What is the most punctual flight time for Guatemala City to San Francisco flights?

Historically, flights departing in the early afternoon are less likely to be delayed, whereas flights leaving in the early afternoon tend to experience delays more often.

Which airport typically offers the quickest layover for flights from Guatemala City to San Francisco?

Flights via San Salvador (SAL) offer the fastest connection on this route, with an average layover time of 2h 54m.

What’s the cheapest layover airport for flights from Guatemala City to San Francisco?

San Salvador (SAL) is the most affordable 1-stop option, with an average round-trip price of $360.

What day of the week experiences the fewest flight delays on this route?

Thursday tends to have the lowest number of delays on this route, whereas Thursday has historically faced a higher average of delays compared to other days of the week.

What’s the fastest layover option from Guatemala City to San Francisco?

Flights via Houston (IAH) have the shortest average one-way travel time for 1-stop routes: 10h 07m.

What’s the top layover airport for flights from Guatemala City to San Francisco?

Houston (IAH) – chosen by Cheapflights users on 52% of 1-stop itineraries from Guatemala City to San Francisco on Cheapflights.

How long is the flight from Guatemala City to San Francisco?

There are many flights that can get you from Guatemala City to San Francisco in 9h 30m. Fly via United Airlines to get the fastest option. There are 2514 mi between Guatemala City and San Francisco.

What are the cheapest airlines flying from Guatemala City to San Francisco round-trip?

Our cheapest airline available from Guatemala City to San Francisco is Avianca. Our recent data shows that you can find tickets from as low as $266 on this airline. Additional options worth looking into are United Airlines and American Airlines, starting at $289 and $361 round-trip. Users have found that Avianca is 35% cheaper than the other options available to this destination.

What are the cheapest airlines to fly from Guatemala City to San Francisco one-way?

The cheapest airlines for a one-way flight from Guatemala City to San Francisco are Volaris El Salvador ($135), American Airlines ($157), and Avianca ($159).

In terms of precipitation, rainfall in San Francisco ranges from 0.0 - 4.4 inches per month. January is typically the wettest month, when rainfall can reach 4.4 in. July is typically the driest time to visit San Francisco when rainfall is around 0.0 in.

If weather is an important factor for your trip to San Francisco, use this chart to help with planning. For those seeking warmer temperatures, September is the ideal time of year to visit, when temperatures reach an average of 62.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 51.8 F).

What are the cheapest flights from Guatemala City to San Francisco?

The cheapest flight price from Guatemala City to San Francisco is $255. On average you can expect to pay $565. The most popular route, (Guatemala City La Aurora - San Francisco), can usually be booked for $380.

What are the most popular airlines that fly from Guatemala City to San Francisco?

The most popular airlines flying from Guatemala City to San Francisco are Avianca, United Airlines and American Airlines. Something to consider prior to booking your flight.

Where are the most common layover locations when flying from Guatemala City to San Francisco?

Most of the time, Guatemala City to San Francisco flights that have layovers will stop in San Salvador. San Salvador is followed by Houston in terms of the most popular layover location on flights from Guatemala City to San Francisco.

Where are the least popular layover locations for Guatemala City to San Francisco flights?

Guatemala City to San Francisco flights that have layovers will least frequently stop in Los Angeles.

What are some popular points of interest to see during a layover in Houston?

The majority of Houston visitors spend their time at Space Center Houston, House of Blues Houston, and Bayou Music Center. Space Center Houston, House of Blues Houston, and Bayou Music Center are located about 33.5 mi, 16.1 mi, and 15.5 mi, respectively from Houston George Bush Intcntl. Travelers can rent a car at Houston George Bush Intcntl for an average daily rate of $41 to make sightseeing during their layover a little easier.

What is the cheapest time of day to fly from GUA to SFO?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Guatemala City to San Francisco as you normally would.

Most accurate provider : When it comes to deals on Guatemala City-San Francisco flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Guatemala City-San Francisco flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Guatemala City-San Francisco flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Guatemala City-San Francisco flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Guatemala City-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Can I find deals for flights from Guatemala City to San Francisco that include hotel bookings?

Yes. In addition to deals on Guatemala City to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Guatemala City to San Francisco?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Guatemala City to San Francisco.

Can I find deals for business class flights from Guatemala City to San Francisco?

Yes. Cheapflights offers flight deals from Guatemala City to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$216+ Cheap Flights from Guatemala City to San Francisco

Q: How often are flights from Guatemala City to San Francisco delayed?

