$331+ Cheap flights from San Francisco (SFO) to Panama
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/26. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — PTY
Aug 23 — Aug 301
Round-trip
1 adult, Economy
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Find cheap flights from San Francisco to Panama with Cheapflights
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Cheapest flights from San Francisco to PanamaExplore the most affordable flight options available from San Francisco to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 24, 2026.
Explore the most affordable flight options available from San Francisco to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 24, 2026.
This Booking.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2811:00 am
SFO
- PTY
2 stops19h 20m
Multiple Airlines
Sat 11/710:20 am
PTY
- SFO
1 stop27h 50m
Multiple Airlines
Deal found 7/23![Multiple Airlines logo]()
$704
This Kiwi.com deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/1310:48 pm
SFO
- PTY
2 stops31h 42m
Multiple Airlines
Mon 9/215:30 am
PTY
- SFO
1 stop9h 20m
Multiple Airlines
Deal found 7/20![Multiple Airlines logo]()
$746
This SmartFares deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/159:55 pm
SFO
- PTY
1 stop13h 03m
Delta
Wed 9/302:23 pm
PTY
- SFO
1 stop11h 34m
Delta
Deal found 7/20![Delta logo]()
$754
This Copa Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/218:21 pm
SFO
- PTY
Nonstop7h 14m
Copa Airlines
Mon 10/266:08 pm
PTY
- SFO
Nonstop7h 32m
Copa Airlines
Deal found 7/22![Copa Airlines logo]()
$776
This American Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/137:04 pm
SFO
- PTY
2 stops15h 12m
American Airlines
Mon 9/211:16 pm
PTY
- SFO
2 stops22h 36m
American Airlines
Deal found 7/20![American Airlines logo]()
$781
This United Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/197:05 am
SFO
- PTY
1 stop9h 32m
United Airlines
Thu 11/194:41 pm
PTY
- SFO
1 stop10h 58m
United Airlines
Deal found 7/23![United Airlines logo]()
$782
This Kiwi.com deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/97:17 pm
SFO
- PTY
2 stops18h 53m
Multiple Airlines
Sun 9/135:30 am
PTY
- SFO
1 stop9h 20m
Multiple Airlines
Deal found 7/19![Multiple Airlines logo]()
$784
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/191:07 pm
SFO
- PTY
1 stop15h 15m
Multiple Airlines
Sun 9/61:54 pm
PTY
- SFO
1 stop11h 18m
Multiple Airlines
Deal found 7/23![Multiple Airlines logo]()
$788
This Copa Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/211:12 am
SFO
- PTY
Nonstop7h 15m
Copa Airlines
Mon 10/266:08 pm
PTY
- SFO
Nonstop7h 32m
Copa Airlines
Deal found 7/22![Copa Airlines logo]()
$791
This United Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/37:05 am
SFO
- PTY
1 stop9h 32m
United Airlines
Thu 9/1010:00 am
PTY
- SFO
1 stop10h 29m
United Airlines
Deal found 7/20![United Airlines logo]()
$794
This American Airlines deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/242:58 pm
SFO
- PTY
2 stops19h 18m
American Airlines
Wed 10/141:52 pm
PTY
- SFO
2 stops21h 05m
American Airlines
Deal found 7/19![American Airlines logo]()
$795
This American Airlines deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1710:59 pm
SFO
- PTY
1 stop11h 53m
American Airlines
Sun 10/251:52 pm
PTY
- SFO
1 stop12h 07m
American Airlines
Deal found 7/19![American Airlines logo]()
$796
Best flights from San Francisco to PanamaDiscover carefully curated flight deals from San Francisco to Panama that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 24, 2026.
Discover carefully curated flight deals from San Francisco to Panama that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 24, 2026.
