$345+ Cheap flights from San Francisco (SFO) to Panama
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/12. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — PTY
Nov 24 — Dec 11
Round-trip
1 adult, Economy
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Find cheap flights from San Francisco to Panama with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from San Francisco to PanamaExplore the most affordable flight options available from San Francisco to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 25, 2026.
Explore the most affordable flight options available from San Francisco to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 25, 2026.
This Mytrip deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1012:20 pm -
3 stops23h 55m
Mon 11/162:30 am -
3 stops35h 47m
Deal found 10/24![Multiple Airlines logo]()
$791
This Kiwi.com deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/52:22 pm -
3 stops44h 24m
Sat 12/1212:40 pm -
Nonstop7h 45m
Deal found 10/24![Multiple Airlines logo]()
$794
This SmartFares deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/101:15 pm -
1 stop9h 55m
Tue 11/175:30 am -
1 stop9h 25m
Deal found 10/24![Avianca logo]()
$807
This Avianca deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/151:15 pm -
1 stop9h 55m
Mon 11/235:30 am -
1 stop19h 10m
Deal found 10/20![Avianca logo]()
$810
This Avianca deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/111:15 pm -
1 stop9h 55m
Tue 11/175:30 am -
1 stop19h 10m
Deal found 10/24![Avianca logo]()
$819
This Avianca deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/301:15 pm -
1 stop9h 55m
Mon 12/145:30 am -
1 stop19h 10m
Deal found 10/21![Avianca logo]()
$820
This Mytrip deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1112:20 pm -
3 stops25h 55m
Tue 11/1710:05 am -
3 stops28h 12m
Deal found 10/24![Multiple Airlines logo]()
$823
This Kiwi.com deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/58:32 pm -
2 stops38h 14m
Mon 12/76:31 pm -
Nonstop7h 46m
Deal found 10/22![Multiple Airlines logo]()
$830
This FlightHub deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/111:15 pm -
1 stop9h 55m
Sat 11/145:30 am -
1 stop9h 25m
Deal found 10/23![Avianca logo]()
$832
This Kiwi.com deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/222:15 pm -
1 stop9h 40m
Mon 10/265:30 am -
1 stop9h 25m
Deal found 10/22![Avianca logo]()
$836
This Copa Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/812:33 am -
1 stop15h 26m
Wed 11/189:48 am -
1 stop16h 24m
Deal found 10/20![Copa Airlines logo]()
$1,291
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/2411:59 pm -
2 stops29h 51m
Tue 12/19:48 am -
2 stops24h 32m
Deal found 10/25![United Airlines logo]()
$1,346
Best flights from San Francisco to PanamaDiscover carefully curated flight deals from San Francisco to Panama that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 25, 2026.
Discover carefully curated flight deals from San Francisco to Panama that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 25, 2026.
This Copa Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/1712:40 am -
Nonstop7h 06m
Wed 1/2712:40 pm -
Nonstop7h 45m
Deal found 10/25![Copa Airlines logo]()
$856
This United Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/96:36 pm -
1 stop19h 36m
Sat 1/164:41 pm -
1 stop10h 49m
Deal found 10/23![United Airlines logo]()
$871
This FlightHub deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/21:15 pm -
2 stops16h 34m
Sat 2/67:51 pm -
2 stops19h 04m
Deal found 10/22![Multiple Airlines logo]()
$1,519
This Copa Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/712:42 am -
Nonstop7h 04m
Tue 2/1612:38 pm -
Nonstop7h 47m
Deal found 10/24![Copa Airlines logo]()
$856
This United Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/912:30 am -
1 stop11h 15m
Sat 1/164:41 pm -
1 stop10h 49m
Deal found 10/24![United Airlines logo]()
$871
This Copa Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/157:36 pm -
Nonstop7h 03m
Fri 1/2212:40 pm -
Nonstop7h 45m
Deal found 10/25![Copa Airlines logo]()
$856
This Copa Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/27:55 pm -
Nonstop6h 52m
Sun 4/115:56 pm -
Nonstop7h 44m