About 100% of weekly flights between Guatemala City and San Francisco have experienced delays in the past year, with the average delay time being 248 minutes.

Q: How much does it cost to fly round-trip from Guatemala City to San Francisco?

Airfare is below average for this route at the moment. Guatemala City to San Francisco flights typically cost between $473 and $336 in July. The cheapest round-trip price found within the last 3 days was $369 on Frontier (Jul 9-Aug 29).

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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

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Cheapflights Tip: The best prices from Guatemala City La Aurora to San Francisco are usually found in February or October, booked 68 days in advance, depart on a Monday or Wednesday and return on a Monday

Cheap flight deals from Guatemala City to San Francisco

Cheapest

Best

Last-minute

One-way

Cheapest flights from Guatemala City to San Francisco
Explore the most affordable flight options available from Guatemala City to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 28, 2026.

Thu 7/911:16 am

GUA

SFO

1 stop12h 38m

Frontier

Sat 8/298:51 pm

SFO

GUA

1 stop16h 51m

Frontier

Deal found 4/27

$369

Thu 8/1311:16 am

GUA

SFO

1 stop12h 38m

Frontier

Fri 8/218:51 pm

SFO

GUA

1 stop16h 51m

Frontier

Deal found 4/23

$373

Wed 12/234:55 pm

GUA

SFO

1 stop8h 59m

United Airlines

Fri 1/85:00 am

SFO

GUA

1 stop12h 39m

United Airlines

Deal found 4/24

$380

Mon 8/242:25 pm

GUA

SFO

2 stops20h 42m

GOL

Mon 8/3111:30 pm

SFO

GUA

2 stops17h 52m

GOL

Deal found 4/23

$387

Sun 6/143:47 pm

GUA

SFO

1 stop19h 47m

Frontier

Sat 8/298:51 pm

SFO

GUA

1 stop16h 51m

Frontier

Deal found 4/27

$392

Thu 9/1012:04 pm

GUA

SFO

1 stop21h 51m

GOL

Sun 9/134:21 pm

SFO

GUA

2 stops20h 03m

GOL

Deal found 4/25

$397

Thu 6/43:55 pm

GUA

SFO

2 stops49h 40m

Frontier

Wed 7/2912:24 am

SFO

GUA

1 stop8h 46m

Frontier

Deal found 4/26

$400

Mon 12/212:10 am

GUA

SFO

1 stop23h 44m

United Airlines

Sat 1/97:10 pm

SFO

GUA

1 stop22h 29m

United Airlines

Deal found 4/24

$401

Wed 9/236:15 am

GUA

SFO

1 stop9h 24m

United Airlines

Fri 10/212:45 am

SFO

GUA

1 stop9h 39m

United Airlines

Deal found 4/24

$406

Wed 8/51:20 am

GUA

SFO

Nonstop6h 05m

Multiple Airlines

Wed 8/1911:52 pm

SFO

GUA

1 stop9h 14m

Multiple Airlines

Deal found 4/24

$408

Wed 6/31:34 am

GUA

SFO

1 stop8h 56m

Multiple Airlines

Fri 8/288:51 pm

SFO

GUA

1 stop16h 51m

Multiple Airlines

Deal found 4/23

$413

Best flights from Guatemala City to San Francisco
Discover carefully curated flight deals from Guatemala City to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 28, 2026.

