$243+ Cheap flights from San Francisco (SFO) to Panama City (PTY)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/15. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — PTY
May 22 — May 291
Round-trip
1 adult, Economy
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Find cheap flights from San Francisco to Panama City with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from San Francisco to Panama City Tocumen Intl are usually found in October or August, booked 49 days in advance, depart on a Monday or Tuesday and return on a Saturday
Cheap flight deals from San Francisco to Panama City
Cheapest
Best
Last-minute
One-way
Cheapest flights from San Francisco to Panama CityExplore the most affordable flight options available from San Francisco to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 22, 2026.
Explore the most affordable flight options available from San Francisco to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 22, 2026.
This oojo deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/1611:55 pm
SFO
- PTY
1 stop8h 35m
Avianca
Sun 5/245:30 am
PTY
- SFO
1 stop9h 20m
Avianca
Deal found 4/21![Avianca logo]()
$585
This oojo deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2211:55 pm
SFO
- PTY
1 stop8h 35m
Avianca
Sun 5/34:25 am
PTY
- SFO
2 stops34h 25m
Avianca
Deal found 4/17![Avianca logo]()
$590
This oojo deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/212:15 pm
SFO
- PTY
2 stops17h 00m
Avianca
Sun 5/315:55 pm
PTY
- SFO
2 stops30h 40m
Avianca
Deal found 4/21![Avianca logo]()
$595
This oojo deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/222:15 pm
SFO
- PTY
1 stop18h 15m
Avianca
Mon 5/253:10 pm
PTY
- SFO
2 stops33h 25m
Avianca
Deal found 4/20![Avianca logo]()
$600
This oojo deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2711:55 pm
SFO
- PTY
1 stop24h 00m
Avianca
Fri 5/15:30 am
PTY
- SFO
1 stop9h 20m
Avianca
Deal found 4/17![Avianca logo]()
$602
This Avianca deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/242:15 pm
SFO
- PTY
2 stops17h 00m
Avianca
Sat 5/210:10 am
PTY
- SFO
2 stops15h 45m
Avianca
Deal found 4/20![Avianca logo]()
$605
This Avianca deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/1811:55 pm
SFO
- PTY
1 stop8h 35m
Avianca
Tue 5/2610:10 am
PTY
- SFO
2 stops14h 25m
Avianca
Deal found 4/17![Avianca logo]()
$606
This Avianca deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1911:55 pm
SFO
- PTY
1 stop8h 35m
Avianca
Tue 5/2610:10 am
PTY
- SFO
2 stops14h 25m
Avianca
Deal found 4/19![Avianca logo]()
$607
This oojo deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/277:45 am
SFO
- PTY
2 stops16h 10m
Avianca
Mon 8/35:55 pm
PTY
- SFO
2 stops32h 00m
Avianca
Deal found 4/19![Avianca logo]()
$610
This Avianca deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/17:45 am
SFO
- PTY
2 stops16h 10m
Avianca
Mon 8/315:30 am
PTY
- SFO
1 stop19h 05m
Avianca
Deal found 4/20![Avianca logo]()
$614
This Avianca deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/112:15 pm
SFO
- PTY
2 stops17h 00m
Avianca
Sun 7/1210:10 am
PTY
- SFO
2 stops14h 25m
Avianca
Deal found 4/21![Avianca logo]()
$615
Best flights from San Francisco to Panama CityDiscover carefully curated flight deals from San Francisco to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 22, 2026.
Discover carefully curated flight deals from San Francisco to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 22, 2026.
