Panama

$126+ Cheap flights from Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/22. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — JFK
May 19 — May 261
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What to know about flights from Panama

Discover essential information about flights departing from Panama, including flight schedules, destinations, airlines operating at the Panama airport, and any specific guidelines or requirements for travelers. Please note that the information is based on the most recent updates available. Data last updated May 14, 2025.

Good round-trip deal

$37 or less

Good one-way deal

$37 or less
Price to beat on a round-trip flight from Panama.
Price to beat on a one-way flight from Panama.

Find flights from Panama

Cheapest flights from Panama
Explore the most affordable flight options available from Panama. Find the lowest fares based on data from user searches, with prices last updated on May 14, 2025.

Fri 6/61:16 pmPTY - MDE
Nonstop1h 25mCopa Airlines
Fri 6/1310:46 amMDE - PTY
Nonstop1h 30mCopa Airlines
Deal found 5/13$213
Mon 6/911:20 amPTY - MDE
Nonstop1h 10mAvianca
Sun 6/155:55 pmMDE - PTY
Nonstop1h 20mAvianca
Deal found 5/12$236
Tue 7/228:10 pmPTY - MIA
2 stops16h 45mAvianca
Sun 7/278:15 amMIA - PTY
1 stop12h 00mAvianca
Deal found 5/13$262
Tue 5/278:10 amPTY - MIA
Nonstop3h 15mCopa Airlines
Sun 6/16:01 amMIA - PTY
Nonstop3h 10mCopa Airlines
Deal found 5/13$275
Tue 5/203:20 amPTY - CUN
1 stop11h 20mAvianca
Mon 5/2612:45 pmCUN - PTY
1 stop11h 25mAvianca
Deal found 5/13$285
Fri 6/137:11 amPTY - CUN
Nonstop2h 49mCopa Airlines
Tue 6/174:42 pmCUN - PTY
Nonstop2h 41mCopa Airlines
Deal found 5/13$293
Sun 6/11:20 pmPTY - JFK
1 stop9h 48mAmerican Airlines
Sun 6/89:30 pmJFK - PTY
2 stops16h 30mAmerican Airlines
Deal found 5/13$314
Mon 6/161:50 pmPTY - MIA
Nonstop3h 05mAmerican Airlines
Sun 6/2212:10 pmMIA - PTY
Nonstop3h 15mAmerican Airlines
Deal found 5/13$316
Fri 6/273:40 pmPTY - MEX
1 stop11h 15mAvianca
Thu 7/312:40 amMEX - PTY
1 stop8h 30mAvianca
Deal found 5/13$316
Fri 10/312:12 pmPTY - MIA
1 stop9h 40mDelta
Tue 11/47:00 amMIA - PTY
1 stop6h 47mDelta
Deal found 5/13$322
Wed 10/81:50 pmPTY - LGA
1 stop8h 59mAmerican Airlines
Wed 10/155:07 amLGA - PTY
1 stop8h 18mAmerican Airlines
Deal found 5/13$329
Thu 7/2410:19 pmPTY - MEX
Nonstop3h 41mCopa Airlines
Tue 7/295:50 amMEX - PTY
Nonstop3h 44mCopa Airlines
Deal found 5/13$339

Find flights from Panama within your budget

Find flights departing from Panama that match your specified budget. Filter results by price range, allowing you to narrow down options and find flights that fit within your financial constraints. Please note that the search results are based on data from user searches, with fares last updated on May 14, 2025. In the last 7 days, Cheapflights users made a total of 2,558,603 searches