Mon 6/13:45 pm

GUA

SFO

1 stop9h 30m

United Airlines

Wed 8/266:54 pm

SFO

GUA

1 stop15h 30m

United Airlines

Deal found 4/23

$436

Mon 7/136:15 am

GUA

SFO

1 stop19h 00m

United Airlines

Thu 8/201:56 pm

SFO

GUA

1 stop13h 52m

United Airlines

Deal found 4/23

$436

Mon 5/113:45 pm

GUA

SFO

1 stop16h 30m

United Airlines

Sun 5/1712:45 am

SFO

GUA

1 stop14h 52m

United Airlines

Deal found 4/25

$476

Tue 7/143:45 pm

GUA

SFO

1 stop16h 37m

United Airlines

Mon 8/1711:59 pm

SFO

GUA

1 stop17h 50m

United Airlines

Deal found 4/23

$481

Thu 7/163:45 pm

GUA

SFO

1 stop16h 37m

United Airlines

Mon 8/311:59 pm

SFO

GUA

1 stop13h 31m

United Airlines

Deal found 4/23

$481

Sat 5/303:45 pm

GUA

SFO

1 stop9h 30m

United Airlines

Sat 6/610:37 pm

SFO

GUA

1 stop29h 11m

United Airlines

Deal found 4/24

$493

Wed 4/292:25 am

GUA

SFO

1 stop9h 23m

United Airlines

Wed 5/137:05 pm

SFO

GUA

1 stop8h 43m

United Airlines

Deal found 4/24

$564

Sun 6/72:25 am

GUA

SFO

1 stop17h 13m

United Airlines

Wed 7/812:45 am

SFO

GUA

1 stop14h 52m

United Airlines

Deal found 4/27

$564

Fri 6/56:15 am

GUA

SFO

1 stop19h 00m

United Airlines

Wed 7/811:59 pm

SFO

GUA

1 stop13h 31m

United Airlines

Deal found 4/25

$564

Tue 5/123:45 pm

GUA

SFO

1 stop18h 57m

United Airlines

Tue 5/1911:59 pm

SFO

GUA

1 stop15h 38m

United Airlines

Deal found 4/26

$571

Wed 6/32:25 am

GUA

SFO

1 stop9h 20m

United Airlines

Thu 6/116:00 am

SFO

GUA

1 stop21h 48m

United Airlines

Deal found 4/26

$579

Thu 5/142:25 am

GUA

SFO

1 stop15h 47m

United Airlines

Sun 5/316:00 am

SFO

GUA

1 stop21h 48m

United Airlines

Deal found 4/25

$585

Last-minute flights from Guatemala City to San Francisco
Discover last-minute flight deals from Guatemala City to San Francisco. Data last updated April 28, 2026 and is based on user searches.

Fri 5/19:45 pm

GUA

SFO

2 stops16h 05m

Avianca

Sun 5/36:00 am

SFO

GUA

2 stops26h 00m

Avianca

Deal found 4/23

$474

Wed 5/62:25 am

GUA

SFO

1 stop9h 23m

United Airlines

Tue 5/127:15 am

SFO

GUA

1 stop8h 22m

United Airlines

Deal found 4/24

$476

Thu 5/73:48 pm

GUA

SFO

2 stops27h 43m

Multiple Airlines

Wed 5/133:26 pm

SFO

GUA

1 stop22h 12m

Multiple Airlines

Deal found 4/25

$482

Sat 5/93:45 pm

GUA

SFO

1 stop16h 30m

United Airlines

Sat 5/164:45 pm

SFO

GUA

1 stop17h 40m

United Airlines

Deal found 4/23

$481

Mon 5/119:45 pm

GUA

SFO

2 stops16h 05m

Avianca

Fri 5/156:00 am

SFO

GUA

2 stops16h 10m

Avianca

Deal found 4/23

$478

Wed 5/133:48 pm

GUA

SFO

2 stops27h 33m

Multiple Airlines

Wed 6/1711:57 pm

SFO

GUA

1 stop9h 04m

Multiple Airlines

Deal found 4/26

$418

Thu 5/143:48 pm

GUA

SFO

2 stops27h 43m

Multiple Airlines

Wed 6/1711:57 pm

SFO

GUA

1 stop9h 04m

Multiple Airlines

Deal found 4/26

$463

Sat 5/165:25 am

GUA

SFO

1 stop18h 10m

Avianca

Sat 5/2311:55 pm

SFO

GUA

1 stop17h 35m

Avianca

Deal found 4/22

$483

Tue 5/191:01 pm

GUA

SFO

2 stops21h 42m

GOL

Sun 5/245:23 am

SFO

GUA

1 stop17h 08m

GOL

Deal found 4/23

$443

Tue 5/267:00 am

GUA

SFO

2 stops16h 35m

Avianca

Wed 5/277:45 pm

SFO

GUA

2 stops12h 15m

Avianca

Deal found 4/23

$425

Wed 5/272:25 am

GUA

SFO

1 stop17h 13m

United Airlines

Mon 8/1711:59 pm

SFO

GUA

1 stop10h 25m

United Airlines

Deal found 4/24

$380

Thu 5/286:00 am

GUA

SFO

1 stop18h 59m

American Airlines

Mon 8/1711:30 pm

SFO

GUA

2 stops17h 52m

American Airlines

Deal found 4/24

$451

One-way flights from Guatemala City to San Francisco
Search for one-way flight options from Guatemala City to San Francisco. Find affordable one-way fares based on user searches. Data last updated April 28, 2026.

