For US-bound flights, expect two security checks at PTY, with the second at the gate. Allow extra time for this process.

Most accurate provider | eDreams 3 stars |
|---|---|
Most trusted provider | eDreams 3 stars |
Round-trip from | $547 (Mytrip) |
One-way from | $247 (Avianca Connect) |
Popular in | March |
Cheapest in | September |
Average price | $702 |
Fly from
Fly to
Route
Depart
Return
Price
Panama CityLas Vegas
PTY - LAS
PTYLAS
Panama City Tocumen Intl
Tue 4/7
3:20 am-12:04 am
2 stops22h 44m
Las Vegas Harry Reid Intl
Tue 5/12
11:31 am-1:55 am
2 stops12h 24m
Panama CityLas Vegas
PTY - LAS
PTYLAS
Panama City Tocumen Intl
Sat 2/14
10:26 am-9:48 pm
1 stop14h 22m
Las Vegas Harry Reid Intl
Wed 2/18
11:59 pm-8:34 pm
1 stop17h 35m
Panama CityLas Vegas
PTY - LAS
PTYLAS
Panama City Tocumen Intl
Sat 4/4
7:55 am-3:49 pm
1 stop9h 54m
Las Vegas Harry Reid Intl
Sun 4/5
12:36 am-4:12 pm
1 stop13h 36m
Panama CityLas Vegas
PTY - LAS
PTYLAS
Panama City Tocumen Intl
Thu 4/2
2:28 pm-11:29 pm
1 stop11h 01m
Las Vegas Harry Reid Intl
Wed 4/8
12:55 am-1:03 pm
1 stop10h 08m
Panama CityLas Vegas
PTY - LAS
PTYLAS
Panama City Tocumen Intl
Mon 4/6
10:00 am-8:38 pm
2 stops12h 38m
Las Vegas Harry Reid Intl
Sun 4/12
6:00 am-6:37 pm
2 stops10h 37m
Panama CityLas Vegas
PTY - LAS
PTYLAS
Panama City Tocumen Intl
Tue 3/31
7:55 am-3:49 pm
1 stop9h 54m
Las Vegas Harry Reid Intl
Mon 4/6
6:00 am-4:12 pm
1 stop8h 12m
Panama CityLas Vegas
PTY - LAS
PTYLAS
Panama City Tocumen Intl
Sun 4/5
10:00 am-8:12 pm
1 stop12h 12m
Las Vegas Harry Reid Intl
Sat 4/11
5:20 am-6:37 pm
2 stops11h 17m
Panama CityLas Vegas
PTY - LAS
PTYLAS
Panama City Tocumen Intl
Mon 4/6
10:00 am-8:38 pm
2 stops12h 38m
Las Vegas Harry Reid Intl
Thu 4/9
6:00 am-6:37 pm
1 stop10h 37m
Panama CityLas Vegas
PTY - LAS
PTYLAS
Panama City Tocumen Intl
Thu 4/2
10:00 am-8:40 pm
2 stops12h 40m
Las Vegas Harry Reid Intl
Thu 4/9
6:00 am-6:37 pm
1 stop10h 37m
Panama CityLas Vegas
PTY - LAS
PTYLAS
Panama City Tocumen Intl
Sat 4/4
7:55 am-4:37 pm
1 stop10h 42m
Las Vegas Harry Reid Intl
Sun 4/12
6:00 am-6:37 pm
1 stop10h 37m
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*1 star | |
| Price Accuracy2 stars | Trust Score*3 stars |
Booking 63 days in advance of your planned departure date is, on average, the best time to get cheap flights from Panama City to Las Vegas. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
Currently, August is the cheapest month in which you can book a flight from Panama City to Las Vegas (average of $468). Flying from Panama City to Las Vegas in April is currently the most expensive (average of $589). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
When flying from Panama City to Las Vegas, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
About 1% of weekly flights between Panama City and Las Vegas have experienced delays in the past year, with the average delay time being 128 minutes.
Historically, flights departing in the early afternoon are less likely to be delayed, whereas flights leaving in the evening tend to experience delays more often.
Wednesday tends to have the lowest number of delays on this route, whereas Thursday has historically faced a higher average of delays compared to other days of the week.
Over the last year, Copa Airlines have had the lowest number of delays on this route, with just 1% of flights being delayed.
Comfort
Boarding
Entertainment
Food
Overall
Crew
Reviews
Jim,Nov 2025
AVL - ATL
Comfort
Boarding
Entertainment
Food
Overall
Crew
Reviews
Jim,Nov 2025
AVL - ATL
Comfort
Boarding
Entertainment
Food
Overall
Crew
Reviews
Jim,Nov 2025
AVL - ATL
Comfort
Boarding
Entertainment
Food
Overall
Crew
Reviews
Jim,Nov 2025
AVL - ATL
Comfort
Boarding
Entertainment
Food
Overall
Crew
Reviews
Jim,Nov 2025
AVL - ATL
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$488 | Average$643 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$493 | Average$583 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$504 | Average$620 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$532 | Average$660 | FlexibilityNo cancel fee | On-time69% |