Fly to

John F Kennedy Intl

Route

Depart

Return

Price

Panama CityMedellín

PTY - MDE

PTYMDE

Panama City Tocumen Intl

Fri 6/6

6:33 pm-7:57 pm

Nonstop1h 24m

Medellín Jose Maria Cordova Intl

Mon 6/9

11:29 am-12:56 pm

Nonstop1h 27m

$213

Panama CityMedellín

PTY - MDE

PTYMDE

Panama City Tocumen Intl

Thu 5/29

3:40 pm-4:55 pm

Nonstop1h 15m

Medellín Jose Maria Cordova Intl

Sun 6/1

1:25 pm-2:40 pm

Nonstop1h 15m

$235

Panama CityMiami

PTY - MIA

PTYMIA

Panama City Tocumen Intl

Tue 7/22

8:10 pm-1:55 pm

2 stops16h 45m

Miami

Sun 7/27

8:15 am-7:15 pm

1 stop12h 00m

$262

Panama CityMiami

PTY - MIA

PTYMIA

Panama City Tocumen Intl

Mon 7/28

6:32 pm-10:43 pm

Nonstop3h 11m

Miami

Tue 8/5

5:23 pm-7:29 pm

Nonstop3h 06m

$273

Panama CityMiami

PTY - MIA

PTYMIA

Panama City Tocumen Intl

Sat 5/24

2:13 pm-1:15 pm

1 stop22h 02m

Miami

Wed 5/28

5:35 am-12:48 pm

1 stop8h 13m

$284

Panama CityCancún

PTY - CUN

PTYCUN

Panama City Tocumen Intl

Sat 11/1

3:19 am-5:00 pm

1 stop13h 41m

Cancun

Thu 11/6

3:50 pm-1:00 am

1 stop9h 10m

$285

Panama CityCancún

PTY - CUN

PTYCUN

Panama City Tocumen Intl

Mon 6/9

7:55 am-10:44 am

Nonstop2h 49m

Cancun

Thu 6/19

11:42 am-2:23 pm

Nonstop2h 41m

$293

Panama CityMiami

PTY - MIA

PTYMIA

Panama City Tocumen Intl

Wed 8/20

3:40 pm-7:45 pm

Nonstop3h 05m

Miami

Wed 8/27

12:05 pm-2:20 pm

Nonstop3h 15m

$310

Panama CityNew York

PTY - JFK

PTYJFK

Panama City Tocumen Intl

Sun 6/1

1:20 pm-12:08 am

1 stop9h 48m

New York John F Kennedy Intl

Sun 6/8

9:30 pm-1:00 pm

2 stops16h 30m

$314

Panama CityMexico City

PTY - MEX

PTYMEX

Panama City Tocumen Intl

Fri 6/27

3:40 pm-1:55 am

1 stop11h 15m

Mexico City Benito Juarez

Thu 7/3

12:40 am-10:10 am

1 stop8h 30m

$316

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/13

Showing 1-10 of 60 results
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Best time to book a flight from Panama

Have a flexible travel schedule? Discover the best time to fly from Panama with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Panama

Get recent, data-driven insights about flights from Panama including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Panama?

Currently, January is the cheapest month in which you can book a flight from Panama (average of $169). Flying from Panama in July will prove the most costly (average of $484). There are multiple factors that influence the price of a flight so comparing airlines, departure airports and times can help keep costs down.

Airline reviews for flights from Panama

Read reviews and ratings of airlines operating flights from Panama. Gain insights into the quality of service, in-flight amenities, customer experiences, and overall satisfaction to choose the best airline for your Panama travel. Please note that the reviews are sourced from user searches and were last updated on May 14, 2025. In the last 7 days, Cheapflights users made a total of 2,558,603 searches.
8.0
Very good

Crew

8.5

Entertainment

7.9

Comfort

7.9

Overall

8.0

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Lucy,Nov 2023

ATL - JFK

On time flights; courteous staff; efficient boarding system! Thank you!
8.0
Very good
8.0
Very good

Crew

8.5

Entertainment

7.9

Comfort

7.9

Overall

8.0

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Lucy,Nov 2023

ATL - JFK

On time flights; courteous staff; efficient boarding system! Thank you!
8.0
Very good

Crew

8.5

Entertainment

7.9

Comfort

7.9

Overall

8.0

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Lucy,Nov 2023

ATL - JFK

On time flights; courteous staff; efficient boarding system! Thank you!
8.0
Very good

Crew

8.5

Entertainment

7.9

Comfort

7.9

Overall

8.0

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Lucy,Nov 2023

ATL - JFK

On time flights; courteous staff; efficient boarding system! Thank you!
8.0
Very good

Crew

8.5

Entertainment

7.9

Comfort

7.9

Overall

8.0

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Lucy,Nov 2023

ATL - JFK

On time flights; courteous staff; efficient boarding system! Thank you!
8.0
Very good

Crew

8.5

Entertainment

7.9

Comfort

7.9

Overall

8.0

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Lucy,Nov 2023

ATL - JFK

On time flights; courteous staff; efficient boarding system! Thank you!

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Related info for your journey

Access useful and relevant information related to your journey from Panama. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated May 14, 2025.
  • What is the cheapest month to fly from Panama?

    January is currently the cheapest month to fly from Panama. At this moment in time July is the most expensive month. These prices are determined by multiple factors and booking in advance can help keep costs down if your schedule is not as flexible.

  • Where are the cheapest places to fly to from Panama?

    Check out the cheapest flights from Panama to embark to:
    Fly from Panama City to Medellín from $139 round trip
    Fly from Panama City to Bogotá from $143 round trip
    Fly from Panama City to Cartagena from $143 round trip
    Fly from Panama City to San José from $182 round trip
    Fly from Panama City to San Salvador from $201 round trip

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