Deal found 10/25![Copa Airlines logo]()
$871
This Copa Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/1112:42 am -
Nonstop7h 04m
Mon 2/156:31 pm -
Nonstop7h 46m
Deal found 10/25![Copa Airlines logo]()
$871
This Copa Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/2812:40 am -
Nonstop7h 06m
Wed 2/106:31 pm -
Nonstop7h 46m
Deal found 10/24![Copa Airlines logo]()
$871
This Copa Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/1712:42 am -
Nonstop7h 04m
Mon 3/16:31 pm -
Nonstop7h 44m
Deal found 10/23![Copa Airlines logo]()
$871
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/3112:30 am -
2 stops29h 19m
Sun 2/79:47 am -
2 stops24h 40m
Deal found 10/22![United Airlines logo]()
$1,316
This Copa Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/37:55 pm -
Nonstop6h 52m
Sat 4/105:56 pm -
Nonstop7h 44m
Deal found 10/24![Copa Airlines logo]()
$871
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/145:00 am -
2 stops24h 49m
Tue 2/239:47 am -
2 stops26h 48m
Deal found 10/20![United Airlines logo]()
$1,331
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/2411:59 pm -
2 stops29h 51m
Tue 12/19:48 am -
2 stops24h 32m
Deal found 10/25![United Airlines logo]()
$1,346
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/227:10 pm -
2 stops34h 39m
Fri 2/269:47 am -
2 stops36h 00m
Deal found 10/20![United Airlines logo]()
$1,346
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/95:00 am -
2 stops24h 50m
Wed 11/189:48 am -
2 stops38h 13m
Deal found 10/25![United Airlines logo]()
$1,469
This Copa Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/812:33 am -
1 stop15h 26m
Wed 11/189:48 am -
1 stop16h 24m
Deal found 10/20![Copa Airlines logo]()
$1,291
Last-minute flights from San Francisco to PanamaDiscover last-minute flight deals from San Francisco to Panama. Data last updated October 25, 2026 and is based on user searches.
Discover last-minute flight deals from San Francisco to Panama. Data last updated October 25, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/222:15 pm -
1 stop9h 40m
Mon 10/265:30 am -
1 stop9h 25m
Deal found 10/22![Avianca logo]()
$836
This Avianca deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/282:15 pm -
2 stops16h 55m
Mon 11/25:30 am -
1 stop19h 10m
Deal found 10/24![Avianca logo]()
$830
This Copa Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/812:33 am -
1 stop15h 26m
Wed 11/189:48 am -
1 stop16h 24m
Deal found 10/20![Copa Airlines logo]()
$1,291
This Mytrip deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1012:20 pm -
3 stops23h 55m
Mon 11/162:30 am -
3 stops35h 47m
Deal found 10/24![Multiple Airlines logo]()
$791
This SmartFares deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/101:15 pm -
1 stop9h 55m
Tue 11/175:30 am -
1 stop9h 25m
Deal found 10/24![Avianca logo]()
$807
This Avianca deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/111:15 pm -
1 stop9h 55m
Tue 11/175:30 am -
1 stop19h 10m
Deal found 10/24![Avianca logo]()
$819
This Mytrip deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1112:20 pm -
3 stops25h 55m
Tue 11/1710:05 am -
3 stops28h 12m
Deal found 10/24![Multiple Airlines logo]()
$823
This FlightHub deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/111:15 pm -
1 stop9h 55m
Sat 11/145:30 am -
1 stop9h 25m
Deal found 10/23![Avianca logo]()
$832
This Avianca deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/151:15 pm -
1 stop9h 55m
Mon 11/236:10 pm -
2 stops20h 45m
Deal found 10/20![Avianca logo]()
$810
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/2411:59 pm -
2 stops29h 51m
Tue 12/19:48 am -
2 stops24h 32m
Deal found 10/25![United Airlines logo]()
$1,346
This Avianca deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/301:15 pm -
1 stop9h 55m
Mon 12/145:30 am -
1 stop19h 10m
Deal found 10/21![Avianca logo]()
$820
This FlightHub deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/301:15 pm -
1 stop9h 55m
Mon 12/75:30 am -
1 stop9h 25m
Deal found 10/22![Avianca logo]()
$842
One-way flights from San Francisco to PanamaSearch for one-way flight options from San Francisco to Panama. Find affordable one-way fares based on user searches. Data last updated October 25, 2026.