Thu 6/1111:16 am

GUA

SFO

1 stop12h 46m

Frontier

Deal found 4/23

$216

Tue 5/193:48 pm

GUA

SFO

2 stops28h 55m

Multiple Airlines

Deal found 4/27

$218

Tue 6/22:25 am

GUA

SFO

1 stop13h 28m

Azul

Deal found 4/27

$241

Sat 7/41:50 pm

GUA

SFO

1 stop18h 32m

United Airlines

Deal found 4/23

$242

Fri 5/2212:35 am

GUA

SFO

1 stop9h 22m

American Airlines

Deal found 4/27

$247

Thu 5/213:48 pm

GUA

SFO

2 stops30h 16m

Multiple Airlines

Deal found 4/26

$248

Tue 6/92:25 am

GUA

SFO

1 stop17h 13m

Avianca

Deal found 4/27

$252

Wed 5/273:45 pm

GUA

SFO

1 stop9h 30m

United Airlines

Deal found 4/24

$253

Thu 5/212:25 pm

GUA

SFO

1 stop21h 29m

American Airlines

Deal found 4/27

$254

Fri 6/122:25 am

GUA

SFO

1 stop30h 10m

United Airlines

Deal found 4/26

$260

Fri 6/53:47 pm

GUA

SFO

2 stops28h 49m

Multiple Airlines

Deal found 4/27

$264

Find flight deals from Guatemala City to San Francisco

Most accurate provider	FlightHub 3 stars
Most trusted provider	FlightHub 3 stars
Round-trip from	$369 (Orbitz)
One-way from	$216 (Frontier)
Popular in	March
Cheapest in	February
Average price	$424
Good round-trip deal	$435 or less

Provider with most accurate pricing for Guatemala City La Aurora-San Francisco flight deals.

Search Deals

Provider most trusted by Cheapflights users for Guatemala City La Aurora-San Francisco flights.

Search Deals

From Guatemala City La Aurora to San Francisco

Search Deals

One-way flight from Guatemala City La Aurora to San Francisco

Search Deals

High demand for flights, 0% potential price rise

Search Deals

Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in April 2026

Search Deals

Price to beat on a round-trip flight from Guatemala City La Aurora to San Francisco.

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from Guatemala City to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Guatemala CitySan Francisco