This Copa Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/1612:40 am
SFO
- PTY
Nonstop7h 06m
Copa Airlines
Sat 1/236:31 pm
PTY
- SFO
Nonstop7h 44m
Copa Airlines
Deal found 7/20![Copa Airlines logo]()
$776
This United Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/215:00 am
SFO
- PTY
1 stop11h 37m
United Airlines
Mon 10/267:55 am
PTY
- SFO
3 stops18h 41m
United Airlines
Deal found 7/21![United Airlines logo]()
$791
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/41:12 am
SFO
- DAV
1 stop16h 05m
Multiple Airlines
Sat 9/129:50 am
DAV
- SFO
2 stops13h 36m
Multiple Airlines
Deal found 7/22![Multiple Airlines logo]()
$1,295
This United Airlines deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1112:45 am
SFO
- PTY
1 stop15h 52m
United Airlines
Fri 10/163:30 pm
PTY
- SFO
1 stop10h 17m
United Airlines
Deal found 7/19![United Airlines logo]()
$791
This Copa Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/111:12 am
SFO
- PTY
Nonstop7h 15m
Copa Airlines
Sun 10/256:08 pm
PTY
- SFO
Nonstop7h 32m
Copa Airlines
Deal found 7/21![Copa Airlines logo]()
$791
This United Airlines deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/912:45 am
SFO
- PTY
1 stop13h 27m
United Airlines
Mon 12/148:55 am
PTY
- SFO
1 stop18h 09m
United Airlines
Deal found 7/19![United Airlines logo]()
$791
This Copa Airlines deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/248:21 pm
SFO
- PTY
Nonstop7h 14m
Copa Airlines
Wed 10/1412:38 pm
PTY
- SFO
Nonstop7h 32m
Copa Airlines
Deal found 7/19![Copa Airlines logo]()
$791
This United Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/612:45 am
SFO
- PTY
1 stop11h 00m
United Airlines
Mon 12/1411:35 am
PTY
- SFO
1 stop15h 29m
United Airlines
Deal found 7/21![United Airlines logo]()
$791
This Copa Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/912:33 am
SFO
- PTY
Nonstop7h 13m
Copa Airlines
Mon 12/146:31 pm
PTY
- SFO
Nonstop7h 46m
Copa Airlines
Deal found 7/23![Copa Airlines logo]()
$791
This United Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/911:59 pm
SFO
- PTY
1 stop16h 39m
United Airlines
Sat 1/1611:35 am
PTY
- SFO
1 stop14h 04m
United Airlines
Deal found 7/20![United Airlines logo]()
$791
This FlightHub deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1911:55 pm
SFO
- DAV
2 stops17h 22m
Multiple Airlines
Sun 10/258:43 am
DAV
- SFO
2 stops16h 07m
Multiple Airlines
Deal found 7/19![Multiple Airlines logo]()
$1,474
This Copa Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/41:12 am
SFO
- DAV
1 stop16h 05m
Copa Airlines
Sat 9/127:57 pm
DAV
- SFO
1 stop24h 13m
Copa Airlines
Deal found 7/22![Copa Airlines logo]()
$1,126
This Copa Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/198:21 pm
SFO
- DAV
1 stop10h 47m
Copa Airlines
Wed 8/269:50 am
DAV
- SFO
1 stop15h 50m
Copa Airlines
Deal found 7/20![Copa Airlines logo]()
$1,126
This United Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2111:59 pm
SFO
- DAV
2 stops31h 11m
United Airlines
Fri 9/259:50 am
DAV
- SFO
2 stops15h 57m
United Airlines
Deal found 7/23![United Airlines logo]()
$1,226
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/188:21 pm
SFO
- DAV
1 stop10h 47m
Copa Airlines
Sat 9/57:57 pm
DAV
- SFO
1 stop29h 43m
Copa Airlines
Deal found 7/23![Copa Airlines logo]()
$1,293
Last-minute flights from San Francisco to PanamaDiscover last-minute flight deals from San Francisco to Panama. Data last updated July 24, 2026 and is based on user searches.