This Avianca deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/182:15 pm
SFO
- PTY
2 stops17h 00m
Avianca
Tue 5/2610:10 am
PTY
- SFO
2 stops14h 25m
Avianca
Deal found 4/19![Avianca logo]()
$605
This Copa Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/131:12 am
SFO
- PTY
Nonstop7h 15m
Copa Airlines
Thu 9/246:08 pm
PTY
- SFO
Nonstop7h 32m
Copa Airlines
Deal found 4/17![Copa Airlines logo]()
$696
This United Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/136:54 pm
SFO
- PTY
1 stop19h 18m
United Airlines
Tue 6/233:30 pm
PTY
- SFO
1 stop10h 45m
United Airlines
Deal found 4/20![United Airlines logo]()
$711
This United Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1811:59 pm
SFO
- PTY
1 stop12h 15m
United Airlines
Wed 10/283:41 pm
PTY
- SFO
1 stop19h 44m
United Airlines
Deal found 4/20![United Airlines logo]()
$711
This Copa Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/251:12 am
SFO
- PTY
Nonstop7h 15m
Copa Airlines
Tue 6/25:55 pm
PTY
- SFO
Nonstop7h 45m
Copa Airlines
Deal found 4/17![Copa Airlines logo]()
$726
This United Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/1912:45 am
SFO
- PTY
1 stop15h 52m
United Airlines
Tue 9/83:30 pm
PTY
- SFO
1 stop10h 46m
United Airlines
Deal found 4/21![United Airlines logo]()
$711
This Copa Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/251:12 am
SFO
- PTY
Nonstop7h 15m
Copa Airlines
Tue 6/95:55 pm
PTY
- SFO
Nonstop7h 45m
Copa Airlines
Deal found 4/17![Copa Airlines logo]()
$741
This Copa Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/248:16 pm
SFO
- PTY
Nonstop7h 19m
Copa Airlines
Fri 5/295:55 pm
PTY
- SFO
Nonstop7h 45m
Copa Airlines
Deal found 4/20![Copa Airlines logo]()
$741
This Copa Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/281:12 am
SFO
- PTY
Nonstop7h 15m
Copa Airlines
Mon 6/85:55 pm
PTY
- SFO
Nonstop7h 45m
Copa Airlines
Deal found 4/22![Copa Airlines logo]()
$741
This Copa Airlines deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/151:12 am
SFO
- PTY
Nonstop7h 15m
Copa Airlines
Sat 5/2312:38 pm
PTY
- SFO
Nonstop7h 36m
Copa Airlines
Deal found 4/18![Copa Airlines logo]()
$792
This Copa Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/68:16 pm
SFO
- PTY
Nonstop7h 19m
Copa Airlines
Sat 6/205:55 pm
PTY
- SFO
Nonstop7h 45m
Copa Airlines
Deal found 4/20![Copa Airlines logo]()
$792
Last-minute flights from San Francisco to Panama CityDiscover last-minute flight deals from San Francisco to Panama City. Data last updated April 22, 2026 and is based on user searches.
Discover last-minute flight deals from San Francisco to Panama City. Data last updated April 22, 2026 and is based on user searches.
This oojo deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2211:55 pm
SFO
- PTY
1 stop8h 35m
Avianca
Wed 4/2910:10 am
PTY
- SFO
2 stops14h 25m
Avianca
Deal found 4/17![Avianca logo]()
$590
This Avianca deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/242:15 pm
SFO
- PTY
2 stops17h 00m
Avianca
Sat 5/210:10 am
PTY
- SFO
2 stops15h 45m
Avianca
Deal found 4/20![Avianca logo]()
$605
This oojo deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2711:55 pm
SFO
- PTY
1 stop24h 00m
Avianca
Fri 5/15:30 am
PTY
- SFO
1 stop9h 20m
Avianca
Deal found 4/21![Avianca logo]()
$602
This oojo deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/12:15 pm
SFO
- PTY
1 stop9h 40m
Avianca
Sun 5/313:10 pm
PTY
- SFO
3 stops41h 15m
Avianca
Deal found 4/20![Avianca logo]()
$617
This Avianca deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/112:15 pm
SFO
- PTY
2 stops17h 00m
Avianca
Sun 7/1210:10 am
PTY
- SFO
2 stops14h 25m
Avianca
Deal found 4/21![Avianca logo]()
$615
This oojo deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/1611:55 pm
SFO
- PTY
1 stop8h 35m
Avianca
Sat 5/233:50 pm
PTY
- SFO
1 stop10h 05m
Avianca
Deal found 4/20![Avianca logo]()
$585
This Avianca deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/1811:55 pm
SFO
- PTY
1 stop8h 35m
Avianca
Tue 5/2610:10 am
PTY
- SFO
2 stops14h 25m
Avianca
Deal found 4/17![Avianca logo]()
$606
This Avianca deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1911:55 pm
SFO
- PTY
1 stop8h 35m
Avianca
Tue 5/2610:10 am
PTY
- SFO
2 stops14h 25m
Avianca
Deal found 4/19![Avianca logo]()
$607
This oojo deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/212:15 pm
SFO
- PTY
2 stops17h 00m
Avianca
Sun 5/315:55 pm
PTY
- SFO
2 stops30h 40m
Avianca
Deal found 4/21![Avianca logo]()
$595
This oojo deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/222:15 pm
SFO
- PTY
1 stop18h 15m
Avianca
Mon 5/253:10 pm
PTY
- SFO
2 stops33h 25m
Avianca
Deal found 4/20![Avianca logo]()
$600
One-way flights from San Francisco to Panama CitySearch for one-way flight options from San Francisco to Panama City. Find affordable one-way fares based on user searches. Data last updated April 22, 2026.
Search for one-way flight options from San Francisco to Panama City. Find affordable one-way fares based on user searches. Data last updated April 22, 2026.