GUA - SFO

GUASFO

Guatemala City La Aurora

Mon 6/1

3:45 pm-12:15 am

1 stop9h 30m

San Francisco

Wed 8/26

6:54 pm-11:24 am

1 stop15h 30m

$436

Guatemala CitySan Francisco

GUA - SFO

GUASFO

Guatemala City La Aurora

Mon 7/13

6:15 am-12:15 am

1 stop19h 00m

San Francisco

Thu 8/20

1:56 pm-4:48 am

1 stop13h 52m

$436

Guatemala CitySan Francisco

GUA - SFO

GUASFO

Guatemala City La Aurora

Mon 5/11

3:45 pm-7:15 am

1 stop16h 30m

San Francisco

Sun 5/17

12:45 am-4:37 pm

1 stop14h 52m

$476

Guatemala CitySan Francisco

GUA - SFO

GUASFO

Guatemala City La Aurora

Tue 7/14

3:45 pm-7:22 am

1 stop16h 37m

San Francisco

Mon 8/17

11:59 pm-6:49 pm

1 stop17h 50m

$481

Guatemala CitySan Francisco

GUA - SFO

GUASFO

Guatemala City La Aurora

Thu 7/16

3:45 pm-7:22 am

1 stop16h 37m

San Francisco

Mon 8/3

11:59 pm-2:30 pm

1 stop13h 31m

$481

Guatemala CitySan Francisco

GUA - SFO

GUASFO

Guatemala City La Aurora

Sat 5/30

3:45 pm-12:15 am

1 stop9h 30m

San Francisco

Sat 6/6

10:37 pm-4:48 am

1 stop29h 11m

$493

Quickest round-trip

Guatemala CitySan Francisco

GUA - SFO

GUASFO

Guatemala City La Aurora

Wed 4/29

2:25 am-10:48 am

1 stop9h 23m

San Francisco

Wed 5/13

7:05 pm-4:48 am

1 stop8h 43m

$564

Guatemala CitySan Francisco

GUA - SFO

GUASFO

Guatemala City La Aurora

Sun 6/7

2:25 am-6:38 pm

1 stop17h 13m

San Francisco

Wed 7/8

12:45 am-4:37 pm

1 stop14h 52m

$564

Guatemala CitySan Francisco

GUA - SFO

GUASFO

Guatemala City La Aurora

Fri 6/5

6:15 am-12:15 am

1 stop19h 00m

San Francisco

Wed 7/8

11:59 pm-2:30 pm

1 stop13h 31m

$564

Guatemala CitySan Francisco

GUA - SFO

GUASFO

Guatemala City La Aurora

Tue 5/12

3:45 pm-9:42 am

1 stop18h 57m

San Francisco

Tue 5/19

11:59 pm-4:37 pm

1 stop15h 38m

$571

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/23

Showing 1-10 of 20 resultsSorted by cheapest first

Compare providers for flights from Guatemala City to San Francisco

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Guatemala City to San Francisco in April.

Provider	Price Accuracy	Trust Score*
Expedia	Price Accuracy1 star	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*3 stars
AranGrant	Price Accuracy3 stars	Trust Score*3 stars
eDreams	Price Accuracy2 stars	Trust Score*3 stars
Cheapflightsfares	Price Accuracy2 stars	Trust Score*1 star
Priceline	Price Accuracy1 star	Trust Score*3 stars
Gotogate	Price Accuracy2 stars	Trust Score*3 stars
BusinessClass	Price Accuracy-	Trust Score*3 stars
oojo	Price Accuracy3 stars	Trust Score*2 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on Guatemala City-San Francisco flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Guatemala City-San Francisco flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Guatemala City-San Francisco flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Guatemala City-San Francisco flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Guatemala City-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Guatemala City to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Guatemala City with our price prediction graph.

GUA-SFO

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Guatemala City to San Francisco

Prices

Delays

How far ahead should I book a flight from Guatemala City to San Francisco?

The price you pay for your flight from Guatemala City to San Francisco may vary depending on when you book. For the best chance of a lower fare, look to book 90 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Guatemala City to San Francisco?

Currently, February is the cheapest month in which you can book a flight from Guatemala City to San Francisco (average of $332). Flying from Guatemala City to San Francisco in March is currently the most expensive (average of $486). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Guatemala City to San Francisco?

Reviews of airlines servicing San Francisco

Read reviews from past customers who have flown Alaska Airlines,United Airlines, andAmerican Airlines from Guatemala City to San Francisco. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Alaska Airlines

7.9

Good

12,309 reviews

Reviews

1 / 20

10.0

Excellent

robert,Feb 2026

LAS - SAN

The good customer service team made you fell welcome on the flight.

Alaska Airlines

7.9

Good

12,309 reviews

Alaska Airlines

7.9

Good

12,309 reviews

Reviews

1 / 20

10.0

Excellent

robert,Feb 2026

LAS - SAN

The good customer service team made you fell welcome on the flight.

United Airlines

7.4

Good

9,672 reviews

Alaska Airlines

7.9

Good

12,309 reviews

Reviews

1 / 20

10.0

Excellent

robert,Feb 2026

LAS - SAN

The good customer service team made you fell welcome on the flight.

American Airlines

7.1

Good

11,676 reviews

Alaska Airlines

7.9

Good

12,309 reviews

Reviews

1 / 20

10.0

Excellent

robert,Feb 2026

LAS - SAN

The good customer service team made you fell welcome on the flight.

Avianca

6.5

Okay

2,514 reviews

Alaska Airlines

7.9

Good

12,309 reviews

Reviews

1 / 20

10.0

Excellent

robert,Feb 2026

LAS - SAN

The good customer service team made you fell welcome on the flight.