Discover last-minute flight deals from San Francisco to Panama. Data last updated July 24, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/109:05 pm
SFO
- PTY
2 stops35h 36m
Multiple Airlines
Tue 8/185:30 am
PTY
- SFO
1 stop9h 20m
Multiple Airlines
Deal found 7/19![Multiple Airlines logo]()
$834
This Kiwi.com deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/148:23 pm
SFO
- PTY
2 stops15h 42m
Multiple Airlines
Tue 8/185:30 am
PTY
- SFO
1 stop9h 20m
Multiple Airlines
Deal found 7/19![Multiple Airlines logo]()
$847
This Copa Airlines deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/168:21 pm
SFO
- PTY
Nonstop7h 14m
Copa Airlines
Sun 8/2312:38 pm
PTY
- SFO
Nonstop7h 21m
Copa Airlines
Deal found 7/19![Copa Airlines logo]()
$824
This American Airlines deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/169:35 pm
SFO
- PTY
1 stop13h 04m
American Airlines
Sun 8/231:39 pm
PTY
- SFO
2 stops23h 47m
American Airlines
Deal found 7/19![American Airlines logo]()
$830
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/191:07 pm
SFO
- PTY
1 stop15h 15m
Multiple Airlines
Sun 9/61:54 pm
PTY
- SFO
1 stop11h 18m
Multiple Airlines
Deal found 7/23![Multiple Airlines logo]()
$788
This United Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1912:45 am
SFO
- PTY
1 stop11h 29m
United Airlines
Fri 9/43:30 pm
PTY
- SFO
1 stop10h 57m
United Airlines
Deal found 7/23![United Airlines logo]()
$821
This Copa Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/198:21 pm
SFO
- DAV
1 stop10h 47m
Copa Airlines
Wed 8/269:50 am
DAV
- SFO
1 stop15h 50m
Copa Airlines
Deal found 7/20![Copa Airlines logo]()
$1,126
This Delta deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/204:05 pm
SFO
- PTY
1 stop18h 50m
Delta
Thu 9/102:23 pm
PTY
- SFO
2 stops21h 54m
Delta
Deal found 7/23![Delta logo]()
$825
This oojo deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/297:00 am
SFO
- PTY
1 stop11h 44m
Multiple Airlines
Wed 9/231:54 pm
PTY
- SFO
1 stop11h 18m
Multiple Airlines
Deal found 7/21![Multiple Airlines logo]()
$839
This Copa Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/301:12 am
SFO
- PTY
Nonstop7h 15m
Copa Airlines
Wed 9/912:38 pm
PTY
- SFO
Nonstop7h 32m
Copa Airlines
Deal found 7/21![Copa Airlines logo]()
$791
This United Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/3012:45 am
SFO
- PTY
1 stop15h 52m
United Airlines
Wed 9/93:30 pm
PTY
- SFO
1 stop20h 00m
United Airlines
Deal found 7/21![United Airlines logo]()
$806
This American Airlines deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/319:35 pm
SFO
- PTY
1 stop13h 04m
American Airlines
Wed 9/91:16 pm
PTY
- SFO
2 stops21h 40m
American Airlines
Deal found 7/18![American Airlines logo]()
$810
One-way flights from San Francisco to PanamaSearch for one-way flight options from San Francisco to Panama. Find affordable one-way fares based on user searches. Data last updated July 24, 2026.
