$389+ Cheap flights from Panama to San Francisco (SFO)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/13. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — SFO
Nov 24 — Dec 11
Round-trip
1 adult, Economy
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Find cheap flights from Panama to San Francisco with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Panama to San Francisco
Cheapest
Best
Last-minute
One-way
Cheapest flights from Panama to San FranciscoExplore the most affordable flight options available from Panama to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 25, 2026.
Explore the most affordable flight options available from Panama to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 25, 2026.
This Avianca deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/235:30 am -
1 stop9h 20m
Sun 10/252:15 pm -
1 stop9h 55m
Deal found 10/22![Avianca logo]()
$681
This Avianca deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/45:30 am -
1 stop19h 10m
Tue 11/101:15 pm -
1 stop9h 55m
Deal found 10/20![Avianca logo]()
$691
This Avianca deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1710:05 am -
2 stops14h 35m
Tue 12/81:15 pm -
1 stop9h 55m
Deal found 10/20![Avianca logo]()
$701
This Avianca deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2210:10 am -
2 stops14h 25m
Sat 10/312:15 pm -
1 stop9h 55m
Deal found 10/20![Avianca logo]()
$705
This Avianca deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/35:30 am -
1 stop19h 10m
Tue 11/101:15 pm -
1 stop9h 55m
Deal found 10/20![Avianca logo]()
$711
This Delta deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/292:24 pm -
1 stop11h 32m
Tue 11/109:42 pm -
1 stop13h 20m
Deal found 10/23![Delta logo]()
$714
This FlightHub deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/185:30 am -
1 stop9h 25m
Tue 12/81:15 pm -
1 stop9h 55m
Deal found 10/20![Avianca logo]()
$727
This Copa Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:08 pm -
Nonstop7h 32m
Sun 11/812:33 am -
Nonstop7h 13m
Deal found 10/21![Copa Airlines logo]()
$730
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/303:41 pm -
1 stop20h 29m
Mon 11/94:40 pm -
1 stop23h 58m
Deal found 10/21![United Airlines logo]()
$735
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/234:33 pm -
1 stop21h 29m
Mon 1/410:52 pm -
2 stops13h 41m
Deal found 10/21![American Airlines logo]()
$736
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/134:41 pm -
1 stop17h 47m
Tue 11/175:00 am -
1 stop11h 38m
Deal found 10/22![United Airlines logo]()
$744
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/43:13 pm -
2 stops21h 50m
Sun 11/83:45 pm -
2 stops19h 28m
Deal found 10/21![American Airlines logo]()
$749
Best flights from Panama to San FranciscoDiscover carefully curated flight deals from Panama to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 25, 2026.
Discover carefully curated flight deals from Panama to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 25, 2026.
This Copa Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/26:31 pm -
Nonstop7h 41m
Sat 11/712:33 am -
Nonstop7h 13m
Deal found 10/21![Copa Airlines logo]()
$730
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/48:55 am -
1 stop12h 52m
Fri 12/116:41 pm -
1 stop17h 04m
Deal found 10/20![United Airlines logo]()
$735
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/23:24 pm -
1 stop11h 32m
Fri 11/611:30 pm -
1 stop11h 29m
Deal found 10/20![Delta logo]()
$735
This Copa Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/16:31 pm -
Nonstop7h 41m
Sun 11/812:33 am -
Nonstop7h 13m
Deal found 10/21![Copa Airlines logo]()
$730
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/38:55 am -
1 stop14h 15m
Sat 12/125:00 am -
1 stop9h 12m
Deal found 10/21![United Airlines logo]()
$735
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/178:55 am -
1 stop14h 03m
Tue 11/242:30 pm -
1 stop26h 08m
Deal found 10/20![United Airlines logo]()
$735
This Copa Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/246:31 pm -
Nonstop7h 41m
Thu 11/2612:33 am -
Nonstop7h 13m
Deal found 10/23![Copa Airlines logo]()
$754
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/14:41 pm -
1 stop22h 38m
Mon 11/96:35 pm -
1 stop22h 03m
Deal found 10/21![United Airlines logo]()
$735
This United Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/54:41 pm -
1 stop20h 10m
Sat 12/125:00 am -
1 stop11h 38m
Deal found 10/23![United Airlines logo]()
$744
This Copa Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/26:31 pm -
Nonstop7h 41m
Thu 11/512:33 am -
Nonstop7h 13m
Deal found 10/20![Copa Airlines logo]()
$885
This United Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/134:41 pm -
1 stop17h 47m
Tue 11/175:00 am -
1 stop11h 38m
Deal found 10/24![United Airlines logo]()
$744
Last-minute flights from Panama to San FranciscoDiscover last-minute flight deals from Panama to San Francisco. Data last updated October 25, 2026 and is based on user searches.
