$345+ Cheap flights from San Francisco (SFO) to Panama City (PTY)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/12. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — PTY
Nov 22 — Nov 291
Round-trip
1 adult, Economy
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Find cheap flights from San Francisco to Panama City with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from San Francisco to Panama City Tocumen Intl are usually found in April or May, booked 20 days in advance, depart on a Wednesday or Tuesday and return on a Wednesday
Cheap flight deals from San Francisco to Panama City
Cheapest
Best
Last-minute
One-way
Cheapest flights from San Francisco to Panama CityExplore the most affordable flight options available from San Francisco to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 23, 2026.
Explore the most affordable flight options available from San Francisco to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 23, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/58:32 pm -
2 stops38h 14m
Sat 12/1212:40 pm -
Nonstop7h 45m
Deal found 10/18![Multiple Airlines logo]()
$806
This Avianca deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/151:15 pm -
1 stop9h 55m
Mon 11/235:30 am -
1 stop19h 10m
Deal found 10/20![Avianca logo]()
$810
This Avianca deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/31:15 pm -
1 stop9h 55m
Mon 12/75:30 am -
1 stop9h 25m
Deal found 10/20![Avianca logo]()
$819
This Kiwi.com deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/58:32 pm -
2 stops38h 14m
Wed 12/912:40 pm -
Nonstop7h 45m
Deal found 10/22![Multiple Airlines logo]()
$830
This Justfly.com deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/61:15 pm -
1 stop9h 55m
Wed 11/115:30 am -
1 stop9h 25m
Deal found 10/19![Avianca logo]()
$832
This Kiwi.com deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/222:15 pm -
1 stop9h 40m
Mon 10/265:30 am -
1 stop9h 25m
Deal found 10/22![Avianca logo]()
$836
This FlightHub deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/301:15 pm -
1 stop9h 55m
Mon 12/75:30 am -
1 stop9h 25m
Deal found 10/22![Avianca logo]()
$842
This Kiwi.com deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/44:29 pm -
1 stop12h 11m
Fri 12/111:45 pm -
1 stop10h 35m
Deal found 10/22![Multiple Airlines logo]()
$844
This Kiwi.com deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/58:32 pm -
2 stops30h 30m
Thu 12/106:31 pm -
Nonstop7h 46m
Deal found 10/22![Multiple Airlines logo]()
$845
This Kiwi.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/59:31 pm -
3 stops37h 15m
Tue 12/812:40 pm -
Nonstop7h 45m
Deal found 10/21![Multiple Airlines logo]()
$848
This Justfly.com deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/71:30 am -
1 stop21h 40m
Tue 11/105:30 am -
1 stop9h 25m
Deal found 10/19![Avianca logo]()
$849
Best flights from San Francisco to Panama CityDiscover carefully curated flight deals from San Francisco to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 23, 2026.
Discover carefully curated flight deals from San Francisco to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 23, 2026.
This Copa Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/1712:40 am -
Nonstop7h 06m
Wed 1/2712:40 pm -
Nonstop7h 45m
Deal found 10/18![Copa Airlines logo]()
$856
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/117:15 am -
1 stop9h 23m
Sat 1/164:41 pm -
1 stop10h 49m
Deal found 10/22![United Airlines logo]()
$862
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/296:05 am -
1 stop12h 40m
Fri 1/88:00 am -
2 stops20h 20m
Deal found 10/21![Delta logo]()
$876
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/157:15 am -
1 stop9h 23m
Thu 1/2111:35 am -
1 stop12h 36m
Deal found 10/22![United Airlines logo]()
$862
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/146:36 pm -
1 stop22h 02m
Mon 1/188:55 am -
1 stop18h 35m
Deal found 10/22![United Airlines logo]()
$862
This United Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/96:36 pm -
1 stop19h 36m
Sat 1/164:41 pm -
1 stop10h 49m
Deal found 10/18![United Airlines logo]()
$871
This United Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/136:36 pm -
1 stop19h 36m
Tue 1/198:55 am -
1 stop14h 14m
Deal found 10/19![United Airlines logo]()
$871
This United Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/1011:45 pm -
1 stop12h 00m
Sat 1/164:41 pm -
1 stop10h 49m
Deal found 10/18![United Airlines logo]()
$871
This United Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/164:40 pm -
1 stop19h 05m
Thu 1/2111:35 am -
1 stop13h 55m
Deal found 10/18![United Airlines logo]()
$871
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/187:15 am -
1 stop9h 23m
Mon 2/154:41 pm -
1 stop19h 54m
Deal found 10/20![United Airlines logo]()
$871
This United Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/311:59 pm -
1 stop11h 46m
Thu 12/104:41 pm -
1 stop11h 04m
Deal found 10/19![United Airlines logo]()
$886
Last-minute flights from San Francisco to Panama CityDiscover last-minute flight deals from San Francisco to Panama City. Data last updated October 23, 2026 and is based on user searches.
