HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Panama

$120+ Cheap flights from Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/13. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — JFK
mai 27 — juin 31
mer. 5/27
mer. 6/3
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find flights from Panama within your budget

 
Find flights departing from Panama that match your specified budget. Filter results by price range, allowing you to narrow down options and find flights that fit within your financial constraints. Please note that the search results are based on data from user searches, with fares last updated on avril 27, 2026. In the last 7 days, Cheapflights users made a total of 2,558,603 searches

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Panama CityBogotá

PTY - BOG

PTYBOG

Panama City Tocumen Intl

ven. 5/29

7:50 am-9:29 am

Nonstop1h 39m

Bogotá El Dorado

dim. 5/31

9:45 am-11:30 am

Nonstop1h 45m

$244

Panama CityBogotá

PTY - BOG

PTYBOG

Panama City Tocumen Intl

jeu. 5/7

11:50 am-1:29 pm

Nonstop1h 39m

Bogotá El Dorado

jeu. 5/7

4:45 pm-6:30 pm

Nonstop1h 45m

$244

Panama CityMedellín

PTY - MDE

PTYMDE

Panama City Tocumen Intl

dim. 5/10

7:11 pm-8:35 pm

Nonstop1h 24m

Medellín Jose Maria Cordova Intl

dim. 5/17

10:35 am-12:03 pm

Nonstop1h 28m

$289
Quickest round-trip

Panama CityMedellín

PTY - MDE

PTYMDE

Panama City Tocumen Intl

jeu. 5/7

6:54 am-8:15 am

Nonstop1h 21m

Medellín Jose Maria Cordova Intl

jeu. 5/21

6:20 pm-7:48 pm

Nonstop1h 28m

$289

Panama CityMedellín

PTY - MDE

PTYMDE

Panama City Tocumen Intl

jeu. 6/4

6:49 am-8:15 am

Nonstop1h 26m

Medellín Jose Maria Cordova Intl

sam. 6/6

6:20 pm-7:47 pm

Nonstop1h 27m

$289

Panama CityMedellín

PTY - MDE

PTYMDE

Panama City Tocumen Intl

mar. 6/2

1:19 pm-2:45 pm

Nonstop1h 26m

Medellín Jose Maria Cordova Intl

sam. 6/6

8:35 am-10:02 am

Nonstop1h 27m

$289

Panama CityMedellín

PTY - MDE

PTYMDE

Panama City Tocumen Intl

sam. 5/30

1:21 pm-2:45 pm

Nonstop1h 24m

Medellín Jose Maria Cordova Intl

mar. 6/2

10:35 am-12:02 pm

Nonstop1h 27m

$289

Panama CityMedellín

PTY - MDE

PTYMDE

Panama City Tocumen Intl

ven. 6/19

6:49 am-8:15 am

Nonstop1h 26m

Medellín Jose Maria Cordova Intl

mar. 6/23

4:30 pm-5:57 pm

Nonstop1h 27m

$289

Panama CityMedellín

PTY - MDE

PTYMDE

Panama City Tocumen Intl

mer. 6/3

12:49 pm-2:15 pm

Nonstop1h 26m

Medellín Jose Maria Cordova Intl

mer. 6/10

4:30 pm-5:57 pm

Nonstop1h 27m

$289

Panama CityMedellín

PTY - MDE

PTYMDE

Panama City Tocumen Intl

mar. 5/26

1:21 pm-2:45 pm

Nonstop1h 24m

Medellín Jose Maria Cordova Intl

sam. 5/30

12:40 pm-2:08 pm

Nonstop1h 28m

$289

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/23

Showing 1-10 of 60 resultsSorted by cheapest first
1
2
3
...
6

Best time to book a flight from Panama

Have a flexible travel schedule? Discover the best time to fly from Panama with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Panama

Get recent, data-driven insights about flights from Panama including ideal travel times, pricing trends, and more.

When is the best time to book a flight from Panama?

To ensure you get the cheapest price possible for a flight from Panama, you should look to book at least 35 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Panama?