Discover last-minute flight deals from Panama to San Francisco. Data last updated October 25, 2026 and is based on user searches.
This Avianca deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2210:10 am -
2 stops14h 25m
Sat 10/312:15 pm -
1 stop9h 55m
Deal found 10/20![Avianca logo]()
$705
This Avianca deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/235:30 am -
1 stop9h 20m
Sun 10/252:15 pm -
1 stop9h 55m
Deal found 10/22![Avianca logo]()
$681
This Delta deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/292:24 pm -
1 stop11h 32m
Tue 11/109:42 pm -
1 stop13h 20m
Deal found 10/23![Delta logo]()
$714
This Copa Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:08 pm -
Nonstop7h 32m
Sun 11/812:33 am -
Nonstop7h 13m
Deal found 10/21![Copa Airlines logo]()
$730
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/303:41 pm -
1 stop20h 29m
Mon 11/94:40 pm -
1 stop23h 58m
Deal found 10/21![United Airlines logo]()
$735
This Avianca deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/35:30 am -
1 stop19h 10m
Tue 11/101:15 pm -
1 stop9h 55m
Deal found 10/20![Avianca logo]()
$711
This Avianca deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/45:30 am -
1 stop19h 10m
Tue 11/101:15 pm -
1 stop9h 55m
Deal found 10/20![Avianca logo]()
$691
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/43:13 pm -
2 stops20h 27m
Sun 11/86:32 pm -
2 stops16h 41m
Deal found 10/21![American Airlines logo]()
$736
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/134:41 pm -
1 stop17h 47m
Tue 11/175:00 am -
1 stop11h 38m
Deal found 10/22![United Airlines logo]()
$744
This Avianca deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1710:05 am -
2 stops14h 35m
Tue 12/81:15 pm -
1 stop9h 55m
Deal found 10/20![Avianca logo]()
$701
This FlightHub deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/185:30 am -
1 stop9h 25m
Tue 12/81:15 pm -
1 stop9h 55m
Deal found 10/20![Avianca logo]()
$727
One-way flights from Panama to San FranciscoSearch for one-way flight options from Panama to San Francisco. Find affordable one-way fares based on user searches. Data last updated October 25, 2026.
Search for one-way flight options from Panama to San Francisco. Find affordable one-way fares based on user searches. Data last updated October 25, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/136:15 pm -
2 stops31h 14m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![Multiple Airlines logo]()
$389
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/153:13 pm -
2 stops24h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/22![American Airlines logo]()
$390
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/214:55 pm -
1 stop21h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![American Airlines logo]()
$394
This Copa Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/412:44 pm -
Nonstop7h 41m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Copa Airlines logo]()
$395
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/44:41 pm -
1 stop27h 29m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![United Airlines logo]()
$401
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/297:55 am -
1 stop18h 09m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![United Airlines logo]()
$405
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/43:13 pm -
2 stops24h 08m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![American Airlines logo]()
$410
This Booking.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1012:44 pm -
Nonstop7h 41m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![Copa Airlines logo]()
$411
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/108:16 am -
2 stops30h 01m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![Multiple Airlines logo]()
$420
Find flight deals from Panama to San Francisco
Keep the following information in mind while searching for Panama to San Francisco flight deals. Data was last updated October 25, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $681 (Avianca) |
One-way from | $389 (Kiwi.com) |
Popular in | October |
Cheapest in | April |
Average price | $866 |
Good round-trip deal | $729 or less |
Good one-way deal | $581 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Panama to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 25, 2026.