Discover last-minute flight deals from San Francisco to Panama City. Data last updated October 23, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/222:15 pm -
1 stop9h 40m
Mon 10/265:30 am -
1 stop9h 25m
Deal found 10/22![Avianca logo]()
$836
This Avianca deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/51:15 pm -
1 stop9h 55m
Sat 11/145:30 am -
1 stop9h 25m
Deal found 10/19![Avianca logo]()
$857
This Avianca deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/51:15 pm -
1 stop9h 55m
Tue 11/1010:05 am -
2 stops14h 35m
Deal found 10/19![Avianca logo]()
$869
This Justfly.com deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/61:15 pm -
1 stop9h 55m
Wed 11/115:30 am -
1 stop9h 25m
Deal found 10/19![Avianca logo]()
$832
This Mytrip deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/61:15 pm -
2 stops47h 00m
Tue 11/1010:05 am -
2 stops28h 50m
Deal found 10/21![Avianca logo]()
$861
This Justfly.com deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/71:30 am -
1 stop21h 40m
Tue 11/105:30 am -
1 stop9h 25m
Deal found 10/19![Avianca logo]()
$849
This FlightHub deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/71:30 am -
1 stop21h 40m
Fri 11/135:30 am -
1 stop19h 10m
Deal found 10/20![Avianca logo]()
$859
This Avianca deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/151:15 pm -
1 stop9h 55m
Mon 11/235:30 am -
1 stop19h 10m
Deal found 10/20![Avianca logo]()
$810
This Avianca deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/291:15 pm -
1 stop9h 55m
Fri 12/410:05 am -
2 stops14h 35m
Deal found 10/19![Avianca logo]()
$873
This FlightHub deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/301:15 pm -
1 stop9h 55m
Tue 12/85:30 am -
1 stop9h 25m
Deal found 10/22![Avianca logo]()
$842
This Avianca deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/301:15 pm -
1 stop9h 55m
Sun 12/65:30 am -
1 stop9h 25m
Deal found 10/22![Avianca logo]()
$867
One-way flights from San Francisco to Panama CitySearch for one-way flight options from San Francisco to Panama City. Find affordable one-way fares based on user searches. Data last updated October 23, 2026.
Search for one-way flight options from San Francisco to Panama City. Find affordable one-way fares based on user searches. Data last updated October 23, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/126:30 pm -
3 stops42h 31m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/22![Multiple Airlines logo]()
$345
This Kiwi.com deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/910:29 am -
2 stops24h 17m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![Multiple Airlines logo]()
$354
This Kiwi.com deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/1111:06 am -
3 stops29h 39m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/22![Multiple Airlines logo]()
$359
This Kiwi.com deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/139:44 am -
3 stops27h 17m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/22![Multiple Airlines logo]()
$365
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/810:29 am -
2 stops24h 17m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![Multiple Airlines logo]()
$366
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/74:21 pm -
2 stops42h 12m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![Multiple Airlines logo]()
$379
This Kiwi.com deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/68:48 pm -
2 stops37h 58m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/22![Multiple Airlines logo]()
$391
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/306:00 pm -
3 stops40h 33m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![Multiple Airlines logo]()
$395
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/315:39 pm -
2 stops16h 54m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![Multiple Airlines logo]()
$398
Find flight deals from San Francisco to Panama City
Discover tips and strategies to find the most affordable flight options for your journey from San Francisco (SFO) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 23, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $806 (Kiwi.com) |
One-way from | $345 (Kiwi.com) |
Popular in | December |
Cheapest in | April |
Average price | $831 |
Good round-trip deal | $790 or less |
Good one-way deal | $537 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from San Francisco to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 23, 2026.