This oojo deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/157:45 am
SFO
- PTY
2 stops16h 10m
Avianca
Deal found 4/22![Avianca logo]()
$243
This oojo deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/272:15 pm
SFO
- PTY
2 stops17h 00m
Avianca
Deal found 4/19![Avianca logo]()
$248
This oojo deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/287:45 am
SFO
- PTY
2 stops16h 10m
Avianca
Deal found 4/20![Avianca logo]()
$253
This oojo deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/92:30 am
SFO
- PTY
1 stop21h 25m
Avianca
Deal found 4/19![Avianca logo]()
$270
This Avianca deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1211:55 pm
SFO
- PTY
1 stop8h 35m
Avianca
Deal found 4/20![Avianca logo]()
$272
This Avianca deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/611:55 pm
SFO
- PTY
1 stop8h 35m
Avianca
Deal found 4/20![Avianca logo]()
$273
This Trip.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/511:55 pm
SFO
- PTY
1 stop8h 35m
Avianca
Deal found 4/20![Avianca logo]()
$274
This oojo deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/167:45 am
SFO
- PTY
3 stops31h 15m
Avianca
Deal found 4/19![Avianca logo]()
$275
This Super.com deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/87:45 am
SFO
- PTY
1 stop16h 10m
Avianca
Deal found 4/22![Avianca logo]()
$277
This Kiwi.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/1111:55 pm
SFO
- PTY
1 stop8h 35m
Avianca
Deal found 4/20![Avianca logo]()
$283
Find flight deals from San Francisco to Panama City
Discover tips and strategies to find the most affordable flight options for your journey from San Francisco (SFO) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 22, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $585 (oojo) |
One-way from | $243 (oojo) |
Popular in | December |
Cheapest in | October |
Average price | $668 |
Good round-trip deal | $604 or less |
Good one-way deal | $303 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from San Francisco to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 22, 2026.
Use the filters below to find and compare flights from San Francisco to Panama City that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San FranciscoPanama City
SFO - PTY
SFOPTY
San Francisco
Mon 5/18
2:15 pm-9:15 am
2 stops17h 00m
Panama City Tocumen Intl
Tue 5/26
10:10 am-10:35 pm
2 stops14h 25m
$605
Quickest round-trip
San FranciscoPanama City
SFO - PTY
SFOPTY
San Francisco
Sun 9/13
1:12 am-10:27 am
Nonstop7h 15m
Panama City Tocumen Intl
Thu 9/24
6:08 pm-11:40 pm
Nonstop7h 32m
$696
San FranciscoPanama City
SFO - PTY
SFOPTY
San Francisco
Sat 6/13
6:54 pm-4:12 pm
1 stop19h 18m
Panama City Tocumen Intl
Tue 6/23
3:30 pm-12:15 am
1 stop10h 45m
$711
San FranciscoPanama City
SFO - PTY
SFOPTY
San Francisco
Tue 8/18
11:59 pm-2:14 pm
1 stop12h 15m
Panama City Tocumen Intl
Wed 10/28
3:41 pm-9:25 am
1 stop19h 44m
$711
San FranciscoPanama City
SFO - PTY
SFOPTY
San Francisco
Sun 7/19
12:45 am-6:37 pm
1 stop15h 52m
Panama City Tocumen Intl
Tue 9/8
3:30 pm-12:16 am
1 stop10h 46m
$711
San FranciscoPanama City
SFO - PTY
SFOPTY
San Francisco
Mon 5/25
1:12 am-10:27 am
Nonstop7h 15m
Panama City Tocumen Intl
Tue 6/2
5:55 pm-11:40 pm
Nonstop7h 45m
$726
San FranciscoPanama City
SFO - PTY
SFOPTY
San Francisco
Mon 5/25
1:12 am-10:27 am
Nonstop7h 15m
Panama City Tocumen Intl
Tue 6/9
5:55 pm-11:40 pm
Nonstop7h 45m
$741
San FranciscoPanama City
SFO - PTY
SFOPTY
San Francisco
Sun 5/24
8:16 pm-5:35 am
Nonstop7h 19m
Panama City Tocumen Intl
Fri 5/29
5:55 pm-11:40 pm
Nonstop7h 45m
$741
San FranciscoPanama City
SFO - PTY
SFOPTY
San Francisco
Thu 5/28
1:12 am-10:27 am
Nonstop7h 15m
Panama City Tocumen Intl
Mon 6/8
5:55 pm-11:40 pm
Nonstop7h 45m
$741
San FranciscoPanama City
SFO - PTY
SFOPTY
San Francisco
Fri 5/15
1:12 am-10:27 am
Nonstop7h 15m
Panama City Tocumen Intl
Sat 5/23
12:38 pm-6:14 pm
Nonstop7h 36m
$792
Showing 1-10 of 21 resultsSorted by cheapest first
Compare providers for flights from San Francisco to Panama City
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Francisco to Panama City in April.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*2 stars | |
| Price Accuracy2 stars | Trust Score*2 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star | |
| Price Accuracy- | Trust Score*1 star |
- Most accurate provider: When it comes to deals on San Francisco-Panama City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Francisco-Panama City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Francisco-Panama City flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on San Francisco-Panama City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Francisco-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from San Francisco to Panama City
Have a flexible travel schedule? Discover the best time to fly to Panama City from San Francisco with our price prediction graph.