Search for one-way flight options from San Francisco to Panama. Find affordable one-way fares based on user searches. Data last updated July 24, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/2611:20 am
SFO
- PTY
3 stops24h 45m
Multiple Airlines
Deal found 7/22![Multiple Airlines logo]()
$331
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/248:23 pm
SFO
- PTY
2 stops15h 42m
Multiple Airlines
Deal found 7/22![Multiple Airlines logo]()
$347
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/258:23 pm
SFO
- PTY
2 stops39h 42m
Multiple Airlines
Deal found 7/22![Multiple Airlines logo]()
$348
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1210:07 pm
SFO
- PTY
2 stops38h 03m
Multiple Airlines
Deal found 7/22![Multiple Airlines logo]()
$351
This Kiwi.com deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/610:35 pm
SFO
- PTY
2 stops31h 55m
Multiple Airlines
Deal found 7/20![Multiple Airlines logo]()
$352
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1110:48 pm
SFO
- PTY
2 stops31h 22m
Multiple Airlines
Deal found 7/22![Multiple Airlines logo]()
$366
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/177:17 pm
SFO
- PTY
2 stops22h 12m
Multiple Airlines
Deal found 7/22![Multiple Airlines logo]()
$369
This Kiwi.com deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/710:35 pm
SFO
- PTY
2 stops31h 35m
Multiple Airlines
Deal found 7/21![Multiple Airlines logo]()
$373
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/188:00 am
SFO
- PTY
3 stops21h 20m
Multiple Airlines
Deal found 7/22![Multiple Airlines logo]()
$391
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/18:23 pm
SFO
- DAV
3 stops20h 54m
Multiple Airlines
Deal found 7/22![Multiple Airlines logo]()
$566
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/118:57 pm
SFO
- PAC
3 stops43h 33m
Multiple Airlines
Deal found 7/22![Multiple Airlines logo]()
$860
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/121:51 pm
SFO
- PAC
3 stops26h 39m
Multiple Airlines
Deal found 7/22![Multiple Airlines logo]()
$861
Find flight deals from San Francisco to Panama
Keep the following information in mind while searching for San Francisco to Panama flight deals. Data was last updated July 24, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $704 (Booking.com) |
One-way from | $331 (Kiwi.com) |
Popular in | December |
Cheapest in | October |
Average price | $816 |
Good round-trip deal | $767 or less |
Good one-way deal | $368 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from San Francisco to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 24, 2026.
Use the filters below to find and compare flights from San Francisco to Panama that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San FranciscoPanama City
SFO - PTY
SFOPTY
San Francisco
Sat 1/16
12:40 am-10:46 am
Nonstop7h 06m
Panama City Tocumen Intl
Sat 1/23
6:31 pm-11:15 pm
Nonstop7h 44m
$776
San FranciscoPanama City
SFO - PTY
SFOPTY
San Francisco
Wed 10/21
5:00 am-6:37 pm
1 stop11h 37m
Panama City Tocumen Intl
Mon 10/26
7:55 am-12:36 am
3 stops18h 41m
$791
San FranciscoPanama City
SFO - PTY
SFOPTY
San Francisco
Sun 10/11
12:45 am-6:37 pm
1 stop15h 52m
Panama City Tocumen Intl
Fri 10/16
3:30 pm-11:47 pm
1 stop10h 17m
$791
San FranciscoPanama City
SFO - PTY
SFOPTY
San Francisco
Sun 10/11
1:12 am-10:27 am
Nonstop7h 15m
Panama City Tocumen Intl
Sun 10/25
6:08 pm-11:40 pm
Nonstop7h 32m
$791
San FranciscoPanama City
SFO - PTY
SFOPTY
San Francisco
Wed 12/9
12:45 am-5:12 pm
1 stop13h 27m
Panama City Tocumen Intl
Mon 12/14
8:55 am-12:04 am
1 stop18h 09m
$791
Quickest round-trip
San FranciscoPanama City
SFO - PTY
SFOPTY
San Francisco
Thu 9/24
8:21 pm-5:35 am
Nonstop7h 14m
Panama City Tocumen Intl
Wed 10/14
12:38 pm-6:10 pm
Nonstop7h 32m
$791
San FranciscoPanama City
SFO - PTY
SFOPTY
San Francisco
Sun 12/6
12:45 am-2:45 pm
1 stop11h 00m
Panama City Tocumen Intl
Mon 12/14
11:35 am-12:04 am
1 stop15h 29m
$791
San FranciscoPanama City
SFO - PTY
SFOPTY
San Francisco
Wed 12/9
12:33 am-10:46 am
Nonstop7h 13m
Panama City Tocumen Intl
Mon 12/14
6:31 pm-11:17 pm
Nonstop7h 46m
$791
San FranciscoPanama City
SFO - PTY
SFOPTY
San Francisco
Sat 1/9
11:59 pm-7:38 pm
1 stop16h 39m
Panama City Tocumen Intl
Sat 1/16
11:35 am-10:39 pm
1 stop14h 04m
$791
San FranciscoDavid
SFO - DAV
SFODAV
San Francisco
Fri 9/4
1:12 am-7:17 pm
1 stop16h 05m
David Enrique Malek
Sat 9/12
7:57 pm-6:10 pm
1 stop24h 13m
$1,126
Showing 1-10 of 35 resultsSorted by cheapest first
Best time to book a flight from San Francisco to Panama
Have a flexible travel schedule? Discover the best time to fly to Panama from San Francisco with our price prediction graph.