Currently, March is the cheapest month in which you can book a flight from Panama (average of $76). Flying from Panama in October will prove the most costly (average of $959). There are multiple factors that influence the price of a flight so comparing airlines, departure airports and times can help keep costs down.

Which airlines fly from Panama?

For flights departing from Panama check dates and pricing for the following: Copa Airlines, Avianca, American Airlines. These airlines depart to the following popular destinations: New York.

Copa Airlines
Copa Airlines
From $71
Avianca
Avianca
From $94
Wingo
Wingo
From $26
United Airlines
United Airlines
From $164

What is the cheapest place to fly to from Panama?

The cheapest city to fly to from Panama is David Enrique Malek, with prices starting at $28. Explore other affordable destinations below.

David Enrique Malek
David Enrique Malek
From $28
Medellín Jose Maria Cordova Intl
Medellín Jose Maria Cordova Intl
From $55
Bogotá El Dorado
Bogotá El Dorado
From $67
Cartagena Rafael Nunez
Cartagena Rafael Nunez
From $67

Airline reviews for flights from Panama

Read reviews and ratings of airlines operating flights from Panama. Gain insights into the quality of service, in-flight amenities, customer experiences, and overall satisfaction to choose the best airline for your Panama travel. Please note that the reviews are sourced from user searches and were last updated on avril 27, 2026. In the last 7 days, Cheapflights users made a total of 2,558,603 searches.
Read reviews from past customers who have flown Copa Airlines,American Airlines, andAvianca from Panama. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.5
Good
1,580 reviews

Crew

8.1

Food

6.8

Entertainment

6.8

Comfort

7.4

Boarding

7.8

Overall

7.5

Reviews

1 / 20
2.0
Mediocre

Maria,Dec 2025

PTY - SLA

Old plain no entertainment , no outlet for cell or computer! And online they said you have all that! Almost 6 hrs looking to the floor..terrible expirencw and I pay a lot of money for it
Copa Airlines
7.5
Good
1,580 reviews
Copa Airlines
7.5
Good
1,580 reviews

Crew

8.1

Food

6.8

Entertainment

6.8

Comfort

7.4

Boarding

7.8

Overall

7.5

Reviews

1 / 20
2.0
Mediocre

Maria,Dec 2025

PTY - SLA

Old plain no entertainment , no outlet for cell or computer! And online they said you have all that! Almost 6 hrs looking to the floor..terrible expirencw and I pay a lot of money for it
American Airlines
7.1
Good
11,668 reviews
Copa Airlines
7.5
Good
1,580 reviews

Crew

8.1

Food

6.8

Entertainment

6.8

Comfort

7.4

Boarding

7.8

Overall

7.5

Reviews

1 / 20
2.0
Mediocre

Maria,Dec 2025

PTY - SLA

Old plain no entertainment , no outlet for cell or computer! And online they said you have all that! Almost 6 hrs looking to the floor..terrible expirencw and I pay a lot of money for it
Avianca
6.5
Okay
2,513 reviews
Copa Airlines
7.5
Good
1,580 reviews

Crew

8.1

Food

6.8

Entertainment

6.8

Comfort

7.4

Boarding

7.8

Overall

7.5

Reviews

1 / 20
2.0
Mediocre

Maria,Dec 2025

PTY - SLA

Old plain no entertainment , no outlet for cell or computer! And online they said you have all that! Almost 6 hrs looking to the floor..terrible expirencw and I pay a lot of money for it

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Related info for your journey

Access useful and relevant information related to your journey from Panama. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated avril 27, 2026.

  • What is the cheapest month to fly from Panama?

    March is currently the cheapest month to fly from Panama. At this moment in time October is the most expensive month. These prices are determined by multiple factors and booking in advance can help keep costs down if your schedule is not as flexible.

  • Where are the cheapest places to fly to from Panama?

    Check out the cheapest flights from Panama to embark to:
    Fly from Panama City to Bogotá from $136 round trip
    Fly from Panama City to Medellín from $138 round trip
    Fly from Panama City to Cartagena from $140 round trip
    Fly from Panama City to San José from $260 round trip
    Fly from Panama City to San Salvador from $279 round trip

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.