Search for one-way flight options from San Francisco to Panama. Find affordable one-way fares based on user searches. Data last updated October 25, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/126:30 pm -
3 stops42h 31m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/22![Multiple Airlines logo]()
$345
This Kiwi.com deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/1111:06 am -
3 stops29h 39m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/22![Multiple Airlines logo]()
$359
This Kiwi.com deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/139:44 am -
3 stops27h 17m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/22![Multiple Airlines logo]()
$365
This Kiwi.com deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/810:29 am -
2 stops24h 17m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/24![Multiple Airlines logo]()
$376
This Kiwi.com deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/912:59 pm -
2 stops21h 34m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/24![Multiple Airlines logo]()
$379
This Kiwi.com deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/16:30 pm -
3 stops34h 19m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/25![Multiple Airlines logo]()
$380
This Kiwi.com deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/77:00 pm -
2 stops39h 33m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/22![Multiple Airlines logo]()
$383
This Kiwi.com deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/306:00 pm -
3 stops40h 33m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/23![Multiple Airlines logo]()
$384
This Kiwi.com deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/92:22 pm -
2 stops44h 24m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/24![Multiple Airlines logo]()
$386
This Kiwi.com deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/16:30 pm -
3 stops58h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/23![Multiple Airlines logo]()
$509
This Kiwi.com deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/229:15 am -
3 stops54h 44m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/23![Multiple Airlines logo]()
$637
This Copa Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/17:36 pm -
1 stop10h 09m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/23![Copa Airlines logo]()
$963
Find flight deals from San Francisco to Panama
Keep the following information in mind while searching for San Francisco to Panama flight deals. Data was last updated October 25, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $791 (Mytrip) |
One-way from | $345 (Kiwi.com) |
Popular in | December |
Cheapest in | April |
Average price | $840 |
Good round-trip deal | $780 or less |
Good one-way deal | $691 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from San Francisco to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 25, 2026.
Use the filters below to find and compare flights from San Francisco to Panama that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San FranciscoDavid
SFO San Francisco - DAV David Enrique Malek
SFODAV
San Francisco
Tue 12/1
6:30 pm-8:00 am
3 stops58h 30m
David Enrique Malek
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$509
San FranciscoPanama City
SFO San Francisco - PTY Panama City Tocumen Intl
SFOPTY
San Francisco
Mon 1/18
12:00 pm-5:03 pm
2 stops26h 03m
Panama City Tocumen Intl
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$525
San FranciscoPanama City
SFO San Francisco - PTY Panama City Tocumen Intl
SFOPTY
San Francisco
Fri 12/18
9:23 pm-2:01 pm
2 stops37h 38m
Panama City Tocumen Intl
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$707
San FranciscoPanama City
SFO San Francisco - PTY Panama City Tocumen Intl
SFOPTY
San Francisco
Mon 1/18
12:30 am-5:12 pm
1 stop13h 42m
Panama City Tocumen Intl
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$756
San FranciscoPanama City
SFO San Francisco - PTY Panama City Tocumen Intl
SFOPTY
San Francisco
Thu 12/3
4:27 pm-2:45 pm
1 stop19h 18m
Panama City Tocumen Intl
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$786
San FranciscoPanama City
SFO San Francisco - PTY Panama City Tocumen Intl
SFOPTY
San Francisco
Sun 12/20
6:35 pm-2:45 pm
1 stop17h 10m
Panama City Tocumen Intl
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$795
San FranciscoPanama City
SFO San Francisco - PTY Panama City Tocumen Intl
SFOPTY
San Francisco
Tue 11/3
4:40 pm-2:45 pm
1 stop19h 05m
Panama City Tocumen Intl
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$795
San FranciscoPanama City
SFO San Francisco - PTY Panama City Tocumen Intl
SFOPTY
San Francisco
Sun 1/17
12:40 am-10:46 am
Nonstop7h 06m
Panama City Tocumen Intl
Wed 1/27
12:40 pm-5:25 pm
Nonstop7h 45m
$856
San FranciscoPanama City
SFO San Francisco - PTY Panama City Tocumen Intl
SFOPTY
San Francisco
Sun 2/7
12:42 am-10:46 am
Nonstop7h 04m
Panama City Tocumen Intl
Tue 2/16
12:38 pm-5:25 pm
Nonstop7h 47m
$856
San FranciscoPanama City
SFO San Francisco - PTY Panama City Tocumen Intl
SFOPTY
San Francisco
Fri 1/15
7:36 pm-5:39 am
Nonstop7h 03m
Panama City Tocumen Intl
Fri 1/22
12:40 pm-5:25 pm
Nonstop7h 45m
$856
Showing 1-10 of 31 resultsSorted by cheapest first
Best time to book a flight from San Francisco to Panama
Have a flexible travel schedule? Discover the best time to fly to Panama from San Francisco with our price prediction graph.