Use the filters below to find and compare flights from San Francisco to Panama City that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San FranciscoPanama City
SFO San Francisco - PTY Panama City Tocumen Intl
SFOPTY
San Francisco
Mon 12/28
9:59 pm-6:00 pm
3 stops41h 01m
Panama City Tocumen Intl
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$507
San FranciscoPanama City
SFO San Francisco - PTY Panama City Tocumen Intl
SFOPTY
San Francisco
Mon 1/18
12:00 pm-5:03 pm
2 stops26h 03m
Panama City Tocumen Intl
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$525
San FranciscoPanama City
SFO San Francisco - PTY Panama City Tocumen Intl
SFOPTY
San Francisco
Fri 12/18
9:23 pm-2:01 pm
2 stops37h 38m
Panama City Tocumen Intl
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$707
San FranciscoPanama City
SFO San Francisco - PTY Panama City Tocumen Intl
SFOPTY
San Francisco
Thu 12/3
4:27 pm-2:45 pm
1 stop19h 18m
Panama City Tocumen Intl
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$786
San FranciscoPanama City
SFO San Francisco - PTY Panama City Tocumen Intl
SFOPTY
San Francisco
Wed 11/4
6:42 pm-2:45 pm
1 stop17h 03m
Panama City Tocumen Intl
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$795
San FranciscoPanama City
SFO San Francisco - PTY Panama City Tocumen Intl
SFOPTY
San Francisco
Tue 12/22
5:00 am-7:38 pm
1 stop11h 38m
Panama City Tocumen Intl
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$795
San FranciscoPanama City
SFO San Francisco - PTY Panama City Tocumen Intl
SFOPTY
San Francisco
Tue 11/3
4:40 pm-2:45 pm
1 stop19h 05m
Panama City Tocumen Intl
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$795
San FranciscoPanama City
SFO San Francisco - PTY Panama City Tocumen Intl
SFOPTY
San Francisco
Thu 12/17
6:35 pm-2:45 pm
1 stop17h 10m
Panama City Tocumen Intl
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$820
San FranciscoPanama City
SFO San Francisco - PTY Panama City Tocumen Intl
SFOPTY
San Francisco
Sun 1/17
12:40 am-10:46 am
Nonstop7h 06m
Panama City Tocumen Intl
Wed 1/27
12:40 pm-5:25 pm
Nonstop7h 45m
$856
San FranciscoPanama City
SFO San Francisco - PTY Panama City Tocumen Intl
SFOPTY
San Francisco
Mon 1/11
7:15 am-7:38 pm
1 stop9h 23m
Panama City Tocumen Intl
Sat 1/16
4:41 pm-12:30 am
1 stop10h 49m
$862
Showing 1-10 of 22 resultsSorted by cheapest first
Compare providers for flights from San Francisco to Panama City
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Francisco to Panama City in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*1 star | |
| Price Accuracy3 stars | Trust Score*1 star | |
| Price Accuracy- | Trust Score*1 star | |
| Price Accuracy- | Trust Score*1 star |
- Most accurate provider: When it comes to deals on San Francisco-Panama City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Francisco-Panama City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Francisco-Panama City flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on San Francisco-Panama City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Francisco-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from San Francisco to Panama City
Have a flexible travel schedule? Discover the best time to fly to Panama City from San Francisco with our price prediction graph.
SFO-PTY
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Francisco to Panama City
Prices
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How far ahead should I book a flight from San Francisco to Panama City?