Related info for your journey

How long is the flight from Guatemala City to San Francisco?
There are many flights that can get you from Guatemala City to San Francisco in 9h 30m. Fly via United Airlines to get the fastest option. There are 2514 mi between Guatemala City and San Francisco.
What are the cheapest airlines flying from Guatemala City to San Francisco round-trip?
Our cheapest airline available from Guatemala City to San Francisco is Avianca. Our recent data shows that you can find tickets from as low as $266 on this airline. Additional options worth looking into are United Airlines and American Airlines, starting at $289 and $361 round-trip. Users have found that Avianca is 35% cheaper than the other options available to this destination.
What are the cheapest airlines to fly from Guatemala City to San Francisco one-way?
The cheapest airlines for a one-way flight from Guatemala City to San Francisco are Volaris El Salvador ($135), American Airlines ($157), and Avianca ($159).
What are the cheapest flights from Guatemala City to San Francisco?
The cheapest flight price from Guatemala City to San Francisco is $255. On average you can expect to pay $565. The most popular route, (Guatemala City La Aurora - San Francisco), can usually be booked for $380.
Where are the most common layover locations when flying from Guatemala City to San Francisco?
Most of the time, Guatemala City to San Francisco flights that have layovers will stop in San Salvador. San Salvador is followed by Houston in terms of the most popular layover location on flights from Guatemala City to San Francisco.
What are some popular points of interest to see during a layover in Houston?
The majority of Houston visitors spend their time at Space Center Houston, House of Blues Houston, and Bayou Music Center. Space Center Houston, House of Blues Houston, and Bayou Music Center are located about 33.5 mi, 16.1 mi, and 15.5 mi, respectively from Houston George Bush Intcntl. Travelers can rent a car at Houston George Bush Intcntl for an average daily rate of $41 to make sightseeing during their layover a little easier.
Where are the least popular layover locations for Guatemala City to San Francisco flights?
Guatemala City to San Francisco flights that have layovers will least frequently stop in Los Angeles.
Can I find deals for flights from Guatemala City to San Francisco that include hotel bookings?
Yes. In addition to deals on Guatemala City to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Guatemala City to San Francisco?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Guatemala City to San Francisco.
Can I find deals for business class flights from Guatemala City to San Francisco?
Yes. Cheapflights offers flight deals from Guatemala City to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Guatemala City to San Francisco?
Currently, February is the cheapest month in which you can book a flight from Guatemala City to San Francisco (average of $332). Flying from Guatemala City to San Francisco in March is currently the most expensive (average of $486). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Top 4 airlines flying from Guatemala City to San Francisco

Airline	Cheapest	Average	Flexibility	On-time
Avianca	Cheapest$266	Average$469	FlexibilityNo cancel fee	On-time71%
United Airlines	Cheapest$289	Average$427	FlexibilityNo cancel fee	On-time69%
American Airlines	Cheapest$361	Average$534	FlexibilityNo cancel fee	On-time71%
Alaska Airlines	Cheapest$369	Average$621	FlexibilityNo cancel fee	On-time75%

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$216+ Cheap flights from Guatemala City (GUA) to San Francisco (SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/11. Fares are subject to change and may not be available on all flights or dates of travel.

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Cheapest flights from Guatemala City to San FranciscoExplore the most affordable flight options available from Guatemala City to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 28, 2026.

Explore the most affordable flight options available from Guatemala City to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 28, 2026.

Best flights from Guatemala City to San FranciscoDiscover carefully curated flight deals from Guatemala City to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 28, 2026.

Discover carefully curated flight deals from Guatemala City to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 28, 2026.

Last-minute flights from Guatemala City to San FranciscoDiscover last-minute flight deals from Guatemala City to San Francisco. Data last updated April 28, 2026 and is based on user searches.

Discover last-minute flight deals from Guatemala City to San Francisco. Data last updated April 28, 2026 and is based on user searches.

One-way flights from Guatemala City to San FranciscoSearch for one-way flight options from Guatemala City to San Francisco. Find affordable one-way fares based on user searches. Data last updated April 28, 2026.

Search for one-way flight options from Guatemala City to San Francisco. Find affordable one-way fares based on user searches. Data last updated April 28, 2026.

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Everything you need to know about your flight from Guatemala City to San Francisco

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Guatemala City and San Francisco flights

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Top 4 airlines flying from Guatemala City to San Francisco

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Cheapest flights from Guatemala City to San Francisco
Explore the most affordable flight options available from Guatemala City to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 28, 2026.

Best flights from Guatemala City to San Francisco
Discover carefully curated flight deals from Guatemala City to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 28, 2026.

Last-minute flights from Guatemala City to San Francisco
Discover last-minute flight deals from Guatemala City to San Francisco. Data last updated April 28, 2026 and is based on user searches.

One-way flights from Guatemala City to San Francisco
Search for one-way flight options from Guatemala City to San Francisco. Find affordable one-way fares based on user searches. Data last updated April 28, 2026.