SFO-DAV
SFO-PTY
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Francisco to Panama
SFO-PA0
SFO-DAV
SFO-PTY
What is the cheapest month to book a flight from San Francisco to Panama?
Currently, April is the cheapest month in which you can book a flight from San Francisco to Panama (average of $674). Flying from San Francisco to Panama in December is currently the most expensive (average of $1,038). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from SFO to PA?
Find hourly flight availability from San Francisco to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 25, 2026.
When flying from San Francisco to Panama, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
How often are flights from San Francisco to Panama delayed?
About 7% of weekly flights between San Francisco and Panama have experienced delays in the past year, with the average delay time being 105 minutes.
What is the most punctual flight time for San Francisco to Panama flights?
Historically, flights departing at night are less likely to be delayed, whereas flights leaving in the morning tend to experience delays more often.
What day of the week experiences the fewest flight delays on this route?
Monday tends to have the lowest number of delays on this route, whereas Tuesday has historically faced a higher average of delays compared to other days of the week.
Which airline has the best punctuality record on San Francisco to Panama flights?
Over the last year, Copa Airlines have had the lowest number of delays on this route, with just 6% of flights being delayed.
How far ahead should I book a flight from San Francisco to Panama?
Booking 19 days in advance of your planned departure date is, on average, the best time to get cheap flights from San Francisco to Panama. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
Reviews of airlines servicing Panama
Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated October 25, 2026.
Read reviews from past customers who have flown Copa Airlines,United Airlines, andAvianca from San Francisco to Panama. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
7.8
Crew
8.1
Food
7.0
Entertainment
6.9
Overall
7.6
Comfort
7.5
Reviews
1 / 20
2.0
MediocreAnonymous,Oct 2026
BOS - PTY
Boarding
7.8
Crew
8.1
Food
7.0
Entertainment
6.9
Overall
7.6
Comfort
7.5
Reviews
1 / 20
2.0
MediocreAnonymous,Oct 2026
BOS - PTY
Boarding
7.8
Crew
8.1
Food
7.0
Entertainment
6.9
Overall
7.6
Comfort
7.5
Reviews
1 / 20
2.0
MediocreAnonymous,Oct 2026
BOS - PTY
Boarding
7.8
Crew
8.1
Food
7.0
Entertainment
6.9
Overall
7.6
Comfort
7.5
Reviews
1 / 20
2.0
MediocreAnonymous,Oct 2026
BOS - PTY
Related info for your journey
Find useful and relevant information for your journey from San Francisco to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for San Francisco to Panama
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Panama by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from San Francisco to Panama by cabin class
Find flights from San Francisco to Panama, based on your preferred cabin class, be it economy, premium economy, business, or first class.
San Francisco and Panama flights
Browse other San Francisco and Panama flight options. Last updated on October 25, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from San Francisco to Panama
Discover the top 3 airlines that operate flights from San Francisco to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 25, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$227 | Average$596 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$498 | Average$815 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$600 | Average$898 | FlexibilityNo cancel fee | On-time69% |