SFO-PTY
SFO-DAV
SFO-PAC
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Francisco to Panama
SFO-PA0
SFO-PTY
SFO-DAV
SFO-PAC
What is the cheapest month to book a flight from San Francisco to Panama?
Currently, October is the cheapest month in which you can book a flight from San Francisco to Panama (average of $536). Flying from San Francisco to Panama in December is currently the most expensive (average of $890). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from SFO to PA?
Find hourly flight availability from San Francisco to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 24, 2026.
When flying from San Francisco to Panama, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
Weekly flight availability from San Francisco to Panama
Explore weekly flight availability from San Francisco to Panama. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated July 24, 2026.
The most flights from SFO to PA0 are scheduled on a Tuesday (4 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (1 on average).
How often are flights from San Francisco to Panama delayed?
About 9% of weekly flights between San Francisco and Panama have experienced delays in the past year, with the average delay time being 112 minutes.
What is the most punctual flight time for San Francisco to Panama flights?
Historically, flights departing at night are less likely to be delayed, whereas flights leaving in the morning tend to experience delays more often.
What day of the week experiences the fewest flight delays on this route?
Monday tends to have the lowest number of delays on this route, whereas Wednesday has historically faced a higher average of delays compared to other days of the week.
Which airline has the best punctuality record on San Francisco to Panama flights?
Over the last year, Copa Airlines have had the lowest number of delays on this route, with just 6% of flights being delayed.
How far ahead should I book a flight from San Francisco to Panama?
Booking 48 days in advance of your planned departure date is, on average, the best time to get cheap flights from San Francisco to Panama. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
Reviews of airlines servicing Panama
Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated July 24, 2026.
Read reviews from past customers who have flown Delta,Copa Airlines, andUnited Airlines from San Francisco to Panama. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.2
Boarding
8.1
Overall
7.8
Entertainment
7.8
Crew
8.5
Comfort
7.8
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Food
7.2
Boarding
8.1
Overall
7.8
Entertainment
7.8
Crew
8.5
Comfort
7.8
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Food
7.2
Boarding
8.1
Overall
7.8
Entertainment
7.8
Crew
8.5
Comfort
7.8
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Food
7.2
Boarding
8.1
Overall
7.8
Entertainment
7.8
Crew
8.5
Comfort
7.8
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Food
7.2
Boarding
8.1
Overall
7.8
Entertainment
7.8
Crew
8.5
Comfort
7.8
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Food
7.2
Boarding
8.1
Overall
7.8
Entertainment
7.8
Crew
8.5
Comfort
7.8
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Related info for your journey
Find useful and relevant information for your journey from San Francisco to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for San Francisco to Panama
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Complete your trip
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Find flights from San Francisco to Panama, based on your preferred cabin class, be it economy, premium economy, business, or first class.
San Francisco and Panama flights
Browse other San Francisco and Panama flight options. Last updated on July 24, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 5 airlines flying from San Francisco to Panama
Discover the top 5 airlines that operate flights from San Francisco to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 24, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$234 | Average$538 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$471 | Average$696 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$519 | Average$875 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$536 | Average$803 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$588 | Average$982 | FlexibilityNo cancel fee | On-time71% |