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Panama

$144+ Cheap flights from Panama

PTY — JFK
Oct 8 — Oct 151
Thu 10/8
Thu 10/15
1 adult, Economy
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Find flights from Panama within your budget

 

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Route

Depart

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Price

Cheapest round-trip

Panama CityMedellín

PTY Panama City Tocumen Intl - MDE Medellín Jose Maria Cordova Intl

PTYMDE

Panama City Tocumen Intl

Wed 10/14

1:20 pm-2:45 pm

Nonstop1h 25m

Medellín Jose Maria Cordova Intl

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$146
Quickest round-trip

Panama CityMedellín

PTY Panama City Tocumen Intl - MDE Medellín Jose Maria Cordova Intl

PTYMDE

Panama City Tocumen Intl

Sun 11/15

6:57 am-8:15 am

Nonstop1h 18m

Medellín Jose Maria Cordova Intl

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$146

Panama CityMedellín

PTY Panama City Tocumen Intl - MDE Medellín Jose Maria Cordova Intl

PTYMDE

Panama City Tocumen Intl

Sat 10/31

12:50 pm-2:15 pm

Nonstop1h 25m

Medellín Jose Maria Cordova Intl

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$146

Panama CityMedellín

PTY Panama City Tocumen Intl - MDE Medellín Jose Maria Cordova Intl

PTYMDE

Panama City Tocumen Intl

Mon 9/21

1:20 pm-2:45 pm

Nonstop1h 25m

Medellín Jose Maria Cordova Intl

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$146

Panama CityMedellín

PTY Panama City Tocumen Intl - MDE Medellín Jose Maria Cordova Intl

PTYMDE

Panama City Tocumen Intl

Mon 11/23

1:25 pm-2:45 pm

Nonstop1h 20m

Medellín Jose Maria Cordova Intl

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$146

Panama CityMedellín

PTY Panama City Tocumen Intl - MDE Medellín Jose Maria Cordova Intl

PTYMDE

Panama City Tocumen Intl

Tue 10/6

1:20 pm-2:45 pm

Nonstop1h 25m

Medellín Jose Maria Cordova Intl

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$146

Panama CityMedellín

PTY Panama City Tocumen Intl - MDE Medellín Jose Maria Cordova Intl

PTYMDE

Panama City Tocumen Intl

Tue 11/24

12:54 pm-2:15 pm

Nonstop1h 21m

Medellín Jose Maria Cordova Intl

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$146

Panama CityMedellín

PTY Panama City Tocumen Intl - MDE Medellín Jose Maria Cordova Intl

PTYMDE

Panama City Tocumen Intl

Fri 9/18

6:50 am-8:15 am

Nonstop1h 25m

Medellín Jose Maria Cordova Intl

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$146

Panama CityMedellín

PTY Panama City Tocumen Intl - MDE Medellín Jose Maria Cordova Intl

PTYMDE

Panama City Tocumen Intl

Mon 9/28

12:50 pm-2:15 pm

Nonstop1h 25m

Medellín Jose Maria Cordova Intl

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$146

Panama CityMedellín

PTY Panama City Tocumen Intl - MDE Medellín Jose Maria Cordova Intl

PTYMDE

Panama City Tocumen Intl

Tue 9/15

12:50 pm-2:15 pm

Nonstop1h 25m

Medellín Jose Maria Cordova Intl

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$146

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/7

Showing 1-10 of 60 resultsSorted by cheapest first
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Best time to book a flight from Panama

Have a flexible travel schedule? Discover the best time to fly from Panama with our price prediction graph.
Estimated round-trip price

Travel insights for flights from Panama

Get recent, data-driven insights about flights from Panama including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Panama?

Currently, April is the cheapest month in which you can book a flight from Panama (average of $562). Flying from Panama in August will prove the most costly (average of $736). There are multiple factors that influence the price of a flight so comparing airlines, departure airports and times can help keep costs down.

Which airlines fly from Panama?

For flights departing from Panama check dates and pricing for the following: Copa Airlines, Avianca, American Airlines, Delta. These airlines depart to the following popular destinations: New York.

Copa Airlines
Copa Airlines
From $85
Avianca
Avianca
From $94
United Airlines
United Airlines
From $224
Wingo
Wingo
From $69

What is the cheapest place to fly to from Panama?

The cheapest city to fly to from Panama is David Enrique Malek, with prices starting at $28. Explore other affordable destinations below.

David Enrique Malek
David Enrique Malek
From $28
Panama City Tocumen Intl
Panama City Tocumen Intl
From $64
Bocas Del Toro
Bocas Del Toro
From $65
Cali Alfonso B. Aragon Intl
Cali Alfonso B. Aragon Intl
From $68

When is the best time to book a flight from Panama?

To ensure you get the cheapest price possible for a flight from Panama, you should look to book at least 40 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

Airline reviews for flights from Panama

Read reviews from past customers who have flown Delta,Copa Airlines, andAmerican Airlines from Panama. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.8
Good
8,548 reviews

Comfort

7.8

Boarding

8.1

Crew

8.5

Overall

7.8

Entertainment

7.8

Food

7.2

Reviews

1 / 20
10.0
Excellent

Sally,Oct 2025

ATH - JFK

Only negative outcome of this trip was 3 hour delay, but everything else was fine.
Delta
7.8
Good
8,548 reviews
Delta
7.8
Good
8,548 reviews

Comfort

7.8

Boarding

8.1

Crew

8.5

Overall

7.8

Entertainment

7.8

Food

7.2

Reviews

1 / 20
10.0
Excellent

Sally,Oct 2025

ATH - JFK

Only negative outcome of this trip was 3 hour delay, but everything else was fine.
Copa Airlines
7.6
Good
1,544 reviews
Delta
7.8
Good
8,548 reviews

Comfort

7.8

Boarding

8.1

Crew

8.5

Overall

7.8

Entertainment

7.8

Food

7.2

Reviews

1 / 20
10.0
Excellent

Sally,Oct 2025

ATH - JFK

Only negative outcome of this trip was 3 hour delay, but everything else was fine.
American Airlines
7.1
Good
12,042 reviews
Delta
7.8
Good
8,548 reviews

Comfort

7.8

Boarding

8.1

Crew

8.5

Overall

7.8

Entertainment

7.8

Food

7.2

Reviews

1 / 20
10.0
Excellent

Sally,Oct 2025

ATH - JFK

Only negative outcome of this trip was 3 hour delay, but everything else was fine.
Avianca
6.5
Okay
2,554 reviews
Delta
7.8
Good
8,548 reviews

Comfort

7.8

Boarding

8.1

Crew

8.5

Overall

7.8

Entertainment

7.8

Food

7.2

Reviews

1 / 20
10.0
Excellent

Sally,Oct 2025

ATH - JFK

Only negative outcome of this trip was 3 hour delay, but everything else was fine.

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Related info for your journey

  • What is the cheapest month to fly from Panama?

    April is currently the cheapest month to fly from Panama. At this moment in time August is the most expensive month. These prices are determined by multiple factors and booking in advance can help keep costs down if your schedule is not as flexible.

  • Where are the cheapest places to fly to from Panama?

    Check out the cheapest flights from Panama to embark to:
    Fly from Panama City to Bogotá from $138 round trip
    Fly from Panama City to Medellín from $140 round trip
    Fly from Panama City to Cartagena from $152 round trip
    Fly from Panama City to San José from $254 round trip
    Fly from Panama City to Guatemala City from $276 round trip

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