The best time to book flights from San Francisco to Panama City is 19 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
What is the cheapest month to book a flight from San Francisco to Panama City?
Currently, April is the cheapest month in which you can book a flight from San Francisco to Panama City (average of $674). Flying from San Francisco to Panama City in December is currently the most expensive (average of $1,030). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from SFO to PTY?
Find hourly flight availability from San Francisco to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 23, 2026.
When flying from San Francisco to Panama City, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
How often are flights from San Francisco to Panama City delayed?
About 7% of weekly flights between San Francisco and Panama City have experienced delays in the past year, with the average delay time being 105 minutes.
What is the most punctual flight time for San Francisco to Panama City flights?
Historically, flights departing at night are less likely to be delayed, whereas flights leaving in the morning tend to experience delays more often.
What day of the week experiences the fewest flight delays on this route?
Monday tends to have the lowest number of delays on this route, whereas Tuesday has historically faced a higher average of delays compared to other days of the week.
Which airline has the best punctuality record on San Francisco to Panama City flights?
Over the last year, Copa Airlines have had the lowest number of delays on this route, with just 6% of flights being delayed.
What’s the top layover airport for flights from San Francisco to Panama City?
Share of 1-stop round-trip flights from San Francisco to Panama City chosen by Cheapflights users in the past 12 months, using the same layover each way.
Orlando (MCO) – chosen by Cheapflights users on 67% of 1-stop itineraries from San Francisco to Panama City on Cheapflights.
What’s the cheapest layover airport for flights from San Francisco to Panama City?
Average round-trip fare for 1-stop flights from San Francisco to Panama City, chosen by Cheapflights users in the past 12 months, with the same layover each way.
San Salvador (SAL) is the most affordable 1-stop option, with an average round-trip price of $923.
What’s the fastest layover option from San Francisco to Panama City?
Shortest average travel time for 1-stop one-way flights from San Francisco to Panama City, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.
Flights via San Salvador (SAL) have the shortest average one-way travel time for 1-stop routes: 8h 20m.
Which airport typically offers the quickest layover for flights from San Francisco to Panama City?
Average layover duration for 1-stop one-way flights from San Francisco to Panama City, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.
Flights via San Salvador (SAL) offer the fastest connection on this route, with an average layover time of 1h 13m.
The best insider tips for San Francisco to Panama City flights
AI-powered summary based on content written by travel experts. AI can make mistakes.
Cheapflights partnered with top experts to bring you the best recommendations for your San Francisco to Panama City trip
Our travel experts
Reviews of airlines servicing Panama City
Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated October 23, 2026.
Read reviews from past customers who have flown Copa Airlines,United Airlines, andAvianca from San Francisco to Panama City. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.5
Food
7.0
Boarding
7.8
Entertainment
6.9
Overall
7.6
Crew
8.1
Reviews
1 / 20
2.0
MediocreAnonymous,Oct 2026
BOS - PTY
Comfort
7.5
Food
7.0
Boarding
7.8
Entertainment
6.9
Overall
7.6
Crew
8.1
Reviews
1 / 20
2.0
MediocreAnonymous,Oct 2026
BOS - PTY
Comfort
7.5
Food
7.0
Boarding
7.8
Entertainment
6.9
Overall
7.6
Crew
8.1
Reviews
1 / 20
2.0
MediocreAnonymous,Oct 2026
BOS - PTY
Comfort
7.5
Food
7.0
Boarding
7.8
Entertainment
6.9
Overall
7.6
Crew
8.1
Reviews
1 / 20
2.0
MediocreAnonymous,Oct 2026
BOS - PTY
Related info for your journey
Find useful and relevant information for your journey from San Francisco to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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San Francisco and Panama City flights
Browse other San Francisco and Panama City flight options. Last updated on October 23, 2026.
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Top 3 airlines flying from San Francisco to Panama City
Discover the top 3 airlines that operate flights from San Francisco to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 23, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$227 | Average$578 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$499 | Average$814 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$614 | Average$903 | FlexibilityNo cancel fee | On-time69% |