SFO-PTY
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Francisco to Panama City
Prices
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How far ahead should I book a flight from San Francisco to Panama City?
Use this chart to determine the optimal time to book a round-trip flight from San Francisco to Panama City. Price data was last updated on April 17, 2026.
The best time to book flights from San Francisco to Panama City is 49 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
What is the cheapest month to book a flight from San Francisco to Panama City?
Currently, October is the cheapest month in which you can book a flight from San Francisco to Panama City (average of $533). Flying from San Francisco to Panama City in December is currently the most expensive (average of $840). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from SFO to PTY?
Find hourly flight availability from San Francisco to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 22, 2026.
When flying from San Francisco to Panama City, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
How often are flights from San Francisco to Panama City delayed?
About 8% of weekly flights between San Francisco and Panama City have experienced delays in the past year, with the average delay time being 124 minutes.
What is the most punctual flight time for San Francisco to Panama City flights?
Historically, flights departing at night are less likely to be delayed, whereas flights leaving in the morning tend to experience delays more often.
What day of the week experiences the fewest flight delays on this route?
Monday tends to have the lowest number of delays on this route, whereas Thursday has historically faced a higher average of delays compared to other days of the week.
Which airline has the best punctuality record on San Francisco to Panama City flights?
Over the last year, Copa Airlines have had the lowest number of delays on this route, with just 5% of flights being delayed.
What’s the top layover airport for flights from San Francisco to Panama City?
Share of 1-stop round-trip flights from San Francisco to Panama City chosen by Cheapflights users in the past 12 months, using the same layover each way.
San Salvador (SAL) – chosen by Cheapflights users on 67% of 1-stop itineraries from San Francisco to Panama City on Cheapflights.
What’s the cheapest layover airport for flights from San Francisco to Panama City?
Average round-trip fare for 1-stop flights from San Francisco to Panama City, chosen by Cheapflights users in the past 12 months, with the same layover each way.
San Salvador (SAL) is the most affordable 1-stop option, with an average round-trip price of $592.
What’s the fastest layover option from San Francisco to Panama City?
Shortest average travel time for 1-stop one-way flights from San Francisco to Panama City, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.
Flights via San Salvador (SAL) have the shortest average one-way travel time for 1-stop routes: 8h 20m.
Which airport typically offers the quickest layover for flights from San Francisco to Panama City?
Average layover duration for 1-stop one-way flights from San Francisco to Panama City, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.
Flights via San Salvador (SAL) offer the fastest connection on this route, with an average layover time of 1h 05m.
The best insider tips for San Francisco to Panama City flights
AI-powered summary based on content written by travel experts. AI can make mistakes.
Cheapflights partnered with top experts to bring you the best recommendations for your San Francisco to Panama City trip
Our travel experts
Reviews of airlines servicing Panama City
Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated April 22, 2026.
Read reviews from past customers who have flown Delta,Copa Airlines, andUnited Airlines from San Francisco to Panama City. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.9
Crew
8.5
Boarding
8.1
Entertainment
7.8
Food
7.2
Comfort
7.9
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Overall
7.9
Crew
8.5
Boarding
8.1
Entertainment
7.8
Food
7.2
Comfort
7.9
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Overall
7.9
Crew
8.5
Boarding
8.1
Entertainment
7.8
Food
7.2
Comfort
7.9
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Overall
7.9
Crew
8.5
Boarding
8.1
Entertainment
7.8
Food
7.2
Comfort
7.9
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Overall
7.9
Crew
8.5
Boarding
8.1
Entertainment
7.8
Food
7.2
Comfort
7.9
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Related info for your journey
Find useful and relevant information for your journey from San Francisco to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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San Francisco and Panama City flights
Browse other San Francisco and Panama City flight options. Last updated on April 22, 2026.
Other flights from San Francisco
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Explore flights to Panama City departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on April 22, 2026.
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Top 4 airlines flying from San Francisco to Panama City
Discover the top 4 airlines that operate flights from San Francisco to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 22, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$246 | Average$504 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$424 | Average$681 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$467 | Average$689 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$529 | Average$768 | FlexibilityNo cancel fee | On-time69% |