deal found 7/31![Southwest logo]()
$259
This Southwest deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/177:10 am -
2 stops6h 40m
Deal found 8/3![Southwest logo]()
$269
This Delta deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/166:12 pm -
1 stop2h 56m
Deal found 8/4![Delta logo]()
$319
Find flight deals from Knoxville to Panama City Beach
Keep the following information in mind while searching for Knoxville to Panama City Beach flight deals. Data was last updated August 5, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $245 (Delta) |
One-way from | $135 (Delta) |
Popular in | December |
Cheapest in | May |
Average price | $346 |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to Panama City Beach that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 5, 2026.
Use the filters below to find and compare flights from Knoxville to Panama City Beach that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvillePanama City
TYS - ECP
TYSECP
Knoxville McGhee Tyson
Wed 9/9
5:40 am-8:16 am
1 stop3h 36m
Panama City NW Florida Beaches
Mon 9/14
6:20 pm-11:55 pm
1 stop4h 35m
$258
KnoxvillePanama City
TYS - ECP
TYSECP
Knoxville McGhee Tyson
Wed 8/26
4:38 pm-6:35 pm
1 stop2h 57m
Panama City NW Florida Beaches
Mon 8/31
7:35 am-1:34 pm
1 stop4h 59m
$269
KnoxvillePanama City
TYS - ECP
TYSECP
Knoxville McGhee Tyson
Thu 9/17
5:40 am-8:16 am
1 stop3h 36m
Panama City NW Florida Beaches
Mon 9/21
6:00 am-11:18 am
1 stop4h 18m
$269
Quickest round-trip
KnoxvillePanama City
TYS - ECP
TYSECP
Knoxville McGhee Tyson
Sat 10/17
5:40 am-8:14 am
1 stop3h 34m
Panama City NW Florida Beaches
Sat 10/24
5:40 pm-10:22 pm
1 stop3h 42m
$269
KnoxvillePanama City
TYS - ECP
TYSECP
Knoxville McGhee Tyson
Thu 9/17
5:40 am-8:16 am
1 stop3h 36m
Panama City NW Florida Beaches
Wed 9/23
6:00 am-11:18 am
1 stop4h 18m
$269
KnoxvillePanama City
TYS - ECP
TYSECP
Knoxville McGhee Tyson
Wed 8/26
1:55 pm-8:30 pm
2 stops7h 35m
Panama City NW Florida Beaches
Mon 8/31
7:05 am-12:20 pm
1 stop4h 15m
$274
KnoxvillePanama City
TYS - ECP
TYSECP
Knoxville McGhee Tyson
Fri 9/25
2:05 pm-9:05 pm
1 stop8h 00m
Panama City NW Florida Beaches
Mon 9/28
7:05 am-12:20 pm
1 stop4h 15m
$279
KnoxvillePanama City
TYS - ECP
TYSECP
Knoxville McGhee Tyson
Fri 10/16
5:40 am-8:14 am
1 stop3h 34m
Panama City NW Florida Beaches
Tue 10/20
7:07 am-1:40 pm
1 stop5h 33m
$279
KnoxvillePanama City
TYS - ECP
TYSECP
Knoxville McGhee Tyson
Fri 8/28
6:12 pm-8:08 pm
1 stop2h 56m
Panama City NW Florida Beaches
Fri 9/4
1:53 pm-8:03 pm
1 stop5h 10m
$299
KnoxvillePanama City
TYS - ECP
TYSECP
Knoxville McGhee Tyson
Wed 8/19
7:00 am-5:00 pm
2 stops11h 00m
Panama City NW Florida Beaches
Mon 8/31
7:05 am-5:10 pm
2 stops9h 05m
$369
Showing 1-10 of 23 resultsSorted by cheapest first
Best time to book a flight from Knoxville to Panama City Beach
Have a flexible travel schedule? Discover the best time to fly to Panama City Beach from Knoxville with our price prediction graph.
TYS-ECP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Knoxville to Panama City Beach
TYS-PA9
TYS-ECP
What is the cheapest time of day to fly from TYS to PA9?
Find hourly flight availability from Knoxville to Panama City Beach. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 5, 2026.
One of the essential ways to save on airfare from Knoxville to Panama City Beach is to remain as flexible as possible. Flights that are in the evening tend to be the most expensive. A flight in the morning could potentially save you up to 17% on airfare.
How much does it cost to fly round-trip from Knoxville to Panama City Beach?
Airfare is below average for this route at the moment.
Knoxville to Panama City Beach flights typically cost between $278 and $393 in September.The cheapest round-trip price found within the last 5 days was $245 on Delta (Sep 11-Sep 16).
Reviews of airlines servicing Panama City Beach
Get insights into the airlines that provide service to Panama City Beach. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City Beach. Reviews last updated August 5, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andAmerican Airlines from Knoxville to Panama City Beach to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.5
Food
7.0
Crew
8.6
Boarding
8.1
Overall
8.0
Comfort
8.0
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Entertainment
7.5
Food
7.0
Crew
8.6
Boarding
8.1
Overall
8.0
Comfort
8.0
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Entertainment
7.5
Food
7.0
Crew
8.6
Boarding
8.1
Overall
8.0
Comfort
8.0
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Entertainment
7.5
Food
7.0
Crew
8.6
Boarding
8.1
Overall
8.0
Comfort
8.0
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Related info for your journey
Find useful and relevant information for your journey from Knoxville to Panama City Beach. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Knoxville to Panama City Beach
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Complete your trip
Complete your trip to Panama City Beach by adding a car rental and/or hotel reservation to your travel itinerary.
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Knoxville and Panama City Beach flights
Browse other Knoxville and Panama City Beach flight options. Last updated on August 5, 2026.
Other flights from Knoxville
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Knoxville to Panama City Beach flights
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Top 4 airlines flying from Knoxville to Panama City Beach
Discover the top 4 airlines that operate flights from Knoxville to Panama City Beach. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 5, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$84 | Average$146 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$124 | Average$382 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$247 | Average$335 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$306 | Average$498 | FlexibilityNo cancel fee | On-time71% |