Use the filters below to find and compare flights from Panama to San Francisco that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
Panama CitySan Francisco
PTY Panama City Tocumen Intl - SFO San Francisco
PTYSFO
Panama City Tocumen Intl
Thu 11/12
6:31 pm-11:12 pm
Nonstop7h 41m
San Francisco
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$395
Panama CitySan Francisco
PTY Panama City Tocumen Intl - SFO San Francisco
PTYSFO
Panama City Tocumen Intl
Wed 11/11
4:41 pm-12:04 am
1 stop10h 23m
San Francisco
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$401
Panama CitySan Francisco
PTY Panama City Tocumen Intl - SFO San Francisco
PTYSFO
Panama City Tocumen Intl
Thu 10/29
7:55 am-12:04 am
1 stop18h 09m
San Francisco
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$405
Panama CitySan Francisco
PTY Panama City Tocumen Intl - SFO San Francisco
PTYSFO
Panama City Tocumen Intl
Sun 1/31
4:55 pm-11:15 am
1 stop21h 20m
San Francisco
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$476
Panama CitySan Francisco
PTY Panama City Tocumen Intl - SFO San Francisco
PTYSFO
Panama City Tocumen Intl
Mon 11/2
6:31 pm-11:12 pm
Nonstop7h 41m
San Francisco
Sat 11/7
12:33 am-10:46 am
Nonstop7h 13m
$730
Panama CitySan Francisco
PTY Panama City Tocumen Intl - SFO San Francisco
PTYSFO
Panama City Tocumen Intl
Sun 11/1
6:31 pm-11:12 pm
Nonstop7h 41m
San Francisco
Sun 11/8
12:33 am-10:46 am
Nonstop7h 13m
$730
Panama CitySan Francisco
PTY Panama City Tocumen Intl - SFO San Francisco
PTYSFO
Panama City Tocumen Intl
Fri 12/4
8:55 am-6:47 pm
1 stop12h 52m
San Francisco
Fri 12/11
6:41 pm-2:45 pm
1 stop17h 04m
$735
Panama CitySan Francisco
PTY Panama City Tocumen Intl - SFO San Francisco
PTYSFO
Panama City Tocumen Intl
Mon 11/2
3:24 pm-11:56 pm
1 stop11h 32m
San Francisco
Fri 11/6
11:30 pm-1:59 pm
1 stop11h 29m
$735
Panama CitySan Francisco
PTY Panama City Tocumen Intl - SFO San Francisco
PTYSFO
Panama City Tocumen Intl
Thu 12/3
8:55 am-8:10 pm
1 stop14h 15m
San Francisco
Sat 12/12
5:00 am-5:12 pm
1 stop9h 12m
$735
Panama CitySan Francisco
PTY Panama City Tocumen Intl - SFO San Francisco
PTYSFO
Panama City Tocumen Intl
Tue 11/17
8:55 am-7:58 pm
1 stop14h 03m
San Francisco
Tue 11/24
2:30 pm-7:38 pm
1 stop26h 08m
$735
Showing 1-10 of 22 resultsSorted by cheapest first
Best time to book a flight from Panama to San Francisco
Have a flexible travel schedule? Discover the best time to fly to San Francisco from Panama with our price prediction graph.
PTY-SFO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Panama to San Francisco
PA0-SFO
PTY-SFO
What is the cheapest month to book a flight from Panama to San Francisco?
Currently, April is the cheapest month in which you can book a flight from Panama to San Francisco (average of $624). Flying from Panama to San Francisco in December is currently the most expensive (average of $858). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from PA to SFO?
Find hourly flight availability from Panama to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 25, 2026.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Panama to San Francisco as you normally would.
Weekly flight availability from Panama to San Francisco
Explore weekly flight availability from Panama to San Francisco. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated October 25, 2026.
The most flights from PA0 to SFO are scheduled on a Tuesday (2 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (1 on average).
How far ahead should I book a flight from Panama to San Francisco?
Booking 33 days in advance of your planned departure date is, on average, the best time to get cheap flights from Panama to San Francisco. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
Reviews of airlines servicing San Francisco
Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated October 25, 2026.
Read through reviews of airlines operating flights from Panama to San Francisco, such as Copa Airlines,United Airlines, andAvianca. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.4
Crew
8.1
Boarding
7.8
Entertainment
6.9
Overall
7.6
Food
7.0
Reviews
1 / 20
2.0
MediocreMaria,Dec 2025
PTY - SLA
Comfort
7.4
Crew
8.1
Boarding
7.8
Entertainment
6.9
Overall
7.6
Food
7.0
Reviews
1 / 20
2.0
MediocreMaria,Dec 2025
PTY - SLA
Comfort
7.4
Crew
8.1
Boarding
7.8
Entertainment
6.9
Overall
7.6
Food
7.0
Reviews
1 / 20
2.0
MediocreMaria,Dec 2025
PTY - SLA
Comfort
7.4
Crew
8.1
Boarding
7.8
Entertainment
6.9
Overall
7.6
Food
7.0
Reviews
1 / 20
2.0
MediocreMaria,Dec 2025
PTY - SLA
Related info for your journey
Find useful and relevant information for your journey from Panama to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Francisco?
Book flights to San Francisco if you plan to visit one of these locationsSouth San Francisco
Santa Clara
Santa Cruz
Walnut Creek
Hayward
San Bruno
Emeryville
Newark
Burlingame
Roseville
Redwood City
Rancho Cordova
Cupertino
Fairfield
San Ramon
Manteca
San Carlos
Vallejo
Turlock
Davis
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Top 3 airlines flying from Panama to San Francisco
Discover the top 3 airlines that operate flights from Panama to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 25, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$281 | Average$682 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$393 | Average$764 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$679 | Average$878 | FlexibilityNo cancel fee | On-time69% |